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Francesca M. Marassi PhD

Chair, Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Administration

image of /images/ORCIDiD_icon16x16.png https://orcid.org/0000-0003-2695-5844

Member of the Cancer Center

I am willing to collaborate on research projects.
I am willing to mentor a junior faculty member.

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Publications (107)

Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite. (Gopinath T, Shin K, Tian Y, Im W, Struppe J, Perrone B, Hassan A, Marassi FM) J Struct Biol 2024 Mar;216(1):108061 PMID: 38185342 PMCID: PMC10939839 SCOPUS ID: 2-s2.0-85182378487 01/08/2024

Dynamic Nuclear Polarization Illuminates Key Protein-Lipid Interactions in the Native Bacterial Cell Envelope. (Kent JE, Ackermann BE, Debelouchina GT, Marassi FM) Biochemistry 2023 Aug 01;62(15):2252-2256 PMID: 37459255 PMCID: PMC11019665 SCOPUS ID: 2-s2.0-85166390720 07/17/2023 1 Citation

Dynamic nuclear polarization illuminates key protein-lipid interactions in the native bacterial cell envelope. (Kent JE, Ackermann BE, Debelouchina GT, Marassi FM) bioRxiv 2023 May 18 PMID: 37292594 PMCID: PMC10245764 06/09/2023

Vitronectin, the major regulator of age-related macular degeneration. (Shin K, Kent JE, Aleshin AE, Tian Y, Fujimoto LM, Singh C, Marassi FM) Biophys J 2023 Feb 10;122(3S1):467a PMID: 36784398 02/15/2023

Calcium-induced environmental adaptability of the blood protein vitronectin. (Tian Y, Shin K, Aleshin AE, Im W, Marassi FM) Biophys J 2022 Oct 18;121(20):3896-3906 PMID: 36056555 PMCID: PMC9674982 SCOPUS ID: 2-s2.0-85137693880 09/04/2022 2 Citations

A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis. (Zhang L, Kent JE, Whitaker M, Young DC, Herrmann D, Aleshin AE, Ko YH, Cingolani G, Saad JS, Moody DB, Marassi FM, Ehrt S, Niederweis M) Nat Commun 2022 Apr 26;13(1):2255 PMID: 35474308 PMCID: PMC9042941 SCOPUS ID: 2-s2.0-85128924949 04/28/2022 9 Citations

PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer. (Jeung HC, Puentes R, Aleshin A, Indarte M, Correa RG, Bankston LA, Layng FIAL, Ahmed Z, Wistuba I, Yao Y, Duenas DG, Zhang S, Meuillet EJ, Marassi F, Liddington RC, Kirkpatrick L, Powis G) Exp Cell Res 2021 Dec 15;409(2):112930 PMID: 34800542 PMCID: PMC8925131 SCOPUS ID: 2-s2.0-85119376654 11/21/2021 1 Citation

Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids. (Aleshin AE, Yao Y, Iftikhar A, Bobkov AA, Yu J, Cadwell G, Klein MG, Dong C, Bankston LA, Liddington RC, Im W, Powis G, Marassi FM) Structure 2021 Sep 02;29(9):1029-1039.e3 PMID: 33878292 PMCID: PMC8419008 SCOPUS ID: 2-s2.0-85107072903 04/21/2021 13 Citations

Correlating the Structure and Activity of Y. pestis Ail in a Bacterial Cell Envelope. (Kent JE, Fujimoto LM, Shin K, Singh C, Yao Y, Park SH, Opella SJ, Plano GV, Marassi FM) Biophys J 2021 Feb 02;120(3):453-462 PMID: 33359463 PMCID: PMC7895992 SCOPUS ID: 2-s2.0-85099124668 12/29/2020 5 Citations

Conformational States of the Cytoprotective Protein Bcl-xL. (Ryzhov P, Tian Y, Yao Y, Bobkov AA, Im W, Marassi FM) Biophys J 2020 Oct 06;119(7):1324-1334 PMID: 32888404 PMCID: PMC7567986 SCOPUS ID: 2-s2.0-85090205653 09/06/2020 8 Citations

Calcium and hydroxyapatite binding site of human vitronectin provides insights to abnormal deposit formation. (Shin K, Kent JE, Singh C, Fujimoto LM, Yu J, Tian Y, Im W, Marassi FM) Proc Natl Acad Sci U S A 2020 Aug 04;117(31):18504-18510 PMID: 32699145 PMCID: PMC7414086 SCOPUS ID: 2-s2.0-85089166480 07/24/2020 11 Citations

Mutually constructive roles of Ail and LPS in Yersinia pestis serum survival. (Singh C, Lee H, Tian Y, Schesser Bartra S, Hower S, Fujimoto LM, Yao Y, Ivanov SA, Shaikhutdinova RZ, Anisimov AP, Plano GV, Im W, Marassi FM) Mol Microbiol 2020 Sep;114(3):510-520 PMID: 32462782 PMCID: PMC7594906 SCOPUS ID: 2-s2.0-85087207600 05/29/2020 14 Citations

