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Christina Runge PhD

Christina Runge PhD

Associate Provost, Chief, Professor

Institution: Medical College of Wisconsin
Department: Otolaryngology
Program: Clinical

Member of the Cancer Center
Member of the Neuroscience Research Center
Member of the Genomic Sciences and Precision Medicine Center (GSPMC)


Research Experience

  • Allied Health Occupations
  • Anatomy Category
  • Audiology
  • Biological Science Disciplines
  • Biomedical Engineering
  • Biophysics
  • Cardiovascular Diseases
  • Cochlear Microphonic Potentials
  • Congenital Abnormalities
  • Congenital, Hereditary, and Neonatal Diseases and Abnormalities
  • Disciplines and Occupations Category
  • Diseases Category
  • Ear
  • Ear Diseases
  • Electrophysiology
  • Engineering
  • Event-Related Potentials, P300
  • Evoked Potentials
  • Evoked Potentials, Auditory
  • Evoked Potentials, Auditory, Brain Stem
  • Genetic Diseases, Inborn
  • Genetic Predisposition to Disease
  • Genotype
  • Health Care Category
  • Health Occupations
  • Health Services Administration
  • Heterozygote
  • Homozygote
  • Infant, Newborn, Diseases
  • Nervous System Diseases
  • Neurophysiology
  • Neurosciences
  • Organization and Administration
  • Otorhinolaryngologic Diseases
  • Phenomena and Processes Category
  • Phenotype
  • Physics
  • Physiological Phenomena
  • Physiology
  • Program Development
  • Quality of Health Care
  • Sense Organs
  • Clinical Expertise

  • Biological Science Disciplines
  • Biophysics
  • Cochlear Microphonic Potentials
  • Deafness
  • Disciplines and Occupations Category
  • Diseases Category
  • Ear Diseases
  • Electrophysiology
  • Event-Related Potentials, P300
  • Evoked Potentials
  • Evoked Potentials, Auditory
  • Evoked Potentials, Auditory, Brain Stem
  • Hearing Disorders
  • Hearing Loss
  • Hearing Loss, Bilateral
  • Hearing Loss, Conductive
  • Hearing Loss, Functional
  • Hearing Loss, High-Frequency
  • Hearing Loss, Mixed Conductive-Sensorineural
  • Hearing Loss, Sensorineural
  • Hearing Loss, Unilateral
  • Natural Science Disciplines
  • Neurophysiology
  • Neurosciences
  • Otorhinolaryngologic Diseases
  • Phenomena and Processes Category
  • Physics
  • Physiological Phenomena
  • Physiology
  • Leadership Positions

  • Associate Professor, Department of Otolaryngology and Communication Sciences
  • Director, Koss Cochlear Implant Program
  • Chief, Division of Communication Sciences
  • Director of Faculty Development
  • Community Partnerships

  • Board of Directors, Center for Communication, Hearing, and Deafness
  • Publications

