Ranjan K. Dash PhD
Professor
Institution: Medical College of Wisconsin
Department: Biomedical Engineering
Program: Biomedical Engineering Program
Member of the Cardiovascular Center
Send Message
Request Meeting
Research Areas of Interest
BioengineeringCardiovascular Physiological PhenomenaCell Physiological PhenomenaComputational BiologyMetabolismReactive Oxygen SpeciesPublications (114)
Effects of N2 O elimination on the elimination of second gases in a two-step mathematical model of heterogeneous gas exchange. (Korman B, Dash RK, Peyton PJ) Physiol Rep 2023 Nov;11(21):e15822 PMID: 37923389 PMCID: PMC10624564 SCOPUS ID: 2-s2.0-85175992343 11/06/2023 Metabolic Responses of Normal Rat Kidneys to a High Salt Intake. (Shimada S, Hoffmann BR, Yang C, Kurth T, Greene AS, Liang M, Dash RK, Cowley AW Jr) Function (Oxf) 2023;4(5):zqad031 PMID: 37575482 PMCID: PMC10413938 SCOPUS ID: 2-s2.0-85168069622 08/14/2023 1 CitationComputational Modeling of Substrate-Dependent Mitochondrial Respiration and Bioenergetics in the Heart and Kidney Cortex and Outer Medulla. (Sadri S, Zhang X, Audi SH, Cowley AW Jr, Dash RK) Function (Oxf) 2023;4(5):zqad038 PMID: 37575476 PMCID: PMC10413947 SCOPUS ID: 2-s2.0-85168064544 08/14/2023 Effects of ROS pathway inhibitors and NADH and FADH2 linked substrates on mitochondrial bioenergetics and ROS emission in the heart and kidney cortex and outer medulla. (Sadri S, Tomar N, Yang C, Audi SH, Cowley AW Jr, Dash RK) Arch Biochem Biophys 2023 Aug;744:109690 PMID: 37429534 PMCID: PMC10528392 SCOPUS ID: 2-s2.0-85165963858 07/11/2023 Simulating the Evolution of Signaling Signatures during CART-Cell - Tumor Cell Interactions. (Shah V, Womack J, Zamora AE, Terhune SS, Dash RK) ArXiv 2023 Feb 08 PMID: 36798455 PMCID: PMC9934731 02/18/2023 Metabolic responses of normal rat kidneys to a high salt intake. (Shimada S, Hoffmann BR, Yang C, Kurth T, Greene AS, Liang M, Dash RK, Cowley AW) bioRxiv 2023 Jan 31 PMID: 36711564 PMCID: PMC9882299 01/31/2023 Computational modeling of protracted HCMV replication using genome substrates and protein temporal profiles. (Monti CE, Mokry RL, Schumacher ML, Dash RK, Terhune SS) Proc Natl Acad Sci U S A 2022 Aug 30;119(35):e2201787119 PMID: 35994667 PMCID: PMC9437303 SCOPUS ID: 2-s2.0-85136192098 08/23/2022 Fluorescein clearance kinetics in blood and bile indicates hepatic ischemia-reperfusion injury in rats. (Kim J, Yang Y, Hong SK, Zielonka J, Dash RK, Audi SH, Kumar SN, Joshi A, Zimmerman MA, Hong JC) Am J Physiol Gastrointest Liver Physiol 2022 Aug 01;323(2):G126-G133 PMID: 35700191 SCOPUS ID: 2-s2.0-85134761396 06/15/2022 Assessment of Mitochondrial Respiratory Function in Isolated Nephron Segments of Dahl SS Rats in Salt Induced Hypertension. (Yang C, Zheleznova NN, Dash RK, Cowley AW Jr) FASEB J 2022 May;36 Suppl 1 PMID: 35557199 SCOPUS ID: 2-s2.0-85130067197 05/14/2022 Reverse Electron Transfer is a More Dominant Source of Mitochondrial ROS Production in the Heart and Kidney Outer Medulla than in the Kidney Cortex. (Sadri S, Tomar N, Zhang X, Yang C, Audi SH, Cowley AW Jr, Dash RK) FASEB J 2022 May;36 Suppl 1 PMID: 35556376 SCOPUS ID: 2-s2.0-85130038508 05/14/2022 Substrate-Dependent Differential Regulation of Mitochondrial Bioenergetics and ROS emission in the Heart and Kidney Cortex and Outer Medulla. (Tomar N, Sadri S, Zhang X, Kandel S, Yang C, Audi S, Cowley AW Jr, Dash RK) FASEB J 2022 May;36 Suppl 1 PMID: 35555208 SCOPUS ID: 2-s2.0-85130062178 05/14/2022 Changes in Oxygen Consumption and Metabolomic Profiles in the Kidney of Sprague-Dawley Rat fed a High-Salt Diet. (Shimada S, Hoffmann B, Greene A, Liang M, Dash RK, Cowley AW Jr) FASEB J 2022 May;36 Suppl 1 PMID: 35555025 SCOPUS ID: 2-s2.0-85130063536 05/14/2022 Computational Modeling of Substrate-Dependent Differential Regulation of Mitochondrial Bioenergetics in the