Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Sunila Pradeep PhD

Sunila Pradeep PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Obstetrics and Gynecology
Division: Research and Advanced Education
Program: Medical Education and Research

Member of the Cancer Center


Publications

  • Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression. (Dalton HJ, Pradeep S, McGuire M, Hailemichael Y, Ma S, Lyons Y, Armaiz-Pena GN, Previs RA, Hansen JM, Rupaimoole R, Gonzalez-Villasana V, Cho MS, Wu SY, Mangala LS, Jennings NB, Hu W, Langley R, Mu H, Andreeff M, Bar-Eli M, Overwijk W, Ram P, Lopez-Berestein G, Coleman RL, Sood AK) Clin Cancer Res 2017 Nov 15;23(22):7034-7046 PMID: 28855350 PMCID: PMC5690831 09/01/2017    
  • Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. (Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK) Nat Commun 2017 08 21;8(1):310 PMID: 28827520 PMCID: PMC5566477 08/23/2017       23 Citations
  • Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens. (Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK) JCI Insight 2017 Aug 17;2(16) PMID: 28814667 PMCID: PMC5621917 08/18/2017    
  • Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer. (Hu Q, Hisamatsu T, Haemmerle M, Cho MS, Pradeep S, Rupaimoole R, Rodriguez-Aguayo C, Lopez-Berestein G, Wong STC, Sood AK, Afshar-Kharghan V) Clin Cancer Res 2017 Sep 15;23(18):5611-5621 PMID: 28611202 PMCID: PMC5600833 06/15/2017       6 Citations
  • Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) J Biol Chem 2017 05 26;292(21):8849 PMID: 28550135 PMCID: PMC5448113 05/28/2017    
  • Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer. (Rabinowicz N, Mangala LS, Brown KR, Checa-Rodriguez C, Castiel A, Moskovich O, Zarfati G, Trakhtenbrot L, Levy-Barda A, Jiang D, Rodriguez-Aguayo C, Pradeep S, van Praag Y, Lopez-Berestein G, David A, Novikov I, Huertas P, Rottapel R, Sood AK, Izraeli S) Oncotarget 2017 Apr 18;8(16):27380-27392 PMID: 28423708 PMCID: PMC5432342 04/21/2017    
  • Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies. (Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK) J Natl Cancer Inst 2017 07 01;109(7) PMID: 28376174 PMCID: PMC6059189 04/05/2017    
  • TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Aging (Albany NY) 2016 12 16;8(12):3507-3519 PMID: 27992857 PMCID: PMC5270683 12/20/2016       11 Citations
  • Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. (Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D) Cell Metab 2016 11 08;24(5):685-700 PMID: 27829138 11/10/2016       43 Citations
  • Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers. (Hatakeyama H, Wu SY, Lyons YA, Pradeep S, Wang W, Huang Q, Court KA, Liu T, Nie S, Rodriguez-Aguayo C, Shen F, Huang Y, Hisamatsu T, Mitamura T, Jennings N, Shim J, Dorniak PL, Mangala LS, Petrillo M, Petyuk VA, Schepmoes AA, Shukla AK, Torres-Lugo M, Lee JS, Rodland KD, Fagotti A, Lopez-Berestein G, Li C, Sood AK) Cell Rep 2016 11 01;17(6):1621-1631 PMID: 27806300 PMCID: PMC5123842 11/03/2016       3 Citations
  • Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GL, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK) JCI Insight 2016 10 20;1(17):e87754 PMID: 27777972 PMCID: PMC5070952 10/26/2016       8 Citations
  • Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. (Huang Y, Lichtenberger LM, Taylor M, Bottsford-Miller JN, Haemmerle M, Wagner MJ, Lyons Y, Pradeep S, Hu W, Previs RA, Hansen JM, Fang D, Dorniak PL, Filant J, Dial EJ, Shen F, Hatakeyama H, Sood AK) Mol Cancer Ther 2016 12;15(12):2894-2904 PMID: 27638860 PMCID: PMC5136300 09/18/2016       13 Citations
  • Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4. (Harjes U, Bridges E, Gharpure KM, Roxanis I, Sheldon H, Miranda F, Mangala LS, Pradeep S, Lopez-Berestein G, Ahmed A, Fielding B, Sood AK, Harris AL) Oncogene 2017 02 16;36(7):912-921 PMID: 27568980 PMCID: PMC5318662 08/30/2016       14 Citations
  • Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. (Miranda F, Mannion D, Liu S, Zheng Y, Mangala LS, Redondo C, Herrero-Gonzalez S, Xu R, Taylor C, Chedom DF, Karaminejadranjbar M, Albukhari A, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Salah E, Abdul Azeez KR, Elkins JM, Campo L, Myers KA, Klotz D, Bivona S, Dhar S, Bast RC Jr, Saya H, Choi HG, Gray NS, Fischer R, Kessler BM, Yau C, Sood AK, Motohara T, Knapp S, Ahmed AA) Cancer Cell 2016 08 08;30(2):273-289 PMID: 27478041 08/02/2016       29 Citations
  • Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer. (Chaluvally-Raghavan P, Jeong KJ, Pradeep S, Silva AM, Yu S, Liu W, Moss T, Rodriguez-Aguayo C, Zhang D, Ram P, Liu J, Lu Y, Lopez-Berestein G, Calin GA, Sood AK, Mills GB) Cell Rep 2016 05 17;15(7):1493-1504 PMID: 27160903 PMCID: PMC4914391 05/11/2016       21 Citations
  • FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. (Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK) J Clin Invest 2016 05 02;126(5):1885-96 PMID: 27064283 PMCID: PMC4855933 04/12/2016       27 Citations
  • A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. (Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK) Nat Commun 2016 Apr 04;7:11169 PMID: 27041221 PMCID: PMC4822037 04/05/2016       38 Citations
  • Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2. (Rytelewski M, Maleki Vareki S, Mangala LS, Romanow L, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Figueredo R, Ferguson PJ, Vincent M, Sood AK, Koropatnick JD) Oncotarget 2016 Apr 12;7(15):20825-39 PMID: 26959114 PMCID: PMC4991495 03/10/2016       5 Citations
  • Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer. (Dwivedi SK, Mustafi SB, Mangala LS, Jiang D, Pradeep S, Rodriguez-Aguayo C, Ling H, Ivan C, Mukherjee P, Calin GA, Lopez-Berestein G, Sood AK, Bhattacharya R) Oncotarget 2016 Mar 22;7(12):15093-104 PMID: 26918603 PMCID: PMC4924772 02/27/2016       29 Citations
  • Role of Increased n-acetylaspartate Levels in Cancer. (Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK) J Natl Cancer Inst 2016 Jan 26;108(6):djv426 PMID: 26819345 PMCID: PMC4849357 01/29/2016       15 Citations
  • Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. (Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK) Oncogene 2016 08 18;35(33):4312-20 PMID: 26725326 PMCID: PMC4931989 01/05/2016       27 Citations
  • Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. (Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs RA, Pradeep S, Wu SY, Ivan C, Ferracin M, Dennison JB, Millward NMZ, Nagaraja AS, Gharpure KM, McGuire M, Sam N, Armaiz-Pena GN, Sadaoui NC, Rodriguez-Aguayo C, Calin GA, Drapkin RI, Kovacs J, Mills GB, Zhang W, Lopez-Berestein G, Bhattacharya PK, Sood AK) Cell Rep 2015 Dec 22;13(11):2395-2402 PMID: 26686630 PMCID: PMC4691557 12/22/2015       40 Citations
