| 5 | Phosphorylation of distal C-terminal residues promotes TRPV4 channel activation in response to arachidonic acid. (Parthasarathy A, Anishkin A, Xie Y, Drachuk K, Nishijma Y, Fang J, Koukouritaki SB, Wilcox DA, Zhang DX) J Biol Chem 2025 Mar;301(3):108260 1 Citation |
| 1 | The NmpRSTU multi-component signaling system of Myxococcus xanthus regulates expression of an oxygen utilization regulon. (McAllister CT, Ronk AM, Stenzel MJ, Kirby JR, Bretl DJ) J Bacteriol 2025 Feb 20;207(2):e0028024 |
| 1 | IQGAP1 promotes early B cell development, is essential for the development of marginal zone (MZ) B cells, and is critical for both T-dependent and T-independent antibody responses. (Lella RK, Malarkannan S) Cell Mol Life Sci 2024 Nov 25;81(1):462 1 Citation |
| 1 | Astrocytic glutamate transport is essential for the memory-enhancing effects of 17β-estradiol in ovariectomized mice. (Taxier LR, Pillerová M, Branyan TE, Sohrabji F, Frick KM) Horm Behav 2024 Sep;165:105618 2 Citations |
| 3 | Decreased Liver Kinase B1 Expression and Impaired Angiogenesis in a Murine Model of Bronchopulmonary Dysplasia. (Rana U, Joshi C, Whitney E, Afolayan A, Dowell J, Teng RJ, Konduri GG) Am J Respir Cell Mol Biol 2024 Oct;71(4):481-494 1 Citation |
| 1 | Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer. (Klomp JE, Diehl JN, Klomp JA, Edwards AC, Yang R, Morales AJ, Taylor KE, Drizyte-Miller K, Bryant KL, Schaefer A, Johnson JL, Huntsman EM, Yaron TM, Pierobon M, Baldelli E, Prevatte AW, Barker NK, Herring LE, Petricoin EF 3rd, Graves LM, Cantley LC, Cox AD, Der CJ, Stalnecker CA) Science 2024 Jun 07;384(6700):eadk0850 31 Citations |
| 4 | Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity. (Yang C, Isaeva E, Shimada S, Kurth T, Stumpf M, Zheleznova NN, Staruschenko A, Dash RK, Cowley AW Jr) Am J Physiol Renal Physiol 2024 Sep 01;327(3):F435-F449 |
| 2 | Studying the O-GlcNAcome of human placentas using banked tissue samples. (Luna S, Malard F, Pereckas M, Aoki M, Aoki K, Olivier-Van Stichelen S) Glycobiology 2024 Apr 10;34(4) 6 Citations |
| 3 | Multisite Phosphorylation Regulates GpsB Function in Cephalosporin Resistance of Enterococcus faecalis. (VanZeeland NE, Schultz KM, Klug CS, Kristich CJ) J Mol Biol 2023 Sep 15;435(18):168216 6 Citations |
| 2 | p38γ MAPK Inflammatory and Metabolic Signaling in Physiology and Disease. (Qi XM, Chen G) Cells 2023 Jun 21;12(13) 10 Citations |
| 3 | Conformational changes in the activation loop of a bacterial PASTA kinase. (Bluma MS, Schultz KM, Kristich CJ, Klug CS) Protein Sci 2023 Jul;32(7):e4697 3 Citations |
| 2 | Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance. (Gao X, Wu Y, Chick JM, Abbott A, Jiang B, Wang DJ, Comte-Walters S, Johnson RH, Oberholtzer N, Nishimura MI, Gygi SP, Mehta A, Guttridge DC, Ball L, Mehrotra S, Sicinski P, Yu XZ, Wang H) Cell Rep 2023 Apr 25;42(4):112314 4 Citations |
| 4 | Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control. (Ghosh AK, Su YP, Forman M, Keyes RF, Smith BC, Hu X, Ferrer M, Arav-Boger R) J Virol 2023 Apr 27;97(4):e0016023 2 Citations |
| 3 | OLA1 Phosphorylation Governs the Mitochondrial Bioenergetic Function of Pulmonary Vascular Cells. (Sidlowski P, Czerwinski A, Liu Y, Liu P, Teng RJ, Kumar S, Wells C, Pritchard K Jr, Konduri GG, Afolayan AJ) Am J Respir Cell Mol Biol 2023 Apr;68(4):395-405 4 Citations |
| 1 | JAK: Not Just Another Kinase. (Agashe RP, Lippman SM, Kurzrock R) Mol Cancer Ther 2022 Dec 02;21(12):1757-1764 91 Citations |
| 1 | G protein-coupled receptor kinase phosphorylation of distal C-tail sites specifies βarrestin1-mediated signaling by chemokine receptor CXCR4. (Zhuo Y, Crecelius JM, Marchese A) J Biol Chem 2022 Sep;298(9):102351 11 Citations |
| 1 | Role of Src kinase in regulating protein kinase C mediated phosphorylation of TRPV1. (Robilotto GL, Mohapatra DP, Shepherd AJ, Mickle AD) Eur J Pain 2022 Oct;26(9):1967-1978 12 Citations |
| 5 | NADPH oxidase 4 contributes to TRPV4-mediated endothelium-dependent vasodilation in human arterioles by regulating protein phosphorylation of TRPV4 channels. (Xie Y, Nishijima Y, Zinkevich NS, Korishettar A, Fang J, Mathison AJ, Zimmermann MT, Wilcox DA, Gutterman DD, Shen Y, Zhang DX) Basic Res Cardiol 2022 Apr 25;117(1):24 11 Citations |
| 1 | Phosphorylated MED1 links transcription recycling and cancer growth. (Chen Z, Ye Z, Soccio RE, Nakadai T, Hankey W, Zhao Y, Huang F, Yuan F, Wang H, Cui Z, Sunkel B, Wu D, Dzeng RK, Thomas-Ahner JM, Huang THM, Clinton SK, Huang J, Lazar MA, Jin VX, Roeder RG, Wang Q) Nucleic Acids Res 2022 May 06;50(8):4450-4463 11 Citations |
| 1 | Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans. (Oslin K, Reho JJ, Lu Y, Khanal S, Kenchegowda D, Prior SJ, Fisher SA) Am J Physiol Regul Integr Comp Physiol 2022 Apr 01;322(4):R281-R291 4 Citations |
| 2 | IreK-Mediated, Cell Wall-Protective Phosphorylation in Enterococcus faecalis. (Iannetta AA, Minton NE, Uitenbroek AA, Little JL, Stanton CR, Kristich CJ, Hicks LM) J Proteome Res 2021 Nov 05;20(11):5131-5144 15 Citations |
| 1 | Phosphorylation of Pal2 by the protein kinases Kin1 and Kin2 modulates HAC1 mRNA splicing in the unfolded protein response in yeast. (Ghosh C, Uppala JK, Sathe L, Hammond CI, Anshu A, Pokkuluri PR, Turk BE, Dey M) Sci Signal 2021 May 25;14(684) 7 Citations |
| 3 | Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate. (Miller JJ, Bohnsack RN, Olson LJ, Ishihara M, Aoki K, Tiemeyer M, Dahms NM) Sci Rep 2021 Apr 15;11(1):8213 3 Citations |
| 1 | Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility. (Lynch TL 4th, Kumar M, McNamara JW, Kuster DWD, Sivaguru M, Singh RR, Previs MJ, Lee KH, Kuffel G, Zilliox MJ, Lin BL, Ma W, Gibson AM, Blaxall BC, Nieman ML, Lorenz JN, Leichter DM, Leary OP, Janssen PML, de Tombe PP, Gilbert RJ, Craig R, Irving T, Warshaw DM, Sadayappan S) J Mol Cell Cardiol 2021 Jul;156:33-44 21 Citations |
| 1 | Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis. (Kasikara C, Schilperoort M, Gerlach B, Xue C, Wang X, Zheng Z, Kuriakose G, Dorweiler B, Zhang H, Fredman G, Saleheen D, Reilly MP, Tabas I) J Clin Invest 2021 Apr 15;131(8) 40 Citations |
| 1 | Follicular Lymphoma-associated BTK Mutations are Inactivating Resulting in Augmented AKT Activation. (Hu N, Wang F, Sun T, Xu Z, Zhang J, Bernard D, Xu S, Wang S, Kaminski M, Devata S, Phillips T, Malek SN) Clin Cancer Res 2021 Apr 15;27(8):2301-2313 20 Citations |
| 1 | Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility. (Wang Y, Shi Q, Li M, Zhao M, Reddy Gopireddy R, Teoh JP, Xu B, Zhu C, Ireton KE, Srinivasan S, Chen S, Gasser PJ, Bossuyt J, Hell JW, Bers DM, Xiang YK) Circ Res 2021 Jan 22;128(2):246-261 53 Citations |
| 1 | Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses. (Kennedy RB, Haralambieva IH, Ovsyannikova IG, Voigt EA, Larrabee BR, Schaid DJ, Zimmermann MT, Oberg AL, Poland GA) Front Immunol 2020;11:567348 21 Citations |
| 1 | SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma. (Young TL, Whisenhunt KN, Jin J, LaMartina SM, Martin SM, Souma T, Limviphuvadh V, Suri F, Souzeau E, Zhang X, Dan Y, Anagnos E, Carmona S, Jody NM, Stangel N, Higuchi EC, Huang SJ, Siggs OM, Simões MJ, Lawson BM, Martin JS, Elahi E, Narooie-Nejad M, Motlagh BF, Quaggin SE, Potter HD, Silva ED, Craig JE, Egas C, Maroofian R, Maurer-Stroh S, Bradfield YS, Tompson SW) Invest Ophthalmol Vis Sci 2020 Oct 01;61(12):6 38 Citations |
| 2 | Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition. (Roy S, Kapoor A, Zhu F, Mukhopadhyay R, Ghosh AK, Lee H, Mazzone J, Posner GH, Arav-Boger R) J Biol Chem 2020 Oct 30;295(44):15013-15028 15 Citations |
| 1 | Growth Inhibitory Signaling of the Raf/MEK/ERK Pathway. (Wu PK, Becker A, Park JI) Int J Mol Sci 2020 Jul 30;21(15) 71 Citations |
| 1 | Age-Related Memory Impairment Is Associated with Increased zif268 Protein Accumulation and Decreased Rpt6 Phosphorylation. (Trask S, Dulka BN, Helmstetter FJ) Int J Mol Sci 2020 Jul 28;21(15) 10 Citations |
| 1 | Cyclin D-CDK4/6 functions in cancer. (Gao X, Leone GW, Wang H) Adv Cancer Res 2020;148:147-169 169 Citations |
| 4 | p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis. (Wang F, Qi XM, Wertz R, Mortensen M, Hagen C, Evans J, Sheinin Y, James M, Liu P, Tsai S, Thomas J, Mackinnon A, Dwinell M, Myers CR, Bartrons Bach R, Fu L, Chen G) Cancer Res 2020 Aug 15;80(16):3251-3264 62 Citations |
| 1 | RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival. (DeHelian D, Gupta S, Wu J, Thorsheim C, Estevez B, Cooper M, Litts K, Lee-Sundlov MM, Hoffmeister KM, Poncz M, Ma P, Brass LF) Blood 2020 Oct 08;136(15):1773-1782 21 Citations |
| 5 | Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity. (Deng G, Morselli LL, Wagner VA, Balapattabi K, Sapouckey SA, Knudtson KL, Rahmouni K, Cui H, Sigmund CD, Kwitek AE, Grobe JL) Hypertension 2020 Aug;76(2):589-597 25 Citations |
| 1 | Endogenous miR-204 Protects the Kidney against Chronic Injury in Hypertension and Diabetes. (Cheng Y, Wang D, Wang F, Liu J, Huang B, Baker MA, Yin J, Wu R, Liu X, Regner KR, Usa K, Liu Y, Zhang C, Dong L, Geurts AM, Wang N, Miller SS, He Y, Liang M) J Am Soc Nephrol 2020 Jul;31(7):1539-1554 77 Citations |
| 1 | SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in AppNL-G-F/NL-G-F Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling. (Izumi H, Kawahata I, Shinoda Y, Helmstetter FJ, Fukunaga K) Int J Mol Sci 2020 May 28;21(11) 10 Citations |
| 1 | NOX4/H2O2/mTORC1 Pathway in Salt-Induced Hypertension and Kidney Injury. (Kumar V, Kurth T, Zheleznova NN, Yang C, Cowley AW Jr) Hypertension 2020 Jul;76(1):133-143 31 Citations |
| 1 | Ectopic PD-L1 expression in JAK2 (V617F) myeloproliferative neoplasm patients is mediated via increased activation of STAT3 and STAT5. (Guru SA, Sumi MP, Mir R, Waza AA, Bhat MA, Zuberi M, Lali P, Saxena A) Hum Cell 2020 Oct;33(4):1099-1111 14 Citations |
| 1 | PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy. (Oeing CU, Nakamura T, Pan S, Mishra S, Dunkerly-Eyring BL, Kokkonen-Simon KM, Lin BL, Chen A, Zhu G, Bedja D, Lee DI, Kass DA, Ranek MJ) Circ Res 2020 Jul 31;127(4):522-533 40 Citations |
| 1 | Age-related memory deficits are associated with changes in protein degradation in brain regions critical for trace fear conditioning. (Dulka BN, Pullins SE, Cullen PK, Moyer JR Jr, Helmstetter FJ) Neurobiol Aging 2020 Jul;91:160-166 16 Citations |
| 2 | Network mechanisms and dysfunction within an integrated computational model of progression through mitosis in the human cell cycle. (Terhune SS, Jung Y, Cataldo KM, Dash RK) PLoS Comput Biol 2020 Apr;16(4):e1007733 7 Citations |
| 3 | AMP-Kinase Dysfunction Alters Notch Ligands to Impair Angiogenesis in Neonatal Pulmonary Hypertension. (Rana U, Callan E, Entringer B, Michalkiewicz T, Joshi A, Parchur AK, Teng RJ, Konduri GG) Am J Respir Cell Mol Biol 2020 Jun;62(6):719-731 27 Citations |