Heart and Kidney Cortex and Outer Medulla. (Zhang X, Tomar N, Sadri S, Audi S, Cowley AW Jr, Dash RK) FASEB J 2022 May;36 Suppl 1 PMID: 35551713 SCOPUS ID: 2-s2.0-85130632203 05/14/2022 Metabolomic Kidney Input and Output Analyses in Salt-Sensitive Hypertension (Hoffmann BR, Shimada S, Greene AS, Liang M, Dash R, Cowley A) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1 May 2022;36 PMID: 35555364 SCOPUS ID: 2-s2.0-85130030519 05/01/2022 Depolarized Mitochondrial Membrane Potential and Protection with Duroquinone in Isolated Perfused Lungs from Rats Exposed to Hyperoxia (Audi S, Ganesh S, Taheri P, Zhang X, Dash R, Clough A, Jacobs E) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1 May 2022;36 PMID: 35552019 SCOPUS ID: 2-s2.0-85130635620 05/01/2022 Substrate- and Calcium-Dependent Differential Regulation of Mitochondrial Oxidative Phosphorylation and Energy Production in the Heart and Kidney. (Zhang X, Tomar N, Kandel SM, Audi SH, Cowley AW Jr, Dash RK) Cells 2021 Dec 31;11(1) PMID: 35011693 PMCID: PMC8750792 SCOPUS ID: 2-s2.0-85122006134 01/12/2022 6 CitationsDepolarized mitochondrial membrane potential and protection with duroquinone in isolated perfused lungs from rats exposed to hyperoxia. (Audi SH, Ganesh S, Taheri P, Zhang X, Dash RK, Clough AV, Jacobs ER) J Appl Physiol (1985) 2022 Feb 01;132(2):346-356 PMID: 34941441 PMCID: PMC8816614 SCOPUS ID: 2-s2.0-85124056241 12/24/2021 4 CitationsCrosstalk between Plk1, p53, cell cycle, and G2/M DNA damage checkpoint regulation in cancer: computational modeling and analysis. (Jung Y, Kraikivski P, Shafiekhani S, Terhune SS, Dash RK) NPJ Syst Biol Appl 2021 Dec 09;7(1):46 PMID: 34887439 PMCID: PMC8660825 SCOPUS ID: 2-s2.0-85121043614 12/11/2021 19 CitationsSubstrate-dependent differential regulation of mitochondrial bioenergetics in the heart and kidney cortex and outer medulla. (Tomar N, Zhang X, Kandel SM, Sadri S, Yang C, Liang M, Audi SH, Cowley AW Jr, Dash RK) Biochim Biophys Acta Bioenerg 2022 Feb 01;1863(2):148518 PMID: 34864090 PMCID: PMC8957717 SCOPUS ID: 2-s2.0-85120828118 12/06/2021 7 CitationsMechanistic computational modeling of the kinetics and regulation of NADPH oxidase 2 assembly and activation facilitating superoxide production. (Sadri S, Tomar N, Yang C, Audi SH, Cowley AW, Dash RK) Free Radic Res 2020 Oct;54(10):695-721 PMID: 33059489 PMCID: PMC8216485 SCOPUS ID: 2-s2.0-85095767680 10/17/2020 6 CitationsComputational/Experimental Interrogation of the Failing Heart-A Perspective on "Impaired Myocardial Energetics Causes Mechanical Dysfunction in Decompensated Failing Hearts". (Cowley AW Jr, Dash RK) Function (Oxf) 2020;1(2):zqaa022 PMID: 35330639 PMCID: PMC8788834 SCOPUS ID: 2-s2.0-85140267236 10/09/2020 Network mechanisms and dysfunction within an integrated computational model of progression through mitosis in the human cell cycle. (Terhune SS, Jung Y, Cataldo KM, Dash RK) PLoS Comput Biol 2020 Apr;16(4):e1007733 PMID: 32251461 PMCID: PMC7162553 SCOPUS ID: 2-s2.0-85083620688 04/07/2020 4 CitationsElucidating the roles of solubility and ventilation-perfusion mismatch in the second gas effect using a two-step model of gas exchange. (Korman B, Dash RK, Peyton PJ) J Appl Physiol (1985) 2020 Jun 01;128(6):1587-1593 PMID: 32191596 PMCID: PMC8424544 SCOPUS ID: 2-s2.0-85086285034 03/20/2020 1 CitationQuantification of mitochondrial membrane potential in the isolated rat lung using rhodamine 6G. (Audi SH, Cammarata A, Clough AV, Dash RK, Jacobs ER) J Appl Physiol (1985) 2020 Apr 01;128(4):892-906 PMID: 32134711 PMCID: PMC7191506 SCOPUS ID: 2-s2.0-85083624082 03/07/2020 12 CitationsA size-modified poisson-boltzmann ion channel model in a solvent of multiple ionic species: Application to voltage-dependent anion channel. (Xie D, Audi SH, Dash RK) J Comput Chem 2020 Jan 30;41(3):218-230 PMID: 31845398 