Medical College of Wisconsin
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Mary Sorci Thomas PhD

Mary Sorci Thomas PhD profile photo picture


Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Research

Member of the Cancer Center
Member of the Cardiovascular Center

I am willing to mentor a junior faculty member.
I am willing to collaborate on research projects.

Research Experience

  • Atherosclerosis
  • Cholesterol, HDL
  • Macrophages
  • Stem Cells
  • Vascular Endothelial Growth Factors
  • Publications (91)

  • Regulation of Adipocyte Metabolic Homeostasis by SR-BI and PCPE2. (Knaack DA, Sorci-Thomas MG, Thomas MJ, Chen Y, Sahoo D) FASEB J 2022 May;36 Suppl 1 PMID: 35553852 SCOPUS ID: 2-s2.0-85130030599 05/14/2022    
  • Downregulation of low-density lipoprotein receptor mRNA in lymphatic endothelial cells impairs lymphatic function through changes in intracellular lipids. (Vachon L, Smaani A, Tessier N, Jean G, Demers A, Milasan A, Ardo N, Jarry S, Villeneuve L, Alikashani A, Finherty V, Ruiz M, Sorci-Thomas MG, Mayer G, Martel C) Theranostics 2022;12(3):1440-1458 PMID: 35154499 PMCID: PMC8771568 SCOPUS ID: 2-s2.0-85122672999 02/15/2022       2 Citations
  • Downregulation of low-density lipoprotein receptor mRNA in lymphatic endothelial cells impairs lymphatic function through changes in intracellular lipids (Vachon L, Smaani A, Tessier N, Jean G, Demers A, Milasan A, Ardo N, Jarry S, Villeneuve L, Alikashani A, Finherty V, Ruiz M, Sorci-Thomas MG, Mayer G, Martel C) Theranostics 2022;12(3):1440-1458 SCOPUS ID: 2-s2.0-85122672999 01/01/2022       2 Citations
  • Apolipoprotein A-I carboxy-terminal domain residues 187-243 are required for adiponectin-induced cholesterol efflux. (Hafiane A, Gianopoulos I, Sorci-Thomas MG, Daskalopoulou SS) Cell Signal 2022 Mar;91:110222 PMID: 34954016 SCOPUS ID: 2-s2.0-85121847439 12/27/2021    
  • Myeloperoxidase Inhibition Ameliorates Plaque Psoriasis in Mice. (Neu SD, Strzepa A, Martin D, Sorci-Thomas MG, Pritchard KA Jr, Dittel BN) Antioxidants (Basel) 2021 Aug 25;10(9) PMID: 34572970 PMCID: PMC8472607 SCOPUS ID: 2-s2.0-85113363981 09/29/2021       4 Citations
  • Current models of apolipoprotein A-I lipidation by adenosine triphosphate binding cassette transporter A1. (Hafiane A, Gianopoulos I, Sorci-Thomas MG, Daskalopoulou SS) Curr Opin Lipidol 2022 Apr 01;33(2):139-145 PMID: 34581311 SCOPUS ID: 2-s2.0-85125682549 09/29/2021       2 Citations
  • Pcpe2, a Novel Extracellular Matrix Protein, Regulates Adipocyte SR-BI-Mediated High-Density Lipoprotein Uptake. (Xu H, Thomas MJ, Kaul S, Kallinger R, Ouweneel AB, Maruko E, Oussaada SM, Jongejan A, Cense HA, Nieuwdorp M, Serlie MJ, Goldberg IJ, Civelek M, Parks BW, Lusis AJ, Knaack D, Schill RL, May SC, Reho JJ, Grobe JL, Gantner B, Sahoo D, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2021 Nov;41(11):2708-2725 PMID: 34551590 PMCID: PMC8551036 SCOPUS ID: 2-s2.0-85118592107 09/24/2021       2 Citations
  • Myeloperoxidase inhibition ameliorates plaque psoriasis in mice (Neu SD, Strzepa A, Martin D, Sorci-Thomas MG, Pritchard KA, Dittel BN) Antioxidants September 2021;10(9) SCOPUS ID: 2-s2.0-85113363981 09/01/2021       4 Citations
  • Enterically derived high-density lipoprotein restrains liver injury through the portal vein. (Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ) Science 2021 Jul 23;373(6553) PMID: 34437091 PMCID: PMC8478306 SCOPUS ID: 2-s2.0-85111031761 08/27/2021       45 Citations
