Medical College of Wisconsin
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Matthew Kudek MD

Matthew Kudek MD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Hematology and Oncology - Pediatrics
Program: Oncology

Member of the Cancer Center
Member of the Center for Immunology


I am willing to collaborate on research projects.

View Curriculum Vitae

Research Areas of Interest

  • Adaptive Immunity
  • Graft vs Host Disease
  • Host-Pathogen Interactions
  • Immunity, Innate
  • Immunotherapy, Adoptive
  • Listeria monocytogenes
  • Neoplasms
  • Neuroblastoma
  • T-Lymphocytes
  • immunology

    • Research Experience

  • Bone Marrow Transplantation
  • Cloning, Molecular
  • Flow Cytometry
  • Models, Animal
  • Primary Cell Culture
  • Sequence Analysis, RNA
  • Single-Cell Analysis
  • Transduction, Genetic

    • Clinical Expertise

  • Medical Oncology
  • Pediatrics
  • Precision Medicine

    • Methodologies and Techniques

  • Adoptive Transfer
  • Cell Culture Techniques
  • Cell Transformation, Viral
  • Cloning, Molecular
  • Flow Cytometry
  • Genotyping Techniques
  • Hematopoietic Stem Cell Transplantation
  • Histology
  • Single-Cell Analysis
  • Transcriptome
  • Transplantation, Homologous

    • Publications (14)

  • Ag(e)nostic precision oncology therapy approvals across the years. (Kudek MR, Adashek JJ, Kurzrock R) Trends Cancer 2025 Aug;11(8):726-735 PMID: 40480903 PMCID: PMC12350067 SCOPUS ID: 2-s2.0-105007440053 06/07/2025    
  • Intestinal epithelium-derived IL-34 reprograms macrophages to mitigate gastrointestinal tract graft-versus-host disease. (Rayasam A, Moe A, Kudek M, Shah RK, Yuan CY, Miller JM, Rau M, Patton M, Wanat K, Colonna M, Zamora AE, Drobyski WR) Sci Transl Med 2025 Feb 12;17(785):eadn3963 PMID: 39937882 SCOPUS ID: 2-s2.0-85218479788 02/12/2025       2 Citations
  • Bhlhe40 Promotes CD4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation during Viral Infection. (Nguyen C, Kudek M, Zander R, Niu H, Shen J, Bauer A, Alson D, Khatun A, Chen Y, Sun J, Drobyski W, Edelson BT, Cui W) J Immunol 2024 Jun 01;212(11):1829-1842 PMID: 38619295 PMCID: PMC12359248 SCOPUS ID: 2-s2.0-85194012903 04/15/2024       3 Citations
  • A spatial sequencing atlas of age-induced changes in the lung during influenza infection. (Kasmani MY, Topchyan P, Brown AK, Brown RJ, Wu X, Chen Y, Khatun A, Alson D, Wu Y, Burns R, Lin CW, Kudek MR, Sun J, Cui W) Nat Commun 2023 Oct 18;14(1):6597 PMID: 37852965 PMCID: PMC10584893 SCOPUS ID: 2-s2.0-85174461444 10/19/2023       19 Citations
  • BATF is Required for Treg Homeostasis and Stability to Prevent Autoimmune Pathology. (Khatun A, Wu X, Qi F, Gai K, Kharel A, Kudek MR, Fraser L, Ceicko A, Kasmani MY, Majnik A, Burns R, Chen YG, Salzman N, Taparowsky EJ, Fang D, Williams CB, Cui W) Adv Sci (Weinh) 2023 Oct;10(28):e2206692 PMID: 37587835 PMCID: PMC10558681 SCOPUS ID: 2-s2.0-85168114370 08/17/2023       11 Citations
  • Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer. (Kharel A, Shen J, Brown R, Chen Y, Nguyen C, Alson D, Bluemn T, Fan J, Gai K, Zhang B, Kudek M, Zhu N, Cui W) Cell Rep 2023 Jun 27;42(6):112649 PMID: 37330910 PMCID: PMC10592487 SCOPUS ID: 2-s2.0-85162227177 06/18/2023       15 Citations
  • Lymphocytic Choriomeningitis Virus Clone 13 Infection Results in CD8 T Cell-Mediated Host Mortality in Diacylglycerol Kinase α-Deficient Mice. (Kudek MR, Xin G, Alson D, Holzhauer S, Shen J, Kasmani MY, Riese M, Cui W) J Immunol 2023 May 01;210(9):1281-1291 PMID: 36920384 PMCID: PMC10121876 SCOPUS ID: 2-s2.0-85152632053 03/16/2023    
  • Empowering childhood cancer survivors through integrated, individualized health insurance education (Kimball BC, Kudek MR, van Ly D, Eagle S, Hausman V, Plaunt E, Lee HY, Sadak KT) Precision Cancer Medicine December 2021;4 SCOPUS ID: 2-s2.0-85121643420 12/01/2021    
  • E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. (Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W) Proc Natl Acad Sci U S A 2021 Apr 20;118(16) PMID: 33859041 PMCID: PMC8072256 SCOPUS ID: 2-s2.0-85104381676 04/17/2021       25 Citations
  • Harnessing the IL-21-BATF Pathway in the CD8+ T Cell Anti-Tumor Response. (Topchyan P, Xin G, Chen Y, Zheng S, Burns R, Shen J, Kasmani MY, Kudek M, Yang N, Cui W) Cancers (Basel) 2021 Mar 12;13(6) PMID: 33809259 PMCID: PMC7998696 SCOPUS ID: 2-s2.0-85102393382 04/04/2021       25 Citations
  • Upfront Therapies and Downstream Effects: Navigating Late Effects in Childhood Cancer Survivors in the Current Era. (Phelan R, Eissa H, Becktell K, Bhatt N, Kudek M, Nuechterlein B, Pommert L, Tanaka R, Baker KS) Curr Oncol Rep 2019 Nov 25;21(12):104 PMID: 31768799 SCOPUS ID: 2-s2.0-85075563534 11/27/2019       5 Citations
  • Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Nonmalignant Disease. (Kudek MR, Shanley R, Zantek ND, McKenna DH, Smith AR, Miller WP) Biol Blood Marrow Transplant 2016 Nov;22(11):2019-2024 PMID: 27496217 PMCID: PMC5067229 SCOPUS ID: 2-s2.0-84992437370 08/09/2016       13 Citations
  • Restrictive Diet Control as a Means of Child Abuse. (Kudek MR, Luyet F, Herringa RJ, Knox BL) Pediatr Emerg Care 2018 Mar;34(3):e57-e59 PMID: 26945192 SCOPUS ID: 2-s2.0-84960156253 03/06/2016    
  • Sublingual hematoma: when to suspect child abuse. (Kudek MR, Knox BL) Clin Pediatr (Phila) 2014 Jul;53(8):809-12 PMID: 24707018 SCOPUS ID: 2-s2.0-84902471867 04/08/2014       6 Citations
    • Last update: 10/02/2025