Medical College of Wisconsin
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Ulrich Broeckel MD

Chief, Center Associate Director, Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Genomic Pediatrics
Program: Genomic Pediatrics

Member of the Cardiovascular Center


Leadership Positions

  • Chief - Section of Genomic Pediatrics, Department of Pediatrics
    Director, Individualized Medicine Institute, MCW
    Associate Director , Children's Research Institute
  • MCW Program / Core Facilities

  • Co-Director, Nucleic Acid Extraction Core.
  • Publications

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. (Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, Liu Y, Liu Y, Lu Y, Nalls MA, Sun YV, Wojczynski MK, Yanek LR, Aldrich MC, Ademola A, Amos CI, Bandera EV, Bock CH, Britton A, Broeckel U, Cai Q, Caporaso NE, Carlson CS, Carpten J, Casey G, Chen WM, Chen F, Chen YD, Chiang CW, Coetzee GA, Demerath E, Deming-Halverson SL, Driver RW, Dubbert P, Feitosa MF, Feng Y, Freedman BI, Gillanders EM, Gottesman O, Guo X, Haritunians T, Harris T, Harris CC, Hennis AJ, Hernandez DG, McNeill LH, Howard TD, Howard BV, Howard VJ, Johnson KC, Kang SJ, Keating BJ, Kolb S, Kuller LH, Kutlar A, Langefeld CD, Lettre G, Lohman K, Lotay V, Lyon H, Manson JE, Maixner W, Meng YA, Monroe KR, Morhason-Bello I, Murphy AB, Mychaleckyj JC, Nadukuru R, Nathanson KL, Nayak U, N'diaye A, Nemesure B, Wu SY, Leske MC, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran TO, Ojengbede O, Olopade OI, Palmer JR, Ruiz-Narvaez EA, Palmer ND, Press MF, Rampersaud E, Rasmussen-Torvik LJ, Rodriguez-Gil JL, Salako B, Schadt EE, Schwartz AG, Shriner DA, Siscovick D, Smith SB, Wassertheil-Smoller S, Speliotes EK, Spitz MR, Sucheston L, Taylor H, Tayo BO, Tucker MA, Van Den Berg DJ, Edwards DR, Wang Z, Wiencke JK, Winkler TW, Witte JS, Wrensch M, Wu X, Yang JJ, Levin AM, Young TR, Zakai NA, Cushman M, Zanetti KA, Zhao JH, Zhao W, Zheng Y, Zhou J, Ziegler RG, Zmuda JM, Fernandes JK, Gilkeson GS, Kamen DL, Hunt KJ, Spruill IJ, Ambrosone CB, Ambs S, Arnett DK, Atwood L, Becker DM, Berndt SI, Bernstein L, Blot WJ, Borecki IB, Bottinger EP, Bowden DW, Burke G, Chanock SJ, Cooper RS, Ding J, Duggan D, Evans MK, Fox C, Garvey WT, Bradfield JP, Hakonarson H, Grant SF, Hsing A, Chu L, Hu JJ, Huo D, Ingles SA, John EM, Jordan JM, Kabagambe EK, Kardia SL, Kittles RA, Goodman PJ, Klein EA, Kolonel LN, Le Marchand L, Liu S, McKnight B, Millikan RC, Mosley TH, Padhukasahasram B, Williams LK, Patel SR, Peters U, Pettaway CA, Peyser PA, Psaty BM, Redline S, Rotimi CN, Rybicki BA, Sale MM, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Strom SS, Thun MJ, Vitolins M, Zheng W, Moore JH, Williams SM, Ketkar S, Zhu X, Zonderman AB, NABEC Consortium, UKBEC Consortium, BioBank Japan Project, AGEN Consortium, Kooperberg C, Papanicolaou GJ, Henderson BE, Reiner AP, Hirschhorn JN, Loos RJ, North KE, Haiman CA) Nat Genet 2013 Jun;45(6):690-6 PMID: 23583978 PMCID: PMC3694490 04/16/2013