  • Enterically derived high-density lipoprotein restrains liver injury through the portal vein (Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ) Science 23 July 2021;373(6553) SCOPUS ID: 2-s2.0-85111031761 07/23/2021       45 Citations
  • The ins and outs of lipid rafts: functions in intracellular cholesterol homeostasis, microparticles, and cell membranes: Thematic Review Series: Biology of Lipid Rafts. (Ouweneel AB, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2020 May;61(5):676-686 PMID: 33715815 PMCID: PMC7193959 SCOPUS ID: 2-s2.0-85084961109 03/16/2021       39 Citations
  • Endothelial Rap1 (Ras-Association Proximate 1) Restricts Inflammatory Signaling to Protect From the Progression of Atherosclerosis. (Singh B, Kosuru R, Lakshmikanthan S, Sorci-Thomas MG, Zhang DX, Sparapani R, Vasquez-Vivar J, Chrzanowska M) Arterioscler Thromb Vasc Biol 2021 Feb;41(2):638-650 PMID: 33267664 PMCID: PMC8105264 SCOPUS ID: 2-s2.0-85104181830 12/04/2020       11 Citations
  • Linking Lipid-Related Transcription and Cardiovascular Disease Through GWAS. (Thomas MJ, Sorci-Thomas MG) Circ Res 2020 Nov 06;127(11):1362-1364 PMID: 33151796 PMCID: PMC7653958 SCOPUS ID: 2-s2.0-85095758046 11/06/2020       1 Citation
  • Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism. (Li Z, Votava JA, Zajac GJM, Nguyen JN, Leyva Jaimes FB, Ly SM, Brinkman JA, De Giorgi M, Kaul S, Green CL, St Clair SL, Belisle SL, Rios JM, Nelson DW, Sorci-Thomas MG, Lagor WR, Lamming DW, Eric Yen CL, Parks BW) Cell Metab 2020 Apr 07;31(4):741-754.e5 PMID: 32197071 PMCID: PMC7184639 SCOPUS ID: 2-s2.0-85082744030 03/21/2020       16 Citations
  • Proceedings of the Ninth HDL (High-Density Lipoprotein) Workshop: Focus on Cardiovascular Disease. (Rodriguez A, Trigatti BL, Mineo C, Knaack D, Wilkins JT, Sahoo D, Asztalos BF, Mora S, Cuchel M, Pownall HJ, Rosales C, Bernatchez P, Ribeiro Martins da Silva A, Getz GS, Barber JL, Shearer GC, Zivkovic AM, Tietge UJF, Sacks FM, Connelly MA, Oda MN, Davidson WS, Sorci-Thomas MG, Vaisar T, Ruotolo G, Vickers KC, Martel C) Arterioscler Thromb Vasc Biol 2019 Dec;39(12):2457-2467 PMID: 31597448 PMCID: PMC6937204 SCOPUS ID: 2-s2.0-85075813183 10/11/2019       7 Citations
  • Recombinant LCAT (Lecithin:Cholesterol Acyltransferase) Rescues Defective HDL (High-Density Lipoprotein)-Mediated Endothelial Protection in Acute Coronary Syndrome. (Ossoli A, Simonelli S, Varrenti M, Morici N, Oliva F, Stucchi M, Gomaraschi M, Strazzella A, Arnaboldi L, Thomas MJ, Sorci-Thomas MG, Corsini A, Veglia F, Franceschini G, Karathanasis SK, Calabresi L) Arterioscler Thromb Vasc Biol 2019 May;39(5):915-924 PMID: 30894011 SCOPUS ID: 2-s2.0-85065216772 03/22/2019       28 Citations
  • Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (Huang LH, Zinselmeyer BH, Chang CH, Saunders BT, Elvington A, Baba O, Broekelmann TJ, Qi L, Rueve JS, Swartz MA, Kim BS, Mecham RP, Wiig H, Thomas MJ, Sorci-Thomas MG, Randolph GJ) Cell Metab 2019 Feb 05;29(2):475-487.e7 PMID: 30415924 PMCID: PMC6365189 SCOPUS ID: 2-s2.0-85060717940 11/13/2018       28 Citations
  • Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. (Gaddis DE, Padgett LE, Wu R, McSkimming C, Romines V, Taylor AM, McNamara CA, Kronenberg M, Crotty S, Thomas MJ, Sorci-Thomas MG, Hedrick CC) Nat Commun 2018 Mar 15;9(1):1095 PMID: 29545616 PMCID: PMC5854619 SCOPUS ID: 2-s2.0-85044288848 03/17/2018       89 Citations
