Medical College of Wisconsin
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Daisy Sahoo PhD

Daisy Sahoo PhD

Vice Chairman, Associate Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Research

Member of the Cardiovascular Center

View Curriculum Vitae

Publications

  • Tryptophan 415 Is Critical for the Cholesterol Transport Functions of Scavenger Receptor BI. (Holme RL, Miller JJ, Nicholson K, Sahoo D) Biochemistry 2016 Jan 12;55(1):103-13 PMID: 26652912 12/15/2015
  • Oxidized LDL-bound CD36 recruits an Na⁺/K⁺-ATPase-Lyn complex in macrophages that promotes atherosclerosis. (Chen Y, Kennedy DJ, Ramakrishnan DP, Yang M, Huang W, Li Z, Xie Z, Chadwick AC, Sahoo D, Silverstein RL) Sci Signal 2015 Sep 8;8(393):ra91 PMID: 26350901 PMCID: PMC4852751 09/10/2015
  • Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress. (Korytowski W, Wawak K, Pabisz P, Schmitt JC, Chadwick AC, Sahoo D, Girotti AW) Arterioscler Thromb Vasc Biol 2015 Oct;35(10):2104-13 PMID: 26315403 PMCID: PMC4601804 09/01/2015
  • Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake. (Pollard RD, Blesso CN, Zabalawi M, Fulp B, Gerelus M, Zhu X, Lyons EW, Nuradin N, Francone OL, Li XA, Sahoo D, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2015 Jun 19;290(25):15496-511 PMID: 25947382 PMCID: PMC4505464 05/08/2015
  • Acrolein impairs the cholesterol transport functions of high density lipoproteins. (Chadwick AC, Holme RL, Chen Y, Thomas MJ, Sorci-Thomas MG, Silverstein RL, Pritchard KA Jr, Sahoo D) PLoS One 2015;10(4):e0123138 PMID: 25849485 PMCID: PMC4388475 04/08/2015
  • Inhibition of an NAD⁺ salvage pathway provides efficient and selective toxicity to human pluripotent stem cells. (Kropp EM, Oleson BJ, Broniowska KA, Bhattacharya S, Chadwick AC, Diers AR, Hu Q, Sahoo D, Hogg N, Boheler KR, Corbett JA, Gundry RL) Stem Cells Transl Med 2015 May;4(5):483-93 PMID: 25834119 PMCID: PMC4414215 04/03/2015
  • Identification and specification of the mouse skeletal stem cell. (Chan CK, Seo EY, Chen JY, Lo D, McArdle A, Sinha R, Tevlin R, Seita J, Vincent-Tompkins J, Wearda T, Lu WJ, Senarath-Yapa K, Chung MT, Marecic O, Tran M, Yan KS, Upton R, Walmsley GG, Lee AS, Sahoo D, Kuo CJ, Weissman IL, Longaker MT) Cell 2015 Jan 15;160(1-2):285-98 PMID: 25594184 PMCID: PMC4297645 01/17/2015
  • Expression, purification and reconstitution of the C-terminal transmembrane domain of scavenger receptor BI into detergent micelles for NMR analysis. (Chadwick AC, Jensen DR, Peterson FC, Volkman BF, Sahoo D) Protein Expr Purif 2015 Mar;107:35-42 PMID: 25461971 PMCID: PMC4270826 12/03/2014
  • SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport. (Kartz GA, Holme RL, Nicholson K, Sahoo D) Biochemistry 2014 Oct 7;53(39):6173-82 PMID: 25211142 PMCID: PMC4188264 09/12/2014
  • Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks. (Chadwick AC, Sahoo D) Curr Opin Endocrinol Diabetes Obes 2013 Apr;20(2):124-31 PMID: 23403740 PMCID: PMC3967407 02/14/2013
  • Functional characterization of newly-discovered mutations in human SR-BI. (Chadwick AC, Sahoo D) PLoS One 2012;7(9):e45660 PMID: 23029167 PMCID: PMC3448639 10/03/2012
