Medical College of Wisconsin
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Daisy Sahoo PhD

Daisy Sahoo PhD profile photo picture

Vice Chair, Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Administration

Member of the Cancer Center
Member of the Cardiovascular Center


Publications (37)

  • Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses. (Chen Y, Yang M, Huang W, Chen W, Zhao Y, Schulte ML, Volberding P, Gerbec Z, Zimmermann MT, Zeighami A, Demos W, Zhang J, Knaack DA, Smith BC, Cui W, Malarkannan S, Sodhi K, Shapiro JI, Xie Z, Sahoo D, Silverstein RL) Circ Res 2019 12 06;125(12):1087-1102 PMID: 31625810 PMCID: PMC6921463 SCOPUS ID: 2-s2.0-85076330129 10/19/2019       8 Citations
  • Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease. (Rodriguez A, Trigatti BL, Mineo C, Knaack D, Wilkins JT, Sahoo D, Asztalos BF, Mora S, Cuchel M, Pownall HJ, Rosales C, Bernatchez P, Ribeiro Martins da Silva A, Getz GS, Barber JL, Shearer GC, Zivkovic AM, Tietge UJF, Sacks FM, Connelly MA, Oda MN, Davidson WS, Sorci-Thomas MG, Vaisar T, Ruotolo G, Vickers KC, Martel C) Arterioscler Thromb Vasc Biol 2019 12;39(12):2457-2467 PMID: 31597448 PMCID: PMC6937204 SCOPUS ID: 2-s2.0-85075813183 10/11/2019       1 Citation
  • Modification of HDL by reactive aldehydes alters select cardioprotective functions of HDL in macrophages. (Schill RL, Knaack DA, Powers HR, Chen Y, Yang M, Schill DJ, Silverstein RL, Sahoo D) FEBS J 2020 Feb;287(4):695-707 PMID: 31386799 PMCID: PMC7002295 SCOPUS ID: 2-s2.0-85070750063 08/07/2019    
  • Proline residues in scavenger receptor-BI's C-terminal region support efficient cholesterol transport. (Proudfoot SC, Sahoo D) Biochem J 2019 03 22;476(6):951-963 PMID: 30837308 PMCID: PMC6430181 SCOPUS ID: 2-s2.0-85063681808 03/07/2019    
  • Liver X Receptors Suppress Activity of Cholesterol and Fatty Acid Synthesis Pathways To Oppose Gammaherpesvirus Replication. (Lange PT, Schorl C, Sahoo D, Tarakanova VL) mBio 2018 07 17;9(4) PMID: 30018108 PMCID: PMC6050960 SCOPUS ID: 2-s2.0-85055540133 07/19/2018       8 Citations
  • Effect of adiposity on tissue-specific adiponectin secretion. (Reneau J, Goldblatt M, Gould J, Kindel T, Kastenmeier A, Higgins R, Rengel LR, Schoyer K, James R, Obi B, Moosreiner A, Nicholson K, Sahoo D, Kidambi S) PLoS One 2018;13(6):e0198889 PMID: 29924824 PMCID: PMC6010237 SCOPUS ID: 2-s2.0-85048771061 06/21/2018       6 Citations
  • Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling. (Dong L, Yuan Y, Opansky C, Chen Y, Aguilera-Barrantes I, Wu S, Yuan R, Cao Q, Cheng YC, Sahoo D, Silverstein RL, Ren B) Oncotarget 2017 Apr 04;8(14):22550-22562 PMID: 28186980 PMCID: PMC5410244 SCOPUS ID: 2-s2.0-85016933174 02/12/2017       11 Citations
  • NMR Structure of the C-Terminal Transmembrane Domain of the HDL Receptor, SR-BI, and a Functionally Relevant Leucine Zipper Motif. (Chadwick AC, Jensen DR, Hanson PJ, Lange PT, Proudfoot SC, Peterson FC, Volkman BF, Sahoo D) Structure 2017 03 07;25(3):446-457 PMID: 28162952 PMCID: PMC5575897 SCOPUS ID: 2-s2.0-85011284406 02/07/2017       4 Citations
  • Domain Mapping of Heat Shock Protein 70 Reveals That Glutamic Acid 446 and Arginine 447 Are Critical for Regulating Superoxide Dismutase 2 Function. (Afolayan AJ, Alexander M, Holme RL, Michalkiewicz T, Rana U, Teng RJ, Zemanovic S, Sahoo D, Pritchard KA Jr, Konduri GG) J Biol Chem 2017 02 10;292(6):2369-2378 PMID: 28028182 PMCID: PMC5313107 SCOPUS ID: 2-s2.0-85012108909 12/29/2016       4 Citations
  • Tryptophan 415 Is Critical for the Cholesterol Transport Functions of Scavenger Receptor BI. (Holme RL, Miller JJ, Nicholson K, Sahoo D) Biochemistry 2016 Jan 12;55(1):103-13 PMID: 26652912 PMCID: PMC5428993 SCOPUS ID: 2-s2.0-84954457161 12/15/2015       8 Citations
