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Publications indexed to the term Gene Deletion

FacultyTitle
1Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. (Sun X, Wu B, Chiang HC, Deng H, Zhang X, Xiong W, Liu J, Rozeboom AM, Harris BT, Blommaert E, Gomez A, Garcia RE, Zhou Y, Mitra P, Prevost M, Zhang D, Banik D, Isaacs C, Berry D, Lai C, Chaldekas K, Latham PS, Brantner CA, Popratiloff A, Jin VX, Zhang N, Hu Y, Pujana MA, Curiel TJ, An Z, Li R) Nature 2021 Nov;599(7886):673-678       129 Citations
1BBSome ablation in SF1 neurons causes obesity without comorbidities. (Rouabhi M, Guo DF, Morgan DA, Zhu Z, López M, Zingman L, Grobe JL, Rahmouni K) Mol Metab 2021 Jun;48:101211       14 Citations
1mTORC1 (Mechanistic Target of Rapamycin Complex 1) Signaling in Endothelial and Smooth Muscle Cells Is Required for Vascular Function. (Reho JJ, Guo DF, Morgan DA, Rahmouni K) Hypertension 2021 Feb;77(2):594-604       12 Citations
1Pathogenic paternally inherited NLGN4X deletion in a female with autism spectrum disorder: Clinical, cytogenetic, and molecular characterization. (Kopp N, Amarillo I, Martinez-Agosto J, Quintero-Rivera F) Am J Med Genet A 2021 Mar;185(3):894-900       5 Citations
2Arid2 regulates hematopoietic stem cell differentiation in normal hematopoiesis. (Bluemn T, Schmitz J, Chen Y, Zheng Y, Zhang Y, Zheng S, Burns R, DeJong J, Christiansen L, Izaguirre-Carbonell J, Wang D, Zhu N) Exp Hematol 2021 Feb;94:37-46       8 Citations
2Café au lait spots: When and how to pursue their genetic origins. (Lalor L, Davies OMT, Basel D, Siegel DH) Clin Dermatol 2020;38(4):421-431       16 Citations
1Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes. (Lee H, Lee YS, Harenda Q, Pietrzak S, Oktay HZ, Schreiber S, Liao Y, Sonthalia S, Ciecko AE, Chen YG, Keles S, Sridharan R, Engin F) Cell Metab 2020 Apr 07;31(4):822-836.e5       73 Citations
1Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury. (Yurdagul A Jr, Subramanian M, Wang X, Crown SB, Ilkayeva OR, Darville L, Kolluru GK, Rymond CC, Gerlach BD, Zheng Z, Kuriakose G, Kevil CG, Koomen JM, Cleveland JL, Muoio DM, Tabas I) Cell Metab 2020 Mar 03;31(3):518-533.e10       210 Citations
1Mitochondrial DNA Depletion Syndromes. (Basel D) Clin Perinatol 2020 Mar;47(1):123-141       17 Citations
1Disease burden of Crigler-Najjar syndrome: Systematic review and future perspectives. (Dhawan A, Lawlor MW, Mazariegos GV, McKiernan P, Squires JE, Strauss KA, Gupta D, James E, Prasad S) J Gastroenterol Hepatol 2020 Apr;35(4):530-543       21 Citations
1FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis. (Seshacharyulu P, Rachagani S, Muniyan S, Siddiqui JA, Cruz E, Sharma S, Krishnan R, Killips BJ, Sheinin Y, Lele SM, Smith LM, Talmon GA, Ponnusamy MP, Datta K, Batra SK) Oncogene 2019 Jun;38(26):5265-5280       38 Citations
1Protein modeling and clinical description of a novel in-frame GLB1 deletion causing GM1 gangliosidosis type II. (Richter JE Jr, Zimmermann MT, Blackburn PR, Mohammad AN, Klee EW, Pollard LM, Macmurdo CF, Atwal PS, Caulfield TR) Mol Genet Genomic Med 2018 Nov;6(6):1229-1235       5 Citations
1Endoreduplication of the mouse genome in the absence of ORC1. (Okano-Uchida T, Kent LN, Ouseph MM, McCarty B, Frank JJ, Kladney R, Cuitino MC, Thompson JC, Coppola V, Asano M, Leone G) Genes Dev 2018 Jul 01;32(13-14):978-990       15 Citations
1Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly. (Wotton D, Taniguchi K) Am J Med Genet C Semin Med Genet 2018 Jun;178(2):128-139       12 Citations
1Targeted knockout of a chemokine-like gene increases anxiety and fear responses. (Choi JH, Jeong YM, Kim S, Lee B, Ariyasiri K, Kim HT, Jung SH, Hwang KS, Choi TI, Park CO, Huh WK, Carl M, Rosenfeld JA, Raskin S, Ma A, Gecz J, Kim HG, Kim JS, Shin HC, Park DS, Gerlai R, Jamieson BB, Kim JS, Iremonger KJ, Lee SH, Shin HS, Kim CH) Proc Natl Acad Sci U S A 2018 Jan 30;115(5):E1041-E1050       36 Citations
1Characterization of Stress and Innate Immunity Resistance of Wild-Type and Δp66 Borrelia burgdorferi. (Curtis MW, Hahn BL, Zhang K, Li C, Robinson RT, Coburn J) Infect Immun 2018 Feb;86(2)       10 Citations
1Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma. (Protas ME, Weh E, Footz T, Kasberger J, Baraban SC, Levin AV, Katz LJ, Ritch R, Walter MA, Semina EV, Gould DB) Hum Mol Genet 2017 Sep 15;26(18):3630-3638       26 Citations
1RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia. (Choi A, Illendula A, Pulikkan JA, Roderick JE, Tesell J, Yu J, Hermance N, Zhu LJ, Castilla LH, Bushweller JH, Kelliher MA) Blood 2017 Oct 12;130(15):1722-1733       53 Citations
1Clinicopathologic and molecular markers in cervical carcinoma: a prospective cohort study. (Halle MK, Ojesina AI, Engerud H, Woie K, Tangen IL, Holst F, Høivik E, Kusonmano K, Haldorsen IS, Vintermyr OK, Trovik J, Bertelsen BI, Salvesen HB, Krakstad C) Am J Obstet Gynecol 2017 Oct;217(4):432.e1-432.e17       37 Citations
3Requirement of the CroRS Two-Component System for Resistance to Cell Wall-Targeting Antimicrobials in Enterococcus faecium. (Kellogg SL, Little JL, Hoff JS, Kristich CJ) Antimicrob Agents Chemother 2017 May;61(5)       35 Citations
1Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. (Yan X, Himburg HA, Pohl K, Quarmyne M, Tran E, Zhang Y, Fang T, Kan J, Chao NJ, Zhao L, Doan PL, Chute JP) Cell Rep 2016 Nov 01;17(6):1584-1594       20 Citations
1E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. (Swartz KL, Wood SN, Murthy T, Ramirez O, Qin G, Pillai MM, Rao S, Minella AC) Mol Cell Biol 2017 Jan 01;37(1)       21 Citations
2Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension. (Shinohara K, Liu X, Morgan DA, Davis DR, Sequeira-Lopez ML, Cassell MD, Grobe JL, Rahmouni K, Sigmund CD) Hypertension 2016 Dec;68(6):1385-1392       42 Citations
1Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. (Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, Rosol TJ, Shakya R, Ludwig T, Lesinski GB, Fernandez SA, Konieczny SF, Leone G, Wu J, Ostrowski MC) Neoplasia 2016 Sep;18(9):541-52       25 Citations
1Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. (Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC) Genes Dev 2016 Sep 01;30(17):1943-55       46 Citations
2The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9. (Fisher JB, Peterson J, Reimer M, Stelloh C, Pulakanti K, Gerbec ZJ, Abel AM, Strouse JM, Strouse C, McNulty M, Malarkannan S, Crispino JD, Milanovich S, Rao S) Leukemia 2017 Mar;31(3):712-719       41 Citations
2E2f8 mediates tumor suppression in postnatal liver development. (Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G) J Clin Invest 2016 Aug 01;126(8):2955-69       66 Citations
1Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. (Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T) Nature 2016 Jun 16;534(7607):407-411       108 Citations
1A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. (Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck MD, Meza J, Sheinin Y, Band V, Band H) Oncotarget 2016 Aug 09;7(32):51107-51123       8 Citations
2Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. (Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M) J Am Heart Assoc 2016 Feb 17;5(2)       42 Citations
3Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes. (Mathison A, Escande C, Calvo E, Seo S, White T, Salmonson A, Faubion WA Jr, Buttar N, Iovanna J, Lomberk G, Chini EN, Urrutia R) Endocrinology 2015 Oct;156(10):3581-95       9 Citations
1Dietary Sodium Suppresses Digestive Efficiency via the Renin-Angiotensin System. (Weidemann BJ, Voong S, Morales-Santiago FI, Kahn MZ, Ni J, Littlejohn NK, Claflin KE, Burnett CM, Pearson NA, Lutter ML, Grobe JL) Sci Rep 2015 Jun 11;5:11123       25 Citations
1Genetic Confirmation that the H5 Protein Is Required for Vaccinia Virus DNA Replication. (Boyle KA, Greseth MD, Traktman P) J Virol 2015 Jun;89(12):6312-27       16 Citations
2Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. (Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H) Blood 2015 Feb 05;125(6):1014-24       42 Citations
1Cited2 is required in trophoblasts for correct placental capillary patterning. (Moreau JL, Artap ST, Shi H, Chapman G, Leone G, Sparrow DB, Dunwoodie SL) Dev Biol 2014 Aug 01;392(1):62-79       34 Citations
1TPL2 kinase regulates the inflammatory milieu of the myeloma niche. (Hope C, Ollar SJ, Heninger E, Hebron E, Jensen JL, Kim J, Maroulakou I, Miyamoto S, Leith C, Yang DT, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F) Blood 2014 May 22;123(21):3305-15       79 Citations
1Varied manifestations of persistent hyperplastic primary vitreous with graded somatic mosaic deletion of a single gene. (Mary-Sinclair MN, Wang X, Swanson DJ, Sung CY, Mendonca EA, Wroblewski K, Baumer SH, Goldowitz D, Jablonski MM, Skapek SX) Mol Vis 2014;20:215-30       3 Citations
1Aberrant bone density in aging mice lacking the adenosine transporter ENT1. (Hinton DJ, McGee-Lawrence ME, Lee MR, Kwong HK, Westendorf JJ, Choi DS) PLoS One 2014;9(2):e88818       22 Citations
1A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect. (Sun Y, Myers CJ, Dicker AP, Lu B) PLoS One 2014;9(2):e87492       3 Citations
1Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. (Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G) Oncogene 2015 Jan 02;34(1):119-28       27 Citations
1Human cone visual pigment deletions spare sufficient photoreceptors to warrant gene therapy. (Cideciyan AV, Hufnagel RB, Carroll J, Sumaroka A, Luo X, Schwartz SB, Dubra A, Land M, Michaelides M, Gardner JC, Hardcastle AJ, Moore AT, Sisk RA, Ahmed ZM, Kohl S, Wissinger B, Jacobson SG) Hum Gene Ther 2013 Dec;24(12):993-1006       91 Citations
1Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. (Wallace JA, Li F, Balakrishnan S, Cantemir-Stone CZ, Pecot T, Martin C, Kladney RD, Sharma SM, Trimboli AJ, Fernandez SA, Yu L, Rosol TJ, Stromberg PC, Lesurf R, Hallett M, Park M, Leone G, Ostrowski MC) PLoS One 2013;8(8):e71533       32 Citations
1Thrombospondin-1 modulates VEGF signaling via CD36 by recruiting SHP-1 to VEGFR2 complex in microvascular endothelial cells. (Chu LY, Ramakrishnan DP, Silverstein RL) Blood 2013 Sep 05;122(10):1822-32       111 Citations
1Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy. (Ottenheijm CA, Buck D, de Winter JM, Ferrara C, Piroddi N, Tesi C, Jasper JR, Malik FI, Meng H, Stienen GJ, Beggs AH, Labeit S, Poggesi C, Lawlor MW, Granzier H) Brain 2013 Jun;136(Pt 6):1718-31       51 Citations
1Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling. (Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Borok Z, Li C, Minoo P) PLoS One 2013;8(4):e62215       17 Citations
1Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis. (Ey B, Eyking A, Klepak M, Salzman NH, Göthert JR, Rünzi M, Schmid KW, Gerken G, Podolsky DK, Cario E) J Immunol 2013 Jun 01;190(11):5676-88       48 Citations
1Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding. (Bigley TM, Reitsma JM, Mirza SP, Terhune SS) J Virol 2013 Jul;87(13):7393-408       28 Citations
1The Listeria monocytogenes ChiA chitinase enhances virulence through suppression of host innate immunity. (Chaudhuri S, Gantner BN, Ye RD, Cianciotto NP, Freitag NE) mBio 2013 Mar 19;4(2):e00617-12       43 Citations
1TRPV1, but not TRPA1, in primary sensory neurons contributes to cutaneous incision-mediated hypersensitivity. (Barabas ME, Stucky CL) Mol Pain 2013 Mar 04;9:9       46 Citations
1Dps promotes survival of nontypeable Haemophilus influenzae in biofilm communities in vitro and resistance to clearance in vivo. (Pang B, Hong W, Kock ND, Swords WE) Front Cell Infect Microbiol 2012;2:58       23 Citations
1E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. (Weijts BG, Bakker WJ, Cornelissen PW, Liang KH, Schaftenaar FH, Westendorp B, de Wolf CA, Paciejewska M, Scheele CL, Kent L, Leone G, Schulte-Merker S, de Bruin A) EMBO J 2012 Oct 03;31(19):3871-84       99 Citations
1The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence. (Youm YH, Kanneganti TD, Vandanmagsar B, Zhu X, Ravussin A, Adijiang A, Owen JS, Thomas MJ, Francis J, Parks JS, Dixit VD) Cell Rep 2012 Jan 26;1(1):56-68       115 Citations
2The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks. (Ristow LC, Miller HE, Padmore LJ, Chettri R, Salzman N, Caimano MJ, Rosa PA, Coburn J) Mol Microbiol 2012 Sep;85(6):1105-18       48 Citations
1MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c. (Bretl DJ, He H, Demetriadou C, White MJ, Penoske RM, Salzman NH, Zahrt TC) Infect Immun 2012 Sep;80(9):3018-33       36 Citations
1Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition. (Kerns SL, Schultz KM, Barry KA, Thorne TM, McGarry TJ) PLoS One 2012;7(5):e38009       14 Citations
2A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. (Hilzendeger AM, Morgan DA, Brooks L, Dellsperger D, Liu X, Grobe JL, Rahmouni K, Sigmund CD, Mark AL) Am J Physiol Heart Circ Physiol 2012 Jul 15;303(2):H197-206       98 Citations
3PITX2 and FOXC1 spectrum of mutations in ocular syndromes. (Reis LM, Tyler RC, Volkmann Kloss BA, Schilter KF, Levin AV, Lowry RB, Zwijnenburg PJ, Stroh E, Broeckel U, Murray JC, Semina EV) Eur J Hum Genet 2012 Dec;20(12):1224-33       113 Citations
2Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. (Hamidi T, Algül H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, Urrutia R, Schmid RM, Iovanna JL) J Clin Invest 2012 Jun;122(6):2092-103       101 Citations