  • QTL-based association analyses reveal novel genes influencing pleiotropy of metabolic syndrome (MetS). (Zhang Y, Kent JW Jr, Olivier M, Ali O, Broeckel U, Abdou RM, Dyer TD, Comuzzie A, Curran JE, Carless MA, Rainwater DL, Göring HH, Blangero J, Kissebah AH) Obesity (Silver Spring) 2013 Oct;21(10):2099-111 PMID: 23418049 PMCID: PMC3769476 02/19/2013
  • IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy. (Schmitt EG, Haribhai D, Williams JB, Aggarwal P, Jia S, Charbonnier LM, Yan K, Lorier R, Turner A, Ziegelbauer J, Georgiev P, Simpson P, Salzman NH, Hessner MJ, Broeckel U, Chatila TA, Williams CB) J Immunol 2012 Dec 15;189(12):5638-48 PMID: 23125413 PMCID: PMC3537488 11/06/2012
  • Copy number variation analysis in 98 individuals with PHACE syndrome. (Siegel DH, Shieh JT, Kwon EK, Baselga E, Blei F, Cordisco M, Dobyns WB, Duffy KJ, Garzon MC, Gibbs DL, Grimmer JF, Hayflick SJ, Krol AL, Kwok PY, Lorier R, Matter A, McWeeney S, Metry D, Mitchell S, Pope E, Santoro JL, Stevenson DA, Bayrak-Toydemir P, Wilmot B, Worthey EA, Frieden IJ, Drolet BA, Broeckel U) J Invest Dermatol 2013 Mar;133(3):677-84 PMID: 23096700 PMCID: PMC3971866 10/26/2012
  • Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. (Mangino M, Hwang SJ, Spector TD, Hunt SC, Kimura M, Fitzpatrick AL, Christiansen L, Petersen I, Elbers CC, Harris T, Chen W, Srinivasan SR, Kark JD, Benetos A, El Shamieh S, Visvikis-Siest S, Christensen K, Berenson GS, Valdes AM, Viñuela A, Garcia M, Arnett DK, Broeckel U, Province MA, Pankow JS, Kammerer C, Liu Y, Nalls M, Tishkoff S, Thomas F, Ziv E, Psaty BM, Bis JC, Rotter JI, Taylor KD, Smith E, Schork NJ, Levy D, Aviv A) Hum Mol Genet 2012 Dec 15;21(24):5385-94 PMID: 23001564 PMCID: PMC3510758 09/25/2012
  • A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. (Hicks JK, Crews KR, Hoffman JM, Kornegay NM, Wilkinson MR, Lorier R, Stoddard A, Yang W, Smith C, Fernandez CA, Cross SJ, Haidar C, Baker DK, Howard SC, Evans WE, Broeckel U, Relling MV) Clin Pharmacol Ther 2012 Nov;92(5):563-6 PMID: 22990750 PMCID: PMC3589522 09/20/2012
  • Concordance of DMET plus genotyping results with those of orthogonal genotyping methods. (Fernandez CA, Smith C, Yang W, Lorier R, Crews KR, Kornegay N, Hicks JK, Stewart CF, Kawedia JD, Ramsey LB, Liu C, Evans WE, Relling MV, Broeckel U) Clin Pharmacol Ther 2012 Sep;92(3):360-5 PMID: 22871999 PMCID: PMC3516299 08/09/2012
  • Copy number variations associated with obesity-related traits in African Americans: a joint analysis between GENOA and HyperGEN. (Zhao W, Wineinger NE, Tiwari HK, Mosley TH, Broeckel U, Arnett DK, Kardia SL, Kabagambe EK, Sun YV) Obesity (Silver Spring) 2012 Dec;20(12):2431-7 PMID: 22836685 PMCID: PMC3484176 07/28/2012