PMCID: PMC8189662 SCOPUS ID: 2-s2.0-85075415763 12/18/2019 9 CitationsInfluence of a Hyperglycemic Microenvironment on a Diabetic Versus Healthy Rat Vascular Endothelium Reveals Distinguishable Mechanistic and Phenotypic Responses. (Haspula D, Vallejos AK, Moore TM, Tomar N, Dash RK, Hoffmann BR) Front Physiol 2019;10:558 PMID: 31133884 PMCID: PMC6524400 SCOPUS ID: 2-s2.0-85068264770 05/28/2019 18 CitationsIntegrated Computational Model of Lung Tissue Bioenergetics. (Zhang X, Dash RK, Clough AV, Xie D, Jacobs ER, Audi SH) Front Physiol 2019;10:191 PMID: 30906264 PMCID: PMC6418344 SCOPUS ID: 2-s2.0-85066496685 03/25/2019 3 CitationsSlow Ca2+ Efflux by Ca2+/H+ Exchange in Cardiac Mitochondria Is Modulated by Ca2+ Re-uptake via MCU, Extra-Mitochondrial pH, and H+ Pumping by FOF1-ATPase. (Haumann J, Camara AKS, Gadicherla AK, Navarro CD, Boelens AD, Blomeyer CA, Dash RK, Boswell MR, Kwok WM, Stowe DF) Front Physiol 2018;9:1914 PMID: 30804812 PMCID: PMC6378946 SCOPUS ID: 2-s2.0-85065923980 02/26/2019 10 CitationsA thermodynamically-constrained mathematical model for the kinetics and regulation of NADPH oxidase 2 complex-mediated electron transfer and superoxide production. (Tomar N, Sadri S, Cowley AW Jr, Yang C, Quryshi N, Pannala VR, Audi SH, Dash RK) Free Radic Biol Med 2019 Apr;134:581-597 PMID: 30769160 PMCID: PMC6588456 SCOPUS ID: 2-s2.0-85061529596 02/16/2019 12 CitationsmiR-21-5p regulates mitochondrial respiration and lipid content in H9C2 cells. (Nasci VL, Chuppa S, Griswold L, Goodreau KA, Dash RK, Kriegel AJ) Am J Physiol Heart Circ Physiol 2019 Mar 01;316(3):H710-H721 PMID: 30657727 PMCID: PMC6459316 SCOPUS ID: 2-s2.0-85062599405 01/19/2019 29 CitationsEffect of net gas volume changes on alveolar and arterial gas partial pressures in the presence of ventilation-perfusion mismatch. (Korman B, Dash RK, Peyton PJ) J Appl Physiol (1985) 2019 Mar 01;126(3):558-568 PMID: 30521424 PMCID: PMC6734074 SCOPUS ID: 2-s2.0-85062613697 12/07/2018 3 CitationsDetection of hydrogen peroxide production in the isolated rat lung using Amplex red. (Audi SH, Friedly N, Dash RK, Beyer AM, Clough AV, Jacobs ER) Free Radic Res 2018 Sep;52(9):1052-1062 PMID: 30175632 PMCID: PMC6298832 SCOPUS ID: 2-s2.0-85054191562 09/04/2018 10 CitationsIntegrated computational model of the bioenergetics of isolated lung mitochondria. (Zhang X, Dash RK, Jacobs ER, Camara AKS, Clough AV, Audi SH) PLoS One 2018;13(6):e0197921 PMID: 29889855 PMCID: PMC5995348 SCOPUS ID: 2-s2.0-85048330957 06/12/2018 10 CitationsCan Mathematical Modeling Explain the Measured Magnitude of the Second Gas Effect? (Korman B, Dash RK, Peyton PJ) Anesthesiology 2018 Jun;128(6):1075-1083 PMID: 29481374 PMCID: PMC5953815 SCOPUS ID: 2-s2.0-85053917318 02/27/2018 6 CitationsModeling the detailed kinetics of mitochondrial cytochrome c oxidase: Catalytic mechanism and nitric oxide inhibition. (Pannala VR, Camara AK, Dash RK) J Appl Physiol (1985) 2016 Nov 01;121(5):1196-1207 PMID: 27633738 PMCID: PMC5142251 SCOPUS ID: 2-s2.0-85021095865 09/17/2016 18 CitationsOptical Cryoimaging Reveals a Heterogeneous Distribution of Mitochondrial Redox State in ex vivo Guinea Pig Hearts and Its Alteration During Ischemia and Reperfusion. (Ranji M, Motlagh MM, Salehpour F, Sepehr R, Heisner JS, Dash RK, Camara AK) IEEE J Transl Eng Health Med 2016;4:1800210 PMID: 27574574 PMCID: PMC4993131 SCOPUS ID: 2-s2.0-84979987743 08/31/2016 10 CitationsMg(2+) differentially regulates two modes of mitochondrial Ca(2+) uptake in isolated cardiac mitochondria: implications for mitochondrial Ca(2+) sequestration. (Blomeyer CA, Bazil JN, Stowe DF, Dash RK, Camara AK) J Bioenerg Biomembr 2016 Jun;48(3):175-88 PMID: 26815005 PMCID: PMC5098337 SCOPUS ID: 2-s2.0-84955557614 01/28/2016 23 CitationsThe Pathway for Oxygen: Tutorial Modelling on Oxygen Transport from Air to