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Ashraf El-Meanawy MD, PhD

Ashraf El-Meanawy MD, PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Nephrology
Program: Administration

Member of the Cardiovascular Center


Research Experience

  • Biology
  • Embryonic Development
  • Embryonic and Fetal Development
  • Genetics
  • Molecular Biology
  • Clinical Expertise

  • Hemodiafiltration
  • Hemodialysis, Home
  • Internal Medicine
  • Peritoneal Dialysis
  • Renal Dialysis
  • Renal Replacement Therapy
  • Sorption Detoxification
  • Publications

  • Mechanotransduction signaling in podocytes from fluid flow shear stress. (Srivastava T, Dai H, Heruth DP, Alon US, Garola RE, Zhou J, Duncan RS, El-Meanawy A, McCarthy ET, Sharma R, Johnson ML, Savin VJ, Sharma M) Am J Physiol Renal Physiol 2018 01 01;314(1):F22-F34 PMID: 28877882 PMCID: PMC5866353 09/08/2017    
  • Role of biomechanical forces in hyperfiltration-mediated glomerular injury in congenital anomalies of the kidney and urinary tract. (Srivastava T, Thiagarajan G, Alon US, Sharma R, El-Meanawy A, McCarthy ET, Savin VJ, Sharma M) Nephrol Dial Transplant 2017 May 01;32(5):759-765 PMID: 28339567 PMCID: PMC6075083 03/25/2017       4 Citations
  • Mechanisms of BK virus infection of renal cells and therapeutic implications. (Mbianda C, El-Meanawy A, Sorokin A) J Clin Virol 2015 Oct;71:59-62 PMID: 26295751 PMCID: PMC4572911 08/22/2015       5 Citations
  • Cyclooxygenase-2, prostaglandin E2, and prostanoid receptor EP2 in fluid flow shear stress-mediated injury in the solitary kidney. (Srivastava T, Alon US, Cudmore PA, Tarakji B, Kats A, Garola RE, Duncan RS, McCarthy ET, Sharma R, Johnson ML, Bonewald LF, El-Meanawy A, Savin VJ, Sharma M) Am J Physiol Renal Physiol 2014 Dec 15;307(12):F1323-33 PMID: 25234310 09/23/2014       12 Citations
  • Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis. (Khan S, Abu Jawdeh BG, Goel M, Schilling WP, Parker MD, Puchowicz MA, Yadav SP, Harris RC, El-Meanawy A, Hoshi M, Shinlapawittayatorn K, DeschĂȘnes I, Ficker E, Schelling JR) J Clin Invest 2014 Mar;124(3):1057-68 PMID: 24531551 PMCID: PMC3934167 02/18/2014       12 Citations
  • Fluid flow shear stress upregulates prostanoid receptor EP2 but not EP4 in murine podocytes. (Srivastava T, McCarthy ET, Sharma R, Kats A, Carlton CG, Alon US, Cudmore PA, El-Meanawy A, Sharma M) Prostaglandins Other Lipid Mediat 2013 Jul-Aug;104-105:49-57 PMID: 23262148 12/25/2012       12 Citations
  • Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes. (El-Meanawy A, Schelling JR, Iyengar SK, Hayden P, Barathan S, Goddard K, Pozuelo F, Elashi E, Nair V, Kretzler M, Sedor JR) BMC Nephrol 2012 Jul 19;13:61 PMID: 22813067 PMCID: PMC3502501 07/21/2012       5 Citations
  • Prematurity in mice leads to reduction in nephron number, hypertension, and proteinuria. (Stelloh C, Allen KP, Mattson DL, Lerch-Gaggl A, Reddy S, El-Meanawy A) Transl Res 2012 Feb;159(2):80-9 PMID: 22243792 PMCID: PMC3896045 01/17/2012       31 Citations