Membrane proteins in magnetically aligned phospholipid polymer discs for solid-state NMR spectroscopy. (Park SH, Wu J, Yao Y, Singh C, Tian Y, Marassi FM, Opella SJ) Biochim Biophys Acta Biomembr 2020 Sep 01;1862(9):183333 PMID: 32371072 PMCID: PMC8370186 SCOPUS ID: 2-s2.0-85085078836 05/07/2020 15 Citations

Structure of human Vitronectin C-terminal domain and interaction with Yersinia pestis outer membrane protein Ail. (Shin K, Lechtenberg BC, Fujimoto LM, Yao Y, Bartra SS, Plano GV, Marassi FM) Sci Adv 2019 Sep;5(9):eaax5068 PMID: 31535027 PMCID: PMC6739113 SCOPUS ID: 2-s2.0-85072215989 09/20/2019 17 Citations

Reconstitution and Characterization of BCL-2 Family Proteins in Lipid Bilayer Nanodiscs. (Yao Y, Marassi FM) Methods Mol Biol 2019;1877:233-246 PMID: 30536010 PMCID: PMC6599400 SCOPUS ID: 2-s2.0-85058604297 12/12/2018 9 Citations

Lipoprotein Particle Formation by Proapoptotic tBid. (Ekanayake V, Nisan D, Ryzhov P, Yao Y, Marassi FM) Biophys J 2018 Aug 07;115(3):533-542 PMID: 30017071 PMCID: PMC6084415 SCOPUS ID: 2-s2.0-85049787082 07/19/2018 2 Citations

Regulation of apoptosis by an intrinsically disordered region of Bcl-xL. (Follis AV, Llambi F, Kalkavan H, Yao Y, Phillips AH, Park CG, Marassi FM, Green DR, Kriwacki RW) Nat Chem Biol 2018 May;14(5):458-465 PMID: 29507390 PMCID: PMC5899648 SCOPUS ID: 2-s2.0-85042854185 03/07/2018 39 Citations

Structure of monomeric Interleukin-8 and its interactions with the N-terminal Binding Site-I of CXCR1 by solution NMR spectroscopy. (Berkamp S, Park SH, De Angelis AA, Marassi FM, Opella SJ) J Biomol NMR 2017 Nov;69(3):111-121 PMID: 29143165 PMCID: PMC5869024 SCOPUS ID: 2-s2.0-85034031500 11/17/2017 27 Citations

Structural Insights into the Yersinia pestis Outer Membrane Protein Ail in Lipid Bilayers. (Dutta SK, Yao Y, Marassi FM) J Phys Chem B 2017 Aug 17;121(32):7561-7570 PMID: 28726410 PMCID: PMC5713880 SCOPUS ID: 2-s2.0-85030760401 07/21/2017 22 Citations

Applications of NMR to membrane proteins. (Opella SJ, Marassi FM) Arch Biochem Biophys 2017 Aug 15;628:92-101 PMID: 28529197 PMCID: PMC5657258 SCOPUS ID: 2-s2.0-85019639870 05/23/2017 59 Citations

High resolution solid-state NMR spectroscopy of the Yersinia pestis outer membrane protein Ail in lipid membranes. (Yao Y, Dutta SK, Park SH, Rai R, Fujimoto LM, Bobkov AA, Opella SJ, Marassi FM) J Biomol NMR 2017 Mar;67(3):179-190 PMID: 28239773 PMCID: PMC5490241 SCOPUS ID: 2-s2.0-85013992133 02/28/2017 13 Citations

High quality NMR structures: a new force field with implicit water and membrane solvation for Xplor-NIH. (Tian Y, Schwieters CD, Opella SJ, Marassi FM) J Biomol NMR 2017 Jan;67(1):35-49 PMID: 28035651 PMCID: PMC5487259 SCOPUS ID: 2-s2.0-85007506858 12/31/2016 23 Citations

Orphan Nuclear Receptor NR4A1 Binds a Novel Protein Interaction Site on Anti-apoptotic B Cell Lymphoma Gene 2 Family Proteins. (Godoi PHC, Wilkie-Grantham RP, Hishiki A, Sano R, Matsuzawa Y, Yanagi H, Munte CE, Chen Y, Yao Y, Marassi FM, Kalbitzer HR, Matsuzawa SI, Reed JC) J Biol Chem 2016 Jul 01;291(27):14072-14084 PMID: 27129202 PMCID: PMC4933167 SCOPUS ID: 2-s2.0-84976625451 04/30/2016 15 Citations

Characterization of the membrane-inserted C-terminus of cytoprotective BCL-XL. (Yao Y, Nisan D, Fujimoto LM, Antignani A, Barnes A, Tjandra N, Youle RJ, Marassi FM) Protein Expr Purif 2016 Jun;122:56-63 PMID: 26923059 PMCID: PMC4842142 SCOPUS ID: 2-s2.0-84959457496 03/01/2016 20 Citations

