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Ben George MD

Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Hematology and Oncology - Medicine
Program: Hematology

Member of the Cancer Center
Member of the Mellowes Center for Genomic Sciences and Precision Medicine

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Publications (82)

Efficacy and Safety of Trifluridine/Tipiracil-Containing Combinations in Colorectal Cancer and Other Advanced Solid Tumors: A Systematic Review. (Shitara K, Falcone A, Fakih MG, George B, Sundar R, Ranjan S, Van Cutsem E) Oncologist 2024 May 03;29(5):e601-e615 PMID: 38366864 PMCID: PMC11067808 SCOPUS ID: 2-s2.0-85192112434 02/17/2024

Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for Pancreatic Ductal Adenocarcinoma. (George B, Kudryashova O, Kravets A, Thalji S, Malarkannan S, Kurzrock R, Chernyavskaya E, Gusakova M, Kravchenko D, Tychinin D, Savin E, Alekseeva L, Butusova A, Bagaev A, Shin N, Brown JH, Sethi I, Wang D, Taylor B, McFall T, Kamgar M, Hall WA, Erickson B, Christians KK, Evans DB, Tsai S) Gastroenterology 2024 May;166(5):859-871.e3 PMID: 38280684 SCOPUS ID: 2-s2.0-85188891214 01/28/2024

Characterization of an oligometastatic state in patients with metastatic pancreatic adenocarcinoma undergoing systemic chemotherapy. (de Ortiz de Choudens S, Visotcky A, Banerjee A, Aldakkak M, Tsai S, Evans DB, Christians KK, Clarke CN, George B, Shreenivas A, Kamgar M, Chakrabarti S, Dua KS, Khan AH, Madhavan S, Erickson BA, Hall WA) Cancer Med 2023 Dec 22;13(1) PMID: 38140796 PMCID: PMC10807686 SCOPUS ID: 2-s2.0-85180644976 12/23/2023

ALK fusions in the pan-cancer setting: another tumor-agnostic target? (Shreenivas A, Janku F, Gouda MA, Chen HZ, George B, Kato S, Kurzrock R) NPJ Precis Oncol 2023 Sep 29;7(1):101 PMID: 37773318 PMCID: PMC10542332 SCOPUS ID: 2-s2.0-85173930134 09/29/2023 7 Citations

A Paradigm Shift in Primary Liver Cancer Therapy Utilizing Genomics, Molecular Biomarkers, and Artificial Intelligence. (Moroney J, Trivella J, George B, White SB) Cancers (Basel) 2023 May 17;15(10) PMID: 37345129 PMCID: PMC10216313 SCOPUS ID: 2-s2.0-85160713805 06/22/2023 1 Citation

Effects of prior therapies on outcomes with trifluridine/tipiracil in patients with metastatic gastric/gastroesophageal junction cancer in a randomized phase III trial (TAGS). (Shitara K, George B, Taieb J, Sundar R, Fakih MG, Makris L, Benhadji KA, Ghidini M) J Cancer Res Clin Oncol 2023 Sep;149(11):9361-9374 PMID: 37213030 PMCID: PMC10374776 SCOPUS ID: 2-s2.0-85160105116 05/22/2023

Definitive Chemoradiation Associated with Improved Survival Outcomes in Patients with Synchronous Oligometastatic Esophageal Cancer. (Matoska T, Banerjee A, Shreenivas A, Jurkowski L, Shukla ME, Gore EM, Linsky P, Gasparri M, George B, Johnstone C, Johnstone D, Puckett LL) Cancers (Basel) 2023 Apr 28;15(9) PMID: 37173988 PMCID: PMC10177457 SCOPUS ID: 2-s2.0-85159164697 05/13/2023 2 Citations

Biliary Adverse Events During Neoadjuvant Therapy for Pancreatic Cancer. (Thalji SZ, Fernando D, Dua KS, Madhavan S, Chisholm P, Smith ZL, Aldakkak M, Christians KK, Clarke CN, George B, Kamgar M, Erickson BA, Hall WA, Evans DB, Tsai S) Ann Surg 2023 Dec 01;278(6):e1224-e1231 PMID: 37078282 SCOPUS ID: 2-s2.0-85176508848 04/20/2023 1 Citation

Neoadjuvant chemotherapy for pancreatic cancer: Quality over quantity. (Thalji SZ, Aldakkak M, Christians KK, Clarke CN, George B, Kamgar M, Erickson BA, Hall WA, Chisholm P, Kulkarni N, Doucette S, Evans DB, Tsai S) J Surg Oncol 2023 Jul;128(1):41-50 PMID: 36960919 SCOPUS ID: 2-s2.0-85152449940 03/25/2023 2 Citations

ASO Visual Abstract: CA19-9 Response to First-Line Neoadjuvant FOLFIRINOX and Second-Line Gemcitabine/ nab-Paclitaxel for Patients with Operable Pancreatic Cancer. (Thalji SZ, Kamgar M, George B, Aldakkak M, Christians KK, Clarke CN, Erickson BA, Hall WA, Tolat PP, Smith ZL, Evans DB, Tsai S) Ann Surg Oncol 2023 May;30(5):3022 PMID: 36877324 SCOPUS ID: 2-s2.0-85152164746 03/07/2023

