Medical College of Wisconsin
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Stephanie Olivier-Van Stichelen PhD

Stephanie Olivier-Van Stichelen PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Biochemistry

image of /images/ORCIDiD_icon16x16.png   https://orcid.org/0000-0002-2033-5241

Member of the Cancer Center
Member of the Cardiovascular Center


I am willing to collaborate on research projects.

View Curriculum Vitae

Research Experience

  • Acetylglucosamine
  • Animals
  • Blotting, Western
  • Diet
  • Fasting
  • Female
  • Glucose
  • Glycosylation
  • Intestinal Mucosa
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Models, Biological
  • N-Acetylglucosaminyltransferases
  • Phosphorylation
  • Protein Processing, Post-Translational
  • Signal Transduction
  • Wnt Signaling Pathway
  • X Chromosome Inactivation
  • beta Catenin
  • beta-N-Acetylhexosaminidases

    • Publications (33)

  • Studying the O-GlcNAcome of human placentas using banked tissue samples. (Luna S, Malard F, Pereckas M, Aoki M, Aoki K, Stichelen SO) Glycobiology 2024 Apr 10;34(4) PMID: 38253038 PMCID: PMC11005170 SCOPUS ID: 2-s2.0-85190109720 01/23/2024    
  • O-GlcNAcylation regulates OTX2's proteostasis. (Wulff-Fuentes E, Boakye J, Kroenke K, Berendt RR, Martinez-Morant C, Pereckas M, Hanover JA, Olivier-Van Stichelen S) iScience 2023 Nov 17;26(11):108184 PMID: 38026167 PMCID: PMC10661118 SCOPUS ID: 2-s2.0-85175489896 11/29/2023       1 Citation
  • O-GlcNAcylation regulates OTX2’s proteostasis (Wulff-Fuentes E, Boakye J, Kroenke K, Berendt RR, Martinez-Morant C, Pereckas M, Hanover JA, Olivier-Van Stichelen S) iScience 17 November 2023;26(11) SCOPUS ID: 2-s2.0-85175489896 11/17/2023       1 Citation
  • Non-Nutritive Sweeteners Acesulfame Potassium and Sucralose Are Competitive Inhibitors of the Human P-glycoprotein/Multidrug Resistance Protein 1 (PGP/MDR1). (Danner L, Malard F, Valdes R, Olivier-Van Stichelen S) Nutrients 2023 Feb 23;15(5) PMID: 36904118 PMCID: PMC10005754 SCOPUS ID: 2-s2.0-85149772752 03/12/2023       1 Citation
  • O-GlcNAc transferase contributes to sex-specific placental deregulation in gestational diabetes. (Cui Y, Cruz M, Palatnik A, Olivier-Van Stichelen S) Placenta 2023 Jan;131:1-12 PMID: 36442303 PMCID: PMC9839643 SCOPUS ID: 2-s2.0-85142764152 11/29/2022       7 Citations
  • The O-GlcNAc cycling in neurodevelopment and associated diseases. (Wenzel DM, Olivier-Van Stichelen S) Biochem Soc Trans 2022 Dec 16;50(6):1693-1702 PMID: 36383066 PMCID: PMC10462390 SCOPUS ID: 2-s2.0-85144232323 11/17/2022       4 Citations
  • Editorial: Glycotherapeutics: Design, synthesis, function and biomedical application of agents emerging from glycochemistry and glycobiology. (Sheikh MO, Capicciotti CJ, Olivier-Van Stichelen S) Front Mol Biosci 2022;9:1012485 PMID: 36158575 PMCID: PMC9493436 SCOPUS ID: 2-s2.0-85138548518 09/27/2022    
  • EpyNN: Educational python for Neural Networks (Malard F, Danner L, Rouzies E, Meyer JG, Lescop E, Olivier-Van Stichelen S) SoftwareX July 2022;19 SCOPUS ID: 2-s2.0-85133927427 07/01/2022    
  • Find out if your protein is O-GlcNAc modified: The O-GlcNAc database. (Olivier-Van Stichelen S, Malard F, Berendt R, Wulff-Fuentes E, Danner L) FASEB J 2022 May;36 Suppl 1 PMID: 35555657 SCOPUS ID: 2-s2.0-85130007238 05/14/2022    