  • Short-term exposure to tobacco toxins alters expression of multiple proliferation gene markers in primary human bronchial epithelial cell cultures. (Chaudhry IS, El-Meanawy A, Khiyami A, Tomashefski JF Jr, Machekano RN, Kass L) J Oncol 2011;2011:208563 PMID: 21776270 PMCID: PMC3137990 07/22/2011    
  • Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient. (Sujeet K, Vasudev B, Desai P, Bellizzi J, Novoa-Takara L, He C, El-Meanawy A) Transpl Infect Dis 2011 Apr;13(2):174-7 PMID: 20946204 10/16/2010       16 Citations
  • Recombinant Schistosoma mansoni 3-hydroxymethylglutaryl-coenzyme-A reductase has different inhibitor kinetics compared to the mammalian host enzyme. (El-Meanawy A, Hammd H, Chen GZ, Rottman F, Bennett JL) Trop Gastroenterol 2005 Jul-Sep;26(3):132-5 PMID: 16512462 03/04/2006    
  • The African American Study of Kidney Disease: do these results indicate that 140/90 mm hg is good enough? (Rahman M, El-Meanawy A, Romanello J) Curr Hypertens Rep 2005 Oct;7(5):363-6 PMID: 16157080 09/15/2005       2 Citations
  • Renal phenotype is exacerbated in Os and lpr double mutant mice. (Jarad G, Lakhe-Reddy S, Blatnik J, Koepke M, Khan S, El-Meanawy MA, O'Connor AS, Sedor JR, Schelling JR) Kidney Int 2004 Sep;66(3):1029-35 PMID: 15327396 08/26/2004       4 Citations
  • A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus. (Srichai MB, Konieczkowski M, Padiyar A, Konieczkowski DJ, Mukherjee A, Hayden PS, Kamat S, El-Meanawy MA, Khan S, Mundel P, Lee SB, Bruggeman LA, Schelling JR, Sedor JR) J Biol Chem 2004 Apr 02;279(14):14398-408 PMID: 14736876 01/23/2004       63 Citations
  • Serial analysis of gene expression. (el-Meanawy MA, Barathan S, Hayden PS, Iyengar SK, Schelling JR, Sedor JR) Methods Mol Med 2003;86:257-74 PMID: 12886774 07/31/2003       5 Citations
  • DNA expression analysis: serial analysis of gene expression, microarrays and kidney disease. (Hayden PS, El-Meanawy A, Schelling JR, Sedor JR) Curr Opin Nephrol Hypertens 2003 Jul;12(4):407-14 PMID: 12815337 06/20/2003       15 Citations
  • Generation of kidney transcriptomes using serial analysis of gene expression. (Schelling JR, El-Meanawy MA, Barathan S, Dodig T, Iyengar SK, Sedor JR) Exp Nephrol 2002;10(2):82-92 PMID: 11937755 04/09/2002       12 Citations
  • Use of serial analysis of gene expression to generate kidney expression libraries. (El-Meanawy MA, Schelling JR, Pozuelo F, Churpek MM, Ficker EK, Iyengar S, Sedor JR) Am J Physiol Renal Physiol 2000 Aug;279(2):F383-92 PMID: 10919859 08/05/2000       29 Citations
  • Identification and molecular cloning of a 67-kilodalton protein in Schistosoma japonicum homologous to a family of actin-binding proteins. (Kurtis JD, Ramirez BL, Wiest PM, Dong KL, El-Meanawy A, Petzke MM, Johnson JH, Edmison J, Maier RA Jr, Olds GR) Infect Immun 1997 Jan;65(1):344-7 PMID: 8975937 PMCID: PMC174601 01/01/1997       12 Citations
  • Definition of the complete Schistosoma mansoni hemoglobinase mRNA sequence and gene expression in developing parasites. (el Meanawy MA, Aji T, Phillips NF, Davis RE, Salata RA, Malhotra I, McClain D, Aikawa M, Davis AH) Am J Trop Med Hyg 1990 Jul;43(1):67-78 PMID: 2382765 07/01/1990       32 Citations
  • Last update: 01/04/2019
    jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6