Comprehensive genomic profiling: Does timing matter? (Thapa B, Ahmed G, Szabo A, Kamgar M, Kilari D, Mehdi M, Menon S, Daniel S, Thompson J, Thomas J, George B) Front Oncol 2023;13:1025367 PMID: 36865796 PMCID: PMC9971445 SCOPUS ID: 2-s2.0-85149381128 03/04/2023 3 Citations

CA19-9 Response to First-Line Neoadjuvant FOLFIRINOX and Second-Line Gemcitabine/Nab-Paclitaxel for Patients with Operable Pancreatic Cancer. (Thalji SZ, Kamgar M, George B, Aldakkak M, Christians KK, Clarke CN, Erickson BA, Hall WA, Tolat PP, Smith ZL, Evans DB, Tsai S) Ann Surg Oncol 2023 May;30(5):3013-3021 PMID: 36788189 SCOPUS ID: 2-s2.0-85147934173 02/15/2023 1 Citation

Pooled safety analysis from phase III studies of trifluridine/tipiracil in patients with metastatic gastric or gastroesophageal junction cancer and metastatic colorectal cancer. (Van Cutsem E, Hochster H, Shitara K, Mayer R, Ohtsu A, Falcone A, Yoshino T, Doi T, Ilson DH, Arkenau HT, George B, Benhadji KA, Makris L, Tabernero J) ESMO Open 2022 Dec;7(6):100633 PMID: 36455504 PMCID: PMC9808443 SCOPUS ID: 2-s2.0-85143125406 12/02/2022 3 Citations

Telemedicine and health disparities: Association between patient characteristics and telemedicine, in-person, telephone and message-based care during the COVID-19 pandemic. (Tong L, George B, Crotty BH, Somai M, Taylor BW, Osinski K, Luo J) IPEM Transl 2022;3:100010 PMID: 36340828 PMCID: PMC9617798 11/08/2022

Phase 1 Randomized Trial of Stereotactic Body Radiation Therapy Followed by Nivolumab plus Ipilimumab or Nivolumab Alone in Advanced/Unresectable Hepatocellular Carcinoma. (Juloori A, Katipally RR, Lemons JM, Singh AK, Iyer R, Robbins JR, George B, Hall WA, Pitroda SP, Arif F, Fung J, Pillai A, Liao CY, Sharma M, Liauw SL) Int J Radiat Oncol Biol Phys 2023 Jan 01;115(1):202-213 PMID: 36108891 SCOPUS ID: 2-s2.0-85143996905 09/16/2022 26 Citations

Long term clinical outcomes and associated predictors of progression free survival in anal canal cancer. (Ponce SEB, Erickson BA, Hall WA, Bedi M, Martens MJ, Siker M, Thomas J, George B, Ludwig K, Peterson C, Ridolfi T, Longo JM) J Gastrointest Oncol 2022 Feb;13(1):185-196 PMID: 35284138 PMCID: PMC8899735 SCOPUS ID: 2-s2.0-85125562951 03/15/2022 1 Citation

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. (Das A, Sudhaman S, Morgenstern D, Coblentz A, Chung J, Stone SC, Alsafwani N, Liu ZA, Karsaneh OAA, Soleimani S, Ladany H, Chen D, Zatzman M, Cabric V, Nobre L, Bianchi V, Edwards M, Sambira Nahum LC, Ercan AB, Nabbi A, Constantini S, Dvir R, Yalon-Oren M, Campino GA, Caspi S, Larouche V, Reddy A, Osborn M, Mason G, Lindhorst S, Bronsema A, Magimairajan V, Opocher E, De Mola RL, Sabel M, Frojd C, Sumerauer D, Samuel D, Cole K, Chiaravalli S, Massimino M, Tomboc P, Ziegler DS, George B, Van Damme A, Hijiya N, Gass D, McGee RB, Mordechai O, Bowers DC, Laetsch TW, Lossos A, Blumenthal DT, Sarosiek T, Yen LY, Knipstein J, Bendel A, Hoffman LM, Luna-Fineman S, Zimmermann S, Scheers I, Nichols KE, Zapotocky M, Hansford JR, Maris JM, Dirks P, Taylor MD, Kulkarni AV, Shroff M, Tsang DS, Villani A, Xu W, Aronson M, Durno C, Shlien A, Malkin D, Getz G, Maruvka YE, Ohashi PS, Hawkins C, Pugh TJ, Bouffet E, Tabori U) Nat Med 2022 Jan;28(1):125-135 PMID: 34992263 PMCID: PMC8799468 SCOPUS ID: 2-s2.0-85122396368 01/08/2022 55 Citations

Progression-free survival 2: Is it ready for prime time? (George B, Kurzrock R) Cancer 2022 Apr 01;128(7):1361-1362 PMID: 34985767 SCOPUS ID: 2-s2.0-85122309248 01/06/2022 1 Citation

