Medical College of Wisconsin
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Denise S. Uyar MD

Professor

Institution: Medical College of Wisconsin
Department: Obstetrics and Gynecology
Division: Obstetrics and Gynecology Gynecologic Oncology

Member of the Cancer Center

View Curriculum Vitae

Publications (38)

  • Disparities in Genetic Management of Breast and Ovarian Cancer Patients. (Duyar-Ayerdi S, Summey RM, Uyar D) Obstet Gynecol Surv 2024 Nov;79(11):673-682 PMID: 39547258 SCOPUS ID: 2-s2.0-85209699679 11/16/2024    
  • Carboplatin, paclitaxel, and pembrolizumab followed by pembrolizumab maintenance for primary treatment of incompletely resected epithelial ovarian cancer. (Uyar D, Michener CM, Bishop E, Hopp E, Simpson P, Zhang L, Rader JS, Rose PG, Mahdi HS, Debernardo R, Christian Q, Bradley W) Front Oncol 2024;14:1291090 PMID: 38410102 PMCID: PMC10894939 SCOPUS ID: 2-s2.0-85186485797 02/27/2024       1 Citation
  • Carboplatin, paclitaxel, and pembrolizumab followed by pembrolizumab maintenance for primary treatment of incompletely resected epithelial ovarian cancer (Uyar D, Michener CM, Bishop E, Hopp E, Simpson P, Zhang L, Rader JS, Rose PG, Mahdi HS, Debernardo R, Christian Q, Bradley W) Frontiers in Oncology 2024;14 SCOPUS ID: 2-s2.0-85186485797 01/01/2024       1 Citation
  • Syndromes of Concurrent Hypertension, Diastolic Dysfunction, and Pulmonary or Peripheral Edema in Cardio-Oncology: Case Studies, Literature Review, and New Classification System. (Summey R, Aliani R, McAlarnen LA, Sequeira N, Shaik T, Uyar D, Brown SA) Curr Treat Options Oncol 2023 Dec;24(12):1917-1934 PMID: 38091185 SCOPUS ID: 2-s2.0-85179363175 12/13/2023    
  • A case series of triplet anti-hormonal therapy in androgen receptor-positive recurrent adult ovarian granulosa cell tumor. (Summey RM, Rader JS, Moh M, Bradley W, Uyar D, Bishop E, McAlarnen L, Hopp E) Gynecol Oncol Rep 2022 Dec;44:101118 PMID: 36579182 PMCID: PMC9791298 SCOPUS ID: 2-s2.0-85144072474 12/30/2022       7 Citations
  • Same-Day Discharge After Robotic Hysterectomy: A Resource Utilization and Quality Improvement Project. (McAlarnen LA, Maurer JE, Knaub A, Hopp E, Streitenberger K, Bishop E, Bradley W, Rader J, Uyar D) WMJ 2022 Oct;121(3):243-246 PMID: 36301654 SCOPUS ID: 2-s2.0-85140865266 10/28/2022       3 Citations
  • Ovarian cancer resistance to PARPi and platinum-containing chemotherapy. (Summey R, Uyar D) Cancer Drug Resist 2022;5(3):637-646 PMID: 36176755 PMCID: PMC9511803 SCOPUS ID: 2-s2.0-85133600889 10/01/2022       12 Citations
  • Correction: Parashar et al. Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance. Cancers 2022, 14, 958. (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers (Basel) 2022 May 16;14(10) PMID: 35626175 PMCID: PMC9140135 SCOPUS ID: 2-s2.0-85129951244 05/29/2022       2 Citations
  • Correction to: Parashar et al. Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance (Cancers, (2022), 14, 958) (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers May-2 2022;14(10) SCOPUS ID: 2-s2.0-85129951244 05/01/2022       2 Citations
  • Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance. (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers (Basel) 2022 Feb 15;14(4) PMID: 35205706 PMCID: PMC8870411 SCOPUS ID: 2-s2.0-85124460063 02/26/2022       18 Citations
  • Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers February-2 2022;14(4) SCOPUS ID: 2-s2.0-85124460063 02/01/2022       18 Citations
  • Ovarian cancer resistance to PARPi and platinum-containing chemotherapy (Summey R, Uyar D) Cancer Drug Resistance 2022;5(3):637-646 SCOPUS ID: 2-s2.0-85133600889 01/01/2022       12 Citations
  • Comprehensive serum proteomic analysis in early endometrial cancer (Uyar DS, Huang YW, Chesnik MA, Doan NB, Mirza SP) Journal of Proteomics 15 March 2021;234 SCOPUS ID: 2-s2.0-85099446183 03/15/2021       9 Citations
  • Challenges of Genomic Testing for Hereditary Breast and Ovarian Cancers. (McAlarnen L, Stearns K, Uyar D) Appl Clin Genet 2021;14:1-9 PMID: 33488111 PMCID: PMC7814235 SCOPUS ID: 2-s2.0-85100542019 01/26/2021       19 Citations
  • Comprehensive serum proteomic analysis in early endometrial cancer. (Uyar DS, Huang YW, Chesnik MA, Doan NB, Mirza SP) J Proteomics 2021 Mar 15;234:104099 PMID: 33412313 SCOPUS ID: 2-s2.0-85099446183 01/08/2021       9 Citations
  • Challenges of genomic testing for hereditary breast and ovarian cancers (McAlarnen L, Stearns K, Uyar D) Application of Clinical Genetics 2021;14:1-9 SCOPUS ID: 2-s2.0-85100542019 01/01/2021       19 Citations
  • Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling. (Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cancer Res 2020 Dec 15;80(24):5554-5568 PMID: 33087324 PMCID: PMC7744365 SCOPUS ID: 2-s2.0-85100331032 10/23/2020       36 Citations
  • A Biomarker-enriched, Randomized Phase II Trial of Adavosertib (AZD1775) Plus Paclitaxel and Carboplatin for Women with Platinum-sensitive TP53-mutant Ovarian Cancer. (Oza AM, Estevez-Diz M, Grischke EM, Hall M, Marmé F, Provencher D, Uyar D, Weberpals JI, Wenham RM, Laing N, Tracy M, Freshwater T, Lee MA, Liu J, Qiu J, Rose S, Rubin EH, Moore K) Clin Cancer Res 2020 Sep 15;26(18):4767-4776 PMID: 32611648 SCOPUS ID: 2-s2.0-85092098455 07/03/2020       101 Citations
  • OVARIAN GRANULOSA CELL TUMOR IN A PATIENT WITH A PATHOGENIC VARIANT IN THE CDC73 GENE (HYPERPARATHYROIDISM-JAW TUMOR SYNDROME). (Sirbiladze RL, Uyar D, Geurts JL, Shaker JL) AACE Clin Case Rep 2019;5(3):e222-e225 PMID: 31967039 PMCID: PMC6876943 SCOPUS ID: 2-s2.0-85105277552 01/23/2020       7 Citations
  • SOX11 hypermethylation as a tumor biomarker in endometrial cancer. (Shan T, Uyar DS, Wang LS, Mutch DG, Huang TH, Rader JS, Sheng X, Huang YW) Biochimie 2019 Jul;162:8-14 PMID: 30935961 PMCID: PMC6561798 SCOPUS ID: 2-s2.0-85063759067 04/03/2019       18 Citations
  • Adipose-only sentinel lymph nodes: a finding during the adaptation of a sentinel lymph node mapping algorithm with indocyanine green in women with endometrial cancer. (Harold JA, Uyar D, Rader JS, Bishop E, Nugent M, Simpson P, Bradley WH) Int J Gynecol Cancer 2019 Jan;29(1):53-59 PMID: 30640684 SCOPUS ID: 2-s2.0-85060023480 01/15/2019       11 Citations
  • Phase II study of single-agent cabozantinib in patients with recurrent clear cell ovarian, primary peritoneal or fallopian tube cancer (NRG-GY001). (Konstantinopoulos PA, Brady WE, Farley J, Armstrong A, Uyar DS, Gershenson DM) Gynecol Oncol 2018 Jul;150(1):9-13 PMID: 29739622 PMCID: PMC6365003 SCOPUS ID: 2-s2.0-85046757642 05/10/2018       53 Citations