Mitochondrion: The Pathway for Oxygen. (Bassingthwaighte JB, Raymond GM, Dash RK, Beard DA, Nolan M) Adv Exp Med Biol 2016;876:103-110 PMID: 26782201 PMCID: PMC4828238 SCOPUS ID: 2-s2.0-84958582096 01/20/2016 2 CitationsSimple accurate mathematical models of blood HbO2 and HbCO2 dissociation curves at varied physiological conditions: evaluation and comparison with other models. (Dash RK, Korman B, Bassingthwaighte JB) Eur J Appl Physiol 2016 Jan;116(1):97-113 PMID: 26298270 PMCID: PMC4699875 SCOPUS ID: 2-s2.0-84952975417 08/25/2015 31 CitationsLetter to the Editor: Mitochondrial cytochrome c oxidase: mechanism of action and role in regulating oxidative phosphorylation. (Pannala VR, Beard DA, Dash RK) J Appl Physiol (1985) 2015 Jul 15;119(2):157 PMID: 26177971 PMCID: PMC4504981 SCOPUS ID: 2-s2.0-84937872439 07/17/2015 7 CitationsEffects of p67phox on the mitochondrial oxidative state in the kidney of Dahl salt-sensitive rats: optical fluorescence 3-D cryoimaging. (Salehpour F, Ghanian Z, Yang C, Zheleznova NN, Kurth T, Dash RK, Cowley AW Jr, Ranji M) Am J Physiol Renal Physiol 2015 Aug 15;309(4):F377-82 PMID: 26062875 PMCID: PMC4596732 SCOPUS ID: 2-s2.0-84939495664 06/13/2015 15 CitationsMarkov chain Monte Carlo based analysis of post-translationally modified VDAC gating kinetics. (Tewari SG, Zhou Y, Otto BJ, Dash RK, Kwok WM, Beard DA) Front Physiol 2014;5:513 PMID: 25628567 PMCID: PMC4292549 SCOPUS ID: 2-s2.0-84925875428 01/30/2015 8 CitationsMechanistic characterization of the thioredoxin system in the removal of hydrogen peroxide. (Pannala VR, Dash RK) Free Radic Biol Med 2015 Jan;78:42-55 PMID: 25451645 PMCID: PMC4280359 SCOPUS ID: 2-s2.0-84913570411 12/03/2014 47 CitationsMitochondrial targets for volatile anesthetics against cardiac ischemia-reperfusion injury. (Agarwal B, Stowe DF, Dash RK, Bosnjak ZJ, Camara AK) Front Physiol 2014;5:341 PMID: 25278902 PMCID: PMC4165278 SCOPUS ID: 2-s2.0-84906518211 10/04/2014 32 CitationsDetermining the origins of superoxide and hydrogen peroxide in the mammalian NADH:ubiquinone oxidoreductase. (Bazil JN, Pannala VR, Dash RK, Beard DA) Free Radic Biol Med 2014 Dec;77:121-9 PMID: 25236739 PMCID: PMC4258523 SCOPUS ID: 2-s2.0-84908306065 09/23/2014 29 CitationsComputational analysis of Ca2+ dynamics in isolated cardiac mitochondria predicts two distinct modes of Ca2+ uptake. (Tewari SG, Camara AK, Stowe DF, Dash RK) J Physiol 2014 May 01;592(9):1917-30 PMID: 24591571 PMCID: PMC4230769 SCOPUS ID: 2-s2.0-84899905966 03/05/2014 19 CitationsA mechanistic mathematical model for the catalytic action of glutathione peroxidase. (Pannala VR, Bazil JN, Camara AK, Dash RK) Free Radic Res 2014 Apr;48(4):487-502 PMID: 24456207 PMCID: PMC4068149 SCOPUS ID: 2-s2.0-84895749936 01/25/2014 21 CitationsIsoflurane modulates cardiac mitochondrial bioenergetics by selectively attenuating respiratory complexes. (Agarwal B, Dash RK, Stowe DF, Bosnjak ZJ, Camara AK) Biochim Biophys Acta 2014 Mar;1837(3):354-65 PMID: 24355434 PMCID: PMC4084852 SCOPUS ID: 2-s2.0-84892375315 12/21/2013 32 CitationsEffect of P2X4 and P2X7 receptor antagonism on the pressure diuresis relationship in rats. (Menzies RI, Unwin RJ, Dash RK, Beard DA, Cowley AW Jr, Carlson BE, Mullins JJ, Bailey MA) Front Physiol 2013;4:305 PMID: 24187541 PMCID: PMC3807716 11/05/2013 A biophysically based mathematical model for the catalytic mechanism of glutathione reductase. (Pannala VR, Bazil JN, Camara AKS, Dash RK) Free Radic Biol Med 2013 Dec;65:1385-1397 PMID: 24120751 PMCID: PMC3870161 SCOPUS ID: 2-s2.0-84887108878 10/15/2013 28 CitationsCarrier-Mediated Transport through Biomembranes (Pradhan RK, Vinnakota KC, Beard DA, Dash RK) Transport in Biological Media (Edited by Kuznetsov AV and Becker SM) Chapter 5, 182-213, Elsevier (Academic Press), San Diego, 2013 10/01/2013 An online model composition