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Jeannette M. Vasquez-Vivar PhD

Jeannette M. Vasquez-Vivar PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Free Radical Research Center

Member of the Cardiovascular Center
Member of the Center for Disease Prevention Research (CDPR)


I am willing to mentor a junior faculty member.


Research Experience

  • Antioxidants
  • Arginine
  • Ascorbic Acid
  • Biomarkers
  • Biopterin
  • Blotting, Western
  • Cerebral Palsy
  • Electron Spin Resonance Spectroscopy
  • Endothelial Cells
  • Ethidium
  • Free Radicals
  • GTP Cyclohydrolase
  • Graft Rejection
  • Heart Transplantation
  • Hydrogen Peroxide
  • Hypoxia-Ischemia, Brain
  • Kinetics
  • Membrane Potential, Mitochondrial
  • Mitochondria
  • Mitochondria, Heart
  • Myocytes, Cardiac
  • NADPH Oxidases
  • Nitric Oxide Synthase
  • Nitric Oxide Synthase Type I
  • Nitric Oxide Synthase Type II
  • Oxidation-Reduction
  • Primaquine
  • Proteins
  • Pterins
  • Reactive Nitrogen Species
  • Reactive Oxygen Species
  • Recombinant Proteins
  • Spin Trapping
  • Structure-Activity Relationship
  • Tetrahydrofolate Dehydrogenase
  • Nitric Oxide Synthase enzymology, Nitric Oxide
  • Hypoxia-ischemia Fetal Brain Injury
  • Free Radicals, Electron Paramagnetic Resonance Spin Trapping
  • Tetrahydrobiopterin, pterins, folates
  • Methodologies and Techniques

  • Brain Diseases, Metabolic, Inborn
  • Cells, Cultured
  • Electron Spin Resonance Spectroscopy
  • Energy Metabolism
  • Fluorescent Dyes
  • Folic Acid Antagonists
  • Kinetics
  • NADP
  • Oxygen Consumption
  • Reactive Oxygen Species
  • Spin Trapping
  • HPLC, chromatography electrochemical, UV and fluorescence detection (Pterins, Neurotransmitters, Glutathione, 2-Hydroxyethidium)
  • Transgenic Mice (endothelial and myocyte targeted overexpression GTPCH); ApoE-/-
  • Leadership Positions

  •  Associate Director, Redox Biology Program
  • MCW Program / Core Facilities

  • Redox Biology
  • Publications (74)

  • In vivo vascular rarefaction and hypertension induced by dexamethasone are related to phosphatase PTP1B activation not endothelial metabolic changes. (Herrera NA, Duchatsch F, Kahlke A, Amaral SL, Vasquez-Vivar J) Free Radic Biol Med 2020 May 20;152:689-696 PMID: 31978540 SCOPUS ID: 2-s2.0-85078237606 01/25/2020    
  • Neuronal vulnerability to fetal hypoxia-reoxygenation injury and motor deficit development relies on regional brain tetrahydrobiopterin levels. (Vasquez-Vivar J, Shi Z, Jeong JW, Luo K, Sharma A, Thirugnanam K, Tan S) Redox Biol 2020 01;29:101407 PMID: 31926630 PMCID: PMC6928344 SCOPUS ID: 2-s2.0-85076556552 01/14/2020       1 Citation
  • Ascending Lipopolysaccharide-Induced Intrauterine Inflammation in Near-Term Rabbits Leading to Newborn Neurobehavioral Deficits. (Shi Z, Vasquez-Vivar J, Luo K, Yan Y, Northington F, Mehrmohammadi M, Tan S) Dev Neurosci 2018;40(5-6):534-546 PMID: 31163416 SCOPUS ID: 2-s2.0-85066972526 06/05/2019       1 Citation
  • Treatment of Cells and Tissues with Chromate Maximizes Mitochondrial 2Fe2S EPR Signals. (Antholine WE, Vasquez-Vivar J, Quirk BJ, Whelan HT, Wu PK, Park JI, Myers CR) Int J Mol Sci 2019 Mar 06;20(5) PMID: 30845710 PMCID: PMC6429069 SCOPUS ID: 2-s2.0-85062628835 03/09/2019       1 Citation
