Medical College of Wisconsin
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Veronica H. Flood MD

Veronica H. Flood MD profile photo picture


Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Hematology and Oncology - Pediatrics
Program: Hematology

Research Experience

  • Blood Coagulation Disorders
  • Blood Coagulation Tests
  • Blood Platelets
  • Factor VIII
  • Fibrin
  • Fibrinogen
  • Fibrinolysis
  • Platelet Aggregation
  • Platelet Function Tests
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Glycoprotein GPIb-IX Complex
  • von Willebrand Diseases
  • von Willebrand Factor
  • Clinical Expertise

  • Blood Coagulation Disorders
  • Coagulation Protein Disorders
  • Hematologic Diseases
  • Hematology
  • Hemorrhagic Disorders
  • Thrombosis
  • von Willebrand Diseases
  • Publications (50)

  • von Willebrand disease: proposing definitions for future research. (Connell NT, James PD, Brignardello-Petersen R, Abdul-Kadir R, Ameer B, Arapshian A, Couper S, Di Paola J, Eikenboom J, Giraud N, Grow JM, Haberichter S, Jacobs-Pratt V, Konkle BA, Kouides P, Laffan M, Lavin M, Leebeek FWG, McLintock C, McRae S, Montgomery R, O'Brien SH, O'Donnell JS, Ozelo MC, Scappe N, Sidonio R, Tosetto A, Weyand AC, Kalot MA, Husainat N, Mustafa RA, Flood VH) Blood Adv 2021 Jan 26;5(2):565-569 PMID: 33496750 PMCID: PMC7839375 01/27/2021    
  • Laboratory variability in the diagnosis of type 2 VWD variants. (DiGiandomenico S, Christopherson PA, Haberichter SL, Abshire TC, Montgomery RR, Flood VH, Zimmerman Program Investigators) J Thromb Haemost 2021 Jan;19(1):131-138 PMID: 33049112 PMCID: PMC7790985 SCOPUS ID: 2-s2.0-85100279861 10/14/2020    
  • von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions. (Lohmeier HK, Slobodianuk TL, Kanaji S, Haberichter SL, Montgomery RR, Flood VH) Blood Adv 2020 Sep 08;4(17):4065-4068 PMID: 32870970 PMCID: PMC7479953 SCOPUS ID: 2-s2.0-85100184214 09/02/2020    
  • A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9. (Garcia J, Flood VH, Haberichter SL, Fahs SA, Mattson JG, Geurts AM, Zogg M, Weiler H, Shi Q, Montgomery RR) Res Pract Thromb Haemost 2020 Jan;4(1):64-71 PMID: 31989086 PMCID: PMC6971331 01/29/2020    
  • von Willebrand factor binding to myosin assists in coagulation. (Flood VH, Slobodianuk TL, Keesler D, Lohmeier HK, Fahs S, Zhang L, Simpson P, Montgomery RR) Blood Adv 2020 01 14;4(1):174-180 PMID: 31935285 PMCID: PMC6960459 SCOPUS ID: 2-s2.0-85078090866 01/15/2020       2 Citations
  • Low VWF levels in children and lack of association with bleeding in children undergoing tonsillectomy. (Gill JC, Conley SF, Johnson VP, Christopherson PA, Haberichter SL, Diaz CD, Strong TC, Zhang J, Simpson P, Abshire TC, Montgomery RR, Flood VH) Blood Adv 2020 01 14;4(1):100-105 PMID: 31905240 PMCID: PMC6960478 SCOPUS ID: 2-s2.0-85078147321 01/07/2020       5 Citations
  • An international survey to inform priorities for new guidelines on von Willebrand disease. (Kalot MA, Al-Khatib M, Connell NT, Flood V, Brignardello-Petersen R, James P, Mustafa RA, VWD working group) Haemophilia 2020 Jan;26(1):106-116 PMID: 31769905 PMCID: PMC7041556 SCOPUS ID: 2-s2.0-85076016135 11/27/2019       4 Citations