  • Genome-wide meta-analyses of smoking behaviors in African Americans. (David SP, Hamidovic A, Chen GK, Bergen AW, Wessel J, Kasberger JL, Brown WM, Petruzella S, Thacker EL, Kim Y, Nalls MA, Tranah GJ, Sung YJ, Ambrosone CB, Arnett D, Bandera EV, Becker DM, Becker L, Berndt SI, Bernstein L, Blot WJ, Broeckel U, Buxbaum SG, Caporaso N, Casey G, Chanock SJ, Deming SL, Diver WR, Eaton CB, Evans DS, Evans MK, Fornage M, Franceschini N, Harris TB, Henderson BE, Hernandez DG, Hitsman B, Hu JJ, Hunt SC, Ingles SA, John EM, Kittles R, Kolb S, Kolonel LN, Le Marchand L, Liu Y, Lohman KK, McKnight B, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press M, Psaty BM, Rao DC, Redline S, Rodriguez-Gil JL, Rybicki BA, Signorello LB, Singleton AB, Smoller J, Snively B, Spring B, Stanford JL, Strom SS, Swan GE, Taylor KD, Thun MJ, Wilson AF, Witte JS, Yamamura Y, Yanek LR, Yu K, Zheng W, Ziegler RG, Zonderman AB, Jorgenson E, Haiman CA, Furberg H) Transl Psychiatry 2012 May 22;2:e119 PMID: 22832964 PMCID: PMC3365260 07/27/2012
  • Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophy. (Zhi D, Irvin MR, Gu CC, Stoddard AJ, Lorier R, Matter A, Rao DC, Srinivasasainagendra V, Tiwari HK, Turner A, Broeckel U, Arnett DK) Front Genet 2012;3:92 PMID: 22654895 PMCID: PMC3361011 06/02/2012
  • Genotype imputation for African Americans using data from HapMap phase II versus 1000 genomes projects. (Sung YJ, Gu CC, Tiwari HK, Arnett DK, Broeckel U, Rao DC) Genet Epidemiol 2012 Jul;36(5):508-16 PMID: 22644746 PMCID: PMC3703942 05/31/2012
  • PITX2 and FOXC1 spectrum of mutations in ocular syndromes. (Reis LM, Tyler RC, Volkmann Kloss BA, Schilter KF, Levin AV, Lowry RB, Zwijnenburg PJ, Stroh E, Broeckel U, Murray JC, Semina EV) Eur J Hum Genet 2012 Dec;20(12):1224-33 PMID: 22569110 PMCID: PMC3499749 05/10/2012
  • Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice. (Kraja AT, Lawson HA, Arnett DK, Borecki IB, Broeckel U, de las Fuentes L, Hunt SC, Province MA, Cheverud J, Rao DC) Metabolism 2012 Aug;61(8):1129-41 PMID: 22386932 PMCID: PMC3586585 03/06/2012
  • Human gene copy number spectra analysis in congenital heart malformations. (Tomita-Mitchell A, Mahnke DK, Struble CA, Tuffnell ME, Stamm KD, Hidestrand M, Harris SE, Goetsch MA, Simpson PM, Bick DP, Broeckel U, Pelech AN, Tweddell JS, Mitchell ME) Physiol Genomics 2012 May 01;44(9):518-41 PMID: 22318994 PMCID: PMC3426426 02/10/2012
  • Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. (Maloney JP, Stearman RS, Bull TM, Calabrese DW, Tripp-Addison ML, Wick MJ, Broeckel U, Robbins IM, Wheeler LA, Cogan JD, Loyd JE) Am J Physiol Lung Cell Mol Physiol 2012 Mar 15;302(6):L541-54 PMID: 22198906 PMCID: PMC3311532 12/27/2011
  • Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat chloride levels and pancreatic sufficiency. (Sebro R, Levy H, Schneck K, Dimmock D, Raby BA, Cannon CL, Broeckel U, Risch NJ) Clin Genet 2012 Dec;82(6):546-51 PMID: 22035343 PMCID: PMC4279028 11/01/2011
  • Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. (Irvin MR, Wineinger NE, Rice TK, Pajewski NM, Kabagambe EK, Gu CC, Pankow J, North KE, Wilk JB, Freedman BI, Franceschini N, Broeckel U, Tiwari HK, Arnett DK) PLoS One 2011;6(8):e24052 PMID: 21901158 PMCID: PMC3162025 09/09/2011