  • High-Density Lipoprotein Functionality as a New Pharmacological Target on Cardiovascular Disease: Unifying Mechanism That Explains High-Density Lipoprotein Protection Toward the Progression of Atherosclerosis. (Favari E, Thomas MJ, Sorci-Thomas MG) J Cardiovasc Pharmacol 2018 Jun;71(6):325-331 PMID: 29528874 SCOPUS ID: 2-s2.0-85051788295 03/13/2018       27 Citations
  • A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state. (Melchior JT, Walker RG, Cooke AL, Morris J, Castleberry M, Thompson TB, Jones MK, Song HD, Rye KA, Oda MN, Sorci-Thomas MG, Thomas MJ, Heinecke JW, Mei X, Atkinson D, Segrest JP, Lund-Katz S, Phillips MC, Davidson WS) Nat Struct Mol Biol 2017 Dec;24(12):1093-1099 PMID: 29131142 PMCID: PMC5749415 SCOPUS ID: 2-s2.0-85039561595 11/14/2017       36 Citations
  • Apolipoprotein A-I Modulates Atherosclerosis Through Lymphatic Vessel-Dependent Mechanisms in Mice. (Milasan A, Jean G, Dallaire F, Tardif JC, Merhi Y, Sorci-Thomas M, Martel C) J Am Heart Assoc 2017 Sep 22;6(9) PMID: 28939717 PMCID: PMC5634311 SCOPUS ID: 2-s2.0-85047906536 09/25/2017       26 Citations
  • Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood. (Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ) Circ Res 2017 Sep 01;121(6):662-676 PMID: 28696252 PMCID: PMC5718914 SCOPUS ID: 2-s2.0-85023200643 07/12/2017       25 Citations
  • Anti-inflammatory liaisons: T regulatory cells and HDL. (Sorci-Thomas MG, Thomas MJ) J Lipid Res 2017 Aug;58(8):1491-1492 PMID: 28630261 PMCID: PMC5538272 SCOPUS ID: 2-s2.0-85026671098 06/21/2017       1 Citation
  • AIBP, NAXE, and Angiogenesis: What's in a Name? (Sorci-Thomas MG, Thomas MJ) Circ Res 2017 May 26;120(11):1690-1691 PMID: 28546345 PMCID: PMC5497770 SCOPUS ID: 2-s2.0-85019757650 05/27/2017       6 Citations
  • Rediscovering scavenger receptor type BI: surprising new roles for the HDL receptor. (Hoekstra M, Sorci-Thomas M) Curr Opin Lipidol 2017 Jun;28(3):255-260 PMID: 28301373 PMCID: PMC5523812 SCOPUS ID: 2-s2.0-85015644706 03/17/2017       15 Citations
  • S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. (Lee MH, Appleton KM, El-Shewy HM, Sorci-Thomas MG, Thomas MJ, Lopes-Virella MF, Luttrell LM, Hammad SM, Klein RL) J Lipid Res 2017 Feb;58(2):325-338 PMID: 27881715 PMCID: PMC5282949 SCOPUS ID: 2-s2.0-85011295067 11/25/2016       29 Citations
  • Lipid-Free Apolipoprotein A-I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio. (Kaul S, Xu H, Zabalawi M, Maruko E, Fulp BE, Bluemn T, Brzoza-Lewis KL, Gerelus M, Weerasekera R, Kallinger R, James R, Zhang YS, Thomas MJ, Sorci-Thomas MG) J Am Heart Assoc 2016 Nov 07;5(11) PMID: 27821400 PMCID: PMC5210328 SCOPUS ID: 2-s2.0-85032586305 11/09/2016       17 Citations
  • High-Density Lipoprotein Biogenesis: Defining the Domains Involved in Human Apolipoprotein A-I Lipidation. (Pollard RD, Fulp B, Sorci-Thomas MG, Thomas MJ) Biochemistry 2016 Sep 06;55(35):4971-81 PMID: 27501467 PMCID: PMC5356376 SCOPUS ID: 2-s2.0-84985914329 08/09/2016       13 Citations
  • Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. (Cheng HY, Gaddis DE, Wu R, McSkimming C, Haynes LD, Taylor AM, McNamara CA, Sorci-Thomas M, Hedrick CC) J Clin Invest 2016 Sep 01;126(9):3236-46 PMID: 27482882 PMCID: PMC5004951 SCOPUS ID: 2-s2.0-84987849199 08/03/2016       45 Citations
  • Microdomains, Inflammation, and Atherosclerosis. (Sorci-Thomas MG, Thomas MJ) Circ Res 2016 Feb 19;118(4):679-91 PMID: 26892966 PMCID: PMC5291489 SCOPUS ID: 2-s2.0-84959058398 02/20/2016       112 Citations
  • Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses. (Navratil AR, Vozenilek AE, Cardelli JA, Green JM, Thomas MJ, Sorci-Thomas MG, Orr AW, Woolard MD) Atherosclerosis 2015 Oct;242(2):424-32 PMID: 26288136 PMCID: PMC4712446 SCOPUS ID: 2-s2.0-84939606543 08/20/2015       13 Citations
  • What does procollagen C-endopeptidase enhancer protein 2 have to do with HDL-cholesteryl ester uptake? Or how I learned to stop worrying and love reverse cholesterol transport? (Sorci-Thomas MG, Pollard RD, Thomas MJ) Curr Opin Lipidol 2015 Oct;26(5):420-5 PMID: 26218419 PMCID: PMC4564020 SCOPUS ID: 2-s2.0-84944345774 07/29/2015       10 Citations
  • SAA: a link between cholesterol efflux capacity and inflammation? (Thomas MJ, Sorci-Thomas MG) J Lipid Res 2015 Aug;56(8):1383-5 PMID: 26078331 PMCID: PMC4513981 SCOPUS ID: 2-s2.0-84940521694 06/17/2015       9 Citations
  • Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice. (Liu J, Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Sorci-Thomas M, Cassis LA, Daugherty A) Arterioscler Thromb Vasc Biol 2015 Aug;35(8):1826-34 PMID: 26044581 PMCID: PMC4514578 SCOPUS ID: 2-s2.0-84938062520 06/06/2015       33 Citations
  • Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake. (Pollard RD, Blesso CN, Zabalawi M, Fulp B, Gerelus M, Zhu X, Lyons EW, Nuradin N, Francone OL, Li XA, Sahoo D, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2015 Jun 19;290(25):15496-15511 PMID: 25947382 PMCID: PMC4505464 SCOPUS ID: 2-s2.0-84939623747 05/08/2015       23 Citations
  • Acrolein impairs the cholesterol transport functions of high density lipoproteins. (Chadwick AC, Holme RL, Chen Y, Thomas MJ, Sorci-Thomas MG, Silverstein RL, Pritchard KA Jr, Sahoo D) PLoS One 2015;10(4):e0123138 PMID: 25849485 PMCID: PMC4388475 SCOPUS ID: 2-s2.0-84927672521 04/08/2015       30 Citations
  • Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL. (Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S) J Lipid Res 2015 Mar;56(3):635-643 PMID: 25593328 PMCID: PMC4340310 SCOPUS ID: 2-s2.0-84925238577 01/17/2015       24 Citations
  • Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression. (Gao M, Zhao D, Schouteden S, Sorci-Thomas MG, Van Veldhoven PP, Eggermont K, Liu G, Verfaillie CM, Feng Y) Arterioscler Thromb Vasc Biol 2014 Sep;34(9):1900-9 PMID: 24969774 PMCID: PMC4140992 SCOPUS ID: 2-s2.0-84906940408 06/28/2014       48 Citations
  • Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. (Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS) J Biol Chem 2014 Jan 31;289(5):2801-14 PMID: 24318881 PMCID: PMC3908412 SCOPUS ID: 2-s2.0-84893431254 12/10/2013       56 Citations
  • The conformation of lipid-free human apolipoprotein A-I in solution. (Pollard RD, Fulp B, Samuel MP, Sorci-Thomas MG, Thomas MJ) Biochemistry 2013 Dec 31;52(52):9470-81 PMID: 24308268 PMCID: PMC3926756 SCOPUS ID: 2-s2.0-84891510210 12/07/2013       28 Citations
  • Why targeting HDL should work as a therapeutic tool, but has not. (Sorci-Thomas MG, Thomas MJ) J Cardiovasc Pharmacol 2013 Sep;62(3):239-46 PMID: 23743767 PMCID: PMC3772973 SCOPUS ID: 2-s2.0-84884671413 06/08/2013       28 Citations
  • Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. (Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ) J Clin Invest 2013 Apr;123(4):1571-9 PMID: 23524964 PMCID: PMC3613904 SCOPUS ID: 2-s2.0-84875873877 03/26/2013       222 Citations
  • High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. (Sorci-Thomas MG, Thomas MJ) Arterioscler Thromb Vasc Biol 2012 Nov;32(11):2561-5 PMID: 23077142 PMCID: PMC3793253 SCOPUS ID: 2-s2.0-84871865547 10/19/2012       77 Citations
  • Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers. (Sorci-Thomas MG, Owen JS, Fulp B, Bhat S, Zhu X, Parks JS, Shah D, Jerome WG, Gerelus M, Zabalawi M, Thomas MJ) J Lipid Res 2012 Sep;53(9):1890-909 PMID: 22750655 PMCID: PMC3413229 SCOPUS ID: 2-s2.0-84864851111 07/04/2012       95 Citations
  • Dysfunctional HDL containing L159R ApoA-I leads to exacerbation of atherosclerosis in hyperlipidemic mice. (Sorci-Thomas MG, Zabalawi M, Bharadwaj MS, Wilhelm AJ, Owen JS, Asztalos BF, Bhat S, Thomas MJ) Biochim Biophys Acta 2012 Mar;1821(3):502-12 PMID: 21944998 PMCID: PMC3690280 SCOPUS ID: 2-s2.0-84857635187 09/29/2011       16 Citations
  • Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. (Potteaux S, Gautier EL, Hutchison SB, van Rooijen N, Rader DJ, Thomas MJ, Sorci-Thomas MG, Randolph GJ) J Clin Invest 2011 May;121(5):2025-36 PMID: 21505265 PMCID: PMC3083793 SCOPUS ID: 2-s2.0-79955503060 04/21/2011       267 Citations
  • Apolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice. (Wilhelm AJ, Zabalawi M, Owen JS, Shah D, Grayson JM, Major AS, Bhat S, Gibbs DP Jr, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2010 Nov 12;285(46):36158-69 PMID: 20833724 PMCID: PMC2975238 SCOPUS ID: 2-s2.0-77958478114 09/14/2010       99 Citations
  • Conformation of dimeric apolipoprotein A-I milano on recombinant lipoprotein particles. (Bhat S, Sorci-Thomas MG, Calabresi L, Samuel MP, Thomas MJ) Biochemistry 2010 Jun 29;49(25):5213-24 PMID: 20524691 PMCID: PMC2946800 SCOPUS ID: 2-s2.0-77953891139 06/08/2010       16 Citations
  • Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70 PMID: 20498409 PMCID: PMC2918439 SCOPUS ID: 2-s2.0-77956861083 05/26/2010       63 Citations
  • Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. (Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2009 Jun;29(6):843-9 PMID: 19286630 PMCID: PMC2761013 SCOPUS ID: 2-s2.0-66349139424 03/17/2009       99 Citations
  • Activation of lecithin:cholesterol acyltransferase by HDL ApoA-I central helices. (Sorci-Thomas MG, Bhat S, Thomas MJ) Clin Lipidol 2009 Feb;4(1):113-124 PMID: 20582235 PMCID: PMC2891274 SCOPUS ID: 2-s2.0-67149105628 02/01/2009       55 Citations
  • Three-dimensional models of HDL apoA-I: implications for its assembly and function. (Thomas MJ, Bhat S, Sorci-Thomas MG) J Lipid Res 2008 Sep;49(9):1875-83 PMID: 18515783 PMCID: PMC2515525 SCOPUS ID: 2-s2.0-53149092105 06/03/2008       90 Citations
  • Conformational adaptation of apolipoprotein A-I to discretely sized phospholipid complexes. (Bhat S, Sorci-Thomas MG, Tuladhar R, Samuel MP, Thomas MJ) Biochemistry 2007 Jul 03;46(26):7811-21 PMID: 17563120 PMCID: PMC2553278 SCOPUS ID: 2-s2.0-34347356570 06/15/2007       64 Citations
  • Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin. (Owen JS, Bharadwaj MS, Thomas MJ, Bhat S, Samuel MP, Sorci-Thomas MG) J Lipid Res 2007 Jan;48(1):226-34 PMID: 17071967 SCOPUS ID: 2-s2.0-33845972961 10/31/2006       10 Citations
  • Inflammation and skin cholesterol in LDLr-/-, apoA-I-/- mice: link between cholesterol homeostasis and self-tolerance? (Zabalawi M, Bharadwaj M, Horton H, Cline M, Willingham M, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2007 Jan;48(1):52-65 PMID: 17071966 SCOPUS ID: 2-s2.0-33846007994 10/31/2006       37 Citations