  • Soluble Fms-Like Tyrosine Kinase-1 Alters Cellular Metabolism and Mitochondrial Bioenergetics in Preeclampsia. (Sánchez-Aranguren LC, Espinosa-González CT, González-Ortiz LM, Sanabria-Barrera SM, Riaño-Medina CE, Nuñez AF, Ahmed A, Vasquez-Vivar J, López M) Front Physiol 2018;9:83 PMID: 29563877 PMCID: PMC5845757 03/23/2018    
  • Detection and Characterization of Reactive Oxygen and Nitrogen Species in Biological Systems by Monitoring Species-Specific Products. (Hardy M, Zielonka J, Karoui H, Sikora A, Michalski R, Podsiadły R, Lopez M, Vasquez-Vivar J, Kalyanaraman B, Ouari O) Antioxid Redox Signal 2018 05 20;28(15):1416-1432 PMID: 29037049 PMCID: PMC5910052 SCOPUS ID: 2-s2.0-85045516114 10/19/2017       15 Citations
  • Tetrahydrobiopterin in antenatal brain hypoxia-ischemia-induced motor impairments and cerebral palsy. (Vasquez-Vivar J, Shi Z, Luo K, Thirugnanam K, Tan S) Redox Biol 2017 10;13:594-599 PMID: 28803128 PMCID: PMC5554922 SCOPUS ID: 2-s2.0-85027861384 08/15/2017       5 Citations
  • Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications. (Zielonka J, Joseph J, Sikora A, Hardy M, Ouari O, Vasquez-Vivar J, Cheng G, Lopez M, Kalyanaraman B) Chem Rev 2017 Aug 09;117(15):10043-10120 PMID: 28654243 PMCID: PMC5611849 SCOPUS ID: 2-s2.0-85027303022 06/28/2017       258 Citations
  • Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling. (Liu Y, Baumgardt SL, Fang J, Shi Y, Qiao S, Bosnjak ZJ, Vásquez-Vivar J, Xia Z, Warltier DC, Kersten JR, Ge ZD) Sci Rep 2017 06 08;7(1):3093 PMID: 28596578 PMCID: PMC5465102 SCOPUS ID: 2-s2.0-85020486126 06/10/2017       6 Citations
  • Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions. (Yang M, Cooley BC, Li W, Chen Y, Vasquez-Vivar J, Scoggins NO, Cameron SJ, Morrell CN, Silverstein RL) Blood 2017 05 25;129(21):2917-2927 PMID: 28336528 PMCID: PMC5445574 SCOPUS ID: 2-s2.0-85019661296 03/25/2017       22 Citations
  • Nitric oxide synthases-from genes to function. (Stuehr DJ, Vasquez-Vivar J) Nitric Oxide 2017 02 28;63:29 PMID: 28137371 PMCID: PMC5495577 SCOPUS ID: 2-s2.0-85010723274 02/01/2017       9 Citations
  • Increasing tetrahydrobiopterin in cardiomyocytes adversely affects cardiac redox state and mitochondrial function independently of changes in NO production. (Sethumadhavan S, Whitsett J, Bennett B, Ionova IA, Pieper GM, Vasquez-Vivar J) Free Radic Biol Med 2016 Apr;93:1-11 PMID: 26826575 PMCID: PMC5498285 SCOPUS ID: 2-s2.0-84959375364 01/31/2016       5 Citations
  • Spin-labeled small unilamellar vesicles with the T1-sensitive saturation-recovery EPR display as an oxygen sensitive analyte for measurement of cellular respiration. (Mainali L, Vasquez-Vivar J, Hyde JS, Subczynski WK) Appl Magn Reson 2015 Aug 01;46(8):885-895 PMID: 26441482 PMCID: PMC4591545 10/07/2015    
  • Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats. (Baotic I, Weihrauch D, Procknow J, Vasquez-Vivar J, Ge ZD, Sudhakaran S, Warltier DC, Kersten JR) Anesthesiology 2015 Sep;123(3):582-9 PMID: 26192027 PMCID: PMC4543441 SCOPUS ID: 2-s2.0-84964697044 07/21/2015       8 Citations
  • Rap1 promotes endothelial mechanosensing complex formation, NO release and normal endothelial function. (Lakshmikanthan S, Zheng X, Nishijima Y, Sobczak M, Szabo A, Vasquez-Vivar J, Zhang DX, Chrzanowska-Wodnicka M) EMBO Rep 2015 May;16(5):628-37 PMID: 25807985 PMCID: PMC4428051 SCOPUS ID: 2-s2.0-84928885238 03/27/2015       21 Citations