  • Implementation of a quality improvement project for universal genetic testing in women with ovarian cancer. (Uyar D, Neary J, Monroe A, Nugent M, Simpson P, Geurts JL) Gynecol Oncol 2018 Jun;149(3):565-569 PMID: 29653687 SCOPUS ID: 2-s2.0-85045079578 04/15/2018       23 Citations
  • Integrated genomic and molecular characterization of cervical cancer. (Cancer Genome Atlas Research Network, Albert Einstein College of Medicine, Analytical Biological Services, Barretos Cancer Hospital, Baylor College of Medicine, Beckman Research Institute of City of Hope, Buck Institute for Research on Aging, Canada's Michael Smith Genome Sciences Centre, Harvard Medical School, Helen F. Graham Cancer Center &Research Institute at Christiana Care Health Services, HudsonAlpha Institute for Biotechnology, ILSbio, LLC, Indiana University School of Medicine, Institute of Human Virology, Institute for Systems Biology, International Genomics Consortium, Leidos Biomedical, Massachusetts General Hospital, McDonnell Genome Institute at Washington University, Medical College of Wisconsin, Medical University of South Carolina, Memorial Sloan Kettering Cancer Center, Montefiore Medical Center, NantOmics, National Cancer Institute, National Hospital, Abuja, Nigeria, National Human Genome Research Institute, National Institute of Environmental Health Sciences, National Institute on Deafness &Other Communication Disorders, Ontario Tumour Bank, London Health Sciences Centre, Ontario Tumour Bank, Ontario Institute for Cancer Research, Ontario Tumour Bank, The Ottawa Hospital, Oregon Health &Science University, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, SRA International, St Joseph's Candler Health System, Eli &Edythe L. Broad Institute of Massachusetts Institute of Technology &Harvard University, Research Institute at Nationwide Children's Hospital, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, University of Bergen, University of Texas MD Anderson Cancer Center, University of Abuja Teaching Hospital, University of Alabama at Birmingham, University of California, Irvine, University of California Santa Cruz, University of Kansas Medical Center, University of Lausanne, University of New Mexico Health Sciences Center, University of North Carolina at Chapel Hill, University of Oklahoma Health Sciences Center, University of Pittsburgh, University of São Paulo, Ribeir ão Preto Medical School, University of Southern California, University of Washington, University of Wisconsin School of Medicine &Public Health, Van Andel Research Institute, Washington University in St Louis) Nature 2017 Mar 16;543(7645):378-384 PMID: 28112728 PMCID: PMC5354998 SCOPUS ID: 2-s2.0-85016138846 01/24/2017       1237 Citations
  • A prospective pilot study on the incidence of post-operative lymphedema in women with endometrial cancer. (Hopp EE, Osborne JL, Schneider DK, Bojar CJ, Uyar DS) Gynecol Oncol Rep 2016 Jan;15:25-8 PMID: 26937484 PMCID: PMC4750017 SCOPUS ID: 2-s2.0-84964714816 03/05/2016       26 Citations
  • Ovarian cancer (Rose PG, Uyar DS) Clinical Gynecology Second Edition 1 January 2015:790-812 SCOPUS ID: 2-s2.0-84952887800 01/01/2015    
