Medical College of Wisconsin
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Nancy M. Dahms PhD

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Professor

Institution: Medical College of Wisconsin
Department: Biochemistry

Member of the Cancer Center

View Curriculum Vitae

Research Experience

  • Fabry Disease
  • Glycoconjugates
  • Lectins
  • Lysosomal Storage Diseases
  • Lysosomes
  • Membrane Glycoproteins
  • Membrane Proteins
  • Organelles
  • Receptor, IGF Type 2
  • Recombinant protein expression systems (Pichia pastoris yeast, Baculovirus insect cells, E. coli, mammalian)
  • Quality control mechanisms in the secretory pathway
  • Receptor, Mannose 6-phosphate
  • Rat model of Fabry Disease

    • Leadership Positions

  • President, Society for Glycobiology 2021
  • President Elect, Society for Glycobiology 2020
  • Chair, Radiation Safety Committee 2000-2006
  • Interim Chair, Department of Biochemistry 2009
  • Vice President Faculty Council 2004-2005
  • President Faculty Council 2006-2007
  • Sr Vice President Faculty Council 2005-2006
  • Vice-Chairman, Curriculum and Evaluation Committee 2001-2002

    • Publications (87)

  • Schwann cell release of p11 induces sensory neuron hyperactivity in Fabry disease. (Waltz TB, Chao D, Prodoehl EK, Ehlers VL, Dharanikota BS, Dahms NM, Isaeva E, Hogan QH, Pan B, Stucky CL) bioRxiv 2023 May 28 PMID: 37292928 PMCID: PMC10245981 06/09/2023    
  • Multiple Domains of Staphylococcal Superantigen-like Protein 11 (SSL11) Contribute to Neutrophil Inhibition. (Yang C, Barbieri JT, Dahms NM, Chen C) Biochemistry 2022 Apr 05;61(7):616-624 PMID: 35285627 PMCID: PMC9817067 SCOPUS ID: 2-s2.0-85127145605 03/15/2022       4 Citations
  • Platelet and myeloid cell phenotypes in a rat model of Fabry disease. (Kanack AJ, Aoki K, Tiemeyer M, Dahms NM) FASEB J 2021 Aug;35(8):e21818 PMID: 34320241 PMCID: PMC8341388 SCOPUS ID: 2-s2.0-85111530832 07/29/2021    
  • Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate. (Miller JJ, Bohnsack RN, Olson LJ, Ishihara M, Aoki K, Tiemeyer M, Dahms NM) Sci Rep 2021 Apr 15;11(1):8213 PMID: 33859256 PMCID: PMC8050316 SCOPUS ID: 2-s2.0-85104287178 04/17/2021       2 Citations
  • Auditory brainstem responses in aging dark agouti rats. (Beltrame AK, Dahms NM, Runge CL) Biosci Rep 2021 Feb 26;41(2) PMID: 33506259 PMCID: PMC7897922 SCOPUS ID: 2-s2.0-85102217469 01/29/2021       3 Citations
  • Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor. (Olson LJ, Misra SK, Ishihara M, Battaile KP, Grant OC, Sood A, Woods RJ, Kim JP, Tiemeyer M, Ren G, Sharp JS, Dahms NM) Commun Biol 2020 Sep 09;3(1):498 PMID: 32908216 PMCID: PMC7481795 SCOPUS ID: 2-s2.0-85090384984 09/11/2020       18 Citations
  • Progress in the understanding and treatment of Fabry disease. (Miller JJ, Kanack AJ, Dahms NM) Biochim Biophys Acta Gen Subj 2020 Jan;1864(1):129437 PMID: 31526868 PMCID: PMC6981246 SCOPUS ID: 2-s2.0-85073720962 09/19/2019       68 Citations
  • Rats deficient in α-galactosidase A develop ocular manifestations of Fabry disease. (Miller JJ, Aoki K, Reid CA, Tiemeyer M, Dahms NM, Kassem IS) Sci Rep 2019 Jun 28;9(1):9392 PMID: 31253878 PMCID: PMC6599056 SCOPUS ID: 2-s2.0-85068107461 06/30/2019       7 Citations