  • Efficacy of emicizumab in a pediatric patient with type 3 von Willebrand disease and alloantibodies. (Weyand AC, Flood VH, Shavit JA, Pipe SW) Blood Adv 2019 09 24;3(18):2748-2750 PMID: 31540901 PMCID: PMC6759735 SCOPUS ID: 2-s2.0-85073477829 09/22/2019       6 Citations
  • The role of genetics in the pathogenesis and diagnosis of type 1 Von Willebrand disease. (Flood VH, Garcia J, Haberichter SL) Curr Opin Hematol 2019 09;26(5):331-335 PMID: 31261173 PMCID: PMC6727843 SCOPUS ID: 2-s2.0-85070848175 07/02/2019       1 Citation
  • Defective collagen binding and increased bleeding in a murine model of von Willebrand disease affecting collagen IV binding. (Slobodianuk TL, Kochelek C, Foeckler J, Kalloway S, Weiler H, Flood VH) J Thromb Haemost 2019 01;17(1):63-71 PMID: 30565388 PMCID: PMC6743498 SCOPUS ID: 2-s2.0-85058806961 12/20/2018       3 Citations
  • Von Willebrand disease in the United States: perspective from the Zimmerman program. (Flood VH, Abshire TC, Christopherson PA, Friedman KD, Cox Gill J, Montgomery RR, Haberichter SL, Zimmerman Program Investigators) Ann Blood 2018 Jan;3 PMID: 30135959 PMCID: PMC6100783 08/24/2018    
  • Common VWF sequence variants associated with higher VWF and FVIII are less frequent in subjects diagnosed with type 1 VWD. (Flood VH, Johnsen JM, Kochelek C, Slobodianuk TL, Christopherson PA, Haberichter SL, Udani R, Bellissimo DB, Friedman KD, Montgomery RR) Res Pract Thromb Haemost 2018 Apr;2(2):390-398 PMID: 30046743 PMCID: PMC5974909 07/27/2018    
  • Current issues in diagnosis and treatment of von Willebrand disease. (Keesler DA, Flood VH) Res Pract Thromb Haemost 2018 Jan;2(1):34-41 PMID: 30046704 PMCID: PMC5974913 07/27/2018    
  • Treatment Modalities in Adolescents Who Present with Heavy Menstrual Bleeding. (Alaqzam TS, Stanley AC, Simpson PM, Flood VH, Menon S) J Pediatr Adolesc Gynecol 2018 Oct;31(5):451-458 PMID: 29524595 SCOPUS ID: 2-s2.0-85047315300 03/11/2018       10 Citations
  • Advances in the diagnosis and treatment of Von Willebrand disease. (Sharma R, Flood VH) Hematology Am Soc Hematol Educ Program 2017 12 08;2017(1):379-384 PMID: 29222282 PMCID: PMC6142610 SCOPUS ID: 2-s2.0-85038434846 12/10/2017       7 Citations
  • Advances in the diagnosis and treatment of Von Willebrand disease. (Sharma R, Flood VH) Blood 2017 11 30;130(22):2386-2391 PMID: 29187375 PMCID: PMC5709787 SCOPUS ID: 2-s2.0-85036542444 12/01/2017       26 Citations
  • von Willebrand disease Outreach into Integrated Care Education (VOICE): a call to action. (Wang M, Konkle BA, Sidonio RF Jr, Flood V, Koenig C, Kulkarni R) Haemophilia 2017 07;23(4):e370-e373 PMID: 28548287 SCOPUS ID: 2-s2.0-85019686070 05/27/2017       1 Citation
  • Clinical and laboratory phenotype variability in type 2M von Willebrand disease. (Doruelo AL, Haberichter SL, Christopherson PA, Boggio LN, Gupta S, Lentz SR, Shapiro AD, Montgomery RR, Flood VH) J Thromb Haemost 2017 08;15(8):1559-1566 PMID: 28544236 PMCID: PMC5538962 SCOPUS ID: 2-s2.0-85021241191 05/26/2017       4 Citations
  • Bleeding and Thrombosis (Flood VH, Scott JP) Nelson Pediatric Symptom-Based Diagnosis 24 April 2017:682-701 SCOPUS ID: 2-s2.0-85054410686 04/24/2017    
