Medical College of Wisconsin
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Gyujoon Hwang PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Psychiatry and Behavioral Medicine
Program: General Research and Clinical Trials

Member of the Wisconsin Institute of NeuroScience (WINS)

Research Areas of Interest

  • Machine Learning
  • Neuroimaging

    • Publications (26)

  • Relationship between MRI brain-age heterogeneity, cognition, genetics and Alzheimer's disease neuropathology. (Antoniades M, Srinivasan D, Wen J, Erus G, Abdulkadir A, Mamourian E, Melhem R, Hwang G, Cui Y, Govindarajan ST, Chen AA, Zhou Z, Yang Z, Chen J, Pomponio R, Sotardi S, An Y, Bilgel M, LaMontagne P, Singh A, Benzinger T, Beason-Held L, Marcus DS, Yaffe K, Launer L, Morris JC, Tosun D, Ferrucci L, Bryan RN, Resnick SM, Habes M, Wolk D, Fan Y, Nasrallah IM, Shou H, Davatzikos C) EBioMedicine 2024 Nov;109:105399 PMID: 39437659 PMCID: PMC11536027 SCOPUS ID: 2-s2.0-85206914012 10/23/2024    
  • Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer's disease continuum. (Wen J, Yang Z, Nasrallah IM, Cui Y, Erus G, Srinivasan D, Abdulkadir A, Mamourian E, Hwang G, Singh A, Bergman M, Bao J, Varol E, Zhou Z, Boquet-Pujadas A, Chen J, Toga AW, Saykin AJ, Hohman TJ, Thompson PM, Villeneuve S, Gollub R, Sotiras A, Wittfeld K, Grabe HJ, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Benzinger TL, Heckbert SR, Austin TR, Launer LJ, Espeland M, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Resnick SM, Ferrucci L, Fan Y, Habes M, Wolk D, Shen L, Shou H, Davatzikos C) Transl Psychiatry 2024 Oct 05;14(1):420 PMID: 39368996 PMCID: PMC11455841 SCOPUS ID: 2-s2.0-85205758659 10/06/2024    
  • Dimensional Neuroimaging Endophenotypes: Neurobiological Representations of Disease Heterogeneity Through Machine Learning. (Wen J, Antoniades M, Yang Z, Hwang G, Skampardoni I, Wang R, Davatzikos C) Biol Psychiatry 2024 Oct 01;96(7):564-584 PMID: 38718880 PMCID: PMC11374488 SCOPUS ID: 2-s2.0-85195576462 05/09/2024       2 Citations
  • The genetic architecture of multimodal human brain age. (Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C) Nat Commun 2024 Mar 23;15(1):2604 PMID: 38521789 PMCID: PMC10960798 SCOPUS ID: 2-s2.0-85188443845 03/24/2024       8 Citations
  • Neuropsychological correlates of early grief in bereaved older adults. (Hoffmann BM, Blair NP, McAuliffe TL, Hwang G, Larson E, Claesges SA, Webber A, Reynolds CF 3rd, Goveas JS) Int Psychogeriatr 2024 Mar 11:1-6 PMID: 38462965 PMCID: PMC11387951 SCOPUS ID: 2-s2.0-85187712212 03/11/2024    
  • Genetic and Clinical Correlates of AI-Based Brain Aging Patterns in Cognitively Unimpaired Individuals. (Skampardoni I, Nasrallah IM, Abdulkadir A, Wen J, Melhem R, Mamourian E, Erus G, Doshi J, Singh A, Yang Z, Cui Y, Hwang G, Ren Z, Pomponio R, Srinivasan D, Govindarajan ST, Parmpi P, Wittfeld K, Grabe HJ, Bülow R, Frenzel S, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Heckbert SR, Austin TR, Launer LJ, Sotiras A, Espeland MA, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Yaffe K, Völzke H, Ferrucci L, Benzinger TLS, Ezzati A, Shinohara RT, Fan Y, Resnick SM, Habes M, Wolk D, Shou H, Nikita K, Davatzikos C) JAMA Psychiatry 2024 May 01;81(5):456-467 PMID: 38353984 PMCID: PMC10867779 SCOPUS ID: 2-s2.0-85185283495 02/14/2024       3 Citations