Yersinia pestis uses the Ail outer membrane protein to recruit vitronectin. (Bartra SS, Ding Y, Miya Fujimoto L, Ring JG, Jain V, Ram S, Marassi FM, Plano GV) Microbiology (Reading) 2015 Nov;161(11):2174-2183 PMID: 26377177 PMCID: PMC4806588 SCOPUS ID: 2-s2.0-84947218568 09/18/2015 21 Citations

A Practical Implicit Membrane Potential for NMR Structure Calculations of Membrane Proteins. (Tian Y, Schwieters CD, Opella SJ, Marassi FM) Biophys J 2015 Aug 04;109(3):574-85 PMID: 26244739 PMCID: PMC4572468 SCOPUS ID: 2-s2.0-84938487475 08/06/2015 21 Citations

Backbone structure of Yersinia pestis Ail determined in micelles by NMR-restrained simulated annealing with implicit membrane solvation. (Marassi FM, Ding Y, Schwieters CD, Tian Y, Yao Y) J Biomol NMR 2015 Sep;63(1):59-65 PMID: 26143069 PMCID: PMC4577439 SCOPUS ID: 2-s2.0-84942374186 07/06/2015 20 Citations

Solid-State NMR-Restrained Ensemble Dynamics of a Membrane Protein in Explicit Membranes. (Cheng X, Jo S, Qi Y, Marassi FM, Im W) Biophys J 2015 Apr 21;108(8):1954-62 PMID: 25902435 PMCID: PMC4407261 SCOPUS ID: 2-s2.0-84928230032 04/23/2015 10 Citations

Conformation of BCL-XL upon Membrane Integration. (Yao Y, Fujimoto LM, Hirshman N, Bobkov AA, Antignani A, Youle RJ, Marassi FM) J Mol Biol 2015 Jul 03;427(13):2262-70 PMID: 25731750 PMCID: PMC4457587 SCOPUS ID: 2-s2.0-84930085953 03/04/2015 49 Citations

Solid-state NMR of the Yersinia pestis outer membrane protein Ail in lipid bilayer nanodiscs sedimented by ultracentrifugation. (Ding Y, Fujimoto LM, Yao Y, Marassi FM) J Biomol NMR 2015 Apr;61(3-4):275-86 PMID: 25578899 PMCID: PMC4398618 SCOPUS ID: 2-s2.0-84939979655 01/13/2015 25 Citations

Influence of the lipid membrane environment on structure and activity of the outer membrane protein Ail from Yersinia pestis. (Ding Y, Fujimoto LM, Yao Y, Plano GV, Marassi FM) Biochim Biophys Acta 2015 Feb;1848(2):712-20 PMID: 25433311 PMCID: PMC4281492 SCOPUS ID: 2-s2.0-84915758524 11/30/2014 27 Citations

Structure of the membrane protein MerF, a bacterial mercury transporter, improved by the inclusion of chemical shift anisotropy constraints. (Tian Y, Lu GJ, Marassi FM, Opella SJ) J Biomol NMR 2014 Sep;60(1):67-71 PMID: 25103921 PMCID: PMC4154067 SCOPUS ID: 2-s2.0-84929129611 08/12/2014 17 Citations

Structure of the Na,K-ATPase regulatory protein FXYD2b in micelles: implications for membrane-water interfacial arginines. (Gong XM, Ding Y, Yu J, Yao Y, Marassi FM) Biochim Biophys Acta 2015 Jan;1848(1 Pt B):299-306 PMID: 24794573 PMCID: PMC4216782 SCOPUS ID: 2-s2.0-84979866882 05/06/2014 9 Citations

A practical implicit solvent potential for NMR structure calculation. (Tian Y, Schwieters CD, Opella SJ, Marassi FM) J Magn Reson 2014 Jun;243:54-64 PMID: 24747742 PMCID: PMC4037354 SCOPUS ID: 2-s2.0-84898953449 04/22/2014 37 Citations

The rheostat in the membrane: BCL-2 family proteins and apoptosis. (Volkmann N, Marassi FM, Newmeyer DD, Hanein D) Cell Death Differ 2014 Feb;21(2):206-15 PMID: 24162659 PMCID: PMC3890954 SCOPUS ID: 2-s2.0-84892422163 10/29/2013 190 Citations

Membrane protein structure determination in membrana. (Ding Y, Yao Y, Marassi FM) Acc Chem Res 2013 Sep 17;46(9):2182-90 PMID: 24041243 PMCID: PMC3970975 SCOPUS ID: 2-s2.0-84884224184 09/18/2013 27 Citations

Membrane protein structure determination: back to the membrane. (Yao Y, Ding Y, Tian Y, Opella SJ, Marassi FM) Methods Mol Biol 2013;1063:145-58 PMID: 23975776 PMCID: PMC4012560 SCOPUS ID: 2-s2.0-84884197877 08/27/2013 9 Citations