tool for system biology models. (Coskun SA, Cicek AE, Lai N, Dash RK, Ozsoyoglu ZM, Ozsoyoglu G) BMC Syst Biol 2013 Sep 05;7:88 PMID: 24006914 PMCID: PMC3846440 SCOPUS ID: 2-s2.0-84883453083 09/07/2013 7 CitationsNumerical Methods and Simulations of Partial Differential Equations (Pradhan RK, Dash RK) Encyclopedia of Systems Biology (Edited by Dubitzky W, Wolkenhauer O, Cho KH, Yokota H) 1641-1645, Springer Verlag, New York, 2013 07/01/2013 Extra-matrix Mg2+ limits Ca2+ uptake and modulates Ca2+ uptake-independent respiration and redox state in cardiac isolated mitochondria. (Boelens AD, Pradhan RK, Blomeyer CA, Camara AK, Dash RK, Stowe DF) J Bioenerg Biomembr 2013 Jun;45(3):203-18 PMID: 23456198 PMCID: PMC3670670 SCOPUS ID: 2-s2.0-84878642065 03/05/2013 21 CitationsCarrier-Mediated Transport Through Biomembranes (Pradhan RK, Vinnakota KC, Beard DA, Dash RK) Transport in Biological Media May 2013:181-212 SCOPUS ID: 2-s2.0-84902069997 01/01/2013 3 CitationsDynamic buffering of mitochondrial Ca2+ during Ca2+ uptake and Na+-induced Ca2+ release. (Blomeyer CA, Bazil JN, Stowe DF, Pradhan RK, Dash RK, Camara AK) J Bioenerg Biomembr 2013 Jun;45(3):189-202 PMID: 23225099 PMCID: PMC4065551 SCOPUS ID: 2-s2.0-84878643622 12/12/2012 23 CitationsModeling the calcium sequestration system in isolated guinea pig cardiac mitochondria. (Bazil JN, Blomeyer CA, Pradhan RK, Camara AK, Dash RK) J Bioenerg Biomembr 2013 Jun;45(3):177-88 PMID: 23180139 PMCID: PMC3615037 SCOPUS ID: 2-s2.0-84878638876 11/28/2012 22 CitationsA biophysical model of the mitochondrial ATP-Mg/P(i) carrier. (Tewari SG, Dash RK, Beard DA, Bazil JN) Biophys J 2012 Oct 03;103(7):1616-25 PMID: 23062354 PMCID: PMC3471468 SCOPUS ID: 2-s2.0-84867025862 10/16/2012 8 CitationsMitochondrial handling of excess Ca2+ is substrate-dependent with implications for reactive oxygen species generation. (Aldakkak M, Stowe DF, Dash RK, Camara AK) Free Radic Biol Med 2013 Mar;56:193-203 PMID: 23010495 PMCID: PMC3542420 SCOPUS ID: 2-s2.0-84874117448 09/27/2012 26 CitationsModeling to link regional myocardial work, metabolism and blood flows. (Bassingthwaighte JB, Beard DA, Carlson BE, Dash RK, Vinnakota K) Ann Biomed Eng 2012 Nov;40(11):2379-98 PMID: 22915334 PMCID: PMC3471663 SCOPUS ID: 2-s2.0-84868354496 08/24/2012 11 CitationsPathCase-SB: integrating data sources and providing tools for systems biology research. (Coskun SA, Qi X, Cakmak A, Cheng E, Cicek AE, Yang L, Jadeja R, Dash RK, Lai N, Ozsoyoglu G, Ozsoyoglu ZM) BMC Syst Biol 2012 Jun 14;6(1):67 PMID: 22697505 PMCID: PMC3410775 SCOPUS ID: 2-s2.0-84862210684 06/16/2012 6 CitationsPathCase-SB: Database-enabled tools for regulatory metabolic networks (Qi X, Coskun SA, Cakmak A, Cheng E, Cicek EA, Yang L, Jadeja R, Syed S, Dash RK, Lai N, Ozsoyoglu G, Ozsoyoglu ZM) ACM SIGBioinformatics Record 2(3): 19-25, 2012 03/01/2012 Enhanced charge-independent mitochondrial free Ca(2+) and attenuated ADP-induced NADH oxidation by isoflurane: Implications for cardioprotection. (Agarwal B, Camara AK, Stowe DF, Bosnjak ZJ, Dash RK) Biochim Biophys Acta 2012 Mar;1817(3):453-65 PMID: 22155157 PMCID: PMC3269543 SCOPUS ID: 2-s2.0-84856457404 12/14/2011 18 CitationsCharacterization of Mg2+ inhibition of mitochondrial Ca2+ uptake by a mechanistic model of mitochondrial Ca2+ uniporter. (Pradhan RK, Qi F, Beard DA, Dash RK) Biophys J 2011 Nov 02;101(9):2071-81 PMID: 22067144 PMCID: PMC3207172 SCOPUS ID: 2-s2.0-80455137047 11/10/2011 27 CitationsDetailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. (Qi F, Pradhan RK, Dash RK, Beard DA) BMC Biochem 2011 Sep 26;12:53 PMID: 21943256 PMCID: PMC3195097 SCOPUS ID: 2-s2.0-80053379940 09/29/2011 32 CitationsStimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo. (Vinnakota KC, Dash RK, Beard DA) J Biol Chem 2011 Sep 02;286(35):30816-30822 PMID: 