  • α-Galactosidase A-deficient rats accumulate glycosphingolipids and develop cardiorenal phenotypes of Fabry disease. (Miller JJ, Aoki K, Mascari CA, Beltrame AK, Sokumbi O, North PE, Tiemeyer M, Kriegel AJ, Dahms NM) FASEB J 2019 Jan;33(1):418-429 PMID: 29979634 PMCID: PMC6629127 SCOPUS ID: 2-s2.0-85059237456 07/07/2018       20 Citations
  • Neuropathic pain in a Fabry disease rat model. (Miller JJ, Aoki K, Moehring F, Murphy CA, O'Hara CL, Tiemeyer M, Stucky CL, Dahms NM) JCI Insight 2018 Mar 22;3(6) PMID: 29563343 PMCID: PMC5926911 SCOPUS ID: 2-s2.0-85058370681 03/23/2018       42 Citations
  • Cation-Independent Mannose 6-Phosphate Receptor Deficiency Enhances β-Cell Susceptibility to Palmitate. (Baldwin AC, Naatz A, Bohnsack RN, Bartosiak JT, Oleson BJ, Hansen PA, Dahms NM, Corbett JA) Mol Cell Biol 2018 Apr 15;38(8) PMID: 29378831 PMCID: PMC5879465 SCOPUS ID: 2-s2.0-85044766344 01/31/2018       3 Citations
  • Cloning, Expression, and Purification of the Glycosylated Transmembrane Protein, Cation-Dependent Mannose 6-Phosphate Receptor, from Sf9 Cells Using the Baculovirus System. (Olson LJ, Dahms NM) Methods Mol Biol 2018;1722:105-116 PMID: 29264801 PMCID: PMC6202031 SCOPUS ID: 2-s2.0-85038831305 12/22/2017       2 Citations
  • Muscle targeting (Dahms NM) Biobetters: Protein Engineering to Approach the Curative August 21, 2015:23-40 SCOPUS ID: 2-s2.0-84958641251 08/21/2015    
  • Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition. (Olson LJ, Orsi R, Peterson FC, Parodi AJ, Kim JJ, D'Alessio C, Dahms NM) Biochemistry 2015 Jul 07;54(26):4097-111 PMID: 26062005 PMCID: PMC6202027 SCOPUS ID: 2-s2.0-84936769044 06/11/2015       14 Citations
  • Bacterial expression of the phosphodiester-binding site of the cation-independent mannose 6-phosphate receptor for crystallographic and NMR studies. (Olson LJ, Jensen DR, Volkman BF, Kim JJ, Peterson FC, Gundry RL, Dahms NM) Protein Expr Purif 2015 Jul;111:91-7 PMID: 25863146 PMCID: PMC4417374 SCOPUS ID: 2-s2.0-84927727743 04/12/2015       1 Citation
  • Glucosidase II and MRH-domain containing proteins in the secretory pathway. (D'Alessio C, Dahms NM) Curr Protein Pept Sci 2015;16(1):31-48 PMID: 25692846 PMCID: PMC4411176 SCOPUS ID: 2-s2.0-84930936566 02/19/2015       24 Citations
  • Identification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor. (Olson LJ, Castonguay AC, Lasanajak Y, Peterson FC, Cummings RD, Smith DF, Dahms NM) Glycobiology 2015 Jun;25(6):591-606 PMID: 25573276 PMCID: PMC4410830 SCOPUS ID: 2-s2.0-84930944628 01/13/2015       24 Citations
  • Mannose 6-Phosphate Receptors (Olson LJ, Dahms NM) Glycoscience: Biology and Medicine 1 January 2015:1037-1048 SCOPUS ID: 2-s2.0-84943616477 01/01/2015       2 Citations
  • Muscle targeting (Dahms NM) AAPS Advances in the Pharmaceutical Sciences Series 2015;19:23-40 SCOPUS ID: 2-s2.0-85080835832 01/01/2015    
  • Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. (Bohnsack RN, Warejcka DJ, Wang L, Gillespie SR, Bernstein AM, Twining SS, Dahms NM) Invest Ophthalmol Vis Sci 2014 Oct 30;55(12):7697-708 PMID: 25358730 PMCID: PMC4249949 SCOPUS ID: 2-s2.0-84914145905 11/02/2014       19 Citations
  • Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II, an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum. (Olson LJ, Orsi R, Alculumbre SG, Peterson FC, Stigliano ID, Parodi AJ, D'Alessio C, Dahms NM) J Biol Chem 2013 Jun 07;288(23):16460-16475 PMID: 23609449 PMCID: PMC3675582 SCOPUS ID: 2-s2.0-84878756888 04/24/2013       26 Citations
  • Glycosylation-independent lysosomal targeting of acid α-glucosidase enhances muscle glycogen clearance in pompe mice. (Maga JA, Zhou J, Kambampati R, Peng S, Wang X, Bohnsack RN, Thomm A, Golata S, Tom P, Dahms NM, Byrne BJ, LeBowitz JH) J Biol Chem 2013 Jan 18;288(3):1428-38 PMID: 23188827 PMCID: PMC3548456 SCOPUS ID: 2-s2.0-84872707665 11/29/2012       84 Citations
  • The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates. (Castonguay AC, Lasanajak Y, Song X, Olson LJ, Cummings RD, Smith DF, Dahms NM) Glycobiology 2012 Jul;22(7):983-96 PMID: 22369936 PMCID: PMC3355666 SCOPUS ID: 2-s2.0-84861409583 03/01/2012       17 Citations
  • Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and application in ligand identification of P-type lectins. (Song X, Heimburg-Molinaro J, Dahms NM, Smith DF, Cummings RD) Methods Mol Biol 2012;808:137-48 PMID: 22057522 PMCID: PMC4668285 SCOPUS ID: 2-s2.0-82355183891 11/08/2011       12 Citations
  • Mannose 6-phosphate receptor homology (MRH) domain-containing lectins in the secretory pathway. (Castonguay AC, Olson LJ, Dahms NM) Biochim Biophys Acta 2011 Sep;1810(9):815-26 PMID: 21723917 PMCID: PMC3150748 SCOPUS ID: 2-s2.0-79960702536 07/05/2011       26 Citations
  • Structural basis for recognition of phosphodiester-containing lysosomal enzymes by the cation-independent mannose 6-phosphate receptor. (Olson LJ, Peterson FC, Castonguay A, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Volkman BF, Dahms NM) Proc Natl Acad Sci U S A 2010 Jul 13;107(28):12493-8 PMID: 20615935 PMCID: PMC2906551 SCOPUS ID: 2-s2.0-77955444897 07/10/2010       38 Citations
  • Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptor. (Bohnsack RN, Patel M, Olson LJ, Twining SS, Dahms NM) Biochemistry 2010 Jan 26;49(3):635-44 PMID: 20028034 PMCID: PMC2814163 SCOPUS ID: 2-s2.0-74949084342 12/24/2009       11 Citations
  • Intermonomer interactions are essential for lysosomal enzyme binding by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Sun G, Bohnsack RN, Peterson FC, Dahms NM, Kim JJ) Biochemistry 2010 Jan 12;49(1):236-46 PMID: 19928875 PMCID: PMC2802658 SCOPUS ID: 2-s2.0-73449127633 11/26/2009       8 Citations
  • Cation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sites. (Bohnsack RN, Song X, Olson LJ, Kudo M, Gotschall RR, Canfield WM, Cummings RD, Smith DF, Dahms NM) J Biol Chem 2009 Dec 11;284(50):35215-26 PMID: 19840944 PMCID: PMC2787381 SCOPUS ID: 2-s2.0-71749085682 10/21/2009       57 Citations