  • Elevated spinal monoamine neurotransmitters after antenatal hypoxia-ischemia in rabbit cerebral palsy model. (Drobyshevsky A, Takada SH, Luo K, Derrick M, Yu L, Quinlan KA, Vasquez-Vivar J, Nogueira MI, Tan S) J Neurochem 2015 Feb;132(4):394-402 PMID: 25421613 PMCID: PMC4329027 SCOPUS ID: 2-s2.0-84922635309 11/26/2014       4 Citations
  • Mitochondria-targeted spin traps: synthesis, superoxide spin trapping, and mitochondrial uptake. (Hardy M, Poulhés F, Rizzato E, Rockenbauer A, Banaszak K, Karoui H, Lopez M, Zielonka J, Vasquez-Vivar J, Sethumadhavan S, Kalyanaraman B, Tordo P, Ouari O) Chem Res Toxicol 2014 Jul 21;27(7):1155-65 PMID: 24890552 PMCID: PMC5452977 SCOPUS ID: 2-s2.0-84904659978 06/04/2014       18 Citations
  • Developmental susceptibility of neurons to transient tetrahydrobiopterin insufficiency and antenatal hypoxia-ischemia in fetal rabbits. (Yu L, Vásquez-Vivar J, Jiang R, Luo K, Derrick M, Tan S) Free Radic Biol Med 2014 Feb;67:426-36 PMID: 24316196 PMCID: PMC3945116 SCOPUS ID: 2-s2.0-84891668871 12/10/2013       7 Citations
  • Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling. (Whitsett J, Rangel Filho A, Sethumadhavan S, Celinska J, Widlansky M, Vasquez-Vivar J) Free Radic Biol Med 2013 Oct;63:143-50 PMID: 23707606 PMCID: PMC3748942 05/28/2013    
  • Mitochondrial DNA variant for complex I reveals a role in diabetic cardiac remodeling. (Sethumadhavan S, Vasquez-Vivar J, Migrino RQ, Harmann L, Jacob HJ, Lazar J) J Biol Chem 2012 Jun 22;287(26):22174-82 PMID: 22544750 PMCID: PMC3381178 SCOPUS ID: 2-s2.0-84862699122 05/01/2012       19 Citations
  • Motor deficits are triggered by reperfusion-reoxygenation injury as diagnosed by MRI and by a mechanism involving oxidants. (Drobyshevsky A, Luo K, Derrick M, Yu L, Du H, Prasad PV, Vasquez-Vivar J, Batinic-Haberle I, Tan S) J Neurosci 2012 Apr 18;32(16):5500-9 PMID: 22514312 PMCID: PMC3332550 SCOPUS ID: 2-s2.0-84859768476 04/20/2012       25 Citations
  • Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway. (Mao M, Sudhahar V, Ansenberger-Fricano K, Fernandes DC, Tanaka LY, Fukai T, Laurindo FR, Mason RP, Vasquez-Vivar J, Minshall RD, Stadler K, Bonini MG) Free Radic Biol Med 2012 Jan 15;52(2):427-35 PMID: 22037515 PMCID: PMC3432314 SCOPUS ID: 2-s2.0-84855460214 11/01/2011       20 Citations
  • NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction. (Leskov IL, Whitsett J, Vasquez-Vivar J, Stokes KY) Free Radic Biol Med 2011 Dec 15;51(12):2300-8 PMID: 22033010 PMCID: PMC3272703 SCOPUS ID: 2-s2.0-81855198908 10/29/2011       10 Citations
  • Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse. (Belik J, McIntyre BA, Enomoto M, Pan J, Grasemann H, Vasquez-Vivar J) Free Radic Biol Med 2011 Dec 15;51(12):2227-33 PMID: 21982896 PMCID: PMC5050525 SCOPUS ID: 2-s2.0-81855221784 10/11/2011       17 Citations
  • Neuronal nitric oxide synthase inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: comparison between JI-8 and 7-nitroindazole. (Yu L, Derrick M, Ji H, Silverman RB, Whitsett J, Vásquez-Vivar J, Tan S) Dev Neurosci 2011;33(3-4):312-9 PMID: 21659718 PMCID: PMC3225251 SCOPUS ID: 2-s2.0-80255131292 06/11/2011       25 Citations
  • Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia. (Ge ZD, Ionova IA, Vladic N, Pravdic D, Hirata N, Vásquez-Vivar J, Pratt PF Jr, Warltier DC, Pieper GM, Kersten JR) Cardiovasc Res 2011 Jul 15;91(2):340-9 PMID: 21422102 PMCID: PMC3125073 SCOPUS ID: 2-s2.0-79960007388 03/23/2011       20 Citations
  • Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection. (Ionova IA, Vásquez-Vivar J, Cooley BC, Khanna AK, Whitsett J, Herrnreiter A, Migrino RQ, Ge ZD, Regner KR, Channon KM, Alp NJ, Pieper GM) Am J Physiol Heart Circ Physiol 2010 Jul;299(1):H88-96 PMID: 20418482 PMCID: PMC2904123 SCOPUS ID: 2-s2.0-77953745147 04/27/2010       6 Citations
  • Tetrahydrobiopterin in the prevention of hypertonia in hypoxic fetal brain. (Vásquez-Vivar J, Whitsett J, Derrick M, Ji X, Yu L, Tan S) Ann Neurol 2009 Sep;66(3):323-31 PMID: 19798726 PMCID: PMC2785106 SCOPUS ID: 2-s2.0-70350041395 10/03/2009       20 Citations
  • Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I. (Du J, Wei N, Xu H, Ge Y, Vásquez-Vivar J, Guan T, Oldham KT, Pritchard KA Jr, Shi Y) Arterioscler Thromb Vasc Biol 2009 Dec;29(12):2161-8 PMID: 19762783 PMCID: PMC2798731 SCOPUS ID: 2-s2.0-73849125957 09/19/2009       8 Citations
  • Tetrahydrobiopterin, superoxide, and vascular dysfunction. (Vásquez-Vivar J) Free Radic Biol Med 2009 Oct 15;47(8):1108-19 PMID: 19628033 PMCID: PMC2852262 SCOPUS ID: 2-s2.0-70249093891 07/25/2009       56 Citations
  • Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor. (Rabbani ZN, Spasojevic I, Zhang X, Moeller BJ, Haberle S, Vasquez-Vivar J, Dewhirst MW, Vujaskovic Z, Batinic-Haberle I) Free Radic Biol Med 2009 Oct 01;47(7):992-1004 PMID: 19591920 PMCID: PMC2749298 SCOPUS ID: 2-s2.0-69249212132 07/14/2009       65 Citations
  • Sepiapterin decreases acute rejection and apoptosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization. (Pieper GM, Ionova IA, Cooley BC, Migrino RQ, Khanna AK, Whitsett J, Vásquez-Vivar J) J Pharmacol Exp Ther 2009 Jun;329(3):890-9 PMID: 19307452 PMCID: PMC2683770 SCOPUS ID: 2-s2.0-66749102277 03/25/2009       13 Citations
  • Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo. (Hein TW, Singh U, Vasquez-Vivar J, Devaraj S, Kuo L, Jialal I) Atherosclerosis 2009 Sep;206(1):61-8 PMID: 19268941 PMCID: PMC2735606 SCOPUS ID: 2-s2.0-69249242832 03/10/2009       102 Citations
  • Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy. (Ji H, Tan S, Igarashi J, Li H, Derrick M, Martásek P, Roman LJ, Vásquez-Vivar J, Poulos TL, Silverman RB) Ann Neurol 2009 Feb;65(2):209-17 PMID: 19235180 PMCID: PMC2658647 SCOPUS ID: 2-s2.0-62549102043 02/24/2009       63 Citations
  • Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes. (Ionova IA, Vásquez-Vivar J, Whitsett J, Herrnreiter A, Medhora M, Cooley BC, Pieper GM) Am J Physiol Heart Circ Physiol 2008 Nov;295(5):H2178-87 PMID: 18835915 PMCID: PMC2614582 SCOPUS ID: 2-s2.0-57049176060 10/07/2008       26 Citations
  • Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes. (Vásquez-Vivar J, Whitsett J, Ionova I, Konorev E, Zielonka J, Kalyanaraman B, Shi Y, Pieper GM) Free Radic Biol Med 2008 Oct 01;45(7):994-1001 PMID: 18634867 PMCID: PMC2578873 SCOPUS ID: 2-s2.0-51349157985 07/19/2008       12 Citations
  • Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine. (Zielonka J, Vasquez-Vivar J, Kalyanaraman B) Nat Protoc 2008;3(1):8-21 PMID: 18193017 SCOPUS ID: 2-s2.0-38149142769 01/15/2008       254 Citations
  • Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimers. (Zielonka J, Srinivasan S, Hardy M, Ouari O, Lopez M, Vasquez-Vivar J, Avadhani NG, Kalyanaraman B) Free Radic Biol Med 2008 Mar 01;44(5):835-46 PMID: 18155177 PMCID: PMC2692199 SCOPUS ID: 2-s2.0-39149083084 12/25/2007       69 Citations
  • C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling. (Singh U, Devaraj S, Vasquez-Vivar J, Jialal I) J Mol Cell Cardiol 2007 Dec;43(6):780-91 PMID: 17942113 PMCID: PMC2771555 SCOPUS ID: 2-s2.0-36448943247 10/19/2007       97 Citations
  • 4-Hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation. (Whitsett J, Picklo MJ Sr, Vasquez-Vivar J) Arterioscler Thromb Vasc Biol 2007 Nov;27(11):2340-7 PMID: 17872449 SCOPUS ID: 2-s2.0-36048937528 09/18/2007       77 Citations
  • Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap. (Hardy M, Rockenbauer A, Vásquez-Vivar J, Felix C, Lopez M, Srinivasan S, Avadhani N, Tordo P, Kalyanaraman B) Chem Res Toxicol 2007 Jul;20(7):1053-60 PMID: 17559235 PMCID: PMC4455887 SCOPUS ID: 2-s2.0-34547615931 06/15/2007       52 Citations
  • Selective fluorescent imaging of superoxide in vivo using ethidium-based probes. (Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS) Proc Natl Acad Sci U S A 2006 Oct 10;103(41):15038-43 PMID: 17015830 PMCID: PMC1586181 10/04/2006       532 Citations
  • The confounding effects of light, sonication, and Mn(III)TBAP on quantitation of superoxide using hydroethidine. (Zielonka J, Vasquez-Vivar J, Kalyanaraman B) Free Radic Biol Med 2006 Oct 01;41(7):1050-7 PMID: 16962930 SCOPUS ID: 2-s2.0-33748291680 09/12/2006       46 Citations
  • Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution. (Whitsett J, Martásek P, Zhao H, Schauer DW, Hatakeyama K, Kalyanaraman B, Vásquez-Vivar J) Free Radic Biol Med 2006 Jun 01;40(11):2056-68 PMID: 16716906 SCOPUS ID: 2-s2.0-33646555780 05/24/2006       33 Citations
  • Nitric oxide formation in acutely rejecting cardiac allografts correlates with GTP cyclohydrolase I activity. (Pieper GM, Nilakantan V, Halligan NL, Khanna AK, Hilton G, Vásquez-Vivar J) Biochem J 2005 Nov 01;391(Pt 3):541-7 PMID: 16000090 PMCID: PMC1276954 SCOPUS ID: 2-s2.0-27744545620 07/08/2005       8 Citations
  • Erratum: Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence (Proceedings of the National Academy of Sciences of the United States of America (April 19, 2005) 102, 16 (5727-5732)) (Zhao H, Joseph J, Fales HM, Sokoloski EA, Levine RL, Vasquez-Vivar J, Kalyanaraman B) Proceedings of the National Academy of Sciences of the United States of America 21 June 2005;102(25):9086 SCOPUS ID: 2-s2.0-21144455244 06/21/2005    
  • Reductive activation of Cr(Vi) by nitric oxide synthase. (Porter R, Jáchymová M, Martásek P, Kalyanaraman B, Vásquez-Vivar J) Chem Res Toxicol 2005 May;18(5):834-43 PMID: 15892577 SCOPUS ID: 2-s2.0-18944406786 05/17/2005       15 Citations
  • Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. (Zhao H, Joseph J, Fales HM, Sokoloski EA, Levine RL, Vasquez-Vivar J, Kalyanaraman B) Proc Natl Acad Sci U S A 2005 Apr 19;102(16):5727-32 PMID: 15824309 PMCID: PMC556312 SCOPUS ID: 2-s2.0-17644394600 04/13/2005       431 Citations
  • Changes in tetrahydrobiopterin levels in endothelial cells and adult cardiomyocytes induced by LPS and hydrogen peroxide--a role for GFRP? (Kalivendi S, Hatakeyama K, Whitsett J, Konorev E, Kalyanaraman B, Vásquez-Vivar J) Free Radic Biol Med 2005 Feb 15;38(4):481-91 PMID: 15649650 SCOPUS ID: 2-s2.0-13844266737 01/15/2005       37 Citations
