Medical College of Wisconsin
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Benjamin N. Gantner PhD

Benjamin N. Gantner PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Research

Member of the Cancer Center
Member of the Cardiovascular Research Center
Member of the Center for Immunology

View Curriculum Vitae

Publications (30)

  • Metabolism and epigenetics: drivers of tumor cell plasticity and treatment outcomes. (Gantner BN, Palma FR, Pandkar MR, Sakiyama MJ, Arango D, DeNicola GM, Gomes AP, Bonini MG) Trends Cancer 2024 Nov;10(11):992-1008 PMID: 39277448 SCOPUS ID: 2-s2.0-85203805048 09/15/2024       10 Citations
  • Erratum: Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance (Cell Reports (2024) 43(3), (S2211124724002250), (10.1016/j.celrep.2024.113897)) (Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG) Cell Reports 23 July 2024;43(7) SCOPUS ID: 2-s2.0-85196720962 07/23/2024       2 Citations
  • Prolonged warm ischemia time increases mitogen-activated protein kinase activity and decreases perfusate cytokine levels in ex vivo rat liver machine perfusion. (Kim J, Hong SK, Yang Y, Lee A, Hoffmeister KM, Gantner BN, Park JI) Front Transplant 2023;2:1215182 PMID: 38993858 PMCID: PMC11235240 SCOPUS ID: 2-s2.0-85204385238 07/12/2024       2 Citations
  • Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance. (Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG) Cell Rep 2024 Jul 23;43(7):114415 PMID: 38923462 PMCID: PMC11560056 SCOPUS ID: 2-s2.0-85196720962 06/26/2024       2 Citations
  • Histone oxidation as a new mechanism of metabolic control over gene expression. (Gantner BN, Palma FR, Kayzuka C, Lacchini R, Foltz DR, Backman V, Kelleher N, Shilatifard A, Bonini MG) Trends Genet 2024 Sep;40(9):739-746 PMID: 38910033 PMCID: PMC11387142 SCOPUS ID: 2-s2.0-85196478706 06/24/2024       7 Citations
  • Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance. (Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG) Cell Rep 2024 Mar 26;43(3):113897 PMID: 38493478 PMCID: PMC11209755 SCOPUS ID: 2-s2.0-85188001867 03/17/2024       17 Citations
  • ROS production by mitochondria: function or dysfunction? (Palma FR, Gantner BN, Sakiyama MJ, Kayzuka C, Shukla S, Lacchini R, Cunniff B, Bonini MG) Oncogene 2024 Jan;43(5):295-303 PMID: 38081963 SCOPUS ID: 2-s2.0-85179332430 12/12/2023       296 Citations
  • SOCS1 regulates a subset of NFκB-target genes through direct chromatin binding and defines macrophage functional phenotypes. (Coelho DR, Palma FR, Paviani V, LaFond KM, Huang Y, Wang D, Wray B, Rao S, Yue F, Bonini MG, Gantner BN) iScience 2023 Apr 21;26(4):106442 PMID: 37020964 PMCID: PMC10068561 SCOPUS ID: 2-s2.0-85151424842 04/07/2023       6 Citations
  • Collagen-Specific HSP47+ Myofibroblasts and CD163+ Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS-CoV-2 Infections. (Puzyrenko A, Jacobs ER, Padilla N, Devine A, Aljadah M, Gantner BN, Pan AY, Lai S, Dai Q, Rubenstein JC, North PE, Simpson PM, Willoughby RE, O'Meara CC, Flinn MA, Lough JW, Ibrahim EH, Zheng Z, Sun Y, Felix J, Hunt BC, Ross G, Rui H, Benjamin IJ) J Am Heart Assoc 2023 Feb 21;12(4):e027990 PMID: 36789856 PMCID: PMC10111490 SCOPUS ID: 2-s2.0-85148479620 02/16/2023       9 Citations
  • Pcpe2, a Novel Extracellular Matrix Protein, Regulates Adipocyte SR-BI-Mediated High-Density Lipoprotein Uptake. (Xu H, Thomas MJ, Kaul S, Kallinger R, Ouweneel AB, Maruko E, Oussaada SM, Jongejan A, Cense HA, Nieuwdorp M, Serlie MJ, Goldberg IJ, Civelek M, Parks BW, Lusis AJ, Knaack D, Schill RL, May SC, Reho JJ, Grobe JL, Gantner B, Sahoo D, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2021 Nov;41(11):2708-2725 PMID: 34551590 PMCID: PMC8551036 SCOPUS ID: 2-s2.0-85118592107 09/24/2021       14 Citations
  • Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 autopsies. (Puzyrenko A, Jacobs ER, Sun Y, Felix JC, Sheinin Y, Ge L, Lai S, Dai Q, Gantner BN, Nanchal R, North PE, Simpson PM, Rui H, Benjamin IJ) Cell Stress Chaperones 2021 Sep;26(5):859-868 PMID: 34382151 PMCID: PMC8357488 SCOPUS ID: 2-s2.0-85112285201 08/13/2021       24 Citations
  • Inorganic arsenic promotes luminal to basal transition and metastasis of breast cancer. (Danes JM, de Abreu ALP, Kerketta R, Huang Y, Palma FR, Gantner BN, Mathison AJ, Urrutia RA, Bonini MG) FASEB J 2020 Dec;34(12):16034-16048 PMID: 33047385 PMCID: PMC8289339 SCOPUS ID: 2-s2.0-85092336914 10/14/2020       13 Citations
  • Nitric oxide in cellular adaptation and disease (Gantner BN, LaFond KM, Bonini MG) Redox Biology July 2020;34 SCOPUS ID: 2-s2.0-85084644297 07/01/2020       169 Citations