21757763 PMCID: PMC3162442 SCOPUS ID: 2-s2.0-80052210048 07/16/2011 20 CitationsA minimal model for the mitochondrial rapid mode of Ca²+ uptake mechanism. (Bazil JN, Dash RK) PLoS One 2011;6(6):e21324 PMID: 21731705 PMCID: PMC3121760 SCOPUS ID: 2-s2.0-79959573906 07/07/2011 16 CitationsErratum: Mitochondrial free [Ca2+ ] increases during ATP/ADP antiport and ADP phosphorylation: Exploration of mechanisms (Biophysical Journal (2010) 99 (997-1006)) (Haumann J, Dash RK, Stowe DF, Boelens AD, Beard DA, Camara AKS) Biophysical Journal 15 December 2010;99(12):4078 SCOPUS ID: 2-s2.0-78650163059 12/15/2010 Characterization of membrane potential dependency of mitochondrial Ca2+ uptake by an improved biophysical model of mitochondrial Ca2+ uniporter. (Pradhan RK, Qi F, Beard DA, Dash RK) PLoS One 2010 Oct 08;5(10):e13278 PMID: 20949039 PMCID: PMC2951907 SCOPUS ID: 2-s2.0-78149450143 10/16/2010 20 CitationsKinetics and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I). (Chen X, Qi F, Dash RK, Beard DA) Biophys J 2010 Sep 08;99(5):1426-36 PMID: 20816054 PMCID: PMC2931722 SCOPUS ID: 2-s2.0-77956604712 09/08/2010 14 CitationsMitochondrial free [Ca2+] increases during ATP/ADP antiport and ADP phosphorylation: exploration of mechanisms. (Haumann J, Dash RK, Stowe DF, Boelens AD, Beard DA, Camara AK) Biophys J 2010 Aug 09;99(4):997-1006 PMID: 20712982 PMCID: PMC2920628 SCOPUS ID: 2-s2.0-77958171178 08/18/2010 27 CitationsA database of thermodynamic quantities for the reactions of glycolysis and the tricarboxylic acid cycle. (Li X, Dash RK, Pradhan RK, Qi F, Thompson M, Vinnakota KC, Wu F, Yang F, Beard DA) J Phys Chem B 2010 Dec 16;114(49):16068-82 PMID: 20446702 PMCID: PMC3299200 SCOPUS ID: 2-s2.0-77956568325 05/08/2010 24 CitationsA biophysically based mathematical model for the kinetics of mitochondrial Na+-Ca2+ antiporter. (Pradhan RK, Beard DA, Dash RK) Biophys J 2010 Jan 20;98(2):218-30 PMID: 20338843 PMCID: PMC2808480 SCOPUS ID: 2-s2.0-77049095167 03/27/2010 22 CitationsAn Improved Algorithm and Its Parallel Implementation for Solving a General Blood-Tissue Transport and Metabolism Model. (Xie D, Dash RK, Beard DA) J Comput Phys 2009 Nov 01;228(20):7850-7861 PMID: 20161089 PMCID: PMC2744406 SCOPUS ID: 2-s2.0-69049099830 02/18/2010 2 CitationsErratum to: Blood HbO2 and HbCO2 dissociation curves at varied O2, CO2, pH, 2,3-DPG and temperature levels. (Dash RK, Bassingthwaighte JB) Ann Biomed Eng 2010 Apr;38(4):1683-701 PMID: 20162361 PMCID: PMC2862600 SCOPUS ID: 2-s2.0-77952009688 02/18/2010 51 CitationsDesign of experiments for identification of complex biochemical systems with applications to mitochondrial bioenergetics. (Vinnakota KC, Beard DA, Dash RK) Annu Int Conf IEEE Eng Med Biol Soc 2009;2009:4171-4 PMID: 19964622 PMCID: PMC2810972 SCOPUS ID: 2-s2.0-77951007535 12/08/2009 1 CitationGenerating rate equations for complex enzyme systems by a computer-assisted systematic method. (Qi F, Dash RK, Han Y, Beard DA) BMC Bioinformatics 2009 Aug 04;10:238 PMID: 19653903 PMCID: PMC2729780 SCOPUS ID: 2-s2.0-69049085645 08/06/2009 32 CitationsBISEN: Biochemical Simulation Environment. (Vanlier J, Wu F, Qi F, Vinnakota KC, Han Y, Dash RK, Yang F, Beard DA) Bioinformatics 2009 Mar 15;25(6):836-7 PMID: 19244386 PMCID: PMC2732302 SCOPUS ID: 2-s2.0-62549165395 02/27/2009 12 CitationsA biophysically based mathematical model for the kinetics of mitochondrial calcium uniporter. (Dash RK, Qi F, Beard DA) Biophys J 2009 Feb 18;96(4):1318-32 PMID: 19217850 PMCID: PMC2717240 SCOPUS ID: 2-s2.0-62649106276 02/17/2009 38 CitationsErratum: Modelling of Cellular Metabolism and Microcirculatory Transport (Microcirculation 10.1080/10739680802019709) (Beard DA, Wu F, Cabrera ME, Dash RK) Microcirculation 2008;15(8):841 SCOPUS ID: 2-s2.0-57149118020 12/09/2008 Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies. (Li