  • What have we learned from large population studies of von Willebrand disease? (Montgomery RR, Flood VH) Hematology Am Soc Hematol Educ Program 2016 Dec 02;2016(1):670-677 PMID: 27913545 PMCID: PMC5518316 SCOPUS ID: 2-s2.0-85020267077 12/04/2016       5 Citations
  • Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States. (Flood VH, Christopherson PA, Gill JC, Friedman KD, Haberichter SL, Bellissimo DB, Udani RA, Dasgupta M, Hoffmann RG, Ragni MV, Shapiro AD, Lusher JM, Lentz SR, Abshire TC, Leissinger C, Hoots WK, Manco-Johnson MJ, Gruppo RA, Boggio LN, Montgomery KT, Goodeve AC, James PD, Lillicrap D, Peake IR, Montgomery RR) Blood 2016 05 19;127(20):2481-8 PMID: 26862110 PMCID: PMC4874228 SCOPUS ID: 2-s2.0-84974556876 02/11/2016       54 Citations
  • Women leaders in hematology: Inspirations & insights. (Quon D, Chitlur M, Rajpurkar M, Simpson M, O'Brien S, Flood V, Hsieh L, Acharya S, Kruse-Jarres R, Sood S, Maahs J) Am J Hematol 2016 Apr;91 Suppl 1:S6-S34 PMID: 26851875 SCOPUS ID: 2-s2.0-84960395649 02/08/2016    
  • Von Willebrand factor is reversibly decreased during torpor in 13-lined ground squirrels. (Cooper S, Sell S, Nelson L, Hawes J, Benrud JA, Kohlnhofer BM, Burmeister BR, Flood VH) J Comp Physiol B 2016 Jan;186(1):131-9 PMID: 26481634 PMCID: PMC4838567 SCOPUS ID: 2-s2.0-84953368104 10/21/2015       7 Citations
  • Platelet-derived VWF in the stroke spotlight. (Flood VH) Blood 2015 Oct 01;126(14):1640-1 PMID: 26429965 PMCID: PMC4591789 SCOPUS ID: 2-s2.0-84947930549 10/03/2015       1 Citation
  • Variable content of von Willebrand factor mutant monomer drives the phenotypic variability in a family with von Willebrand disease. (Chen J, Hinckley JD, Haberichter S, Jacobi P, Montgomery R, Flood VH, Wong R, Interlandi G, Chung DW, López JA, Di Paola J) Blood 2015 Jul 09;126(2):262-9 PMID: 26019279 PMCID: PMC4497966 SCOPUS ID: 2-s2.0-84937953557 05/29/2015       9 Citations
  • Laboratory diagnosis of von Willebrand disease. (Roberts JC, Flood VH) Int J Lab Hematol 2015 May;37 Suppl 1:11-7 PMID: 25976955 PMCID: PMC5600156 SCOPUS ID: 2-s2.0-84929298745 05/16/2015       14 Citations
  • New insights into genotype and phenotype of VWD. (Flood VH) Hematology Am Soc Hematol Educ Program 2014 Dec 05;2014(1):531-5 PMID: 25696906 PMCID: PMC4696506 SCOPUS ID: 2-s2.0-84937572618 02/20/2015       15 Citations
  • Crucial role for the VWF A1 domain in binding to type IV collagen. (Flood VH, Schlauderaff AC, Haberichter SL, Slobodianuk TL, Jacobi PM, Bellissimo DB, Christopherson PA, Friedman KD, Gill JC, Hoffmann RG, Montgomery RR, Zimmerman Program Investigators) Blood 2015 Apr 02;125(14):2297-304 PMID: 25662333 PMCID: PMC4383803 SCOPUS ID: 2-s2.0-84926664083 02/11/2015       49 Citations
  • Perils, problems, and progress in laboratory diagnosis of von Willebrand disease. (Flood VH) Semin Thromb Hemost 2014 Feb;40(1):41-8 PMID: 24338593 PMCID: PMC3987108 SCOPUS ID: 2-s2.0-84893041204 12/18/2013       34 Citations
  • Vitamin B12 deficiency: the great masquerader. (Dobrozsi S, Flood VH, Panepinto J, Scott JP, Brandow A) Pediatr Blood Cancer 2014 Apr;61(4):753-5 PMID: 24115632 SCOPUS ID: 2-s2.0-84893471917 10/12/2013       15 Citations