  • OTX2's Dual Mode of Degradation is Regulated by O-GlcNAcylation. (Wulff Fuentes EA, Boakye J, Pereckas M, Berendt R, Hanover JA, Olivier-Van Stichelen S) FASEB J 2022 May;36 Suppl 1 PMID: 35554496 SCOPUS ID: 2-s2.0-85130072717 05/14/2022    
  • O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells. (Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S) Endocrinology 2021 Dec 01;162(12) PMID: 34418053 PMCID: PMC8482966 SCOPUS ID: 2-s2.0-85117209862 08/22/2021       1 Citation
  • Automatization and self-maintenance of the O-GlcNAcome catalog: a smart scientific database. (Malard F, Wulff-Fuentes E, Berendt RR, Didier G, Olivier-Van Stichelen S) Database (Oxford) 2021 Jul 19;2021 PMID: 34279596 PMCID: PMC8288053 SCOPUS ID: 2-s2.0-85111799484 07/20/2021       7 Citations
  • The human O-GlcNAcome database and meta-analysis. (Wulff-Fuentes E, Berendt RR, Massman L, Danner L, Malard F, Vora J, Kahsay R, Olivier-Van Stichelen S) Sci Data 2021 Jan 21;8(1):25 PMID: 33479245 PMCID: PMC7820439 SCOPUS ID: 2-s2.0-85099969999 01/23/2021       115 Citations
  • Reply. (Palatnik A, Moosreiner A, Olivier-Van Stichelen S) Am J Obstet Gynecol 2020 Nov;223(5):777 PMID: 32800821 SCOPUS ID: 2-s2.0-85090478607 08/18/2020    
  • Reply. (Palatnik A, Moosreiner A, Olivier-Van Stichelen S) Am J Obstet Gynecol 2020 Dec;223(6):953 PMID: 32795429 SCOPUS ID: 2-s2.0-85090478607 08/17/2020    
  • Consumption of non-nutritive sweeteners during pregnancy. (Palatnik A, Moosreiner A, Olivier-Van Stichelen S) Am J Obstet Gynecol 2020 Aug;223(2):211-218 PMID: 32275895 SCOPUS ID: 2-s2.0-85084204967 04/11/2020       31 Citations
  • Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny's Metabolism and Microbiome. (Olivier-Van Stichelen S, Rother KI, Hanover JA) Front Microbiol 2019;10:1360 PMID: 31281295 PMCID: PMC6595049 SCOPUS ID: 2-s2.0-85069037426 07/10/2019       63 Citations
  • Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration. (Akan I, Olivier-Van Stichelen S, Bond MR, Hanover JA) J Neurochem 2018 Jan;144(1):7-34 PMID: 29049853 PMCID: PMC5735008 SCOPUS ID: 2-s2.0-85034243308 10/20/2017       58 Citations
  • Nutrient-driven O-linked N-acetylglucosamine (O-GlcNAc) cycling impacts neurodevelopmental timing and metabolism. (Olivier-Van Stichelen S, Wang P, Comly M, Love DC, Hanover JA) J Biol Chem 2017 Apr 14;292(15):6076-6085 PMID: 28246173 PMCID: PMC5391740 SCOPUS ID: 2-s2.0-85018506290 03/02/2017       56 Citations
  • Glucokinase expression is regulated by glucose through O-GlcNAc glycosylation. (Baldini SF, Steenackers A, Olivier-Van Stichelen S, Mir AM, Mortuaire M, Lefebvre T, Guinez C) Biochem Biophys Res Commun 2016 Sep 16;478(2):942-8 PMID: 27520373 SCOPUS ID: 2-s2.0-84995554965 08/16/2016       30 Citations
  • Silencing the Nucleocytoplasmic O-GlcNAc Transferase Reduces Proliferation, Adhesion, and Migration of Cancer and Fetal Human Colon Cell Lines. (Steenackers A, Olivier-Van Stichelen S, Baldini SF, Dehennaut V, Toillon RA, Le Bourhis X, El Yazidi-Belkoura I, Lefebvre T) Front Endocrinol (Lausanne) 2016;7:46 PMID: 27252680 PMCID: PMC4879930 SCOPUS ID: 2-s2.0-84975266611 06/03/2016       42 Citations
  • You are what you eat: O-linked N-acetylglucosamine in disease, development and epigenetics. (Olivier-Van Stichelen S, Hanover JA) Curr Opin Clin Nutr Metab Care 2015 Jul;18(4):339-45 PMID: 26049631 PMCID: PMC4479189 SCOPUS ID: 2-s2.0-84942800547 06/08/2015       40 Citations