Y, Dash RK, Kim J, Saidel GM, Cabrera ME) Am J Physiol Cell Physiol 2009 Jan;296(1):C25-46 PMID: 18829894 PMCID: PMC2636997 SCOPUS ID: 2-s2.0-58349093912 10/03/2008 32 CitationsMetabolic dynamics in skeletal muscle during acute reduction in blood flow and oxygen supply to mitochondria: in-silico studies using a multi-scale, top-down integrated model. (Dash RK, Li Y, Kim J, Beard DA, Saidel GM, Cabrera ME) PLoS One 2008 Sep 09;3(9):e3168 PMID: 18779864 PMCID: PMC2526172 SCOPUS ID: 2-s2.0-52649100046 09/10/2008 24 CitationsModeling of cellular metabolism and microcirculatory transport. (Beard DA, Wu F, Cabrera ME, Dash RK) Microcirculation 2008 Nov;15(8):777-93 PMID: 18608987 SCOPUS ID: 2-s2.0-52649174908 07/09/2008 15 CitationsAnalysis of cardiac mitochondrial Na+-Ca2+ exchanger kinetics with a biophysical model of mitochondrial Ca2+ handling suggests a 3:1 stoichiometry. (Dash RK, Beard DA) J Physiol 2008 Jul 01;586(13):3267-85 PMID: 18467367 PMCID: PMC2538784 SCOPUS ID: 2-s2.0-47249162028 05/10/2008 78 CitationsModeling cellular metabolism and energetics in skeletal muscle: large-scale parameter estimation and sensitivity analysis. (Dash RK, Li Y, Kim J, Saidel GM, Cabrera ME) IEEE Trans Biomed Eng 2008 Apr;55(4):1298-318 PMID: 18390321 SCOPUS ID: 2-s2.0-41149083382 04/09/2008 29 CitationsModeling oxygen and carbon dioxide transport and exchange using a closed loop circulatory system. (Carlson BE, Anderson JC, Raymond GM, Dash RK, Bassingthwaighte JB) Adv Exp Med Biol 2008;614:353-60 PMID: 18290346 PMCID: PMC3377501 SCOPUS ID: 2-s2.0-84934440804 02/23/2008 7 CitationsA computational model of skeletal muscle metabolism linking cellular adaptations induced by altered loading states to metabolic responses during exercise. (Dash RK, Dibella JA 2nd, Cabrera ME) Biomed Eng Online 2007 Apr 20;6:14 PMID: 17448235 PMCID: PMC1868741 SCOPUS ID: 2-s2.0-34249062728 04/24/2007 27 CitationsLinking pulmonary oxygen uptake, muscle oxygen utilization and cellular metabolism during exercise. (Lai N, Camesasca M, Saidel GM, Dash RK, Cabrera ME) Ann Biomed Eng 2007 Jun;35(6):956-69 PMID: 17380394 PMCID: PMC4124918 SCOPUS ID: 2-s2.0-34249685448 03/24/2007 21 CitationsAn efficient deconvolution algorithm for estimating oxygen consumption during muscle activities. (Dash RK, Somersalo E, Cabrera ME, Calvetti D) Comput Methods Programs Biomed 2007 Mar;85(3):247-56 PMID: 17275136 PMCID: PMC1994789 SCOPUS ID: 2-s2.0-33846894465 02/06/2007 3 CitationsLocal regularization method applied to estimating oxygen consumption during muscle activities (Calvetti D, Dash RK, Somersalo E, Cabrera ME) Inverse Problems 22: 229-243, 2006 10/01/2006 Simultaneous blood-tissue exchange of oxygen, carbon dioxide, bicarbonate, and hydrogen ion. (Dash RK, Bassingthwaighte JB) Ann Biomed Eng 2006 Jul;34(7):1129-48 PMID: 16775761 PMCID: PMC4232240 SCOPUS ID: 2-s2.0-33745461259 06/16/2006 63 CitationsRelating pulmonary oxygen uptake to muscle oxygen consumption at exercise onset: in vivo and in silico studies. (Lai N, Dash RK, Nasca MM, Saidel GM, Cabrera ME) Eur J Appl Physiol 2006 Jul;97(4):380-94 PMID: 16636861 PMCID: PMC4124916 SCOPUS ID: 2-s2.0-33745459956 04/26/2006 25 CitationsLocal regularization method applied to estimating oxygen consumption during muscle activities (Calvetti D, Dash RK, Somersalo E, Cabrera ME) Inverse Problems 1 February 2006;22(1):229-243 SCOPUS ID: 2-s2.0-31844431886 02/01/2006 6 CitationsEstimating in vitro mitochondrial oxygen consumption during muscle contraction and recovery: a novel approach that accounts for diffusion. (Dash RK, Bell BM, Kushmerick MJ, Vicini P) Ann Biomed Eng 2005 Mar;33(3):343-55 PMID: 15868725 SCOPUS ID: 2-s2.0-17444368348 05/05/2005 5 CitationsBlood HbO2 and HbCO2 dissociation curves at varied O2, CO2, pH, 2,3-DPG and temperature levels. (Dash