Medical College of Wisconsin
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Mary Sorci Thomas PhD

Mary Sorci Thomas PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Research

Member of the Cancer Center
Member of the Cardiovascular Center


I am willing to mentor a junior faculty member.
I am willing to collaborate on research projects.


Research Experience

  • Atherosclerosis
  • Cholesterol, HDL
  • Macrophages
  • Stem Cells
  • Vascular Endothelial Growth Factors
  • Publications (79)

  • Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism. (Li Z, Votava JA, Zajac GJM, Nguyen JN, Leyva Jaimes FB, Ly SM, Brinkman JA, De Giorgi M, Kaul S, Green CL, St Clair SL, Belisle SL, Rios JM, Nelson DW, Sorci-Thomas MG, Lagor WR, Lamming DW, Eric Yen CL, Parks BW) Cell Metab 2020 Apr 07;31(4):741-754.e5 PMID: 32197071 PMCID: PMC7184639 03/21/2020       2 Citations
  • The ins and outs of lipid rafts: functions in intracellular cholesterol homeostasis, microparticles, and cell membranes. (Ouweneel AB, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2020 May;61(5):676-686 PMID: 31888980 PMCID: PMC7193959 SCOPUS ID: 2-s2.0-85084961109 01/01/2020       3 Citations
  • Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease. (Rodriguez A, Trigatti BL, Mineo C, Knaack D, Wilkins JT, Sahoo D, Asztalos BF, Mora S, Cuchel M, Pownall HJ, Rosales C, Bernatchez P, Ribeiro Martins da Silva A, Getz GS, Barber JL, Shearer GC, Zivkovic AM, Tietge UJF, Sacks FM, Connelly MA, Oda MN, Davidson WS, Sorci-Thomas MG, Vaisar T, Ruotolo G, Vickers KC, Martel C) Arterioscler Thromb Vasc Biol 2019 12;39(12):2457-2467 PMID: 31597448 PMCID: PMC6937204 SCOPUS ID: 2-s2.0-85075813183 10/11/2019       1 Citation
  • Recombinant LCAT (Lecithin:Cholesterol Acyltransferase) Rescues Defective HDL (High-Density Lipoprotein)-Mediated Endothelial Protection in Acute Coronary Syndrome. (Ossoli A, Simonelli S, Varrenti M, Morici N, Oliva F, Stucchi M, Gomaraschi M, Strazzella A, Arnaboldi L, Thomas MJ, Sorci-Thomas MG, Corsini A, Veglia F, Franceschini G, Karathanasis SK, Calabresi L) Arterioscler Thromb Vasc Biol 2019 05;39(5):915-924 PMID: 30894011 SCOPUS ID: 2-s2.0-85065216772 03/22/2019       8 Citations
  • Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (Huang LH, Zinselmeyer BH, Chang CH, Saunders BT, Elvington A, Baba O, Broekelmann TJ, Qi L, Rueve JS, Swartz MA, Kim BS, Mecham RP, Wiig H, Thomas MJ, Sorci-Thomas MG, Randolph GJ) Cell Metab 2019 02 05;29(2):475-487.e7 PMID: 30415924 PMCID: PMC6365189 SCOPUS ID: 2-s2.0-85060717940 11/13/2018       10 Citations
  • Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. (Gaddis DE, Padgett LE, Wu R, McSkimming C, Romines V, Taylor AM, McNamara CA, Kronenberg M, Crotty S, Thomas MJ, Sorci-Thomas MG, Hedrick CC) Nat Commun 2018 03 15;9(1):1095 PMID: 29545616 PMCID: PMC5854619 SCOPUS ID: 2-s2.0-85044288848 03/17/2018       25 Citations
  • High-Density Lipoprotein Functionality as a New Pharmacological Target on Cardiovascular Disease: Unifying Mechanism That Explains High-Density Lipoprotein Protection Toward the Progression of Atherosclerosis. (Favari E, Thomas MJ, Sorci-Thomas MG) J Cardiovasc Pharmacol 2018 06;71(6):325-331 PMID: 29528874 SCOPUS ID: 2-s2.0-85051788295 03/13/2018       10 Citations
