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Gwen Lomberk PhD

Gwen Lomberk PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Administration
Program: General

Member of the Cancer Center
Member of the Mellowes Center for Genomic Sciences and Precision Medicine

View Curriculum Vitae

Research Experience

  • Cell Cycle Proteins
  • Cell Nucleus Shape
  • Chromatin
  • Chromatin Assembly and Disassembly
  • Chromatin Immunoprecipitation
  • Chromosomal Proteins, Non-Histone
  • Epigenesis, Genetic
  • Gene Expression Regulation
  • Gene Expression Regulation, Neoplastic
  • Histone Code
  • Histone-Lysine N-Methyltransferase
  • Kruppel-Like Transcription Factors
  • Nuclear Proteins
  • Pancreatic Neoplasms

    • Leadership Positions

  • Chief, Division of Research
  • Director Basic Science Research, Department of Surgery

    • Publications (172)

  • EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas. (Pollin G, Mathison AJ, de Assuncao TM, Thomas A, Zeighami L, Salmonson A, Liu H, Urrutia G, Vankayala P, Pandol SJ, Zimmermann MT, Iovanna J, Jin VX, Urrutia R, Lomberk G) bioRxiv 2024 Mar 16 PMID: 38529489 PMCID: PMC10962735 03/26/2024    
  • Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in KrasG12D-driven tumors. (Santofimia-Castaño P, Fraunhoffer N, Liu X, Bessone IF, di Magliano MP, Audebert S, Camoin L, Estaras M, Brenière M, Modesti M, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J) EMBO Mol Med 2024 Mar;16(3):475-505 PMID: 38360999 PMCID: PMC10940650 SCOPUS ID: 2-s2.0-85185320484 02/16/2024       1 Citation
  • Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction. (Jorge SD, Chi YI, Mazaba JL, Haque N, Wagenknecht J, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) Front Genet 2023;14:1291307 PMID: 38090150 PMCID: PMC10715303 SCOPUS ID: 2-s2.0-85179362461 12/13/2023    
  • A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1. (Chi YI, Jorge SD, Jensen DR, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) Comput Struct Biotechnol J 2023;21:5249-5258 PMID: 37954151 PMCID: PMC10632586 SCOPUS ID: 2-s2.0-85174744984 11/13/2023    
  • Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape. (Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Valdivia Esparza GK, Leverence EN, Milech De Assuncao T, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT) Comput Struct Biotechnol J 2023;21:4790-4803 PMID: 37841325 PMCID: PMC10570560 SCOPUS ID: 2-s2.0-85173171942 10/16/2023    
  • A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in EHMT1. (Chi YI, Jorge SD, Jensen DR, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) bioRxiv 2023 Sep 07 PMID: 37786696 PMCID: PMC10541560 10/03/2023    
  • Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry. (Pollin G, De Assuncao TM, Doria Jorge S, Chi YI, Charlesworth MC, Madden B, Iovanna J, Zimmermann MT, Urrutia R, Lomberk G) Biosci Rep 2023 Oct 31;43(10) PMID: 37782747 PMCID: PMC10611923 SCOPUS ID: 2-s2.0-85175273435 10/02/2023    
  • Priming therapy by targeting enhancer-initiated pathways in patient-derived pancreatic cancer cells (Fraunhoffer NA, Moreno Vega AI, Abuelafia AM, Morvan M, Lebarbier E, Mary-Huard T, Zimmermann M, Lomberk G, Urrutia R, Dusetti N, Blum Y, Nicolle R, Iovanna J) eBioMedicine June 2023;92 SCOPUS ID: 2-s2.0-85154565512 06/01/2023       2 Citations
  • Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape. (Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Esparza GV, Leverence EN, De Assuncao TM, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT) bioRxiv 2023 Apr 28 PMID: 37207265 PMCID: PMC10189839 05/19/2023    
  • Priming therapy by targeting enhancer-initiated pathways in patient-derived pancreatic cancer cells. (Fraunhoffer NA, Moreno Vega AI, Abuelafia AM, Morvan M, Lebarbier E, Mary-Huard T, Zimmermann MT, Lomberk G, Urrutia R, Dusetti N, Blum Y, Nicolle R, Iovanna J) EBioMedicine 2023 Jun;92:104602 PMID: 37148583 PMCID: PMC10189188 SCOPUS ID: 2-s2.0-85154565512 05/06/2023       2 Citations
  • KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress. (Yang Y, Bhargava D, Chen X, Zhou T, Dursuk G, Jiang W, Wang J, Zong Z, Katz SI, Lomberk GA, Urrutia RA, Katz JP) Cell Death Dis 2023 May 02;14(5):299 PMID: 37130837 PMCID: PMC10154356 SCOPUS ID: 2-s2.0-85157983058 05/03/2023    
  • Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape (Ratnasinghe BD, Haque N, Wagenknecht JB, Jensen DR, Valdivia Esparza GK, Leverence EN, Milech De Assuncao T, Mathison AJ, Lomberk G, Smith BC, Volkman BF, Urrutia R, Zimmermann MT) Computational and Structural Biotechnology Journal January 2023;21:4790-4803 SCOPUS ID: 2-s2.0-85173171942 01/01/2023    
  • A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1 (Chi YI, Jorge SD, Jensen DR, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) Computational and Structural Biotechnology Journal January 2023;21:5249-5258 SCOPUS ID: 2-s2.0-85174744984 01/01/2023    
  • Multi-omics data integration and modeling unravels new mechanisms for pancreatic cancer and improves prognostic prediction (Fraunhoffer NA, Abuelafia AM, Bigonnet M, Gayet O, Roques J, Nicolle R, Lomberk G, Urrutia R, Dusetti N, Iovanna J) npj Precision Oncology December 2022;6(1) SCOPUS ID: 2-s2.0-85136999952 12/01/2022       7 Citations
  • G9a Modulates Lipid Metabolism in CD4 T Cells to Regulate Intestinal Inflammation. (Ramos GP, Bamidele AO, Klatt EE, Sagstetter MR, Kurdi AT, Hamdan FH, Kosinsky RL, Gaballa JM, Nair A, Sun Z, Dasari S, Lanza IR, Rozeveld CN, Schott MB, Urrutia G, Westphal MS, Clarkson BD, Howe CL, Marietta EV, Luckey DH, Murray JA, Gonzalez M, Braga Neto MB, Gibbons HR, Smyrk TC, Johnsen S, Lomberk G, Faubion WA) Gastroenterology 2023 Feb;164(2):256-271.e10 PMID: 36272457 PMCID: PMC9892272 SCOPUS ID: 2-s2.0-85146286897 10/23/2022       7 Citations
  • Multi-omics data integration and modeling unravels new mechanisms for pancreatic cancer and improves prognostic prediction. (Fraunhoffer NA, Abuelafia AM, Bigonnet M, Gayet O, Roques J, Nicolle R, Lomberk G, Urrutia R, Dusetti N, Iovanna J) NPJ Precis Oncol 2022 Aug 17;6(1):57 PMID: 35978026 PMCID: PMC9385633 SCOPUS ID: 2-s2.0-85136999952 08/18/2022       7 Citations
