Medical College of Wisconsin
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Lisa A. Cirillo PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration


Publications

  • Sequence-specific capture of protein-DNA complexes for mass spectrometric protein identification. (Wu CH, Chen S, Shortreed MR, Kreitinger GM, Yuan Y, Frey BL, Zhang Y, Mirza S, Cirillo LA, Olivier M, Smith LM) PLoS One 2011;6(10):e26217 PMID 22028835
  • Dynamic association of gammaherpesvirus DNA with core histone during de novo lytic infection of primary cells. (Mounce BC, Tsan FC, Kohler S, Cirillo LA, Tarakanova VL) Virology 2011 Dec 20;421(2):167-72 PMID 22018782
  • Gammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX. (Mounce BC, Tsan FC, Droit L, Kohler S, Reitsma JM, Cirillo LA, Tarakanova VL) Virology 2011 Nov 25;420(2):73-81 PMID 21943826
  • Stable chromatin binding prevents FoxA acetylation, preserving FoxA chromatin remodeling. (Kohler S, Cirillo LA) J Biol Chem 2010 Jan 1;285(1):464-72 PMID 19897491
  • Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1. (Hatta M, Liu F, Cirillo LA) Biochem Biophys Res Commun 2009 Feb 20;379(4):1005-8 PMID 19146829
  • Many forkheads in the road to regulation. Symposium on forkhead transcription factor networks in development, signalling and disease. (Cirillo LA, Barton MC) EMBO Rep 2008 Aug;9(8):721-4 PMID 18617889
  • Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts. (Horswill MA, Narayan M, Warejcka DJ, Cirillo LA, Twining SS) Exp Eye Res 2008 Apr;86(4):586-600 PMID 18291368
  • Chromatin opening and stable perturbation of core histone:DNA contacts by FoxO1. (Hatta M, Cirillo LA) J Biol Chem 2007 Dec 7;282(49):35583-93 PMID 17923482
  • Specific interactions of the wing domains of FOXA1 transcription factor with DNA. (Cirillo LA, Zaret KS) J Mol Biol 2007 Feb 23;366(3):720-4 PMID 17189638
  • Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitro. (Taganov KD, Cuesta I, Daniel R, Cirillo LA, Katz RA, Zaret KS, Skalka AM) J Virol 2004 Jun;78(11):5848-55 PMID 15140982
  • Preparation of defined mononucleosomes, dinucleosomes, and nucleosome arrays in vitro and analysis of transcription factor binding. (Cirillo LA, Zaret KS) Methods Enzymol 2004;375:131-58 PMID 14870664
  • The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation. (Deng Z, Chen CJ, Chamberlin M, Lu F, Blobel GA, Speicher D, Cirillo LA, Zaret KS, Lieberman PM) Mol Cell Biol 2003 Apr;23(8):2633-44 PMID 12665567
  • Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. (Cirillo LA, Lin FR, Cuesta I, Friedman D, Jarnik M, Zaret KS) Mol Cell 2002 Feb;9(2):279-89 PMID 11864602
  • An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA. (Cirillo LA, Zaret KS) Mol Cell 1999 Dec;4(6):961-9 PMID 10635321
  • Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. (Cirillo LA, McPherson CE, Bossard P, Stevens K, Cherian S, Shim EY, Clark KL, Burley SK, Zaret KS) EMBO J 1998 Jan 2;17(1):244-54 PMID 9427758
  • Developmental regulation of alpha-fetoprotein expression in intestinal epithelial cells of transgenic mice. (Cirillo LA, Emerson JA, Vacher J, Tyner AL) Dev Biol 1995 Apr;168(2):395-405 PMID 7537233
  • The zonal expression of alpha-fetoprotein transgenes in the livers of adult mice. (Emerson JA, Vacher J, Cirillo LA, Tilghman SM, Tyner AL) Dev Dyn 1992 Sep;195(1):55-66 PMID 1284040
  • Grants and Awards

  • Transcriptional Regulation of Hepatocyte Differentiation and Function (#9207540 06/15/2012 - 04/30/2016) Sponsor: NIH Diabetes, Digestive and Kidney Diseases
  • Center of Excellence in Genomic Sciences: Sub-Contract (#9208022 07/01/2013 - 06/30/2014) Sponsor: Texas Biomedical Research Institute
  • Chromatin Binding and Remodeling by Foxo1 (#9203927 01/01/2006 - 12/31/2008) Sponsor: American Diabetes Association
  • Chromatin Remodeling During Liver Development (#9204133 07/10/2006 - 06/30/2011) Sponsor: NIH Diabetes, Digestive and Kidney Diseases
  • Cancer Center Infrastructure Grant (#9520181 11/01/2010 - 10/31/2016) PI of Misdirected Chromatin Remodeling as a Mechanism for Pax3FoxO1 Mediated Oncogeneis in Alveolar Rhabdomyosarcoma (#5520219)