  • The use of chemical cross-linking and mass spectrometry to elucidate the tertiary conformation of lipid-bound apolipoprotein A-I. (Thomas MJ, Bhat S, Sorci-Thomas MG) Curr Opin Lipidol 2006 Jun;17(3):214-20 PMID: 16680024 SCOPUS ID: 2-s2.0-33646858367 05/09/2006       21 Citations
  • Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. (Ou J, Wang J, Xu H, Ou Z, Sorci-Thomas MG, Jones DW, Signorino P, Densmore JC, Kaul S, Oldham KT, Pritchard KA Jr) Circ Res 2005 Nov 25;97(11):1190-7 PMID: 16224061 PMCID: PMC1480357 SCOPUS ID: 2-s2.0-33644675579 10/15/2005       108 Citations
  • Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry. (Bhat S, Sorci-Thomas MG, Alexander ET, Samuel MP, Thomas MJ) J Biol Chem 2005 Sep 23;280(38):33015-25 PMID: 15972827 SCOPUS ID: 2-s2.0-25444491569 06/24/2005       87 Citations
  • Apolipoprotein A-I helix 6 negatively charged residues attenuate lecithin-cholesterol acyltransferase (LCAT) reactivity. (Alexander ET, Bhat S, Thomas MJ, Weinberg RB, Cook VR, Bharadwaj MS, Sorci-Thomas M) Biochemistry 2005 Apr 12;44(14):5409-19 PMID: 15807534 SCOPUS ID: 2-s2.0-16844370698 04/06/2005       32 Citations
  • Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions. (Bhat S, Zabalawi M, Willingham MC, Shelness GS, Thomas MJ, Sorci-Thomas MG) J Lipid Res 2004 Jul;45(7):1207-20 PMID: 15060083 SCOPUS ID: 2-s2.0-3042651483 04/03/2004       10 Citations
  • Induction of fatal inflammation in LDL receptor and ApoA-I double-knockout mice fed dietary fat and cholesterol. (Zabalawi M, Bhat S, Loughlin T, Thomas MJ, Alexander E, Cline M, Bullock B, Willingham M, Sorci-Thomas MG) Am J Pathol 2003 Sep;163(3):1201-13 PMID: 12937162 PMCID: PMC1868257 SCOPUS ID: 2-s2.0-0041924007 08/26/2003       55 Citations
  • Alpha-tocopherol protects against diet induced atherosclerosis in New Zealand white rabbits. (Schwenke DC, Rudel LL, Sorci-Thomas MG, Thomas MJ) J Lipid Res 2002 Nov;43(11):1927-38 PMID: 12401892 SCOPUS ID: 2-s2.0-0036847082 10/29/2002       31 Citations
  • ApoA-I structure on discs and spheres. Variable helix registry and conformational states. (Li HH, Lyles DS, Pan W, Alexander E, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2002 Oct 18;277(42):39093-101 PMID: 12167653 SCOPUS ID: 2-s2.0-0037131260 08/09/2002       67 Citations
  • The effects of altered apolipoprotein A-I structure on plasma HDL concentration. (Sorci-Thomas MG, Thomas MJ) Trends Cardiovasc Med 2002 Apr;12(3):121-8 PMID: 12007737 SCOPUS ID: 2-s2.0-0036234218 05/15/2002       169 Citations
  • Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. (Reschly EJ, Sorci-Thomas MG, Davidson WS, Meredith SC, Reardon CA, Getz GS) J Biol Chem 2002 Mar 22;277(12):9645-54 PMID: 11744719 SCOPUS ID: 2-s2.0-0037155808 12/18/2001       37 Citations
  • Preparation and incorporation of probe-labeled apoA-I for fluorescence resonance energy transfer studies of rHDL. (Li HH, Thomas MJ, Pan W, Alexander E, Samuel M, Sorci-Thomas MG) J Lipid Res 2001 Dec;42(12):2084-91 PMID: 11734582 SCOPUS ID: 2-s2.0-0035664834 12/06/2001       19 Citations
  • Isoprostane levels in lipids extracted from atherosclerotic arteries of nonhuman primates. (Thomas MJ, Chen Q, Sorci-Thomas MG, Rudel LL) Free Radic Biol Med 2001 Jun 15;30(12):1337-46 PMID: 11390178 SCOPUS ID: 2-s2.0-0035877154 06/08/2001       11 Citations
  • Is the oxidation of high-density lipoprotein lipids different than the oxidation of low-density lipoprotein lipids? (Thomas MJ, Chen Q, Zabalawi M, Anderson R, Wilson M, Weinberg R, Sorci-Thomas MG, Rudel LL) Biochemistry 2001 Feb 13;40(6):1719-24 PMID: 11327832 SCOPUS ID: 2-s2.0-0035852830 05/01/2001       18 Citations