  • Precision medicine in trauma: a transformational frontier in patient care, education, and research (Davis CS, Wilkinson KH, Lin E, Carpenter NJ, Georgeades C, Lomberk G, Urrutia R) European Journal of Trauma and Emergency Surgery August 2022;48(4):2607-2612 SCOPUS ID: 2-s2.0-85119154805 08/01/2022       4 Citations
  • NUPR1 protects against hyperPARylation-dependent cell death. (Santofimia-Castaño P, Huang C, Liu X, Xia Y, Audebert S, Camoin L, Peng L, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J) Commun Biol 2022 Jul 22;5(1):732 PMID: 35869257 PMCID: PMC9307593 SCOPUS ID: 2-s2.0-85134559984 07/23/2022       5 Citations
  • Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers. (Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) Comput Struct Biotechnol J 2022;20:2200-2211 PMID: 35615018 PMCID: PMC9111933 SCOPUS ID: 2-s2.0-85130080827 05/27/2022       4 Citations
  • To ChIP, or to CUT, that is the question: Comparative Evaluation of NextGen Methodologies for Studying the genome-wide distribution of Histone H3 Lysine 9 di-methyl mark in pancreatic cells. (Urrutia G, Abrudan JL, Du M, de Assuncao TM, Mathison AJ, Zimmermann MT, Lomberk G, Urrutia R) FASEB J 2022 May;36 Suppl 1 PMID: 35556470 SCOPUS ID: 2-s2.0-85130072518 05/14/2022    
  • Transcriptional Landscape Established by the Euchromatic Histone-lysine N-methyltransferase Pathway During Pancreas Ontogenesis and Pancreatitis. (Urrutia R, Salmonson A, Urrutia G, de Assuncao TM, Zimmermann MT, Mathison AJ, Lomberk G) FASEB J 2022 May;36 Suppl 1 PMID: 35556469 SCOPUS ID: 2-s2.0-85130010001 05/14/2022    
  • Defining the Mutational Landscape That Affects the Histone Demethylase KDM6A/UTX in Human Cancer. (Chi YI, Stodola TJ, de Assuncao TM, Volkman B, Smith B, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R) FASEB J 2022 May;36 Suppl 1 PMID: 35555661 SCOPUS ID: 2-s2.0-85130046941 05/14/2022    
  • Epigenomic mechanisms used by KrasG12D to regulate inflammatory gene clusters in epithelial pancreatic cancer cells, which are critical for reprogramming the tumor microenvironment. (Du M, Abrudan JL, Urrutia G, de Assuncao TM, Mathison AJ, Zimmermann MT, Lomberk G, Urrutia R) FASEB J 2022 May;36 Suppl 1 PMID: 35552230 SCOPUS ID: 2-s2.0-85130057842 05/14/2022    
  • Functional Inferences Derived from Defining the Interactome of H3K9me2 Writers and Readers (Pollin G, de Assuncao TM, Lomberk G, Urrutia R) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1 May 2022;36 PMID: 35552325 SCOPUS ID: 2-s2.0-85130026676 05/01/2022    
  • G9a Responds to KRAS-Mediated Replication Stress by Increased Origin Licensing (Thomas A, Milech de Assuncao T, Lomberk G) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1 May 2022;36 PMID: 35560683 SCOPUS ID: 2-s2.0-85130020107 05/01/2022    
  • Adapting Mentoring in Times of Crisis: What We Learned from COVID-19. (Tetzlaff J, Lomberk G, Smith HM, Agrawal H, Siegel DH, Apps JN) Acad Psychiatry 2022 Dec;46(6):774-779 PMID: 35217939 PMCID: PMC8880296 SCOPUS ID: 2-s2.0-85125902024 02/27/2022       5 Citations
  • Collateral Victim or Rescue Worker?-The Role of Histone Methyltransferases in DNA Damage Repair and Their Targeting for Therapeutic Opportunities in Cancer. (He L, Lomberk G) Front Cell Dev Biol 2021;9:735107 PMID: 34869318 PMCID: PMC8636273 SCOPUS ID: 2-s2.0-85120731755 12/07/2021       1 Citation
  • Precision medicine in trauma: a transformational frontier in patient care, education, and research. (Davis CS, Wilkinson KH, Lin E, Carpenter NJ, Georgeades C, Lomberk G, Urrutia R) Eur J Trauma Emerg Surg 2022 Aug;48(4):2607-2612 PMID: 34786598 PMCID: PMC8594650 SCOPUS ID: 2-s2.0-85119154805 11/18/2021       4 Citations
  • Collateral Victim or Rescue Worker?—The Role of Histone Methyltransferases in DNA Damage Repair and Their Targeting for Therapeutic Opportunities in Cancer (He L, Lomberk G) Frontiers in Cell and Developmental Biology 16 November 2021;9 SCOPUS ID: 2-s2.0-85120731755 11/16/2021       1 Citation
  • KrasG12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells. (Mathison AJ, Kerketta R, de Assuncao TM, Leverence E, Zeighami A, Urrutia G, Stodola TJ, di Magliano MP, Iovanna JL, Zimmermann MT, Lomberk G, Urrutia R) Genome Biol 2021 Oct 14;22(1):289 PMID: 34649604 PMCID: PMC8518179 SCOPUS ID: 2-s2.0-85117299300 10/16/2021       5 Citations
  • Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis. (Stodola TJ, Chi YI, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R) Proteins 2022 Jan;90(1):282-298 PMID: 34414607 PMCID: PMC8671179 SCOPUS ID: 2-s2.0-85114677469 08/21/2021       2 Citations
  • Effects of Subnormothermic Regulated Hepatic Reperfusion on Mitochondrial and Transcriptomic Profiles in a Porcine Model. (Kim J, Zimmerman MA, Shin WY, Boettcher BT, Lee JS, Park JI, Ali M, Yang M, Mishra J, Hagen CE, McGraw JE, Mathison A, Woehlck HJ, Lomberk G, Camara AKS, Urrutia RA, Stowe DF, Hong JC) Ann Surg 2023 Feb 01;277(2):e366-e375 PMID: 34387201 PMCID: PMC8840998 SCOPUS ID: 2-s2.0-85146161896 08/14/2021       7 Citations
  • Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks. (Urrutia G, de Assuncao TM, Mathison AJ, Salmonson A, Kerketta R, Zeighami A, Stodola TJ, Adsay V, Pehlivanoglu B, Dwinell MB, Zimmermann MT, Iovanna JL, Urrutia R, Lomberk G) Front Cell Dev Biol 2021;9:681153 PMID: 34249932 PMCID: PMC8261250 SCOPUS ID: 2-s2.0-85116952280 07/13/2021       4 Citations
  • New Insights Into Pancreatic Cancer: Notes from a Virtual Meeting. (Hessmann E, Schneider G, 1(st) Virtual Göttingen-Munich-Marburg Pancreatic Cancer Meeting) Gastroenterology 2021 Sep;161(3):785-791 PMID: 34089734 SCOPUS ID: 2-s2.0-85112794735 06/06/2021       3 Citations
  • Correction to: Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction. (Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Basel DG, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R) Orphanet J Rare Dis 2021 Jun 01;16(1):247 PMID: 34074320 PMCID: PMC8170813 SCOPUS ID: 2-s2.0-85107273180 06/03/2021    
  • Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer. (Cano CE, José Sandí M, Hamidi T, Calvo EL, Turrini O, Bartholin L, Loncle C, Secq V, Garcia S, Lomberk G, Kroemer G, Urrutia R, Iovanna JL) EMBO Mol Med 2021 May 07;13(5):e14243 PMID: 33960146 PMCID: PMC8103076 SCOPUS ID: 2-s2.0-85105133639 05/08/2021       1 Citation
  • Corrigendum to: Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer (EMBO Molecular Medicine, (2012), 4, 9, (964-979), 10.1002/emmm.201201255) (Cano CE, José Sandí M, Hamidi T, Calvo EL, Turrini O, Bartholin L, Loncle C, Secq V, Garcia S, Lomberk G, Kroemer G, Urrutia R, Iovanna JL) EMBO Molecular Medicine 7 May 2021;13(5) SCOPUS ID: 2-s2.0-85105133639 05/07/2021       1 Citation
  • Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance. (Kaoutari AE, Fraunhoffer NA, Hoare O, Teyssedou C, Soubeyran P, Gayet O, Roques J, Lomberk G, Urrutia R, Dusetti N, Iovanna J) EBioMedicine 2021 Apr;66:103332 PMID: 33862584 PMCID: PMC8054161 SCOPUS ID: 2-s2.0-85104049834 04/17/2021       23 Citations
  • A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer. (Kloesch B, Ionasz V, Paliwal S, Hruschka N, Martinez de Villarreal J, Öllinger R, Mueller S, Dienes HP, Schindl M, Gruber ES, Stift J, Herndler-Brandstetter D, Lomberk GA, Seidler B, Saur D, Rad R, Urrutia RA, Real FX, Martinelli P) Gut 2022 Apr;71(4):766-777 PMID: 33846140 PMCID: PMC9733634 SCOPUS ID: 2-s2.0-85104197617 04/14/2021       37 Citations
  • Interpreting Sequence Variation in PDAC-Predisposing Genes Using a Multi-Tier Annotation Approach Performed at the Gene, Patient, and Cohort Level. (Zimmermann MT, Mathison AJ, Stodola T, Evans DB, Abrudan JL, Demos W, Tschannen M, Aldakkak M, Geurts J, Lomberk G, Tsai S, Urrutia R) Front Oncol 2021;11:606820 PMID: 33747920 PMCID: PMC7973372 SCOPUS ID: 2-s2.0-85102941394 03/23/2021       4 Citations
  • Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells. (Wang Y, Wu J, Chen H, Yang Y, Xiao C, Yi X, Shi C, Zhong K, He H, Li Y, Wu Z, Zhou G, Rao Q, Wang X, Zhou X, Lomberk G, Liu B, Zhao J, Ge J, Zhou W, Chu X, Chen C, Zhou X, Wang L, Guan K, Qu L) Sci Adv 2021 Jan;7(5) PMID: 33571129 PMCID: PMC7840125 SCOPUS ID: 2-s2.0-85099945962 02/12/2021       22 Citations
  • Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction. (Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Basel DG, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R) Orphanet J Rare Dis 2021 Feb 05;16(1):66 PMID: 33546721 PMCID: PMC7866879 SCOPUS ID: 2-s2.0-85100579633 02/07/2021       11 Citations
  • Genome-wide CRISPR-Cas9 screen identified KLF11 as a druggable suppressor for sarcoma cancer stem cells (Wang Y, Wu J, Chen H, Yang Y, Xiao C, Yi X, Shi C, Zhong K, He H, Li Y, Wu Z, Zhou G, Rao Q, Wang X, Zhou X, Lomberk G, Liu B, Zhao J, Ge J, Zhou W, Chu X, Chen C, Zhou X, Wang L, Guan K, Qu L) Science Advances 27 January 2021;7(5) SCOPUS ID: 2-s2.0-85099945962 01/27/2021       22 Citations
  • ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents. (Lan W, Santofimia-Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S, Camoin L, Huang C, Peng L, Jiménez-Alesanco A, Velázquez-Campoy A, Abián O, Lomberk G, Urrutia R, Rizzuti B, Geli V, Soubeyran P, Neira JL, Iovanna J) JCI Insight 2020 Sep 17;5(18) PMID: 32780723 PMCID: PMC7526551 SCOPUS ID: 2-s2.0-85090785767 08/12/2020       26 Citations
  • Variant anatomy of the biliary system as a cause of pancreatic and peri-ampullary cancers. (Muraki T, Reid MD, Pehlivanoglu B, Gonzalez RS, Sekhar A, Memis B, Xue Y, Cheng J, Jang KT, Mittal P, Cardona K, Kooby DA, Maithel S, Sarmiento JM, El-Rayes B, Lomberk G, Urrutia RA, Christians K, Tsai S, Evans DB, Adsay V) HPB (Oxford) 2020 Dec;22(12):1675-1685 PMID: 32336556 SCOPUS ID: 2-s2.0-85083637358 04/28/2020       10 Citations
  • Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain. (Mathison A, Milech De Assuncao T, Dsouza NR, Williams M, Zimmermann MT, Urrutia R, Lomberk G) PLoS One 2020;15(2):e0217452 PMID: 32027651 PMCID: PMC7004349 SCOPUS ID: 2-s2.0-85079081692 02/07/2020       4 Citations
  • Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse. (Urrutia G, Salmonson A, Toro-Zapata J, de Assuncao TM, Mathison A, Dusetti N, Iovanna J, Urrutia R, Lomberk G) Mol Cancer Res 2020 Mar;18(3):448-462 PMID: 31822519 PMCID: PMC7056528 SCOPUS ID: 2-s2.0-85081130002 12/12/2019       10 Citations
  • Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma. (Santofimia-Castaño P, Xia Y, Peng L, Velázquez-Campoy A, Abián O, Lan W, Lomberk G, Urrutia R, Rizzuti B, Soubeyran P, Neira JL, Iovanna J) Cells 2019 Nov 17;8(11) PMID: 31744261 PMCID: PMC6912534 SCOPUS ID: 2-s2.0-85082729502 11/21/2019       30 Citations
  • Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine. (Lomberk G, Dusetti N, Iovanna J, Urrutia R) Nat Commun 2019 Aug 28;10(1):3875 PMID: 31462645 PMCID: PMC6713756 SCOPUS ID: 2-s2.0-85071625821 08/30/2019       57 Citations
  • Modeling post-translational modifications and cancer-associated mutations that impact the heterochromatin protein 1α-importin α heterodimers. (Zimmermann MT, Williams MM, Klee EW, Lomberk GA, Urrutia R) Proteins 2019 Nov;87(11):904-916 PMID: 31152607 PMCID: PMC6790107 SCOPUS ID: 2-s2.0-85067403924 06/04/2019       4 Citations
  • Aurora kinase B-phosphorylated HP1α functions in chromosomal instability. (Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA) Cell Cycle 2019 Jun;18(12):1407-1421 PMID: 31130069 PMCID: PMC6592258 SCOPUS ID: 2-s2.0-85067316375 05/28/2019       7 Citations
  • CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis. (Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ) JCI Insight 2019 May 16;5(12) PMID: 31095524 PMCID: PMC6629126 SCOPUS ID: 2-s2.0-85070659965 05/17/2019       52 Citations
  • The New Bench for the Academic Surgeon: Precision Medicine (Lomberk G, Urrutia R) Management of Localized Pancreatic Cancer: Current Treatment and Challenges 1 January 2019:187-198 SCOPUS ID: 2-s2.0-85150138867 01/01/2019    
  • Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. (Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH) Cell Mol Gastroenterol Hepatol 2019;7(1):197-209 PMID: 30539787 PMCID: PMC6282644 SCOPUS ID: 2-s2.0-85057853914 12/13/2018       51 Citations
  • Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. (Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA Jr) Cell Mol Gastroenterol Hepatol 2019;7(1):55-71 PMID: 30510991 PMCID: PMC6260395 SCOPUS ID: 2-s2.0-85056879256 12/05/2018       23 Citations
  • Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis. (Santofimia-Castaño P, Lan W, Bintz J, Gayet O, Carrier A, Lomberk G, Neira JL, González A, Urrutia R, Soubeyran P, Iovanna J) Sci Rep 2018 Nov 19;8(1):16999 PMID: 30451898 PMCID: PMC6242935 SCOPUS ID: 2-s2.0-85056700597 11/20/2018       43 Citations
  • Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway. (Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R) Sci Rep 2018 Oct 10;8(1):15077 PMID: 30305677 PMCID: PMC6180112 SCOPUS ID: 2-s2.0-85054625299 10/12/2018       4 Citations
  • Epigenetics of gastrointestinal diseases: notes from a workshop. (Marks DL, Olson RL, Urrutia R, Billadeau DD, Roy N, Calin GA, Fabbri M, Koutsioumpa M, Iliopoulos D, Ordog T, Huebert R, Sarmento O, Bamidele AO, Faubion W, Lomberk GL, Siveke J, Ahuja N, Iovanna J, Hlady RA, Robertson K, Kisiel J, Pin CL, Fernandez-Zapico ME) Epigenetics 2018;13(4):449-457 PMID: 30056798 PMCID: PMC6140811 SCOPUS ID: 2-s2.0-85052053592 07/31/2018       2 Citations
  • Co-occurrence of a maternally inherited DNMT3A duplication and a paternally inherited pathogenic variant in EZH2 in a child with growth retardation and severe short stature: atypical Weaver syndrome or evidence of a DNMT3A dosage effect? (Polonis K, Blackburn PR, Urrutia RA, Lomberk GA, Kruisselbrink T, Cousin MA, Boczek NJ, Hoppman NL, Babovic-Vuksanovic D, Klee EW, Pichurin PN) Cold Spring Harb Mol Case Stud 2018 Aug;4(4) PMID: 29802153 PMCID: PMC6071565 SCOPUS ID: 2-s2.0-85054778837 05/29/2018       7 Citations
  • Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes. (Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R) Nat Commun 2018 May 17;9(1):1978 PMID: 29773832 PMCID: PMC5958058 SCOPUS ID: 2-s2.0-85047248746 05/19/2018       157 Citations
  • Notch signaling in pancreatic morphogenesis and pancreatic cancer pathogenesis (Lomberk G, Urrutia R) Pancreatic Cancer 11 April 2018:457-479 SCOPUS ID: 2-s2.0-85054047066 04/11/2018    
  • Epigenetics and its applications to the progression model of pancreatic cancer (Lomberk G, Urrutia R) Pancreatic Cancer 11 April 2018:177-208 SCOPUS ID: 2-s2.0-85054045572 04/11/2018    
  • EGFR (ErbB) signaling pathways in pancreatic cancer pathogenesis (Williams M, Lomberk G, Urrutia R) Pancreatic Cancer 11 April 2018:383-408 SCOPUS ID: 2-s2.0-85054048146 04/11/2018       2 Citations
  • Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. (Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH) JCI Insight 2017 Dec 21;2(24) PMID: 29263300 PMCID: PMC5752303 SCOPUS ID: 2-s2.0-85050938173 12/22/2017       17 Citations
  • LSD1, a double-edged sword, confers dynamic chromatin regulation but commonly promotes aberrant cell growth. (Kozub MM, Carr RM, Lomberk GL, Fernandez-Zapico ME) F1000Res 2017;6:2016 PMID: 29225781 PMCID: PMC5691370 SCOPUS ID: 2-s2.0-85034565397 12/12/2017       25 Citations
  • Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts. (Nicolle R, Blum Y, Marisa L, Loncle C, Gayet O, Moutardier V, Turrini O, Giovannini M, Bian B, Bigonnet M, Rubis M, Elarouci N, Armenoult L, Ayadi M, Duconseil P, Gasmi M, Ouaissi M, Maignan A, Lomberk G, Boher JM, Ewald J, Bories E, Garnier J, Goncalves A, Poizat F, Raoul JL, Secq V, Garcia S, Grandval P, Barraud-Blanc M, Norguet E, Gilabert M, Delpero JR, Roques J, Calvo E, Guillaumond F, Vasseur S, Urrutia R, de Reyniès A, Dusetti N, Iovanna J) Cell Rep 2017 Nov 28;21(9):2458-2470 PMID: 29186684 PMCID: PMC6082139 SCOPUS ID: 2-s2.0-85035748327 12/01/2017       135 Citations
  • Resolution of Cochlear Inflammation: Novel Target for Preventing or Ameliorating Drug-, Noise- and Age-related Hearing Loss. (Kalinec GM, Lomberk G, Urrutia RA, Kalinec F) Front Cell Neurosci 2017;11:192 PMID: 28736517 PMCID: PMC5500902 SCOPUS ID: 2-s2.0-85026658590 07/25/2017       85 Citations
  • Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling. (Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW) Cold Spring Harb Mol Case Stud 2017 Jul;3(4) PMID: 28679693 PMCID: PMC5495030 SCOPUS ID: 2-s2.0-85037598912 07/07/2017       7 Citations
  • Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe. (Mathison A, Salmonson A, Missfeldt M, Bintz J, Williams M, Kossak S, Nair A, de Assuncao TM, Christensen T, Buttar N, Iovanna J, Huebert R, Lomberk G) Mol Cancer Res 2017 Aug;15(8):984-997 PMID: 28442587 PMCID: PMC5705946 SCOPUS ID: 2-s2.0-85026643394 04/27/2017       16 Citations
  • A novel de novo frameshift deletion in EHMT1 in a patient with Kleefstra Syndrome results in decreased H3K9 dimethylation. (Blackburn PR, Williams M, Cousin MA, Boczek NJ, Beek GJ, Lomberk GA, Urrutia RA, Babovic-Vuksanovic D, Klee EW) Mol Genet Genomic Med 2017 Mar;5(2):141-146 PMID: 28361100 PMCID: PMC5370226 SCOPUS ID: 2-s2.0-85041429164 04/01/2017       7 Citations
  • Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts. (Bian B, Bigonnet M, Gayet O, Loncle C, Maignan A, Gilabert M, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, Poizat F, Nicolle R, Blum Y, Marisa L, Rubis M, Raoul JL, Bradner JE, Qi J, Lomberk G, Urrutia R, Saul A, Dusetti N, Iovanna J) EMBO Mol Med 2017 Apr;9(4):482-497 PMID: 28275007 PMCID: PMC5376755 SCOPUS ID: 2-s2.0-85014779112 03/10/2017       58 Citations
  • A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding. (Blackburn PR, Tischer A, Zimmermann MT, Kemppainen JL, Sastry S, Knight Johnson AE, Cousin MA, Boczek NJ, Oliver G, Misra VK, Gavrilova RH, Lomberk G, Auton M, Urrutia R, Klee EW) J Biol Chem 2017 Mar 03;292(9):3866-3876 PMID: 28057753 PMCID: PMC5339767 SCOPUS ID: 2-s2.0-85014566714 01/07/2017       15 Citations
  • Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion. (Jalan-Sakrikar N, De Assuncao TM, Lu J, Almada LL, Lomberk G, Fernandez-Zapico ME, Urrutia R, Huebert RC) PLoS One 2016;11(12):e0168266 PMID: 27936185 PMCID: PMC5148157 SCOPUS ID: 2-s2.0-85005949179 12/10/2016       14 Citations