  • Glycan microarray analysis of P-type lectins reveals distinct phosphomannose glycan recognition. (Song X, Lasanajak Y, Olson LJ, Boonen M, Dahms NM, Kornfeld S, Cummings RD, Smith DF) J Biol Chem 2009 Dec 11;284(50):35201-14 PMID: 19801653 PMCID: PMC2787380 SCOPUS ID: 2-s2.0-70349879814 10/06/2009       58 Citations
  • Carbohydrate recognition by the mannose-6-phosphate receptors. (Kim JJ, Olson LJ, Dahms NM) Curr Opin Struct Biol 2009 Oct;19(5):534-42 PMID: 19801188 PMCID: PMC2771201 SCOPUS ID: 2-s2.0-70349882101 10/06/2009       62 Citations
  • Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity. (Boonen M, Vogel P, Platt KA, Dahms N, Kornfeld S) Mol Biol Cell 2009 Oct;20(20):4381-9 PMID: 19710420 PMCID: PMC2762139 SCOPUS ID: 2-s2.0-70350094393 08/28/2009       24 Citations
  • Strategies for carbohydrate recognition by the mannose 6-phosphate receptors. (Dahms NM, Olson LJ, Kim JJ) Glycobiology 2008 Sep;18(9):664-78 PMID: 18621992 PMCID: PMC2733771 SCOPUS ID: 2-s2.0-58149107948 07/16/2008       86 Citations
  • P-type lectins and lysosomal enzyme trafficking (Marron-Terada PG, Dahms NM) Carbohydrates in Chemistry and Biology April 24, 2008;4-4:563-577 SCOPUS ID: 2-s2.0-84956524442 04/24/2008    
  • Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Hindsgaul O, Dahms NM, Kim JJ) J Biol Chem 2008 Apr 11;283(15):10124-34 PMID: 18272523 PMCID: PMC2442308 SCOPUS ID: 2-s2.0-44349171796 02/15/2008       30 Citations
  • P-Type Lectins and Lysosomal Enzyme Targeting (Dahms NM, Olson LJ, Kim JJP) Animal Lectins: A Functional View 1 January 2008:147-164 SCOPUS ID: 2-s2.0-85131992811 01/01/2008       1 Citation
  • Domain 5 of the cation-independent mannose 6-phosphate receptor preferentially binds phosphodiesters (mannose 6-phosphate N-acetylglucosamine ester). (Chavez CA, Bohnsack RN, Kudo M, Gotschall RR, Canfield WM, Dahms NM) Biochemistry 2007 Nov 06;46(44):12604-17 PMID: 17927214 SCOPUS ID: 2-s2.0-35848956125 10/12/2007       43 Citations
  • Identification of residues essential for carbohydrate recognition and cation dependence of the 46-kDa mannose 6-phosphate receptor. (Sun G, Zhao H, Kalyanaraman B, Dahms NM) Glycobiology 2005 Nov;15(11):1136-49 PMID: 15972892 SCOPUS ID: 2-s2.0-27944458451 06/24/2005       24 Citations
  • Identification of a low affinity mannose 6-phosphate-binding site in domain 5 of the cation-independent mannose 6-phosphate receptor. (Reddy ST, Chai W, Childs RA, Page JD, Feizi T, Dahms NM) J Biol Chem 2004 Sep 10;279(37):38658-67 PMID: 15252023 SCOPUS ID: 2-s2.0-4644360229 07/15/2004       60 Citations
  • The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor. (Olson LJ, Dahms NM, Kim JJ) J Biol Chem 2004 Aug 06;279(32):34000-9 PMID: 15169779 SCOPUS ID: 2-s2.0-4043147868 06/01/2004       50 Citations
  • Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor. (Olson LJ, Yammani RD, Dahms NM, Kim JJ) EMBO J 2004 May 19;23(10):2019-28 PMID: 15085180 PMCID: PMC424385 SCOPUS ID: 2-s2.0-2942558373 04/16/2004       55 Citations
  • Biochemical and functional properties of the full-length cation-dependent mannose 6-phosphate receptor expressed in Pichia pastoris. (Reddy ST, Kumar SN, Haas AL, Dahms NM) Biochem Biophys Res Commun 2003 Sep 26;309(3):643-51 PMID: 12963039 SCOPUS ID: 2-s2.0-0041328866 09/10/2003       7 Citations