The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma. (George B, Kent M, Surinach A, Lamarre N, Cockrum P) Front Oncol 2021;11:754687 PMID: 34671563 PMCID: PMC8522478 SCOPUS ID: 2-s2.0-85117324695 10/22/2021 6 Citations

Updates and new directions in the use of radiation therapy for the treatment of pancreatic adenocarcinoma: dose, sensitization, and novel technology. (Hall WA, Kamgar M, Erickson BA, Ponce SB, Tsai S, Nevalainen MT, Christians KK, George B, Dua KS, Khan AH, Evans DB, Azmi AS) Cancer Metastasis Rev 2021 Sep;40(3):879-889 PMID: 34611794 PMCID: PMC8767496 SCOPUS ID: 2-s2.0-85116412346 10/07/2021 2 Citations

Evolution of Systemic Therapy in Metastatic Pancreatic Ductal Adenocarcinoma. (Kamgar M, Chakrabarti S, Shreenivas A, George B) Surg Oncol Clin N Am 2021 Oct;30(4):673-691 PMID: 34511189 SCOPUS ID: 2-s2.0-85111041414 09/14/2021 1 Citation

Precision Medicine and Pancreatic Cancer. (George B) Surg Oncol Clin N Am 2021 Oct;30(4):693-708 PMID: 34511190 SCOPUS ID: 2-s2.0-85115787135 09/14/2021

Telemedicine Adoption during the COVID-19 Pandemic: Gaps and Inequalities. (Luo J, Tong L, Crotty BH, Somai M, Taylor B, Osinski K, George B) Appl Clin Inform 2021 Aug;12(4):836-844 PMID: 34496419 PMCID: PMC8426040 SCOPUS ID: 2-s2.0-85114767728 09/09/2021 56 Citations

Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study. (Javle M, Borad MJ, Azad NS, Kurzrock R, Abou-Alfa GK, George B, Hainsworth J, Meric-Bernstam F, Swanton C, Sweeney CJ, Friedman CF, Bose R, Spigel DR, Wang Y, Levy J, Schulze K, Cuchelkar V, Patel A, Burris H) Lancet Oncol 2021 Sep;22(9):1290-1300 PMID: 34339623 SCOPUS ID: 2-s2.0-85113412076 08/03/2021 185 Citations

Germline evaluation of patients undergoing tumor genomic profiling: An academic cancer center's experience with implementing a germline review protocol. (Stachowiak S, Jacquart A, Zimmermann MT, George B, Dong H, Geurts JL) J Genet Couns 2021 Jun;30(3):900-910 PMID: 33754402 SCOPUS ID: 2-s2.0-85102814588 03/24/2021

DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells. (Chung J, Maruvka YE, Sudhaman S, Kelly J, Haradhvala NJ, Bianchi V, Edwards M, Forster VJ, Nunes NM, Galati MA, Komosa M, Deshmukh S, Cabric V, Davidson S, Zatzman M, Light N, Hayes R, Brunga L, Anderson ND, Ho B, Hodel KP, Siddaway R, Morrissy AS, Bowers DC, Larouche V, Bronsema A, Osborn M, Cole KA, Opocher E, Mason G, Thomas GA, George B, Ziegler DS, Lindhorst S, Vanan M, Yalon-Oren M, Reddy AT, Massimino M, Tomboc P, Van Damme A, Lossos A, Durno C, Aronson M, Morgenstern DA, Bouffet E, Huang A, Taylor MD, Villani A, Malkin D, Hawkins CE, Pursell ZF, Shlien A, Kunkel TA, Getz G, Tabori U) Cancer Discov 2021 May;11(5):1176-1191 PMID: 33355208 PMCID: PMC8223607 SCOPUS ID: 2-s2.0-85105299689 12/24/2020 34 Citations

Adjuvant therapy rates and overall survival in patients with localized pancreatic cancer from high Area Deprivation Index neighborhoods. (Mora J, Krepline AN, Aldakkak M, Christians KK, George B, Hall WA, Erickson BA, Kulkarni N, Evans DB, Tsai S) Am J Surg 2021 Jul;222(1):10-17 PMID: 33308823 SCOPUS ID: 2-s2.0-85097458297 12/15/2020 41 Citations

Bronchoalveolar lavage-based COVID-19 testing in patients with cancer. (Abid MB, Chhabra S, Buchan B, Graham MB, Abedin S, Thapa B, D'Souza A, George B, Hamadani M) Hematol Oncol Stem Cell Ther 2021 Mar;14(1):65-70 PMID: 33058787 PMCID: PMC7543702 SCOPUS ID: 2-s2.0-85092735525 10/16/2020 13 Citations

Total Neoadjuvant Therapy for Operable Pancreatic Cancer. (Kim RY, Christians KK, Aldakkak M, Clarke CN, George B, Kamgar M, Khan AH, Kulkarni N, Hall WA, Erickson BA, Evans DB, Tsai S) Ann Surg Oncol 2021 Apr;28(4):2246-2256 PMID: 33000372 SCOPUS ID: 2-s2.0-85091728559 10/02/2020 29 Citations

