Medical College of Wisconsin
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Hongwei Yu MD

Associate Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Research

Member of the Cardiovascular Center


  • Dorsal Root Ganglionic Field Stimulation Relieves Spontaneous and Induced Neuropathic Pain in Rats. (Pan B, Yu H, Fischer GJ, Kramer JM, Hogan QH) J Pain 2016 12;17(12):1349-1358 PMID: 27687223 10/01/2016       10 Citations
  • HMG-CoA synthase isoenzymes 1 and 2 localize to satellite glial cells in dorsal root ganglia and are differentially regulated by peripheral nerve injury. (Wang F, Xiang H, Fischer G, Liu Z, Dupont MJ, Hogan QH, Yu H) Brain Res 2016 12 01;1652:62-70 PMID: 27671501 PMCID: PMC5441544 09/28/2016       3 Citations
  • Peripheral nerve injury induces loss of nociceptive neuron-specific Gαi-interacting protein in neuropathic pain rat. (Liu Z, Wang F, Fischer G, Hogan QH, Yu H) Mol Pain 2016;12 PMID: 27145804 PMCID: PMC4956147 05/06/2016       2 Citations
  • AAV-Mediated Gene Transfer to Dorsal Root Ganglion. (Yu H, Fischer G, Hogan QH) Methods Mol Biol 2016;1382:251-61 PMID: 26611592 PMCID: PMC5459312 11/28/2015       5 Citations
  • CaMKII Controls Whether Touch Is Painful. (Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q) J Neurosci 2015 Oct 21;35(42):14086-102 PMID: 26490852 PMCID: PMC4683679 10/23/2015       7 Citations
  • Regulation of voltage-gated Ca(2+) currents by Ca(2+)/calmodulin-dependent protein kinase II in resting sensory neurons. (Kostic S, Pan B, Guo Y, Yu H, Sapunar D, Kwok WM, Hudmon A, Wu HE, Hogan QH) Mol Cell Neurosci 2014 Sep;62:10-8 PMID: 25064143 PMCID: PMC4187344 07/30/2014       5 Citations
  • Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. (Tint GS, Pan L, Shang Q, Sharpe LJ, Brown AJ, Li M, Yu H) Dev Neurosci 2014;36(2):132-42 PMID: 24861183 PMCID: PMC4106903 05/28/2014    
  • Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion. (Fischer G, Pan B, Vilceanu D, Hogan QH, Yu H) Gene Ther 2014 Jan;21(1):44-51 PMID: 24152582 PMCID: PMC3881029 10/25/2013       22 Citations
  • Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats. (Yu H, Fischer G, Ferhatovic L, Fan F, Light AR, Weihrauch D, Sapunar D, Nakai H, Park F, Hogan QH) PLoS One 2013;8(4):e61266 PMID: 23613824 PMCID: PMC3628918 04/25/2013       17 Citations
  • Ca²⁺-dependent regulation of Ca²⁺ currents in rat primary afferent neurons: role of CaMKII and the effect of injury. (Tang Q, Bangaru ML, Kostic S, Pan B, Wu HE, Koopmeiners AS, Yu H, Fischer GJ, McCallum JB, Kwok WM, Hudmon A, Hogan QH) J Neurosci 2012 Aug 22;32(34):11737-49 PMID: 22915116 PMCID: PMC3723336 08/24/2012       20 Citations
  • Lentiviral gene transfer into the dorsal root ganglion of adult rats. (Yu H, Fischer G, Jia G, Reiser J, Park F, Hogan QH) Mol Pain 2011 Aug 23;7:63 PMID: 21861915 PMCID: PMC3179738 08/25/2011       28 Citations
  • Direct injection into the dorsal root ganglion: technical, behavioral, and histological observations. (Fischer G, Kostic S, Nakai H, Park F, Sapunar D, Yu H, Hogan Q) J Neurosci Methods 2011 Jul 15;199(1):43-55 PMID: 21540055 PMCID: PMC3742008 05/05/2011       36 Citations
  • Quantifying raft proteins in neonatal mouse brain by 'tube-gel' protein digestion label-free shotgun proteomics. (Yu H, Wakim B, Li M, Halligan B, Tint GS, Patel SB) Proteome Sci 2007 Sep 24;5:17 PMID: 17892558 PMCID: PMC2045652 09/26/2007    
  • Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice. (Yu H, Li M, Tint GS, Chen J, Xu G, Patel SB) BMC Dev Biol 2007 Apr 04;7:27 PMID: 17408495 PMCID: PMC1855921 04/06/2007       5 Citations
  • Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse. (Solcà C, Pandit B, Yu H, Tint GS, Patel SB) Mol Genet Metab 2007 May;91(1):7-14 PMID: 17197219 PMCID: PMC1852500 01/02/2007       6 Citations
