Medical College of Wisconsin
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Melanie Gartz PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration

image of /images/ORCIDiD_icon16x16.png   https://orcid.org/0000-0001-8117-0906


I am willing to collaborate on research projects.
I am willing to mentor a junior faculty member.


Publications (14)

  • ACTA1 H40Y mutant iPSC-derived skeletal myocytes display mitochondrial defects in an in vitro model of nemaline myopathy. (Gartz M, Haberman M, Sutton J, Slick RA, Luttrell SM, Mack DL, Lawlor MW) Exp Cell Res 2023 Mar 15;424(2):113507 PMID: 36796746 PMCID: PMC9993434 SCOPUS ID: 2-s2.0-85149427969 02/17/2023       2 Citations
  • A Long-Term Study Evaluating the Effects of Nicorandil Treatment on Duchenne Muscular Dystrophy-Associated Cardiomyopathy in mdx Mice. (Gartz M, Haberman M, Prom MJ, Beatka MJ, Strande JL, Lawlor MW) J Cardiovasc Pharmacol Ther 2022;27:10742484221088655 PMID: 35353647 SCOPUS ID: 2-s2.0-85127284016 03/31/2022    
  • Optimizing the Differentiation of Cardiomyocytes from Human Induced Pluripotent-Derived Stem Cells. (Gartz M, Strande JL) Methods Mol Biol 2021;2319:51-60 PMID: 34331242 SCOPUS ID: 2-s2.0-85112650897 08/01/2021    
  • Cardiomyocyte-produced miR-339-5p mediates pathology in Duchenne muscular dystrophy cardiomyopathy. (Gartz M, Beatka M, Prom MJ, Strande JL, Lawlor MW) Hum Mol Genet 2021 Nov 16;30(23):2347-2361 PMID: 34270708 PMCID: PMC8600005 SCOPUS ID: 2-s2.0-85121129104 07/17/2021       7 Citations
  • Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy. (Gartz M, Lin CW, Sussman MA, Lawlor MW, Strande JL) Dis Model Mech 2020 Nov 13;13(11) PMID: 33188007 PMCID: PMC7673361 SCOPUS ID: 2-s2.0-85096154674 11/15/2020       19 Citations
  • First person - Melanie Gartz (Gartz M) DMM Disease Models and Mechanisms November 2020;13(11) SCOPUS ID: 2-s2.0-85096878827 11/01/2020    
  • Influence of microRNAs and exosomes in muscle health and diseases. (Lam NT, Gartz M, Thomas L, Haberman M, Strande JL) J Muscle Res Cell Motil 2020 Dec;41(4):269-284 PMID: 31564031 PMCID: PMC7101267 SCOPUS ID: 2-s2.0-85073991345 09/30/2019       12 Citations
  • Exosomes exert cardioprotection in dystrophin-deficient cardiomyocytes via ERK1/2-p38/MAPK signaling. (Gartz M, Darlington A, Afzal MZ, Strande JL) Sci Rep 2018 Nov 08;8(1):16519 PMID: 30410044 PMCID: PMC6224575 SCOPUS ID: 2-s2.0-85056282822 11/10/2018       32 Citations
  • Examining the Paracrine Effects of Exosomes in Cardiovascular Disease and Repair. (Gartz M, Strande JL) J Am Heart Assoc 2018 Jun 01;7(11) PMID: 29858362 PMCID: PMC6015376 SCOPUS ID: 2-s2.0-85048024676 06/03/2018       68 Citations
  • Generation of human iPSCs from urine derived cells of patient with a novel heterozygous PAI-1 mutation. (Afzal MZ, Gartz M, Klyachko EA, Khan SS, Shah SJ, Gupta S, Shapiro AD, Vaughan DE, Strande JL) Stem Cell Res 2017 Jan;18:41-44 PMID: 28395801 PMCID: PMC5939958 SCOPUS ID: 2-s2.0-85028072477 04/12/2017       6 Citations
  • Generation of human iPSCs from urine derived cells of a non-affected control subject. (Afzal MZ, Gartz M, Klyachko EA, Khan SS, Shah SJ, Gupta S, Shapiro AD, Vaughan DE, Strande JL) Stem Cell Res 2017 Jan;18:33-36 PMID: 28395799 PMCID: PMC5389122 SCOPUS ID: 2-s2.0-85028089891 04/12/2017       7 Citations
  • Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes. (Kriegel AJ, Gartz M, Afzal MZ, de Lange WJ, Ralphe JC, Strande JL) J Cardiovasc Transl Res 2017 Jun;10(3):295-304 PMID: 28032312 PMCID: PMC5937699 SCOPUS ID: 2-s2.0-85007413634 12/30/2016       9 Citations
  • Generation of human iPSCs from urine derived cells of a patient with a novel homozygous PAI-1 mutation. (Afzal MZ, Gartz M, Klyachko EA, Khan SS, Shah SJ, Gupta S, Shapiro AD, Vaughan DE, Strande JL) Stem Cell Res 2016 Nov;17(3):657-660 PMID: 27934602 PMCID: PMC5409870 SCOPUS ID: 2-s2.0-85028043697 12/10/2016       3 Citations
  • Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy (Muhammad Z Afzal, Melanie Reiter, Courtney Gastonguay, Jered V McGivern, Xuan Guan, Zhi-Dong Ge, David L Mack, Martin K Childers, Allison D Ebert, Jennifer L Strande) J Cardiovasc Pharmacol Ther Afzal MZ, Reiter M, Gastonguay C, McGivern JV, Guan X, Ge ZD, Mack DL, Childers MK, Ebert AD, Strande JL. Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy. J Cardiovasc Pharmacol Ther. 2016 Nov;21(6):549-562. doi: 10.1177/1074248416636477. Epub 2016 Mar 2. PMID: 26940570; PMCID: PMC5010518. 03/02/2016    
  • Last update: 03/20/2023