  • Variants on chromosome 6p22.3 associated with blood pressure in the HyperGEN study: follow-up of FBPP quantitative trait loci. (Simino J, Shi G, Arnett D, Broeckel U, Hunt SC, Rao DC) Am J Hypertens 2011 Nov;24(11):1227-33 PMID: 21850057 PMCID: PMC3406604 08/19/2011
  • Characterization of autosomal copy-number variation in African Americans: the HyperGEN Study. (Wineinger NE, Pajewski NM, Kennedy RE, Wojczynski MK, Vaughan LK, Hunt SC, Gu CC, Rao DC, Lorier R, Broeckel U, Arnett DK, Tiwari HK) Eur J Hum Genet 2011 Dec;19(12):1271-5 PMID: 21673747 PMCID: PMC3230358 06/16/2011
  • BMP4 loss-of-function mutations in developmental eye disorders including SHORT syndrome. (Reis LM, Tyler RC, Schilter KF, Abdul-Rahman O, Innis JW, Kozel BA, Schneider AS, Bardakjian TM, Lose EJ, Martin DM, Broeckel U, Semina EV) Hum Genet 2011 Oct;130(4):495-504 PMID: 21340693 PMCID: PMC3178759 02/23/2011
  • The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease. (Däbritz J, Friedrichs F, Weinhage T, Hampe J, Kucharzik T, Lügering A, Broeckel U, Schreiber S, Spieker T, Stoll M, Foell D) Am J Physiol Gastrointest Liver Physiol 2011 May;300(5):G823-32 PMID: 21311028 02/12/2011
  • Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study. (Wineinger NE, Patki A, Meyers KJ, Broeckel U, Gu CC, Rao DC, Devereux RB, Arnett DK, Tiwari HK) BMC Med Genomics 2011 Jan 11;4:4 PMID: 21223598 PMCID: PMC3027088 01/13/2011
  • Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families. (Arnett DK, Meyers KJ, Devereux RB, Tiwari HK, Gu CC, Vaughan LK, Perry RT, Patki A, Claas SA, Sun YV, Broeckel U, Kardia SL) Circ Res 2011 Feb 04;108(3):279-83 PMID: 21212386 PMCID: PMC3328104 01/08/2011
  • The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation. (Broeckel U, Stoll M, Hein L) Curr Opin Nephrol Hypertens 2011 Mar;20(2):118-24 PMID: 21191291 12/31/2010
  • Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease. (Worthey EA, Mayer AN, Syverson GD, Helbling D, Bonacci BB, Decker B, Serpe JM, Dasu T, Tschannen MR, Veith RL, Basehore MJ, Broeckel U, Tomita-Mitchell A, Arca MJ, Casper JT, Margolis DA, Bick DP, Hessner MJ, Routes JM, Verbsky JW, Jacob HJ, Dimmock DP) Genet Med 2011 Mar;13(3):255-62 PMID: 21173700 12/22/2010
  • Potential novel mechanism for Axenfeld-Rieger syndrome: deletion of a distant region containing regulatory elements of PITX2. (Volkmann BA, Zinkevich NS, Mustonen A, Schilter KF, Bosenko DV, Reis LM, Broeckel U, Link BA, Semina EV) Invest Ophthalmol Vis Sci 2011 Mar;52(3):1450-9 PMID: 20881290 PMCID: PMC3101680 10/01/2010
  • Bivariate genetic association of KIAA1797 with heart rate in American Indians: the Strong Heart Family Study. (Melton PE, Rutherford S, Voruganti VS, Göring HH, Laston S, Haack K, Comuzzie AG, Dyer TD, Johnson MP, Kent JW Jr, Curran JE, Moses EK, Blangero J, Barac A, Lee ET, Best LG, Fabsitz RR, Devereux RB, Okin PM, Bella JN, Broeckel U, Howard BV, MacCluer JW, Cole SA, Almasy L) Hum Mol Genet 2010 Sep 15;19(18):3662-71 PMID: 20601674 PMCID: PMC2928129 07/06/2010
