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Andreas M. Beyer PhD

Andreas M. Beyer PhD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Cardiology
Program: Research

Member of the Cancer Center
Member of the Cardiovascular Center

I am willing to mentor a junior faculty member.

Research Experience

  • Cardiovascular Abnormalities
  • Cardiovascular Diseases
  • Coronary Artery Disease
  • Coronary Circulation
  • DNA, Mitochondrial
  • Endothelial Cells
  • Free Radical Scavengers
  • Free Radicals
  • Heart Diseases
  • Hypertension
  • Mitochondria
  • Mitochondria, Heart
  • Mitochondrial Diseases
  • Oxidative Stress
  • Pharmacology
  • Physiology
  • Reperfusion Injury
  • Telomerase
  • Vascular Diseases
  • cardio oncology
  • MCW Program / Core Facilities

  • Cardiovascular Center
  • cancer center
  • Publications (49)

  • Hypertension preserves the magnitude of microvascular flow-mediated dilation following transient elevation in intraluminal pressure. (Hughes WE, Zinkevich N, Gutterman DD, Beyer AM) Physiol Rep 2021 Feb;9(3):e14507 PMID: 33587335 PMCID: PMC7883808 SCOPUS ID: 2-s2.0-85100849665 02/16/2021    
  • Critical Interaction Between Telomerase and Autophagy in Mediating Flow-Induced Human Arteriolar Vasodilation. (Hughes WE, Chabowski DS, Ait-Aissa K, Fetterman JL, Hockenberry J, Beyer AM, Gutterman DD) Arterioscler Thromb Vasc Biol 2021 01;41(1):446-457 PMID: 33232201 PMCID: PMC7770118 SCOPUS ID: 2-s2.0-85098224505 11/25/2020    
  • Sweat the small stuff: The human microvasculature and heart disease. (Katunaric B, Cohen KE, Beyer AM, Gutterman DD, Freed JK) Microcirculation 2020 Sep 16:e12658 PMID: 32939881 PMCID: PMC7960576 SCOPUS ID: 2-s2.0-85091684344 09/18/2020    
  • Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy. (Viereck J, Bührke A, Foinquinos A, Chatterjee S, Kleeberger JA, Xiao K, Janssen-Peters H, Batkai S, Ramanujam D, Kraft T, Cebotari S, Gueler F, Beyer AM, Schmitz J, Bräsen JH, Schmitto JD, Gyöngyösi M, Löser A, Hirt MN, Eschenhagen T, Engelhardt S, Bär C, Thum T) Eur Heart J 2020 09 21;41(36):3462-3474 PMID: 32657324 SCOPUS ID: 2-s2.0-85089665699 07/14/2020       8 Citations
  • Vascular autophagy in health and disease (Hughes WE, Beyer AM, Gutterman DD) Basic Research in Cardiology 1 July 2020;115(4) SCOPUS ID: 2-s2.0-85086002230 07/01/2020    
  • Vascular autophagy in health and disease. (Hughes WE, Beyer AM, Gutterman DD) Basic Res Cardiol 2020 06 06;115(4):41 PMID: 32506214 SCOPUS ID: 2-s2.0-85086002230 06/09/2020       9 Citations
  • BCR-ABL tyrosine kinase inhibitors promote pathological changes in dilator phenotype in the human microvasculature. (Durand MJ, Hader SN, Derayunan A, Zinkevich N, McIntosh JJ, Beyer AM) Microcirculation 2020 10;27(7):e12625 PMID: 32395853 PMCID: PMC7606774 SCOPUS ID: 2-s2.0-85090145617 05/13/2020    
  • Detrimental effects of chemotherapy on human coronary microvascular function. (Hader SN, Zinkevich N, Norwood Toro LE, Kriegel AJ, Kong A, Freed JK, Gutterman DD, Beyer AM) Am J Physiol Heart Circ Physiol 2019 10 01;317(4):H705-H710 PMID: 31397169 PMCID: PMC6843017 SCOPUS ID: 2-s2.0-85072508643 08/10/2019       2 Citations
  • Cancer therapy-induced cardiovascular toxicity: old/new problems and old drugs. (Beyer AM, Bonini MG, Moslehi J) Am J Physiol Heart Circ Physiol 2019 07 01;317(1):H164-H167 PMID: 31172808 PMCID: PMC6692734 SCOPUS ID: 2-s2.0-85069238135 06/08/2019       3 Citations
  • Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease. (Ait-Aissa K, Blaszak SC, Beutner G, Tsaih SW, Morgan G, Santos JH, Flister MJ, Joyce DL, Camara AKS, Gutterman DD, Donato AJ, Porter GA Jr, Beyer AM) Sci Rep 2019 05 20;9(1):7623 PMID: 31110224 PMCID: PMC6527853 SCOPUS ID: 2-s2.0-85066048228 05/22/2019       12 Citations
  • Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury. (Ait-Aissa K, Heisner JS, Norwood Toro LE, Bruemmer D, Doyon G, Harmann L, Geurts A, Camara AKS, Beyer AM) Front Cardiovasc Med 2019;6:31 PMID: 31001540 PMCID: PMC6454001 04/20/2019    
  • Visualization and quantification of mitochondrial structure in the endothelium of intact arteries. (Durand MJ, Ait-Aissa K, Levchenko V, Staruschenko A, Gutterman DD, Beyer AM) Cardiovasc Res 2019 08 01;115(10):1546-1556 PMID: 30476208 PMCID: PMC6648341 SCOPUS ID: 2-s2.0-85072658081 11/27/2018       4 Citations
  • Vascular autophagy in physiology and pathology. (Hughes WE, Beyer AM) Am J Physiol Heart Circ Physiol 2019 01 01;316(1):H183-H185 PMID: 30412440 PMCID: PMC6383357 SCOPUS ID: 2-s2.0-85059796597 11/10/2018    
  • Detection of hydrogen peroxide production in the isolated rat lung using Amplex red. (Audi SH, Friedly N, Dash RK, Beyer AM, Clough AV, Jacobs ER) Free Radic Res 2018 Sep;52(9):1052-1062 PMID: 30175632 PMCID: PMC6298832 SCOPUS ID: 2-s2.0-85054191562 09/04/2018       4 Citations
  • Lysophosphatidic acid acts on LPA1 receptor to increase H2 O2 during flow-induced dilation in human adipose arterioles. (Chabowski DS, Kadlec AO, Ait-Aissa K, Hockenberry JC, Pearson PJ, Beyer AM, Gutterman DD) Br J Pharmacol 2018 11;175(22):4266-4280 PMID: 30153326 PMCID: PMC6193883 SCOPUS ID: 2-s2.0-85054757437 08/29/2018       5 Citations
  • Telomerase: Location, Location, Location? (Beyer AM, Norwood Toro LE) Arterioscler Thromb Vasc Biol 2018 06;38(6):1247-1249 PMID: 29793988 PMCID: PMC6028234 SCOPUS ID: 2-s2.0-85051742596 05/26/2018       2 Citations
  • Chemotherapeutic-Induced Cardiovascular Dysfunction: Physiological Effects, Early Detection-The Role of Telomerase to Counteract Mitochondrial Defects and Oxidative Stress. (Quryshi N, Norwood Toro LE, Ait-Aissa K, Kong A, Beyer AM) Int J Mol Sci 2018 Mar 10;19(3) PMID: 29534446 PMCID: PMC5877658 SCOPUS ID: 2-s2.0-85044136313 03/15/2018       5 Citations
  • Hyperoxia Causes Mitochondrial Fragmentation in Pulmonary Endothelial Cells by Increasing Expression of Pro-Fission Proteins. (Ma C, Beyer AM, Durand M, Clough AV, Zhu D, Norwood Toro L, Terashvili M, Ebben JD, Hill RB, Audi SH, Medhora M, Jacobs ER) Arterioscler Thromb Vasc Biol 2018 03;38(3):622-635 PMID: 29419407 PMCID: PMC5823793 SCOPUS ID: 2-s2.0-85047900228 02/09/2018       10 Citations
  • Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction. (Ait-Aissa K, Kadlec AO, Hockenberry J, Gutterman DD, Beyer AM) Am J Physiol Heart Circ Physiol 2018 05 01;314(5):H1053-H1060 PMID: 29351466 PMCID: PMC6008150 SCOPUS ID: 2-s2.0-85046904084 01/20/2018       15 Citations
  • PGC-1α (Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α) Overexpression in Coronary Artery Disease Recruits NO and Hydrogen Peroxide During Flow-Mediated Dilation and Protects Against Increased Intraluminal Pressure. (Kadlec AO, Chabowski DS, Ait-Aissa K, Hockenberry JC, Otterson MF, Durand MJ, Freed JK, Beyer AM, Gutterman DD) Hypertension 2017 07;70(1):166-173 PMID: 28533333 PMCID: PMC5485836 SCOPUS ID: 2-s2.0-85019610110 05/24/2017       24 Citations
  • 5,6-δ-DHTL, a stable metabolite of arachidonic acid, is a potential EDHF that mediates microvascular dilation. (Levi-Rosenzvig R, Beyer AM, Hockenberry J, Ben-Shushan RS, Chuyun D, Atiya S, Tamir S, Gutterman DD, Szuchman-Sapir A) Free Radic Biol Med 2017 02;103:87-94 PMID: 28007573 SCOPUS ID: 2-s2.0-85006860846 12/23/2016       2 Citations
