Medical College of Wisconsin
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Hongwei Yu MD

Hongwei Yu MD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Research

Member of the Cardiovascular Center
Member of the Neuroscience Research Center

View Curriculum Vitae

Publications (50)

  • Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain. (Shin SM, Moehring F, Itson-Zoske B, Fan F, Stucky CL, Hogan QH, Yu H) Pain 2021 11 01;162(11):2750-2768 PMID: 34285153 PMCID: PMC8526381 SCOPUS ID: 2-s2.0-85119089549 07/22/2021       1 Citation
  • Recent Insights Into the Protective Mechanisms of Paeoniflorin in Neurological, Cardiovascular, and Renal Diseases. (Jiao F, Varghese K, Wang S, Liu Y, Yu H, Booz GW, Roman RJ, Liu R, Fan F) J Cardiovasc Pharmacol 2021 06 01;77(6):728-734 PMID: 34001724 PMCID: PMC8169546 SCOPUS ID: 2-s2.0-85107318930 05/19/2021       1 Citation
  • Reduced pericyte and tight junction coverage in old diabetic rats are associated with hyperglycemia-induced cerebrovascular pericyte dysfunction. (Liu Y, Zhang H, Wang S, Guo Y, Fang X, Zheng B, Gao W, Yu H, Chen Z, Roman RJ, Fan F) Am J Physiol Heart Circ Physiol 2021 02 01;320(2):H549-H562 PMID: 33306445 PMCID: PMC8082790 SCOPUS ID: 2-s2.0-85100362190 12/12/2020       5 Citations
  • Enhanced T-type calcium channel 3.2 activity in sensory neurons contributes to neuropathic-like pain of monosodium iodoacetate-induced knee osteoarthritis. (Shin SM, Cai Y, Itson-Zoske B, Qiu C, Hao X, Xiang H, Hogan QH, Yu H) Mol Pain 2020 Jan-Dec;16:1744806920963807 PMID: 33054557 PMCID: PMC7570798 SCOPUS ID: 2-s2.0-85092743914 10/16/2020       3 Citations
  • Aging exacerbates impairments of cerebral blood flow autoregulation and cognition in diabetic rats. (Wang S, Lv W, Zhang H, Liu Y, Li L, Jefferson JR, Guo Y, Li M, Gao W, Fang X, Paul IA, Rajkowska G, Shaffery JP, Mosley TH, Hu X, Liu R, Wang Y, Yu H, Roman RJ, Fan F) Geroscience 2020 10;42(5):1387-1410 PMID: 32696219 PMCID: PMC7525432 SCOPUS ID: 2-s2.0-85088304159 07/23/2020       8 Citations
  • Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models. (La Montanara P, Hervera A, Baltussen LL, Hutson TH, Palmisano I, De Virgiliis F, Kong G, Chadwick J, Gao Y, Bartus K, Majid QA, Gorgoraptis N, Wong K, Downs J, Pizzorusso T, Ultanir SK, Leonard H, Yu H, Millar DS, Istvan N, Mazarakis ND, Di Giovanni S) Sci Transl Med 2020 07 08;12(551) PMID: 32641489 PMCID: PMC7116442 SCOPUS ID: 2-s2.0-85087720943 07/10/2020       3 Citations
  • Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain. (Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H) Mol Pain 2020 Jan-Dec;16:1744806920925425 PMID: 32484015 PMCID: PMC7268132 SCOPUS ID: 2-s2.0-85085909943 06/03/2020       5 Citations
  • Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain. (Shin SM, Wang F, Qiu C, Itson-Zoske B, Hogan QH, Yu H) Gene Ther 2020 May 18 PMID: 32424233 PMCID: PMC7671947 SCOPUS ID: 2-s2.0-85085190748 05/20/2020       5 Citations
  • AAV-encoded CaV2.2 peptide aptamer CBD3A6K for primary sensory neuron-targeted treatment of established neuropathic pain. (Yu H, Shin SM, Xiang H, Chao D, Cai Y, Xu H, Khanna R, Pan B, Hogan QH) Gene Ther 2019 08;26(7-8):308-323 PMID: 31118475 PMCID: PMC6707887 SCOPUS ID: 2-s2.0-85066867179 05/24/2019       10 Citations
  • Transmembrane protein 100 is expressed in neurons and glia of dorsal root ganglia and is reduced after painful nerve injury. (Yu H, Shin SM, Wang F, Xu H, Xiang H, Cai Y, Itson-Zoske B, Hogan QH) Pain Rep 2019 Jan-Feb;4(1):e703 PMID: 30801043 PMCID: PMC6370145 SCOPUS ID: 2-s2.0-85061500653 02/26/2019       2 Citations
  • Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno-associated virus delivery in adult rats. (Xiang H, Xu H, Fan F, Shin SM, Hogan QH, Yu H) J Neurosci Res 2018 03;96(3):436-448 PMID: 28941260 PMCID: PMC5766685 SCOPUS ID: 2-s2.0-85030181311 09/25/2017       7 Citations
  • Primary sensory neuron-specific interference of TRPV1 signaling by AAV-encoded TRPV1 peptide aptamer attenuates neuropathic pain. (Xiang H, Liu Z, Wang F, Xu H, Roberts C, Fischer G, Stucky C, Caron D, Pan B, Hogan Q, Yu H) Mol Pain 2017 Jan-Dec;13:1744806917717040 PMID: 28604222 PMCID: PMC5486490 SCOPUS ID: 2-s2.0-85038960017 06/13/2017       10 Citations
  • Inhibition of neuropathic hyperalgesia by intrathecal bone marrow stromal cells is associated with alteration of multiple soluble factors in cerebrospinal fluid. (Fischer G, Wang F, Xiang H, Bai X, Yu H, Hogan QH) Exp Brain Res 2017 09;235(9):2627-2638 PMID: 28573310 PMCID: PMC6688185 SCOPUS ID: 2-s2.0-85020124309 06/03/2017       6 Citations
  • Dorsal Root Ganglionic Field Stimulation Relieves Spontaneous and Induced Neuropathic Pain in Rats. (Pan B, Yu H, Fischer GJ, Kramer JM, Hogan QH) J Pain 2016 12;17(12):1349-1358 PMID: 27687223 SCOPUS ID: 2-s2.0-84997525072 10/01/2016       25 Citations
  • HMG-CoA synthase isoenzymes 1 and 2 localize to satellite glial cells in dorsal root ganglia and are differentially regulated by peripheral nerve injury. (Wang F, Xiang H, Fischer G, Liu Z, Dupont MJ, Hogan QH, Yu H) Brain Res 2016 12 01;1652:62-70 PMID: 27671501 PMCID: PMC5441544 SCOPUS ID: 2-s2.0-84991712739 09/28/2016       15 Citations
  • Peripheral nerve injury induces loss of nociceptive neuron-specific Gαi-interacting protein in neuropathic pain rat. (Liu Z, Wang F, Fischer G, Hogan QH, Yu H) Mol Pain 2016;12 PMID: 27145804 PMCID: PMC4956147 SCOPUS ID: 2-s2.0-85007443266 05/06/2016       12 Citations
  • AAV-Mediated Gene Transfer to Dorsal Root Ganglion. (Yu H, Fischer G, Hogan QH) Methods Mol Biol 2016;1382:251-61 PMID: 26611592 PMCID: PMC5459312 SCOPUS ID: 2-s2.0-84948768833 11/28/2015       10 Citations
  • CaMKII Controls Whether Touch Is Painful. (Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q) J Neurosci 2015 Oct 21;35(42):14086-102 PMID: 26490852 PMCID: PMC4683679 SCOPUS ID: 2-s2.0-84944929761 10/23/2015       17 Citations
  • Differential expression of CaMKII isoforms and overall kinase activity in rat dorsal root ganglia after injury. (Bangaru ML, Meng J, Kaiser DJ, Yu H, Fischer G, Hogan QH, Hudmon A) Neuroscience 2015 Aug 06;300:116-27 PMID: 25982557 PMCID: PMC4485599 SCOPUS ID: 2-s2.0-84930226027 05/20/2015       16 Citations
  • Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results. (Yu H, Fischer G, Ebert AD, Wu HE, Bai X, Hogan QH) Mol Pain 2015 Feb 12;11:5 PMID: 25888914 PMCID: PMC4331376 SCOPUS ID: 2-s2.0-84924280629 04/19/2015       22 Citations
  • Erratum: Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats (PLoS ONE (2013) 8:4 (e61266)) (Yu H, Fischer G, Ferhatovic L, Fan F, Light AR) PLoS ONE 10 February 2015;10(2) SCOPUS ID: 2-s2.0-84922822653 02/10/2015    
  • Painful nerve injury upregulates thrombospondin-4 expression in dorsal root ganglia. (Pan B, Yu H, Park J, Yu YP, Luo ZD, Hogan QH) J Neurosci Res 2015 Mar;93(3):443-53 PMID: 25327416 PMCID: PMC4293337 SCOPUS ID: 2-s2.0-84920911767 10/21/2014       22 Citations
  • Regulation of voltage-gated Ca(2+) currents by Ca(2+)/calmodulin-dependent protein kinase II in resting sensory neurons. (Kostic S, Pan B, Guo Y, Yu H, Sapunar D, Kwok WM, Hudmon A, Wu HE, Hogan QH) Mol Cell Neurosci 2014 Sep;62:10-8 PMID: 25064143 PMCID: PMC4187344 SCOPUS ID: 2-s2.0-84906053798 07/30/2014       8 Citations
  • Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. (Tint GS, Pan L, Shang Q, Sharpe LJ, Brown AJ, Li M, Yu H) Dev Neurosci 2014;36(2):132-42 PMID: 24861183 PMCID: PMC4106903 SCOPUS ID: 2-s2.0-84903599962 05/28/2014       3 Citations
  • Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion. (Fischer G, Pan B, Vilceanu D, Hogan QH, Yu H) Gene Ther 2014 Jan;21(1):44-51 PMID: 24152582 PMCID: PMC3881029 SCOPUS ID: 2-s2.0-84891747283 10/25/2013       32 Citations
  • Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats. (Yu H, Fischer G, Ferhatovic L, Fan F, Light AR, Weihrauch D, Sapunar D, Nakai H, Park F, Hogan QH) PLoS One 2013;8(4):e61266 PMID: 23613824 PMCID: PMC3628918 SCOPUS ID: 2-s2.0-84876189197 04/25/2013       27 Citations
  • Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury. (Tang Q, Bangaru ML, Kostic S, Pan B, Wu HE, Koopmeiners AS, Yu H, Fischer GJ, McCallum JB, Kwok WM, Hudmon A, Hogan QH) J Neurosci 2012 Aug 22;32(34):11737-49 PMID: 22915116 PMCID: PMC3723336 SCOPUS ID: 2-s2.0-84865228570 08/24/2012       25 Citations
  • Lentiviral gene transfer into the dorsal root ganglion of adult rats. (Yu H, Fischer G, Jia G, Reiser J, Park F, Hogan QH) Mol Pain 2011 Aug 23;7:63 PMID: 21861915 PMCID: PMC3179738 SCOPUS ID: 2-s2.0-80052035933 08/25/2011       35 Citations
  • Direct injection into the dorsal root ganglion: technical, behavioral, and histological observations. (Fischer G, Kostic S, Nakai H, Park F, Sapunar D, Yu H, Hogan Q) J Neurosci Methods 2011 Jul 15;199(1):43-55 PMID: 21540055 PMCID: PMC3742008 SCOPUS ID: 2-s2.0-79958117790 05/05/2011       53 Citations
  • Quantifying raft proteins in neonatal mouse brain by 'tube-gel' protein digestion label-free shotgun proteomics. (Yu H, Wakim B, Li M, Halligan B, Tint GS, Patel SB) Proteome Sci 2007 Sep 24;5:17 PMID: 17892558 PMCID: PMC2045652 SCOPUS ID: 2-s2.0-35648988480 09/26/2007       54 Citations
  • Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice. (Yu H, Li M, Tint GS, Chen J, Xu G, Patel SB) BMC Dev Biol 2007 Apr 04;7:27 PMID: 17408495 PMCID: PMC1855921 SCOPUS ID: 2-s2.0-34247533727 04/06/2007       8 Citations
  • Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse. (Solcà C, Pandit B, Yu H, Tint GS, Patel SB) Mol Genet Metab 2007 May;91(1):7-14 PMID: 17197219 PMCID: PMC1852500 SCOPUS ID: 2-s2.0-34047251013 01/02/2007       8 Citations
  • The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. (Tint GS, Yu H, Shang Q, Xu G, Patel SB) J Lipid Res 2006 Jul;47(7):1535-41 PMID: 16651660 PMCID: PMC1488821 SCOPUS ID: 2-s2.0-33746095457 05/03/2006       75 Citations
  • Erratum: Recent insights into the Smith-Lemli-Opitz syndrome (Clinical Genetics (2005) vol. 68 (383-391)) (Yu H, Patel SB) Clinical Genetics December 2005;68(6):570 SCOPUS ID: 2-s2.0-28644452245 12/01/2005    
  • Recent insights into the Smith-Lemli-Opitz syndrome. (Yu H, Patel SB) Clin Genet 2005 Nov;68(5):383-91 PMID: 16207203 PMCID: PMC1350989 SCOPUS ID: 2-s2.0-27544490417 10/07/2005       65 Citations
  • The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension. (Chen J, Batta A, Zheng S, Fitzgibbon WR, Ullian ME, Yu H, Tso P, Salen G, Patel SB) BMC Genet 2005 Jul 18;6:40 PMID: 16026620 PMCID: PMC1190168 SCOPUS ID: 2-s2.0-26444457984 07/20/2005       11 Citations
  • Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression. (Yu H, Wessels A, Tint GS, Patel SB) Brain Res Dev Brain Res 2005 Apr 21;156(1):46-60 PMID: 15862627 SCOPUS ID: 2-s2.0-18044377392 05/03/2005       15 Citations