Cost-effectiveness analysis of universal germline testing for patients with pancreatic cancer. (Krepline AN, Geurts JL, George B, Kamgar M, Madhavan S, Erickson BA, Hall WA, Griffin MO, Evans DB, Tsai S, Kim RY) Surgery 2021 Mar;169(3):629-635 PMID: 32826069 SCOPUS ID: 2-s2.0-85089521842 08/23/2020 3 Citations

Radiographic patterns of first disease recurrence after neoadjuvant therapy and surgery for patients with resectable and borderline resectable pancreatic cancer. (Barnes CA, Aldakkak M, Christians KK, Clarke CN, Dua K, George B, Ritch PS, Kamgar M, Hall WA, Kulkarni N, Erickson BA, Evans DB, Tsai S) Surgery 2020 Sep;168(3):440-447 PMID: 32641278 SCOPUS ID: 2-s2.0-85087345792 07/10/2020 13 Citations

Open-label, Phase I Study of Nivolumab Combined with nab-Paclitaxel Plus Gemcitabine in Advanced Pancreatic Cancer. (Wainberg ZA, Hochster HS, Kim EJ, George B, Kaylan A, Chiorean EG, Waterhouse DM, Guiterrez M, Parikh A, Jain R, Carrizosa DR, Soliman HH, Lila T, Reiss DJ, Pierce DW, Bhore R, Banerjee S, Lyons L, Louis CU, Ong TJ, O'Dwyer PJ) Clin Cancer Res 2020 Sep 15;26(18):4814-4822 PMID: 32554514 SCOPUS ID: 2-s2.0-85096537917 06/20/2020 78 Citations

Value of Pretreatment ¹⁸F-fluorodeoxyglucose Positron Emission Tomography in Patients With Localized Pancreatic Cancer Treated With Neoadjuvant Therapy. (Barnes CA, Aldakkak M, Clarke CN, Christians KK, Bucklan D, Holt M, Tolat P, Ritch PS, George B, Hall WA, Erickson BA, Evans DB, Tsai S) Front Oncol 2020;10:500 PMID: 32363161 PMCID: PMC7180175 SCOPUS ID: 2-s2.0-85084152103 05/05/2020 10 Citations

Detection of germline variants using expanded multigene panels in patients with localized pancreatic cancer. (Krepline AN, Geurts JL, Akinola I, Christians KK, Clarke CN, George B, Ritch PS, Khan AH, Hall WA, Erickson BA, Griffin MO, Evans DB, Tsai S) HPB (Oxford) 2020 Dec;22(12):1745-1752 PMID: 32354656 SCOPUS ID: 2-s2.0-85083782398 05/02/2020 2 Citations

Impact of Neoadjuvant Chemoradiation on Pathologic Response in Patients With Localized Pancreatic Cancer. (Wittmann D, Hall WA, Christians KK, Barnes CA, Jariwalla NR, Aldakkak M, Clarke CN, George B, Ritch PS, Riese M, Khan AH, Kulkarni N, Evans J, Erickson BA, Evans DB, Tsai S) Front Oncol 2020;10:460 PMID: 32351886 PMCID: PMC7175033 SCOPUS ID: 2-s2.0-85084010622 05/01/2020 19 Citations

Safety and Efficacy Results of a Phase I, Open-Label Study of Concurrent and Delayed Nivolumab in Combination With nab-Paclitaxel and Carboplatin in Advanced Non-small Cell Lung Cancer. (Goldman JW, Waterhouse DM, George B, O'Dwyer PJ, Bhore R, Banerjee S, Lyons L, Louis CU, Ong TJ, Kelly K) Front Oncol 2019;9:1256 PMID: 31850192 PMCID: PMC6901975 SCOPUS ID: 2-s2.0-85076687298 12/19/2019 11 Citations

Role of Molecular Profiling of Pancreatic Cancer After Neoadjuvant Therapy: Does it Change Practice? (Krepline AN, Bliss L, Geurts J, Akinola I, Christians KK, George B, Ritch PS, Hall WA, Erickson BA, Evans DB, Tsai S) J Gastrointest Surg 2020 Feb;24(2):235-242 PMID: 31745905 SCOPUS ID: 2-s2.0-85076028351 11/21/2019 7 Citations

Management of Acute Cholecystitis during Neoadjuvant Therapy in Patients with Pancreatic Adenocarcinoma. (Jariwalla NR, Khan AH, Dua K, Christians KK, Clarke CN, Aldakkak M, George B, Tutton S, Rilling W, Erickson B, Evans DB, Tsai S) Ann Surg Oncol 2019 Dec;26(13):4515-4521 PMID: 31641946 SCOPUS ID: 2-s2.0-85074492297 10/24/2019 7 Citations

Efficacy and Safety of Trifluridine/Tipiracil Treatment in Patients With Metastatic Gastric Cancer Who Had Undergone Gastrectomy: Subgroup Analyses of a Randomized Clinical Trial. (Ilson DH, Tabernero J, Prokharau A, Arkenau HT, Ghidini M, Fujitani K, Van Cutsem E, Thuss-Patience P, Beretta GD, Mansoor W, Zhavrid E, Alsina M, George B, Catenacci D, McGuigan S, Makris L, Doi T, Shitara K) JAMA Oncol 2020 Jan 01;6(1):e193531 PMID: 31600365 PMCID: PMC6802061 SCOPUS ID: 2-s2.0-85073682722 10/11/2019 19 Citations

