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Mesh term Neoplastic Syndromes, Hereditary

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Genetic Diseases, Inborn


The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance.

Browse to child terms:
Adenomatous Polyposis Coli
Basal Cell Nevus Syndrome
Birt-Hogg-Dube Syndrome
Colorectal Neoplasms, Hereditary Nonpolyposis
Dysplastic Nevus Syndrome
Exostoses, Multiple Hereditary
Hamartoma Syndrome, Multiple
Hereditary Breast and Ovarian Cancer Syndrome
Li-Fraumeni Syndrome
Multiple Endocrine Neoplasia
Peutz-Jeghers Syndrome
Tuberous Sclerosis
Wilms Tumor

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jenkins-FCD Prod-480 9a4deaf152b0b06dd18151814fff2e18f6c05280