Medical College of Wisconsin
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Sunila Pradeep PhD

Sunila Pradeep PhD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Obstetrics and Gynecology
Division: Research and Advanced Education
Program: Medical Education and Research

Member of the Cancer Center
Member of the Cardiovascular Center
Member of the Center for Immunology

Publications (105)

  • Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model (Mittal S, Kumar S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S) STAR Protocols 21 June 2024;5(2) SCOPUS ID: 2-s2.0-85187377383 06/21/2024    
  • Preclinical activity of selinexor in combination with eribulin in uterine leiomyosarcoma. (Mittal S, Kadamberi IP, Chang H, Wang F, Kumar S, Tsaih SW, Walker CJ, Chaluvally-Raghavan P, Charlson J, Landesman Y, Pradeep S) Exp Hematol Oncol 2023 Sep 15;12(1):78 PMID: 37715291 PMCID: PMC10503035 SCOPUS ID: 2-s2.0-85171339411 09/16/2023    
  • Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. (LaFargue CJ, Amero P, Noh K, Mangala LS, Wen Y, Bayraktar E, Umamaheswaran S, Stur E, Dasari SK, Ivan C, Pradeep S, Yoo W, Lu C, Jennings NB, Vathipadiekal V, Hu W, Chelariu-Raicu A, Ku Z, Deng H, Xiong W, Choi HJ, Hu M, Kiyama T, Mao CA, Ali-Fehmi R, Birrer MJ, Liu J, Zhang N, Lopez-Berestein G, de Franciscis V, An Z, Sood AK) Nat Commun 2023 Apr 26;14(1):2407 PMID: 37100807 PMCID: PMC10133315 SCOPUS ID: 2-s2.0-85153918496 04/27/2023       8 Citations
  • RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2023 Mar 28;42(3):112228 PMID: 36884347 PMCID: PMC10233815 SCOPUS ID: 2-s2.0-85149682952 03/09/2023    
  • Metabolic Reprogramming in Tumor-Associated Macrophages in the Ovarian Tumor Microenvironment. (Kumar S, Mittal S, Gupta P, Singh M, Chaluvally-Raghavan P, Pradeep S) Cancers (Basel) 2022 Oct 25;14(21) PMID: 36358644 PMCID: PMC9656653 SCOPUS ID: 2-s2.0-85141848301 11/12/2022       8 Citations
  • Extracellular vesicle contents as non-invasive biomarkers in ovarian malignancies (McAlarnen LA, Gupta P, Singh R, Pradeep S, Chaluvally-Raghavan P) Molecular Therapy Oncolytics 15 September 2022;26:347-359 SCOPUS ID: 2-s2.0-85136664501 09/15/2022       2 Citations
  • Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA) Nat Commun 2022 Jun 10;13(1):3352 PMID: 35688808 PMCID: PMC9187678 SCOPUS ID: 2-s2.0-85131828825 06/11/2022       1 Citation
  • Optimized proximity ligation assay (PLA) for detection of RNA-protein complex interactions in cell lines. (George J, Mittal S, Kadamberi IP, Pradeep S, Chaluvally-Raghavan P) STAR Protoc 2022 Jun 17;3(2):101340 PMID: 35620072 PMCID: PMC9127197 SCOPUS ID: 2-s2.0-85130357879 05/28/2022       3 Citations
  • Correction to: Parashar et al. Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance (Cancers, (2022), 14, 958) (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers May-2 2022;14(10) SCOPUS ID: 2-s2.0-85129951244 05/01/2022       1 Citation
  • Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer. (Gupta P, Kadamberi IP, Mittal S, Tsaih SW, George J, Kumar S, Vijayan DK, Geethadevi A, Parashar D, Topchyan P, McAlarnen L, Volkman BF, Cui W, Zhang KYJ, Di Vizio D, Chaluvally-Raghavan P, Pradeep S) Adv Sci (Weinh) 2022 May;9(14):e2104452 PMID: 35289120 PMCID: PMC9108620 SCOPUS ID: 2-s2.0-85126251446 03/16/2022       25 Citations
  • Patient-Derived Ovarian Cancer Spheroids Rely on PI3K-AKT Signaling Addiction for Cancer Stemness and Chemoresistance (Parashar D, Geethadevi A, Mittal S, McAlarnen LA, George J, Kadamberi IP, Gupta P, Uyar DS, Hopp EE, Drendel H, Bishop EA, Bradley WH, Bone KM, Rader JS, Pradeep S, Chaluvally-Raghavan P) Cancers February-2 2022;14(4) SCOPUS ID: 2-s2.0-85124460063 02/01/2022       12 Citations
  • Establishment of In Vivo Ovarian Cancer Mouse Models Using Intraperitoneal Tumor Cell Injection. (Mittal S, Gupta P, Chaluvally-Raghavan P, Pradeep S) Methods Mol Biol 2022;2424:247-254 PMID: 34918299 SCOPUS ID: 2-s2.0-85121752492 12/18/2021       4 Citations
  • RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2021 Nov 02;37(5):109934 PMID: 34731628 PMCID: PMC8675433 SCOPUS ID: 2-s2.0-85118477211 11/04/2021       31 Citations
  • CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance (Ma S, Mangala LS, Hu W, Bayaktar E, Yokoi A, Hu W, Pradeep S, Lee S, Piehowski PD, Villar-Prados A, Wu SY, McGuire MH, Lara OD, Rodriguez-Aguayo C, LaFargue CJ, Jennings NB, Rodland KD, Liu T, Kundra V, Ram PT, Ramakrishnan S, Lopez-Berestein G, Coleman RL, Sood AK) Cell Reports 17 August 2021;36(7) SCOPUS ID: 2-s2.0-85112794188 08/17/2021       21 Citations
  • Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. (Geethadevi A, Nair A, Parashar D, Ku Z, Xiong W, Deng H, Li Y, George J, McAllister DM, Sun Y, Kadamberi IP, Gupta P, Dwinell MB, Bradley WH, Rader JS, Rui H, Schwabe RF, Zhang N, Pradeep S, An Z, Chaluvally-Raghavan P) Cancer Res 2021 Oct 15;81(20):5336-5352 PMID: 34380633 PMCID: PMC8530981 SCOPUS ID: 2-s2.0-85116424540 08/13/2021       28 Citations
  • Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens. (Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK) JCI Insight 2021 Apr 08;6(7) PMID: 33793425 PMCID: PMC8119210 SCOPUS ID: 2-s2.0-85103808072 04/02/2021    
  • Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK) JCI Insight 2021 Apr 08;6(7) PMID: 33793423 PMCID: PMC8119196 SCOPUS ID: 2-s2.0-85103806720 04/02/2021    
  • Targeted biologic inhibition of both tumor cell-intrinsic and intercellular CLPTM1L/CRR9-mediated chemotherapeutic drug resistance. (Parashar D, Geethadevi A, McAllister D, Ebben J, Peterson FC, Jensen DR, Bishop E, Pradeep S, Volkman BF, Dwinell MB, Chaluvally-Raghavan P, James MA) NPJ Precis Oncol 2021 Mar 02;5(1):16 PMID: 33654182 PMCID: PMC7925570 SCOPUS ID: 2-s2.0-85109651282 03/04/2021       13 Citations
  • Emerging Role of Extracellular Vesicles in Immune Regulation and Cancer Progression. (Mittal S, Gupta P, Chaluvally-Raghavan P, Pradeep S) Cancers (Basel) 2020 Nov 28;12(12) PMID: 33260606 PMCID: PMC7760253 SCOPUS ID: 2-s2.0-85096847824 12/03/2020       41 Citations
  • Author Correction: Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression (Nature Communications, (2014), 5, 1, (5202), 10.1038/ncomms6202) (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK) Nature Communications 1 December 2020;11(1) SCOPUS ID: 2-s2.0-85085855730 12/01/2020       2 Citations
  • Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling. (Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cancer Res 2020 Dec 15;80(24):5554-5568 PMID: 33087324 PMCID: PMC7744365 SCOPUS ID: 2-s2.0-85100331032 10/23/2020       25 Citations
  • NRG1/ERBB3 Pathway Activation Induces Acquired Resistance to XPO1 Inhibitors. (Miyake TM, Pradeep S, Bayraktar E, Stur E, Handley KF, Wu SY, Rodriguez-Aguayo C, Lee JS, Lopez-Berestein G, Coleman RL, Sood AK) Mol Cancer Ther 2020 Aug;19(8):1727-1735 PMID: 32499298 PMCID: PMC7415525 SCOPUS ID: 2-s2.0-85089165001 06/06/2020       4 Citations
  • ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis. (Chen C, Gupta P, Parashar D, Nair GG, George J, Geethadevi A, Wang W, Tsaih SW, Bradley W, Ramchandran R, Rader JS, Chaluvally-Raghavan P, Pradeep S) Oncogene 2020 Apr;39(14):2921-2933 PMID: 32029900 PMCID: PMC7346970 SCOPUS ID: 2-s2.0-85079196544 02/08/2020       27 Citations
  • miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. (Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2019 Dec 24;29(13):4389-4406.e10 PMID: 31875548 PMCID: PMC7380555 SCOPUS ID: 2-s2.0-85076674271 12/26/2019       54 Citations
  • B Cells as an Immune-Regulatory Signature in Ovarian Cancer. (Gupta P, Chen C, Chaluvally-Raghavan P, Pradeep S) Cancers (Basel) 2019 Jun 26;11(7) PMID: 31248034 PMCID: PMC6678944 SCOPUS ID: 2-s2.0-85068665327 06/30/2019       35 Citations
  • GnRH-R-Targeted Lytic Peptide Sensitizes BRCA Wild-type Ovarian Cancer to PARP Inhibition. (Ma S, Pradeep S, Villar-Prados A, Wen Y, Bayraktar E, Mangala LS, Kim MS, Wu SY, Hu W, Rodriguez-Aguayo C, Leuschner C, Liang X, Ram PT, Schlacher K, Coleman RL, Sood AK) Mol Cancer Ther 2019 May;18(5):969-979 PMID: 30926640 PMCID: PMC6497555 SCOPUS ID: 2-s2.0-85065508642 03/31/2019       13 Citations
  • PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer. (Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK) Mol Cancer Ther 2019 Jan;18(1):162-172 PMID: 30305341 PMCID: PMC6318044 SCOPUS ID: 2-s2.0-85059497097 10/12/2018       24 Citations
  • Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) Cell Physiol Biochem 2018;49(2):512-529 PMID: 30157491 SCOPUS ID: 2-s2.0-85052945008 08/30/2018       11 Citations
  • FABP4 as a key determinant of metastatic potential of ovarian cancer. (Gharpure KM, Pradeep S, Sans M, Rupaimoole R, Ivan C, Wu SY, Bayraktar E, Nagaraja AS, Mangala LS, Zhang X, Haemmerle M, Hu W, Rodriguez-Aguayo C, McGuire M, Mak CSL, Chen X, Tran MA, Villar-Prados A, Pena GA, Kondetimmanahalli R, Nini R, Koppula P, Ram P, Liu J, Lopez-Berestein G, Baggerly K, S Eberlin L, Sood AK) Nat Commun 2018 Jul 26;9(1):2923 PMID: 30050129 PMCID: PMC6062524 SCOPUS ID: 2-s2.0-85050737572 07/28/2018       146 Citations
  • Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK) JCI Insight 2018 Jun 07;3(11) PMID: 29889661 PMCID: PMC6124393 SCOPUS ID: 2-s2.0-85062251133 06/12/2018       1 Citation
  • Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens. (Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK) JCI Insight 2018 Jun 07;3(11) PMID: 29889660 PMCID: PMC6124403 SCOPUS ID: 2-s2.0-85062250334 06/12/2018       1 Citation
  • ADH1B promotes mesothelial clearance and ovarian cancer infiltration. (Gharpure KM, Lara OD, Wen Y, Pradeep S, LaFargue C, Ivan C, Rupaimoole R, Hu W, Mangala LS, Wu SY, Nagaraja AS, Baggerly K, Sood AK) Oncotarget 2018 May 18;9(38):25115-25126 PMID: 29861857 PMCID: PMC5982754 SCOPUS ID: 2-s2.0-85047209178 06/05/2018       22 Citations
  • Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction. (Allen JK, Armaiz-Pena GN, Nagaraja AS, Sadaoui NC, Ortiz T, Dood R, Ozcan M, Herder DM, Haemmerle M, Gharpure KM, Rupaimoole R, Previs RA, Wu SY, Pradeep S, Xu X, Han HD, Zand B, Dalton HJ, Taylor M, Hu W, Bottsford-Miller J, Moreno-Smith M, Kang Y, Mangala LS, Rodriguez-Aguayo C, Sehgal V, Spaeth EL, Ram PT, Wong STC, Marini FC, Lopez-Berestein G, Cole SW, Lutgendorf SK, De Biasi M, Sood AK) Cancer Res 2018 Jun 15;78(12):3233-3242 PMID: 29661830 PMCID: PMC6004256 SCOPUS ID: 2-s2.0-85048711132 04/18/2018       67 Citations
  • The role of tumor microenvironment in resistance to anti-angiogenic therapy. (Ma S, Pradeep S, Hu W, Zhang D, Coleman R, Sood A) F1000Res 2018;7:326 PMID: 29560266 PMCID: PMC5854986 SCOPUS ID: 2-s2.0-85044043459 03/22/2018       48 Citations
  • Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA) Nat Commun 2018 Feb 02;9(1):476 PMID: 29396402 PMCID: PMC5797184 SCOPUS ID: 2-s2.0-85041609909 02/06/2018       35 Citations
  • ERBB signaling in CTCs of ovarian cancer and glioblastoma. (Geethadevi A, Parashar D, Bishop E, Pradeep S, Chaluvally-Raghavan P) Genes Cancer 2017 Nov;8(11-12):746-751 PMID: 29321816 PMCID: PMC5755720 SCOPUS ID: 2-s2.0-85042923599 01/13/2018       18 Citations
  • The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy. (McKenzie JA, Mbofung RM, Malu S, Zhang M, Ashkin E, Devi S, Williams L, Tieu T, Peng W, Pradeep S, Xu C, Zorro Manrique S, Liu C, Huang L, Chen Y, Forget MA, Haymaker C, Bernatchez C, Satani N, Muller F, Roszik J, Kalra A, Heffernan T, Sood A, Hu J, Amaria R, Davis RE, Hwu P) J Natl Cancer Inst 2018 Jul 01;110(7):777-786 PMID: 29267866 PMCID: PMC6037061 SCOPUS ID: 2-s2.0-85049643812 12/22/2017       62 Citations
  • Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer. (Huang Y, Hu W, Huang J, Shen F, Sun Y, Ivan C, Pradeep S, Dood R, Haemmerle M, Jiang D, Mangala LS, Noh K, Hansen JM, Dalton HJ, Previs RA, Nagaraja AS, McGuire M, Jennings NB, Broaddus R, Coleman RL, Sood AK) Mol Cancer Ther 2018 Feb;17(2):464-473 PMID: 29237804 PMCID: PMC5805630 SCOPUS ID: 2-s2.0-85041463891 12/15/2017       5 Citations
  • Macrophage depletion through colony stimulating factor 1 receptor pathway blockade overcomes adaptive resistance to anti-VEGF therapy. (Lyons YA, Pradeep S, Wu SY, Haemmerle M, Hansen JM, Wagner MJ, Villar-Prados A, Nagaraja AS, Dood RL, Previs RA, Hu W, Zhao Y, Mak DH, Xiao Z, Melendez BD, Lizee GA, Mercado-Uribe I, Baggerly KA, Hwu P, Liu J, Overwijk WW, Coleman RL, Sood AK) Oncotarget 2017 Nov 14;8(57):96496-96505 PMID: 29228548 PMCID: PMC5722500 SCOPUS ID: 2-s2.0-85033796867 12/13/2017       49 Citations
  • Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis. (Noh K, Mangala LS, Han HD, Zhang N, Pradeep S, Wu SY, Ma S, Mora E, Rupaimoole R, Jiang D, Wen Y, Shahzad MMK, Lyons Y, Cho M, Hu W, Nagaraja AS, Haemmerle M, Mak CSL, Chen X, Gharpure KM, Deng H, Xiong W, Kingsley CV, Liu J, Jennings N, Birrer MJ, Bouchard RR, Lopez-Berestein G, Coleman RL, An Z, Sood AK) Cell Rep 2017 Dec 05;21(10):2785-2795 PMID: 29212026 PMCID: PMC5749980 SCOPUS ID: 2-s2.0-85038074957 12/07/2017       31 Citations
  • Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Mol Cell Neurosci 2018 Jan;86:65-71 PMID: 29180229 PMCID: PMC6996272 SCOPUS ID: 2-s2.0-85036596177 11/29/2017       34 Citations
  • MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels. (Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, DeMarzo AM, Sood AK, Zhang L, Dang CV) Cancer Res 2018 Jan 01;78(1):64-74 PMID: 29180471 PMCID: PMC5993051 SCOPUS ID: 2-s2.0-85040179207 11/29/2017       82 Citations
  • Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP). (Mitamura T, Pradeep S, McGuire M, Wu SY, Ma S, Hatakeyama H, Lyons YA, Hisamatsu T, Noh K, Villar-Prados A, Chen X, Ivan C, Rodriguez-Aguayo C, Hu W, Lopez-Berestein G, Coleman RL, Sood AK) Oncogene 2018 Feb 08;37(6):722-731 PMID: 29059175 PMCID: PMC6040890 SCOPUS ID: 2-s2.0-85041519424 10/24/2017       31 Citations
  • Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression. (Dalton HJ, Pradeep S, McGuire M, Hailemichael Y, Ma S, Lyons Y, Armaiz-Pena GN, Previs RA, Hansen JM, Rupaimoole R, Gonzalez-Villasana V, Cho MS, Wu SY, Mangala LS, Jennings NB, Hu W, Langley R, Mu H, Andreeff M, Bar-Eli M, Overwijk W, Ram P, Lopez-Berestein G, Coleman RL, Sood AK) Clin Cancer Res 2017 Nov 15;23(22):7034-7046 PMID: 28855350 PMCID: PMC5690831 SCOPUS ID: 2-s2.0-85034821972 09/01/2017       70 Citations
  • Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. (Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK) Nat Commun 2017 Aug 21;8(1):310 PMID: 28827520 PMCID: PMC5566477 SCOPUS ID: 2-s2.0-85027837141 08/23/2017       168 Citations
  • Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens. (Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK) JCI Insight 2017 Aug 17;2(16) PMID: 28814667 PMCID: PMC5621917 SCOPUS ID: 2-s2.0-85041827280 08/18/2017       34 Citations
  • Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer. (Hu Q, Hisamatsu T, Haemmerle M, Cho MS, Pradeep S, Rupaimoole R, Rodriguez-Aguayo C, Lopez-Berestein G, Wong STC, Sood AK, Afshar-Kharghan V) Clin Cancer Res 2017 Sep 15;23(18):5611-5621 PMID: 28611202 PMCID: PMC5600833 SCOPUS ID: 2-s2.0-85029472021 06/15/2017       51 Citations
  • Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) J Biol Chem 2017 May 26;292(21):8849 PMID: 28550135 PMCID: PMC5448113 SCOPUS ID: 2-s2.0-85048247833 05/28/2017    
  • Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer. (Rabinowicz N, Mangala LS, Brown KR, Checa-Rodriguez C, Castiel A, Moskovich O, Zarfati G, Trakhtenbrot L, Levy-Barda A, Jiang D, Rodriguez-Aguayo C, Pradeep S, van Praag Y, Lopez-Berestein G, David A, Novikov I, Huertas P, Rottapel R, Sood AK, Izraeli S) Oncotarget 2017 Apr 18;8(16):27380-27392 PMID: 28423708 PMCID: PMC5432342 SCOPUS ID: 2-s2.0-85017503134 04/21/2017       9 Citations
  • Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies. (Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK) J Natl Cancer Inst 2017 Jul 01;109(7) PMID: 28376174 PMCID: PMC6059189 SCOPUS ID: 2-s2.0-85016195907 04/05/2017       10 Citations
  • ADAMTS16 mutations sensitize ovarian cancer cells to platinumbased chemotherapy (Yasukawa M, Liu Y, Hu L, Cogdell D, Gharpure KM, Pradeep S, Nagaraja AS, Sood AK, Zhang W) Oncotarget 2017;8(51):88410-88420 SCOPUS ID: 2-s2.0-85031916481 01/01/2017       11 Citations
  • TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Aging (Albany NY) 2016 Dec 16;8(12):3507-3519 PMID: 27992857 PMCID: PMC5270683 SCOPUS ID: 2-s2.0-85010589813 12/20/2016       45 Citations
  • Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. (Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D) Cell Metab 2016 Nov 08;24(5):685-700 PMID: 27829138 PMCID: PMC7329194 SCOPUS ID: 2-s2.0-84994680371 11/10/2016       281 Citations
  • Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers. (Hatakeyama H, Wu SY, Lyons YA, Pradeep S, Wang W, Huang Q, Court KA, Liu T, Nie S, Rodriguez-Aguayo C, Shen F, Huang Y, Hisamatsu T, Mitamura T, Jennings N, Shim J, Dorniak PL, Mangala LS, Petrillo M, Petyuk VA, Schepmoes AA, Shukla AK, Torres-Lugo M, Lee JS, Rodland KD, Fagotti A, Lopez-Berestein G, Li C, Sood AK) Cell Rep 2016 Nov 01;17(6):1621-1631 PMID: 27806300 PMCID: PMC5123842 SCOPUS ID: 2-s2.0-84995654430 11/03/2016       20 Citations
  • Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy. (Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK) JCI Insight 2016 Oct 20;1(17):e87754 PMID: 27777972 PMCID: PMC5070952 SCOPUS ID: 2-s2.0-85055600619 10/26/2016       12 Citations
  • Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. (Huang Y, Lichtenberger LM, Taylor M, Bottsford-Miller JN, Haemmerle M, Wagner MJ, Lyons Y, Pradeep S, Hu W, Previs RA, Hansen JM, Fang D, Dorniak PL, Filant J, Dial EJ, Shen F, Hatakeyama H, Sood AK) Mol Cancer Ther 2016 Dec;15(12):2894-2904 PMID: 27638860 PMCID: PMC5136300 SCOPUS ID: 2-s2.0-85008312083 09/18/2016       40 Citations
  • Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4. (Harjes U, Bridges E, Gharpure KM, Roxanis I, Sheldon H, Miranda F, Mangala LS, Pradeep S, Lopez-Berestein G, Ahmed A, Fielding B, Sood AK, Harris AL) Oncogene 2017 Feb 16;36(7):912-921 PMID: 27568980 PMCID: PMC5318662 SCOPUS ID: 2-s2.0-84984620729 08/30/2016       53 Citations
  • ADAMTS16 mutations sensitize ovarian cancer cells to platinum-based chemotherapy. (Yasukawa M, Liu Y, Hu L, Cogdell D, Gharpure KM, Pradeep S, Nagaraja AS, Sood AK, Zhang W) Oncotarget 2017 Oct 24;8(51):88410-88420 PMID: 29179445 PMCID: PMC5687615 SCOPUS ID: 2-s2.0-85031916481 08/08/2016       11 Citations
  • Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. (Miranda F, Mannion D, Liu S, Zheng Y, Mangala LS, Redondo C, Herrero-Gonzalez S, Xu R, Taylor C, Chedom DF, Carrami EM, Albukhari A, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Salah E, Abdul Azeez KR, Elkins JM, Campo L, Myers KA, Klotz D, Bivona S, Dhar S, Bast RC Jr, Saya H, Choi HG, Gray NS, Fischer R, Kessler BM, Yau C, Sood AK, Motohara T, Knapp S, Ahmed AA) Cancer Cell 2016 Aug 08;30(2):273-289 PMID: 27478041 SCOPUS ID: 2-s2.0-84979768766 08/02/2016       134 Citations
  • Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer. (Chaluvally-Raghavan P, Jeong KJ, Pradeep S, Silva AM, Yu S, Liu W, Moss T, Rodriguez-Aguayo C, Zhang D, Ram P, Liu J, Lu Y, Lopez-Berestein G, Calin GA, Sood AK, Mills GB) Cell Rep 2016 May 17;15(7):1493-1504 PMID: 27160903 PMCID: PMC4914391 SCOPUS ID: 2-s2.0-84964941322 05/11/2016       76 Citations
  • FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. (Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK) J Clin Invest 2016 May 02;126(5):1885-96 PMID: 27064283 PMCID: PMC4855933 SCOPUS ID: 2-s2.0-84988489941 04/12/2016       95 Citations
  • A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. (Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK) Nat Commun 2016 Apr 04;7:11169 PMID: 27041221 PMCID: PMC4822037 SCOPUS ID: 2-s2.0-84962728482 04/05/2016       107 Citations
  • Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2. (Rytelewski M, Maleki Vareki S, Mangala LS, Romanow L, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Figueredo R, Ferguson PJ, Vincent M, Sood AK, Koropatnick JD) Oncotarget 2016 Apr 12;7(15):20825-39 PMID: 26959114 PMCID: PMC4991495 SCOPUS ID: 2-s2.0-84964755416 03/10/2016       8 Citations
  • Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer. (Dwivedi SK, Mustafi SB, Mangala LS, Jiang D, Pradeep S, Rodriguez-Aguayo C, Ling H, Ivan C, Mukherjee P, Calin GA, Lopez-Berestein G, Sood AK, Bhattacharya R) Oncotarget 2016 Mar 22;7(12):15093-104 PMID: 26918603 PMCID: PMC4924772 SCOPUS ID: 2-s2.0-84962911774 02/27/2016       62 Citations