  • Dual Metronomic Chemotherapy with Nab-Paclitaxel and Topotecan Has Potent Antiangiogenic Activity in Ovarian Cancer. (Previs RA, Armaiz-Pena GN, Lin YG, Davis AN, Pradeep S, Dalton HJ, Hansen JM, Merritt WM, Nick AM, Langley RR, Coleman RL, Sood AK) Mol Cancer Ther 2015 Dec;14(12):2677-86 PMID: 26516159 PMCID: PMC4674355 10/31/2015       6 Citations
  • Erythropoietin Stimulates Tumor Growth via EphB4. (Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK) Cancer Cell 2015 Nov 09;28(5):610-622 PMID: 26481148 PMCID: PMC4643364 10/21/2015       19 Citations
  • Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma. (Park YY, Sohn BH, Johnson RL, Kang MH, Kim SB, Shim JJ, Mangala LS, Kim JH, Yoo JE, Rodriguez-Aguayo C, Pradeep S, Hwang JE, Jang HJ, Lee HS, Rupaimoole R, Lopez-Berestein G, Jeong W, Park IS, Park YN, Sood AK, Mills GB, Lee JS) Hepatology 2016 Jan;63(1):159-72 PMID: 26389641 PMCID: PMC4881866 09/22/2015       22 Citations
  • Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. (Nagaraja AS, Dorniak PL, Sadaoui NC, Kang Y, Lin T, Armaiz-Pena G, Wu SY, Rupaimoole R, Allen JK, Gharpure KM, Pradeep S, Zand B, Previs RA, Hansen JM, Ivan C, Rodriguez-Aguayo C, Yang P, Lopez-Berestein G, Lutgendorf SK, Cole SW, Sood AK) Oncogene 2016 05 05;35(18):2390-7 PMID: 26257064 PMCID: PMC4749473 08/11/2015       20 Citations
  • Targeting c-MYC in Platinum-Resistant Ovarian Cancer. (Reyes-González JM, Armaiz-Peña GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarría-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejía PE) Mol Cancer Ther 2015 Oct;14(10):2260-9 PMID: 26227489 PMCID: PMC4596776 08/01/2015       18 Citations
  • Tumor T1 Relaxation Time for Assessing Response to Bevacizumab Anti-Angiogenic Therapy in a Mouse Ovarian Cancer Model. (Ravoori MK, Nishimura M, Singh SP, Lu C, Han L, Hobbs BP, Pradeep S, Choi HJ, Bankson JA, Sood AK, Kundra V) PLoS One 2015;10(6):e0131095 PMID: 26098849 PMCID: PMC4476738 06/23/2015       1 Citations
  • The ZNF304-integrin axis protects against anoikis in cancer. (Aslan B, Monroig P, Hsu MC, Pena GA, Rodriguez-Aguayo C, Gonzalez-Villasana V, Rupaimoole R, Nagaraja AS, Mangala S, Han HD, Yuca E, Wu SY, Ivan C, Moss TJ, Ram PT, Wang H, Gol-Chambers A, Ozkayar O, Kanlikilicer P, Fuentes-Mattei E, Kahraman N, Pradeep S, Ozpolat B, Tucker S, Hung MC, Baggerly K, Bartholomeusz G, Calin G, Sood AK, Lopez-Berestein G) Nat Commun 2015 Jun 17;6:7351 PMID: 26081979 PMCID: PMC4830335 06/18/2015       15 Citations
  • XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. (Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK) Clin Cancer Res 2015 Jul 15;21(14):3286-97 PMID: 25878333 PMCID: PMC4506247 04/17/2015       8 Citations
  • Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer. (Gonzalez-Villasana V, Fuentes-Mattei E, Ivan C, Dalton HJ, Rodriguez-Aguayo C, Fernandez-de Thomas RJ, Aslan B, Del C Monroig P, Velazquez-Torres G, Previs RA, Pradeep S, Kahraman N, Wang H, Kanlikilicer P, Ozpolat B, Calin G, Sood AK, Lopez-Berestein G) Clin Cancer Res 2015 May 01;21(9):2127-37 PMID: 25595279 PMCID: PMC4417466 01/18/2015       30 Citations
  • Anti-vascular therapies in ovarian cancer: moving beyond anti-VEGF approaches. (Choi HJ, Armaiz Pena GN, Pradeep S, Cho MS, Coleman RL, Sood AK) Cancer Metastasis Rev 2015 Mar;34(1):19-40 PMID: 25544368 PMCID: PMC4369424 12/30/2014       29 Citations
  • Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers. (Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB) Cancer Cell 2014 Dec 08;26(6):863-879 PMID: 25490449 PMCID: PMC4261159 12/10/2014       24 Citations
  • Differential platelet levels affect response to taxane-based therapy in ovarian cancer. (Bottsford-Miller J, Choi HJ, Dalton HJ, Stone RL, Cho MS, Haemmerle M, Nick AM, Pradeep S, Zand B, Previs RA, Pecot CV, Crane EK, Hu W, Lutgendorf SK, Afshar-Kharghan V, Sood AK) Clin Cancer Res 2015 Feb 01;21(3):602-10 PMID: 25473001 PMCID: PMC4315757 12/05/2014       37 Citations
  • Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK) Nat Commun 2014 Oct 29;5:5202 PMID: 25351346 PMCID: PMC4215647 10/30/2014       73 Citations
  • Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. (Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC) Nat Commun 2014 Oct 03;5:5092 PMID: 25277212 PMCID: PMC4185407 10/04/2014       32 Citations
  • Hematogenous metastasis of ovarian cancer: rethinking mode of spread. (Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK) Cancer Cell 2014 Jul 14;26(1):77-91 PMID: 25026212 PMCID: PMC4100212 07/16/2014       92 Citations
  • Clodronate inhibits tumor angiogenesis in mouse models of ovarian cancer. (Reusser NM, Dalton HJ, Pradeep S, Gonzalez-Villasana V, Jennings NB, Vasquez HG, Wen Y, Rupaimoole R, Nagaraja AS, Gharpure K, Miyake T, Huang J, Hu W, Lopez-Berestein G, Sood AK) Cancer Biol Ther 2014 Aug;15(8):1061-7 PMID: 24841852 PMCID: PMC4119073 05/21/2014       13 Citations
  • Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. (Gharpure KM, Chu KS, Bowerman CJ, Miyake T, Pradeep S, Mangala SL, Han HD, Rupaimoole R, Armaiz-Pena GN, Rahhal TB, Wu SY, Luft JC, Napier ME, Lopez-Berestein G, DeSimone JM, Sood AK) Mol Cancer Ther 2014 Jul;13(7):1750-7 PMID: 24755199 PMCID: PMC4090269 04/24/2014       16 Citations
  • Notch3 pathway alterations in ovarian cancer. (Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK) Cancer Res 2014 Jun 15;74(12):3282-93 PMID: 24743243 PMCID: PMC4058356 04/20/2014       25 Citations
  • 2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. (Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK) Nat Commun 2014 Mar 12;5:3459 PMID: 24619206 PMCID: PMC4112501 03/13/2014       52 Citations
  • Autocrine effects of tumor-derived complement. (Cho MS, Vasquez HG, Rupaimoole R, Pradeep S, Wu S, Zand B, Han HD, Rodriguez-Aguayo C, Bottsford-Miller J, Huang J, Miyake T, Choi HJ, Dalton HJ, Ivan C, Baggerly K, Lopez-Berestein G, Sood AK, Afshar-Kharghan V) Cell Rep 2014 Mar 27;6(6):1085-1095 PMID: 24613353 PMCID: PMC4084868 03/13/2014       52 Citations
  • Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib. (Huang J, Hu W, Bottsford-Miller J, Liu T, Han HD, Zand B, Pradeep S, Roh JW, Thanapprapasr D, Dalton HJ, Pecot CV, Rupaimoole R, Lu C, Fellman B, Urbauer D, Kang Y, Jennings NB, Huang L, Deavers MT, Broaddus R, Coleman RL, Sood AK) Clin Cancer Res 2014 Apr 01;20(7):1846-55 PMID: 24486585 PMCID: PMC3975695 02/04/2014       13 Citations
  • Targeting SRC and tubulin in mucinous ovarian carcinoma. (Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK) Clin Cancer Res 2013 Dec 01;19(23):6532-43 PMID: 24100628 PMCID: PMC3852199 10/09/2013       15 Citations
  • Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. (Kang Y, Hu W, Ivan C, Dalton HJ, Miyake T, Pecot CV, Zand B, Liu T, Huang J, Jennings NB, Rupaimoole R, Taylor M, Pradeep S, Wu SY, Lu C, Wen Y, Huang J, Liu J, Sood AK) J Natl Cancer Inst 2013 Oct 02;105(19):1485-95 PMID: 24062525 PMCID: PMC3787907 09/26/2013       66 Citations
