The recognition and surgical management of heritable lesions of the pancreas. Surg Oncol Clin N Am 2009 Jan;18(1):99-119, ix
Date
12/06/2008Pubmed ID
19056044DOI
10.1016/j.soc.2008.09.001Scopus ID
2-s2.0-56849108237 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Our knowledge regarding the inherited factors that lead to the development of lesions within the pancreas is clearly incomplete. This article addresses clinical issues in patients at moderate-to-high risk for pancreatic malignancy, with special emphasis on the recognition and diagnosis of known genetic syndromes. Using the current available information, the authors attempt to equip the practicing surgeon with critical information to increase clinical suspicion for heritable syndromes and inform specific surgical management. Additionally, this article is meant to encourage the practicing surgeon to participate in the genetic testing/screening, cancer surveillance, and prevention activities of patients who have heritable cancer syndromes and associated pancreatic lesions that require surgery.
Author List
Kim MP, Evans DB, Vu TM, Fleming JBAuthor
Douglas B. Evans MD Chair, Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Breast NeoplasmsColorectal Neoplasms, Hereditary Nonpolyposis
Dysplastic Nevus Syndrome
Female
Genes, Tumor Suppressor
Genetic Testing
Humans
Male
Pancreatic Neoplasms
Pancreatitis
Peutz-Jeghers Syndrome
Population Surveillance
von Hippel-Lindau Disease