  • No increase in bleeding identified in type 1 VWD subjects with D1472H sequence variation. (Flood VH, Friedman KD, Gill JC, Haberichter SL, Christopherson PA, Branchford BR, Hoffmann RG, Abshire TC, Dunn AL, Di Paola JA, Hoots WK, Brown DL, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR) Blood 2013 May 02;121(18):3742-4 PMID: 23520336 PMCID: PMC3643771 SCOPUS ID: 2-s2.0-84879719268 03/23/2013       20 Citations
  • Variability in platelet- and collagen-binding defects in type 2M von Willebrand disease. (Larsen DM, Haberichter SL, Gill JC, Shapiro AD, Flood VH) Haemophilia 2013 Jul;19(4):590-4 PMID: 23496210 PMCID: PMC3688679 SCOPUS ID: 2-s2.0-84879459941 03/19/2013       21 Citations
  • Third Åland islands conference on von Willebrand disease, 26-28 September 2012: meeting report. (Berntorp E, Fuchs B, Makris M, Montgomery R, Flood V, O'Donnell JS, Federici AB, Lillicrap D, James P, Budde U, Morfini M, Petrini P, Austin S, Kannicht C, Jiménez-Yuste V, Lee C) Haemophilia 2013 Mar;19 Suppl 3:1-18 PMID: 23383607 PMCID: PMC4164969 SCOPUS ID: 2-s2.0-84873425397 02/13/2013       5 Citations
  • Collagen binding provides a sensitive screen for variant von Willebrand disease. (Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Hoffmann RG, Montgomery RR, Haberichter SL, Zimmerman Program Investigators) Clin Chem 2013 Apr;59(4):684-91 PMID: 23340442 PMCID: PMC3852672 SCOPUS ID: 2-s2.0-84875860574 01/24/2013       43 Citations
  • Use of purified fibrinogen concentrate for dysfibrinogenemia and importance of laboratory fibrinogen activity measurement. (Franzblau EB, Punzalan RC, Friedman KD, Roy A, Bilen O, Flood VH) Pediatr Blood Cancer 2013 Mar;60(3):500-2 PMID: 23129109 PMCID: PMC4461026 SCOPUS ID: 2-s2.0-84872441623 11/07/2012       4 Citations
  • Comparison of type I, type III and type VI collagen binding assays in diagnosis of von Willebrand disease. (Flood VH, Gill JC, Christopherson PA, Wren JS, Friedman KD, Haberichter SL, Hoffmann RG, Montgomery RR) J Thromb Haemost 2012 Jul;10(7):1425-32 PMID: 22507643 PMCID: PMC3809762 SCOPUS ID: 2-s2.0-84863455676 04/18/2012       34 Citations
  • Critical von Willebrand factor A1 domain residues influence type VI collagen binding. (Flood VH, Gill JC, Christopherson PA, Bellissimo DB, Friedman KD, Haberichter SL, Lentz SR, Montgomery RR) J Thromb Haemost 2012 Jul;10(7):1417-24 PMID: 22507569 PMCID: PMC3809952 SCOPUS ID: 2-s2.0-84863422773 04/18/2012       43 Citations
  • Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage. (Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL) Blood 2012 May 10;119(19):4543-53 PMID: 22431572 PMCID: PMC3362367 SCOPUS ID: 2-s2.0-84861068515 03/21/2012       34 Citations
  • VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population. (Bellissimo DB, Christopherson PA, Flood VH, Gill JC, Friedman KD, Haberichter SL, Shapiro AD, Abshire TC, Leissinger C, Hoots WK, Lusher JM, Ragni MV, Montgomery RR) Blood 2012 Mar 01;119(9):2135-40 PMID: 22197721 PMCID: PMC3311248 SCOPUS ID: 2-s2.0-84857720362 12/27/2011       61 Citations
  • Von Willebrand disease in the United States: a perspective from Wisconsin. (Flood VH, Gill JC, Friedman KD, Bellissimo DB, Haberichter SL, Montgomery RR) Semin Thromb Hemost 2011 Jul;37(5):528-34 PMID: 22102196 PMCID: PMC3807766 SCOPUS ID: 2-s2.0-81755171917 11/22/2011       21 Citations