  • The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. (Tint GS, Yu H, Shang Q, Xu G, Patel SB) J Lipid Res 2006 Jul;47(7):1535-41 PMID: 16651660 PMCID: PMC1488821 05/03/2006       60 Citations
  • Recent insights into the Smith-Lemli-Opitz syndrome. (Yu H, Patel SB) Clin Genet 2005 Nov;68(5):383-91 PMID: 16207203 PMCID: PMC1350989 10/07/2005       58 Citations
  • The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension. (Chen J, Batta A, Zheng S, Fitzgibbon WR, Ullian ME, Yu H, Tso P, Salen G, Patel SB) BMC Genet 2005 Jul 18;6:40 PMID: 16026620 PMCID: PMC1190168 07/20/2005       10 Citations
  • Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression. (Yu H, Wessels A, Tint GS, Patel SB) Brain Res Dev Brain Res 2005 Apr 21;156(1):46-60 PMID: 15862627 05/03/2005       11 Citations
  • A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. (Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, Salen G, Patel SB) BMC Med 2004 Mar 24;2:5 PMID: 15040800 PMCID: PMC394351 03/26/2004       104 Citations
  • Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. (Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB) BMC Dev Biol 2004 Feb 02;4:1 PMID: 15005800 PMCID: PMC341451 03/10/2004       19 Citations
  • The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats. (Yu H, Pandit B, Klett E, Lee MH, Lu K, Helou K, Ikeda I, Egashira N, Sato M, Klein R, Batta A, Salen G, Patel SB) BMC Cardiovasc Disord 2003 Jun 03;3:4 PMID: 12783625 PMCID: PMC165443 06/05/2003       29 Citations
  • Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8. (Lu K, Lee MH, Yu H, Zhou Y, Sandell SA, Salen G, Patel SB) J Lipid Res 2002 Apr;43(4):565-78 PMID: 11907139 PMCID: PMC1815568 03/22/2002       47 Citations
  • 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. (Fitzky BU, Moebius FF, Asaoka H, Waage-Baudet H, Xu L, Xu G, Maeda N, Kluckman K, Hiller S, Yu H, Batta AK, Shefer S, Chen T, Salen G, Sulik K, Simoni RD, Ness GC, Glossmann H, Patel SB, Tint GS) J Clin Invest 2001 Sep;108(6):905-15 PMID: 11560960 PMCID: PMC200927 09/19/2001       114 Citations
  • Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. (Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H, Kojima H, Allikmets R, Sakuma N, Pegoraro R, Srivastava AK, Salen G, Dean M, Patel SB) Nat Genet 2001 Jan;27(1):79-83 PMID: 11138003 PMCID: PMC1350991 01/04/2001       531 Citations
  • Spectrum of Delta(7)-dehydrocholesterol reductase mutations in patients with the Smith-Lemli-Opitz (RSH) syndrome. (Yu H, Lee MH, Starck L, Elias ER, Irons M, Salen G, Patel SB, Tint GS) Hum Mol Genet 2000 May 22;9(9):1385-91 PMID: 10814720 05/18/2000       78 Citations
  • Detection of a common mutation in the RSH or Smith-Lemli-Opitz syndrome by a PCR-RFLP assay: IVS8-G-->C is found in over sixty percent of US propositi. (Yu H, Tint GS, Salen G, Patel SB) Am J Med Genet 2000 Feb 14;90(4):347-50 PMID: 10710236 03/10/2000       44 Citations
  • Cyclic AMP-dependent phosphodiesterase isozyme-specific potentiation by protein kinase C in hypertrophic cardiomyopathic hamster hearts. (Yu H, Cai JJ, Lee HC) Mol Pharmacol 1996 Sep;50(3):549-55 PMID: 8794893 09/01/1996       12 Citations
  • Effect of protein kinase C on cyclic 3',5'-adenosine monophosphate-dependent phosphodiesterase in hypertrophic cardiomyopathic hamster hearts. (Lee HC, Cai JJ, Yu H) J Pharmacol Exp Ther 1994 Sep;270(3):1171-6 PMID: 7932168 09/01/1994       15 Citations
  • Developmental changes of protein kinase C and Gs alpha in hypertrophic cardiomyopathic hamster hearts. (Cai JJ, Yu H, Lee HC) J Lab Clin Med 1993 Nov;122(5):533-41 PMID: 8228571 11/01/1993       7 Citations
  • Last update: 12/14/2017
    jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6