  • Structural determination of lipid-bound ApoA-I using fluorescence resonance energy transfer. (Li H, Lyles DS, Thomas MJ, Pan W, Sorci-Thomas MG) J Biol Chem 2000 Nov 24;275(47):37048-54 PMID: 10956648 SCOPUS ID: 2-s2.0-0034711217 08/25/2000       84 Citations
  • Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice. (Sorci-Thomas MG, Thomas M, Curtiss L, Landrum M) J Biol Chem 2000 Apr 21;275(16):12156-63 PMID: 10766851 SCOPUS ID: 2-s2.0-0034697316 04/15/2000       43 Citations
  • The hydrophobic face orientation of apolipoprotein A-I amphipathic helix domain 143-164 regulates lecithin:cholesterol acyltransferase activation. (Sorci-Thomas MG, Curtiss L, Parks JS, Thomas MJ, Kearns MW, Landrum M) J Biol Chem 1998 May 08;273(19):11776-82 PMID: 9565601 SCOPUS ID: 2-s2.0-0032496221 06/13/1998       72 Citations
  • Sex steroids increase cholesterol 7alpha-hydroxylase mRNA in nonhuman primates. (Colvin PL Jr, Wagner JD, Adams MR, Sorci-Thomas MG) Metabolism 1998 Apr;47(4):391-5 PMID: 9550534 SCOPUS ID: 2-s2.0-0004575076 04/29/1998       18 Citations
  • Alteration in apolipoprotein A-I 22-mer repeat order results in a decrease in lecithin:cholesterol acyltransferase reactivity. (Sorci-Thomas MG, Curtiss L, Parks JS, Thomas MJ, Kearns MW) J Biol Chem 1997 Mar 14;272(11):7278-84 PMID: 9054424 SCOPUS ID: 2-s2.0-0030906053 03/14/1997       57 Citations
  • High level secretion of wild-type and mutant forms of human proapoA-I using baculovirus-mediated Sf-9 cell expression. (Sorci-Thomas MG, Parks JS, Kearns MW, Pate GN, Zhang C, Thomas MJ) J Lipid Res 1996 Mar;37(3):673-83 PMID: 8728328 SCOPUS ID: 2-s2.0-0029916540 03/01/1996       43 Citations
  • Glycosylation structure and enzyme activity of lecithin:cholesterol acyltransferase from human plasma, HepG2 cells, and baculoviral and Chinese hamster ovary cell expression systems. (Miller KR, Wang J, Sorci-Thomas M, Anderson RA, Parks JS) J Lipid Res 1996 Mar;37(3):551-61 PMID: 8728318 SCOPUS ID: 2-s2.0-0029976437 03/01/1996       27 Citations
  • Cortisol up-regulates corticotropin releasing factor gene expression in the fetal ovine brainstem at 0.70 gestation. (Keiger CJ, O'Steen WK, Brewer G, Sorci-Thomas M, Zehnder TJ, Rose JC) Brain Res Mol Brain Res 1995 Aug;32(1):75-81 PMID: 7494465 SCOPUS ID: 2-s2.0-0029009462 08/01/1995       6 Citations
  • Species-specific polymorphism in the promoter of the apolipoprotein A-I gene: restoration of human transcriptional efficiency by substitution at positions -189, -144 and -48 bp. (Sorci-Thomas M, Kearns MW) Biochim Biophys Acta 1995 Jun 06;1256(3):387-95 PMID: 7786904 SCOPUS ID: 2-s2.0-0029032854 06/06/1995       2 Citations
  • Estrogen modulates the inducible expression of platelet-derived growth factor mRNA by monocyte/macrophages. (Shanker G, Sorci-Thomas M, Adams MR) Life Sci 1995;56(7):499-507 PMID: 7869830 SCOPUS ID: 2-s2.0-0028859592 01/01/1995       42 Citations
  • Estrogen modulates the expression of tumor necrosis factor alpha mRNA in phorbol ester-stimulated human monocytic THP-1 cells. (Shanker G, Sorci-Thomas M, Adams MR) Lymphokine Cytokine Res 1994 Dec;13(6):377-82 PMID: 7703311 SCOPUS ID: 2-s2.0-0028582090 12/01/1994       67 Citations
  • Corticotropin releasing factor mRNA and peptide levels are differentially regulated in the developing ovine brain. (Keiger CJ, O'Steen WK, Brewer G, Sorci-Thomas M, Zehnder TJ, Rose JC) Brain Res Mol Brain Res 1994 Nov;27(1):103-10 PMID: 7877440 SCOPUS ID: 2-s2.0-0027985727 11/01/1994       3 Citations