  • X-inactivation normalizes O-GlcNAc transferase levels and generates an O-GlcNAc-depleted Barr body. (Olivier-Van Stichelen S, Hanover JA) Front Genet 2014;5:256 PMID: 25136351 PMCID: PMC4120696 SCOPUS ID: 2-s2.0-84906214579 08/20/2014       17 Citations
  • Chromosome imbalance as a driver of sex disparity in disease. (Abramowitz LK, Olivier-Van Stichelen S, Hanover JA) J Genomics 2014;2:77-88 PMID: 25031659 PMCID: PMC4091450 07/18/2014    
  • X marks the spot: does it matter that O-GlcNAc transferase is an X-linked gene? (Olivier-Van Stichelen S, Abramowitz LK, Hanover JA) Biochem Biophys Res Commun 2014 Oct 17;453(2):201-7 PMID: 24960196 PMCID: PMC4253714 SCOPUS ID: 2-s2.0-84906216635 06/25/2014       21 Citations
  • O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. (Olivier-Van Stichelen S, Dehennaut V, Buzy A, Zachayus JL, Guinez C, Mir AM, El Yazidi-Belkoura I, Copin MC, Boureme D, Loyaux D, Ferrara P, Lefebvre T) FASEB J 2014 Aug;28(8):3325-38 PMID: 24744147 PMCID: PMC4101651 SCOPUS ID: 2-s2.0-84905216343 04/20/2014       113 Citations
  • Antibodies and activity measurements for the detection of O-GlcNAc transferase and assay of its substrate, UDP-GlcNAc. (Lefebvre T, Drougat L, Olivier-Van Stichelen S, Michalski JC, Vercoutter-Edouart AS) Methods Mol Biol 2013;1022:147-59 PMID: 23765660 SCOPUS ID: 2-s2.0-84880499724 06/15/2013       5 Citations
  • Insulin signaling controls the expression of O-GlcNAc transferase and its interaction with lipid microdomains. (Perez-Cervera Y, Dehennaut V, Aquino Gil M, Guedri K, Solórzano Mata CJ, Olivier-Van Stichelen S, Michalski JC, Foulquier F, Lefebvre T) FASEB J 2013 Sep;27(9):3478-86 PMID: 23689613 SCOPUS ID: 2-s2.0-84883416868 05/22/2013       40 Citations
  • Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition. (Drougat L, Olivier-Van Stichelen S, Mortuaire M, Foulquier F, Lacoste AS, Michalski JC, Lefebvre T, Vercoutter-Edouart AS) Biochim Biophys Acta 2012 Dec;1820(12):1839-48 PMID: 22967762 SCOPUS ID: 2-s2.0-84866531577 09/13/2012       53 Citations
  • Serum-stimulated cell cycle entry promotes ncOGT synthesis required for cyclin D expression. (Olivier-Van Stichelen S, Drougat L, Dehennaut V, El Yazidi-Belkoura I, Guinez C, Mir AM, Michalski JC, Vercoutter-Edouart AS, Lefebvre T) Oncogenesis 2012 Dec 10;1(12):e36 PMID: 23552487 PMCID: PMC3545199 SCOPUS ID: 2-s2.0-84871950193 01/01/2012       43 Citations
  • The hexosamine biosynthetic pathway and O-GlcNAcylation drive the expression of β-catenin and cell proliferation. (Olivier-Van Stichelen S, Guinez C, Mir AM, Perez-Cervera Y, Liu C, Michalski JC, Lefebvre T) Am J Physiol Endocrinol Metab 2012 Feb 15;302(4):E417-24 PMID: 22114026 SCOPUS ID: 2-s2.0-84863017903 11/25/2011       56 Citations
  • [Signaling and metabolic predispositions linked to the colorectal cancer]. (Olivier S, Mir AM, Michalski JC, Lefebvre T) Med Sci (Paris) 2011 May;27(5):514-20 PMID: 21609673 SCOPUS ID: 2-s2.0-79958697701 05/26/2011       2 Citations
  • Dysregulation of the nutrient/stress sensor O-GlcNAcylation is involved in the etiology of cardiovascular disorders, type-2 diabetes and Alzheimer's disease. (Lefebvre T, Dehennaut V, Guinez C, Olivier S, Drougat L, Mir AM, Mortuaire M, Vercoutter-Edouart AS, Michalski JC) Biochim Biophys Acta 2010 Feb;1800(2):67-79 PMID: 19732809 SCOPUS ID: 2-s2.0-77949283280 09/08/2009       100 Citations
    • Last update: 05/13/2024