2E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 protein during restitution. (Hwang S, Zimmerman NP, Agle KA, Turner JR, Kumar SN, Dwinell MB) J Biol Chem 2012 Jun 22;287(26):22227-40       36 Citations
1Cytokine-mediated β-cell damage in PARP-1-deficient islets. (Andreone T, Meares GP, Hughes KJ, Hansen PA, Corbett JA) Am J Physiol Endocrinol Metab 2012 Jul 15;303(2):E172-9       19 Citations
1Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell mass. (Kimple ME, Moss JB, Brar HK, Rosa TC, Truchan NA, Pasker RL, Newgard CB, Casey PJ) J Biol Chem 2012 Jun 08;287(24):20344-55       30 Citations
2MurAA is required for intrinsic cephalosporin resistance of Enterococcus faecalis. (Vesić D, Kristich CJ) Antimicrob Agents Chemother 2012 May;56(5):2443-51       35 Citations
1Thrombomodulin is required for the antithrombotic activity of thrombin mutant W215A/E217A in a mouse model of arterial thrombosis. (Vicente CP, Weiler H, Di Cera E, Tollefsen DM) Thromb Res 2012 Oct;130(4):646-8       10 Citations
1Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. (Zhong P, Pan B, Gao XP, Blankman JL, Cravatt BF, Liu QS) J Physiol 2011 Oct 15;589(Pt 20):4847-55       55 Citations
1Role of Mrx fimbriae of Xenorhabdus nematophila in competitive colonization of the nematode host. (Snyder H, He H, Owen H, Hanna C, Forst S) Appl Environ Microbiol 2011 Oct;77(20):7247-54       2 Citations
1Genetics of anterior segment dysgenesis disorders. (Reis LM, Semina EV) Curr Opin Ophthalmol 2011 Sep;22(5):314-24       113 Citations
2Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃. (Lakshmikanthan S, Sobczak M, Chun C, Henschel A, Dargatz J, Ramchandran R, Chrzanowska-Wodnicka M) Blood 2011 Aug 18;118(7):2015-26       92 Citations
1The Borrelia burgdorferi integrin ligand P66 affects gene expression by human cells in culture. (LaFrance ME, Pierce JV, Antonara S, Coburn J) Infect Immun 2011 Aug;79(8):3249-61       16 Citations
1Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development. (Kur E, Christa A, Veth KN, Gajera CR, Andrade-Navarro MA, Zhang J, Willer JR, Gregg RG, Abdelilah-Seyfried S, Bachmann S, Link BA, Hammes A, Willnow TE) Dev Dyn 2011 Jun;240(6):1567-77       35 Citations
1Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. (Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, Mark AL, Rahmouni K) Circ Res 2011 Apr 01;108(7):808-12       120 Citations
5Potential novel mechanism for Axenfeld-Rieger syndrome: deletion of a distant region containing regulatory elements of PITX2. (Volkmann BA, Zinkevich NS, Mustonen A, Schilter KF, Bosenko DV, Reis LM, Broeckel U, Link BA, Semina EV) Invest Ophthalmol Vis Sci 2011 Mar;52(3):1450-9       41 Citations
1Color-deficient cone mosaics associated with Xq28 opsin mutations: a stop codon versus gene deletions. (Wagner-Schuman M, Neitz J, Rha J, Williams DR, Neitz M, Carroll J) Vision Res 2010 Nov 23;50(23):2396-402       24 Citations
1Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol. (Zhu X, Owen JS, Wilson MD, Li H, Griffiths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS) J Lipid Res 2010 Nov;51(11):3196-206       268 Citations
1Deletion of the X-linked opsin gene array locus control region (LCR) results in disruption of the cone mosaic. (Carroll J, Rossi EA, Porter J, Neitz J, Roorda A, Williams DR, Neitz M) Vision Res 2010 Sep 15;50(19):1989-99       45 Citations
1Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. (Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A) Development 2010 Aug;137(16):2643-52       122 Citations
1Loss of individual microRNAs causes mutant phenotypes in sensitized genetic backgrounds in C. elegans. (Brenner JL, Jasiewicz KL, Fahley AF, Kemp BJ, Abbott AL) Curr Biol 2010 Jul 27;20(14):1321-5       105 Citations
1In vivo studies of mutant fibrillin-1 microfibrils. (Charbonneau NL, Carlson EJ, Tufa S, Sengle G, Manalo EC, Carlberg VM, Ramirez F, Keene DR, Sakai LY) J Biol Chem 2010 Aug 06;285(32):24943-55       75 Citations
4Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70       68 Citations
2OTX2 microphthalmia syndrome: four novel mutations and delineation of a phenotype. (Schilter KF, Schneider A, Bardakjian T, Soucy JF, Tyler RC, Reis LM, Semina EV) Clin Genet 2011 Feb;79(2):158-68       83 Citations
1Examination of SOX2 in variable ocular conditions identifies a recurrent deletion in microphthalmia and lack of mutations in other phenotypes. (Reis LM, Tyler RC, Schneider A, Bardakjian T, Semina EV) Mol Vis 2010 Apr 28;16:768-73       20 Citations
1Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. (Srinivasan R, Zabuawala T, Huang H, Zhang J, Gulati P, Fernandez S, Karlo JC, Landreth GE, Leone G, Ostrowski MC) PLoS One 2009 Dec 14;4(12):e8283       135 Citations
2Pten in stromal fibroblasts suppresses mammary epithelial tumours. (Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G) Nature 2009 Oct 22;461(7267):1084-91       441 Citations
1Isolated facial diplegia and very late-onset myopathy in two siblings: atypical presentations of facioscapulohumeral dystrophy. (Figueroa JJ, Chapin JE) J Neurol 2010 Mar;257(3):444-6       7 Citations
1Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells. (Maekawa Y, Mizue N, Chan A, Shi Y, Liu Y, Dawood S, Chen M, Dawood F, de Couto G, Li GH, Suzuki N, Yeh WC, Gramolini A, Medin JA, Liu PP) Circulation 2009 Oct 06;120(14):1401-14       66 Citations
1Genetic analysis of xenocoumacin antibiotic production in the mutualistic bacterium Xenorhabdus nematophila. (Park D, Ciezki K, van der Hoeven R, Singh S, Reimer D, Bode HB, Forst S) Mol Microbiol 2009 Sep;73(5):938-49       69 Citations
4An autoinflammatory disease due to homozygous deletion of the IL1RN locus. (Reddy S, Jia S, Geoffrey R, Lorier R, Suchi M, Broeckel U, Hessner MJ, Verbsky J) N Engl J Med 2009 Jun 04;360(23):2438-44       341 Citations
1OpnS, an outer membrane porin of Xenorhabdus nematophila, confers a competitive advantage for growth in the insect host. (van der Hoeven R, Forst S) J Bacteriol 2009 Sep;191(17):5471-9       8 Citations
1Functional genomics of Enterococcus faecalis: multiple novel genetic determinants for biofilm formation in the core genome. (Ballering KS, Kristich CJ, Grindle SM, Oromendia A, Beattie DT, Dunny GM) J Bacteriol 2009 Apr;191(8):2806-14       51 Citations
1Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach. (Xu J, Song P, Miller ML, Borgese F, Barone S, Riederer B, Wang Z, Alper SL, Forte JG, Shull GE, Ehrenfeld J, Seidler U, Soleimani M) Proc Natl Acad Sci U S A 2008 Nov 18;105(46):17955-60       92 Citations
1Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development. (Hu Z, Liu Y, Zhang C, Zhao Y, He W, Han L, Yang L, Hopkins KM, Yang X, Lieberman HB, Hang H) Cancer Res 2008 Jul 15;68(14):5552-61       30 Citations
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