  • Transcobalamin II receptor interacts with megalin in the renal apical brush border membrane. (Yammani RR, Seetharam S, Dahms NM, Seetharam B) J Membr Biol 2003 May 01;193(1):57-66 PMID: 12879166 SCOPUS ID: 2-s2.0-0041624141 07/25/2003       16 Citations
  • Mannose 6-phosphate receptors: new twists in the tale. (Ghosh P, Dahms NM, Kornfeld S) Nat Rev Mol Cell Biol 2003 Mar;4(3):202-12 PMID: 12612639 SCOPUS ID: 2-s2.0-0037336348 03/04/2003       857 Citations
  • High-level expression and characterization of a secreted recombinant cation-dependent mannose 6-phosphate receptor in Pichia pastoris. (Reddy ST, Dahms NM) Protein Expr Purif 2002 Nov;26(2):290-300 PMID: 12406684 SCOPUS ID: 2-s2.0-0036421312 10/31/2002       19 Citations
  • Localization of the carbohydrate recognition sites of the insulin-like growth factor II/mannose 6-phosphate receptor to domains 3 and 9 of the extracytoplasmic region. (Hancock MK, Yammani RD, Dahms NM) J Biol Chem 2002 Dec 06;277(49):47205-12 PMID: 12374794 SCOPUS ID: 2-s2.0-0037033019 10/11/2002       46 Citations
  • P-type lectins. (Dahms N, Hancock MK) Biochim Biophys Acta 2002 Sep 19;1572(2-3):317-40 PMID: 12223278 SCOPUS ID: 2-s2.0-0037136418 09/12/2002       191 Citations
  • Loss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiation. (Yammani RR, Sharma M, Seetharam S, Moulder JE, Dahms NM, Seetharam B) Am J Physiol Regul Integr Comp Physiol 2002 Aug;283(2):R339-46 PMID: 12121845 SCOPUS ID: 2-s2.0-0036340308 07/18/2002       23 Citations
  • Identification of residues essential for carbohydrate recognition by the insulin-like growth factor II/mannose 6-phosphate receptor. (Hancock MK, Haskins DJ, Sun G, Dahms NM) J Biol Chem 2002 Mar 29;277(13):11255-64 PMID: 11799115 SCOPUS ID: 2-s2.0-0037192762 01/19/2002       53 Citations
  • Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor. (Olson LJ, Zhang J, Dahms NM, Kim JJ) J Biol Chem 2002 Mar 22;277(12):10156-61 PMID: 11786557 SCOPUS ID: 2-s2.0-0037155883 01/12/2002       42 Citations
  • Basolateral sorting signal of the 300-kDa mannose 6-phosphate receptor. (Wick DA, Seetharam B, Dahms NM) Am J Physiol Gastrointest Liver Physiol 2002 Jan;282(1):G51-60 PMID: 11751157 SCOPUS ID: 2-s2.0-0036080409 12/26/2001       9 Citations
  • The cation-dependent mannose 6-phosphate receptor. (Kim JJ, Dahms NM) Results Probl Cell Differ 2001;33:39-56 PMID: 11190678 SCOPUS ID: 2-s2.0-0035227835 02/24/2001       8 Citations
  • Recognition of Dictyostelium discoideum lysosomal enzymes is conferred by the amino-terminal carbohydrate binding site of the insulin-like growth factor II/mannose 6-phosphate receptor. (Marron-Terada PG, Hancock MK, Haskins DJ, Dahms NM) Biochemistry 2000 Mar 07;39(9):2243-53 PMID: 10694390 SCOPUS ID: 2-s2.0-0034056050 03/01/2000       37 Citations
  • Mutational analysis of the binding site residues of the bovine cation-dependent mannose 6-phosphate receptor. (Olson LJ, Hancock MK, Dix D, Kim JJ, Dahms NM) J Biol Chem 1999 Dec 24;274(52):36905-11 PMID: 10601243 SCOPUS ID: 2-s2.0-0033601324 12/22/1999       29 Citations
  • Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Zhang J, Lee YC, Dahms NM, Kim JJ) J Biol Chem 1999 Oct 15;274(42):29889-96 PMID: 10514470 SCOPUS ID: 2-s2.0-0033569876 10/09/1999       56 Citations
  • Biosynthesis and secretion of the mannose 6-phosphate receptor and its ligands in polarized Caco-2 cells. (Wick DA, Seetharam B, Dahms NM) Am J Physiol 1999 Sep;277(3):G506-14 PMID: 10484374 SCOPUS ID: 2-s2.0-0032861253 09/14/1999       10 Citations
  • The rate of internalization of the mannose 6-phosphate/insulin-like growth factor II receptor is enhanced by multivalent ligand binding. (York SJ, Arneson LS, Gregory WT, Dahms NM, Kornfeld S) J Biol Chem 1999 Jan 08;274(2):1164-71 PMID: 9873065 SCOPUS ID: 2-s2.0-0033534489 01/05/1999       91 Citations
  • Characterization of truncated and glycosylation-deficient forms of the cation-dependent mannose 6-phosphate receptor expressed in baculovirus-infected insect cells. (Marron-Terada PG, Bollinger KE, Dahms NM) Biochemistry 1998 Dec 08;37(49):17223-9 PMID: 9860836 SCOPUS ID: 2-s2.0-0032497956 12/23/1998       20 Citations
  • The two mannose 6-phosphate binding sites of the insulin-like growth factor-II/mannose 6-phosphate receptor display different ligand binding properties. (Marron-Terada PG, Brzycki-Wessell MA, Dahms NM) J Biol Chem 1998 Aug 28;273(35):22358-66 PMID: 9712856 SCOPUS ID: 2-s2.0-0032575546 08/26/1998       27 Citations
  • Molecular basis of lysosomal enzyme recognition: three-dimensional structure of the cation-dependent mannose 6-phosphate receptor. (Roberts DL, Weix DJ, Dahms NM, Kim JJ) Cell 1998 May 15;93(4):639-48 PMID: 9604938 SCOPUS ID: 2-s2.0-0032524316 05/30/1998       106 Citations
  • Crystallization and structure determination of a functional bovine cation-dependent mannose 6-phosphate receptor (Roberts DL, Dahms NM, Kim JJP) FASEB Journal 1997;11(9) SCOPUS ID: 2-s2.0-33750234913 12/01/1997    
  • Inefficient targeting of lysosomal enzymes by mutant insulin-like growth factor ii/mannose 6-phosphate receptors (Marron-Terada PG, Brzvcki-Wessell MA, Dahms NM) FASEB Journal 1997;11(9) SCOPUS ID: 2-s2.0-33750133868 12/01/1997    
  • Bipolar functional expression of transcobalamin II receptor in human intestinal epithelial Caco-2 cells. (Bose S, Seetharam S, Dahms NM, Seetharam B) J Biol Chem 1997 Feb 07;272(6):3538-43 PMID: 9013602 SCOPUS ID: 2-s2.0-0031033885 02/07/1997       45 Citations
  • Insulin-like growth factor-II/mannose-6-phosphate receptor expression during early heart development. (McCormick KM, Dahms NM, Lough J) Dev Dyn 1996 Oct;207(2):195-203 PMID: 8906422 SCOPUS ID: 2-s2.0-0029853236 10/01/1996       8 Citations
  • Expression of insulin-like growth factor (IGF)-I receptors, IGF-II/cation-independent mannose 6-phosphate receptors (CI-MPRs), and cation-dependent MPRs in polarized human intestinal Caco-2 cells. (Dahms NM, Seetharam B, Wick DA) Biochim Biophys Acta 1996 Feb 21;1279(1):84-92 PMID: 8624366 SCOPUS ID: 2-s2.0-0030044859 02/21/1996       15 Citations
  • Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition. (Dahms NM) Biochem Soc Trans 1996 Feb;24(1):136-41 PMID: 8674625 SCOPUS ID: 2-s2.0-0030054287 02/01/1996       38 Citations
  • Expression of IGF-II and IGF binding proteins in differentiating human intestinal Caco-2 cells. (Zhang Y, Wick DA, Seetharam B, Dahms NM) Am J Physiol 1995 Nov;269(5 Pt 1):E804-13 PMID: 7491929 SCOPUS ID: 2-s2.0-0028841779 11/01/1995       29 Citations
  • Regulation of lysosomal and ubiquitin degradative pathways in differentiating human intestinal Caco-2 cells. (Zhang Y, Wick DA, Haas AL, Seetharam B, Dahms NM) Biochim Biophys Acta 1995 May 29;1267(1):15-24 PMID: 7540043 SCOPUS ID: 2-s2.0-0029018395 05/29/1995       11 Citations
  • Expression and characterization of functional bovine cation-dependent mannose 6-phosphate receptors in baculovirus-infected insect cells. (Dahms NM, Brzycki-Wessell MA) Arch Biochem Biophys 1995 Mar 10;317(2):497-503 PMID: 7893168 SCOPUS ID: 2-s2.0-0028929769 03/10/1995       9 Citations
  • Effect of processing inhibitors on cobalamin (vitamin B12) transcytosis in polarized opossum kidney cells. (Ramanujam KS, Seetharam S, Dahms NM, Seetharam B) Arch Biochem Biophys 1994 Nov 15;315(1):8-15 PMID: 7979409 SCOPUS ID: 2-s2.0-0027949405 11/15/1994       22 Citations
  • The bovine mannose 6-phosphate/insulin-like growth factor II receptor. Localization of the insulin-like growth factor II binding site to domains 5-11. (Dahms NM, Wick DA, Brzycki-Wessell MA) J Biol Chem 1994 Feb 04;269(5):3802-9 PMID: 8106425 SCOPUS ID: 2-s2.0-0028101930 02/04/1994       62 Citations
  • Site-directed removal of N-glycosylation sites in the bovine cation-dependent mannose 6-phosphate receptor: effects on ligand binding, intracellular targetting and association with binding immunoglobulin protein. (Zhang Y, Dahms NM) Biochem J 1993 Nov 01;295 ( Pt 3)(Pt 3):841-8 PMID: 8240300 PMCID: PMC1134638 SCOPUS ID: 2-s2.0-0027503915 11/01/1993       27 Citations
  • Characterization of mannose 6-phosphate receptors (MPRs) from opossum liver: opossum cation-independent MPR binds insulin-like growth factor-II. (Dahms NM, Brzycki-Wessell MA, Ramanujam KS, Seetharam B) Endocrinology 1993 Aug;133(2):440-6 PMID: 8344189 SCOPUS ID: 2-s2.0-0027317013 08/01/1993       36 Citations
  • The bovine mannose 6-phosphate/insulin-like growth factor II receptor. The role of arginine residues in mannose 6-phosphate binding. (Dahms NM, Rose PA, Molkentin JD, Zhang Y, Brzycki MA) J Biol Chem 1993 Mar 15;268(8):5457-63 PMID: 8449908 SCOPUS ID: 2-s2.0-0027471426 03/15/1993       94 Citations
  • Functional expression of transcobalamin II cDNA in Xenopus laevis oocytes. (Seetharam S, Dahms N, Li N, Seetharam B) Biochem Biophys Res Commun 1991 Dec 31;181(3):1151-5 PMID: 1764066 SCOPUS ID: 2-s2.0-0026357431 12/31/1991       8 Citations
  • The bovine mannose 6-phosphate/insulin-like growth factor II receptor. Localization of mannose 6-phosphate binding sites to domains 1-3 and 7-11 of the extracytoplasmic region. (Westlund B, Dahms NM, Kornfeld S) J Biol Chem 1991 Dec 05;266(34):23233-9 PMID: 1660469 SCOPUS ID: 2-s2.0-0026352780 12/05/1991       78 Citations