Molecular and Genetic Markers in Appendiceal Mucinous Tumors: A Systematic Review. (Stein A, Strong E, Clark Gamblin T, Clarke C, Tsai S, Thomas J, George B, Mogal H) Ann Surg Oncol 2020 Jan;27(1):85-97 PMID: 31583543 SCOPUS ID: 2-s2.0-85074461946 10/05/2019 20 Citations

Survival of patients with borderline resectable pancreatic cancer who received neoadjuvant therapy and surgery. (Barnes CA, Chavez MI, Tsai S, Aldakkak M, George B, Ritch PS, Dua K, Clarke CN, Tolat P, Hagen C, Hall WA, Erickson BA, Evans DB, Christians KK) Surgery 2019 Sep;166(3):277-285 PMID: 31272811 SCOPUS ID: 2-s2.0-85068174272 07/06/2019 42 Citations

Etanercept for Treatment of Taxane-Induced Pneumonitis. (Singavi AK, Ramalingam V, George B) J Oncol Pract 2019 Oct;15(10):556-557 PMID: 31219735 SCOPUS ID: 2-s2.0-85073126372 06/21/2019 3 Citations

Downstaging Locally Advanced Cholangiocarcinoma Pre-Liver Transplantation: A Prospective Pilot Study. (Wong M, Kim J, George B, Eriksen C, Pearson T, Robbins J, Zimmerman MA, Hong JC) J Surg Res 2019 Oct;242:23-30 PMID: 31059945 SCOPUS ID: 2-s2.0-85065040956 05/07/2019 23 Citations

Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers. (Singhi AD, George B, Greenbowe JR, Chung J, Suh J, Maitra A, Klempner SJ, Hendifar A, Milind JM, Golan T, Brand RE, Zureikat AH, Roy S, Schrock AB, Miller VA, Ross JS, Ali SM, Bahary N) Gastroenterology 2019 Jun;156(8):2242-2253.e4 PMID: 30836094 SCOPUS ID: 2-s2.0-85064216307 03/06/2019 214 Citations

Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients. (Pabla S, Conroy JM, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Hagen J, Giamo V, Andreas J, Lenzo FL, Yirong W, Dy GK, Yau E, Early A, Chen H, Bshara W, Madden KG, Shirai K, Dragnev K, Tafe LJ, Marin D, Zhu J, Clarke J, Labriola M, McCall S, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Dressler L, Steciuk M, Binns O, Kasuganti D, Shah N, Ernstoff M, Odunsi K, Kurzrock R, Gardner M, Galluzzi L, Morrison C) J Immunother Cancer 2019 Feb 01;7(1):27 PMID: 30709424 PMCID: PMC6359802 SCOPUS ID: 2-s2.0-85060929943 02/03/2019 61 Citations

Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors. (Conroy JM, Pabla S, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Wang Y, Lenzo FL, Bshara W, Khalil M, Dy GK, Madden KG, Shirai K, Dragnev K, Tafe LJ, Zhu J, Labriola M, Marin D, McCall SJ, Clarke J, George DJ, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, de la Cruz-Merino L, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Kasuganti D, Shah N, Day R, Galluzzi L, Gardner M, Morrison C) J Immunother Cancer 2019 Jan 24;7(1):18 PMID: 30678715 PMCID: PMC6346512 SCOPUS ID: 2-s2.0-85060525068 01/27/2019 68 Citations

Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue. (Shuen AY, Lanni S, Panigrahi GB, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Zhukova N, Alharbi M, Bernstein M, Bowers DC, Carroll S, Cole KA, Constantini S, Crooks B, Dvir R, Farah R, Hijiya N, George B, Laetsch TW, Larouche V, Lindhorst S, Luiten RC, Magimairajan V, Mason G, Mason W, Mordechai O, Mushtaq N, Nicholas G, Oren M, Palma L, Pedroza LA, Ramdas J, Samuel D, Wolfe Schneider K, Seeley A, Semotiuk K, Shamvil A, Sumerauer D, Toledano H, Tomboc P, Wierman M, Van Damme A, Lee YY, Zapotocky M, Bouffet E, Durno C, Aronson M, Gallinger S, Foulkes WD, Malkin D, Tabori U, Pearson CE) J Clin Oncol 2019 Feb 20;37(6):461-470 PMID: 30608896 SCOPUS ID: 2-s2.0-85061585456 01/05/2019 23 Citations

Immunogenomic Landscape Contributes to Hyperprogressive Disease after Anti-PD-1 Immunotherapy for Cancer. (Xiong D, Wang Y, Singavi AK, Mackinnon AC, George B, You M) iScience 2018 Nov 30;9:258-277 PMID: 30439581 PMCID: PMC6234258 SCOPUS ID: 2-s2.0-85064993721 11/16/2018 70 Citations