  • A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. (Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM) Cancer Cell 2013 Aug 12;24(2):229-41 PMID: 23871637 PMCID: PMC3743050 07/23/2013       63 Citations
  • A new method for stranded whole transcriptome RNA-seq. (Miller DF, Yan PS, Buechlein A, Rodriguez BA, Yilmaz AS, Goel S, Lin H, Collins-Burow B, Rhodes LV, Braun C, Pradeep S, Rupaimoole R, Dalkilic M, Sood AK, Burow ME, Tang H, Huang TH, Liu Y, Rusch DB, Nephew KP) Methods 2013 Sep 15;63(2):126-34 PMID: 23557989 PMCID: PMC3739992 04/06/2013       30 Citations
  • IRL-1620, an endothelin-B receptor agonist, enhanced radiation induced reduction in tumor volume in Dalton's Lymphoma Ascites tumor model. (Gulati A, Sunila ES, Kuttan G) Arzneimittelforschung 2012 Jan;62(1):14-7 PMID: 22331757 02/15/2012       6 Citations
  • Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. (Sunila ES, Hamsa TP, Kuttan G) Pharm Biol 2011 Oct;49(10):1065-73 PMID: 21591821 05/20/2011       15 Citations
  • Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) J Biol Chem 2011 Feb 04;286(5):3540-51 PMID: 21059648 PMCID: PMC3030359 11/10/2010       30 Citations
  • Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. (Konson A, Pradeep S, Seger R) Cancer Res 2010 Aug 01;70(15):6247-57 PMID: 20610633 07/09/2010       26 Citations
  • Dynamized preparations in cell culture. (Sunila ES, Kuttan R, Preethi KC, Kuttan G) Evid Based Complement Alternat Med 2009 Jun;6(2):257-63 PMID: 18955237 PMCID: PMC2686624 10/29/2008    
  • Effect of homeopathic medicines on transplanted tumors in mice. (Es S, Kuttan G, Kc P, Kuttan R) Asian Pac J Cancer Prev 2007 Jul-Sep;8(3):390-4 PMID: 18159975 12/28/2007       13 Citations
  • Inhibition of chemically induced carcinogenesis by drugs used in homeopathic medicine. (Kumar KB, Sunila ES, Kuttan G, Preethi KC, Venugopal CN, Kuttan R) Asian Pac J Cancer Prev 2007 Jan-Mar;8(1):98-102 PMID: 17477781 05/05/2007       15 Citations
  • A preliminary study on antimetastatic activity of Thuja occidentalis L. in mice model. (Sunila ES, Kuttan G) Immunopharmacol Immunotoxicol 2006;28(2):269-80 PMID: 16873095 07/29/2006       24 Citations
  • Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice. (Sunila ES, Kuttan G) Int Immunopharmacol 2006 May;6(5):733-41 PMID: 16546703 03/21/2006       23 Citations
  • Protective effect of Thuja occidentalis against radiation-induced toxicity in mice. (Sunila ES, Kuttan G) Integr Cancer Ther 2005 Dec;4(4):322-8 PMID: 16282509 11/12/2005       13 Citations
  • Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies. (Pradeep CR, Sunila ES, Kuttan G) Integr Cancer Ther 2005 Dec;4(4):315-21 PMID: 16282508 11/12/2005       62 Citations
  • Protective effect of Piper longum fruit ethanolic extract on radiation induced damages in mice: a preliminary study. (Sunila ES, Kuttan G) Fitoterapia 2005 Dec;76(7-8):649-55 PMID: 16243448 10/26/2005       24 Citations
  • Immunomodulatory and antitumor activity of Piper longum Linn. and piperine. (Sunila ES, Kuttan G) J Ethnopharmacol 2004 Feb;90(2-3):339-46 PMID: 15013199 03/12/2004       259 Citations
  • Last update: 01/04/2019
    jenkins-FCD Prod-300 626508253d14e4184314fb9f66322a03a5906796