  • Pharmacological and Therapeutic Targeting of Epigenetic Regulators (Urrutia R, Lomberk GA) Chromatin Signaling and Diseases 24 August 2016:387-401 SCOPUS ID: 2-s2.0-85018796379 08/24/2016    
  • The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation. (Loncle C, Molejon MI, Lac S, Tellechea JI, Lomberk G, Gramatica L, Fernandez Zapico MF, Dusetti N, Urrutia R, Iovanna JL) Cell Death Dis 2016 Jul 14;7(7):e2295 PMID: 27415425 PMCID: PMC4973346 SCOPUS ID: 2-s2.0-85016946884 07/16/2016       26 Citations
  • The promise of epigenomic therapeutics in pancreatic cancer. (Lomberk GA, Iovanna J, Urrutia R) Epigenomics 2016 Jun;8(6):831-42 PMID: 27337224 PMCID: PMC5066125 SCOPUS ID: 2-s2.0-84978187321 06/24/2016       38 Citations
  • REG3β Plays a Key Role in IL17RA Protumoral Effect-Response. (Loncle C, Bonjoch L, Folch-Puy E, Lopez-Millan MB, Lac S, Molejon MI, Chuluyan E, Cordelier P, Dubus P, Lomberk G, Urrutia R, Closa D, Iovanna JL) Cancer Res 2016 Apr 01;76(7):2051 PMID: 26992425 SCOPUS ID: 2-s2.0-84963755978 03/20/2016       5 Citations
  • Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ. (Velez G, Lin M, Christensen T, Faubion WA, Lomberk G, Urrutia R) J Mol Model 2016 Jan;22(1):12 PMID: 26680990 PMCID: PMC4683166 SCOPUS ID: 2-s2.0-84950318764 12/19/2015       13 Citations
  • Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation. (Grasso D, Bintz J, Lomberk G, Molejon MI, Loncle C, Garcia MN, Lopez MB, Urrutia R, Iovanna JL) Sci Rep 2015 Nov 30;5:17549 PMID: 26617245 PMCID: PMC4663475 SCOPUS ID: 2-s2.0-84948695230 12/01/2015       25 Citations
  • Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation. (Papadakis KA, Krempski J, Svingen P, Xiong Y, Sarmento OF, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Gastrointest Liver Physiol 2015 Dec 01;309(11):G900-9 PMID: 26472224 PMCID: PMC4669350 SCOPUS ID: 2-s2.0-84949188711 10/17/2015       19 Citations
  • Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. (De Assuncao TM, Sun Y, Jalan-Sakrikar N, Drinane MC, Huang BQ, Li Y, Davila JI, Wang R, O'Hara SP, Lomberk GA, Urrutia RA, Ikeda Y, Huebert RC) Lab Invest 2015 Oct;95(10):1218 PMID: 26412498 SCOPUS ID: 2-s2.0-84942766325 09/29/2015       5 Citations
  • IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer. (Loncle C, Bonjoch L, Folch-Puy E, Lopez-Millan MB, Lac S, Molejon MI, Chuluyan E, Cordelier P, Dubus P, Lomberk G, Urrutia R, Closa D, Iovanna JL) Cancer Res 2015 Nov 15;75(22):4852-62 PMID: 26404002 PMCID: PMC4651828 SCOPUS ID: 2-s2.0-84955115797 09/26/2015       88 Citations
  • Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. (Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE) J Clin Invest 2015 Oct 01;125(10):3819-30 PMID: 26368306 PMCID: PMC4607137 SCOPUS ID: 2-s2.0-84943222952 09/15/2015       62 Citations
  • The Triple-Code Model for Pancreatic Cancer: Cross Talk Among Genetics, Epigenetics, and Nuclear Structure. (Lomberk GA, Urrutia R) Surg Clin North Am 2015 Oct;95(5):935-52 PMID: 26315515 PMCID: PMC4556141 SCOPUS ID: 2-s2.0-84940614230 09/01/2015       18 Citations
  • Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes. (Mathison A, Escande C, Calvo E, Seo S, White T, Salmonson A, Faubion WA Jr, Buttar N, Iovanna J, Lomberk G, Chini EN, Urrutia R) Endocrinology 2015 Oct;156(10):3581-95 PMID: 26248217 PMCID: PMC4588811 SCOPUS ID: 2-s2.0-84943616432 08/08/2015       10 Citations
  • Restoration of epigenetically silenced SULF1 expression by 5-aza-2-deoxycytidine sensitizes hepatocellular carcinoma cells to chemotherapy-induced apoptosis. (Shire A, Lomberk G, Lai JP, Zou H, Tsuchiya N, Aderca I, Moser CD, Gulaid KH, Oseini A, Hu C, Warsame O, Jenkins RB, Roberts LR) Med Epigenet 2015;3(1):1-18 PMID: 26236329 PMCID: PMC4520440 08/04/2015    
  • The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage. (Leonard PH, Grzenda A, Mathison A, Morbeck DE, Fredrickson JR, de Assuncao TM, Christensen T, Salisbury J, Calvo E, Iovanna J, Coddington CC, Urrutia R, Lomberk G) BMC Dev Biol 2015 May 29;15:23 PMID: 26021315 PMCID: PMC4448908 SCOPUS ID: 2-s2.0-84930204241 05/30/2015       6 Citations
  • Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1. (Lopez MB, Garcia MN, Grasso D, Bintz J, Molejon MI, Velez G, Lomberk G, Neira JL, Urrutia R, Iovanna J) J Cell Physiol 2015 Dec;230(12):2936-50 PMID: 25899918 PMCID: PMC4778741 SCOPUS ID: 2-s2.0-84939839118 04/23/2015       13 Citations
  • Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. (De Assuncao TM, Sun Y, Jalan-Sakrikar N, Drinane MC, Huang BQ, Li Y, Davila JI, Wang R, O'Hara SP, Lomberk GA, Urrutia RA, Ikeda Y, Huebert RC) Lab Invest 2015 Jun;95(6):684-96 PMID: 25867762 PMCID: PMC4447567 SCOPUS ID: 2-s2.0-84929851353 04/14/2015       64 Citations
  • Evidence revealing deregulation of the KLF11-MAO A pathway in association with chronic stress and depressive disorders. (Harris S, Johnson S, Duncan JW, Udemgba C, Meyer JH, Albert PR, Lomberk G, Urrutia R, Ou XM, Stockmeier CA, Wang JM) Neuropsychopharmacology 2015 May;40(6):1373-82 PMID: 25502632 PMCID: PMC4397395 SCOPUS ID: 2-s2.0-84939985471 12/17/2014       31 Citations
  • Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes. (Papadakis KA, Krempski J, Reiter J, Svingen P, Xiong Y, Sarmento OF, Huseby A, Johnson AJ, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Cell Physiol 2015 Mar 01;308(5):C362-71 PMID: 25472963 PMCID: PMC4346734 SCOPUS ID: 2-s2.0-84923870639 12/05/2014       23 Citations
  • IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation. (Garcia MN, Grasso D, Lopez-Millan MB, Hamidi T, Loncle C, Tomasini R, Lomberk G, Porteu F, Urrutia R, Iovanna JL) J Clin Invest 2014 Nov;124(11):4709-22 PMID: 25250570 PMCID: PMC4347237 SCOPUS ID: 2-s2.0-84908609029 09/25/2014       32 Citations
  • Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins. (Urrutia R, Velez G, Lin M, Lomberk G, Neira JL, Iovanna J) J Mol Model 2014 Aug;20(8):2357 PMID: 25056123 PMCID: PMC4139591 SCOPUS ID: 2-s2.0-84904525832 07/25/2014       17 Citations
  • Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. (Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA Jr) Am J Physiol Regul Integr Comp Physiol 2014 Sep 15;307(6):R608-20 PMID: 24944246 PMCID: PMC4166759 SCOPUS ID: 2-s2.0-84907147778 06/20/2014       24 Citations
  • Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence. (Grasso D, Garcia MN, Hamidi T, Cano C, Calvo E, Lomberk G, Urrutia R, Iovanna JL) Cell Death Differ 2014 Oct;21(10):1633-41 PMID: 24902898 PMCID: PMC4158688 SCOPUS ID: 2-s2.0-84939779108 06/07/2014       40 Citations
  • Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks. (Calvo E, Grzenda A, Lomberk G, Mathison A, Iovanna J, Urrutia R) BMC Mol Biol 2014 May 25;15:10 PMID: 24885560 PMCID: PMC4049485 SCOPUS ID: 2-s2.0-84902078010 06/03/2014       6 Citations
  • Aurora-A mitotic kinase induces endocrine resistance through down-regulation of ERα expression in initially ERα+ breast cancer cells. (Opyrchal M, Salisbury JL, Zhang S, McCubrey J, Hawse J, Goetz MP, Lomberk GA, Haddad T, Degnim A, Lange C, Ingle JN, Galanis E, D'Assoro AB) PLoS One 2014;9(5):e96995 PMID: 24816249 PMCID: PMC4016211 SCOPUS ID: 2-s2.0-84901235407 05/13/2014       28 Citations
  • New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. (de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH) J Biol Chem 2014 May 30;289(22):15798-809 PMID: 24759103 PMCID: PMC4140934 SCOPUS ID: 2-s2.0-84901702509 04/25/2014       42 Citations
  • Diabetes-causing gene, kruppel-like factor 11, modulates the antinociceptive response of chronic ethanol intake. (Ou XM, Udemgba C, Wang N, Dai X, Lomberk G, Seo S, Urrutia R, Wang J, Duncan J, Harris S, Fairbanks CA, Zhang X) Alcohol Clin Exp Res 2014 Feb;38(2):401-8 PMID: 24428663 PMCID: PMC5567722 SCOPUS ID: 2-s2.0-84893649158 01/17/2014       4 Citations
  • Pancreatitis promotes oncogenic Kras(G12D)-induced pancreatic transformation through activation of Nupr1. (Grasso D, Garcia MN, Hamidi T, Cano C, Calvo E, Lomberk G, Urrutia R, Iovanna JL) Mol Cell Oncol 2014;1(1):e29913 PMID: 27308320 PMCID: PMC4905183 SCOPUS ID: 2-s2.0-85051828809 01/01/2014       4 Citations
  • Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways. (Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, Ordog T) PLoS One 2013;8(10):e76822 PMID: 24116170 PMCID: PMC3792098 SCOPUS ID: 2-s2.0-84885041041 10/12/2013       13 Citations
  • Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis. (Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R) PLoS One 2013;8(9):e75311 PMID: 24069400 PMCID: PMC3775729 SCOPUS ID: 2-s2.0-84884265835 09/27/2013       23 Citations
  • Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis. (Cano CE, Hamidi T, Garcia MN, Grasso D, Loncle C, Garcia S, Calvo E, Lomberk G, Dusetti N, Bartholin L, Urrutia R, Iovanna JL) Gut 2014 Jun;63(6):984-95 PMID: 24026351 SCOPUS ID: 2-s2.0-84899917831 09/13/2013       34 Citations
  • Corrigendum to "Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis" [Cancer Lett. 328 (2) (2012) 212-221] (McCleary-Wheeler AL, Lomberk GA, Weiss FU, Schneider G, Fabbri M, Poshusta TL, Dusetti NJ, Baumgart S, Iovanna JL, Ellenrieder V, Urrutia R, Fernandez-Zapico ME) Cancer Letters 28 August 2013;337(1):143-144 SCOPUS ID: 2-s2.0-84880046000 08/28/2013    
  • Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression. (Grzenda A, Leonard P, Seo S, Mathison AJ, Urrutia G, Calvo E, Iovanna J, Urrutia R, Lomberk G) Epigenetics Chromatin 2013 Jul 05;6(1):21 PMID: 23829974 PMCID: PMC3707784 SCOPUS ID: 2-s2.0-84879835428 07/09/2013       18 Citations
  • Epigenetics: a promising paradigm for better understanding and managing pain. (Seo S, Grzenda A, Lomberk G, Ou XM, Cruciani RA, Urrutia R) J Pain 2013 Jun;14(6):549-57 PMID: 23602266 PMCID: PMC3672350 SCOPUS ID: 2-s2.0-84878347814 04/23/2013       22 Citations
  • Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young. (Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R) J Biol Chem 2013 Jun 14;288(24):17745-58 PMID: 23589285 PMCID: PMC3682574 SCOPUS ID: 2-s2.0-84879068306 04/17/2013       24 Citations
  • A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis. (Daftary GS, Zheng Y, Tabbaa ZM, Schoolmeester JK, Gada RP, Grzenda AL, Mathison AJ, Keeney GL, Lomberk GA, Urrutia R) PLoS One 2013;8(3):e60165 PMID: 23555910 PMCID: PMC3610699 SCOPUS ID: 2-s2.0-84875516286 04/05/2013       38 Citations
  • Novel role of VMP1 as modifier of the pancreatic tumor cell response to chemotherapeutic drugs. (Gilabert M, Vaccaro MI, Fernandez-Zapico ME, Calvo EL, Turrini O, Secq V, Garcia S, Moutardier V, Lomberk G, Dusetti N, Urrutia R, Iovanna JL) J Cell Physiol 2013 Sep;228(9):1834-43 PMID: 23460482 PMCID: PMC4048029 SCOPUS ID: 2-s2.0-84878217099 03/06/2013       12 Citations
  • Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression. (Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, Xiong Y, Faubion W, Urrutia R) Epigenetics Chromatin 2013 Feb 28;6(1):3 PMID: 23448518 PMCID: PMC3606351 SCOPUS ID: 2-s2.0-84874345376 03/02/2013       25 Citations
  • Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis. (McCleary-Wheeler AL, Lomberk GA, Weiss FU, Schneider G, Fabbri M, Poshusta TL, Dusetti NJ, Baumgart S, Iovanna JL, Ellenrieder V, Urrutia R, Fernandez-Zapico ME) Cancer Lett 2013 Jan 28;328(2):212-21 PMID: 23073473 PMCID: PMC3513548 SCOPUS ID: 2-s2.0-84870342265 10/18/2012       64 Citations
  • NUPR1 works against the metabolic stress-induced autophagy-associated cell death in pancreatic cancer cells. (Hamidi T, Cano CE, Grasso D, Garcia MN, Sandi MJ, Calvo EL, Dagorn JC, Lomberk G, Goruppi S, Urrutia R, Carracedo A, Velasco G, Iovanna JL) Autophagy 2013 Jan;9(1):95-7 PMID: 23047430 PMCID: PMC3542222 SCOPUS ID: 2-s2.0-84872203457 10/11/2012       22 Citations
  • Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. (Hamidi T, Cano CE, Grasso D, Garcia MN, Sandi MJ, Calvo EL, Dagorn JC, Lomberk G, Urrutia R, Goruppi S, Carracedo A, Velasco G, Iovanna JL) Clin Cancer Res 2012 Oct 01;18(19):5234-46 PMID: 22899799 SCOPUS ID: 2-s2.0-84866931110 08/18/2012       61 Citations
  • Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner. (Xiong Y, Khanna S, Grzenda AL, Sarmento OF, Svingen PA, Lomberk GA, Urrutia RA, Faubion WA Jr) J Biol Chem 2012 Oct 05;287(41):34372-85 PMID: 22896699 PMCID: PMC3464543 SCOPUS ID: 2-s2.0-84867266681 08/17/2012       53 Citations
  • Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer. (Cano CE, Sandí MJ, Hamidi T, Calvo EL, Turrini O, Bartholin L, Loncle C, Secq V, Garcia S, Lomberk G, Kroemer G, Urrutia R, Iovanna JL) EMBO Mol Med 2012 Sep;4(9):964-79 PMID: 22821859 PMCID: PMC3491828 SCOPUS ID: 2-s2.0-84863201071 07/24/2012       63 Citations
  • Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts. (Kitange GJ, Mladek AC, Carlson BL, Schroeder MA, Pokorny JL, Cen L, Decker PA, Wu W, Lomberk GA, Gupta SK, Urrutia RA, Sarkaria JN) Clin Cancer Res 2012 Aug 01;18(15):4070-9 PMID: 22675172 PMCID: PMC3716364 SCOPUS ID: 2-s2.0-84864495476 06/08/2012       116 Citations
  • Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression. (Grunewald M, Johnson S, Lu D, Wang Z, Lomberk G, Albert PR, Stockmeier CA, Meyer JH, Urrutia R, Miczek KA, Austin MC, Wang J, Paul IA, Woolverton WL, Seo S, Sittman DB, Ou XM) J Biol Chem 2012 Jul 13;287(29):24195-206 PMID: 22628545 PMCID: PMC3397846 SCOPUS ID: 2-s2.0-84863798866 05/26/2012       78 Citations
  • Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. (Hamidi T, Algül H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, Urrutia R, Schmid RM, Iovanna JL) J Clin Invest 2012 Jun;122(6):2092-103 PMID: 22565310 PMCID: PMC3366404 SCOPUS ID: 2-s2.0-84861821128 05/09/2012       102 Citations
  • Krüppel-like factor 11 differentially couples to histone acetyltransferase and histone methyltransferase chromatin remodeling pathways to transcriptionally regulate dopamine D2 receptor in neuronal cells. (Seo S, Lomberk G, Mathison A, Buttar N, Podratz J, Calvo E, Iovanna J, Brimijoin S, Windebank A, Urrutia R) J Biol Chem 2012 Apr 13;287(16):12723-35 PMID: 22375010 PMCID: PMC3339994 SCOPUS ID: 2-s2.0-84859776104 03/01/2012       33 Citations
  • Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases. (Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Rizvi S, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R) J Biol Chem 2012 Apr 13;287(16):13026-39 PMID: 22318730 PMCID: PMC3339955 SCOPUS ID: 2-s2.0-84859753082 02/10/2012       45 Citations
  • Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology. (Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R) J Biol Chem 2012 Mar 02;287(10):7010-25 PMID: 22203677 PMCID: PMC3293586 SCOPUS ID: 2-s2.0-84863280739 12/29/2011       35 Citations
  • MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression. (Xiao TZ, Bhatia N, Urrutia R, Lomberk GA, Simpson A, Longley BJ) PLoS One 2011;6(8):e23747 PMID: 21876767 PMCID: PMC3158099 SCOPUS ID: 2-s2.0-80051858712 08/31/2011       38 Citations
  • Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid. (Singh SK, Baumgart S, Singh G, König AO, Reutlinger K, Hofbauer LC, Barth P, Gress TM, Lomberk G, Urrutia R, Fernandez-Zapico ME, Ellenrieder V) J Biol Chem 2011 Aug 19;286(33):28761-28771 PMID: 21628454 PMCID: PMC3190684 SCOPUS ID: 2-s2.0-80051694778 06/02/2011       22 Citations
  • Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. (Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, Cavé H, Iovanna J, Stein R, Polak M, Vaxillaire M, Froguel P, Urrutia R) J Biol Chem 2011 Aug 12;286(32):28414-24 PMID: 21592955 PMCID: PMC3151084 SCOPUS ID: 2-s2.0-80051527724 05/20/2011       68 Citations
  • Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis. (Thabut D, Routray C, Lomberk G, Shergill U, Glaser K, Huebert R, Patel L, Masyuk T, Blechacz B, Vercnocke A, Ritman E, Ehman R, Urrutia R, Shah V) Hepatology 2011 Aug;54(2):573-85 PMID: 21567441 PMCID: PMC3145033 SCOPUS ID: 2-s2.0-79960714053 05/14/2011       91 Citations
  • Epigenetic silencing of tumor suppressor genes in pancreatic cancer. (Lomberk GA) J Gastrointest Cancer 2011 Jun;42(2):93-9 PMID: 21318291 SCOPUS ID: 2-s2.0-79956201806 02/15/2011       17 Citations
  • A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. (Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R) Biochem J 2011 Apr 15;435(2):529-37 PMID: 21171965 PMCID: PMC3130109 SCOPUS ID: 2-s2.0-79953172903 12/22/2010       83 Citations
  • Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology 2010;10(4):505-16 PMID: 20847583 PMCID: PMC3214918 09/18/2010    
  • Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis. (Rizvi S, Demars CJ, Comba A, Gainullin VG, Rizvi Z, Almada LL, Wang K, Lomberk G, Fernández-Zapico ME, Buttar NS) Cancer Res 2010 Sep 01;70(17):6787-96 PMID: 20647328 PMCID: PMC2954590 SCOPUS ID: 2-s2.0-77956284378 07/22/2010       41 Citations
  • Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. (Bardsley MR, Horváth VJ, Asuzu DT, Lorincz A, Redelman D, Hayashi Y, Popko LN, Young DL, Lomberk GA, Urrutia RA, Farrugia G, Rubin BP, Ordog T) Gastroenterology 2010 Sep;139(3):942-52 PMID: 20621681 PMCID: PMC2933938 SCOPUS ID: 2-s2.0-77956146147 07/14/2010       98 Citations
  • Angiogenesis. (Lomberk G) Pancreatology 2010;10(2-3):112-3 PMID: 20460942 SCOPUS ID: 2-s2.0-77951968538 05/13/2010       2 Citations
  • Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals. (Lomberk GA, Imoto I, Gebelein B, Urrutia R, Cook TA) Pancreatology 2010;10(1):74-84 PMID: 20339309 PMCID: PMC2865486 SCOPUS ID: 2-s2.0-77949871512 03/27/2010       3 Citations
  • The extracellular matrix and cell migration. (Lomberk G) Pancreatology 2010;10(1):4-5 PMID: 20299816 SCOPUS ID: 2-s2.0-77951439761 03/20/2010       5 Citations
  • Distinct role of Kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis. (Buttar NS, DeMars CJ, Lomberk G, Rizvi S, Bonilla-Velez J, Achra S, Rashtak S, Wang KK, Fernandez-Zapico ME, Urrutia R) J Biol Chem 2010 Apr 09;285(15):11433-44 PMID: 20154088 PMCID: PMC2857022 SCOPUS ID: 2-s2.0-77951214442 02/16/2010       36 Citations
  • A team of champions. (Urrutia R) Pancreatology 2010;10(6):III-IV PMID: 21422770 SCOPUS ID: 2-s2.0-79952951028 01/01/2010    
  • 2010-2011 Meetings and conferences (Lomberk G) Pancreatology October 2010;10(4):413-415 SCOPUS ID: 2-s2.0-77955640006 01/01/2010    
  • Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology October 2010;10(4):505-516 SCOPUS ID: 2-s2.0-77956593984 01/01/2010       41 Citations
