Medical College of Wisconsin
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Abir El-Alfy PhD

Abir El-Alfy PhD profile photo picture

Assistant Dean, Professor

Institution: Medical College of Wisconsin
Department: School of Pharmacy Operations

Publications (25)

  • Chemical diversity and pharmacological significance of the secondary metabolites of nutmeg (Myristica fragrans Houtt.). (Abourashed EA, El-Alfy AT) Phytochem Rev 2016 Dec;15(6):1035-1056 PMID: 28082856 PMCID: PMC5222521 SCOPUS ID: 2-s2.0-84966525966 01/14/2017       127 Citations
  • Indirect modulation of the endocannabinoid system by specific fractions of nutmeg total extract. (El-Alfy AT, Joseph S, Brahmbhatt A, Akati S, Abourashed EA) Pharm Biol 2016 Dec;54(12):2933-2938 PMID: 27296774 SCOPUS ID: 2-s2.0-84974800846 06/15/2016       11 Citations
  • Review of available studies of the neurobiology and pharmacotherapeutic management of trichotillomania. (Johnson J, El-Alfy AT) J Adv Res 2016 Mar;7(2):169-84 PMID: 26966559 PMCID: PMC4767796 SCOPUS ID: 2-s2.0-84959476529 03/12/2016       29 Citations
  • Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa. (Radwan MM, ElSohly MA, El-Alfy AT, Ahmed SA, Slade D, Husni AS, Manly SP, Wilson L, Seale S, Cutler SJ, Ross SA) J Nat Prod 2015 Jun 26;78(6):1271-6 PMID: 26000707 PMCID: PMC4880513 SCOPUS ID: 2-s2.0-84933055128 05/23/2015       112 Citations
  • Anxiolytic action of pterostilbene: involvement of hippocampal ERK phosphorylation. (Al Rahim M, Rimando AM, Silistreli K, El-Alfy AT) Planta Med 2013 Jun;79(9):723-30 PMID: 23677525 SCOPUS ID: 2-s2.0-84879223370 05/17/2013       23 Citations
  • Nature against depression. (El-Alfy AT, Abourashed EA, Matsumoto RR) Curr Med Chem 2012;19(14):2229-41 PMID: 22414105 SCOPUS ID: 2-s2.0-84860661296 03/15/2012       19 Citations
  • Neurobehavioral and transcriptional effects of acrylamide in juvenile rats. (Seale SM, Feng Q, Agarwal AK, El-Alfy AT) Pharmacol Biochem Behav 2012 Mar;101(1):77-84 PMID: 22197712 SCOPUS ID: 2-s2.0-84855805905 12/27/2011       49 Citations
  • Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (El-Alfy AT, Ivey K, Robinson K, Ahmed S, Radwan M, Slade D, Khan I, ElSohly M, Ross S) Pharmacol Biochem Behav 2010 Jun;95(4):434-42 PMID: 20332000 PMCID: PMC2866040 SCOPUS ID: 2-s2.0-77952551436 03/25/2010       251 Citations
  • Towards a better understanding of the psychopharmacology of nutmeg: Activities in the mouse tetrad assay. (El-Alfy AT, Wilson L, ElSohly MA, Abourashed EA) J Ethnopharmacol 2009 Nov 12;126(2):280-6 PMID: 19703539 PMCID: PMC2783227 SCOPUS ID: 2-s2.0-70350346860 08/26/2009       32 Citations
  • Naturally occurring and related synthetic cannabinoids and their potential therapeutic applications. (Galal AM, Slade D, Gul W, El-Alfy AT, Ferreira D, Elsohly MA) Recent Pat CNS Drug Discov 2009 Jun;4(2):112-36 PMID: 19519560 SCOPUS ID: 2-s2.0-68849093152 06/13/2009       41 Citations
  • Non-cannabinoid constituents from a high potency Cannabis sativa variety. (Radwan MM, Elsohly MA, Slade D, Ahmed SA, Wilson L, El-Alfy AT, Khan IA, Ross SA) Phytochemistry 2008 Oct;69(14):2627-33 PMID: 18774146 PMCID: PMC4888767 SCOPUS ID: 2-s2.0-56949101880 09/09/2008       120 Citations
  • Secondary metabolites from three Florida sponges with antidepressant activity. (Kochanowska AJ, Rao KV, Childress S, El-Alfy A, Matsumoto RR, Kelly M, Stewart GS, Sufka KJ, Hamann MT) J Nat Prod 2008 Feb;71(2):186-9 PMID: 18217716 PMCID: PMC4918908 SCOPUS ID: 2-s2.0-40549109549 01/26/2008       73 Citations