  • The inducible expression of THP-1 cell interleukin-1 mRNA: effects of estrogen on differential response to phorbol ester and lipopolysaccharide. (Shanker G, Sorci-Thomas M, Register TC, Adams MR) Lymphokine Cytokine Res 1994 Feb;13(1):1-7 PMID: 8186319 SCOPUS ID: 2-s2.0-0028294994 02/01/1994       19 Citations
  • Cytokines decrease apolipoprotein accumulation in medium from Hep G2 cells. (Ettinger WH, Varma VK, Sorci-Thomas M, Parks JS, Sigmon RC, Smith TK, Verdery RB) Arterioscler Thromb 1994 Jan;14(1):8-13 PMID: 8274481 SCOPUS ID: 2-s2.0-0028047714 01/01/1994       159 Citations
  • Oral contraceptives decrease hepatic cholesterol independent of the LDL receptor in nonhuman primates. (Colvin PL Jr, Wagner JD, Heuser MD, Sorci-Thomas MG) Arterioscler Thromb 1993 Nov;13(11):1645-9 PMID: 8218105 SCOPUS ID: 2-s2.0-0027425634 11/01/1993       5 Citations
  • Apolipoprotein A-I domains involved in lecithin-cholesterol acyltransferase activation. Structure:function relationships. (Sorci-Thomas M, Kearns MW, Lee JP) J Biol Chem 1993 Oct 05;268(28):21403-9 PMID: 8407982 SCOPUS ID: 2-s2.0-0027384540 10/05/1993       118 Citations
  • Dexamethasone increases apolipoprotein A-I concentrations in medium and apolipoprotein A-I mRNA abundance from Hep G2 cells. (Varma VK, Smith TK, Sorci-Thomas M, Ettinger WH Jr) Metabolism 1992 Oct;41(10):1075-80 PMID: 1328818 SCOPUS ID: 2-s2.0-0026657442 10/11/1992       18 Citations
  • HepG2 cell LDL receptor activity and the accumulation of apolipoprotein B and E in response to docosahexaenoic acid and cholesterol. (Sorci-Thomas M, Hendricks CL, Kearns MW) J Lipid Res 1992 Aug;33(8):1147-56 PMID: 1431595 SCOPUS ID: 2-s2.0-0026706709 08/01/1992       20 Citations
  • Transcriptional regulation of the apolipoprotein A-I gene. Species-specific expression correlates with rates of gene transcription. (Sorci-Thomas M, Kearns MW) J Biol Chem 1991 Sep 25;266(27):18045-50 PMID: 1917942 SCOPUS ID: 2-s2.0-0025950961 09/25/1991       16 Citations
  • Lecithin-cholesterol acyltransferase (LCAT) catalyzes transacylation of intact cholesteryl esters. Evidence for the partial reversal of the forward LCAT reaction. (Sorci-Thomas M, Babiak J, Rudel LL) J Biol Chem 1990 Feb 15;265(5):2665-70 PMID: 2406238 SCOPUS ID: 2-s2.0-0025347085 02/15/1990       14 Citations
  • Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. (Sorci-Thomas M, Prack MM, Dashti N, Johnson F, Rudel LL, Williams DL) J Lipid Res 1989 Sep;30(9):1397-403 PMID: 2513367 SCOPUS ID: 2-s2.0-0024425420 09/01/1989       76 Citations
  • Studies on the expression of genes encoding apolipoproteins B100 and B48 and the low density lipoprotein receptor in nonhuman primates. Comparison of dietary fat and cholesterol. (Sorci-Thomas M, Wilson MD, Johnson FL, Williams DL, Rudel LL) J Biol Chem 1989 May 25;264(15):9039-45 PMID: 2722816 SCOPUS ID: 2-s2.0-0024403463 05/25/1989       115 Citations
  • Apolipoprotein (apo) A-I production and mRNA abundance explain plasma apoA-I and high density lipoprotein differences between two nonhuman primate species with high and low susceptibilities to diet-induced hypercholesterolemia. (Sorci-Thomas M, Prack MM, Dashti N, Johnson F, Rudel LL, Williams DL) J Biol Chem 1988 Apr 15;263(11):5183-9 PMID: 3128537 SCOPUS ID: 2-s2.0-0023926909 04/15/1988       55 Citations
  • Last update: 10/17/2022