  • Peer teen advocates and increased awareness of human papillomavirus and vaccination among urban youth (Uyar D, Young S, Tyree-Francis S, Kiepczynski MA) Public Health Improving Health Via Inter Professional Collaborations July 01, 2014:85-94 SCOPUS ID: 2-s2.0-84952947017 07/01/2014    
  • 3-T MRI-based adaptive brachytherapy for cervix cancer: treatment technique and initial clinical outcomes. (Kharofa J, Morrow N, Kelly T, Rownd J, Paulson E, Rader J, Uyar D, Bradley W, Erickson B) Brachytherapy 2014;13(4):319-25 PMID: 24837024 SCOPUS ID: 2-s2.0-84902539256 05/20/2014       30 Citations
  • Hypermethylation of miR-203 in endometrial carcinomas. (Huang YW, Kuo CT, Chen JH, Goodfellow PJ, Huang TH, Rader JS, Uyar DS) Gynecol Oncol 2014 May;133(2):340-5 PMID: 24530564 PMCID: PMC4015135 SCOPUS ID: 2-s2.0-84899624704 02/18/2014       52 Citations
  • Genomics of cervical cancer and the role of human papillomavirus pathobiology. (Uyar D, Rader J) Clin Chem 2014 Jan;60(1):144-6 PMID: 24046199 SCOPUS ID: 2-s2.0-84891821548 09/21/2013       48 Citations
  • Multifocal vulvar smooth muscle tumor with an unusual intravascular growth pattern and multiple local recurrences in a 10-year-old child: a diagnostic dilemma. (Harrington A, Bell E, Suchi M, Behmaram B, Uyar D) Pediatr Dev Pathol 2011;14(3):235-9 PMID: 21090988 SCOPUS ID: 2-s2.0-80054051952 11/26/2010       1 Citation
  • Treatment patterns by decade of life in elderly women (> or =70 years of age) with ovarian cancer. (Uyar D, Frasure HE, Markman M, von Gruenigen VE) Gynecol Oncol 2005 Sep;98(3):403-8 PMID: 16000216 SCOPUS ID: 2-s2.0-23844523788 07/08/2005       110 Citations
  • Cardiac safety profile of prolonged (>or=6 cycles) pegylated liposomal doxorubicin administration in patients with gynecologic malignancies. (Uyar D, Kulp B, Peterson G, Zanotti K, Markman M, Belinson J) Gynecol Oncol 2004 Jul;94(1):147-51 PMID: 15262133 SCOPUS ID: 2-s2.0-3242703387 07/21/2004       42 Citations
  • False positive diagnosis in conventional and liquid-based cervical specimens. (Mount S, Harmon M, Eltabbakh G, Uyar D, Leiman G) Acta Cytol 2004;48(3):363-71 PMID: 15192952 SCOPUS ID: 2-s2.0-2442680506 06/15/2004       18 Citations
  • Apoptotic pathways of epothilone BMS 310705. (Uyar D, Takigawa N, Mekhail T, Grabowski D, Markman M, Lee F, Canetta R, Peck R, Bukowski R, Ganapathi R) Gynecol Oncol 2003 Oct;91(1):173-8 PMID: 14529678 SCOPUS ID: 2-s2.0-0141757448 10/08/2003       21 Citations
  • Positive predictive value of liquid-based and conventional cervical Papanicolaou smears reported as malignant. (Uyar DS, Eltabbakh GH, Mount SL) Gynecol Oncol 2003 May;89(2):227-32 PMID: 12713984 SCOPUS ID: 2-s2.0-0037405473 04/26/2003       25 Citations
  • Integration of 28 STSs into the physical map of human chromosome 18. (Gerken S, Fish K, Uyar D, Polymeropoulos MH, Bradley P, White R, Overhauser J, Silverman GA) Genomics 1994 Dec;24(3):612-3 PMID: 7713522 SCOPUS ID: 2-s2.0-0028555321 12/01/1994       10 Citations
  • Regional localization of 56 new human chromosome 18-specific yeast artificial chromosomes. (Chang E, Luna J, Giacalone J, Uyar D, Silverman GA, Francke U) Cytogenet Cell Genet 1994;65(1-2):136-9 PMID: 8404067 SCOPUS ID: 2-s2.0-0027504464 01/01/1994       3 Citations
    • Last update: 02/23/2025