Importance of Normalization of CA19-9 Levels Following Neoadjuvant Therapy in Patients With Localized Pancreatic Cancer. (Tsai S, George B, Wittmann D, Ritch PS, Krepline AN, Aldakkak M, Barnes CA, Christians KK, Dua K, Griffin M, Hagen C, Hall WA, Erickson BA, Evans DB) Ann Surg 2020 Apr;271(4):740-747 PMID: 30312198 SCOPUS ID: 2-s2.0-85082099572 10/13/2018 123 Citations

A Phase II Clinical Trial of Molecular Profiled Neoadjuvant Therapy for Localized Pancreatic Ductal Adenocarcinoma. (Tsai S, Christians KK, George B, Ritch PS, Dua K, Khan A, Mackinnon AC, Tolat P, Ahmad SA, Hall WA, Erickson BA, Evans DB) Ann Surg 2018 Oct;268(4):610-619 PMID: 30080723 SCOPUS ID: 2-s2.0-85067054610 08/07/2018 56 Citations

Locally advanced pancreas cancer: Staging and goals of therapy. (Chatzizacharias NA, Tsai S, Griffin M, Tolat P, Ritch P, George B, Barnes C, Aldakkak M, Khan AH, Hall W, Erickson B, Evans DB, Christians KK) Surgery 2018 May;163(5):1053-1062 PMID: 29331400 SCOPUS ID: 2-s2.0-85040254084 01/15/2018 46 Citations

Comprehensive Analysis of Hypermutation in Human Cancer. (Campbell BB, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, Bowers DC, Laetsch TW, Dunn GP, Johanns TM, Grimmer MR, Smirnov IV, Larouche V, Samuel D, Bronsema A, Osborn M, Stearns D, Raman P, Cole KA, Storm PB, Yalon M, Opocher E, Mason G, Thomas GA, Sabel M, George B, Ziegler DS, Lindhorst S, Issai VM, Constantini S, Toledano H, Elhasid R, Farah R, Dvir R, Dirks P, Huang A, Galati MA, Chung J, Ramaswamy V, Irwin MS, Aronson M, Durno C, Taylor MD, Rechavi G, Maris JM, Bouffet E, Hawkins C, Costello JF, Meyn MS, Pursell ZF, Malkin D, Tabori U, Shlien A) Cell 2017 Nov 16;171(5):1042-1056.e10 PMID: 29056344 PMCID: PMC5849393 SCOPUS ID: 2-s2.0-85031810803 10/24/2017 526 Citations

Should functional renal scans be obtained prior to upper abdominal IMRT for pancreatic cancer? (Blitzer GC, Hall WA, Tsai S, Aldakkak M, Hellman RS, Evans DB, Christians KK, George B, Ritch PS, Erickson BA) Pract Radiat Oncol 2017;7(6):e449-e455 PMID: 28886941 SCOPUS ID: 2-s2.0-85028763165 09/10/2017

Is Adjuvant Therapy Necessary for All Patients with Localized Pancreatic Cancer Who Have Received Neoadjuvant Therapy? (Barnes CA, Krepline AN, Aldakkak M, Clarke CN, Christians KK, Khan AH, Hunt BC, Ritch PS, George B, Hall WA, Erickson BA, Evans DB, Tsai S) J Gastrointest Surg 2017 Nov;21(11):1793-1803 PMID: 28849366 SCOPUS ID: 2-s2.0-85028529403 08/30/2017 24 Citations

Poor Glycemic Control Is Associated with Failure to Complete Neoadjuvant Therapy and Surgery in Patients with Localized Pancreatic Cancer. (Rajamanickam ES, Christians KK, Aldakkak M, Krepline AN, Ritch PS, George B, Erickson BA, Foley WD, Aburajab M, Evans DB, Tsai S) J Gastrointest Surg 2017 Mar;21(3):496-505 PMID: 27896658 SCOPUS ID: 2-s2.0-84997795492 11/30/2016 7 Citations

Multimodality Therapy in Patients With Borderline Resectable or Locally Advanced Pancreatic Cancer: Importance of Locoregional Therapies for a Systemic Disease. (Tsai S, Christians KK, Ritch PS, George B, Khan AH, Erickson B, Evans DB) J Oncol Pract 2016 Oct;12(10):915-923 PMID: 27858562 SCOPUS ID: 2-s2.0-84991252464 11/20/2016 18 Citations

Venous thromboembolism prophylaxis during neoadjuvant therapy for resectable and borderline resectable pancreatic cancer-Is it indicated? (Krepline AN, Christians KK, George B, Ritch PS, Erickson BA, Tolat P, Evans DB, Tsai S) J Surg Oncol 2016 Oct;114(5):581-586 PMID: 27760280 SCOPUS ID: 2-s2.0-84992111849 10/22/2016 21 Citations