  • Dimensional Neuroimaging Endophenotypes: Neurobiological Representations of Disease Heterogeneity Through Machine Learning. (Wen J, Antoniades M, Yang Z, Hwang G, Skampardoni I, Wang R, Davatzikos C) ArXiv 2024 Jan 17 PMID: 38313197 PMCID: PMC10836087 02/05/2024    
  • Genomic loci influence patterns of structural covariance in the human brain. (Wen J, Nasrallah IM, Abdulkadir A, Satterthwaite TD, Yang Z, Erus G, Robert-Fitzgerald T, Singh A, Sotiras A, Boquet-Pujadas A, Mamourian E, Doshi J, Cui Y, Srinivasan D, Skampardoni I, Chen J, Hwang G, Bergman M, Bao J, Veturi Y, Zhou Z, Yang S, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Gur RC, Gur RE, Koutsouleris N, Wolf DH, Saykin AJ, Ritchie MD, Shen L, Thompson PM, Colliot O, Wittfeld K, Grabe HJ, Tosun D, Bilgel M, An Y, Marcus DS, LaMontagne P, Heckbert SR, Austin TR, Launer LJ, Espeland M, Masters CL, Maruff P, Fripp J, Johnson SC, Morris JC, Albert MS, Bryan RN, Resnick SM, Fan Y, Habes M, Wolk D, Shou H, Davatzikos C) Proc Natl Acad Sci U S A 2023 Dec 26;120(52):e2300842120 PMID: 38127979 PMCID: PMC10756284 SCOPUS ID: 2-s2.0-85181179290 12/21/2023       8 Citations
  • Tau-neurodegeneration mismatch reveals vulnerability and resilience to comorbidities in Alzheimer's continuum. (Lyu X, Duong MT, Xie L, de Flores R, Richardson H, Hwang G, Wisse LEM, DiCalogero M, McMillan CT, Robinson JL, Xie SX, Lee EB, Irwin DJ, Dickerson BC, Davatzikos C, Nasrallah IM, Yushkevich PA, Wolk DA, Das SR, Alzheimer's Disease Neuroimaging Initiative) Alzheimers Dement 2024 Mar;20(3):1586-1600 PMID: 38050662 PMCID: PMC10984442 SCOPUS ID: 2-s2.0-85161816922 12/05/2023       4 Citations
  • Nine Neuroimaging-AI Endophenotypes Unravel Disease Heterogeneity and Partial Overlap across Four Brain Disorders: A Dimensional Neuroanatomical Representation. (Wen J, Skampardoni I, Tian YE, Yang Z, Cui Y, Erus G, Hwang G, Varol E, Boquet-Pujadas A, Chand GB, Nasrallah I, Satterthwaite T, Shou H, Shen L, Toga AW, Zalesky A, Davatzikos C) medRxiv 2024 Sep 25 PMID: 37662256 PMCID: PMC10473785 09/04/2023    
  • The Genetic Architecture of Multimodal Human Brain Age. (Wen J, Zhao B, Yang Z, Erus G, Skampardoni I, Mamourian E, Cui Y, Hwang G, Bao J, Boquet-Pujadas A, Zhou Z, Veturi Y, Ritchie MD, Shou H, Thompson PM, Shen L, Toga AW, Davatzikos C) bioRxiv 2023 Sep 30 PMID: 37333190 PMCID: PMC10274645 06/19/2023    
  • Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium. (Dwyer DB, Chand GB, Pigoni A, Khuntia A, Wen J, Antoniades M, Hwang G, Erus G, Doshi J, Srinivasan D, Varol E, Kahn RS, Schnack HG, Meisenzahl E, Wood SJ, Zhuo C, Sotiras A, Shinohara RT, Shou H, Fan Y, Schaulfelberger M, Rosa P, Lalousis PA, Upthegrove R, Kaczkurkin AN, Moore TM, Nelson B, Gur RE, Gur RC, Ritchie MD, Satterthwaite TD, Murray RM, Di Forti M, Ciufolini S, Zanetti MV, Wolf DH, Pantelis C, Crespo-Facorro B, Busatto GF, Davatzikos C, Koutsouleris N, Dazzan P) Mol Psychiatry 2023 May;28(5):2008-2017 PMID: 37147389 PMCID: PMC10575777 SCOPUS ID: 2-s2.0-85158129069 05/06/2023       8 Citations