  • Rapid-onset endothelial dysfunction with adriamycin: evidence for a dysfunctional nitric oxide synthase. (Duquaine D, Hirsch GA, Chakrabarti A, Han Z, Kehrer C, Brook R, Joseph J, Schott A, Kalyanaraman B, Vasquez-Vivar J, Rajagopalan S) Vasc Med 2003 May;8(2):101-7 PMID: 14518612 SCOPUS ID: 2-s2.0-0141607692 10/02/2003       52 Citations
  • Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. (Zhao H, Kalivendi S, Zhang H, Joseph J, Nithipatikom K, Vásquez-Vivar J, Kalyanaraman B) Free Radic Biol Med 2003 Jun 01;34(11):1359-68 PMID: 12757846 SCOPUS ID: 2-s2.0-0038368985 05/22/2003       587 Citations
  • The role of tetrahydrobiopterin in superoxide generation from eNOS: enzymology and physiological implications. (Vásquez-Vivar J, Kalyanaraman B, Martásek P) Free Radic Res 2003 Feb;37(2):121-7 PMID: 12653200 03/26/2003       167 Citations
  • Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants. (Vásquez-Vivar J, Duquaine D, Whitsett J, Kalyanaraman B, Rajagopalan S) Arterioscler Thromb Vasc Biol 2002 Oct 01;22(10):1655-61 PMID: 12377745 SCOPUS ID: 2-s2.0-0036790604 10/16/2002       106 Citations
  • The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. (Vásquez-Vivar J, Martásek P, Whitsett J, Joseph J, Kalyanaraman B) Biochem J 2002 Mar 15;362(Pt 3):733-9 PMID: 11879202 PMCID: PMC1222439 SCOPUS ID: 2-s2.0-0037086565 03/07/2002       229 Citations
  • Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical. (Vásquez-Vivar J, Whitsett J, Martásek P, Hogg N, Kalyanaraman B) Free Radic Biol Med 2001 Oct 15;31(8):975-85 PMID: 11595382 SCOPUS ID: 2-s2.0-0035887885 10/12/2001       92 Citations
  • Generation of superoxide from nitric oxide synthase. (Vásquez-Vivar J, Kalyanaraman B) FEBS Lett 2000 Sep 22;481(3):305-6 PMID: 11041680 SCOPUS ID: 2-s2.0-0342844298 10/21/2000       32 Citations
  • Detection of superoxide anion using an isotopically labeled nitrone spin trap: potential biological applications. (Zhang H, Joseph J, Vasquez-Vivar J, Karoui H, Nsanzumuhire C, Martásek P, Tordo P, Kalyanaraman B) FEBS Lett 2000 May 04;473(1):58-62 PMID: 10802059 SCOPUS ID: 2-s2.0-0034604057 05/10/2000       141 Citations
  • Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation. (Vasquez-Vivar J, Kalyanaraman B, Kennedy MC) J Biol Chem 2000 May 12;275(19):14064-9 PMID: 10799480 SCOPUS ID: 2-s2.0-0039174315 05/09/2000       232 Citations
  • Effect of redox-active drugs on superoxide generation from nitric oxide synthases: biological and toxicological implications. (Vásquez-Vivar J, Hogg N, Martásek P, Karoui H, Tordo P, Pritchard KA Jr, Kalyanaraman B) Free Radic Res 1999 Dec;31(6):607-17 PMID: 10630684 SCOPUS ID: 2-s2.0-0344146555 01/12/2000       27 Citations
  • EPR spin trapping of superoxide from nitric oxide synthase (Vasquez-Vivar J, Joseph J, Karoui H, Zhang H, Miller J, Martasek P) Analusis Jul;28(6):487-492 SCOPUS ID: 2-s2.0-0034231039 01/01/2000    
  • Tetrahydrobiopterin-dependent inhibition of superoxide generation from neuronal nitric oxide synthase. (Vásquez-Vivar J, Hogg N, Martásek P, Karoui H, Pritchard KA Jr, Kalyanaraman B) J Biol Chem 1999 Sep 17;274(38):26736-42 PMID: 10480877 SCOPUS ID: 2-s2.0-0040886300 09/10/1999       159 Citations