  • A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state. (Melchior JT, Walker RG, Cooke AL, Morris J, Castleberry M, Thompson TB, Jones MK, Song HD, Rye KA, Oda MN, Sorci-Thomas MG, Thomas MJ, Heinecke JW, Mei X, Atkinson D, Segrest JP, Lund-Katz S, Phillips MC, Davidson WS) Nat Struct Mol Biol 2017 Dec;24(12):1093-1099 PMID: 29131142 PMCID: PMC5749415 SCOPUS ID: 2-s2.0-85039561595 11/14/2017       17 Citations
  • Apolipoprotein A-I Modulates Atherosclerosis Through Lymphatic Vessel-Dependent Mechanisms in Mice. (Milasan A, Jean G, Dallaire F, Tardif JC, Merhi Y, Sorci-Thomas M, Martel C) J Am Heart Assoc 2017 Sep 22;6(9) PMID: 28939717 PMCID: PMC5634311 09/25/2017       7 Citations
  • Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood. (Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ) Circ Res 2017 Sep 01;121(6):662-676 PMID: 28696252 PMCID: PMC5718914 07/12/2017       12 Citations
  • Anti-inflammatory liaisons: T regulatory cells and HDL. (Sorci-Thomas MG, Thomas MJ) J Lipid Res 2017 08;58(8):1491-1492 PMID: 28630261 PMCID: PMC5538272 SCOPUS ID: 2-s2.0-85026671098 06/21/2017       1 Citation
  • AIBP, NAXE, and Angiogenesis: What's in a Name? (Sorci-Thomas MG, Thomas MJ) Circ Res 2017 05 26;120(11):1690-1691 PMID: 28546345 PMCID: PMC5497770 SCOPUS ID: 2-s2.0-85019757650 05/27/2017       3 Citations
  • Rediscovering scavenger receptor type BI: surprising new roles for the HDL receptor. (Hoekstra M, Sorci-Thomas M) Curr Opin Lipidol 2017 Jun;28(3):255-260 PMID: 28301373 PMCID: PMC5523812 03/17/2017       5 Citations
  • S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. (Lee MH, Appleton KM, El-Shewy HM, Sorci-Thomas MG, Thomas MJ, Lopes-Virella MF, Luttrell LM, Hammad SM, Klein RL) J Lipid Res 2017 02;58(2):325-338 PMID: 27881715 PMCID: PMC5282949 SCOPUS ID: 2-s2.0-85011295067 11/25/2016       12 Citations
  • Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio. (Kaul S, Xu H, Zabalawi M, Maruko E, Fulp BE, Bluemn T, Brzoza-Lewis KL, Gerelus M, Weerasekera R, Kallinger R, James R, Zhang YS, Thomas MJ, Sorci-Thomas MG) J Am Heart Assoc 2016 11 07;5(11) PMID: 27821400 PMCID: PMC5210328 SCOPUS ID: 2-s2.0-85032586305 11/09/2016       10 Citations
  • High-Density Lipoprotein Biogenesis: Defining the Domains Involved in Human Apolipoprotein A-I Lipidation. (Pollard RD, Fulp B, Sorci-Thomas MG, Thomas MJ) Biochemistry 2016 09 06;55(35):4971-81 PMID: 27501467 PMCID: PMC5356376 SCOPUS ID: 2-s2.0-84985914329 08/09/2016       10 Citations
  • Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. (Cheng HY, Gaddis DE, Wu R, McSkimming C, Haynes LD, Taylor AM, McNamara CA, Sorci-Thomas M, Hedrick CC) J Clin Invest 2016 09 01;126(9):3236-46 PMID: 27482882 PMCID: PMC5004951 08/03/2016       23 Citations
  • Microdomains, Inflammation, and Atherosclerosis. (Sorci-Thomas MG, Thomas MJ) Circ Res 2016 Feb 19;118(4):679-91 PMID: 26892966 PMCID: PMC5291489 SCOPUS ID: 2-s2.0-84959058398 02/20/2016       74 Citations
  • Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses. (Navratil AR, Vozenilek AE, Cardelli JA, Green JM, Thomas MJ, Sorci-Thomas MG, Orr AW, Woolard MD) Atherosclerosis 2015 Oct;242(2):424-32 PMID: 26288136 PMCID: PMC4712446 SCOPUS ID: 2-s2.0-84939606543 08/20/2015       9 Citations