  • Cholesterol and lipoprotein dynamics in a hibernating mammal. (Otis JP, Sahoo D, Drover VA, Yen CL, Carey HV) PLoS One 2011;6(12):e29111 PMID: 22195001 PMCID: PMC3240636 12/24/2011
  • Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport. (Papale GA, Hanson PJ, Sahoo D) Biochemistry 2011 Jul 19;50(28):6245-54 PMID: 21675794 PMCID: PMC3940413 06/17/2011
  • Extracellular hydrophobic regions in scavenger receptor BI play a key role in mediating HDL-cholesterol transport. (Papale GA, Nicholson K, Hanson PJ, Pavlovic M, Drover VA, Sahoo D) Arch Biochem Biophys 2010 Apr 15;496(2):132-9 PMID: 20219439 PMCID: PMC2853188 03/12/2010
  • CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. (Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC) J Biol Chem 2008 May 9;283(19):13108-15 PMID: 18332148 PMCID: PMC2442355 03/12/2008
  • Scavenger receptor class B, type I (SR-BI) homo-dimerizes via its C-terminal region: fluorescence resonance energy transfer analysis. (Sahoo D, Peng Y, Smith JR, Darlington YF, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):818-29 PMID: 17556017 PMCID: PMC1993887 06/09/2007
  • Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers. (Sahoo D, Darlington YF, Pop D, Williams DL, Connelly MA) Biochim Biophys Acta 2007 Jul;1771(7):807-17 PMID: 16624615 04/21/2006
  • CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. (Drover VA, Ajmal M, Nassir F, Davidson NO, Nauli AM, Sahoo D, Tso P, Abumrad NA) J Clin Invest 2005 May;115(5):1290-7 PMID: 15841205 PMCID: PMC1074677 04/21/2005
  • Glycine 420 near the C-terminal transmembrane domain of SR-BI is critical for proper delivery and metabolism of high density lipoprotein cholesteryl ester. (Parathath S, Sahoo D, Darlington YF, Peng Y, Collins HL, Rothblat GH, Williams DL, Connelly MA) J Biol Chem 2004 Jun 11;279(24):24976-85 PMID: 15060063 04/03/2004
  • ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes. (Sahoo D, Trischuk TC, Chan T, Drover VA, Ho S, Chimini G, Agellon LB, Agnihotri R, Francis GA, Lehner R) J Lipid Res 2004 Jun;45(6):1122-31 PMID: 14993246 03/03/2004
  • Apolipoprotein A-II regulates HDL stability and affects hepatic lipase association and activity. (Boucher J, Ramsamy TA, Braschi S, Sahoo D, Neville TA, Sparks DL) J Lipid Res 2004 May;45(5):849-58 PMID: 14967812 02/18/2004
  • Lipid-triggered conformational switch of apolipophorin III helix bundle to an extended helix organization. (Sahoo D, Weers PM, Ryan RO, Narayanaswami V) J Mol Biol 2002 Aug 9;321(2):201-14 PMID: 12144779 07/30/2002
  • Pyrene excimer fluorescence: a spatially sensitive probe to monitor lipid-induced helical rearrangement of apolipophorin III. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) Biochemistry 2000 Jun 6;39(22):6594-601 PMID: 10828977 06/01/2000
  • NMR evidence for a conformational adaptation of apolipophorin III upon lipid association. (Wang J, Sahoo D, Sykes BD, Ryan RO) Biochem Cell Biol 1998;76(2-3):276-83 PMID: 9923696 01/29/1999
  • Fluorescence studies of exchangeable apolipoprotein-lipid interactions. Superficial association of apolipophorin III with lipoprotein surfaces. (Sahoo D, Narayanaswami V, Kay CM, Ryan RO) J Biol Chem 1998 Jan 16;273(3):1403-8 PMID: 9430675 01/27/1998
    • Last update: 09/26/2016