Medical College of Wisconsin
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Melinda R. Dwinell PhD

Melinda R. Dwinell PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Physiology
Program: Genetics

Member of the Cancer Center
Member of the Cardiovascular Center
Member of the Mellowes Center for Genomic Sciences and Precision Medicine

View Curriculum Vitae

Research Experience

  • Cardiovascular Physiological Phenomena
  • Circulatory and Respiratory Physiological Phenomena
  • Data Mining
  • Database Management Systems
  • Disease Models, Animal
  • Genetic Predisposition to Disease
  • Genome
  • Phenotype
  • Rats, Inbred Strains
  • Respiratory Physiological Phenomena

    • Methodologies and Techniques

  • Airway Resistance
  • Monitoring, Physiologic
  • Plethysmography, Whole Body

    • MCW Program / Core Facilities

  • Rat Research Models Service Center

    • Publications (121)

  • Construction and evaluation of a new rat reference genome assembly, GRCr8, from long reads and long-range scaffolding. (Li K, Smith ML, Blazier JC, Kochan KJ, Wood JMD, Howe K, Kwitek AE, Dwinell MR, Chen H, Ciosek JL, Masterson P, Murphy TD, Kalbfleisch TS, Doris PA) Genome Res 2024 Nov 08 PMID: 39516046 11/13/2024    
  • A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. (de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H) Cell Genom 2024 Apr 10;4(4):100527 PMID: 38537634 PMCID: PMC11019364 SCOPUS ID: 2-s2.0-85189630510 03/28/2024    
  • The Power of the Heterogeneous Stock Rat Founder Strains in Modeling Metabolic Disease. (Wagner VA, Holl KL, Clark KC, Reho JJ, Lehmler HJ, Wang K, Grobe JL, Dwinell MR, Raff H, Kwitek AE) Endocrinology 2023 Nov 02;164(12) PMID: 37882530 PMCID: PMC10637104 SCOPUS ID: 2-s2.0-85176509096 10/26/2023    
  • The Rat Genome Database: Genetic, Genomic, and Phenotypic Data Across Multiple Species. (Laulederkind SJF, Hayman GT, Wang SJ, Kaldunski ML, Vedi M, Demos WM, Tutaj M, Smith JR, Lamers L, Gibson AC, Thorat K, Thota J, Tutaj MA, de Pons JL, Dwinell MR, Kwitek AE) Curr Protoc 2023 Jun;3(6):e804 PMID: 37347557 PMCID: PMC10335880 SCOPUS ID: 2-s2.0-85162756259 06/22/2023    
  • A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. (de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H) bioRxiv 2023 Sep 28 PMID: 37214860 PMCID: PMC10197727 05/22/2023    
  • Genetic background in the rat affects endocrine and metabolic outcomes of bisphenol F exposure. (Wagner VA, Holl KL, Clark KC, Reho JJ, Dwinell MR, Lehmler HJ, Raff H, Grobe JL, Kwitek AE) Toxicol Sci 2023 Jun 28;194(1):84-100 PMID: 37191987 PMCID: PMC10306406 SCOPUS ID: 2-s2.0-85164065947 05/16/2023       2 Citations
  • Rare disease research resources at the Rat Genome Database. (Kaldunski ML, Smith JR, Brodie KC, De Pons JL, Demos WM, Gibson AC, Hayman GT, Lamers L, Laulederkind SJF, Thorat K, Thota J, Tutaj MA, Tutaj M, Vedi M, Wang SJ, Zacher S, Dwinell MR, Kwitek AE) Genetics 2023 Aug 09;224(4) PMID: 37119810 PMCID: PMC10411567 SCOPUS ID: 2-s2.0-85167481442 04/30/2023       3 Citations
  • Divergent risky decision-making and impulsivity behaviors in Lewis rat substrains with low genetic difference. (Gabriel DBK, Liley AE, Franks HT, Minnes GL, Tutaj M, Dwinell MR, de Jong TV, Williams RW, Mulligan MK, Chen H, Simon NW) Behav Neurosci 2023 Aug;137(4):254-267 PMID: 37104777 PMCID: PMC10524952 SCOPUS ID: 2-s2.0-85158841983 04/27/2023    
  • 2022 updates to the Rat Genome Database: a Findable, Accessible, Interoperable, and Reusable (FAIR) resource. (Vedi M, Smith JR, Thomas Hayman G, Tutaj M, Brodie KC, De Pons JL, Demos WM, Gibson AC, Kaldunski ML, Lamers L, Laulederkind SJF, Thota J, Thorat K, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE) Genetics 2023 May 04;224(1) PMID: 36930729 PMCID: PMC10474928 SCOPUS ID: 2-s2.0-85159551813 03/18/2023       12 Citations
  • The Gene Ontology knowledgebase in 2023. (Gene Ontology Consortium, Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, Ebert D, Feuermann M, Gaudet P, Harris NL, Hill DP, Lee R, Mi H, Moxon S, Mungall CJ, Muruganugan A, Mushayahama T, Sternberg PW, Thomas PD, Van Auken K, Ramsey J, Siegele DA, Chisholm RL, Fey P, Aspromonte MC, Nugnes MV, Quaglia F, Tosatto S, Giglio M, Nadendla S, Antonazzo G, Attrill H, Dos Santos G, Marygold S, Strelets V, Tabone CJ, Thurmond J, Zhou P, Ahmed SH, Asanitthong P, Luna Buitrago D, Erdol MN, Gage MC, Ali Kadhum M, Li KYC, Long M, Michalak A, Pesala A, Pritazahra A, Saverimuttu SCC, Su R, Thurlow KE, Lovering RC, Logie C, Oliferenko S, Blake J, Christie K, Corbani L, Dolan ME, Drabkin HJ, Hill DP, Ni L, Sitnikov D, Smith C, Cuzick A, Seager J, Cooper L, Elser J, Jaiswal P, Gupta P, Jaiswal P, Naithani S, Lera-Ramirez M, Rutherford K, Wood V, De Pons JL, Dwinell MR, Hayman GT, Kaldunski ML, Kwitek AE, Laulederkind SJF, Tutaj MA, Vedi M, Wang SJ, D'Eustachio P, Aimo L, Axelsen K, Bridge A, Hyka-Nouspikel N, Morgat A, Aleksander SA, Cherry JM, Engel SR, Karra K, Miyasato SR, Nash RS, Skrzypek MS, Weng S, Wong ED, Bakker E, Berardini TZ, Reiser L, Auchincloss A, Axelsen K, Argoud-Puy G, Blatter MC, Boutet E, Breuza L, Bridge A, Casals-Casas C, Coudert E, Estreicher A, Livia Famiglietti M, Feuermann M, Gos A, Gruaz-Gumowski N, Hulo C, Hyka-Nouspikel N, Jungo F, Le Mercier P, Lieberherr D, Masson P, Morgat A, Pedruzzi I, Pourcel L, Poux S, Rivoire C, Sundaram S, Bateman A, Bowler-Barnett E, Bye-A-Jee H, Denny P, Ignatchenko A, Ishtiaq R, Lock A, Lussi Y, Magrane M, Martin MJ, Orchard S, Raposo P, Speretta E, Tyagi N, Warner K, Zaru R, Diehl AD, Lee R, Chan J, Diamantakis S, Raciti D, Zarowiecki M, Fisher M, James-Zorn C, Ponferrada V, Zorn A, Ramachandran S, Ruzicka L, Westerfield M) Genetics 2023 May 04;224(1) PMID: 36866529 PMCID: PMC10158837 SCOPUS ID: 2-s2.0-85164785564 03/04/2023       558 Citations
  • A "Four Core Genotypes" rat model to distinguish mechanisms underlying sex-biased phenotypes and diseases. (Arnold AP, Chen X, Grzybowski MN, Ryan JM, Sengelaub DR, Mohanroy T, Furlan VA, Grisham W, Malloy L, Takizawa A, Wiese CB, Vergnes L, Skaletsky H, Page DC, Reue K, Harley VR, Dwinell MR, Geurts AM) bioRxiv 2023 Feb 10 PMID: 36798326 PMCID: PMC9934672 02/18/2023    
  • Ontological Analysis of Coronavirus Associated Human Genes at the COVID-19 Disease Portal. (Wang SJ, Brodie KC, De Pons JL, Demos WM, Gibson AC, Hayman GT, Hill ML, Kaldunski ML, Lamers L, Laulederkind SJF, Nalabolu HS, Thota J, Thorat K, Tutaj MA, Tutaj M, Vedi M, Zacher S, Smith JR, Dwinell MR, Kwitek AE) Genes (Basel) 2022 Dec 07;13(12) PMID: 36553571 PMCID: PMC9777590 SCOPUS ID: 2-s2.0-85144670256 12/24/2022       1 Citation
  • Lack of xanthine dehydrogenase leads to a remarkable renal decline in a novel hypouricemic rat model. (Dissanayake LV, Zietara A, Levchenko V, Spires DR, Burgos Angulo M, El-Meanawy A, Geurts AM, Dwinell MR, Palygin O, Staruschenko A) iScience 2022 Sep 16;25(9):104887 PMID: 36039296 PMCID: PMC9418856 SCOPUS ID: 2-s2.0-85136236916 08/31/2022       8 Citations
  • Body Composition and Metabolic Changes in a Lyon Hypertensive Congenic Rat and Identification of Ercc6l2 as a Positional Candidate Gene. (Clark KC, Wagner VA, Holl KL, Reho JJ, Tutaj M, Smith JR, Dwinell MR, Grobe JL, Kwitek AE) Front Genet 2022;13:903971 PMID: 35812759 PMCID: PMC9263446 SCOPUS ID: 2-s2.0-85134024483 07/12/2022       1 Citation
  • Btg2 mutation induces renal injury and impairs blood pressure control in female rats. (Hoffman MJ, Takizawa A, Jensen ES, Schilling R, Grzybowski M, Geurts AM, Dwinell MR) Physiol Genomics 2022 Jul 01;54(7):231-241 PMID: 35503009 PMCID: PMC9208437 SCOPUS ID: 2-s2.0-85132453480 05/04/2022       2 Citations
  • MOET: a web-based gene set enrichment tool at the Rat Genome Database for multiontology and multispecies analyses. (Vedi M, Nalabolu HS, Lin CW, Hoffman MJ, Smith JR, Brodie K, De Pons JL, Demos WM, Gibson AC, Hayman GT, Hill ML, Kaldunski ML, Lamers L, Laulederkind SJF, Thorat K, Thota J, Tutaj M, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE) Genetics 2022 Apr 04;220(4) PMID: 35380657 PMCID: PMC8982048 SCOPUS ID: 2-s2.0-85128160560 04/06/2022       7 Citations
  • The Rat Genome Database (RGD) facilitates genomic and phenotypic data integration across multiple species for biomedical research. (Kaldunski ML, Smith JR, Hayman GT, Brodie K, De Pons JL, Demos WM, Gibson AC, Hill ML, Hoffman MJ, Lamers L, Laulederkind SJF, Nalabolu HS, Thorat K, Thota J, Tutaj M, Tutaj MA, Vedi M, Wang SJ, Zacher S, Dwinell MR, Kwitek AE) Mamm Genome 2022 Mar;33(1):66-80 PMID: 34741192 PMCID: PMC8570235 SCOPUS ID: 2-s2.0-85118526605 11/07/2021       12 Citations
  • The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769 (Howe K, Dwinell M, Shimoyama M, Corton C, Betteridge E, Dove A, Quail MA, Smith M, Saba L, Williams RW, Chen H, Kwitek AE, McCarthy SA, Uliano-Silva M, Chow W, Tracey A, Torrance J, Sims Y, Challis R, Threlfall J, Blaxter M)) Wellcome Open Res 2021, 6:118 05/18/2021    
  • The NIH Somatic Cell Genome Editing program. (Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J, SCGE Consortium) Nature 2021 Apr;592(7853):195-204 PMID: 33828315 PMCID: PMC8026397 SCOPUS ID: 2-s2.0-85103997956 04/09/2021       86 Citations
  • The genome sequence of the Norway rat, Rattus norvegicus Berkenhout 1769 (Howe K, Dwinell M, Shimoyama M, Corton C, Betteridge E, Dove A, Quail MA, Smith M, Saba L, Williams RW, Chen H, Kwitek AE, McCarthy SA, Uliano-Silva M, Chow W, Tracey A, Torrance J, Sims Y, Challis R, Threlfall J, Blaxter M) Wellcome Open Research 2021;6 SCOPUS ID: 2-s2.0-85111510510 01/01/2021       15 Citations
  • The Gene Ontology resource: enriching a GOld mine. (Gene Ontology Consortium) Nucleic Acids Res 2021 Jan 08;49(D1):D325-D334 PMID: 33290552 PMCID: PMC7779012 SCOPUS ID: 2-s2.0-85099428896 12/09/2020       2094 Citations
  • Sexual Dimorphic Role of CD14 (Cluster of Differentiation 14) in Salt-Sensitive Hypertension and Renal Injury. (Fehrenbach DJ, Abais-Battad JM, Dasinger JH, Lund H, Keppel T, Zemaj J, Cherian-Shaw M, Gundry RL, Geurts AM, Dwinell MR, Mattson DL) Hypertension 2021 Jan;77(1):228-240 PMID: 33249861 PMCID: PMC9732708 SCOPUS ID: 2-s2.0-85097815793 12/01/2020       8 Citations
  • Mutation of RORγT reveals a role for Th17 cells in both injury and recovery from renal ischemia-reperfusion injury. (Mehrotra P, Ullah MM, Collett JA, Myers SL, Dwinell MR, Geurts AM, Basile DP) Am J Physiol Renal Physiol 2020 Nov 01;319(5):F796-F808 PMID: 32924545 PMCID: PMC7789982 SCOPUS ID: 2-s2.0-85094221372 09/15/2020       14 Citations
  • Transcriptional analysis of the multiple Sry genes and developmental program at the onset of testis differentiation in the rat. (Prokop JW, Chhetri SB, van Veen JE, Chen X, Underwood AC, Uhl K, Dwinell MR, Geurts AM, Correa SM, Arnold AP) Biol Sex Differ 2020 May 12;11(1):28 PMID: 32398044 PMCID: PMC7216353 SCOPUS ID: 2-s2.0-85084627810 05/14/2020       6 Citations
  • Chromosomal Substitution Strategies to Localize Genomic Regions Related to Complex Traits. (Cowley AW Jr, Dwinell MR) Compr Physiol 2020 Mar 12;10(2):365-388 PMID: 32163204 SCOPUS ID: 2-s2.0-85081890516 03/13/2020       6 Citations
  • Robust and replicable measurement for prepulse inhibition of the acoustic startle response. (Miller EA, Kastner DB, Grzybowski MN, Dwinell MR, Geurts AM, Frank LM) Mol Psychiatry 2021 Jun;26(6):1909-1927 PMID: 32144356 PMCID: PMC7483293 SCOPUS ID: 2-s2.0-85081733376 03/08/2020       17 Citations
  • The Year of the Rat: The Rat Genome Database at 20: a multi-species knowledgebase and analysis platform. (Smith JR, Hayman GT, Wang SJ, Laulederkind SJF, Hoffman MJ, Kaldunski ML, Tutaj M, Thota J, Nalabolu HS, Ellanki SLR, Tutaj MA, De Pons JL, Kwitek AE, Dwinell MR, Shimoyama ME) Nucleic Acids Res 2020 Jan 08;48(D1):D731-D742 PMID: 31713623 PMCID: PMC7145519 SCOPUS ID: 2-s2.0-85077666371 11/13/2019       104 Citations
  • Precision Medicine and Precision Public Health: Academic Education and Community Engagement. (Meurer JR, Whittle JC, Lamb KM, Kosasih MA, Dwinell MR, Urrutia RA) Am J Prev Med 2019 Aug;57(2):286-289 PMID: 31326012 SCOPUS ID: 2-s2.0-85068737878 07/22/2019       4 Citations
  • Rat Genome Databases, Repositories, and Tools. (Laulederkind SJF, Hayman GT, Wang SJ, Hoffman MJ, Smith JR, Bolton ER, De Pons J, Tutaj MA, Tutaj M, Thota J, Dwinell MR, Shimoyama M) Methods Mol Biol 2019;2018:71-96 PMID: 31228152 SCOPUS ID: 2-s2.0-85068143710 06/23/2019       15 Citations
  • The Rat: A Model Used in Biomedical Research. (Smith JR, Bolton ER, Dwinell MR) Methods Mol Biol 2019;2018:1-41 PMID: 31228150 SCOPUS ID: 2-s2.0-85068179700 06/23/2019       20 Citations
  • Quantitative phenotype analysis to identify, validate and compare rat disease models. (Zhao Y, Smith JR, Wang SJ, Dwinell MR, Shimoyama M) Database (Oxford) 2019 Jan 01;2019 PMID: 30938777 PMCID: PMC6444380 SCOPUS ID: 2-s2.0-85064202973 04/03/2019       3 Citations
  • Identification of a Rat Mammary Tumor Risk Locus That Is Syntenic with the Commonly Amplified 8q12.1 and 8q22.1 Regions in Human Breast Cancer Patients. (Plasterer C, Tsaih SW, Lemke A, Schilling R, Dwinell M, Rau A, Auer P, Rui H, Flister MJ) G3 (Bethesda) 2019 May 07;9(5):1739-1743 PMID: 30914425 PMCID: PMC6505137 SCOPUS ID: 2-s2.0-85065792535 03/28/2019       4 Citations
  • Integrated curation and data mining for disease and phenotype models at the Rat Genome Database. (Wang SJ, Laulederkind SJF, Zhao Y, Hayman GT, Smith JR, Tutaj M, Thota J, Tutaj MA, Hoffman MJ, Bolton ER, De Pons J, Dwinell MR, Shimoyama M) Database (Oxford) 2019 Jan 01;2019 PMID: 30753478 PMCID: PMC6369425 SCOPUS ID: 2-s2.0-85061482732 02/13/2019       1 Citation
  • Integrating biology with rat genomic tools (Dwinell MR, Geurts AM) The Laboratory Rat 1 January 2019:811-825 SCOPUS ID: 2-s2.0-85094602754 01/01/2019    
  • The Gene Ontology Resource: 20 years and still GOing strong. (The Gene Ontology Consortium) Nucleic Acids Res 2019 Jan 08;47(D1):D330-D338 PMID: 30395331 PMCID: PMC6323945 SCOPUS ID: 2-s2.0-85059799086 11/06/2018       2959 Citations
  • Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities. (Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW) J Neuropathol Exp Neurol 2018 Aug 01;77(8):665-672 PMID: 29850869 PMCID: PMC6044411 SCOPUS ID: 2-s2.0-85054028838 06/01/2018       7 Citations
  • A Primer for the Rat Genome Database (RGD). (Laulederkind SJF, Hayman GT, Wang SJ, Smith JR, Petri V, Hoffman MJ, De Pons J, Tutaj MA, Ghiasvand O, Tutaj M, Thota J, Dwinell MR, Shimoyama M) Methods Mol Biol 2018;1757:163-209 PMID: 29761460 PMCID: PMC6487669 SCOPUS ID: 2-s2.0-85047123695 05/16/2018       10 Citations
  • Rat Genome and Model Resources. (Shimoyama M, Smith JR, Bryda E, Kuramoto T, Saba L, Dwinell M) ILAR J 2017 Jul 01;58(1):42-58 PMID: 28838068 PMCID: PMC6057551 SCOPUS ID: 2-s2.0-85028342548 08/26/2017       31 Citations
  • Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts. (Hirabayashi M, Hara H, Goto T, Takizawa A, Dwinell MR, Yamanaka T, Hochi S, Nakauchi H) J Reprod Dev 2017 Dec 15;63(6):611-616 PMID: 28824040 PMCID: PMC5735273 SCOPUS ID: 2-s2.0-85040115487 08/22/2017       3 Citations
  • Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer. (Flister MJ, Tsaih SW, Stoddard A, Plasterer C, Jagtap J, Parchur AK, Sharma G, Prisco AR, Lemke A, Murphy D, Al-Gizawiy M, Straza M, Ran S, Geurts AM, Dwinell MR, Greene AS, Bergom C, LaViolette PS, Joshi A) Breast Cancer Res Treat 2017 Aug;165(1):53-64 PMID: 28567545 PMCID: PMC6404538 SCOPUS ID: 2-s2.0-85020059895 06/02/2017       15 Citations
  • Lung injury pathways: Adenosine receptor 2B signaling limits development of ischemic bronchiolitis obliterans organizing pneumonia. (Densmore JC, Schaid TR, Jeziorczak PM, Medhora M, Audi S, Nayak S, Auchampach J, Dwinell MR, Geurts AM, Jacobs ER) Exp Lung Res 2017 Feb;43(1):38-48 PMID: 28266889 PMCID: PMC5831175 SCOPUS ID: 2-s2.0-85014510215 03/08/2017       6 Citations
  • Expansion of the Gene Ontology knowledgebase and resources. (The Gene Ontology Consortium) Nucleic Acids Res 2017 Jan 04;45(D1):D331-D338 PMID: 27899567 PMCID: PMC5210579 SCOPUS ID: 2-s2.0-85016166168 12/03/2016       1391 Citations
  • Exploring human disease using the Rat Genome Database. (Shimoyama M, Laulederkind SJ, De Pons J, Nigam R, Smith JR, Tutaj M, Petri V, Hayman GT, Wang SJ, Ghiasvand O, Thota J, Dwinell MR) Dis Model Mech 2016 Oct 01;9(10):1089-1095 PMID: 27736745 PMCID: PMC5087824 SCOPUS ID: 2-s2.0-84993949779 10/14/2016       28 Citations
  • Disease, Models, Variants and Altered Pathways-Journeying RGD Through the Magnifying Glass. (Petri V, Hayman GT, Tutaj M, Smith JR, Laulederkind S, Wang SJ, Nigam R, De Pons J, Shimoyama M, Dwinell MR) Comput Struct Biotechnol J 2016;14:35-48 PMID: 27602200 PMCID: PMC4700298 SCOPUS ID: 2-s2.0-84961710673 09/08/2016       2 Citations
  • Comprehensive coverage of cardiovascular disease data in the disease portals at the Rat Genome Database. (Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Smith JR, Tutaj M, Nigam R, Dwinell MR, Shimoyama M) Physiol Genomics 2016 Aug 01;48(8):589-600 PMID: 27287925 PMCID: PMC5005459 SCOPUS ID: 2-s2.0-84983740999 06/12/2016       3 Citations
  • The Disease Portals, disease-gene annotation and the RGD disease ontology at the Rat Genome Database. (Hayman GT, Laulederkind SJ, Smith JR, Wang SJ, Petri V, Nigam R, Tutaj M, De Pons J, Dwinell MR, Shimoyama M) Database (Oxford) 2016;2016 PMID: 27009807 PMCID: PMC4805243 SCOPUS ID: 2-s2.0-84964901900 03/25/2016       17 Citations
  • Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges. (Maric-Bilkan C, Arnold AP, Taylor DA, Dwinell M, Howlett SE, Wenger N, Reckelhoff JF, Sandberg K, Churchill G, Levin E, Lundberg MS) Hypertension 2016 May;67(5):802-7 PMID: 26975706 PMCID: PMC4833564 SCOPUS ID: 2-s2.0-84961233476 03/16/2016       56 Citations
  • Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. (Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M) J Am Heart Assoc 2016 Feb 17;5(2) PMID: 26888427 PMCID: PMC4802485 SCOPUS ID: 2-s2.0-84995488392 02/19/2016       46 Citations
  • The phenotypic impact of the male-specific region of chromosome-Y in inbred mating: the role of genetic variants and gene duplications in multiple inbred rat strains. (Prokop JW, Tsaih SW, Faber AB, Boehme S, Underwood AC, Troyer S, Playl L, Milsted A, Turner ME, Ely D, Martins AS, Tutaj M, Lazar J, Dwinell MR, Jacob HJ) Biol Sex Differ 2016;7:10 PMID: 26848384 PMCID: PMC4740989 SCOPUS ID: 2-s2.0-84957567774 02/06/2016       14 Citations
  • Rat Breeding Parameters According to Floor Space Available in Cage. (Allen KP, Dwinell MR, Zappa AM, Michaels AM, Murray KM, Thulin JD) J Am Assoc Lab Anim Sci 2016 Jan;55(1):21-4 PMID: 26817975 PMCID: PMC4747006 SCOPUS ID: 2-s2.0-84958177394 01/29/2016       6 Citations
  • Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. (Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA) Purinergic Signal 2015 Dec;11(4):519-31 PMID: 26385692 PMCID: PMC4648794 SCOPUS ID: 2-s2.0-84947616348 09/20/2015       9 Citations
  • 2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. (Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A, International Committee on Standardized Genetic Nomenclature for Mice, Rat Genome and Nomenclature Committee) J Cardiovasc Transl Res 2015 Jun;8(4):269-77 PMID: 25920443 PMCID: PMC4475456 SCOPUS ID: 2-s2.0-84931568348 04/30/2015       22 Citations
  • PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease. (Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Liu W, Smith JR, Nigam R, Dwinell MR, Shimoyama M) Database (Oxford) 2015;2015 PMID: 25632109 PMCID: PMC4309021 SCOPUS ID: 2-s2.0-84943179091 01/30/2015       11 Citations
  • OntoMate: a text-mining tool aiding curation at the Rat Genome Database. (Liu W, Laulederkind SJ, Hayman GT, Wang SJ, Nigam R, Smith JR, De Pons J, Dwinell MR, Shimoyama M) Database (Oxford) 2015;2015 PMID: 25619558 PMCID: PMC4305386 SCOPUS ID: 2-s2.0-85051605173 01/27/2015       20 Citations
  • Gene Ontology Consortium: going forward. (Gene Ontology Consortium) Nucleic Acids Res 2015 Jan;43(Database issue):D1049-56 PMID: 25428369 PMCID: PMC4383973 SCOPUS ID: 2-s2.0-84946735654 11/28/2014       2441 Citations
  • Enhancement of resting-state fcMRI networks by prior sensory stimulation. (Li C, Li Z, Ward BD, Dwinell MR, Lombard JH, Hudetz AG, Pawela CP) Brain Connect 2014 Nov;4(9):760-8 PMID: 25387238 PMCID: PMC4238242 SCOPUS ID: 2-s2.0-84937199899 11/12/2014       5 Citations
  • The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease. (Shimoyama M, De Pons J, Hayman GT, Laulederkind SJ, Liu W, Nigam R, Petri V, Smith JR, Tutaj M, Wang SJ, Worthey E, Dwinell M, Jacob H) Nucleic Acids Res 2015 Jan;43(Database issue):D743-50 PMID: 25355511 PMCID: PMC4383884 SCOPUS ID: 2-s2.0-84941092929 10/31/2014       171 Citations
  • Disease pathways at the Rat Genome Database Pathway Portal: genes in context-a network approach to understanding the molecular mechanisms of disease. (Petri V, Hayman GT, Tutaj M, Smith JR, Laulederkind SJ, Wang SJ, Nigam R, De Pons J, Shimoyama M, Dwinell MR, Worthey EA, Jacob HJ) Hum Genomics 2014 Sep 30;8(1):17 PMID: 25265995 PMCID: PMC4191248 SCOPUS ID: 2-s2.0-84964312855 10/01/2014       7 Citations
  • The pathway ontology - updates and applications. (Petri V, Jayaraman P, Tutaj M, Hayman GT, Smith JR, De Pons J, Laulederkind SJ, Lowry TF, Nigam R, Wang SJ, Shimoyama M, Dwinell MR, Munzenmaier DH, Worthey EA, Jacob HJ) J Biomed Semantics 2014 Feb 05;5(1):7 PMID: 24499703 PMCID: PMC3922094 SCOPUS ID: 2-s2.0-84927942575 02/07/2014       73 Citations
  • Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. (Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH) Am J Physiol Heart Circ Physiol 2014 Feb;306(3):H339-47 PMID: 24322611 PMCID: PMC3920146 SCOPUS ID: 2-s2.0-84893409421 12/11/2013       11 Citations
  • Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD. (Nigam R, Munzenmaier DH, Worthey EA, Dwinell MR, Shimoyama M, Jacob HJ) J Biomed Semantics 2013 Nov 22;4(1):36 PMID: 24267899 PMCID: PMC4177145 SCOPUS ID: 2-s2.0-84943184308 11/26/2013       12 Citations
  • The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications. (Smith JR, Park CA, Nigam R, Laulederkind SJ, Hayman GT, Wang SJ, Lowry TF, Petri V, Pons JD, Tutaj M, Liu W, Worthey EA, Shimoyama M, Dwinell MR) J Biomed Semantics 2013 Oct 08;4(1):26 PMID: 24103152 PMCID: PMC3882879 SCOPUS ID: 2-s2.0-84978081999 10/10/2013       30 Citations
  • FMRI and fcMRI phenotypes map the genomic effect of chromosome 13 in Brown Norway and Dahl salt-sensitive rats. (Li Z, Ward BD, Dwinell MR, Lombard JH, Pawela CP) Neuroimage 2014 Apr 15;90:403-12 PMID: 24084065 SCOPUS ID: 2-s2.0-84893717855 10/03/2013       4 Citations
  • Identifying multiple causative genes at a single GWAS locus. (Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C) Genome Res 2013 Dec;23(12):1996-2002 PMID: 24006081 PMCID: PMC3847770 SCOPUS ID: 2-s2.0-84888132259 09/06/2013       87 Citations
  • Rat Genome Database: a unique resource for rat, human, and mouse quantitative trait locus data. (Nigam R, Laulederkind SJ, Hayman GT, Smith JR, Wang SJ, Lowry TF, Petri V, De Pons J, Tutaj M, Liu W, Jayaraman P, Munzenmaier DH, Worthey EA, Dwinell MR, Shimoyama M, Jacob HJ) Physiol Genomics 2013 Sep 16;45(18):809-16 PMID: 23881287 PMCID: PMC3783816 SCOPUS ID: 2-s2.0-84884191657 07/25/2013       23 Citations
  • Analysis of disease-associated objects at the Rat Genome Database. (Wang SJ, Laulederkind SJ, Hayman GT, Smith JR, Petri V, Lowry TF, Nigam R, Dwinell MR, Worthey EA, Munzenmaier DH, Shimoyama M, Jacob HJ) Database (Oxford) 2013;2013:bat046 PMID: 23794737 PMCID: PMC3689439 SCOPUS ID: 2-s2.0-84885941569 06/26/2013       7 Citations
  • PhenoMiner: quantitative phenotype curation at the rat genome database. (Laulederkind SJ, Liu W, Smith JR, Hayman GT, Wang SJ, Nigam R, Petri V, Lowry TF, de Pons J, Dwinell MR, Shimoyama M) Database (Oxford) 2013;2013:bat015 PMID: 23603846 PMCID: PMC3630803 SCOPUS ID: 2-s2.0-84885154580 04/23/2013       22 Citations
  • Comparison of 2 rat breeding schemes using conventional caging. (Allen KP, Dwinell MR, Zappa A, Temple A, Thulin J) J Am Assoc Lab Anim Sci 2013 Mar;52(2):142-5 PMID: 23562096 PMCID: PMC3624781 SCOPUS ID: 2-s2.0-84875539802 04/09/2013       8 Citations
  • The Rat Genome Database 2013--data, tools and users. (Laulederkind SJ, Hayman GT, Wang SJ, Smith JR, Lowry TF, Nigam R, Petri V, de Pons J, Dwinell MR, Shimoyama M, Munzenmaier DH, Worthey EA, Jacob HJ) Brief Bioinform 2013 Jul;14(4):520-6 PMID: 23434633 PMCID: PMC3713714 SCOPUS ID: 2-s2.0-84888772878 02/26/2013       56 Citations
  • The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information. (Hayman GT, Jayaraman P, Petri V, Tutaj M, Liu W, De Pons J, Dwinell MR, Shimoyama M) Hum Genomics 2013 Feb 05;7(1):4 PMID: 23379628 PMCID: PMC3598722 SCOPUS ID: 2-s2.0-84878767208 02/06/2013       7 Citations
  • Exploring genetic, genomic, and phenotypic data at the rat genome database. (Laulederkind SJF, Hayman GT, Wang SJ, Lowry TF, Nigam R, Petri V, Smith JR, Dwinell MR, Jacob HJ, Shimoyama M) Curr Protoc Bioinformatics 2012 Dec;Chapter 1:1.14.1-1.14.27 PMID: 23255149 PMCID: PMC3555435 SCOPUS ID: 2-s2.0-84875531338 12/21/2012       10 Citations
  • Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. (Basile DP, Dwinell MR, Wang SJ, Shames BD, Donohoe DL, Chen S, Sreedharan R, Van Why SK) Kidney Int 2013 Feb;83(2):242-50 PMID: 23235564 PMCID: PMC3561482 SCOPUS ID: 2-s2.0-84873411495 12/14/2012       19 Citations
  • Gene Ontology annotations and resources. (Gene Ontology Consortium, Blake JA, Dolan M, Drabkin H, Hill DP, Li N, Sitnikov D, Bridges S, Burgess S, Buza T, McCarthy F, Peddinti D, Pillai L, Carbon S, Dietze H, Ireland A, Lewis SE, Mungall CJ, Gaudet P, Chrisholm RL, Fey P, Kibbe WA, Basu S, Siegele DA, McIntosh BK, Renfro DP, Zweifel AE, Hu JC, Brown NH, Tweedie S, Alam-Faruque Y, Apweiler R, Auchinchloss A, Axelsen K, Bely B, Blatter M-, Bonilla C, Bouguerleret L, Boutet E, Breuza L, Bridge A, Chan WM, Chavali G, Coudert E, Dimmer E, Estreicher A, Famiglietti L, Feuermann M, Gos A, Gruaz-Gumowski N, Hieta R, Hinz C, Hulo C, Huntley R, James J, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, Martin MJ, Masson P, Mutowo-Muellenet P, O'Donovan C, Pedruzzi I, Pichler K, Poggioli D, Porras Millán P, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Stutz A, Sundaram S, Tognolli M, Xenarios I, Foulgar R, Lomax J, Roncaglia P, Khodiyar VK, Lovering RC, Talmud PJ, Chibucos M, Giglio MG, Chang H-, Hunter S, McAnulla C, Mitchell A, Sangrador A, Stephan R, Harris MA, Oliver SG, Rutherford K, Wood V, Bahler J, Lock A, Kersey PJ, McDowall DM, Staines DM, Dwinell M, Shimoyama M, Laulederkind S, Hayman T, Wang S-, Petri V, Lowry T, D'Eustachio P, Matthews L, Balakrishnan R, Binkley G, Cherry JM, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hitz BC, Hong EL, Karra K, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng S, Wong ED, Berardini TZ, Huala E, Mi H, Thomas PD, Chan J, Kishore R, Sternberg P, Van Auken K, Howe D, Westerfield M) Nucleic Acids Res 2013 Jan;41(Database issue):D530-5 PMID: 23161678 PMCID: PMC3531070 SCOPUS ID: 2-s2.0-84874253819 11/20/2012       466 Citations
  • Three ontologies to define phenotype measurement data. (Shimoyama M, Nigam R, McIntosh LS, Nagarajan R, Rice T, Rao DC, Dwinell MR) Front Genet 2012;3:87 PMID: 22654893 PMCID: PMC3361058 SCOPUS ID: 2-s2.0-84869772444 06/02/2012       49 Citations
  • Ontology searching and browsing at the Rat Genome Database. (Laulederkind SJ, Tutaj M, Shimoyama M, Hayman GT, Lowry TF, Nigam R, Petri V, Smith JR, Wang SJ, de Pons J, Dwinell MR, Jacob HJ) Database (Oxford) 2012;2012:bas016 PMID: 22434847 PMCID: PMC3308169 SCOPUS ID: 2-s2.0-84862262998 03/22/2012       18 Citations
  • The Gene Ontology: enhancements for 2011. (Gene Ontology Consortium) Nucleic Acids Res 2012 Jan;40(Database issue):D559-64 PMID: 22102568 PMCID: PMC3245151 SCOPUS ID: 2-s2.0-84859699831 11/22/2011       190 Citations
  • The emerging role for rat models in gene discovery. (Dwinell MR, Lazar J, Geurts AM) Mamm Genome 2011 Aug;22(7-8):466-75 PMID: 21732192 PMCID: PMC3643810 SCOPUS ID: 2-s2.0-80051552900 07/07/2011       23 Citations
  • The Rat Genome Database pathway portal. (Petri V, Shimoyama M, Hayman GT, Smith JR, Tutaj M, de Pons J, Dwinell MR, Munzenmaier DH, Twigger SN, Jacob HJ, RGD Team) Database (Oxford) 2011;2011:bar010 PMID: 21478484 PMCID: PMC3072770 SCOPUS ID: 2-s2.0-80052334281 04/12/2011       17 Citations
  • The Rat Genome Database curation tool suite: a set of optimized software tools enabling efficient acquisition, organization, and presentation of biological data. (Laulederkind SJ, Shimoyama M, Hayman GT, Lowry TF, Nigam R, Petri V, Smith JR, Wang SJ, de Pons J, Kowalski G, Liu W, Rood W, Munzenmaier DH, Dwinell MR, Twigger SN, Jacob HJ, RGD Team) Database (Oxford) 2011;2011:bar002 PMID: 21321022 PMCID: PMC3041158 SCOPUS ID: 2-s2.0-79956225148 02/16/2011       12 Citations
  • RGD: a comparative genomics platform. (Shimoyama M, Smith JR, Hayman T, Laulederkind S, Lowry T, Nigam R, Petri V, Wang SJ, Dwinell M, Jacob H, RGD Team) Hum Genomics 2011 Jan;5(2):124-9 PMID: 21296746 PMCID: PMC3222152 SCOPUS ID: 2-s2.0-79955839943 02/08/2011       22 Citations
  • Gene targeting in the rat: advances and opportunities. (Jacob HJ, Lazar J, Dwinell MR, Moreno C, Geurts AM) Trends Genet 2010 Dec;26(12):510-8 PMID: 20869786 PMCID: PMC2991520 SCOPUS ID: 2-s2.0-78549295495 09/28/2010       86 Citations
  • Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. (Kunert MP, Dwinell MR, Lombard JH) Physiol Genomics 2010 Nov 29;42A(4):244-58 PMID: 20841496 PMCID: PMC3008365 SCOPUS ID: 2-s2.0-78649724378 09/16/2010       8 Citations
  • Postnatal ventilatory response to CO₂ in awake piglets. (Dwinell MR, Hogan GE, Sirlin E, Mayhew DL, Forster HV) Respir Physiol Neurobiol 2011 Jan 31;175(1):49-54 PMID: 20837167 SCOPUS ID: 2-s2.0-78650169346 09/15/2010    
  • Online tools for understanding rat physiology. (Dwinell MR) Brief Bioinform 2010 Jul;11(4):431-9 PMID: 20056729 PMCID: PMC2905522 SCOPUS ID: 2-s2.0-77955034237 01/09/2010       15 Citations
  • The rat genome database curators: who, what, where, why. (Shimoyama M, Hayman GT, Laulederkind SJ, Nigam R, Lowry TF, Petri V, Smith JR, Wang SJ, Munzenmaier DH, Dwinell MR, Twigger SN, Jacob HJ, RGD Team) PLoS Comput Biol 2009 Nov;5(11):e1000582 PMID: 19956751 PMCID: PMC2775909 SCOPUS ID: 2-s2.0-73449141822 12/04/2009       18 Citations
  • Differences between three inbred rat strains in number of K+ channel-immunoreactive neurons in the medullary raphé nucleus. (Riley D, Dwinell M, Qian B, Krause KL, Bonis JM, Neumueller S, Marshall BD, Hodges MR, Forster HV) J Appl Physiol (1985) 2010 Apr;108(4):1003-10 PMID: 19926827 PMCID: PMC2853200 SCOPUS ID: 2-s2.0-77950571666 11/21/2009       5 Citations
  • The Rat Genome Database 2009: variation, ontologies and pathways. (Dwinell MR, Worthey EA, Shimoyama M, Bakir-Gungor B, DePons J, Laulederkind S, Lowry T, Nigram R, Petri V, Smith J, Stoddard A, Twigger SN, Jacob HJ, RGD Team) Nucleic Acids Res 2009 Jan;37(Database issue):D744-9 PMID: 18996890 PMCID: PMC2686558 SCOPUS ID: 2-s2.0-58149194606 11/11/2008       64 Citations
  • Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. (Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Jacob HJ, Cowley AW Jr) Am J Physiol Renal Physiol 2008 Sep;295(3):F837-42 PMID: 18653478 PMCID: PMC2536867 SCOPUS ID: 2-s2.0-54449084434 07/26/2008       94 Citations
  • Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. (Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2008 Aug;295(2):R516-27 PMID: 18509103 PMCID: PMC2519925 SCOPUS ID: 2-s2.0-51149109894 05/30/2008       11 Citations
  • Physiological genomics: from bench to bedside. (Dwinell MR) Exp Physiol 2007 Nov;92(6):987 PMID: 17938419 SCOPUS ID: 2-s2.0-35248832526 10/17/2007    
  • Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. (Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Cowley AW Jr, Jacob HJ) Am J Physiol Renal Physiol 2007 Dec;293(6):F1905-14 PMID: 17898042 SCOPUS ID: 2-s2.0-36549060031 09/28/2007       41 Citations
  • Postnatal developmental changes in CO2 sensitivity in rats. (Davis SE, Solhied G, Castillo M, Dwinell M, Brozoski D, Forster HV) J Appl Physiol (1985) 2006 Oct;101(4):1097-103 PMID: 16794027 SCOPUS ID: 2-s2.0-33749350208 06/24/2006       59 Citations
  • Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. (Kunert MP, Drenjancevic-Peric I, Dwinell MR, Lombard JH, Cowley AW Jr, Greene AS, Kwitek AE, Jacob HJ) Physiol Genomics 2006 Aug 16;26(3):218-25 PMID: 16772359 SCOPUS ID: 2-s2.0-33747330104 06/15/2006       25 Citations
  • BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. (Kwitek AE, Jacob HJ, Baker JE, Dwinell MR, Forster HV, Greene AS, Kunert MP, Lombard JH, Mattson DL, Pritchard KA Jr, Roman RJ, Tonellato PJ, Cowley AW Jr) Physiol Genomics 2006 Apr 13;25(2):303-13 PMID: 16478827 SCOPUS ID: 2-s2.0-33645761913 02/16/2006       29 Citations
  • Genetic determinants on rat chromosome 6 modulate variation in the hypercapnic ventilatory response using consomic strains. (Dwinell MR, Forster HV, Petersen J, Rider A, Kunert MP, Cowley AW Jr, Jacob HJ) J Appl Physiol (1985) 2005 May;98(5):1630-8 PMID: 15661838 SCOPUS ID: 2-s2.0-17644403141 01/22/2005       14 Citations
  • Do genes on rat chromosomes 9, 13, 16, 18, and 20 contribute to regulation of breathing? (Forster HV, Dwinell MR, Hodges MR, Brozoski D, Hogan GE) Respir Physiol Neurobiol 2003 May 30;135(2-3):247-61 PMID: 12809624 SCOPUS ID: 2-s2.0-0038384573 06/18/2003       15 Citations
  • Ventilatory phenotypes among four strains of adult rats. (Hodges MR, Forster HV, Papanek PE, Dwinell MR, Hogan GE) J Appl Physiol (1985) 2002 Sep;93(3):974-83 PMID: 12183493 SCOPUS ID: 2-s2.0-0036707832 08/17/2002       55 Citations
  • Central amino acid neurotransmitters, ventilatory output and metabolism during acute hypoxia in anesthetized rats. (Dwinell MR, Kazemi H, Lam JT, Powell FL) Adv Exp Med Biol 2001;499:291-6 PMID: 11729894 SCOPUS ID: 2-s2.0-0035702427 12/04/2001       1 Citation
  • Ventilatory long-term facilitation in unanesthetized rats. (Olson EB Jr, Bohne CJ, Dwinell MR, Podolsky A, Vidruk EH, Fuller DD, Powell FL, Mitchel GS) J Appl Physiol (1985) 2001 Aug;91(2):709-16 PMID: 11457785 SCOPUS ID: 2-s2.0-0034923789 07/18/2001       132 Citations
  • Measuring ventilatory acclimatization to hypoxia: comparative aspects. (Powell FL, Dwinell MR, Aaron EA) Respir Physiol 2000 Sep;122(2-3):271-84 PMID: 10967350 SCOPUS ID: 2-s2.0-0034285080 09/01/2000       50 Citations
  • Central nervous system mechanisms of ventilatory acclimatization to hypoxia. (Powell FL, Huey KA, Dwinell MR) Respir Physiol 2000 Jul;121(2-3):223-36 PMID: 10963777 SCOPUS ID: 2-s2.0-0033837261 08/30/2000       76 Citations
  • Chronic hypoxia induces changes in the central nervous system processing of arterial chemoreceptor input. (Dwinell MR, Huey KA, Powell FL) Adv Exp Med Biol 2000;475:477-84 PMID: 10849688 SCOPUS ID: 2-s2.0-0034465921 06/13/2000       14 Citations
  • Chronic hypoxia enhances the phrenic nerve response to arterial chemoreceptor stimulation in anesthetized rats. (Dwinell MR, Powell FL) J Appl Physiol (1985) 1999 Aug;87(2):817-23 PMID: 10444644 SCOPUS ID: 2-s2.0-0032841030 08/13/1999       99 Citations
  • Differential respiratory muscle recruitment induced by clonidine in awake goats. (Hedrick MS, Dwinell MR, Janssen PL, Pizarro J, Bisgard GE) J Appl Physiol (1985) 1998 Apr;84(4):1198-207 PMID: 9516185 SCOPUS ID: 2-s2.0-0031944642 05/09/1998       17 Citations
  • Central dopamine D2 receptors in the CNS are not involved in ventilatory acclimatization to hypoxia in anesthetized rats (Dwinell MR, Powell FL) FASEB Journal 20 March 1998;12(5) SCOPUS ID: 2-s2.0-33749219526 03/20/1998    
  • The role of D2-dopamine receptors in ventilatory acclimatization to chronic hypoxia in mice (Huey KA, Szewczak J, Dwinell MR, Juarez RA, Low MJ, Powell FL) FASEB Journal 20 March 1998;12(5) SCOPUS ID: 2-s2.0-23544469596 03/20/1998       2 Citations
  • Intracarotid dopamine infusion does not prevent acclimatization to hypoxia. (Janssen PL, Dwinell MR, Pizarro J, Bisgard GE) Respir Physiol 1998 Jan;111(1):33-43 PMID: 9496470 SCOPUS ID: 2-s2.0-0031963147 03/13/1998       13 Citations
  • Carotid body dopaminergic mechanisms are functional after acclimatization to hypoxia in goats. (Janssen PL, O'Halloran KD, Pizarro J, Dwinell MR, Bisgard GE) Respir Physiol 1998 Jan;111(1):25-32 PMID: 9496469 SCOPUS ID: 2-s2.0-0031963774 03/13/1998       22 Citations
  • Lack of long-term facilitation of ventilation after exposure to hypoxia in goats. (Dwinell MR, Janssen PL, Bisgard GE) Respir Physiol 1997 Apr;108(1):1-9 PMID: 9178372 SCOPUS ID: 2-s2.0-0030920213 04/01/1997       36 Citations
  • Effects of carotid body hypocapnia during ventilatory acclimatization to hypoxia. (Dwinell MR, Janssen PL, Pizarro J, Bisgard GE) J Appl Physiol (1985) 1997 Jan;82(1):118-24 PMID: 9029206 SCOPUS ID: 2-s2.0-0031019367 01/01/1997       15 Citations
  • Increased carotid body CO2 sensitivity after ventilatory acclimatization to hypoxia in goats (Dwinell MR, Janssen PL, Pizarro J, Bisgard GE) FASEB Journal 1996;10(3) SCOPUS ID: 2-s2.0-33749184060 12/01/1996    
  • The role of carotid body CO2 during ventilatory acclimatization to hypoxia in the goat. (Dwinell MR, Janssen PL, Pizarro J, Bisgard GE) Adv Exp Med Biol 1996;410:387-90 PMID: 9030330 SCOPUS ID: 2-s2.0-0030482048 01/01/1996       1 Citation
  • Effects of continuous intracarotid infusion of dopamine during long-term hypoxia in awake goats. (Janssen PL, Dwinell MR, Pizarro DJ, Bisgard GE) Adv Exp Med Biol 1996;410:383-6 PMID: 9030329 SCOPUS ID: 2-s2.0-0030477465 01/01/1996       2 Citations
  • Mitochondrial division, blood vessel dilation, and large intercellular space expansion of goat carotid body during hypoxia. (Xue D, Keith IM, Dwinell MR, Bisgard GE) Adv Exp Med Biol 1996;410:55-8 PMID: 9030276 SCOPUS ID: 2-s2.0-0030451660 01/01/1996       1 Citation
  • Recurrent laryngeal nerve activation by alpha 2 adrenergic agonists in goats. (Hedrick MS, Ryan ML, Bisgard GE) Respir Physiol 1995 Aug;101(2):129-37 PMID: 8570915 SCOPUS ID: 2-s2.0-0029143789 08/01/1995       16 Citations
  • Intracarotid substance P infusion inhibits ventilation in the goat. (Pizarro J, Ryan ML, Hedrick MS, Xue DH, Keith IM, Bisgard GE) Respir Physiol 1995 Jul;101(1):11-22 PMID: 8525117 SCOPUS ID: 2-s2.0-0029153142 07/01/1995       13 Citations
  • Effects of carotid body sympathetic denervation on ventilatory acclimatization to hypoxia in the goat. (Ryan ML, Hedrick MS, Pizarro J, Bisgard GE) Respir Physiol 1995 Feb;99(2):215-24 PMID: 7777704 SCOPUS ID: 2-s2.0-0028881635 02/01/1995       18 Citations
  • Modulation of respiratory rhythm by alpha 2-adrenoceptors in awake and anesthetized goats. (Hedrick MS, Ryan ML, Pizarro J, Bisgard GE) J Appl Physiol (1985) 1994 Aug;77(2):742-50 PMID: 8002523 SCOPUS ID: 2-s2.0-0027981310 08/01/1994       27 Citations
  • Substance P inhibits ventilation in the goat. (Bisgard GE, Pizarro J, Ryan M, Hedrick M) Adv Exp Med Biol 1994;360:277-9 PMID: 7532902 SCOPUS ID: 2-s2.0-0028154786 01/01/1994       1 Citation
  • Carotid body noradrenergic sensitivity in ventilatory acclimatization to hypoxia. (Ryan ML, Hedrick MS, Pizarro J, Bisgard GE) Respir Physiol 1993 Apr;92(1):77-90 PMID: 8390087 SCOPUS ID: 2-s2.0-0027469614 04/01/1993       25 Citations
  • Intracarotid norepinephrine infusions inhibit ventilation in goats. (Pizarro J, Warner MM, Ryan M, Mitchell GS, Bisgard GE) Respir Physiol 1992 Dec;90(3):299-310 PMID: 1480841 SCOPUS ID: 2-s2.0-0026465287 12/01/1992       27 Citations
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