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2 | Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation. (Fox JC, Tyler RC, Guzzo C, Tuinstra RL, Peterson FC, Lusso P, Volkman BF) ACS Chem Biol 2015 Nov 20;10(11):2580-8 22 Citations |
1 | Interplay of Electrostatics and Hydrophobic Effects in the Metamorphic Protein Human Lymphotactin. (Korkmaz EN, Volkman BF, Cui Q) J Phys Chem B 2015 Jul 30;119(30):9547-58 3 Citations |
1 | Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein. (Harvey SR, Porrini M, Tyler RC, MacPhee CE, Volkman BF, Barran PE) Phys Chem Chem Phys 2015 Apr 28;17(16):10538-50 15 Citations |
1 | Structural and agonist properties of XCL2, the other member of the C-chemokine subfamily. (Fox JC, Nakayama T, Tyler RC, Sander TL, Yoshie O, Volkman BF) Cytokine 2015 Feb;71(2):302-11 45 Citations |
1 | Dissecting the dynamic conformations of the metamorphic protein lymphotactin. (Harvey SR, Porrini M, Konijnenberg A, Clarke DJ, Tyler RC, Langridge-Smith PR, MacPhee CE, Volkman BF, Barran PE) J Phys Chem B 2014 Oct 30;118(43):12348-59 32 Citations |
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2 | An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity. (Tuinstra RL, Peterson FC, Elgin ES, Pelzek AJ, Volkman BF) Biochemistry 2007 Mar 13;46(10):2564-73 50 Citations |
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1 | Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer. (Stoeltzing O, Liu W, Reinmuth N, Fan F, Parikh AA, Bucana CD, Evans DB, Semenza GL, Ellis LM) Am J Pathol 2003 Sep;163(3):1001-11 146 Citations |
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1 | Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies. (Cortes J, Albitar M, Thomas D, Giles F, Kurzrock R, Thibault A, Rackoff W, Koller C, O'Brien S, Garcia-Manero G, Talpaz M, Kantarjian H) Blood 2003 Mar 01;101(5):1692-7 215 Citations |
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1 | Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions. (Kuloğlu ES, McCaslin DR, Markley JL, Volkman BF) J Biol Chem 2002 May 17;277(20):17863-70 62 Citations |
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