NMR-based simulation studies of Pf1 coat protein in explicit membranes. (Cheng X, Jo S, Marassi FM, Im W) Biophys J 2013 Aug 06;105(3):691-8 PMID: 23931317 PMCID: PMC3736739 SCOPUS ID: 2-s2.0-84881456818 08/13/2013 20 Citations

The structure of the mercury transporter MerF in phospholipid bilayers: a large conformational rearrangement results from N-terminal truncation. (Lu GJ, Tian Y, Vora N, Marassi FM, Opella SJ) J Am Chem Soc 2013 Jun 26;135(25):9299-302 PMID: 23763519 PMCID: PMC3763827 SCOPUS ID: 2-s2.0-84879528022 06/15/2013 29 Citations

The discreet charm of the curve. (Marassi FM) Biophys J 2013 Mar 19;104(6):1215-6 PMID: 23528078 PMCID: PMC3602748 SCOPUS ID: 2-s2.0-84877023975 03/27/2013 3 Citations

Structure of the chemokine receptor CXCR1 in phospholipid bilayers. (Park SH, Das BB, Casagrande F, Tian Y, Nothnagel HJ, Chu M, Kiefer H, Maier K, De Angelis AA, Marassi FM, Opella SJ) Nature 2012 Nov 29;491(7426):779-83 PMID: 23086146 PMCID: PMC3700570 SCOPUS ID: 2-s2.0-84870290491 10/23/2012 394 Citations

Improved chemical shift prediction by Rosetta conformational sampling. (Tian Y, Opella SJ, Marassi FM) J Biomol NMR 2012 Nov;54(3):237-43 PMID: 23007199 PMCID: PMC3484222 SCOPUS ID: 2-s2.0-84868205509 09/26/2012 6 Citations

Structure determination of a membrane protein in proteoliposomes. (Das BB, Nothnagel HJ, Lu GJ, Son WS, Tian Y, Marassi FM, Opella SJ) J Am Chem Soc 2012 Feb 01;134(4):2047-56 PMID: 22217388 PMCID: PMC3272072 SCOPUS ID: 2-s2.0-84856484347 01/06/2012 78 Citations

Molecular structure and peptidoglycan recognition of Mycobacterium tuberculosis ArfA (Rv0899). (Yao Y, Barghava N, Kim J, Niederweis M, Marassi FM) J Mol Biol 2012 Feb 17;416(2):208-20 PMID: 22206986 PMCID: PMC3269530 SCOPUS ID: 2-s2.0-84856438110 12/31/2011 15 Citations

AssignFit: a program for simultaneous assignment and structure refinement from solid-state NMR spectra. (Tian Y, Schwieters CD, Opella SJ, Marassi FM) J Magn Reson 2012 Jan;214(1):42-50 PMID: 22036904 PMCID: PMC3257385 SCOPUS ID: 2-s2.0-84855687118 11/01/2011 17 Citations

Structure determination of membrane proteins in five easy pieces. (Marassi FM, Das BB, Lu GJ, Nothnagel HJ, Park SH, Son WS, Tian Y, Opella SJ) Methods 2011 Dec;55(4):363-9 PMID: 21964394 PMCID: PMC3264820 SCOPUS ID: 2-s2.0-84855993501 10/04/2011 25 Citations

Mycobacterium tuberculosis Rv0899 defines a family of membrane proteins widespread in nitrogen-fixing bacteria. (Marassi FM) Proteins 2011 Oct;79(10):2946-55 PMID: 21905117 PMCID: PMC3172613 SCOPUS ID: 2-s2.0-80052576378 09/10/2011 3 Citations

FXYD proteins reverse inhibition of the Na+-K+ pump mediated by glutathionylation of its beta1 subunit. (Bibert S, Liu CC, Figtree GA, Garcia A, Hamilton EJ, Marassi FM, Sweadner KJ, Cornelius F, Geering K, Rasmussen HH) J Biol Chem 2011 May 27;286(21):18562-72 PMID: 21454534 PMCID: PMC3099672 SCOPUS ID: 2-s2.0-79956297624 04/02/2011 75 Citations

Expression, refolding, and initial structural characterization of the Y. pestis Ail outer membrane protein in lipids. (Plesniak LA, Mahalakshmi R, Rypien C, Yang Y, Racic J, Marassi FM) Biochim Biophys Acta 2011 Jan;1808(1):482-9 PMID: 20883662 PMCID: PMC2997907 SCOPUS ID: 2-s2.0-78649779510 10/05/2010 18 Citations

Structure and dynamics of the membrane-bound form of Pf1 coat protein: implications of structural rearrangement for virus assembly. (Park SH, Marassi FM, Black D, Opella SJ) Biophys J 2010 Sep 08;99(5):1465-74 PMID: 20816058 PMCID: PMC2931714 SCOPUS ID: 2-s2.0-77956582409 09/08/2010 64 Citations

