Medical College of Wisconsin
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Amy W. Hudson PhD

Amy W. Hudson PhD


Institution: Medical College of Wisconsin
Department: Microbiology and Immunology

Member of the Cancer Center

Research Experience

  • Antigen Presentation
  • Exanthema Subitum
  • Genes, MHC Class I
  • Herpesvirus 6, Human
  • Herpesvirus 7, Human
  • insulin-responsive glucose transport
  • synaptic vesicle recyling
  • viral immune evasion
  • HHV-6
  • HHV-7
  • membrane trafficking
  • Publications

  • Adoptively transferred Vγ9Vδ2 T cells show potent antitumor effects in a preclinical B cell lymphomagenesis model. (Zumwalde NA, Sharma A, Xu X, Ma S, Schneider CL, Romero-Masters JC, Hudson AW, Gendron-Fitzpatrick A, Kenney SC, Gumperz JE) JCI Insight 2017 Jul 06;2(13) PMID: 28679955 PMCID: PMC5499361 07/07/2017    
  • Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. (Sturgill ER, Malouli D, Hansen SG, Burwitz BJ, Seo S, Schneider CL, Womack JL, Verweij MC, Ventura AB, Bhusari A, Jeffries KM, Legasse AW, Axthelm MK, Hudson AW, Sacha JB, Picker LJ, Früh K) PLoS Pathog 2016 08;12(8):e1005868 PMID: 27580123 PMCID: PMC5006984 09/01/2016       8 Citations
  • Roseoloviruses and their modulation of host defenses. (Hudson AW) Curr Opin Virol 2014 Dec;9:178-87 PMID: 25462451 12/03/2014       7 Citations
  • Adaptor protein complexes AP-1 and AP-3 are required by the HHV-7 Immunoevasin U21 for rerouting of class I MHC molecules to the lysosomal compartment. (Kimpler LA, Glosson NL, Downs D, Gonyo P, May NA, Hudson AW) PLoS One 2014;9(6):e99139 PMID: 24901711 PMCID: PMC4047081 06/06/2014       2 Citations
  • Human herpesvirus 7 U21 tetramerizes to associate with class I major histocompatibility complex molecules. (May NA, Wang Q, Balbo A, Konrad SL, Buchli R, Hildebrand WH, Schuck P, Hudson AW) J Virol 2014 Mar;88(6):3298-308 PMID: 24390327 PMCID: PMC3957921 01/07/2014       7 Citations
  • Expression of CD1c enhances human invariant NKT cell activation by α-GalCer. (Fox LM, Miksanek J, May NA, Scharf L, Lockridge JL, Veerapen N, Besra GS, Adams EJ, Hudson AW, Gumperz JE) Cancer Immun 2013;13:9 PMID: 23885215 PMCID: PMC3721260 07/26/2013       7 Citations
  • The human herpesvirus-7 (HHV-7) U21 immunoevasin subverts NK-mediated cytoxicity through modulation of MICA and MICB. (Schneider CL, Hudson AW) PLoS Pathog 2011 Nov;7(11):e1002362 PMID: 22102813 PMCID: PMC3213103 11/22/2011       24 Citations
  • Insight into the mechanism of human herpesvirus 7 U21-mediated diversion of class I MHC molecules to lysosomes. (Glosson NL, Gonyo P, May NA, Schneider CL, Ristow LC, Wang Q, Hudson AW) J Biol Chem 2010 Nov 19;285(47):37016-29 PMID: 20833720 PMCID: PMC2978630 09/14/2010       10 Citations
  • Human herpesvirus 7 u21 downregulates classical and nonclassical class I major histocompatibility complex molecules from the cell surface. (May NA, Glosson NL, Hudson AW) J Virol 2010 Apr;84(8):3738-51 PMID: 20106916 PMCID: PMC2849505 01/29/2010       14 Citations
  • Human herpesvirus-6A and -6B encode viral immunoevasins that downregulate class I MHC molecules. (Glosson NL, Hudson AW) Virology 2007 Aug 15;365(1):125-35 PMID: 17467766 05/01/2007       34 Citations
  • Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein. (Cooper EM, Hudson AW, Amos J, Wagstaff J, Howley PM) J Biol Chem 2004 Sep 24;279(39):41208-17 PMID: 15263005 07/21/2004       54 Citations
  • The ER-lumenal domain of the HHV-7 immunoevasin U21 directs class I MHC molecules to lysosomes. (Hudson AW, Blom D, Howley PM, Ploegh HL) Traffic 2003 Dec;4(12):824-37 PMID: 14617346 11/18/2003       23 Citations
  • The cell biology of antigen presentation. (Hudson AW, Ploegh HL) Exp Cell Res 2002 Jan 01;272(1):1-7 PMID: 11740859 12/13/2001       27 Citations
  • A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes. (Hudson AW, Howley PM, Ploegh HL) J Virol 2001 Dec;75(24):12347-58 PMID: 11711625 PMCID: PMC116131 11/17/2001       42 Citations
  • Identification of a nonneuronal isoform of synaptotagmin. (Hudson AW, Birnbaum MJ) Proc Natl Acad Sci U S A 1995 Jun 20;92(13):5895-9 PMID: 7597049 PMCID: PMC41608 06/20/1995       72 Citations
  • Targeting of the "insulin-responsive" glucose transporter (GLUT4) to the regulated secretory pathway in PC12 cells. (Hudson AW, Fingar DC, Seidner GA, Griffiths G, Burke B, Birnbaum MJ) J Cell Biol 1993 Aug;122(3):579-88 PMID: 8335686 PMCID: PMC2119662 08/01/1993       52 Citations
  • Isoform-specific subcellular targeting of glucose transporters in mouse fibroblasts. (Hudson AW, Ruiz M, Birnbaum MJ) J Cell Biol 1992 Feb;116(3):785-97 PMID: 1309819 PMCID: PMC2289322 02/01/1992       75 Citations
  • Last update: 02/12/2019
    jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad