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Publications indexed to the term T-Lymphocytes, Regulatory

FacultyTitle
3BATF is Required for Treg Homeostasis and Stability to Prevent Autoimmune Pathology. (Khatun A, Wu X, Qi F, Gai K, Kharel A, Kudek MR, Fraser L, Ceicko A, Kasmani MY, Majnik A, Burns R, Chen YG, Salzman N, Taparowsky EJ, Fang D, Williams CB, Cui W) Adv Sci (Weinh) 2023 Oct;10(28):e2206692       2 Citations
1Exosomes, MDSCs and Tregs: A new frontier for GVHD prevention and treatment. (Hess NJ, Kink JA, Hematti P) Front Immunol 2023;14:1143381       2 Citations
1G9a Modulates Lipid Metabolism in CD4 T Cells to Regulate Intestinal Inflammation. (Ramos GP, Bamidele AO, Klatt EE, Sagstetter MR, Kurdi AT, Hamdan FH, Kosinsky RL, Gaballa JM, Nair A, Sun Z, Dasari S, Lanza IR, Rozeveld CN, Schott MB, Urrutia G, Westphal MS, Clarkson BD, Howe CL, Marietta EV, Luckey DH, Murray JA, Gonzalez M, Braga Neto MB, Gibbons HR, Smyrk TC, Johnsen S, Lomberk G, Faubion WA) Gastroenterology 2023 Feb;164(2):256-271.e10       9 Citations
1The long and winding road: From mouse linkage studies to a novel human therapeutic pathway in type 1 diabetes. (Rojas M, Heuer LS, Zhang W, Chen YG, Ridgway WM) Front Immunol 2022;13:918837       1 Citation
2BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease. (Gonzalez MM, Bamidele AO, Svingen PA, Sagstetter MR, Smyrk TC, Gaballa JM, Hamdan FH, Kosinsky RL, Gibbons HR, Sun Z, Ye Z, Nair A, Ramos GP, Braga Neto MB, Wixom AQ, Mathison AJ, Johnsen SA, Urrutia R, Faubion WA Jr) J Clin Invest 2021 Jun 15;131(12)       13 Citations
1Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice. (Allred MG, Chimenti MS, Ciecko AE, Chen YG, Lieberman SM) Int J Mol Sci 2021 Apr 05;22(7)       7 Citations
1Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease. (Nguyen HD, Ticer T, Bastian D, Kuril S, Li H, Du H, Yan C, Yu XZ) Cell Rep 2020 Oct 27;33(4):108316       5 Citations
2Mutation of RORγT reveals a role for Th17 cells in both injury and recovery from renal ischemia-reperfusion injury. (Mehrotra P, Ullah MM, Collett JA, Myers SL, Dwinell MR, Geurts AM, Basile DP) Am J Physiol Renal Physiol 2020 Nov 01;319(5):F796-F808       14 Citations
1Encapsulated Checkpoint Blocker Before Chemotherapy: The Optimal Sequence of Anti-CTLA-4 and Doxil Combination Therapy. (Alimohammadi R, Alibeigi R, Nikpoor AR, Chalbatani GM, Webster TJ, Jaafari MR, Jalali SA) Int J Nanomedicine 2020;15:5279-5288       19 Citations
1Regulatory T Cells Contribute to Resistance against Lyme Arthritis. (Siebers EM, Liedhegner ES, Lawlor MW, Schell RF, Nardelli DT) Infect Immun 2020 Oct 19;88(11)       6 Citations
1RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity. (Ansa-Addo EA, Huang HC, Riesenberg B, Iamsawat S, Borucki D, Nelson MH, Nam JH, Chung D, Paulos CM, Liu B, Yu XZ, Philpott C, Howe PH, Li Z) Sci Adv 2020 May;6(22):eaaz3865       29 Citations
1The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137+ FOXP3+ Regulatory CD4 T Cells. (Foda BM, Ciecko AE, Serreze DV, Ridgway WM, Geurts AM, Chen YG) J Immunol 2020 Jun 01;204(11):2887-2899       8 Citations
1Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. (Chan AY, Leiding JW, Liu X, Logan BR, Burroughs LM, Allenspach EJ, Skoda-Smith S, Uzel G, Notarangelo LD, Slatter M, Gennery AR, Smith AR, Pai SY, Jordan MB, Marsh RA, Cowan MJ, Dvorak CC, Craddock JA, Prockop SE, Chandrakasan S, Kapoor N, Buckley RH, Parikh S, Chellapandian D, Oshrine BR, Bednarski JJ, Cooper MA, Shenoy S, Davila Saldana BJ, Forbes LR, Martinez C, Haddad E, Shyr DC, Chen K, Sullivan KE, Heimall J, Wright N, Bhatia M, Cuvelier GDE, Goldman FD, Meyts I, Miller HK, Seidel MG, Vander Lugt MT, Bacchetta R, Weinacht KG, Andolina JR, Caywood E, Chong H, de la Morena MT, Aquino VM, Shereck E, Walter JE, Dorsey MJ, Seroogy CM, Griffith LM, Kohn DB, Puck JM, Pulsipher MA, Torgerson TR) Front Immunol 2020;11:239       56 Citations
1Vitamin C stabilizes CD8+ iTregs and enhances their therapeutic potential in controlling murine GVHD and leukemia relapse. (Iamsawat S, Tian L, Daenthanasanmak A, Wu Y, Nguyen HD, Bastian D, Yu XZ) Blood Adv 2019 Dec 23;3(24):4187-4201       17 Citations
2Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation. (Ciecko AE, Foda B, Barr JY, Ramanathan S, Atkinson MA, Serreze DV, Geurts AM, Lieberman SM, Chen YG) Cell Rep 2019 Dec 03;29(10):3073-3086.e5       34 Citations
1Regulatory T Cells Control PF4/Heparin Antibody Production in Mice. (Zheng Y, Zhu W, Haribhai D, Williams CB, Aster RH, Wen R, Wang D) J Immunol 2019 Oct 01;203(7):1786-1792       11 Citations
1CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade. (Garcia-Perez JE, Baxter RM, Kong DS, Tobin R, McCarter M, Routes JM, Verbsky J, Jordan MB, Dutmer CM, Hsieh EWY) Front Immunol 2019;10:998       11 Citations
1Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus. (Forsberg MH, Foda B, Serreze DV, Chen YG) Sci Rep 2019 Mar 13;9(1):4316       7 Citations
2Thymic regulatory T cells arise via two distinct developmental programs. (Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA) Nat Immunol 2019 Feb;20(2):195-205       152 Citations
2Mature IgDlow/- B cells maintain tolerance by promoting regulatory T cell homeostasis. (Ray A, Khalil MI, Pulakanti KL, Burns RT, Gurski CJ, Basu S, Wang D, Rao S, Dittel BN) Nat Commun 2019 Jan 14;10(1):190       24 Citations
1Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. (Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ) JCI Insight 2018 Dec 20;3(24)       24 Citations
1Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice. (Daenthanasanmak A, Iamsawat S, Chakraborty P, Nguyen HD, Bastian D, Liu C, Mehrotra S, Yu XZ) Blood 2019 Jan 17;133(3):266-279       61 Citations
2Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. (Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA Jr) Cell Mol Gastroenterol Hepatol 2019;7(1):55-71       24 Citations
1Stabilization of Foxp3 by Targeting JAK2 Enhances Efficacy of CD8 Induced Regulatory T Cells in the Prevention of Graft-versus-Host Disease. (Iamsawat S, Daenthanasanmak A, Voss JH, Nguyen H, Bastian D, Liu C, Yu XZ) J Immunol 2018 Nov 01;201(9):2812-2823       27 Citations
4Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells. (Luo X, Chen J, Schroeder JA, Allen KP, Baumgartner CK, Malarkannan S, Hu J, Williams CB, Shi Q) Front Immunol 2018;9:1950       12 Citations
1Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma. (Retseck J, Nasr A, Lin Y, Lin H, Mendiratta P, Butterfield LH, Tarhini AA) J Transl Med 2018 Jul 04;16(1):184       39 Citations
1Telomerase: Location, Location, Location? (Beyer AM, Norwood Toro LE) Arterioscler Thromb Vasc Biol 2018 Jun;38(6):1247-1249       2 Citations
1Bim regulates the survival and suppressive capability of CD8+ FOXP3+ regulatory T cells during murine GVHD. (Agle K, Vincent BG, Piper C, Belle L, Zhou V, Shlomchik W, Serody JS, Drobyski WR) Blood 2018 Jul 26;132(4):435-447       31 Citations
1Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis. (Gaddis DE, Padgett LE, Wu R, McSkimming C, Romines V, Taylor AM, McNamara CA, Kronenberg M, Crotty S, Thomas MJ, Sorci-Thomas MG, Hedrick CC) Nat Commun 2018 Mar 15;9(1):1095       122 Citations
3CD30 Expression in Monomorphic Posttransplant Lymphoproliferative Disorder, Diffuse Large B-Cell Lymphoma Correlates With Greater Regulatory T-Cell Infiltration. (Hartley C, Vaughan JW, Jarzembowski J, Kroft SH, Hosking P, Harrington AM, Olteanu H) Am J Clin Pathol 2017 Nov 20;148(6):485-493       11 Citations
1Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated. (Chen Y, Luo X, Schroeder JA, Chen J, Baumgartner CK, Hu J, Shi Q) J Thromb Haemost 2017 Oct;15(10):1994-2004       25 Citations
1Anti-inflammatory liaisons: T regulatory cells and HDL. (Sorci-Thomas MG, Thomas MJ) J Lipid Res 2017 Aug;58(8):1491-1492       3 Citations
1CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. (Forsberg MH, Ciecko AE, Bednar KJ, Itoh A, Kachapati K, Ridgway WM, Chen YG) J Immunol 2017 May 15;198(10):3857-3868       17 Citations
1Novel pathogenic variants in FOXP3 in fetuses with echogenic bowel and skin desquamation identified by ultrasound. (Louie RJ, Tan QK, Gilner JB, Rogers RC, Younge N, Wechsler SB, McDonald MT, Gordon B, Saski CA, Jones JR, Chapman SJ, Stevenson RE, Sleasman JW, Friez MJ) Am J Med Genet A 2017 May;173(5):1219-1225       31 Citations
1CD25 Blockade Delays Regulatory T Cell Reconstitution and Does Not Prevent Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation. (Locke FL, Pidala J, Storer B, Martin PJ, Pulsipher MA, Chauncey TR, Jacobsen N, Kröger N, Walker I, Light S, Shaw BE, Beato F, Laport GG, Nademanee A, Keating A, Socie G, Anasetti C) Biol Blood Marrow Transplant 2017 Mar;23(3):405-411       12 Citations
1Interferon-γ Limits Diabetogenic CD8+ T-Cell Effector Responses in Type 1 Diabetes. (Driver JP, Racine JJ, Ye C, Lamont DJ, Newby BN, Leeth CM, Chapman HD, Brusko TM, Chen YG, Mathews CE, Serreze DV) Diabetes 2017 Mar;66(3):710-721       25 Citations
2The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). (Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, Xavier RJ, Urrutia RA, Faubion WA) J Biol Chem 2017 Jan 13;292(2):706-722       54 Citations
1Cardiac-deleterious role of galectin-3 in chronic angiotensin II-induced hypertension. (González GE, Rhaleb NE, D'Ambrosio MA, Nakagawa P, Liao TD, Peterson EL, Leung P, Dai X, Janic B, Liu YH, Yang XP, Carretero OA) Am J Physiol Heart Circ Physiol 2016 Nov 01;311(5):H1287-H1296       57 Citations
1Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice. (Lin B, Ciecko AE, MacKinney E, Serreze DV, Chen YG) Immunogenetics 2017 Mar;69(3):193-198       2 Citations
2Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression. (Belle L, Agle K, Zhou V, Yin-Yuan C, Komorowski R, Eastwood D, Logan B, Sun J, Ghilardi N, Cua D, Williams CB, Gaignage M, Marillier R, van Snick J, Drobyski WR) Blood 2016 Oct 20;128(16):2068-2082       34 Citations
1Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. (Cheng HY, Gaddis DE, Wu R, McSkimming C, Haynes LD, Taylor AM, McNamara CA, Sorci-Thomas M, Hedrick CC) J Clin Invest 2016 Sep 01;126(9):3236-46       59 Citations
1Editorial: Treg potency and the importance of being fit. (Jeschke JC, Williams CB) J Leukoc Biol 2016 Jul;100(1):1-3       1 Citation