High-Grade Neuroendocrine Colorectal Carcinomas: A Retrospective Study of 100 Patients. (Conte B, George B, Overman M, Estrella J, Jiang ZQ, Mehrvarz Sarshekeh A, Ferrarotto R, Hoff PM, Rashid A, Yao JC, Kopetz S, Dasari A) Clin Colorectal Cancer 2016 Jun;15(2):e1-7 PMID: 26810202 PMCID: PMC4885752 SCOPUS ID: 2-s2.0-84955278739 01/27/2016 38 Citations

Survival of patients with resectable pancreatic cancer who received neoadjuvant therapy. (Christians KK, Heimler JW, George B, Ritch PS, Erickson BA, Johnston F, Tolat PP, Foley WD, Evans DB, Tsai S) Surgery 2016 Mar;159(3):893-900 PMID: 26602840 SCOPUS ID: 2-s2.0-84950987094 11/26/2015 102 Citations

Comparative Effectiveness of Hepatic Artery Based Therapies for Unresectable Colorectal Liver Metastases: A Meta-Analysis. (Zacharias AJ, Jayakrishnan TT, Rajeev R, Rilling WS, Thomas JP, George B, Johnston FM, Gamblin TC, Turaga KK) PLoS One 2015;10(10):e0139940 PMID: 26448327 PMCID: PMC4598149 SCOPUS ID: 2-s2.0-84948706797 10/09/2015 41 Citations

Neoadjuvant therapy for localized pancreatic cancer: guiding principles. (Fathi A, Christians KK, George B, Ritch PS, Erickson BA, Tolat P, Johnston FM, Evans DB, Tsai S) J Gastrointest Oncol 2015 Aug;6(4):418-29 PMID: 26261728 PMCID: PMC4502155 SCOPUS ID: 2-s2.0-84995784225 08/12/2015 49 Citations

Pre-treatment carbohydrate antigen 19-9 does not predict the response to neoadjuvant therapy in patients with localized pancreatic cancer. (Aldakkak M, Christians KK, Krepline AN, George B, Ritch PS, Erickson BA, Johnston FM, Evans DB, Tsai S) HPB (Oxford) 2015 Oct;17(10):942-52 PMID: 26255895 PMCID: PMC4571763 SCOPUS ID: 2-s2.0-84941878704 08/11/2015 52 Citations

Use of neoadjuvant therapy in patients 75 years of age and older with pancreatic cancer. (Miura JT, Krepline AN, George B, Ritch PS, Erickson BA, Johnston FM, Oshima K, Christians KK, Evans DB, Tsai S) Surgery 2015 Dec;158(6):1545-55 PMID: 26243342 SCOPUS ID: 2-s2.0-84947023760 08/06/2015 28 Citations

Non-metastatic Pancreatic Cancer: Resectable, Borderline Resectable, and Locally Advanced-Definitions of Increasing Importance for the Optimal Delivery of Multimodality Therapy. (Evans DB, George B, Tsai S) Ann Surg Oncol 2015 Oct;22(11):3409-13 PMID: 26122369 SCOPUS ID: 2-s2.0-84941417302 07/01/2015 70 Citations

An Unusual Combination: KRAS and BRAF Co-mutated Metastatic Colorectal Cancer. (Epperla N, George B) J Gastrointest Cancer 2016 Jun;47(2):206-9 PMID: 26018827 SCOPUS ID: 2-s2.0-84930154531 05/29/2015

Tumor profiling of gastric and esophageal carcinoma reveal different treatment options. (Miura JT, Xiu J, Thomas J, George B, Carron BR, Tsai S, Johnston FM, Turaga KK, Gamblin TC) Cancer Biol Ther 2015;16(5):764-9 PMID: 25778705 PMCID: PMC4622996 SCOPUS ID: 2-s2.0-84943767513 03/18/2015 19 Citations

Chemotherapy for Surgically Resected Intrahepatic Cholangiocarcinoma. (Miura JT, Johnston FM, Tsai S, George B, Thomas J, Eastwood D, Banerjee A, Christians KK, Turaga KK, Pawlik TM, Clark Gamblin T) Ann Surg Oncol 2015 Oct;22(11):3716-23 PMID: 25777092 SCOPUS ID: 2-s2.0-84941418828 03/18/2015 80 Citations

Acute Onset of Acrokeratosis Paraneoplastica (Bazex Syndrome). (Humphrey SR, Hussain AS, Chandran R, Wilson B, George B) JAMA Dermatol 2015 Jun;151(6):677-8 PMID: 25760248 SCOPUS ID: 2-s2.0-84931096695 03/12/2015 8 Citations

Neoadjuvant chemoradiation with IMRT in resectable and borderline resectable pancreatic cancer. (Kharofa J, Tsai S, Kelly T, Wood C, George B, Ritch P, Wiebe L, Christians K, Evans DB, Erickson B) Radiother Oncol 2014 Oct;113(1):41-6 PMID: 25443499 PMCID: PMC4530020 SCOPUS ID: 2-s2.0-84922745297 12/03/2014 43 Citations

