Integration of Toll-like receptor and phagocytic signaling for tailored immunity. Microbes Infect 2004 Dec;6(15):1368-73
Date
12/15/2004Pubmed ID
15596122DOI
10.1016/j.micinf.2004.08.016Scopus ID
2-s2.0-16644380633 (requires institutional sign-in at Scopus site) 125 CitationsAbstract
Toll-like receptors (TLRs) are recruited to phagosomes and sample the contents of the compartment for microbial products. In this review, we discuss the relationship between phagocytosis and TLRs from two additional perspectives: first, TLR signaling modulates phagocytosis; second, phagocytosis modulates the consequences of TLR activation.
Author List
Underhill DM, Gantner BAuthor
Benjamin N. Gantner PhD Assistant Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsAntigens, Differentiation
Humans
Immunity, Innate
Membrane Glycoproteins
Phagocytosis
Receptors, Cell Surface
Receptors, Immunologic
Signal Transduction
Toll-Like Receptors