  • Lipid biology. (Lomberk G) Pancreatology 2009;9(6):722-3 PMID: 20016243 SCOPUS ID: 2-s2.0-72049131346 12/18/2009    
  • Microscopy. (Lomberk G) Pancreatology 2009;9(5):554-5 PMID: 19556828 SCOPUS ID: 2-s2.0-67649211695 06/27/2009    
  • Sin3: master scaffold and transcriptional corepressor. (Grzenda A, Lomberk G, Zhang JS, Urrutia R) Biochim Biophys Acta 2009;1789(6-8):443-50 PMID: 19505602 PMCID: PMC3686104 SCOPUS ID: 2-s2.0-69449089064 06/10/2009       196 Citations
  • Funding opportunities for rare pancreatic diseases. (Lomberk G) Pancreatology 2009;9(4):327-8 PMID: 19468246 SCOPUS ID: 2-s2.0-66049134227 05/27/2009    
  • Primers on molecular pathways--the insulin pathway. (Lomberk G, Urrutia R) Pancreatology 2009;9(3):203-5 PMID: 19299910 SCOPUS ID: 2-s2.0-62449129275 03/21/2009       5 Citations
  • Diabetes. (Lomberk G) Pancreatology 2009;9(3):200-2 PMID: 19299909 SCOPUS ID: 2-s2.0-62449234826 03/21/2009       2 Citations
  • The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research. (Lomberk G, Mathison AJ, Grzenda A, Urrutia R) Curr Opin Gastroenterol 2008 Sep;24(5):597-602 PMID: 19122501 PMCID: PMC2941574 SCOPUS ID: 2-s2.0-55549090720 01/06/2009       18 Citations
  • Krüppel-like factor proteins and chromatin dynamics (Buttar NS, Lomberk GA, Daftary GS, Urrutia RA) The Biology of Krüppel-like Factors 2009:33-49 SCOPUS ID: 2-s2.0-84900216308 01/01/2009       1 Citation
  • Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling. (Truty MJ, Lomberk G, Fernandez-Zapico ME, Urrutia R) J Biol Chem 2009 Mar 06;284(10):6291-300 PMID: 19088080 PMCID: PMC2649086 SCOPUS ID: 2-s2.0-65249180911 12/18/2008       54 Citations
  • Primers on molecular pathways--caspase pathway. (Lomberk G, Urrutia R) Pancreatology 2009;9(1-2):6-8 PMID: 19077449 SCOPUS ID: 2-s2.0-57449121665 12/17/2008       6 Citations
  • Educational websites--Bioinformatics Tools II. (Lomberk G) Pancreatology 2009;9(1-2):4-5 PMID: 19077448 SCOPUS ID: 2-s2.0-57449097441 12/17/2008    
  • Primers on molecular pathways--pain and opioid receptors, I. (Lomberk G, Cruciani R, Urrutia R) Pancreatology 2008;8(6):544-5 PMID: 18818506 SCOPUS ID: 2-s2.0-52349119874 09/27/2008       2 Citations
  • Pain management. (Lomberk G) Pancreatology 2008;8(6):542-3 PMID: 18818505 SCOPUS ID: 2-s2.0-52349114306 09/27/2008       2 Citations
  • Patient advocacy. (Lomberk G) Pancreatology 2008;8(4-5):420-1 PMID: 18714174 SCOPUS ID: 2-s2.0-49549111806 08/21/2008    
  • Societies. (Lomberk G) Pancreatology 2008;8(3):225-6 PMID: 18497535 SCOPUS ID: 2-s2.0-45149117375 05/24/2008    
  • Primers on molecular pathways--notch. (Lomberk G, Urrutia R) Pancreatology 2008;8(2):103-4 PMID: 18382095 SCOPUS ID: 2-s2.0-43449100656 04/03/2008       6 Citations
  • Pharmacogenomics. (Lomberk G) Pancreatology 2008;8(1):4-5 PMID: 18235210 SCOPUS ID: 2-s2.0-42549123995 02/01/2008    
  • Microarray databases I (Lomberk G) Pancreatology May 2008;8(2):101-102 SCOPUS ID: 2-s2.0-43449117759 01/01/2008    
  • Epigenetics. (Lomberk G) Pancreatology 2007;7(5-6):396-7 PMID: 17898528 SCOPUS ID: 2-s2.0-35348916667 09/28/2007       1 Citation
  • Stem cells. (Lomberk G) Pancreatology 2007;7(4):314-6 PMID: 17627095 SCOPUS ID: 2-s2.0-34748873219 07/14/2007       1 Citation
  • Alcohol and pancreas. (Lomberk G) Pancreatology 2007;7(2-3):96-7 PMID: 17570953 SCOPUS ID: 2-s2.0-34447640677 06/16/2007    
  • Laboratory skills. (Lomberk G) Pancreatology 2007;7(1):7-8 PMID: 17259745 SCOPUS ID: 2-s2.0-34248211201 01/30/2007    
  • The Heterochromatin Protein 1 family. (Lomberk G, Wallrath L, Urrutia R) Genome Biol 2006;7(7):228 PMID: 17224041 PMCID: PMC1779566 SCOPUS ID: 2-s2.0-33845192953 01/17/2007       206 Citations
  • Animal models. (Lomberk G) Pancreatology 2006;6(5):427-8 PMID: 16847379 SCOPUS ID: 2-s2.0-39049192001 07/19/2006    
  • Evidence for the existence of an HP1-mediated subcode within the histone code. (Lomberk G, Bensi D, Fernandez-Zapico ME, Urrutia R) Nat Cell Biol 2006 Apr;8(4):407-15 PMID: 16531993 SCOPUS ID: 2-s2.0-33645725188 03/15/2006       159 Citations
  • Educational websites - Signaling pathways (Lomberk G) Pancreatology August 2006;6(4):266-267 SCOPUS ID: 2-s2.0-33748291527 01/01/2006    
  • Educational websites - Cell biology II (Lomberk G) Pancreatology April 2006;6(1-2):5-6 SCOPUS ID: 2-s2.0-33646124220 01/01/2006    
  • The family feud: turning off Sp1 by Sp1-like KLF proteins. (Lomberk G, Urrutia R) Biochem J 2005 Nov 15;392(Pt 1):1-11 PMID: 16266294 PMCID: PMC1317658 SCOPUS ID: 2-s2.0-28044461728 11/04/2005       171 Citations
  • When developmental signaling pathways go wrong and their impact on pancreatic cancer development. (Lomberk G, Fernandez-Zapico ME, Urrutia R) Curr Opin Gastroenterol 2005 Sep;21(5):555-60 PMID: 16093769 SCOPUS ID: 2-s2.0-23944515739 08/12/2005       7 Citations
  • Expression profiling in pancreatic cancer research: the initial steps and the road ahead. (Fernandez-Zapico ME, Callahan G, Delgado S, Urrutia R) Curr Opin Gastroenterol 2003 Sep;19(5):467-72 PMID: 15703590 SCOPUS ID: 2-s2.0-0042887541 02/11/2005    
  • Bioinformatics tools (Lomberk G) Pancreatology 2005;5(4-5):314-315 SCOPUS ID: 2-s2.0-23844481527 01/01/2005       1 Citation
  • Funding opportunities (Lomberk G) Pancreatology 2005;5(1):8-9 SCOPUS ID: 2-s2.0-18744412973 01/01/2005       1 Citation
  • Characterization of FRA6E and its potential role in autosomal recessive juvenile parkinsonism and ovarian cancer. (Denison SR, Callahan G, Becker NA, Phillips LA, Smith DI) Genes Chromosomes Cancer 2003 Sep;38(1):40-52 PMID: 12874785 SCOPUS ID: 2-s2.0-0042522482 07/23/2003       118 Citations
  • Characterization of the common fragile site FRA9E and its potential role in ovarian cancer. (Callahan G, Denison SR, Phillips LA, Shridhar V, Smith DI) Oncogene 2003 Jan 30;22(4):590-601 PMID: 12555072 SCOPUS ID: 2-s2.0-0037473048 01/30/2003       63 Citations
  • Frequent deletions within FRA7G at 7q31.2 in invasive epithelial ovarian cancer. (Huang H, Reed CP, Mordi A, Lomberk G, Wang L, Shridhar V, Hartmann L, Jenkins R, Smith DI) Genes Chromosomes Cancer 1999 Jan;24(1):48-55 PMID: 9892108 SCOPUS ID: 2-s2.0-0032889647 01/19/1999       40 Citations
    • Last update: 04/08/2024