  • Functional expression of intrinsic factor-cobalamin receptor by renal proximal tubular epithelial cells. (Ramanujam KS, Seetharam S, Dahms NM, Seetharam B) J Biol Chem 1991 Jul 15;266(20):13135-40 PMID: 1649178 SCOPUS ID: 2-s2.0-0025873513 07/15/1991       29 Citations
  • In vitro translation and expression of renal intrinsic factor-cobalamin receptor. (Seetharam S, Dahms N, Li N, Ramanujam KS, Seetharam B) Biochem Biophys Res Commun 1991 Jun 14;177(2):751-6 PMID: 1646608 SCOPUS ID: 2-s2.0-0025816947 06/14/1991       4 Citations
  • Extracellular collagenase, proteoglycanase and products of their activity, released in organ culture by intact dermal inflammatory lesions produced by sulfur mustard. (Woessner JF Jr, Dannenberg AM Jr, Pula PJ, Selzer MG, Ruppert CL, Higuchi K, Kajiki A, Nakamura M, Dahms NM, Kerr JS) J Invest Dermatol 1990 Dec;95(6):717-26 PMID: 2174450 SCOPUS ID: 2-s2.0-0025613942 12/01/1990       31 Citations
  • Mannose 6-phosphate receptors and lysosomal enzyme targeting. (Dahms NM, Lobel P, Kornfeld S) J Biol Chem 1989 Jul 25;264(21):12115-8 PMID: 2545698 SCOPUS ID: 2-s2.0-0024364949 07/25/1989       425 Citations
  • The cation-dependent mannose 6-phosphate receptor. Structural requirements for mannose 6-phosphate binding and oligomerization. (Dahms NM, Kornfeld S) J Biol Chem 1989 Jul 05;264(19):11458-67 PMID: 2544594 SCOPUS ID: 2-s2.0-0024356196 07/05/1989       47 Citations
  • Cloning and sequence analysis of the cation-independent mannose 6-phosphate receptor. (Lobel P, Dahms NM, Kornfeld S) J Biol Chem 1988 Feb 15;263(5):2563-70 PMID: 2963004 SCOPUS ID: 2-s2.0-0023840372 02/15/1988       173 Citations
  • 46 kd mannose 6-phosphate receptor: cloning, expression, and homology to the 215 kd mannose 6-phosphate receptor. (Dahms NM, Lobel P, Breitmeyer J, Chirgwin JM, Kornfeld S) Cell 1987 Jul 17;50(2):181-92 PMID: 2954652 SCOPUS ID: 2-s2.0-0023658301 07/17/1987       112 Citations
  • Cloning of the bovine 215-kDa cation-independent mannose 6-phosphate receptor. (Lobel P, Dahms NM, Breitmeyer J, Chirgwin JM, Kornfeld S) Proc Natl Acad Sci U S A 1987 Apr;84(8):2233-7 PMID: 2951738 PMCID: PMC304623 SCOPUS ID: 2-s2.0-0023192368 04/01/1987       100 Citations
  • Influence of quaternary structure on glycosylation. Differential subunit association affects the site-specific glycosylation of the common beta-chain from Mac-1 and LFA-1. (Dahms NM, Hart GW) J Biol Chem 1986 Oct 05;261(28):13186-96 PMID: 3531197 SCOPUS ID: 2-s2.0-0022898398 10/05/1986       59 Citations
  • Lymphocyte function-associated antigen 1 (LFA-1) contains sulfated N-linked oligosaccharides. (Dahms NM, Hart GW) J Immunol 1985 Jun;134(6):3978-86 PMID: 3886793 SCOPUS ID: 2-s2.0-0021804195 06/01/1985       26 Citations
  • Ganglioside composition is regulated during differentiation in the neuroblastoma X glioma hybrid cell line NG108-15. (Dahms NM, Schnaar RL) J Neurosci 1983 Apr;3(4):806-17 PMID: 6300357 PMCID: PMC6564451 SCOPUS ID: 2-s2.0-0020519332 04/01/1983       62 Citations
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