  • Assessment of Neuroanatomical Endophenotypes of Autism Spectrum Disorder and Association With Characteristics of Individuals With Schizophrenia and the General Population. (Hwang G, Wen J, Sotardi S, Brodkin ES, Chand GB, Dwyer DB, Erus G, Doshi J, Singhal P, Srinivasan D, Varol E, Sotiras A, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Shou H, Fan Y, Di Martino A, Koutsouleris N, Gur RE, Gur RC, Satterthwaite TD, Wolf DH, Davatzikos C) JAMA Psychiatry 2023 May 01;80(5):498-507 PMID: 37017948 PMCID: PMC10157419 SCOPUS ID: 2-s2.0-85159060372 04/06/2023       7 Citations
  • Subtyping Brain Diseases from Imaging Data (Wen J, Varol E, Yang Z, Hwang G, Dwyer D, Kazerooni AF, Lalousis PA, Davatzikos C) Neuromethods 2023;197:491-510 SCOPUS ID: 2-s2.0-85172029608 01/01/2023       4 Citations
  • Autism Spectrum Disorder: Time to Notice the Individuals More Than the Group. (Hwang G) Biol Psychiatry 2022 Oct 15;92(8):606-608 PMID: 36137703 SCOPUS ID: 2-s2.0-85138365786 09/23/2022       3 Citations
  • Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes. (Lalousis PA, Schmaal L, Wood SJ, Reniers RLEP, Barnes NM, Chisholm K, Griffiths SL, Stainton A, Wen J, Hwang G, Davatzikos C, Wenzel J, Kambeitz-Ilankovic L, Andreou C, Bonivento C, Dannlowski U, Ferro A, Lichtenstein T, Riecher-Rössler A, Romer G, Rosen M, Bertolino A, Borgwardt S, Brambilla P, Kambeitz J, Lencer R, Pantelis C, Ruhrmann S, Salokangas RKR, Schultze-Lutter F, Schmidt A, Meisenzahl E, Koutsouleris N, Dwyer D, Upthegrove R, PRONIA Consortium) Biol Psychiatry 2022 Oct 01;92(7):552-562 PMID: 35717212 PMCID: PMC10128104 SCOPUS ID: 2-s2.0-85132873503 06/19/2022       17 Citations
  • Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning. (Hwang G, Abdulkadir A, Erus G, Habes M, Pomponio R, Shou H, Doshi J, Mamourian E, Rashid T, Bilgel M, Fan Y, Sotiras A, Srinivasan D, Morris JC, Albert MS, Bryan NR, Resnick SM, Nasrallah IM, Davatzikos C, Wolk DA, from the iSTAGING consortium, ADNI) Brain Commun 2022;4(3):fcac117 PMID: 35611306 PMCID: PMC9123890 SCOPUS ID: 2-s2.0-85134903323 05/26/2022       10 Citations
  • Schizophrenia Imaging Signatures and Their Associations With Cognition, Psychopathology, and Genetics in the General Population. (Chand GB, Singhal P, Dwyer DB, Wen J, Erus G, Doshi J, Srinivasan D, Mamourian E, Varol E, Sotiras A, Hwang G, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Shou H, Fan Y, Koutsouleris N, Kaczkurkin AN, Moore TM, Verma A, Calkins ME, Gur RE, Gur RC, Ritchie MD, Satterthwaite TD, Wolf DH, Davatzikos C) Am J Psychiatry 2022 Sep;179(9):650-660 PMID: 35410495 PMCID: PMC9444886 SCOPUS ID: 2-s2.0-85137078437 04/13/2022       22 Citations
  • Network, clinical and sociodemographic features of cognitive phenotypes in temporal lobe epilepsy. (Hermann B, Conant LL, Cook CJ, Hwang G, Garcia-Ramos C, Dabbs K, Nair VA, Mathis J, Bonet CNR, Allen L, Almane DN, Arkush K, Birn R, DeYoe EA, Felton E, Maganti R, Nencka A, Raghavan M, Shah U, Sosa VN, Struck AF, Ustine C, Reyes A, Kaestner E, McDonald C, Prabhakaran V, Binder JR, Meyerand ME) Neuroimage Clin 2020;27:102341 PMID: 32707534 PMCID: PMC7381697 SCOPUS ID: 2-s2.0-85088252788 07/25/2020       52 Citations