  • Audiological and clinical outcomes of a transcutaneous bone conduction hearing implant: Six-month results from a multicentre study. (den Besten CA, Monksfield P, Bosman A, Skarzynski PH, Green K, Runge C, Wigren S, Blechert JI, Flynn MC, Mylanus EAM, Hol MKS) Clin Otolaryngol 2018 Oct 25 PMID: 30358920 10/26/2018    
  • TMTC2 variant associated with sensorineural hearing loss and auditory neuropathy spectrum disorder in a family dyad. (Guillen-Ahlers H, Erbe CB, Chevalier FD, Montoya MJ, Zimmerman KD, Langefeld CD, Olivier M, Runge CL) Mol Genet Genomic Med 2018 Apr 19 PMID: 29671961 PMCID: PMC6081214 04/20/2018    
  • TMTC2 variant associated with sensorineural hearing loss and auditory neuropathy spectrum disorder in a family dyad (Guillen-Ahlers H, Erbe CB, Chevalier FD, Montoya MJ, Zimmerman KD, Langefeld CD, Olivier M, Runge CL) Molecular Genetics and Genomic Medicine (in press) 04/19/2018    
  • Improved Speech Perception in Cochlear Implant Users With Interleaved High-Rate Pulse Trains. (Runge CL, Du F, Hu Y) Otol Neurotol 2018 Jun;39(5):e319-e324 PMID: 29649048 04/13/2018    
  • Tablet-based Screening for Hearing Loss: Feasibility of Testing in Nonspecialty Locations. (Kelly EA, Stadler ME, Nelson S, Runge CL, Friedland DR) Otol Neurotol 2018 Apr;39(4):410-416 PMID: 29494473 03/02/2018    
  • Multicenter US Clinical Trial With an Electric-Acoustic Stimulation (EAS) System in Adults: Final Outcomes. (Pillsbury HC 3rd, Dillon MT, Buchman CA, Staecker H, Prentiss SM, Ruckenstein MJ, Bigelow DC, Telischi FF, Martinez DM, Runge CL, Friedland DR, Blevins NH, Larky JB, Alexiades G, Kaylie DM, Roland PS, Miyamoto RT, Backous DD, Warren FM, El-Kashlan HK, Slager HK, Reyes C, Racey AI, Adunka OF) Otol Neurotol 2018 Mar;39(3):299-305 PMID: 29342054 PMCID: PMC5821485 01/18/2018    
  • Temporal and spectral contributions to musical instrument identification and discrimination among cochlear implant users. (Prentiss SM, Friedland DR, Fullmer T, Crane A, Stoddard T, Runge CL) World J Otorhinolaryngol Head Neck Surg 2016 Sep;2(3):148-156 PMID: 29204560 PMCID: PMC5698532 12/06/2017    
  • Temporal and Spectral Contributions to Musical Instrument Identification and Discrimination Among Cochlear Implant Users (Prentiss SM, Friedland DR, Fullmer T, Crane A, Stoddard T, Runge CL) World Journal of Otorhinolaryngology-Head and Neck Surgery September 2016 Vol2(3) pp. 148-156 12/16/2016    
  • Clinical Outcomes of the Cochlear™ Nucleus(®) 5 Cochlear Implant System and SmartSound™ 2 Signal Processing. (Runge CL, Henion K, Tarima S, Beiter A, Zwolan TA) J Am Acad Audiol 2016 06;27(6):425-40 PMID: 27310402 06/17/2016       3 Citations
  • Association of TMTC2 With Human Nonsyndromic Sensorineural Hearing Loss. (Runge CL, Indap A, Zhou Y, Kent JW Jr, King E, Erbe CB, Cole R, Littrell J, Merath K, James R, Rüschendorf F, Kerschner JE, Marth G, Hübner N, Göring HH, Friedland DR, Kwok WM, Olivier M) JAMA Otolaryngol Head Neck Surg 2016 09 01;142(9):866-72 PMID: 27311106 PMCID: PMC5025373 06/17/2016       4 Citations
  • Evaluation of a spectral subtraction strategy to suppress reverberant energy in cochlear implant devices. (Kokkinakis K, Runge C, Tahmina Q, Hu Y) J Acoust Soc Am 2015 Jul;138(1):115-24 PMID: 26233012 PMCID: PMC5392068 08/04/2015       2 Citations
  • Differences in Perception of Musical Stimuli among Acoustic, Electric, and Combined Modality Listeners. (Prentiss SM, Friedland DR, Nash JJ, Runge CL) J Am Acad Audiol 2015 May;26(5):494-501 PMID: 26055838 06/10/2015       2 Citations
  • The role of age on cochlear implant performance, use, and health utility: a multicenter clinical trial. (Zwolan TA, Henion K, Segel P, Runge C) Otol Neurotol 2014 Oct;35(9):1560-8 PMID: 25203562 09/10/2014       6 Citations
  • Patient Outcomes in Magnet-Based Implantable Auditory Assist Devices. (O'Niel MB, Runge CL, Friedland DR, Kerschner JE) JAMA Otolaryngol Head Neck Surg 2014 Jun;140(6):513-20 PMID: 24763485 04/26/2014       19 Citations