RK, Bassingthwaighte JB) Ann Biomed Eng 2004 Dec;32(12):1676-93 PMID: 15682524 SCOPUS ID: 2-s2.0-12344261687 02/03/2005 54 CitationsOn a class of Boussinesq equations for shallow water waves (Daripa P, Dash RK) Lect Notes Comp Sci 2668: 764-773, 2003 07/01/2003 A class of model equations for bi-directional propagation of capillary-gravity waves (Daripa P, Dash RK) Int J Eng Sci 41(2): 201-218, 2003 02/01/2003 On a class of Boussinesq equations for shallow water waves (Daripa P, Dash RK) Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2003;2668:764-773 SCOPUS ID: 2-s2.0-35248888554 01/01/2003 A class of model equations for bi-directional propagation of capillary-gravity waves (Daripa P, Dash RK) International Journal of Engineering Science January 2003;41(2):201-218 SCOPUS ID: 2-s2.0-0037211825 01/01/2003 27 CitationsA numerical study of pulsatile blood flow in an eccentric catheterized artery using a fast algorithm (Daripa P, Dash RK) J Eng Math 42(1): 1-22, 2002 04/01/2002 Analytical and numerical studies of a singularly perturbed Boussinesq equation (Dash RK, Daripa P) Applied Mathematics and Computation 15 February 2002;126(1):1-30 SCOPUS ID: 2-s2.0-0037082773 02/15/2002 20 CitationsAnalytical and numerical studies of a singularly perturbed Boussinesq equation (Dash RK, Daripa P) Appl Math Comput 126(1): 1-30, 2002 01/01/2002 A numerical study of pulsatile blood flow in an eccentric catheterized artery using a fast algorithm (Daripa P, Dash RK) Journal of Engineering Mathematics January 2002;42(1):1-22 SCOPUS ID: 2-s2.0-0036205944 01/01/2002 27 CitationsWeakly non-local solitary wave solutions of a singularly perturbed Boussinesq equation (Daripa P, Dash RK) Mathematics and Computers in Simulation 2001;55(4-6):393-405 SCOPUS ID: 2-s2.0-0034926297 08/01/2001 12 CitationsNumerical study of flow in a constricted curved annulus: an application to flow in a catheterized artery (Jayaraman G, Dash RK) J Eng Math 40(4): 355-376, 2001 04/01/2001 Weakly non-local solitary wave solutions of a singularly perturbed Boussinesq equation (Daripa P, Dash RK) Math Comp Simul 55: 393-405, 2001 04/01/2001 Numerical study of flow in constricted curved annulus: An application to flow in catheterised artery (Jayaraman G, Dash RK) Journal of Engineering Mathematics August 2001;40(4):355-375 SCOPUS ID: 2-s2.0-0035418239 01/01/2001 22 CitationsShear augmented dispersion of a solute in a casson fluid flowing in a conduit. (Dash RK, Jayaraman G, Mehta KN) Ann Biomed Eng 2000 Apr;28(4):373-85 PMID: 10870894 SCOPUS ID: 2-s2.0-0033623701 06/28/2000 61 CitationsFlow in a catheterized curved artery with stenosis. (Dash RK, Jayaraman G, Mehta KN) J Biomech 1999 Jan;32(1):49-61 PMID: 10050951 SCOPUS ID: 2-s2.0-0032950593 03/02/1999 87 CitationsEffect of yield stress on the flow of a Casson fluid in a homogeneous porous medium bounded by a circular tube (Dash RK, Mehta KN, Jayaraman G) Appl Sci Res 57(1): 133-149, 1997 01/01/1997 Casson fluid flow in a pipe filled with a homogeneous porous medium (Dash RK, Mehta KN, Jayaraman G) Int J Eng Sci 34(10): 1145-1156, 1996 10/01/1996 Estimation of increased flow resistance in a narrow catheterized artery--a theoretical model. (Dash RK, Jayaraman G, Mehta KN) J Biomech 1996 Jul;29(7):917-30 PMID: 8809622 SCOPUS ID: 2-s2.0-0030199797 07/01/1996 81 CitationsEffect of yield stress on the flow of a casson fluid in a homogeneous porous medium bounded by a circular tube (Dash RK, Mehta KN, Jayaraman G) Applied Scientific Research (The Hague) June 1996;57(2):133-149 SCOPUS ID: 2-s2.0-0030313318 06/01/1996 22 CitationsCasson fluid flow in a pipe filled with a homogeneous porous medium (Dash RK, Mehta KN, Jayaraman G) International Journal of Engineering Science August 1996;34(10):1145-1156 SCOPUS ID: 2-s2.0-0001195756 01/01/1996 273 Citations Last update: 11/10/2023