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Publications indexed to the term Genetic Engineering

1Two is better than one: advances in pathogen-boosted immunotherapy and adoptive T-cell therapy. (Xin G, Schauder DM, Zander R, Cui W) Immunotherapy 2017 09;9(10):837-849       1 Citation
1Cell-Intrinsic Barriers of T Cell-Based Immunotherapy. (Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA) Trends Mol Med 2016 12;22(12):1000-1011       26 Citations
1Engineering Hematopoietic Cells for Cancer Immunotherapy: Strategies to Address Safety and Toxicity Concerns. (Resetca D, Neschadim A, Medin JA) J Immunother 2016 09;39(7):249-59       5 Citations
1A Candida albicans Strain Expressing Mammalian Interleukin-17A Results in Early Control of Fungal Growth during Disseminated Infection. (Huppler AR, Whibley N, Woolford CA, Childs EE, He J, Biswas PS, McGeachy MJ, Mitchell AP, Gaffen SL) Infect Immun 2015 Sep;83(9):3684-92       2 Citations
1Evaluation of Bystander Cell Killing Effects in Suicide Gene Therapy of Cancer: Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis. (Sato T, Neschadim A, Nakagawa R, Yanagisawa T, Medin JA) Methods Mol Biol 2015;1317:55-67       2 Citations
1Lentiviral vectors in cancer immunotherapy. (Oldham RA, Berinstein EM, Medin JA) Immunotherapy 2015;7(3):271-84       23 Citations
2Agrochemical control of plant water use using engineered abscisic acid receptors. (Park SY, Peterson FC, Mosquna A, Yao J, Volkman BF, Cutler SR) Nature 2015 Apr 23;520(7548):545-8       118 Citations
2Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice. (Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ) BMC Genet 2014 Dec 05;15:135       13 Citations
2In vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infection. (Schroeder JA, Chen Y, Fang J, Wilcox DA, Shi Q) J Thromb Haemost 2014 Aug;12(8):1283-93       26 Citations
1Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways. (Wang JC, Felizardo TC, Au BC, Fowler DH, Dekaban GA, Medin JA) Virol J 2013 Jul 20;10:240       4 Citations
1Fed-batch cultivation of Escherichia coli expressed designer hepatitis C virus diagnostic intermediate and its evaluation. (Gurramkonda C, Talha SM, Gudi SK, Gogineni VR, Surya Sambasiva Rao KR) Biotechnol Appl Biochem 2012 Nov-Dec;59(6):437-44       3 Citations
1Kr├╝ppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract. (Blackmore MG, Wang Z, Lerch JK, Motti D, Zhang YP, Shields CB, Lee JK, Goldberg JL, Lemmon VP, Bixby JL) Proc Natl Acad Sci U S A 2012 May 08;109(19):7517-22       156 Citations
1Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer. (Neschadim A, Wang JC, Lavie A, Medin JA) Cancer Gene Ther 2012 May;19(5):320-7       18 Citations
1Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase. (Neschadim A, Wang JC, Sato T, Fowler DH, Lavie A, Medin JA) Mol Ther 2012 May;20(5):1002-13       15 Citations
2Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes. (Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW) Mucosal Immunol 2011 May;4(3):325-34       20 Citations
2Preventive effects of bexarotene and budesonide in a genetically engineered mouse model of small cell lung cancer. (Wang Y, Wen W, Yi Y, Zhang Z, Lubet RA, You M) Cancer Prev Res (Phila) 2009 Dec;2(12):1059-64       25 Citations
1Unmasking different mechanical and energetic roles for the small heat shock proteins CryAB and HSPB2 using genetically modified mouse hearts. (Pinz I, Robbins J, Rajasekaran NS, Benjamin IJ, Ingwall JS) FASEB J 2008 Jan;22(1):84-92       34 Citations
1Strategies for the use of site-specific recombinases in genome engineering. (Jones JR, Shelton KD, Magnuson MA) Methods Mol Med 2005;103:245-57       25 Citations
1Deregulated expression of the Myc cellular oncogene drives development of mouse "Burkitt-like" lymphomas from naive B cells. (Zhu D, Qi CF, Morse HC 3rd, Janz S, Stevenson FK) Blood 2005 Mar 01;105(5):2135-7       33 Citations
1Windows into development: historic, current, and future perspectives on transgenic zebrafish. (Udvadia AJ, Linney E) Dev Biol 2003 Apr 01;256(1):1-17       149 Citations
1Use of transgenic and knockout strategies in mice. (Ryan MJ, Sigmund CD) Semin Nephrol 2002 Mar;22(2):154-60       3 Citations
1Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination. (Cvetkovic B, Yang B, Williamson RA, Sigmund CD) J Biol Chem 2000 Jan 14;275(2):1073-8       42 Citations
1Role of the tetraheme cytochrome CymA in anaerobic electron transport in cells of Shewanella putrefaciens MR-1 with normal levels of menaquinone. (Myers JM, Myers CR) J Bacteriol 2000 Jan;182(1):67-75       162 Citations
1Retrovirus-mediated correction of the metabolic defect in cultured Farber disease cells. (Medin JA, Takenaka T, Carpentier S, Garcia V, Basile JP, Segui B, Andrieu-Abadie N, Auge N, Salvayre R, Levade T) Hum Gene Ther 1999 May 20;10(8):1321-9       27 Citations
1Two strong 5' splice sites and competing, suboptimal 3' splice sites involved in alternative splicing of human immunodeficiency virus type 1 RNA. (O'Reilly MM, McNally MT, Beemon KL) Virology 1995 Nov 10;213(2):373-85    
1Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae. (Medin JA, Hunt L, Gathy K, Evans RK, Coleman MS) Proc Natl Acad Sci U S A 1990 Apr;87(7):2760-4       66 Citations
1Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli. (Sigmund CD, Ettayebi M, Borden A, Morgan EA) Methods Enzymol 1988;164:673-90       161 Citations