Medical College of Wisconsin
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Linda J. Olson PhD

Linda J. Olson PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Biochemistry

Member of the Cancer Center


Publications

  • Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition. (Olson LJ, Orsi R, Peterson FC, Parodi AJ, Kim JJ, D'Alessio C, Dahms NM) Biochemistry 2015 Jul 07;54(26):4097-111 PMID: 26062005 06/11/2015
  • Bacterial expression of the phosphodiester-binding site of the cation-independent mannose 6-phosphate receptor for crystallographic and NMR studies. (Olson LJ, Jensen DR, Volkman BF, Kim JJ, Peterson FC, Gundry RL, Dahms NM) Protein Expr Purif 2015 Jul;111:91-7 PMID: 25863146 PMCID: PMC4417374 04/12/2015
  • Identification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor. (Olson LJ, Castonguay AC, Lasanajak Y, Peterson FC, Cummings RD, Smith DF, Dahms NM) Glycobiology 2015 Jun;25(6):591-606 PMID: 25573276 PMCID: PMC4410830 01/13/2015
  • Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum. (Olson LJ, Orsi R, Alculumbre SG, Peterson FC, Stigliano ID, Parodi AJ, D'Alessio C, Dahms NM) J Biol Chem 2013 Jun 07;288(23):16460-75 PMID: 23609449 PMCID: PMC3675582 04/24/2013
  • The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates. (Castonguay AC, Lasanajak Y, Song X, Olson LJ, Cummings RD, Smith DF, Dahms NM) Glycobiology 2012 Jul;22(7):983-96 PMID: 22369936 PMCID: PMC3355666 03/01/2012
  • Mannose 6-phosphate receptor homology (MRH) domain-containing lectins in the secretory pathway. (Castonguay AC, Olson LJ, Dahms NM) Biochim Biophys Acta 2011 Sep;1810(9):815-26 PMID: 21723917 PMCID: PMC3150748 07/05/2011
  • Structural basis for recognition of phosphodiester-containing lysosomal enzymes by the cation-independent mannose 6-phosphate receptor. (Olson LJ, Peterson FC, Castonguay A, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Volkman BF, Dahms NM) Proc Natl Acad Sci U S A 2010 Jul 13;107(28):12493-8 PMID: 20615935 PMCID: PMC2906551 07/10/2010
  • Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptor. (Bohnsack RN, Patel M, Olson LJ, Twining SS, Dahms NM) Biochemistry 2010 Jan 26;49(3):635-44 PMID: 20028034 PMCID: PMC2814163 12/24/2009
  • Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Sun G, Bohnsack RN, Peterson FC, Dahms NM, Kim JJ) Biochemistry 2010 Jan 12;49(1):236-46 PMID: 19928875 PMCID: PMC2802658 11/26/2009
  • Cation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sites. (Bohnsack RN, Song X, Olson LJ, Kudo M, Gotschall RR, Canfield WM, Cummings RD, Smith DF, Dahms NM) J Biol Chem 2009 Dec 11;284(50):35215-26 PMID: 19840944 PMCID: PMC2787381 10/21/2009
  • Glycan microarray analysis of P-type lectins reveals distinct phosphomannose glycan recognition. (Song X, Lasanajak Y, Olson LJ, Boonen M, Dahms NM, Kornfeld S, Cummings RD, Smith DF) J Biol Chem 2009 Dec 11;284(50):35201-14 PMID: 19801653 PMCID: PMC2787380 10/06/2009
  • Carbohydrate recognition by the mannose-6-phosphate receptors. (Kim JJ, Olson LJ, Dahms NM) Curr Opin Struct Biol 2009 Oct;19(5):534-42 PMID: 19801188 PMCID: PMC2771201 10/06/2009
  • Strategies for carbohydrate recognition by the mannose 6-phosphate receptors. (Dahms NM, Olson LJ, Kim JJ) Glycobiology 2008 Sep;18(9):664-78 PMID: 18621992 PMCID: PMC2733771 07/16/2008
  • Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Hindsgaul O, Dahms NM, Kim JJ) J Biol Chem 2008 Apr 11;283(15):10124-34 PMID: 18272523 PMCID: PMC2442308 02/15/2008
  • The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor. (Olson LJ, Dahms NM, Kim JJ) J Biol Chem 2004 Aug 06;279(32):34000-9 PMID: 15169779 06/01/2004
  • Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor. (Olson LJ, Yammani RD, Dahms NM, Kim JJ) EMBO J 2004 May 19;23(10):2019-28 PMID: 15085180 PMCID: PMC424385 04/16/2004
  • Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor. (Olson LJ, Zhang J, Dahms NM, Kim JJ) J Biol Chem 2002 Mar 22;277(12):10156-61 PMID: 11786557 01/12/2002
  • Mutational analysis of the binding site residues of the bovine cation-dependent mannose 6-phosphate receptor. (Olson LJ, Hancock MK, Dix D, Kim JJ, Dahms NM) J Biol Chem 1999 Dec 24;274(52):36905-11 PMID: 10601243 12/22/1999
  • Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Zhang J, Lee YC, Dahms NM, Kim JJ) J Biol Chem 1999 Oct 15;274(42):29889-96 PMID: 10514470 10/09/1999
  • Functionally active catalytic domain is essential for guanylyl cyclase-linked receptor mediated inhibition of human aldosterone synthesis. (Olson LJ, Ho BY, Cashdollar LW, Drewett JG) Mol Pharmacol 1998 Nov;54(5):761-9 PMID: 9804611 11/06/1998
  • Selective guanylyl cyclase inhibitor reverses nitric oxide-induced vasorelaxation. (Olson LJ, Knych ET Jr, Herzig TC, Drewett JG) Hypertension 1997 Jan;29(1 Pt 2):254-61 PMID: 9039111 01/01/1997
  • Novel natriuretic peptide receptor/guanylyl cyclase A-selective agonist inhibits angiotensin II- and forskolin-evoked aldosterone synthesis in a human zona glomerulosa cell line. (Olson LJ, Lowe DG, Drewett JG) Mol Pharmacol 1996 Aug;50(2):430-5 PMID: 8700153 08/01/1996
  • Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR. (Draeger LJ, Mullen GP) J Biol Chem 1994 Jan 21;269(3):1785-93 PMID: 8294427 01/21/1994
  • Last update: 03/01/2017
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