  • Gain-of-function GPIb ELISA assay for VWF activity in the Zimmerman Program for the Molecular and Clinical Biology of VWD. (Flood VH, Gill JC, Morateck PA, Christopherson PA, Friedman KD, Haberichter SL, Hoffmann RG, Montgomery RR) Blood 2011 Feb 10;117(6):e67-74 PMID: 21148813 PMCID: PMC3056647 SCOPUS ID: 2-s2.0-79951469339 12/15/2010       71 Citations
  • von Willebrand Disease: Biologic Diagnosis (Flood VH, Montgomery RR) Textbook of Hemophilia: Second Edition 13 August 2010:294-301 SCOPUS ID: 2-s2.0-84885794685 08/13/2010    
  • Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD. (Flood VH, Lederman CA, Wren JS, Christopherson PA, Friedman KD, Hoffmann RG, Montgomery RR) J Thromb Haemost 2010 Jun;8(6):1431-3 PMID: 20345715 PMCID: PMC3892206 SCOPUS ID: 2-s2.0-77954496769 03/30/2010       58 Citations
  • Common VWF exon 28 polymorphisms in African Americans affecting the VWF activity assay by ristocetin cofactor. (Flood VH, Gill JC, Morateck PA, Christopherson PA, Friedman KD, Haberichter SL, Branchford BR, Hoffmann RG, Abshire TC, Di Paola JA, Hoots WK, Leissinger C, Lusher JM, Ragni MV, Shapiro AD, Montgomery RR) Blood 2010 Jul 15;116(2):280-6 PMID: 20231421 PMCID: PMC2910611 SCOPUS ID: 2-s2.0-77955499972 03/17/2010       102 Citations
  • Limitations of the ristocetin cofactor assay in measurement of von Willebrand factor function. (Flood VH, Friedman KD, Gill JC, Morateck PA, Wren JS, Scott JP, Montgomery RR) J Thromb Haemost 2009 Nov;7(11):1832-9 PMID: 19694940 PMCID: PMC3825106 SCOPUS ID: 2-s2.0-70449436494 08/22/2009       58 Citations
  • Fibrinogen Hershey IV: a novel dysfibrinogen with a gammaV411I mutation in the integrin alpha(IIb)beta(3) binding site. (Flood VH, Al-Mondhiry HA, Rein CM, Alexander KS, Lovely RS, Shackleton KM, David LL, Farrell DH) Thromb Haemost 2008 Jun;99(6):1008-12 PMID: 18521501 PMCID: PMC4089099 SCOPUS ID: 2-s2.0-44949196653 06/04/2008       5 Citations
  • Hemorrhagic disease of the newborn despite vitamin K prophylaxis at birth. (Flood VH, Galderisi FC, Lowas SR, Kendrick A, Boshkov LK) Pediatr Blood Cancer 2008 May;50(5):1075-7 PMID: 17957759 SCOPUS ID: 2-s2.0-41849099695 10/25/2007       22 Citations
  • Incorporation of fibrin molecules containing fibrinopeptide A alters clot ultrastructure and decreases permeability. (Flood VH, Nagaswami C, Chernysh IN, Al-Mondhiry HA, Weisel JW, Farrell DH) Br J Haematol 2007 Jul;138(1):117-24 PMID: 17555455 SCOPUS ID: 2-s2.0-34249987934 06/09/2007       6 Citations
  • The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance. (Flood VH, Al-Mondhiry HA, Farrell DH) Br J Haematol 2006 Jul;134(2):220-6 PMID: 16846481 SCOPUS ID: 2-s2.0-33745158288 07/19/2006       18 Citations
  • Sustained engraftment post bone marrow transplant despite anti-platelet antibodies in Glanzmann thrombasthenia. (Flood VH, Johnson FL, Boshkov LK, Thomas GA, Nugent DJ, Bakke AC, Nicholson HS, Tilford D, Brown MP, Godder KT) Pediatr Blood Cancer 2005 Dec;45(7):971-5 PMID: 15768382 SCOPUS ID: 2-s2.0-27644524098 03/16/2005       27 Citations
  • Last update: 01/27/2021