  • The perception of telephone-processed speech by combined electric and acoustic stimulation. (Hu Y, Tahmina Q, Runge C, Friedland DR) Trends Amplif 2013 Sep-Dec;17(3):189-96 PMID: 24265213 PMCID: PMC4070615 11/23/2013    
  • A novel otoferlin splice-site mutation in siblings with auditory neuropathy spectrum disorder. (Runge CL, Erbe CB, McNally MT, Van Dusen C, Friedland DR, Kwitek AE, Kerschner JE) Audiol Neurootol 2013;18(6):374-82 PMID: 24135434 PMCID: PMC3877672 10/19/2013       5 Citations
  • Variant discovery in targeted resequencing using whole genome amplified DNA. (Indap AR, Cole R, Runge CL, Marth GT, Olivier M) BMC Genomics 2013 Jul 10;14:468 PMID: 23837845 PMCID: PMC3716764 07/11/2013       5 Citations
  • Statistical model for prediction of hearing loss in patients receiving cisplatin chemotherapy. (Johnson A, Tarima S, Wong S, Friedland DR, Runge CL) JAMA Otolaryngol Head Neck Surg 2013 Mar;139(3):256-64 PMID: 23429908 02/23/2013       1 Citations
  • Effects of Stimulation Rate on Musical Instrument Identification. (Zhang H, Runge C, Friedland DR) Otolaryngol Head Neck Surg 2012 Aug;147(2 suppl):P207 PMID: 25718735 08/01/2012    
  • Bimodal Hearing on Music and Speech with FSP and HDCIS. (Atwood K, Runge C, Friedland DR) Otolaryngol Head Neck Surg 2012 Aug;147(2 suppl):P81 PMID: 25719115 08/01/2012    
  • Recovery from forward masking in elderly cochlear implant users. (Lee ER, Friedland DR, Runge CL) Otol Neurotol 2012 Apr;33(3):355-63 PMID: 22410729 03/14/2012       13 Citations
  • Electrode failure and device failure in adult cochlear implantation. (Schow B, Friedland DR, Jensen J, Burg L, Runge CL) Cochlear Implants Int 2012 Feb;13(1):35-40 PMID: 22340750 02/22/2012       6 Citations
  • Aiding and occluding the contralateral ear in implanted children with auditory neuropathy spectrum disorder. (Runge CL, Jensen J, Friedland DR, Litovsky RY, Tarima S) J Am Acad Audiol 2011 Oct;22(9):567-77 PMID: 22192602 PMCID: PMC3404494 12/24/2011       8 Citations
  • Hearing preservation surgery: proposal for an evidence-based grading scale. (Friedland DR, Runge C) Cochlear Implants Int 2011 May;12 Suppl 1:S76-7 PMID: 21756480 08/04/2011       1 Citations
  • Rate of neural recovery in implanted children with auditory neuropathy spectrum disorder. (Fulmer SL, Runge CL, Jensen JW, Friedland DR) Otolaryngol Head Neck Surg 2011 Feb;144(2):274-9 PMID: 21493430 04/16/2011       15 Citations
  • Case-control analysis of cochlear implant performance in elderly patients. (Friedland DR, Runge-Samuelson C, Baig H, Jensen J) Arch Otolaryngol Head Neck Surg 2010 May;136(5):432-8 PMID: 20479370 05/19/2010       47 Citations
  • The rocky road toward clinical genetic testing: insights into the physio-genetic basis of hearing loss. (Runge-Samuelson C, Olivier M) Physiol Genomics 2009 Oct 07;39(2):83-4 PMID: 19706690 PMCID: PMC2765068 08/27/2009       2 Citations
  • Soft cochlear implantation: rationale for the surgical approach. (Friedland DR, Runge-Samuelson C) Trends Amplif 2009 Jun;13(2):124-38 PMID: 19447766 PMCID: PMC4111526 05/19/2009       52 Citations
  • Effects of high-rate pulse trains on electrode discrimination in cochlear implant users. (Runge-Samuelson CL) Trends Amplif 2009 Jun;13(2):76-86 PMID: 19447763 PMCID: PMC2763511 05/19/2009       2 Citations
  • Electrically evoked auditory brainstem responses in adults and children: effects of lateral to medial placement of the nucleus 24 contour electrode array. (Runge-Samuelson C, Firszt JB, Gaggl W, Wackym PA) Otol Neurotol 2009 Jun;30(4):464-70 PMID: 19300297 03/21/2009       6 Citations
  • Gamma Knife surgery of vestibular schwannomas: longitudinal changes in vestibular function and measurement of the Dizziness Handicap Inventory. (Wackym PA, Hannley MT, Runge-Samuelson CL, Jensen J, Zhu YR) J Neurosurg 2008 Dec;109 Suppl:137-43 PMID: 19123900 01/10/2009       17 Citations
  • Feasibility of auditory cortical stimulation for the treatment of tinnitus. (Friedland DR, Gaggl W, Runge-Samuelson C, Ulmer JL, Kopell BH) Otol Neurotol 2007 Dec;28(8):1005-12 PMID: 18043428 11/29/2007       55 Citations