  • Sitosterolemia; of mice and man (Patel SB, Klett EL, Anh GS, Yu H, Chen J, Pandit B, Lee MH, Salen G) International Congress Series 1 May 2004;1262(C):300-304 SCOPUS ID: 2-s2.0-85023091454 05/01/2004    
  • A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. (Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, Salen G, Patel SB) BMC Med 2004 Mar 24;2:5 PMID: 15040800 PMCID: PMC394351 SCOPUS ID: 2-s2.0-3042601466 03/26/2004       118 Citations
  • Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. (Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB) BMC Dev Biol 2004 Feb 02;4:1 PMID: 15005800 PMCID: PMC341451 SCOPUS ID: 2-s2.0-2642577662 03/10/2004       23 Citations
  • The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats. (Yu H, Pandit B, Klett E, Lee MH, Lu K, Helou K, Ikeda I, Egashira N, Sato M, Klein R, Batta A, Salen G, Patel SB) BMC Cardiovasc Disord 2003 Jun 03;3:4 PMID: 12783625 PMCID: PMC165443 SCOPUS ID: 2-s2.0-0642281260 06/05/2003       32 Citations
  • Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. (Lu K, Lee MH, Yu H, Zhou Y, Sandell SA, Salen G, Patel SB) J Lipid Res 2002 Apr;43(4):565-78 PMID: 11907139 PMCID: PMC1815568 SCOPUS ID: 2-s2.0-0036198630 03/22/2002       55 Citations
  • 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. (Fitzky BU, Moebius FF, Asaoka H, Waage-Baudet H, Xu L, Xu G, Maeda N, Kluckman K, Hiller S, Yu H, Batta AK, Shefer S, Chen T, Salen G, Sulik K, Simoni RD, Ness GC, Glossmann H, Patel SB, Tint GS) J Clin Invest 2001 Sep;108(6):905-15 PMID: 11560960 PMCID: PMC200927 SCOPUS ID: 2-s2.0-0034829757 09/19/2001       132 Citations
  • Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. (Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H, Kojima H, Allikmets R, Sakuma N, Pegoraro R, Srivastava AK, Salen G, Dean M, Patel SB) Nat Genet 2001 Jan;27(1):79-83 PMID: 11138003 PMCID: PMC1350991 SCOPUS ID: 2-s2.0-0035158733 01/04/2001       569 Citations
  • Spectrum of Δ7-dehydrocholesterol reductase mutations in patients with the Smith-Lemli-Opitz (RSH) syndrome (Human Molecular Genetics (2000) vol.9 (1385-1391)) (Yu H, Lee MH, Starch L, Elias ER, Irons M, Salen G, Patel SB, Tint GS) Human Molecular Genetics 2000;9(12):1903 SCOPUS ID: 2-s2.0-0033861699 08/17/2000    
  • Spectrum of Delta(7)-dehydrocholesterol reductase mutations in patients with the Smith-Lemli-Opitz (RSH) syndrome. (Yu H, Lee MH, Starck L, Elias ER, Irons M, Salen G, Patel SB, Tint GS) Hum Mol Genet 2000 May 22;9(9):1385-91 PMID: 10814720 SCOPUS ID: 2-s2.0-0034702085 05/18/2000       85 Citations
  • Detection of a common mutation in the RSH or Smith-Lemli-Opitz syndrome by a PCR-RFLP assay: IVS8-G-->C is found in over sixty percent of US propositi. (Yu H, Tint GS, Salen G, Patel SB) Am J Med Genet 2000 Feb 14;90(4):347-50 PMID: 10710236 SCOPUS ID: 2-s2.0-0033960672 03/10/2000       47 Citations
  • Cyclic AMP-dependent phosphodiesterase isozyme-specific potentiation by protein kinase C in hypertrophic cardiomyopathic hamster hearts. (Yu H, Cai JJ, Lee HC) Mol Pharmacol 1996 Sep;50(3):549-55 PMID: 8794893 SCOPUS ID: 2-s2.0-0029786960 09/01/1996       12 Citations
  • Effect of protein kinase C on cyclic 3',5'-adenosine monophosphate-dependent phosphodiesterase in hypertrophic cardiomyopathic hamster hearts. (Lee HC, Cai JJ, Yu H) J Pharmacol Exp Ther 1994 Sep;270(3):1171-6 PMID: 7932168 SCOPUS ID: 2-s2.0-0028062140 09/01/1994       15 Citations
  • Developmental changes of protein kinase C and Gs alpha in hypertrophic cardiomyopathic hamster hearts. (Cai JJ, Yu H, Lee HC) J Lab Clin Med 1993 Nov;122(5):533-41 PMID: 8228571 SCOPUS ID: 2-s2.0-0027454499 11/01/1993       7 Citations
    • Last update: 11/22/2021