  • What does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport? (Sorci-Thomas MG, Pollard RD, Thomas MJ) Curr Opin Lipidol 2015 Oct;26(5):420-5 PMID: 26218419 PMCID: PMC4564020 SCOPUS ID: 2-s2.0-84944345774 07/29/2015       6 Citations
  • SAA: a link between cholesterol efflux capacity and inflammation? (Thomas MJ, Sorci-Thomas MG) J Lipid Res 2015 Aug;56(8):1383-5 PMID: 26078331 PMCID: PMC4513981 SCOPUS ID: 2-s2.0-84940521694 06/17/2015       5 Citations
  • Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice. (Liu J, Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Sorci-Thomas M, Cassis LA, Daugherty A) Arterioscler Thromb Vasc Biol 2015 Aug;35(8):1826-34 PMID: 26044581 PMCID: PMC4514578 06/06/2015       16 Citations
  • Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake. (Pollard RD, Blesso CN, Zabalawi M, Fulp B, Gerelus M, Zhu X, Lyons EW, Nuradin N, Francone OL, Li XA, Sahoo D, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2015 Jun 19;290(25):15496-511 PMID: 25947382 PMCID: PMC4505464 SCOPUS ID: 2-s2.0-84939623747 05/08/2015       14 Citations
  • Acrolein impairs the cholesterol transport functions of high density lipoproteins. (Chadwick AC, Holme RL, Chen Y, Thomas MJ, Sorci-Thomas MG, Silverstein RL, Pritchard KA Jr, Sahoo D) PLoS One 2015;10(4):e0123138 PMID: 25849485 PMCID: PMC4388475 SCOPUS ID: 2-s2.0-84927672521 04/08/2015       18 Citations
  • Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL. (Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S) J Lipid Res 2015 Mar;56(3):635-43 PMID: 25593328 PMCID: PMC4340310 01/17/2015       17 Citations
  • Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression. (Gao M, Zhao D, Schouteden S, Sorci-Thomas MG, Van Veldhoven PP, Eggermont K, Liu G, Verfaillie CM, Feng Y) Arterioscler Thromb Vasc Biol 2014 Sep;34(9):1900-9 PMID: 24969774 PMCID: PMC4140992 06/28/2014       33 Citations
  • Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. (Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS) J Biol Chem 2014 Jan 31;289(5):2801-14 PMID: 24318881 PMCID: PMC3908412 SCOPUS ID: 2-s2.0-84893431254 12/10/2013       44 Citations
  • The conformation of lipid-free human apolipoprotein A-I in solution. (Pollard RD, Fulp B, Samuel MP, Sorci-Thomas MG, Thomas MJ) Biochemistry 2013 Dec 31;52(52):9470-81 PMID: 24308268 PMCID: PMC3926756 12/07/2013    
  • Why targeting HDL should work as a therapeutic tool, but has not. (Sorci-Thomas MG, Thomas MJ) J Cardiovasc Pharmacol 2013 Sep;62(3):239-46 PMID: 23743767 PMCID: PMC3772973 SCOPUS ID: 2-s2.0-84884671413 06/08/2013       25 Citations
  • Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. (Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ) J Clin Invest 2013 Apr;123(4):1571-9 PMID: 23524964 PMCID: PMC3613904 SCOPUS ID: 2-s2.0-84875873877 03/26/2013       157 Citations
  • High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. (Sorci-Thomas MG, Thomas MJ) Arterioscler Thromb Vasc Biol 2012 Nov;32(11):2561-5 PMID: 23077142 PMCID: PMC3793253 SCOPUS ID: 2-s2.0-84871865547 10/19/2012       65 Citations
  • Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers. (Sorci-Thomas MG, Owen JS, Fulp B, Bhat S, Zhu X, Parks JS, Shah D, Jerome WG, Gerelus M, Zabalawi M, Thomas MJ) J Lipid Res 2012 Sep;53(9):1890-909 PMID: 22750655 PMCID: PMC3413229 SCOPUS ID: 2-s2.0-84864851111 07/04/2012       80 Citations
  • Dysfunctional HDL containing L159R ApoA-I leads to exacerbation of atherosclerosis in hyperlipidemic mice. (Sorci-Thomas MG, Zabalawi M, Bharadwaj MS, Wilhelm AJ, Owen JS, Asztalos BF, Bhat S, Thomas MJ) Biochim Biophys Acta 2012 Mar;1821(3):502-12 PMID: 21944998 PMCID: PMC3690280 SCOPUS ID: 2-s2.0-84857635187 09/29/2011       14 Citations
  • Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. (Potteaux S, Gautier EL, Hutchison SB, van Rooijen N, Rader DJ, Thomas MJ, Sorci-Thomas MG, Randolph GJ) J Clin Invest 2011 May;121(5):2025-36 PMID: 21505265 PMCID: PMC3083793 SCOPUS ID: 2-s2.0-79955503060 04/21/2011       231 Citations
  • Apolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice. (Wilhelm AJ, Zabalawi M, Owen JS, Shah D, Grayson JM, Major AS, Bhat S, Gibbs DP Jr, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2010 Nov 12;285(46):36158-69 PMID: 20833724 PMCID: PMC2975238 SCOPUS ID: 2-s2.0-77958478114 09/14/2010       78 Citations
  • Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles. (Bhat S, Sorci-Thomas MG, Calabresi L, Samuel MP, Thomas MJ) Biochemistry 2010 Jun 29;49(25):5213-24 PMID: 20524691 PMCID: PMC2946800 SCOPUS ID: 2-s2.0-77953891139 06/08/2010       16 Citations
  • Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70 PMID: 20498409 PMCID: PMC2918439 SCOPUS ID: 2-s2.0-77956861083 05/26/2010       53 Citations
  • Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. (Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2009 Jun;29(6):843-9 PMID: 19286630 PMCID: PMC2761013 SCOPUS ID: 2-s2.0-66349139424 03/17/2009       86 Citations
  • Activation of lecithin:cholesterol acyltransferase by HDL ApoA-I central helices. (Sorci-Thomas MG, Bhat S, Thomas MJ) Clin Lipidol 2009 Feb;4(1):113-124 PMID: 20582235 PMCID: PMC2891274 02/01/2009    
  • Three-dimensional models of HDL apoA-I: implications for its assembly and function. (Thomas MJ, Bhat S, Sorci-Thomas MG) J Lipid Res 2008 Sep;49(9):1875-83 PMID: 18515783 PMCID: PMC2515525 SCOPUS ID: 2-s2.0-53149092105 06/03/2008       87 Citations
  • Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes. (Bhat S, Sorci-Thomas MG, Tuladhar R, Samuel MP, Thomas MJ) Biochemistry 2007 Jul 03;46(26):7811-21 PMID: 17563120 PMCID: PMC2553278 SCOPUS ID: 2-s2.0-34347356570 06/15/2007       63 Citations
  • Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin. (Owen JS, Bharadwaj MS, Thomas MJ, Bhat S, Samuel MP, Sorci-Thomas MG) J Lipid Res 2007 Jan;48(1):226-34 PMID: 17071967 SCOPUS ID: 2-s2.0-33845972961 10/31/2006       9 Citations
  • Inflammation and skin cholesterol in LDLr-/-, apoA-I-/- mice: link between cholesterol homeostasis and self-tolerance? (Zabalawi M, Bharadwaj M, Horton H, Cline M, Willingham M, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2007 Jan;48(1):52-65 PMID: 17071966 SCOPUS ID: 2-s2.0-33846007994 10/31/2006       33 Citations
  • The use of chemical cross-linking and mass spectrometry to elucidate the tertiary conformation of lipid-bound apolipoprotein A-I. (Thomas MJ, Bhat S, Sorci-Thomas MG) Curr Opin Lipidol 2006 Jun;17(3):214-20 PMID: 16680024 SCOPUS ID: 2-s2.0-33646858367 05/09/2006       20 Citations
  • Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. (Ou J, Wang J, Xu H, Ou Z, Sorci-Thomas MG, Jones DW, Signorino P, Densmore JC, Kaul S, Oldham KT, Pritchard KA Jr) Circ Res 2005 Nov 25;97(11):1190-7 PMID: 16224061 PMCID: PMC1480357 SCOPUS ID: 2-s2.0-33644675579 10/15/2005       101 Citations
  • Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry. (Bhat S, Sorci-Thomas MG, Alexander ET, Samuel MP, Thomas MJ) J Biol Chem 2005 Sep 23;280(38):33015-25 PMID: 15972827 SCOPUS ID: 2-s2.0-25444491569 06/24/2005       84 Citations
  • Apolipoprotein A-I helix 6 negatively charged residues attenuate lecithin-cholesterol acyltransferase (LCAT) reactivity. (Alexander ET, Bhat S, Thomas MJ, Weinberg RB, Cook VR, Bharadwaj MS, Sorci-Thomas M) Biochemistry 2005 Apr 12;44(14):5409-19 PMID: 15807534 SCOPUS ID: 2-s2.0-16844370698 04/06/2005       32 Citations
  • Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions. (Bhat S, Zabalawi M, Willingham MC, Shelness GS, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2004 Jul;45(7):1207-20 PMID: 15060083 SCOPUS ID: 2-s2.0-3042651483 04/03/2004       9 Citations
  • Induction of fatal inflammation in LDL receptor and ApoA-I double-knockout mice fed dietary fat and cholesterol. (Zabalawi M, Bhat S, Loughlin T, Thomas MJ, Alexander E, Cline M, Bullock B, Willingham M, Sorci-Thomas MG) Am J Pathol 2003 Sep;163(3):1201-13 PMID: 12937162 PMCID: PMC1868257 SCOPUS ID: 2-s2.0-0041924007 08/26/2003       48 Citations
  • Alpha-tocopherol protects against diet induced atherosclerosis in New Zealand white rabbits. (Schwenke DC, Rudel LL, Sorci-Thomas MG, Thomas MJ) J Lipid Res 2002 Nov;43(11):1927-38 PMID: 12401892 SCOPUS ID: 2-s2.0-0036847082 10/29/2002       24 Citations
  • ApoA-I structure on discs and spheres. Variable helix registry and conformational states. (Li HH, Lyles DS, Pan W, Alexander E, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2002 Oct 18;277(42):39093-101 PMID: 12167653 SCOPUS ID: 2-s2.0-0037131260 08/09/2002       66 Citations
  • The effects of altered apolipoprotein A-I structure on plasma HDL concentration. (Sorci-Thomas MG, Thomas MJ) Trends Cardiovasc Med 2002 Apr;12(3):121-8 PMID: 12007737 SCOPUS ID: 2-s2.0-0036234218 05/15/2002       159 Citations
  • Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. (Reschly EJ, Sorci-Thomas MG, Davidson WS, Meredith SC, Reardon CA, Getz GS) J Biol Chem 2002 Mar 22;277(12):9645-54 PMID: 11744719 12/18/2001       35 Citations
  • Preparation and incorporation of probe-labeled apoA-I for fluorescence resonance energy transfer studies of rHDL. (Li HH, Thomas MJ, Pan W, Alexander E, Samuel M, Sorci-Thomas MG) J Lipid Res 2001 Dec;42(12):2084-91 PMID: 11734582 SCOPUS ID: 2-s2.0-0035664834 12/06/2001       17 Citations
  • Isoprostane levels in lipids extracted from atherosclerotic arteries of nonhuman primates. (Thomas MJ, Chen Q, Sorci-Thomas MG, Rudel LL) Free Radic Biol Med 2001 Jun 15;30(12):1337-46 PMID: 11390178 SCOPUS ID: 2-s2.0-0035877154 06/08/2001       11 Citations