  • Transition in the mechanism of flow-mediated dilation with aging and development of coronary artery disease. (Beyer AM, Zinkevich N, Miller B, Liu Y, Wittenburg AL, Mitchell M, Galdieri R, Sorokin A, Gutterman DD) Basic Res Cardiol 2017 01;112(1):5 PMID: 27995364 PMCID: PMC6758541 SCOPUS ID: 2-s2.0-85006456806 12/21/2016       26 Citations
  • Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease. (Ait-Aissa K, Ebben JD, Kadlec AO, Beyer AM) Pharmacol Res 2016 09;111:422-433 PMID: 27394166 PMCID: PMC5026584 SCOPUS ID: 2-s2.0-84978880166 07/11/2016       21 Citations
  • Vascular Actions of Angiotensin 1-7 in the Human Microcirculation: Novel Role for Telomerase. (Durand MJ, Zinkevich NS, Riedel M, Gutterman DD, Nasci VL, Salato VK, Hijjawi JB, Reuben CF, North PE, Beyer AM) Arterioscler Thromb Vasc Biol 2016 06;36(6):1254-62 PMID: 27079876 PMCID: PMC4882242 SCOPUS ID: 2-s2.0-84963556451 04/16/2016       27 Citations
  • Mitochondrial signaling in the vascular endothelium: beyond reactive oxygen species. (Kadlec AO, Beyer AM, Ait-Aissa K, Gutterman DD) Basic Res Cardiol 2016 May;111(3):26 PMID: 26992928 PMCID: PMC6749826 SCOPUS ID: 2-s2.0-84961777268 03/20/2016       24 Citations
  • The Human Microcirculation: Regulation of Flow and Beyond. (Gutterman DD, Chabowski DS, Kadlec AO, Durand MJ, Freed JK, Ait-Aissa K, Beyer AM) Circ Res 2016 Jan 08;118(1):157-72 PMID: 26837746 PMCID: PMC4742348 SCOPUS ID: 2-s2.0-84954534623 02/04/2016       118 Citations
  • Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation. (Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD) Circ Res 2016 Mar 04;118(5):856-66 PMID: 26699654 PMCID: PMC4772813 SCOPUS ID: 2-s2.0-84952008563 12/25/2015       52 Citations
  • Peptide inhibitors of Telomerase nuclear translocation and therapeutic uses thereof (Johnathan D. Ebben, Andreas M. Beyer) US Provisional Patent App- 62/211,524 08/25/2015    
  • Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins. (Starks RD, Beyer AM, Guo DF, Boland L, Zhang Q, Sheffield VC, Rahmouni K) PLoS Genet 2015 Jun;11(6):e1005311 PMID: 26103456 PMCID: PMC4478011 SCOPUS ID: 2-s2.0-84937800930 06/24/2015       27 Citations
  • H2S in the Vasculature: Controversy of Mechanisms in Physiology, Pathology and Beyond (Nishijima, Y Beyer, AM) Cardiol Pharmacol Nishijima, Y., and A. M. Beyer. "H2S in the Vasculature: Controversy of Mechanisms in Physiology, Pathology and Beyond." Cardiol Pharmacol 4.135 (2015): 24-26. 05/01/2015    
  • An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles. (Beyer AM, Durand MJ, Hockenberry J, Gamblin TC, Phillips SA, Gutterman DD) Am J Physiol Heart Circ Physiol 2014 Dec 01;307(11):H1587-93 PMID: 25260615 PMCID: PMC4255007 SCOPUS ID: 2-s2.0-84913573408 09/28/2014       46 Citations
  • Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation. (Freed JK, Beyer AM, LoGiudice JA, Hockenberry JC, Gutterman DD) Circ Res 2014 Aug 15;115(5):525-32 PMID: 24920698 PMCID: PMC4640193 SCOPUS ID: 2-s2.0-84906100241 06/13/2014       58 Citations
  • Response to "Does angiotensin-dependent superoxide production help to prevent salt-induced endothelial dysfunction in 2 kidney-1 clip hypertensive rats?". (Beyer AM, Fredrich K, Lombard JH) Am J Hypertens 2014 Apr;27(4):640 PMID: 24614863 PMCID: PMC4542814 SCOPUS ID: 2-s2.0-84897882088 03/13/2014    
  • Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. (Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH) Am J Physiol Heart Circ Physiol 2014 Feb;306(3):H339-47 PMID: 24322611 PMCID: PMC3920146 SCOPUS ID: 2-s2.0-84893409421 12/11/2013       8 Citations
  • AT1 receptors prevent salt-induced vascular dysfunction in isolated middle cerebral arteries of 2 kidney-1 clip hypertensive rats. (Beyer AM, Fredrich K, Lombard JH) Am J Hypertens 2013 Dec;26(12):1398-404 PMID: 23934707 PMCID: PMC3816625 SCOPUS ID: 2-s2.0-84890515006 08/13/2013       6 Citations