  • Amelioration of the cardiovascular manifestations of the yellow scorpion Leiurus quinquestriatus envenomation in rats by red grape seeds proanthocyanidins. (El-Alfy AT, Ahmed AA, Fatani AJ, Kader F) Toxicon 2008 Mar 01;51(3):321-33 PMID: 18191975 SCOPUS ID: 2-s2.0-39149104020 01/15/2008       16 Citations
  • Identification of antidepressant drug leads through the evaluation of marine natural products with neuropsychiatric pharmacophores. (Diers JA, Ivey KD, El-Alfy A, Shaikh J, Wang J, Kochanowska AJ, Stoker JF, Hamann MT, Matsumoto RR) Pharmacol Biochem Behav 2008 Mar;89(1):46-53 PMID: 18037479 PMCID: PMC4480916 SCOPUS ID: 2-s2.0-38049153250 11/27/2007       29 Citations
  • Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats. (El-Alfy AT, Ahmed AA, Fatani AJ) Pharmacol Res 2005 Sep;52(3):264-70 PMID: 15925517 SCOPUS ID: 2-s2.0-22144469767 06/01/2005       168 Citations
  • Synthesis and pharmacological screening for muscle relaxant, anticonvulsant, and sedative activities of certain organic compounds produced by Michael addition. (Said MM, Ahmed AA, El-Alfy AT) Arch Pharm Res 2004 Dec;27(12):1194-201 PMID: 15646790 SCOPUS ID: 2-s2.0-13744256326 01/14/2005       6 Citations
  • Ephedra in perspective--a current review. (Abourashed EA, El-Alfy AT, Khan IA, Walker L) Phytother Res 2003 Aug;17(7):703-12 PMID: 12916063 SCOPUS ID: 2-s2.0-0041976090 08/14/2003       233 Citations
  • Effect of cortisol and urea on flavin monooxygenase activity and expression in rainbow trout, Oncorhynchus mykiss. (El-Alfy A, Larsen B, Schlenk D) Mar Environ Res 2002;54(3-5):275-8 PMID: 12408576 SCOPUS ID: 2-s2.0-0036753537 11/01/2002       13 Citations
  • Gender differences in the effect of salinity on aldicarb uptake, elimination, and in vitro metabolism in Japanese medaka, Oryzias latipes. (El-Alfy AT, Bernache E, Schlenk D) Aquat Toxicol 2002 Dec 03;61(3-4):225-32 PMID: 12359392 SCOPUS ID: 2-s2.0-0037015946 10/03/2002       9 Citations
  • Effect of 17beta-estradiol and testosterone on the expression of flavin-containing monooxygenase and the toxicity of aldicarb to Japanese medaka, Oryzias latipes. (El-Alfy AT, Schlenk D) Toxicol Sci 2002 Aug;68(2):381-8 PMID: 12151634 SCOPUS ID: 2-s2.0-0036667380 08/02/2002       40 Citations
  • Characterization of salinity-enhanced toxicity of aldicarb to Japanese medaka: sexual and developmental differences. (El-Alfy AT, Grisle S, Schlenk D) Environ Toxicol Chem 2001 Sep;20(9):2093-8 PMID: 11521840 SCOPUS ID: 2-s2.0-0034887414 08/28/2001       41 Citations
  • Effects of the oxidant potassium permanganate on the expression of gill metallothionein mRNA and its relationship to sublethal whole animal endpoints in channel catfish. (Schlenk D, Colley WC, El-Alfy A, Kirby R, Griffin BR) Toxicol Sci 2000 Mar;54(1):177-82 PMID: 10746944 SCOPUS ID: 2-s2.0-0034065940 04/04/2000       19 Citations
  • In vitro sulfoxidation of aldicarb by hepatic microsomes of channel catfish, Ictalurus punctatus. (Perkins EJ, el-Alfy A, Schlenk D) Toxicol Sci 1999 Mar;48(1):67-73 PMID: 10330685 SCOPUS ID: 2-s2.0-0033017209 05/20/1999       27 Citations
  • Potential mechanisms of the enhancement of aldicarb toxicity to Japanese medaka, Oryzias latipes, at high salinity. (El-Alfy A, Schlenk D) Toxicol Appl Pharmacol 1998 Sep;152(1):175-83 PMID: 9772213 SCOPUS ID: 2-s2.0-0031769590 10/17/1998       36 Citations
  • Down regulation of hepatic flavin-containing monooxygenase activity by 17 beta-estradiol in rainbow trout (Oncorhynchus mykiss). (Schlenk D, El-Alfy A, Buhler DR) Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1997 Oct;118(2):199-202 PMID: 9490186 SCOPUS ID: 2-s2.0-0031469074 01/24/1998       9 Citations
    • Last update: 10/08/2025