  • Electron spin resonance spin-trapping detection of superoxide generated by neuronal nitric oxide synthase. (Vásquez-Vivar J, Martásek P, Hogg N, Karoui H, Masters BS, Pritchard KA Jr, Kalyanaraman B) Methods Enzymol 1999;301:169-77 PMID: 9919565 SCOPUS ID: 2-s2.0-0031795460 01/27/1999       36 Citations
  • Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. (Vásquez-Vivar J, Kalyanaraman B, Martásek P, Hogg N, Masters BS, Karoui H, Tordo P, Pritchard KA Jr) Proc Natl Acad Sci U S A 1998 Aug 04;95(16):9220-5 PMID: 9689061 PMCID: PMC21319 SCOPUS ID: 2-s2.0-0032482975 08/05/1998       1151 Citations
  • Formation of spin trap adducts during the decomposition of peroxynitrite. (Gatti RM, Alvarez B, Vasquez-Vivar J, Radi R, Augusto O) Arch Biochem Biophys 1998 Jan 01;349(1):36-46 PMID: 9439580 SCOPUS ID: 2-s2.0-0031816583 01/24/1998       64 Citations
  • Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. (Vásquez-Vivar J, Martasek P, Hogg N, Masters BS, Pritchard KA Jr, Kalyanaraman B) Biochemistry 1997 Sep 23;36(38):11293-7 PMID: 9333325 SCOPUS ID: 2-s2.0-19244383998 10/23/1997       269 Citations
  • Peroxynitrite-mediated decarboxylation of pyruvate to both carbon dioxide and carbon dioxide radical anion. (Vásquez-Vivar J, Denicola A, Radi R, Augusto O) Chem Res Toxicol 1997 Jul;10(7):786-94 PMID: 9250413 SCOPUS ID: 2-s2.0-0343580474 07/01/1997       65 Citations
  • Superoxide anion formation from lucigenin: an electron spin resonance spin-trapping study. (Vásquez-Vivar J, Hogg N, Pritchard KA Jr, Martasek P, Kalyanaraman B) FEBS Lett 1997 Feb 17;403(2):127-30 PMID: 9042951 SCOPUS ID: 2-s2.0-0242502758 02/17/1997       185 Citations
  • Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicals. (Vásquez-Vivar J, Santos AM, Junqueira VB, Augusto O) Biochem J 1996 Mar 15;314 ( Pt 3):869-76 PMID: 8615782 PMCID: PMC1217137 SCOPUS ID: 2-s2.0-0029997642 03/15/1996       121 Citations
  • Detection of secondary radicals from peroxynitrite-medicated oxidations by electron spin resonance. (Augusto O, Radi R, Gatti RM, Vásquez-Vivar J) Methods Enzymol 1996;269:346-54 PMID: 8791663 SCOPUS ID: 2-s2.0-0029792288 01/01/1996       15 Citations
  • Oxidative activity of primaquine metabolites on rat erythrocytes in vitro and in vivo. (Vásquez-Vivar J, Augusto O) Biochem Pharmacol 1994 Jan 20;47(2):309-16 PMID: 8304975 SCOPUS ID: 2-s2.0-0028047135 01/20/1994       39 Citations
  • OXIDATION OF INDOLE‐3‐ACETIC ACID BY SONICATED NEUTROPHILS. PITFALLS IN CORRELATING EPR SIGNALS AND CHEMILUMINESCENCE (Escobar JA, Vásquez‐Vivar J, Cilento G) Photochemistry and Photobiology January 1994;59(1):130-134 SCOPUS ID: 2-s2.0-0028045391 01/01/1994    
  • Free radicals and excited species in the metabolism of indole-3-acetic acid and its ethyl ester by horseradish peroxidase and by neutrophils. (Escobar JA, Vásquez-Vivar J, Cilento G) Photochem Photobiol 1992 Jun;55(6):895-902 PMID: 1329121 SCOPUS ID: 2-s2.0-0026870640 06/01/1992       32 Citations
  • Hydroxylated metabolites of the antimalarial drug primaquine. Oxidation and redox cycling. (Vásquez-Vivar J, Augusto O) J Biol Chem 1992 Apr 05;267(10):6848-54 PMID: 1313024 SCOPUS ID: 2-s2.0-0026630568 04/05/1992       71 Citations
  • ESR detection of free radical intermediates during autoxidation of 5-hydroxyprimaquine. (Vasquez-Vivar J, Augusto O) Free Radic Res Commun 1990;9(3-6):383-9 PMID: 2167276 SCOPUS ID: 2-s2.0-0025013036 01/01/1990       5 Citations
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