  • Role of Increased n-acetylaspartate Levels in Cancer. (Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK) J Natl Cancer Inst 2016 Jan 26;108(6):djv426 PMID: 26819345 PMCID: PMC4849357 SCOPUS ID: 2-s2.0-84977070436 01/29/2016       46 Citations
  • Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. (Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK) Oncogene 2016 Aug 18;35(33):4312-20 PMID: 26725326 PMCID: PMC4931989 SCOPUS ID: 2-s2.0-84953238221 01/05/2016       78 Citations
  • Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. (Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs RA, Pradeep S, Wu SY, Ivan C, Ferracin M, Dennison JB, Millward NMZ, Nagaraja AS, Gharpure KM, McGuire M, Sam N, Armaiz-Pena GN, Sadaoui NC, Rodriguez-Aguayo C, Calin GA, Drapkin RI, Kovacs J, Mills GB, Zhang W, Lopez-Berestein G, Bhattacharya PK, Sood AK) Cell Rep 2015 Dec 22;13(11):2395-2402 PMID: 26686630 PMCID: PMC4691557 SCOPUS ID: 2-s2.0-84952873436 12/22/2015       96 Citations
  • Dual Metronomic Chemotherapy with Nab-Paclitaxel and Topotecan Has Potent Antiangiogenic Activity in Ovarian Cancer. (Previs RA, Armaiz-Pena GN, Lin YG, Davis AN, Pradeep S, Dalton HJ, Hansen JM, Merritt WM, Nick AM, Langley RR, Coleman RL, Sood AK) Mol Cancer Ther 2015 Dec;14(12):2677-86 PMID: 26516159 PMCID: PMC4674355 SCOPUS ID: 2-s2.0-84958151163 10/31/2015       9 Citations
  • Erythropoietin Stimulates Tumor Growth via EphB4. (Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK) Cancer Cell 2015 Nov 09;28(5):610-622 PMID: 26481148 PMCID: PMC4643364 SCOPUS ID: 2-s2.0-84946552470 10/21/2015       72 Citations
  • Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma. (Park YY, Sohn BH, Johnson RL, Kang MH, Kim SB, Shim JJ, Mangala LS, Kim JH, Yoo JE, Rodriguez-Aguayo C, Pradeep S, Hwang JE, Jang HJ, Lee HS, Rupaimoole R, Lopez-Berestein G, Jeong W, Park IS, Park YN, Sood AK, Mills GB, Lee JS) Hepatology 2016 Jan;63(1):159-72 PMID: 26389641 PMCID: PMC4881866 SCOPUS ID: 2-s2.0-84952638769 09/22/2015       109 Citations
  • Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. (Nagaraja AS, Dorniak PL, Sadaoui NC, Kang Y, Lin T, Armaiz-Pena G, Wu SY, Rupaimoole R, Allen JK, Gharpure KM, Pradeep S, Zand B, Previs RA, Hansen JM, Ivan C, Rodriguez-Aguayo C, Yang P, Lopez-Berestein G, Lutgendorf SK, Cole SW, Sood AK) Oncogene 2016 May 05;35(18):2390-7 PMID: 26257064 PMCID: PMC4749473 SCOPUS ID: 2-s2.0-84938886946 08/11/2015       72 Citations
  • Targeting c-MYC in Platinum-Resistant Ovarian Cancer. (Reyes-González JM, Armaiz-Peña GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarría-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejía PE) Mol Cancer Ther 2015 Oct;14(10):2260-9 PMID: 26227489 PMCID: PMC4596776 SCOPUS ID: 2-s2.0-84946772115 08/01/2015       95 Citations
  • Tumor T1 Relaxation Time for Assessing Response to Bevacizumab Anti-Angiogenic Therapy in a Mouse Ovarian Cancer Model. (Ravoori MK, Nishimura M, Singh SP, Lu C, Han L, Hobbs BP, Pradeep S, Choi HJ, Bankson JA, Sood AK, Kundra V) PLoS One 2015;10(6):e0131095 PMID: 26098849 PMCID: PMC4476738 SCOPUS ID: 2-s2.0-84939202307 06/23/2015       10 Citations
  • The ZNF304-integrin axis protects against anoikis in cancer. (Aslan B, Monroig P, Hsu MC, Pena GA, Rodriguez-Aguayo C, Gonzalez-Villasana V, Rupaimoole R, Nagaraja AS, Mangala S, Han HD, Yuca E, Wu SY, Ivan C, Moss TJ, Ram PT, Wang H, Gol-Chambers A, Ozkayar O, Kanlikilicer P, Fuentes-Mattei E, Kahraman N, Pradeep S, Ozpolat B, Tucker S, Hung MC, Baggerly K, Bartholomeusz G, Calin G, Sood AK, Lopez-Berestein G) Nat Commun 2015 Jun 17;6:7351 PMID: 26081979 PMCID: PMC4830335 SCOPUS ID: 2-s2.0-84935895247 06/18/2015       44 Citations
  • XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. (Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK) Clin Cancer Res 2015 Jul 15;21(14):3286-97 PMID: 25878333 PMCID: PMC4506247 SCOPUS ID: 2-s2.0-84942912732 04/17/2015       36 Citations
  • Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer. (Gonzalez-Villasana V, Fuentes-Mattei E, Ivan C, Dalton HJ, Rodriguez-Aguayo C, Fernandez-de Thomas RJ, Aslan B, Del C Monroig P, Velazquez-Torres G, Previs RA, Pradeep S, Kahraman N, Wang H, Kanlikilicer P, Ozpolat B, Calin G, Sood AK, Lopez-Berestein G) Clin Cancer Res 2015 May 01;21(9):2127-37 PMID: 25595279 PMCID: PMC4417466 SCOPUS ID: 2-s2.0-84930651943 01/18/2015       62 Citations
  • Anti-vascular therapies in ovarian cancer: moving beyond anti-VEGF approaches. (Choi HJ, Armaiz Pena GN, Pradeep S, Cho MS, Coleman RL, Sood AK) Cancer Metastasis Rev 2015 Mar;34(1):19-40 PMID: 25544368 PMCID: PMC4369424 SCOPUS ID: 2-s2.0-84925457982 12/30/2014       74 Citations
  • Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers. (Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB) Cancer Cell 2014 Dec 08;26(6):863-879 PMID: 25490449 PMCID: PMC4261159 SCOPUS ID: 2-s2.0-84919477596 12/10/2014       44 Citations
  • Differential platelet levels affect response to taxane-based therapy in ovarian cancer. (Bottsford-Miller J, Choi HJ, Dalton HJ, Stone RL, Cho MS, Haemmerle M, Nick AM, Pradeep S, Zand B, Previs RA, Pecot CV, Crane EK, Hu W, Lutgendorf SK, Afshar-Kharghan V, Sood AK) Clin Cancer Res 2015 Feb 01;21(3):602-10 PMID: 25473001 PMCID: PMC4315757 SCOPUS ID: 2-s2.0-84961289449 12/05/2014       75 Citations
  • Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK) Nat Commun 2014 Oct 29;5:5202 PMID: 25351346 PMCID: PMC4215647 SCOPUS ID: 2-s2.0-84923276259 10/30/2014       146 Citations
  • Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. (Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC) Nat Commun 2014 Oct 03;5:5092 PMID: 25277212 PMCID: PMC4185407 SCOPUS ID: 2-s2.0-84920567826 10/04/2014       98 Citations
  • Hematogenous metastasis of ovarian cancer: rethinking mode of spread. (Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK) Cancer Cell 2014 Jul 14;26(1):77-91 PMID: 25026212 PMCID: PMC4100212 SCOPUS ID: 2-s2.0-84904265681 07/16/2014       242 Citations
  • Clodronate inhibits tumor angiogenesis in mouse models of ovarian cancer. (Reusser NM, Dalton HJ, Pradeep S, Gonzalez-Villasana V, Jennings NB, Vasquez HG, Wen Y, Rupaimoole R, Nagaraja AS, Gharpure K, Miyake T, Huang J, Hu W, Lopez-Berestein G, Sood AK) Cancer Biol Ther 2014 Aug;15(8):1061-7 PMID: 24841852 PMCID: PMC4119073 SCOPUS ID: 2-s2.0-84905487210 05/21/2014       32 Citations
  • Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. (Gharpure KM, Chu KS, Bowerman CJ, Miyake T, Pradeep S, Mangala SL, Han HD, Rupaimoole R, Armaiz-Pena GN, Rahhal TB, Wu SY, Luft JC, Napier ME, Lopez-Berestein G, DeSimone JM, Sood AK) Mol Cancer Ther 2014 Jul;13(7):1750-7 PMID: 24755199 PMCID: PMC4090269 SCOPUS ID: 2-s2.0-84904164280 04/24/2014       28 Citations
  • Notch3 pathway alterations in ovarian cancer. (Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK) Cancer Res 2014 Jun 15;74(12):3282-93 PMID: 24743243 PMCID: PMC4058356 SCOPUS ID: 2-s2.0-84903436202 04/20/2014       58 Citations
  • 2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. (Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK) Nat Commun 2014 Mar 12;5:3459 PMID: 24619206 PMCID: PMC4112501 SCOPUS ID: 2-s2.0-84896259886 03/13/2014       108 Citations
  • Autocrine effects of tumor-derived complement. (Cho MS, Vasquez HG, Rupaimoole R, Pradeep S, Wu S, Zand B, Han HD, Rodriguez-Aguayo C, Bottsford-Miller J, Huang J, Miyake T, Choi HJ, Dalton HJ, Ivan C, Baggerly K, Lopez-Berestein G, Sood AK, Afshar-Kharghan V) Cell Rep 2014 Mar 27;6(6):1085-1095 PMID: 24613353 PMCID: PMC4084868 SCOPUS ID: 2-s2.0-84897077965 03/13/2014       155 Citations
  • Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib. (Huang J, Hu W, Bottsford-Miller J, Liu T, Han HD, Zand B, Pradeep S, Roh JW, Thanapprapasr D, Dalton HJ, Pecot CV, Rupaimoole R, Lu C, Fellman B, Urbauer D, Kang Y, Jennings NB, Huang L, Deavers MT, Broaddus R, Coleman RL, Sood AK) Clin Cancer Res 2014 Apr 01;20(7):1846-55 PMID: 24486585 PMCID: PMC3975695 SCOPUS ID: 2-s2.0-84898753092 02/04/2014       23 Citations