1Immunotherapy with iTreg and nTreg Cells in a Murine Model of Inflammatory Bowel Disease. (Haribhai D, Chatila TA, Williams CB) Methods Mol Biol 2016;1422:197-211       22 Citations
1Advances in understanding the pathogenesis of graft-versus-host disease. (Magenau J, Runaas L, Reddy P) Br J Haematol 2016 Apr;173(2):190-205       67 Citations
5Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis. (Haribhai D, Ziegelbauer J, Jia S, Upchurch K, Yan K, Schmitt EG, Salzman NH, Simpson P, Hessner MJ, Chatila TA, Williams CB) J Immunol 2016 Apr 15;196(8):3305-17       37 Citations
1Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic. (Majchrzak K, Nelson MH, Bailey SR, Bowers JS, Yu XZ, Rubinstein MP, Himes RA, Paulos CM) Cancer Immunol Immunother 2016 Mar;65(3):247-59       33 Citations
3Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency. (Gurram B, Hammelev E, Syverson G, Haribhai D, Yan K, Simpson P, Salzman N, Verbsky JW) J Pediatr Gastroenterol Nutr 2016 Aug;63(2):218-25    
1Proceedings from the Second Haploidentical Stem Cell Transplantation Symposium-Haplo2014, San Francisco, California, December 4, 2014. (Al Malki MM, Horowitz M, Handgretinger R, Leung W, Roy DC, Huang XJ, Fuchs E, Locatelli F, Blaise D, Mineishi S, Martelli M, Miller J, June C, Ai HS, Luznik L, Mavilio D, Lugli E, van den Brink MRM, Champlin RE, Ciurea SO) Biol Blood Marrow Transplant 2016 Apr;22(4):594-604       9 Citations
1The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. (Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV) J Immunol 2015 Oct 01;195(7):3011-9       11 Citations
1MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3. (Zhang L, Ke F, Liu Z, Bai J, Liu J, Yan S, Xu Z, Lou F, Wang H, Zhu H, Sun Y, Cai W, Gao Y, Li Q, Yu XZ, Qian Y, Hua Z, Deng J, Li QJ, Wang H) Nat Commun 2015 Jul 13;6:7639       78 Citations
1HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host Disease. (Li J, Heinrichs J, Haarberg K, Semple K, Veerapathran A, Liu C, Anasetti C, Yu XZ) J Immunol 2015 Jul 15;195(2):717-25       22 Citations
1Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. (Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson ED, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, Varghese N, McClain KL, Karam LB, Nahmod K, Makedonas G, Mace EM, Sorte HS, Perminow G, Rao VK, O'Connell MP, Price S, Su HC, Butrick M, McElwee J, Hughes JD, Willet J, Swan D, Xu Y, Santibanez-Koref M, Slowik V, Dinwiddie DL, Ciaccio CE, Saunders CJ, Septer S, Kingsmore SF, White AJ, Cant AJ, Hambleton S, Cooper MA) Blood 2015 Jan 22;125(4):591-9       426 Citations
1Regulatory T cells: exosomes deliver tolerance. (Chatila TA, Williams CB) Immunity 2014 Jul 17;41(1):3-5       26 Citations
2Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. (Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA Jr) Am J Physiol Regul Integr Comp Physiol 2014 Sep 15;307(6):R608-20       24 Citations
1Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60. (Xiao Y, Nagai Y, Deng G, Ohtani T, Zhu Z, Zhou Z, Zhang H, Ji MQ, Lough JW, Samanta A, Hancock WW, Greene MI) Cell Rep 2014 Jun 12;7(5):1471-1480       83 Citations
2Mice with an absent stress response are protected against ischemic renal injury. (Sreedharan R, Chen S, Miller M, Haribhai D, Williams CB, Van Why SK) Kidney Int 2014 Sep;86(3):515-24       10 Citations
1Rapid tolerance induction by hematopoietic progenitor cells in the absence of donor-matched lymphoid cells. (Domen J, Li Y, Sun L, Simpson P, Gandy K) Transpl Immunol 2014 Aug;31(2):112-8       1 Citation
3Molecular signatures differentiate immune states in type 1 diabetic families. (Chen YG, Cabrera SM, Jia S, Kaldunski ML, Kramer J, Cheong S, Geoffrey R, Roethle MF, Woodliff JE, Greenbaum CJ, Wang X, Hessner MJ) Diabetes 2014 Nov;63(11):3960-73       54 Citations
1Tolerance induction between two different strains of parental mice prevents graft-versus-host disease in haploidentical hematopoietic stem cell transplantation to F1 mice. (Guo Y, Zhang L, Wan S, Sun X, Wu Y, Yu XZ, Xia CQ) Biochem Biophys Res Commun 2014 Apr 18;446(4):1035-41       2 Citations
1Editorial: Optimizing iTreg differentiation: STATs in the balance. (Williams CB, Chatila TA) J Leukoc Biol 2014 Feb;95(2):197-8       2 Citations
2Regulation of antiviral CD8 T-cell responses. (Kulinski JM, Tarakanova VL, Verbsky J) Crit Rev Immunol 2013;33(6):477-88       21 Citations
1Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders: an evolving web of heritable autoimmune diseases. (Verbsky JW, Chatila TA) Curr Opin Pediatr 2013 Dec;25(6):708-14       143 Citations
4Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression. (Schmitt EG, Haribhai D, Jeschke JC, Co DO, Ziegelbauer J, Yan K, Iwakura Y, Mishra MK, Simpson P, Salzman NH, Williams CB) J Immunol 2013 Dec 01;191(11):5460-76       4 Citations
1STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity. (Betts BC, Veerapathran A, Pidala J, Yu XZ, Anasetti C) J Leukoc Biol 2014 Feb;95(2):205-13       28 Citations
1B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia. (Feldman AG, Tucker RM, Fenner EK, Pelanda R, Mack CL) PLoS One 2013;8(8):e73644       37 Citations
3Gene targeting in NOD mouse embryos using zinc-finger nucleases. (Chen YG, Forsberg MH, Khaja S, Ciecko AE, Hessner MJ, Geurts AM) Diabetes 2014 Jan;63(1):68-74       23 Citations
1T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea. (Tan HL, Gozal D, Samiei A, Bhattacharjee R, Wang Y, Ramirez HM, Bandla HP, Kulkarni R, Kheirandish-Gozal L) PLoS One 2013;8(7):e69710       20 Citations
1Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease. (Veerapathran A, Pidala J, Beato F, Betts B, Kim J, Turner JG, Hellerstein MK, Yu XZ, Janssen W, Anasetti C) Blood 2013 Sep 26;122(13):2251-61       38 Citations
1The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. (Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C) Nat Immunol 2013 Jul;14(7):732-40       107 Citations
1c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice. (Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ) Eur J Immunol 2013 Sep;43(9):2327-37       19 Citations
1Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia. (Tucker RM, Feldman AG, Fenner EK, Mack CL) J Hepatol 2013 Oct;59(4):790-6       56 Citations
1Induced and natural regulatory T cells in the development of inflammatory bowel disease. (Mayne CG, Williams CB) Inflamm Bowel Dis 2013 Jul;19(8):1772-88       147 Citations
1Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes. (Cabrera SM, Colvin SC, Tersey SA, Maier B, Nadler JL, Mirmira RG) Clin Exp Immunol 2013 Jun;172(3):375-82       32 Citations
1Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. (Uzel G, Sampaio EP, Lawrence MG, Hsu AP, Hackett M, Dorsey MJ, Noel RJ, Verbsky JW, Freeman AF, Janssen E, Bonilla FA, Pechacek J, Chandrasekaran P, Browne SK, Agharahimi A, Gharib AM, Mannurita SC, Yim JJ, Gambineri E, Torgerson T, Tran DQ, Milner JD, Holland SM) J Allergy Clin Immunol 2013 Jun;131(6):1611-23       255 Citations
1Fox family ties. (Williams CB, Chatila TA) Cell Res 2013 Apr;23(4):452-4       2 Citations
7IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy. (Schmitt EG, Haribhai D, Williams JB, Aggarwal P, Jia S, Charbonnier LM, Yan K, Lorier R, Turner A, Ziegelbauer J, Georgiev P, Simpson P, Salzman NH, Hessner MJ, Broeckel U, Chatila TA, Williams CB) J Immunol 2012 Dec 15;189(12):5638-48       71 Citations
1The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct. (Relland LM, Williams JB, Relland GN, Haribhai D, Ziegelbauer J, Yassai M, Gorski J, Williams CB) J Immunol 2012 Oct 01;189(7):3566-74       23 Citations
2Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner. (Xiong Y, Khanna S, Grzenda AL, Sarmento OF, Svingen PA, Lomberk GA, Urrutia RA, Faubion WA Jr) J Biol Chem 2012 Oct 05;287(41):34372-85       53 Citations
1Expansion of follicular helper T cells in the absence of Treg cells: implications for loss of B-cell anergy. (Leonardo SM, De Santis JL, Gehrand A, Malherbe LP, Gauld SB) Eur J Immunol 2012 Oct;42(10):2597-607       22 Citations
1Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. (Cabrera SM, Rigby MR, Mirmira RG) Curr Mol Med 2012 Dec;12(10):1261-72       45 Citations
2CD8+ Foxp3+ regulatory T cells are induced during graft-versus-host disease and mitigate disease severity. (Beres AJ, Haribhai D, Chadwick AC, Gonyo PJ, Williams CB, Drobyski WR) J Immunol 2012 Jul 01;189(1):464-74       96 Citations
3Requirements for growth and IL-10 expression of highly purified human T regulatory cells. (Bonacci B, Edwards B, Jia S, Williams CB, Hessner MJ, Gauld SB, Verbsky JW) J Clin Immunol 2012 Oct;32(5):1118-28       11 Citations
1Cutting edge: in the absence of regulatory T cells, a unique Th cell population expands and leads to a loss of B cell anergy. (Leonardo SM, De Santis JL, Malherbe LP, Gauld SB) J Immunol 2012 Jun 01;188(11):5223-6       13 Citations
2A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand. (Ray A, Basu S, Williams CB, Salzman NH, Dittel BN) J Immunol 2012 Apr 01;188(7):3188-98       221 Citations
1The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. (Amarnath S, Mangus CW, Wang JC, Wei F, He A, Kapoor V, Foley JE, Massey PR, Felizardo TC, Riley JL, Levine BL, June CH, Medin JA, Fowler DH) Sci Transl Med 2011 Nov 30;3(111):111ra120       358 Citations
1Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells. (Brindley SM, Lanham AM, Karrer FM, Tucker RM, Fontenot AP, Mack CL) Hepatology 2012 Apr;55(4):1130-8       97 Citations
1Granzyme B regulates antiviral CD8+ T cell responses. (Salti SM, Hammelev EM, Grewal JL, Reddy ST, Zemple SJ, Grossman WJ, Grayson MH, Verbsky JW) J Immunol 2011 Dec 15;187(12):6301-9       64 Citations
1T-regulatory cells in primary immune deficiencies. (Verbsky JW, Chatila TA) Curr Opin Allergy Clin Immunol 2011 Dec;11(6):539-44       23 Citations
1Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly. (Veerapathran A, Pidala J, Beato F, Yu XZ, Anasetti C) Blood 2011 Nov 17;118(20):5671-80       113 Citations
4A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. (Haribhai D, Williams JB, Jia S, Nickerson D, Schmitt EG, Edwards B, Ziegelbauer J, Yassai M, Li SH, Relland LM, Wise PM, Chen A, Zheng YQ, Simpson PM, Gorski J, Salzman NH, Hessner MJ, Chatila TA, Williams CB) Immunity 2011 Jul 22;35(1):109-22       353 Citations
1Instability of Foxp3 expression limits the ability of induced regulatory T cells to mitigate graft versus host disease. (Beres A, Komorowski R, Mihara M, Drobyski WR) Clin Cancer Res 2011 Jun 15;17(12):3969-83       80 Citations
