Faculty Collaboration Database

Surveillance cultures following a regional outbreak of carbapenem-resistant Acinetobacter baumannii. Infect Control Hosp Epidemiol 2022 Apr;43(4):454-460

Date

05/15/2021

Pubmed ID

33985611

DOI

10.1017/ice.2021.162

Scopus ID

2-s2.0-85105848855 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

OBJECTIVES: The primary aim of this study was to assess the epidemiology of carbapenem-resistant Acinetobacter baumannii (CRAB) for 9 months following a regional outbreak with this organism. We also aimed to determine the differential positivity rate from different body sites and characterize the longitudinal changes of surveillance test results among CRAB patients.

DESIGN: Observational study.

SETTING: A 607-bed tertiary-care teaching hospital in Milwaukee, Wisconsin.

PATIENTS: Any patient admitted from postacute care facilities and any patient housed in the same inpatient unit as a positive CRAB patient.

METHODS: Participants underwent CRAB surveillance cultures from tracheostomy secretions, skin, and stool from December 5, 2018, to September 6, 2019. Cultures were performed using a validated, qualitative culture method, and final bacterial identification was performed using mass spectrometry.

RESULTS: In total, 682 patients were tested for CRAB, of whom 16 (2.3%) were positive. Of the 16 CRAB-positive patients, 14 (87.5%) were residents from postacute care facilities and 11 (68.8%) were African American. Among positive patients, the positivity rates by body site were 38% (6 of 16) for tracheal aspirations, 56% (9 of 16) for skin, and 82% (13 of 16) for stool.

CONCLUSIONS: Residents from postacute care facilities were more frequently colonized by CRAB than patients admitted from home. Stool had the highest yield for identification of CRAB.

Author List

Rivera F, Reeme A, Graham MB, Buchan BW, Ledeboer NA, Valley AM, Munoz-Price LS

Authors

Blake W. Buchan PhD Professor in the Pathology department at Medical College of Wisconsin
Mary Beth Graham MD Associate Chief, Professor in the Medicine department at Medical College of Wisconsin
Nathan A. Ledeboer PhD Vice Chair, Professor in the Pathology department at Medical College of Wisconsin
Allison Reeme in the CTSI department at Medical College of Wisconsin - CTSI

MESH terms used to index this publication - Major topics in bold

Acinetobacter Infections
Acinetobacter baumannii
Anti-Bacterial Agents
Carbapenems
Cross Infection
Humans
Microbial Sensitivity Tests