  • Multiplexed quantitative real-time PCR to detect 22q11.2 deletion in patients with congenital heart disease. (Tomita-Mitchell A, Mahnke DK, Larson JM, Ghanta S, Feng Y, Simpson PM, Broeckel U, Duffy K, Tweddell JS, Grossman WJ, Routes JM, Mitchell ME) Physiol Genomics 2010 Sep;42A(1):52-60 PMID: 20551144 PMCID: PMC2957771 06/17/2010
  • Adducin 1 (alpha) Gly460Trp variant is associated with left ventricular geometry in Caucasians and African Americans: The HyperGEN Study. (Chauhan K, Devereux RB, Rao D, Broeckel U, Gu CC, Hopkins P, Arnett DK) Int J Mol Epidemiol Genet 2010 Feb 26;1(4):367-76 PMID: 21532846 PMCID: PMC3076776 01/01/2010
  • Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. (Beetz N, Harrison MD, Brede M, Zong X, Urbanski MJ, Sietmann A, Kaufling J, Lorkowski S, Barrot M, Seeliger MW, Vieira-Coelho MA, Hamet P, Gaudet D, Seda O, Tremblay J, Kotchen TA, Kaldunski M, Nüsing R, Szabo B, Jacob HJ, Cowley AW Jr, Biel M, Stoll M, Lohse MJ, Broeckel U, Hein L) J Clin Invest 2009 Dec;119(12):3597-3612 PMID: 19959875 PMCID: PMC2786789 12/05/2009
  • Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study. (Arnett DK, Devereux RB, Rao DC, Li N, Tang W, Kraemer R, Claas SA, Leon JM, Broeckel U) J Hypertens 2009 Aug;27(8):1585-93 PMID: 19593212 PMCID: PMC2868312 07/14/2009
  • An autoinflammatory disease due to homozygous deletion of the IL1RN locus. (Reddy S, Jia S, Geoffrey R, Lorier R, Suchi M, Broeckel U, Hessner MJ, Verbsky J) N Engl J Med 2009 Jun 04;360(23):2438-44 PMID: 19494219 PMCID: PMC2803085 06/06/2009
  • Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study. (Arnett DK, Li N, Tang W, Rao DC, Devereux RB, Claas SA, Kraemer R, Broeckel U) BMC Med Genet 2009 May 19;10:43 PMID: 19454037 PMCID: PMC2692849 05/21/2009
  • The role of genomics in the neonatal ICU. (Maresso K, Broeckel U) Clin Perinatol 2009 Mar;36(1):189-204 PMID: 19161875 01/24/2009
  • Genetic determinants of hypertension: an update. (Harrison M, Maresso K, Broeckel U) Curr Hypertens Rep 2008 Dec;10(6):488-95 PMID: 18959837 10/31/2008
  • Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans. (Maresso K, Broeckel U) Adv Genet 2008;60:107-39 PMID: 18358318 03/25/2008
  • Pediatric onset Crohn's colitis is characterized by genotype-dependent age-related susceptibility. (Levine A, Kugathasan S, Annese V, Biank V, Leshinsky-Silver E, Davidovich O, Kimmel G, Shamir R, Palmieri O, Karban A, Broeckel U, Cucchiara S) Inflamm Bowel Dis 2007 Dec;13(12):1509-15 PMID: 17763471 09/01/2007
  • Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man. (Luchtefeld M, Schunkert H, Stoll M, Selle T, Lorier R, Grote K, Sagebiel C, Jagavelu K, Tietge UJ, Assmus U, Streetz K, Hengstenberg C, Fischer M, Mayer B, Maresso K, El Mokhtari NE, Schreiber S, Müller W, Bavendiek U, Grothusen C, Drexler H, Trautwein C, Broeckel U, Schieffer B) J Exp Med 2007 Aug 06;204(8):1935-44 PMID: 17664290 PMCID: PMC2118681 08/01/2007
  • Pediatric inflammatory bowel disease: clinical and molecular genetics. (Biank V, Broeckel U, Kugathasan S) Inflamm Bowel Dis 2007 Nov;13(11):1430-8 PMID: 17600381 06/30/2007