  • Quantitative analysis of electrically evoked auditory brainstem responses in implanted children with auditory neuropathy/dyssynchrony. (Runge-Samuelson CL, Drake S, Wackym PA) Otol Neurotol 2008 Feb;29(2):174-8 PMID: 18025997 11/21/2007       16 Citations
  • More challenging speech-perception tasks demonstrate binaural benefit in bilateral cochlear implant users. (Wackym PA, Runge-Samuelson CL, Firszt JB, Alkaf FM, Burg LS) Ear Hear 2007 Apr;28(2 Suppl):80S-85S PMID: 17496654 05/15/2007       39 Citations
  • Biomechanical strength of reconstruction plates when used for medial support of MED-El cochlear implants: implications for diagnostic MRI. (Poetker DM, Wackym PA, Yoganandan N, Runge-Samuelson CL, Firszt JB, Pintar FA) ORL J Otorhinolaryngol Relat Spec 2006;68(2):77-82 PMID: 16432305 01/25/2006       5 Citations
  • Distortion of magnetic resonance images used in gamma knife radiosurgery treatment planning: implications for acoustic neuroma outcomes. (Poetker DM, Jursinic PA, Runge-Samuelson CL, Wackym PA) Otol Neurotol 2005 Nov;26(6):1220-8 PMID: 16272946 11/08/2005       13 Citations
  • Electrosurgery after cochlear implantation: eighth nerve electrophysiology. (Poetker DM, Runge-Samuelson CL, Firszt JB, Wackym PA) Laryngoscope 2004 Dec;114(12):2252-4 PMID: 15564856 11/27/2004       11 Citations
  • Gamma knife radiosurgery for acoustic neuromas performed by a neurotologist: early experiences and outcomes. (Wackym PA, Runge-Samuelson CL, Poetker DM, Michel MA, Alkaf FM, Burg LS, Firszt JB) Otol Neurotol 2004 Sep;25(5):752-61 PMID: 15354007 09/09/2004       27 Citations
  • Fungal biofilm formation on cochlear implant hardware after antibiotic-induced fungal overgrowth within the middle ear. (Cristobal R, Edmiston CE Jr, Runge-Samuelson CL, Owen HA, Firszt JB, Wackym PA) Pediatr Infect Dis J 2004 Aug;23(8):774-8 PMID: 15295230 08/06/2004       17 Citations
  • Recognition of speech presented at soft to loud levels by adult cochlear implant recipients of three cochlear implant systems. (Firszt JB, Holden LK, Skinner MW, Tobey EA, Peterson A, Gaggl W, Runge-Samuelson CL, Wackym PA) Ear Hear 2004 Aug;25(4):375-87 PMID: 15292777 08/05/2004       136 Citations
  • Effect of magnetic resonance imaging on internal magnet strength in Med-El Combi 40+ cochlear implants. (Wackym PA, Michel MA, Prost RW, Banks KL, Runge-Samuelson CL, Firszt JB) Laryngoscope 2004 Aug;114(8):1355-61 PMID: 15280707 07/29/2004       31 Citations
  • Response of the auditory nerve to sinusoidal electrical stimulation: effects of high-rate pulse trains. (Runge-Samuelson CL, Abbas PJ, Rubinstein JT, Miller CA, Robinson BK) Hear Res 2004 Aug;194(1-2):1-13 PMID: 15276671 07/28/2004       12 Citations
  • Auditory sensitivity in children using the auditory steady-state response. (Firszt JB, Gaggl W, Runge-Samuelson CL, Burg LS, Wackym PA) Arch Otolaryngol Head Neck Surg 2004 May;130(5):536-40 PMID: 15148173 05/19/2004       31 Citations
  • Connexin 26 and connexin 30 mutations in children with nonsyndromic hearing loss. (Erbe CB, Harris KC, Runge-Samuelson CL, Flanary VA, Wackym PA) Laryngoscope 2004 Apr;114(4):607-11 PMID: 15064611 04/06/2004       23 Citations
  • Electrophysiologic effects of placing cochlear implant electrodes in a perimodiolar position in young children. (Wackym PA, Firszt JB, Gaggl W, Runge-Samuelson CL, Reeder RM, Raulie JC) Laryngoscope 2004 Jan;114(1):71-6 PMID: 14709998 01/08/2004       31 Citations
  • Auditory nerve responses to monophasic and biphasic electric stimuli. (Miller CA, Robinson BK, Rubinstein JT, Abbas PJ, Runge-Samuelson CL) Hear Res 2001 Jan;151(1-2):79-94 PMID: 11124454 12/22/2000       54 Citations
  • Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13). (McGuirt WT, Prasad SD, Griffith AJ, Kunst HP, Green GE, Shpargel KB, Runge C, Huybrechts C, Mueller RF, Lynch E, King MC, Brunner HG, Cremers CW, Takanosu M, Li SW, Arita M, Mayne R, Prockop DJ, Van Camp G, Smith RJ) Nat Genet 1999 Dec;23(4):413-9 PMID: 10581026 12/02/1999       172 Citations
  • Last update: 01/02/2019
    jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6