Patency rates of portal vein/superior mesenteric vein reconstruction after pancreatectomy for pancreatic cancer. (Krepline AN, Christians KK, Duelge K, Mahmoud A, Ritch P, George B, Erickson BA, Foley WD, Quebbeman EJ, Turaga KK, Johnston FM, Gamblin TC, Evans DB, Tsai S) J Gastrointest Surg 2014 Nov;18(11):2016-25 PMID: 25227638 SCOPUS ID: 2-s2.0-84920138622 09/18/2014 39 Citations

Diagnostic laparoscopy should be performed before definitive resection for pancreatic cancer: a financial argument. (Jayakrishnan TT, Nadeem H, Groeschl RT, George B, Thomas JP, Ritch PS, Christians KK, Tsai S, Evans DB, Pappas SG, Gamblin TC, Turaga KK) HPB (Oxford) 2015 Feb;17(2):131-9 PMID: 25123702 PMCID: PMC4299387 SCOPUS ID: 2-s2.0-84920841239 08/16/2014 17 Citations

Molecular profiling in gastric cancer: examining potential targets for chemotherapy. (Miura JT, Johnston FM, Thomas J, George B, Eastwood D, Tsai S, Christians KK, Turaga KK, Gamblin TC) J Surg Oncol 2014 Sep;110(3):302-6 PMID: 24844210 SCOPUS ID: 2-s2.0-84905367494 05/23/2014 9 Citations

Arterial resection at the time of pancreatectomy for cancer. (Christians KK, Pilgrim CH, Tsai S, Ritch P, George B, Erickson B, Tolat P, Evans DB) Surgery 2014 May;155(5):919-26 PMID: 24787115 SCOPUS ID: 2-s2.0-84899659181 05/03/2014 82 Citations

Systematic review of outcomes of patients undergoing resection for colorectal liver metastases in the setting of extra hepatic disease. (Hwang M, Jayakrishnan TT, Green DE, George B, Thomas JP, Groeschl RT, Erickson B, Pappas SG, Gamblin TC, Turaga KK) Eur J Cancer 2014 Jul;50(10):1747-1757 PMID: 24767470 SCOPUS ID: 2-s2.0-84901752316 04/29/2014 74 Citations

Management of acute cholecystitis in cancer patients: a comparative effectiveness approach. (Jayakrishnan TT, Groeschl RT, George B, Thomas JP, Pappas S, Gamblin TC, Turaga KK) Surg Endosc 2014 May;28(5):1505-14 PMID: 24687416 SCOPUS ID: 2-s2.0-84900328041 04/02/2014 7 Citations

Neoadjuvant FOLFIRINOX for borderline resectable pancreas cancer: a new treatment paradigm? (Christians KK, Tsai S, Mahmoud A, Ritch P, Thomas JP, Wiebe L, Kelly T, Erickson B, Wang H, Evans DB, George B) Oncologist 2014 Mar;19(3):266-74 PMID: 24569947 PMCID: PMC3958454 SCOPUS ID: 2-s2.0-84896486447 02/27/2014 166 Citations

Review of the impact of antineoplastic therapies on the risk for cholelithiasis and acute cholecystitis. (Jayakrishnan TT, Groeschl RT, George B, Thomas JP, Clark Gamblin T, Turaga KK) Ann Surg Oncol 2014 Jan;21(1):240-7 PMID: 24114054 SCOPUS ID: 2-s2.0-84891708354 10/12/2013 15 Citations

Ciliated hepatic cyst leading to squamous cell carcinoma of the liver - A case report and review of the literature. (Wilson JM, Groeschl R, George B, Turaga KK, Patel PJ, Saeian K, Gamblin TC) Int J Surg Case Rep 2013;4(11):972-5 PMID: 24055921 PMCID: PMC3825928 SCOPUS ID: 2-s2.0-84884680909 09/24/2013 25 Citations

Survival benefit associated with surgical oophorectomy in patients with colorectal cancer metastatic to the ovary. (Garrett CR, George B, Viswanathan C, Bhadkamkar NA, Wen S, Baladandayuthapani V, You YN, Kopetz ES, Overman MJ, Kee BK, Eng C) Clin Colorectal Cancer 2012 Sep;11(3):191-4 PMID: 22280844 SCOPUS ID: 2-s2.0-84865517332 01/28/2012 23 Citations

Predictive and prognostic markers in colorectal cancer. (George B, Kopetz S) Curr Oncol Rep 2011 Jun;13(3):206-15 PMID: 21373987 SCOPUS ID: 2-s2.0-79955900130 03/05/2011 42 Citations

Posterior reversible encephalopathy syndrome as a consequence of high dose steroid administration after autologous PBSCT. (Sukumaran S, George B, Nair HP, Drobyski WR) Bone Marrow Transplant 2010 Apr;45(4):779-80 PMID: 19684634 SCOPUS ID: 2-s2.0-77950629302 08/18/2009 9 Citations

Complete and durable response of choroid metastasis from non-small cell lung cancer with systemic bevacizumab and chemotherapy. (George B, Wirostko WJ, Connor TB, Choong NW) J Thorac Oncol 2009 May;4(5):661-2 PMID: 19395911 SCOPUS ID: 2-s2.0-67651159238 04/28/2009 35 Citations

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Ben George MD

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Publications (82)