  • Is the oxidation of high-density lipoprotein lipids different than the oxidation of low-density lipoprotein lipids? (Thomas MJ, Chen Q, Zabalawi M, Anderson R, Wilson M, Weinberg R, Sorci-Thomas MG, Rudel LL) Biochemistry 2001 Feb 13;40(6):1719-24 PMID: 11327832 SCOPUS ID: 2-s2.0-0035852830 05/01/2001       17 Citations
  • Structural determination of lipid-bound ApoA-I using fluorescence resonance energy transfer. (Li H, Lyles DS, Thomas MJ, Pan W, Sorci-Thomas MG) J Biol Chem 2000 Nov 24;275(47):37048-54 PMID: 10956648 SCOPUS ID: 2-s2.0-0034711217 08/25/2000       82 Citations
  • Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice. (Sorci-Thomas MG, Thomas M, Curtiss L, Landrum M) J Biol Chem 2000 Apr 21;275(16):12156-63 PMID: 10766851 SCOPUS ID: 2-s2.0-0034697316 04/15/2000       41 Citations
  • The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation. (Sorci-Thomas MG, Curtiss L, Parks JS, Thomas MJ, Kearns MW, Landrum M) J Biol Chem 1998 May 08;273(19):11776-82 PMID: 9565601 SCOPUS ID: 2-s2.0-0032496221 06/13/1998       71 Citations
  • Sex steroids increase cholesterol 7alpha-hydroxylase mRNA in nonhuman primates. (Colvin PL Jr, Wagner JD, Adams MR, Sorci-Thomas MG) Metabolism 1998 Apr;47(4):391-5 PMID: 9550534 04/29/1998       18 Citations
  • Alteration in apolipoprotein A-I 22-mer repeat order results in a decrease in lecithin:cholesterol acyltransferase reactivity. (Sorci-Thomas MG, Curtiss L, Parks JS, Thomas MJ, Kearns MW) J Biol Chem 1997 Mar 14;272(11):7278-84 PMID: 9054424 SCOPUS ID: 2-s2.0-0030906053 03/14/1997       57 Citations
  • High level secretion of wild-type and mutant forms of human proapoA-I using baculovirus-mediated Sf-9 cell expression. (Sorci-Thomas MG, Parks JS, Kearns MW, Pate GN, Zhang C, Thomas MJ) J Lipid Res 1996 Mar;37(3):673-83 PMID: 8728328 SCOPUS ID: 2-s2.0-0029916540 03/01/1996       43 Citations
  • Glycosylation structure and enzyme activity of lecithin:cholesterol acyltransferase from human plasma, HepG2 cells, and baculoviral and Chinese hamster ovary cell expression systems. (Miller KR, Wang J, Sorci-Thomas M, Anderson RA, Parks JS) J Lipid Res 1996 Mar;37(3):551-61 PMID: 8728318 03/01/1996       26 Citations
  • Cortisol up-regulates corticotropin releasing factor gene expression in the fetal ovine brainstem at 0.70 gestation. (Keiger CJ, O'Steen WK, Brewer G, Sorci-Thomas M, Zehnder TJ, Rose JC) Brain Res Mol Brain Res 1995 Aug;32(1):75-81 PMID: 7494465 08/01/1995       6 Citations
  • Species-specific polymorphism in the promoter of the apolipoprotein A-I gene: restoration of human transcriptional efficiency by substitution at positions -189, -144 and -48 bp. (Sorci-Thomas M, Kearns MW) Biochim Biophys Acta 1995 Jun 06;1256(3):387-95 PMID: 7786904 06/06/1995       2 Citations
  • Estrogen modulates the inducible expression of platelet-derived growth factor mRNA by monocyte/macrophages. (Shanker G, Sorci-Thomas M, Adams MR) Life Sci 1995;56(7):499-507 PMID: 7869830 01/01/1995       41 Citations
  • Estrogen modulates the expression of tumor necrosis factor alpha mRNA in phorbol ester-stimulated human monocytic THP-1 cells. (Shanker G, Sorci-Thomas M, Adams MR) Lymphokine Cytokine Res 1994 Dec;13(6):377-82 PMID: 7703311 12/01/1994       65 Citations