  • In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry. (Peng Y, Yu D, Gregorich Z, Chen X, Beyer AM, Gutterman DD, Ge Y) J Muscle Res Cell Motil 2013 Aug;34(3-4):199-210 PMID: 23881156 PMCID: PMC3849107 SCOPUS ID: 2-s2.0-84890043290 07/25/2013       29 Citations
  • Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity. (Beyer AM, Guo DF, Rahmouni K) J Hypertens 2013 Apr;31(4):730-8 PMID: 23425706 PMCID: PMC5684878 SCOPUS ID: 2-s2.0-84875214685 02/22/2013       27 Citations
  • Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. (Beyer AM, Raffai G, Weinberg B, Fredrich K, Lombard JH) Hypertension 2012 Aug;60(2):404-10 PMID: 22710645 PMCID: PMC3444144 SCOPUS ID: 2-s2.0-84864282707 06/20/2012       17 Citations
  • Hexosamine pathway activation and O-linked-N-acetylglucosamine: novel mediators of endothelial dysfunction in hyperglycemia and diabetes. (Beyer AM, Weihrauch D) Vascul Pharmacol 2012 Mar-Apr;56(3-4):113-4 PMID: 22289438 SCOPUS ID: 2-s2.0-84858150148 02/01/2012       3 Citations
  • Regulation of the human coronary microcirculation. (Beyer AM, Gutterman DD) J Mol Cell Cardiol 2012 Apr;52(4):814-21 PMID: 22033434 PMCID: PMC3306504 SCOPUS ID: 2-s2.0-84858297384 10/29/2011       36 Citations
  • Inactivation of Bardet-Biedl syndrome genes causes kidney defects. (Guo DF, Beyer AM, Yang B, Nishimura DY, Sheffield VC, Rahmouni K) Am J Physiol Renal Physiol 2011 Feb;300(2):F574-80 PMID: 21106857 PMCID: PMC3043995 SCOPUS ID: 2-s2.0-79551557954 11/26/2010       17 Citations
  • Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes. (Beyer AM, Guo DF, Sheffield VC, Rahmouni K) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1902-7 PMID: 20852044 PMCID: PMC3006278 SCOPUS ID: 2-s2.0-78649739388 09/21/2010       10 Citations
  • Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta. (Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD) Arterioscler Thromb Vasc Biol 2010 Mar;30(3):518-25 PMID: 20018933 PMCID: PMC2850258 SCOPUS ID: 2-s2.0-77649134985 12/19/2009       20 Citations
  • Endothelium-specific interference with peroxisome proliferator activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet. (Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD) Circ Res 2008 Sep 12;103(6):654-61 PMID: 18676352 PMCID: PMC2583077 SCOPUS ID: 2-s2.0-53249111805 08/05/2008       74 Citations
  • Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles. (de Lange WJ, Halabi CM, Beyer AM, Sigmund CD) Physiol Genomics 2008 Sep 17;35(1):1-4 PMID: 18612081 PMCID: PMC2574738 SCOPUS ID: 2-s2.0-56149117324 07/10/2008       48 Citations
  • Interference with PPARγ signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling (Hypertension (2008) 51, (867-871)) (Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, De Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM) Hypertension April 2008;51(4) SCOPUS ID: 2-s2.0-43249123388 04/01/2008    
  • Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. (Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD) Cell Metab 2008 Mar;7(3):215-26 PMID: 18316027 PMCID: PMC2275166 SCOPUS ID: 2-s2.0-39649100393 03/05/2008       123 Citations
  • Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. (Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM) Hypertension 2008 Apr;51(4):867-71 PMID: 18285614 PMCID: PMC2408877 SCOPUS ID: 2-s2.0-42049101837 02/21/2008       96 Citations
  • Gene expression profiling of potential PPARgamma target genes in mouse aorta. (Keen HL, Ryan MJ, Beyer A, Mathur S, Scheetz TE, Gackle BD, Faraci FM, Casavant TL, Sigmund CD) Physiol Genomics 2004 Jun 17;18(1):33-42 PMID: 15054141 SCOPUS ID: 2-s2.0-4243120941 04/01/2004       43 Citations
  • Last update: 03/15/2021