  • A locus on chromosome 10 influences C-reactive protein levels in two independent populations. (Broeckel U, Hengstenberg C, Mayer B, Maresso K, Gaudet D, Seda O, Tremblay J, Holmer S, Erdmann J, Glöckner C, Harrison M, Martin LJ, Williams JT, Schmitz G, Riegger GA, Jacob HJ, Hamet P, Schunkert H) Hum Genet 2007 Aug;122(1):95-102 PMID: 17530289 05/29/2007
  • Lymphotoxin-alpha and galectin-2 SNPs are not associated with myocardial infarction in two different German populations. (Sedlacek K, Neureuther K, Mueller JC, Stark K, Fischer M, Baessler A, Reinhard W, Broeckel U, Lieb W, Erdmann J, Schunkert H, Riegger G, Illig T, Meitinger T, Hengstenberg C) J Mol Med (Berl) 2007 Sep;85(9):997-1004 PMID: 17497114 05/15/2007
  • DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease. (Biank V, Friedrichs F, Babusukumar U, Wang T, Stoll M, Broeckel U, Kugathasan S) Am J Gastroenterol 2007 Feb;102(2):391-8 PMID: 17156146 12/13/2006
  • Linkage analysis for complex diseases using variance component analysis: SOLAR. (Broeckel U, Maresso K, Martin LJ) Methods Mol Med 2006;128:91-100 PMID: 17071991 10/31/2006
  • Functional genomics and its implications for molecular medicine. (Broeckel U, Maresso K, Kugathasan S) Pediatr Clin North Am 2006 Oct;53(5):807-16, vii PMID: 17027611 10/10/2006
  • Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease. (Babusukumar U, Wang T, McGuire E, Broeckel U, Kugathasan S) Am J Gastroenterol 2006 Jun;101(6):1354-61 PMID: 16771961 06/15/2006
  • Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men. (Friedrichs F, Brescianini S, Annese V, Latiano A, Berger K, Kugathasan S, Broeckel U, Nikolaus S, Daly MJ, Schreiber S, Rioux JD, Stoll M) Hum Genet 2006 Apr;119(3):305-11 PMID: 16446977 02/01/2006
  • Toward the etiologies of congenital heart diseases. (Pelech AN, Broeckel U) Clin Perinatol 2005 Dec;32(4):825-44, vii PMID: 16325664 12/06/2005
  • Epidemiology, risk factors, and genetics of high-altitude-related pulmonary disease. (Maloney JP, Broeckel U) Clin Chest Med 2005 Sep;26(3):395-404, v PMID: 16140134 09/06/2005
  • Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease. (Kugathasan S, Loizides A, Babusukumar U, McGuire E, Wang T, Hooper P, Nebel J, Kofman G, Noel R, Broeckel U, Tolia V) Inflamm Bowel Dis 2005 Jul;11(7):631-8 PMID: 15973116 06/24/2005
  • Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. (Hamet P, Merlo E, Seda O, Broeckel U, Tremblay J, Kaldunski M, Gaudet D, Bouchard G, Deslauriers B, Gagnon F, Antoniol G, Pausová Z, Labuda M, Jomphe M, Gossard F, Tremblay G, Kirova R, Tonellato P, Orlov SN, Pintos J, Platko J, Hudson TJ, Rioux JD, Kotchen TA, Cowley AW Jr) Am J Hum Genet 2005 May;76(5):815-32 PMID: 15800845 PMCID: PMC1199371 04/01/2005
  • Distinct heritable patterns of angiographic coronary artery disease in families with myocardial infarction. (Fischer M, Broeckel U, Holmer S, Baessler A, Hengstenberg C, Mayer B, Erdmann J, Klein G, Riegger G, Jacob HJ, Schunkert H) Circulation 2005 Feb 22;111(7):855-62 PMID: 15710764 02/16/2005
  • CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease. (Kugathasan S, Collins N, Maresso K, Hoffmann RG, Stephens M, Werlin SL, Rudolph C, Broeckel U) Clin Gastroenterol Hepatol 2004 Nov;2(11):1003-9 PMID: 15551253 11/20/2004
  • Genes for left ventricular hypertrophy. (Arnett DK, de las Fuentes L, Broeckel U) Curr Hypertens Rep 2004 Feb;6(1):36-41 PMID: 14972088 02/20/2004
  • Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping. (Broeckel U, Schork NJ) J Physiol 2004 Jan 01;554(Pt 1):40-5 PMID: 14678489 PMCID: PMC1664744 12/18/2003
  • Prevalence of left ventricular diastolic dysfunction in the community. Results from a Doppler echocardiographic-based survey of a population sample. (Fischer M, Baessler A, Hense HW, Hengstenberg C, Muscholl M, Holmer S, Döring A, Broeckel U, Riegger G, Schunkert H) Eur Heart J 2003 Feb;24(4):320-8 PMID: 12581679 02/13/2003
  • Identification of hypertension-related QTLs in African American sib pairs. (Kotchen TA, Broeckel U, Grim CE, Hamet P, Jacob H, Kaldunski ML, Kotchen JM, Schork NJ, Tonellato PJ, Cowley AW Jr) Hypertension 2002 Nov;40(5):634-9 PMID: 12411455 11/02/2002
  • A comprehensive linkage analysis for myocardial infarction and its related risk factors. (Broeckel U, Hengstenberg C, Mayer B, Holmer S, Martin LJ, Comuzzie AG, Blangero J, Nürnberg P, Reis A, Riegger GA, Jacob HJ, Schunkert H) Nat Genet 2002 Feb;30(2):210-4 PMID: 11818963 01/31/2002
  • The future of genetic case-control studies. (Schork NJ, Fallin D, Thiel B, Xu X, Broeckel U, Jacob HJ, Cohen D) Adv Genet 2001;42:191-212 PMID: 11037322 10/19/2000
  • Localization of a small genomic region associated with elevated ACE. (Zhu X, McKenzie CA, Forrester T, Nickerson DA, Broeckel U, Schunkert H, Doering A, Jacob HJ, Cooper RS, Rieder MJ) Am J Hum Genet 2000 Nov;67(5):1144-53 PMID: 11001581 PMCID: PMC1288557 09/23/2000
  • Lack of association between a polymorphism of the aldosterone synthase gene and left ventricular structure. (Schunkert H, Hengstenberg C, Holmer SR, Broeckel U, Luchner A, Muscholl MW, Kürzinger S, Döring A, Hense HW, Riegger GA) Circulation 1999 May 04;99(17):2255-60 PMID: 10226090 05/05/1999
  • The associations of body size and body composition with left ventricular mass: impacts for indexation in adults. (Hense HW, Gneiting B, Muscholl M, Broeckel U, Kuch B, Doering A, Riegger GA, Schunkert H) J Am Coll Cardiol 1998 Aug;32(2):451-7 PMID: 9708475 08/26/1998
  • Left-ventricular dysfunction. (Schunkert H, Broeckel U, Hense HW, Keil U, Riegger GA) Lancet 1998 Jan 31;351(9099):372 PMID: 9652648 07/04/1998
  • Susceptibility genes for end-organ damage. New strategies to understand diabetic and hypertensive nephropathy. (Broeckel U, Shiozawa M, Kissebah AH, Provoost AP, Jacob HJ) Nephrol Dial Transplant 1998 Apr;13(4):840-2 PMID: 9568834 05/06/1998
  • Last update: 05/31/2013
    jenkins-FCD Prod-130 96200611f8481f0aa4f84230b11dd74d063847a3