  • Targeting SRC and tubulin in mucinous ovarian carcinoma. (Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK) Clin Cancer Res 2013 Dec 01;19(23):6532-43 PMID: 24100628 PMCID: PMC3852199 SCOPUS ID: 2-s2.0-84890288888 10/09/2013       33 Citations
  • Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. (Kang Y, Hu W, Ivan C, Dalton HJ, Miyake T, Pecot CV, Zand B, Liu T, Huang J, Jennings NB, Rupaimoole R, Taylor M, Pradeep S, Wu SY, Lu C, Wen Y, Huang J, Liu J, Sood AK) J Natl Cancer Inst 2013 Oct 02;105(19):1485-95 PMID: 24062525 PMCID: PMC3787907 SCOPUS ID: 2-s2.0-84885440374 09/26/2013       151 Citations
  • A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. (Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM) Cancer Cell 2013 Aug 12;24(2):229-41 PMID: 23871637 PMCID: PMC3743050 SCOPUS ID: 2-s2.0-84881549640 07/23/2013       216 Citations
  • A new method for stranded whole transcriptome RNA-seq. (Miller DF, Yan PS, Buechlein A, Rodriguez BA, Yilmaz AS, Goel S, Lin H, Collins-Burow B, Rhodes LV, Braun C, Pradeep S, Rupaimoole R, Dalkilic M, Sood AK, Burow ME, Tang H, Huang TH, Liu Y, Rusch DB, Nephew KP) Methods 2013 Sep 15;63(2):126-34 PMID: 23557989 PMCID: PMC3739992 SCOPUS ID: 2-s2.0-84885171004 04/06/2013       40 Citations
  • IRL-1620, an endothelin-B receptor agonist, enhanced radiation induced reduction in tumor volume in Dalton's Lymphoma Ascites tumor model. (Gulati A, Sunila ES, Kuttan G) Arzneimittelforschung 2012 Jan;62(1):14-7 PMID: 22331757 SCOPUS ID: 2-s2.0-84858729714 02/15/2012       11 Citations
  • Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. (Sunila ES, Hamsa TP, Kuttan G) Pharm Biol 2011 Oct;49(10):1065-73 PMID: 21591821 SCOPUS ID: 2-s2.0-80053056902 05/20/2011       29 Citations
  • Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) J Biol Chem 2011 Feb 04;286(5):3540-51 PMID: 21059648 PMCID: PMC3030359 SCOPUS ID: 2-s2.0-79952790515 11/10/2010       33 Citations
  • Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. (Konson A, Pradeep S, Seger R) Cancer Res 2010 Aug 01;70(15):6247-57 PMID: 20610633 SCOPUS ID: 2-s2.0-77955386926 07/09/2010       33 Citations
  • Dynamized preparations in cell culture. (Sunila ES, Kuttan R, Preethi KC, Kuttan G) Evid Based Complement Alternat Med 2009 Jun;6(2):257-63 PMID: 18955237 PMCID: PMC2686624 SCOPUS ID: 2-s2.0-70349482558 10/29/2008       32 Citations
  • Effect of homeopathic medicines on transplanted tumors in mice. (Es S, Kuttan G, Kc P, Kuttan R) Asian Pac J Cancer Prev 2007;8(3):390-4 PMID: 18159975 SCOPUS ID: 2-s2.0-44449133829 12/28/2007       22 Citations
  • Inhibition of chemically induced carcinogenesis by drugs used in homeopathic medicine. (Kumar KB, Sunila ES, Kuttan G, Preethi KC, Venugopal CN, Kuttan R) Asian Pac J Cancer Prev 2007;8(1):98-102 PMID: 17477781 SCOPUS ID: 2-s2.0-34547751934 05/05/2007       23 Citations
  • A preliminary study on antimetastatic activity of Thuja occidentalis L. in mice model. (Sunila ES, Kuttan G) Immunopharmacol Immunotoxicol 2006;28(2):269-80 PMID: 16873095 SCOPUS ID: 2-s2.0-33746798088 07/29/2006       37 Citations
  • Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice. (Sunila ES, Kuttan G) Int Immunopharmacol 2006 May;6(5):733-41 PMID: 16546703 SCOPUS ID: 2-s2.0-33645021929 03/21/2006       35 Citations
  • Protective effect of Thuja occidentalis against radiation-induced toxicity in mice. (Sunila ES, Kuttan G) Integr Cancer Ther 2005 Dec;4(4):322-8 PMID: 16282509 SCOPUS ID: 2-s2.0-28144443382 11/12/2005       16 Citations
  • Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies. (Pradeep CR, Sunila ES, Kuttan G) Integr Cancer Ther 2005 Dec;4(4):315-21 PMID: 16282508 SCOPUS ID: 2-s2.0-28144462911 11/12/2005       84 Citations
  • Protective effect of Piper longum fruit ethanolic extract on radiation induced damages in mice: a preliminary study. (Sunila ES, Kuttan G) Fitoterapia 2005 Dec;76(7-8):649-55 PMID: 16243448 SCOPUS ID: 2-s2.0-28044460109 10/26/2005       33 Citations
  • Immunomodulatory and antitumor activity of Piper longum Linn. and piperine. (Sunila ES, Kuttan G) J Ethnopharmacol 2004 Feb;90(2-3):339-46 PMID: 15013199 SCOPUS ID: 2-s2.0-0842283177 03/12/2004       411 Citations
    • Last update: 03/19/2024