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Hypoprothrombinemia: case report. Blood 1978 Feb;51(2):299-306

Date

02/01/1978

Pubmed ID

620085

DOI

10.1182/blood.v51.2.299.299

Scopus ID

2-s2.0-0017798727 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

A patient with a significant history of spontaneous and posttraumatic bleeding was found to have hypoprothrombinemia. His prothrombin (factor II) activity by clotting assay was 9.5% and his factor II antigen was 5%. Crossed immunoelectrophoresis and sucrose density gradient ultracentrifugation of the patient's plasma showed his prothrombin to be qualitatively indistinguishable from normal prothrombin by these techniques.

Author List

Montgomery RR, Otsuka A, Hathaway WE

Author

Robert R. Montgomery MD Adjunct Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Blood Coagulation Tests
Centrifugation, Density Gradient
Humans
Hypoprothrombinemias
Immunoelectrophoresis, Two-Dimensional
Male