Structure and activity of CPNGRC: a modified CD13/APN peptidic homing motif. (Plesniak LA, Salzameda B, Hinderberger H, Regan E, Kahn J, Mills SA, Teriete P, Yao Y, Jennings P, Marassi F, Adams JA) Chem Biol Drug Des 2010 Jun;75(6):551-62 PMID: 20374250 PMCID: PMC2890305 SCOPUS ID: 2-s2.0-77951957141 04/09/2010 17 Citations

Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel. (Teriete P, Yao Y, Kolodzik A, Yu J, Song H, Niederweis M, Marassi FM) Biochemistry 2010 Apr 06;49(13):2768-77 PMID: 20199110 PMCID: PMC2847638 SCOPUS ID: 2-s2.0-84891371714 03/05/2010 25 Citations

BAX and BAK caught in the act. (Yao Y, Marassi FM) Mol Cell 2009 Nov 13;36(3):353-4 PMID: 19917244 PMCID: PMC2897738 SCOPUS ID: 2-s2.0-70449108075 11/18/2009 4 Citations

Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1. (Teriete P, Thai K, Choi J, Marassi FM) Biochim Biophys Acta 2009 Nov;1788(11):2462-70 PMID: 19761758 PMCID: PMC2778042 SCOPUS ID: 2-s2.0-71149085579 09/19/2009 19 Citations

Mapping the interaction of pro-apoptotic tBID with pro-survival BCL-XL. (Yao Y, Bobkov AA, Plesniak LA, Marassi FM) Biochemistry 2009 Sep 15;48(36):8704-11 PMID: 19670908 PMCID: PMC2762941 SCOPUS ID: 2-s2.0-70149111283 08/13/2009 27 Citations

Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes. (Diller A, Loudet C, Aussenac F, Raffard G, Fournier S, Laguerre M, Grélard A, Opella SJ, Marassi FM, Dufourc EJ) Biochimie 2009 Jun;91(6):744-51 PMID: 19248817 PMCID: PMC2899883 SCOPUS ID: 2-s2.0-67349086597 03/03/2009 97 Citations

Orientation of the Escherichia coli outer membrane protein OmpX in phospholipid bilayer membranes determined by solid-State NMR. (Mahalakshmi R, Marassi FM) Biochemistry 2008 Jun 24;47(25):6531-8 PMID: 18512961 PMCID: PMC2899889 SCOPUS ID: 2-s2.0-45749128574 06/03/2008 47 Citations

Solid-state NMR spectroscopy of a membrane protein in biphenyl phospholipid bicelles with the bilayer normal parallel to the magnetic field. (Park SH, Loudet C, Marassi FM, Dufourc EJ, Opella SJ) J Magn Reson 2008 Jul;193(1):133-8 PMID: 18492613 PMCID: PMC2562692 SCOPUS ID: 2-s2.0-44649202072 05/22/2008 44 Citations

Competitive interactions of collagen and a jararhagin-derived disintegrin peptide with the integrin alpha2-I domain. (Lambert LJ, Bobkov AA, Smith JW, Marassi FM) J Biol Chem 2008 Jun 13;283(24):16665-72 PMID: 18417478 PMCID: PMC2423259 SCOPUS ID: 2-s2.0-47749137426 04/18/2008 18 Citations

Membrane orientation of the Na,K-ATPase regulatory membrane protein CHIF determined by solid-state NMR. (Franzin CM, Teriete P, Marassi FM) Magn Reson Chem 2007 Dec;45 Suppl 1(Suppl 1):S192-7 PMID: 18098352 PMCID: PMC2920893 SCOPUS ID: 2-s2.0-38849201806 12/22/2007 3 Citations

Structures of the FXYD regulatory proteins in lipid micelles and membranes. (Franzin CM, Gong XM, Teriete P, Marassi FM) J Bioenerg Biomembr 2007 Dec;39(5-6):379-83 PMID: 18000745 PMCID: PMC2917602 SCOPUS ID: 2-s2.0-38349140152 11/15/2007 25 Citations

Nuclear magnetic resonance structural studies of membrane proteins in micelles and bilayers. (Gong XM, Franzin CM, Thai K, Yu J, Marassi FM) Methods Mol Biol 2007;400:515-29 PMID: 17951757 PMCID: PMC2918260 SCOPUS ID: 2-s2.0-36549056082 10/24/2007 17 Citations

Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid. (Choi J, Zhai D, Zhou X, Satterthwait A, Reed JC, Marassi FM) Chem Biol Drug Des 2007 Nov;70(5):383-92 PMID: 17927731 PMCID: PMC2917600 SCOPUS ID: 2-s2.0-35348952538 10/12/2007 18 Citations

NMR structural studies of the bacterial outer membrane protein OmpX in oriented lipid bilayer membranes. (Mahalakshmi R, Franzin CM, Choi J, Marassi FM) Biochim Biophys Acta 2007 Dec;1768(12):3216-24 PMID: 17916325 PMCID: PMC2369366 SCOPUS ID: 2-s2.0-36849038917 10/06/2007 27 Citations

Structural similarity of a membrane protein in micelles and membranes. (Franzin CM, Teriete P, Marassi FM) J Am Chem Soc 2007 Jul 04;129(26):8078-9 PMID: 17567018 PMCID: PMC2518691 SCOPUS ID: 2-s2.0-34447135010 06/15/2007 47 Citations

Structure of the Na,K-ATPase regulatory protein FXYD1 in micelles. (Teriete P, Franzin CM, Choi J, Marassi FM) Biochemistry 2007 Jun 12;46(23):6774-83 PMID: 17511473 PMCID: PMC2527028 SCOPUS ID: 2-s2.0-34250176566 05/22/2007 64 Citations

NMR of membrane proteins in micelles and bilayers: the FXYD family proteins. (Franzin CM, Gong XM, Thai K, Yu J, Marassi FM) Methods 2007 Apr;41(4):398-408 PMID: 17367712 PMCID: PMC2920895 SCOPUS ID: 2-s2.0-33947171594 03/21/2007 36 Citations

Membrane Proteins (Opella SJ, Marassi FM) eMagRes 2007;2007 SCOPUS ID: 2-s2.0-85122334166 01/01/2007

The anti-angiogenic peptide anginex disrupts the cell membrane. (Pilch J, Franzin CM, Knowles LM, Ferrer FJ, Marassi FM, Ruoslahti E) J Mol Biol 2006 Mar 03;356(4):876-85 PMID: 16403516 PMCID: PMC2922962 SCOPUS ID: 2-s2.0-31344438707 01/13/2006 17 Citations

NMR Structure Determination of Proteins in Bilayer Lipid Membranes: The FXYD Family Proteins (Franzin CM, Marassi FM) Advances in Planar Lipid Bilayers and Liposomes 2005;2(C):77-93 SCOPUS ID: 2-s2.0-28444458941 12/01/2005 3 Citations

Correlation of gene and protein structures in the FXYD family proteins. (Franzin CM, Yu J, Thai K, Choi J, Marassi FM) J Mol Biol 2005 Dec 09;354(4):743-50 PMID: 16288923 PMCID: PMC2907130 SCOPUS ID: 2-s2.0-28444456326 11/18/2005 14 Citations

Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation. (Rembold CM, Ripley ML, Meeks MK, Geddis LM, Kutchai HC, Marassi FM, Cheung JY, Moorman JR) J Vasc Res 2005;42(6):483-91 PMID: 16155364 PMCID: PMC1266286 SCOPUS ID: 2-s2.0-27344444876 09/13/2005 28 Citations

Bcl-XL as a fusion protein for the high-level expression of membrane-associated proteins. (Thai K, Choi J, Franzin CM, Marassi FM) Protein Sci 2005 Apr;14(4):948-55 PMID: 15741345 PMCID: PMC2253446 SCOPUS ID: 2-s2.0-15244346256 03/03/2005 20 Citations

Nuclear magnetic resonance structural studies of the FXYD family membrane proteins in lipid bilayers (Franzin CM, Yu J, Marassi FM) NMR Spectroscopy of Biological Solids 1 January 2005:191-214 SCOPUS ID: 2-s2.0-36849095399 01/01/2005 2 Citations

Structure determination of membrane proteins by NMR spectroscopy. (Opella SJ, Marassi FM) Chem Rev 2004 Aug;104(8):3587-606 PMID: 15303829 PMCID: PMC3270942 SCOPUS ID: 2-s2.0-4344704702 08/12/2004 373 Citations

Conformation of membrane-associated proapoptotic tBid. (Gong XM, Choi J, Franzin CM, Zhai D, Reed JC, Marassi FM) J Biol Chem 2004 Jul 09;279(28):28954-60 PMID: 15123718 PMCID: PMC3033194 SCOPUS ID: 2-s2.0-3142713275 05/05/2004 58 Citations

Structural studies of apoptosis and ion transport regulatory proteins in membranes. (Franzin CM, Choi J, Zhai D, Reed JC, Marassi FM) Magn Reson Chem 2004 Feb;42(2):172-9 PMID: 14745797 PMCID: PMC3033199 SCOPUS ID: 2-s2.0-0842264375 01/28/2004 41 Citations

Dipolar waves map the structure and topology of helices in membrane proteins. (Mesleh MF, Lee S, Veglia G, Thiriot DS, Marassi FM, Opella SJ) J Am Chem Soc 2003 Jul 23;125(29):8928-35 PMID: 12862490 PMCID: PMC3272074 SCOPUS ID: 2-s2.0-0037960787 07/17/2003 90 Citations

Utilizing NMR to study the structure of growth-inhibitory proteins. (Marassi F) Methods Mol Biol 2003;223:3-15 PMID: 12777716 PMCID: PMC3274346 06/05/2003

Hydration-optimized oriented phospholipid bilayer samples for solid-state NMR structural studies of membrane proteins. (Marassi FM, Crowell KJ) J Magn Reson 2003 Mar;161(1):64-9 PMID: 12660112 PMCID: PMC3033728 SCOPUS ID: 2-s2.0-0042994281 03/28/2003 34 Citations

