Medical College of Wisconsin
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Lu Han PhD

Lu Han PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Cardiology

Member of the Cardiovascular Center

View Curriculum Vitae

Research Areas of Interest

  • Cardiology
  • Cell Differentiation
  • Induced Pluripotent Stem Cells
  • Mitosis
  • Myocytes, Cardiac

    • Publications (15)

  • Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration. (Auchampach J, Han L, Huang GN, Kühn B, Lough JW, O'Meara CC, Payumo AY, Rosenthal NA, Sucov HM, Yutzey KE, Patterson M) Am J Physiol Heart Circ Physiol 2022 Apr 01;322(4):H579-H596 PMID: 35179974 PMCID: PMC8934681 SCOPUS ID: 2-s2.0-85127729067 02/19/2022       17 Citations
  • Polyploid cardiomyocytes: implications for heart regeneration. (Kirillova A, Han L, Liu H, Kühn B) Development 2021 Jul 15;148(14) PMID: 34897388 PMCID: PMC8326922 SCOPUS ID: 2-s2.0-85112764604 12/14/2021       19 Citations
  • Generation of Human Induced Pluripotent Stem Cells and Differentiation into Cardiomyocytes. (Han L, Mich-Basso J, Kühn B) Methods Mol Biol 2021;2158:125-139 PMID: 32857370 PMCID: PMC8221246 SCOPUS ID: 2-s2.0-85090177829 08/29/2020       4 Citations
  • Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration. (Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JH, Wyman SK, Wu YL, Kühn B) Dev Cell 2020 Apr 06;53(1):42-59.e11 PMID: 32109383 PMCID: PMC7346764 SCOPUS ID: 2-s2.0-85082511708 02/29/2020       53 Citations
  • Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. (Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B) Sci Transl Med 2019 Oct 09;11(513) PMID: 31597755 PMCID: PMC8132604 SCOPUS ID: 2-s2.0-85073111294 10/11/2019       68 Citations
  • Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy. (Lin B, Li Y, Han L, Kaplan AD, Ao Y, Kalra S, Bett GC, Rasmusson RL, Denning C, Yang L) Dis Model Mech 2015 May;8(5):457-66 PMID: 25791035 PMCID: PMC4415895 SCOPUS ID: 2-s2.0-84928994904 03/21/2015       92 Citations
  • Reconciling computer models and stem cell models of human cardiac repolarization: reply. (Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L) Cardiovasc Res 2015 Apr 01;106(1):6-7 PMID: 25691542 SCOPUS ID: 2-s2.0-84926617108 02/19/2015    
  • Combined biophysical and soluble factor modulation induces cardiomyocyte differentiation from human muscle derived stem cells. (Tchao J, Han L, Lin B, Yang L, Tobita K) Sci Rep 2014 Oct 14;4:6614 PMID: 25310989 PMCID: PMC4196107 SCOPUS ID: 2-s2.0-84946867263 10/15/2014       11 Citations
  • Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells. (Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L) Cardiovasc Res 2014 Nov 01;104(2):258-69 PMID: 25209314 PMCID: PMC4217687 SCOPUS ID: 2-s2.0-84913590117 09/12/2014       141 Citations
  • Overexpression of microRNA-1 promotes cardiomyocyte commitment from human cardiovascular progenitors via suppressing WNT and FGF signaling pathways. (Lu TY, Lin B, Li Y, Arora A, Han L, Cui C, Coronnello C, Sheng Y, Benos PV, Yang L) J Mol Cell Cardiol 2013 Oct;63:146-54 PMID: 23939491 PMCID: PMC4268488 SCOPUS ID: 2-s2.0-84883118146 08/14/2013       56 Citations
  • Hydroxyurea-induced global transcriptional suppression in mouse ES cells. (Cui P, Lin Q, Xin C, Han L, An L, Wang Y, Hu Z, Ding F, Zhang L, Hu S, Hang H, Yu J) Carcinogenesis 2010 Sep;31(9):1661-8 PMID: 20513671 SCOPUS ID: 2-s2.0-77956283059 06/02/2010       11 Citations
  • Mouse Rad1 deletion enhances susceptibility for skin tumor development. (Han L, Hu Z, Liu Y, Wang X, Hopkins KM, Lieberman HB, Hang H) Mol Cancer 2010 Mar 24;9:67 PMID: 20334655 PMCID: PMC2864214 SCOPUS ID: 2-s2.0-77952656146 03/26/2010       31 Citations
  • Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1. (He W, Zhao Y, Zhang C, An L, Hu Z, Liu Y, Han L, Bi L, Xie Z, Xue P, Yang F, Hang H) Nucleic Acids Res 2008 Nov;36(20):6406-17 PMID: 18842633 PMCID: PMC2582629 SCOPUS ID: 2-s2.0-56649117678 10/10/2008       41 Citations
  • Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development. (Hu Z, Liu Y, Zhang C, Zhao Y, He W, Han L, Yang L, Hopkins KM, Yang X, Lieberman HB, Hang H) Cancer Res 2008 Jul 15;68(14):5552-61 PMID: 18632607 PMCID: PMC4331354 SCOPUS ID: 2-s2.0-48649106833 07/18/2008       30 Citations
  • Alteration in levels of immunoreactive epidermal growth factor in the gastrointestinal mucosa of Fischer rats fed a diet containing 10% wheat bran. (Schaudies RP, Satchithanandam S, Calvert RJ) J Nutr 1991 Jun;121(6):800-5 PMID: 2033465 SCOPUS ID: 2-s2.0-0025864143 06/01/1991       5 Citations
    • Last update: 10/27/2023