  • Neuroticism in temporal lobe epilepsy is associated with altered limbic-frontal lobe resting-state functional connectivity. (Rivera Bonet CN, Hwang G, Hermann B, Struck AF, J Cook C, A Nair V, Mathis J, Allen L, Almane DN, Arkush K, Birn R, Conant LL, DeYoe EA, Felton E, Maganti R, Nencka A, Raghavan M, Shah U, Sosa VN, Ustine C, Prabhakaran V, Binder JR, Meyerand ME) Epilepsy Behav 2020 Sep;110:107172 PMID: 32554180 PMCID: PMC7483612 SCOPUS ID: 2-s2.0-85086476142 06/20/2020       9 Citations
  • Multi-Channel Deep Neural Network for Temporal Lobe Epilepsy Classification Using Multimodal Mri Data (Torres-Velazquez M, Hwang G, Cook CJ, Hermann B, Prabhakaran V, Meyerand ME, McMillan AB) ISBI Workshops 2020 - International Symposium on Biomedical Imaging Workshops, Proceedings April 2020 SCOPUS ID: 2-s2.0-85090407937 04/01/2020       7 Citations
  • Brain aging in temporal lobe epilepsy: Chronological, structural, and functional. (Hwang G, Hermann B, Nair VA, Conant LL, Dabbs K, Mathis J, Cook CJ, Rivera-Bonet CN, Mohanty R, Zhao G, Almane DN, Nencka A, Felton E, Struck AF, Birn R, Maganti R, Humphries CJ, Raghavan M, DeYoe EA, Bendlin BB, Prabhakaran V, Binder JR, Meyerand ME) Neuroimage Clin 2020;25:102183 PMID: 32058319 PMCID: PMC7016276 SCOPUS ID: 2-s2.0-85079141146 02/15/2020       30 Citations
  • Neuroanatomical correlates of personality traits in temporal lobe epilepsy: Findings from the Epilepsy Connectome Project. (Rivera Bonet CN, Hermann B, Cook CJ, Hwang G, Dabbs K, Nair V, Forseth C, Mathis J, Allen L, Almane DN, Arkush K, Birn R, Conant LL, DeYoe EA, Felton E, Humphries CJ, Kraegel P, Maganti R, Nencka A, Nwoke O, Raghavan M, Rozman M, Shah U, Sosa VN, Struck AF, Tellapragada N, Ustine C, Ward BD, Prabhakaran V, Binder JR, Meyerand ME) Epilepsy Behav 2019 Sep;98(Pt A):220-227 PMID: 31387000 PMCID: PMC6732015 SCOPUS ID: 2-s2.0-85071832268 08/07/2019       16 Citations
  • Cognitive slowing and its underlying neurobiology in temporal lobe epilepsy. (Hwang G, Dabbs K, Conant L, Nair VA, Mathis J, Almane DN, Nencka A, Birn R, Humphries C, Raghavan M, DeYoe EA, Struck AF, Maganti R, Binder JR, Meyerand E, Prabhakaran V, Hermann B) Cortex 2019 Aug;117:41-52 PMID: 30927560 PMCID: PMC6650302 SCOPUS ID: 2-s2.0-85063324806 03/31/2019       41 Citations
  • Using Low-Frequency Oscillations to Detect Temporal Lobe Epilepsy with Machine Learning. (Hwang G, Nair VA, Mathis J, Cook CJ, Mohanty R, Zhao G, Tellapragada N, Ustine C, Nwoke OO, Rivera-Bonet C, Rozman M, Allen L, Forseth C, Almane DN, Kraegel P, Nencka A, Felton E, Struck AF, Birn R, Maganti R, Conant LL, Humphries CJ, Hermann B, Raghavan M, DeYoe EA, Binder JR, Meyerand E, Prabhakaran V) Brain Connect 2019 Mar;9(2):184-193 PMID: 30803273 PMCID: PMC6484357 SCOPUS ID: 2-s2.0-85063084464 02/26/2019       17 Citations
  • Effective Connectivity Within the Default Mode Network in Left Temporal Lobe Epilepsy: Findings from the Epilepsy Connectome Project. (Cook CJ, Hwang G, Mathis J, Nair VA, Conant LL, Allen L, Almane DN, Birn R, DeYoe EA, Felton E, Forseth C, Humphries CJ, Kraegel P, Nencka A, Nwoke O, Raghavan M, Rivera-Bonet C, Rozman M, Tellapragada N, Ustine C, Ward BD, Struck A, Maganti R, Hermann B, Prabhakaran V, Binder JR, Meyerand ME) Brain Connect 2019 Mar;9(2):174-183 PMID: 30398367 PMCID: PMC6444922 SCOPUS ID: 2-s2.0-85063100708 11/07/2018       30 Citations
    • Last update: 11/02/2024