  • Oxidized LDL-bound CD36 recruits an Na⁺/K⁺-ATPase-Lyn complex in macrophages that promotes atherosclerosis. (Chen Y, Kennedy DJ, Ramakrishnan DP, Yang M, Huang W, Li Z, Xie Z, Chadwick AC, Sahoo D, Silverstein RL) Sci Signal 2015 Sep 08;8(393):ra91 PMID: 26350901 PMCID: PMC4852751 SCOPUS ID: 2-s2.0-84941034207 09/10/2015       39 Citations
  • Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress. (Korytowski W, Wawak K, Pabisz P, Schmitt JC, Chadwick AC, Sahoo D, Girotti AW) Arterioscler Thromb Vasc Biol 2015 Oct;35(10):2104-13 PMID: 26315403 PMCID: PMC4601804 SCOPUS ID: 2-s2.0-84942259316 09/01/2015       20 Citations
  • Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake. (Pollard RD, Blesso CN, Zabalawi M, Fulp B, Gerelus M, Zhu X, Lyons EW, Nuradin N, Francone OL, Li XA, Sahoo D, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2015 Jun 19;290(25):15496-511 PMID: 25947382 PMCID: PMC4505464 SCOPUS ID: 2-s2.0-84939623747 05/08/2015       14 Citations
  • Acrolein impairs the cholesterol transport functions of high density lipoproteins. (Chadwick AC, Holme RL, Chen Y, Thomas MJ, Sorci-Thomas MG, Silverstein RL, Pritchard KA Jr, Sahoo D) PLoS One 2015;10(4):e0123138 PMID: 25849485 PMCID: PMC4388475 SCOPUS ID: 2-s2.0-84927672521 04/08/2015       18 Citations
  • Inhibition of an NAD⁺ salvage pathway provides efficient and selective toxicity to human pluripotent stem cells. (Kropp EM, Oleson BJ, Broniowska KA, Bhattacharya S, Chadwick AC, Diers AR, Hu Q, Sahoo D, Hogg N, Boheler KR, Corbett JA, Gundry RL) Stem Cells Transl Med 2015 May;4(5):483-93 PMID: 25834119 PMCID: PMC4414215 SCOPUS ID: 2-s2.0-84930445700 04/03/2015       12 Citations
  • Identification and specification of the mouse skeletal stem cell. (Chan CK, Seo EY, Chen JY, Lo D, McArdle A, Sinha R, Tevlin R, Seita J, Vincent-Tompkins J, Wearda T, Lu WJ, Senarath-Yapa K, Chung MT, Marecic O, Tran M, Yan KS, Upton R, Walmsley GG, Lee AS, Sahoo D, Kuo CJ, Weissman IL, Longaker MT) Cell 2015 Jan 15;160(1-2):285-98 PMID: 25594184 PMCID: PMC4297645 01/17/2015       235 Citations
  • Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis. (Chadwick AC, Jensen DR, Peterson FC, Volkman BF, Sahoo D) Protein Expr Purif 2015 Mar;107:35-42 PMID: 25461971 PMCID: PMC4270826 SCOPUS ID: 2-s2.0-84916910193 12/03/2014       6 Citations
  • SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport. (Kartz GA, Holme RL, Nicholson K, Sahoo D) Biochemistry 2014 Oct 07;53(39):6173-82 PMID: 25211142 PMCID: PMC4188264 SCOPUS ID: 2-s2.0-84907829390 09/12/2014       21 Citations
  • Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks. (Chadwick AC, Sahoo D) Curr Opin Endocrinol Diabetes Obes 2013 Apr;20(2):124-31 PMID: 23403740 PMCID: PMC3967407 SCOPUS ID: 2-s2.0-84874949459 02/14/2013       10 Citations
  • Functional characterization of newly-discovered mutations in human SR-BI. (Chadwick AC, Sahoo D) PLoS One 2012;7(9):e45660 PMID: 23029167 PMCID: PMC3448639 SCOPUS ID: 2-s2.0-84866661659 10/03/2012       31 Citations
  • Cholesterol and lipoprotein dynamics in a hibernating mammal. (Otis JP, Sahoo D, Drover VA, Yen CL, Carey HV) PLoS One 2011;6(12):e29111 PMID: 22195001 PMCID: PMC3240636 SCOPUS ID: 2-s2.0-83455168928 12/24/2011       16 Citations
  • Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport. (Papale GA, Hanson PJ, Sahoo D) Biochemistry 2011 Jul 19;50(28):6245-54 PMID: 21675794 PMCID: PMC3940413 SCOPUS ID: 2-s2.0-79960208673 06/17/2011       18 Citations
  • Extracellular hydrophobic regions in scavenger receptor BI play a key role in mediating HDL-cholesterol transport. (Papale GA, Nicholson K, Hanson PJ, Pavlovic M, Drover VA, Sahoo D) Arch Biochem Biophys 2010 Apr 15;496(2):132-9 PMID: 20219439 PMCID: PMC2853188 SCOPUS ID: 2-s2.0-77951023562 03/12/2010       24 Citations
  • CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. (Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC) J Biol Chem 2008 May 09;283(19):13108-15 PMID: 18332148 PMCID: PMC2442355 SCOPUS ID: 2-s2.0-45149113087 03/12/2008       95 Citations
  • Scavenger receptor class B, type I (SR-BI) homo-dimerizes via its C-terminal region: fluorescence resonance energy transfer analysis. (Sahoo D, Peng Y, Smith JR, Darlington YF, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):818-29 PMID: 17556017 PMCID: PMC1993887 SCOPUS ID: 2-s2.0-34250214535 06/09/2007       28 Citations
  • The role of scavenger receptors in signaling, inflammation and atherosclerosis (Sahoo D, Drover VA) Biochemistry of Atherosclerosis 2006:70-91 SCOPUS ID: 2-s2.0-84900572318 12/01/2006    
  • Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers. (Sahoo D, Darlington YF, Pop D, Williams DL, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):807-17 PMID: 16624615 SCOPUS ID: 2-s2.0-34250028241 04/21/2006       33 Citations
  • CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. (Drover VA, Ajmal M, Nassir F, Davidson NO, Nauli AM, Sahoo D, Tso P, Abumrad NA) J Clin Invest 2005 May;115(5):1290-7 PMID: 15841205 PMCID: PMC1074677 SCOPUS ID: 2-s2.0-18244393432 04/21/2005       162 Citations
  • Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester. (Parathath S, Sahoo D, Darlington YF, Peng Y, Collins HL, Rothblat GH, Williams DL, Connelly MA) J Biol Chem 2004 Jun 11;279(24):24976-85 PMID: 15060063 SCOPUS ID: 2-s2.0-2942535969 04/03/2004       23 Citations
  • ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes. (Sahoo D, Trischuk TC, Chan T, Drover VA, Ho S, Chimini G, Agellon LB, Agnihotri R, Francis GA, Lehner R) J Lipid Res 2004 Jun;45(6):1122-31 PMID: 14993246 SCOPUS ID: 2-s2.0-2542484330 03/03/2004       69 Citations
  • Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity. (Boucher J, Ramsamy TA, Braschi S, Sahoo D, Neville TA, Sparks DL) J Lipid Res 2004 May;45(5):849-58 PMID: 14967812 SCOPUS ID: 2-s2.0-2142718234 02/18/2004       43 Citations
  • Lipid-triggered conformational switch of apolipophorin III helix bundle to an extended helix organization. (Sahoo D, Weers PM, Ryan RO, Narayanaswami V) J Mol Biol 2002 Aug 09;321(2):201-14 PMID: 12144779 SCOPUS ID: 2-s2.0-0036384368 07/30/2002       57 Citations
  • Pyrene excimer fluorescence: a spatially sensitive probe to monitor lipid-induced helical rearrangement of apolipophorin III. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) Biochemistry 2000 Jun 06;39(22):6594-601 PMID: 10828977 SCOPUS ID: 2-s2.0-0034612303 06/01/2000       106 Citations
  • NMR evidence for a conformational adaptation of apolipophorin III upon lipid association. (Wang J, Sahoo D, Sykes BD, Ryan RO) Biochem Cell Biol 1998;76(2-3):276-83 PMID: 9923696 SCOPUS ID: 2-s2.0-0032469624 01/29/1999       11 Citations
  • Fluorescence studies of exchangeable apolipoprotein-lipid interactions. Superficial association of apolipophorin III with lipoprotein surfaces. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) J Biol Chem 1998 Jan 16;273(3):1403-8 PMID: 9430675 SCOPUS ID: 2-s2.0-0031914422 01/27/1998       19 Citations
  • Fluorescence studies of protein-lipid interactions of apolipophorin III (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) FASEB Journal 1997;11(9) SCOPUS ID: 2-s2.0-33750239283 12/01/1997    
  • Multidimensional NMR studies of an exchangeable apolipoprotein and its interactions with lipids (Wang J, Sahoo D, Schieve D, Gagné SM, Sykes BD, Ryan RO) Techniques in Protein Chemistry 1997;8(C):427-438 SCOPUS ID: 2-s2.0-0000324098 12/01/1997    
  • Last update: 08/06/2020
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