Faculty Collaboration Database

Integration of Toll-like receptor and phagocytic signaling for tailored immunity. Microbes Infect 2004 Dec;6(15):1368-73

Date

12/15/2004

Pubmed ID

15596122

DOI

10.1016/j.micinf.2004.08.016

Scopus ID

2-s2.0-16644380633   114 Citations

Abstract

Toll-like receptors (TLRs) are recruited to phagosomes and sample the contents of the compartment for microbial products. In this review, we discuss the relationship between phagocytosis and TLRs from two additional perspectives: first, TLR signaling modulates phagocytosis; second, phagocytosis modulates the consequences of TLR activation.

Author List

Underhill DM, Gantner B

Author

Benjamin N. Gantner PhD Assistant Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Antigens, Differentiation
Humans
Immunity, Innate
Membrane Glycoproteins
Phagocytosis
Receptors, Cell Surface
Receptors, Immunologic
Signal Transduction
Toll-Like Receptors