Simultaneous assignment and structure determination of a membrane protein from NMR orientational restraints. (Marassi FM, Opella SJ) Protein Sci 2003 Mar;12(3):403-11 PMID: 12592011 PMCID: PMC2312444 SCOPUS ID: 2-s2.0-0037372352 02/20/2003 167 Citations

Expression and characterization of the FXYD ion transport regulators for NMR structural studies in lipid micelles and lipid bilayers. (Crowell KJ, Franzin CM, Koltay A, Lee S, Lucchese AM, Snyder BC, Marassi FM) Biochim Biophys Acta 2003 Jan 31;1645(1):15-21 PMID: 12535606 PMCID: PMC2917601 SCOPUS ID: 2-s2.0-0037474272 01/22/2003 19 Citations

Structure determination of membrane proteins by NMR spectroscopy. (Opella SJ, Nevzorov A, Mesleh MF, Marassi FM) Biochem Cell Biol 2002;80(5):597-604 PMID: 12440700 PMCID: PMC3454473 SCOPUS ID: 2-s2.0-0036968507 11/21/2002 58 Citations

Using pisa pies to resolve ambiguities in angular constraints from PISEMA spectra of aligned proteins. (Marassi FM, Opella SJ) J Biomol NMR 2002 Jul;23(3):239-42 PMID: 12238596 PMCID: PMC2920879 SCOPUS ID: 2-s2.0-0036361158 09/20/2002 25 Citations

NMR of peptides and proteins in oriented membranes (Marassi FM) Concepts in Magnetic Resonance Part A: Bridging Education and Research July 2002;14(3):212-224 SCOPUS ID: 2-s2.0-0013039776 07/01/2002 35 Citations

Dipolar waves as NMR maps of protein structure. (Mesleh MF, Veglia G, DeSilva TM, Marassi FM, Opella SJ) J Am Chem Soc 2002 Apr 24;124(16):4206-7 PMID: 11960438 PMCID: PMC3272071 SCOPUS ID: 2-s2.0-0037165693 04/19/2002 99 Citations

Expression, purification, and activities of full-length and truncated versions of the integral membrane protein Vpu from HIV-1. (Ma C, Marassi FM, Jones DH, Straus SK, Bour S, Strebel K, Schubert U, Oblatt-Montal M, Montal M, Opella SJ) Protein Sci 2002 Mar;11(3):546-57 PMID: 11847278 PMCID: PMC2373459 SCOPUS ID: 2-s2.0-0036181837 02/16/2002 105 Citations

Structure and topology of a peptide segment of the 6th transmembrane domain of the Saccharomyces cerevisae alpha-factor receptor in phospholipid bilayers. (Valentine KG, Liu SF, Marassi FM, Veglia G, Opella SJ, Ding FX, Wang SH, Arshava B, Becker JM, Naider F) Biopolymers 2001 Oct 05;59(4):243-56 PMID: 11473349 PMCID: PMC3282060 SCOPUS ID: 2-s2.0-0035813019 07/27/2001 43 Citations

Nuclear magnetic resonance of membrane-associated peptides and proteins. (Opella SJ, Ma C, Marassi FM) Methods Enzymol 2001;339:285-313 PMID: 11462817 PMCID: PMC3282062 SCOPUS ID: 2-s2.0-0034926431 07/21/2001 76 Citations

A simple approach to membrane protein secondary structure and topology based on NMR spectroscopy. (Marassi FM) Biophys J 2001 Feb;80(2):994-1003 PMID: 11159466 PMCID: PMC1301297 SCOPUS ID: 2-s2.0-0035142956 02/13/2001 69 Citations

Three-dimensional solid-state NMR spectroscopy is essential for resolution of resonances from in-plane residues in uniformly (15)N-labeled helical membrane proteins in oriented lipid bilayers. (Marassi FM, Ma C, Gesell JJ, Opella SJ) J Magn Reson 2000 May;144(1):156-61 PMID: 10783286 SCOPUS ID: 2-s2.0-0034183383 04/28/2000 64 Citations

A solid-state NMR index of helical membrane protein structure and topology. (Marassi FM, Opella SJ) J Magn Reson 2000 May;144(1):150-5 PMID: 10783285 PMCID: PMC3437921 SCOPUS ID: 2-s2.0-0034186215 04/28/2000 308 Citations

Orientation of cecropin A helices in phospholipid bilayers determined by solid-state NMR spectroscopy. (Marassi FM, Opella SJ, Juvvadi P, Merrifield RB) Biophys J 1999 Dec;77(6):3152-5 PMID: 10585936 PMCID: PMC1300585 SCOPUS ID: 2-s2.0-0032763732 12/10/1999 81 Citations

Correlation of the structural and functional domains in the membrane protein Vpu from HIV-1. (Marassi FM, Ma C, Gratkowski H, Straus SK, Strebel K, Oblatt-Montal M, Montal M, Opella SJ) Proc Natl Acad Sci U S A 1999 Dec 07;96(25):14336-41 PMID: 10588706 PMCID: PMC24437 SCOPUS ID: 2-s2.0-0033459562 12/10/1999 152 Citations