1Depletion of CD25⁺ T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma. (Jing W, Yan X, Hallett WH, Gershan JA, Johnson BD) Blood 2011 Jun 23;117(25):6952-62       38 Citations
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1Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling. (Semple K, Nguyen A, Yu Y, Wang H, Anasetti C, Yu XZ) Blood 2011 Mar 17;117(11):3096-103       73 Citations
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1A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes. (Scheuplein F, Rissiek B, Driver JP, Chen YG, Koch-Nolte F, Serreze DV) J Autoimmun 2010 Mar;34(2):145-54       29 Citations
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1Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory. (Jing W, Gershan JA, Johnson BD) Blood 2009 Apr 30;113(18):4449-57       39 Citations
1Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression. (Relland LM, Mishra MK, Haribhai D, Edwards B, Ziegelbauer J, Williams CB) J Immunol 2009 Feb 01;182(3):1341-50       25 Citations
1Ethylenecarbodiimide-coupled allogeneic antigen presenting cells induce human CD4+ regulatory T cells. (Albert MH, Yu XZ, Magg T) Clin Immunol 2008 Dec;129(3):381-93       2 Citations
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1Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells. (Hippen KL, Harker-Murray P, Porter SB, Merkel SC, Londer A, Taylor DK, Bina M, Panoskaltsis-Mortari A, Rubinstein P, Van Rooijen N, Golovina TN, Suhoski MM, Miller JS, Wagner JE, June CH, Riley JL, Blazar BR) Blood 2008 Oct 01;112(7):2847-57       128 Citations
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3Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease. (Chen X, Vodanovic-Jankovic S, Johnson B, Keller M, Komorowski R, Drobyski WR) Blood 2007 Nov 15;110(10):3804-13       206 Citations
1CD25+ regulatory T cell inhibition enhances vaccine-induced immunity to neuroblastoma. (Johnson BD, Jing W, Orentas RJ) J Immunother 2007;30(2):203-14       55 Citations
1Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis. (Keever-Taylor CA, Browning MB, Johnson BD, Truitt RL, Bredeson CN, Behn B, Tsao A) Cytotherapy 2007;9(2):144-57       41 Citations
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1Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen. (Zheng J, Kohler ME, Chen Q, Weber J, Khan J, Johnson BD, Orentas RJ) BMC Immunol 2007 Mar 30;8:4       11 Citations
1Induction of immunity to neuroblastoma early after syngeneic hematopoietic stem cell transplantation using a novel mouse tumor vaccine. (Jing W, Orentas RJ, Johnson BD) Biol Blood Marrow Transplant 2007 Mar;13(3):277-92       19 Citations
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1Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion. (Chen J, Chen YG, Reifsnyder PC, Schott WH, Lee CH, Osborne M, Scheuplein F, Haag F, Koch-Nolte F, Serreze DV, Leiter EH) J Immunol 2006 Apr 15;176(8):4590-9       52 Citations
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1Graft-versus-leukemia and graft-versus-host reactions after donor lymphocyte infusion are initiated by host-type antigen-presenting cells and regulated by regulatory T cells in early and long-term chimeras. (Xia G, Truitt RL, Johnson BD) Biol Blood Marrow Transplant 2006 Apr;12(4):397-407       57 Citations
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