  • Nitric oxide in cellular adaptation and disease. (Gantner BN, LaFond KM, Bonini MG) Redox Biol 2020 Jul;34:101550 PMID: 32438317 PMCID: PMC7235643 SCOPUS ID: 2-s2.0-85084644297 05/22/2020       169 Citations
  • Acquired Immunity Is Not Essential for Radiation-Induced Heart Dysfunction but Exerts a Complex Impact on Injury. (Schlaak RA, Frei A, Fish BL, Harmann L, Gasperetti T, Pipke JL, Sun Y, Rui H, Flister MJ, Gantner BN, Bergom C) Cancers (Basel) 2020 Apr 16;12(4) PMID: 32316187 PMCID: PMC7226421 SCOPUS ID: 2-s2.0-85083724334 04/23/2020       10 Citations
  • Nitric oxide in cellular adaptation and disease (Benjamin N. Gantner, Katy M. LaFond, Marcelo G. Bonini) Redox Biology B.N. Gantner, K.M. LaFond, M.G. Bonini, Nitric oxide in cellular adaptation and disease, Redox Biology (2020), doi: https://doi.org/10.1016/j.redox.2020.101550. 04/20/2020    
  • Mitochondrial Superoxide Dismutase: What the Established, the Intriguing, and the Novel Reveal About a Key Cellular Redox Switch. (Palma FR, He C, Danes JM, Paviani V, Coelho DR, Gantner BN, Bonini MG) Antioxid Redox Signal 2020 Apr 01;32(10):701-714 PMID: 31968997 PMCID: PMC7047081 SCOPUS ID: 2-s2.0-85081092325 01/24/2020       152 Citations
  • SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. (He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG) Proc Natl Acad Sci U S A 2019 Nov 19;116(47):23534-23541 PMID: 31591207 PMCID: PMC6876149 SCOPUS ID: 2-s2.0-85075260452 10/09/2019       68 Citations
  • NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1. (Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG) J Exp Med 2015 Sep 21;212(10):1725-38 PMID: 26324446 PMCID: PMC4577833 SCOPUS ID: 2-s2.0-84961216724 09/02/2015       105 Citations
  • The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all? (Bonini MG, Gantner BN) IUBMB Life 2013 Nov;65(11):889-96 PMID: 24265196 SCOPUS ID: 2-s2.0-84888419827 11/23/2013       47 Citations
  • The Listeria monocytogenes ChiA chitinase enhances virulence through suppression of host innate immunity. (Chaudhuri S, Gantner BN, Ye RD, Cianciotto NP, Freitag NE) mBio 2013 Mar 19;4(2):e00617-12 PMID: 23512964 PMCID: PMC3604766 SCOPUS ID: 2-s2.0-84880078857 03/21/2013       52 Citations
  • Bioluminescent detection of peroxynitrite with a boronic acid-caged luciferin. (Sieracki NA, Gantner BN, Mao M, Horner JH, Ye RD, Malik AB, Newcomb ME, Bonini MG) Free Radic Biol Med 2013 Aug;61:40-50 PMID: 23474271 PMCID: PMC3795912 SCOPUS ID: 2-s2.0-84878846249 03/12/2013       40 Citations
  • The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin. (Gantner BN, Jin H, Qian F, Hay N, He B, Ye RD) J Immunol 2012 Sep 15;189(6):3104-11 PMID: 22904301 PMCID: PMC3658160 SCOPUS ID: 2-s2.0-84866179288 08/21/2012       31 Citations
  • Map kinase phosphatase 5 protects against sepsis-induced acute lung injury. (Qian F, Deng J, Gantner BN, Flavell RA, Dong C, Christman JW, Ye RD) Am J Physiol Lung Cell Mol Physiol 2012 May 01;302(9):L866-74 PMID: 22307906 PMCID: PMC3362165 SCOPUS ID: 2-s2.0-84860513125 02/07/2012       49 Citations
  • Immunology: Short-term memory. (Gantner BN, Singh H) Nature 2007 Jun 21;447(7147):916-7 PMID: 17581569 SCOPUS ID: 2-s2.0-34250817466 06/22/2007       9 Citations
  • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. (Laslo P, Spooner CJ, Warmflash A, Lancki DW, Lee HJ, Sciammas R, Gantner BN, Dinner AR, Singh H) Cell 2006 Aug 25;126(4):755-66 PMID: 16923394 SCOPUS ID: 2-s2.0-33747196725 08/23/2006       541 Citations
  • Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. (Gantner BN, Simmons RM, Underhill DM) EMBO J 2005 Mar 23;24(6):1277-86 PMID: 15729357 PMCID: PMC556398 SCOPUS ID: 2-s2.0-17144370549 02/25/2005       569 Citations
  • Integration of Toll-like receptor and phagocytic signaling for tailored immunity. (Underhill DM, Gantner B) Microbes Infect 2004 Dec;6(15):1368-73 PMID: 15596122 SCOPUS ID: 2-s2.0-16644380633 12/15/2004       130 Citations
  • Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. (Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM) J Exp Med 2003 May 05;197(9):1107-17 PMID: 12719479 PMCID: PMC2193968 SCOPUS ID: 2-s2.0-0038558249 04/30/2003       1430 Citations
  • Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. (Norment AM, Bogatzki LY, Gantner BN, Bevan MJ) J Immunol 2000 Jan 15;164(2):639-48 PMID: 10623805 SCOPUS ID: 2-s2.0-0034650922 01/07/2000       95 Citations
    • Last update: 12/17/2025