Dilute spin-exchange assignment of solid-state NMR spectra of oriented proteins: acetylcholine M2 in bilayers. (Marassi FM, Gesell JJ, Valente AP, Kim Y, Oblatt-Montal M, Montal M, Opella SJ) J Biomol NMR 1999 Jun;14(2):141-8 PMID: 10427741 PMCID: PMC3282054 SCOPUS ID: 2-s2.0-0033059428 07/31/1999 45 Citations

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. (Opella SJ, Marassi FM, Gesell JJ, Valente AP, Kim Y, Oblatt-Montal M, Montal M) Nat Struct Biol 1999 Apr;6(4):374-9 PMID: 10201407 PMCID: PMC3282055 SCOPUS ID: 2-s2.0-0032919444 04/14/1999 303 Citations

The roles of homonuclear line narrowing and the¹H amide chemical shift tensor in structure determination of proteins by solid-state NMR spectroscopy (Marassi FM, Ma C, Gesell JJ, Opella SJ) Applied Magnetic Resonance 1999;17(2-3):433-447 SCOPUS ID: 2-s2.0-19044399668 01/01/1999 10 Citations

NMR structural studies of membrane proteins. (Marassi FM, Opella SJ) Curr Opin Struct Biol 1998 Oct;8(5):640-8 PMID: 9818270 PMCID: PMC3282058 SCOPUS ID: 2-s2.0-0031764019 11/18/1998 138 Citations

Structural studies of the pore-lining segments of neurotransmitter-gated channels (Opella SJ, Gesell J, Valente AP, Marassi FM, Oblatt-Montal M, Sun W, Ferrer-Montiel A, Montal M) Chemtracts 1997;10(3):153-174 SCOPUS ID: 2-s2.0-0000571702 12/01/1997 18 Citations

Complete resolution of the solid-state NMR spectrum of a uniformly 15N-labeled membrane protein in phospholipid bilayers. (Marassi FM, Ramamoorthy A, Opella SJ) Proc Natl Acad Sci U S A 1997 Aug 05;94(16):8551-6 PMID: 9238014 PMCID: PMC23006 SCOPUS ID: 2-s2.0-0030844584 08/05/1997 198 Citations

Three-dimensional solid-state NMR spectroscopy of a peptide oriented in membrane bilayers. (Ramamoorthy A, Marassi FM, Zasloff M, Opella SJ) J Biomol NMR 1995 Nov;6(3):329-34 PMID: 8520224 PMCID: PMC3282056 SCOPUS ID: 2-s2.0-0029398795 11/01/1995 74 Citations

Resolving the two monolayers of a lipid bilayer in giant unilamellar vesicles using deuterium nuclear magnetic resonance. (Marassi FM, Shivers RR, Macdonald PM) Biochemistry 1993 Sep 28;32(38):9936-43 PMID: 8399163 SCOPUS ID: 2-s2.0-0027385040 09/28/1993 17 Citations

Influence of lipid lateral distribution on the surface charge response of the phosphatidylcholine headgroup as detected using 2H nuclear magnetic resonance. (Marassi FM, Djukic S, Macdonald PM) Biochim Biophys Acta 1993 Mar 14;1146(2):219-28 PMID: 8452858 SCOPUS ID: 2-s2.0-0027400684 03/14/1993 11 Citations

Response of the phosphatidylcholine headgroup to membrane surface charge in ternary mixtures of neutral, cationic, and anionic lipids: a deuterium NMR study. (Marassi FM, Macdonald PM) Biochemistry 1992 Oct 20;31(41):10031-6 PMID: 1390761 SCOPUS ID: 2-s2.0-0026803013 10/20/1992 43 Citations

Response of the headgroup of phosphatidylglycerol to membrane surface charge as studied by deuterium and phosphorus-31 nuclear magnetic resonance. (Marassi FM, Macdonald PM) Biochemistry 1991 Oct 29;30(43):10558-66 PMID: 1931979 SCOPUS ID: 2-s2.0-0026348313 10/29/1991 36 Citations

Response of phosphatidylcholine in the gel and liquid-crystalline states to membrane surface charges. (Macdonald PM, Leisen J, Marassi FM) Biochemistry 1991 Apr 09;30(14):3558-66 PMID: 2012813 SCOPUS ID: 2-s2.0-0025759056 04/09/1991 70 Citations

Surface Acoustic Wave Sensor Response and Molecular Modeling: Selective Binding of Nitrobenzene Derivatives to (Aminopropyl)triethoxysilane (Heckl WM, Marassi FM, Kallury KMR, Stone DC, Thompson M) Analytical Chemistry January 1990;62(1):32-37 SCOPUS ID: 2-s2.0-0025174390 01/01/1990 39 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Francesca M. Marassi PhD

Chair, Professor

Publications (107)