  • Corticotropin releasing factor mRNA and peptide levels are differentially regulated in the developing ovine brain. (Keiger CJ, O'Steen WK, Brewer G, Sorci-Thomas M, Zehnder TJ, Rose JC) Brain Res Mol Brain Res 1994 Nov;27(1):103-10 PMID: 7877440 11/01/1994       3 Citations
  • The inducible expression of THP-1 cell interleukin-1 mRNA: effects of estrogen on differential response to phorbol ester and lipopolysaccharide. (Shanker G, Sorci-Thomas M, Register TC, Adams MR) Lymphokine Cytokine Res 1994 Feb;13(1):1-7 PMID: 8186319 02/01/1994       16 Citations
  • Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells. (Ettinger WH, Varma VK, Sorci-Thomas M, Parks JS, Sigmon RC, Smith TK, Verdery RB) Arterioscler Thromb 1994 Jan;14(1):8-13 PMID: 8274481 01/01/1994       144 Citations
  • Oral contraceptives decrease hepatic cholesterol independent of the LDL receptor in nonhuman primates. (Colvin PL Jr, Wagner JD, Heuser MD, Sorci-Thomas MG) Arterioscler Thromb 1993 Nov;13(11):1645-9 PMID: 8218105 11/01/1993       5 Citations
  • Apolipoprotein A-I domains involved in lecithin-cholesterol acyltransferase activation. Structure:function relationships. (Sorci-Thomas M, Kearns MW, Lee JP) J Biol Chem 1993 Oct 05;268(28):21403-9 PMID: 8407982 10/05/1993       116 Citations
  • Dexamethasone increases apolipoprotein A-I concentrations in medium and apolipoprotein A-I mRNA abundance from Hep G2 cells. (Varma VK, Smith TK, Sorci-Thomas M, Ettinger WH Jr) Metabolism 1992 Oct;41(10):1075-80 PMID: 1328818 10/11/1992       17 Citations
  • HepG2 cell LDL receptor activity and the accumulation of apolipoprotein B and E in response to docosahexaenoic acid and cholesterol. (Sorci-Thomas M, Hendricks CL, Kearns MW) J Lipid Res 1992 Aug;33(8):1147-56 PMID: 1431595 08/01/1992       20 Citations
  • Transcriptional regulation of the apolipoprotein A-I gene. Species-specific expression correlates with rates of gene transcription. (Sorci-Thomas M, Kearns MW) J Biol Chem 1991 Sep 25;266(27):18045-50 PMID: 1917942 09/25/1991       16 Citations
  • Lecithin-cholesterol acyltransferase (LCAT) catalyzes transacylation of intact cholesteryl esters. Evidence for the partial reversal of the forward LCAT reaction. (Sorci-Thomas M, Babiak J, Rudel LL) J Biol Chem 1990 Feb 15;265(5):2665-70 PMID: 2406238 02/15/1990       14 Citations
  • Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. (Sorci-Thomas M, Prack MM, Dashti N, Johnson F, Rudel LL, Williams DL) J Lipid Res 1989 Sep;30(9):1397-403 PMID: 2513367 09/01/1989       73 Citations
  • Studies on the expression of genes encoding apolipoproteins B100 and B48 and the low density lipoprotein receptor in nonhuman primates. Comparison of dietary fat and cholesterol. (Sorci-Thomas M, Wilson MD, Johnson FL, Williams DL, Rudel LL) J Biol Chem 1989 May 25;264(15):9039-45 PMID: 2722816 05/25/1989       113 Citations
  • Apolipoprotein (apo) A-I production and mRNA abundance explain plasma apoA-I and high density lipoprotein differences between two nonhuman primate species with high and low susceptibilities to diet-induced hypercholesterolemia. (Sorci-Thomas M, Prack MM, Dashti N, Johnson F, Rudel LL, Williams DL) J Biol Chem 1988 Apr 15;263(11):5183-9 PMID: 3128537 04/15/1988       54 Citations
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