| 1 | Dynamic CRMP2 Regulation of CaV2.2 in the Prefrontal Cortex Contributes to the Reinstatement of Cocaine Seeking. (Buchta WC, Moutal A, Hines B, Garcia-Keller C, Smith ACW, Kalivas P, Khanna R, Riegel AC) Mol Neurobiol 2020 Jan;57(1):346-357 10 Citations |
| 1 | β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition. (Cui Y, Jiang L, Yu R, Shao Y, Mei L, Tao Y) J Ethnopharmacol 2019 Oct 28;243:112096 41 Citations |
| 1 | Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. (Bowen C, Ostrowski MC, Leone G, Gelmann EP) Cancer Res 2019 Aug 15;79(16):4124-4134 29 Citations |
| 3 | Modeling post-translational modifications and cancer-associated mutations that impact the heterochromatin protein 1α-importin α heterodimers. (Zimmermann MT, Williams MM, Klee EW, Lomberk GA, Urrutia R) Proteins 2019 Nov;87(11):904-916 4 Citations |
| 4 | Aurora kinase B-phosphorylated HP1α functions in chromosomal instability. (Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA) Cell Cycle 2019 Jun;18(12):1407-1421 9 Citations |
| 1 | Potency Analysis of Mesenchymal Stromal Cells Using a Phospho-STAT Matrix Loop Analytical Approach. (Chinnadurai R, Rajakumar A, Schneider AJ, Bushman WA, Hematti P, Galipeau J) Stem Cells 2019 Aug;37(8):1119-1125 23 Citations |
| 1 | Upstream signaling events leading to elevated production of pro-survival nitric oxide in photodynamically-challenged glioblastoma cells. (Fahey JM, Korytowski W, Girotti AW) Free Radic Biol Med 2019 Jun;137:37-45 31 Citations |
| 1 | Progesterone Receptor Attenuates STAT1-Mediated IFN Signaling in Breast Cancer. (Goodman ML, Trinca GM, Walter KR, Papachristou EK, D'Santos CS, Li T, Liu Q, Lai Z, Chalise P, Madan R, Fan F, Markiewicz MA, Jin VX, Carroll JS, Hagan CR) J Immunol 2019 May 15;202(10):3076-3086 38 Citations |
| 1 | Reciprocal Regulation of PASTA Kinase Signaling by Differential Modification. (Labbe BD, Hall CL, Kellogg SL, Chen Y, Koehn O, Pickrum AM, Mirza SP, Kristich CJ) J Bacteriol 2019 May 15;201(10) 12 Citations |
| 1 | Decorin antagonizes corneal fibroblast migration via caveolae-mediated endocytosis of epidermal growth factor receptor. (Mohan RR, Tripathi R, Sharma A, Sinha PR, Giuliano EA, Hesemann NP, Chaurasia SS) Exp Eye Res 2019 Mar;180:200-207 29 Citations |
| 1 | Identification and targeting of novel CDK9 complexes in acute myeloid leukemia. (Beauchamp EM, Abedin SM, Radecki SG, Fischietti M, Arslan AD, Blyth GT, Yang A, Lantz C, Nelson A, Goo YA, Akpan I, Eklund EA, Frankfurt O, Fish EN, Thomas PM, Altman JK, Platanias LC) Blood 2019 Mar 14;133(11):1171-1185 36 Citations |
| 2 | Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. (Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA Jr) Cell Mol Gastroenterol Hepatol 2019;7(1):55-71 30 Citations |
| 4 | Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance. (Zemanovic S, Ivanov MV, Ivanova LV, Bhatnagar A, Michalkiewicz T, Teng RJ, Kumar S, Rathore R, Pritchard KA Jr, Konduri GG, Afolayan AJ) Cell Rep 2018 Nov 27;25(9):2605-2616.e7 51 Citations |
| 1 | Kif17 phosphorylation regulates photoreceptor outer segment turnover. (Lewis TR, Kundinger SR, Link BA, Insinna C, Besharse JC) BMC Cell Biol 2018 Nov 20;19(1):25 28 Citations |
| 3 | Suppressor mutations reveal an NtrC-like response regulator, NmpR, for modulation of Type-IV Pili-dependent motility in Myxococcus xanthus. (Bretl DJ, Ladd KM, Atkinson SN, Müller S, Kirby JR) PLoS Genet 2018 Oct;14(10):e1007714 6 Citations |
| 1 | Biased antagonism of CXCR4 avoids antagonist tolerance. (Hitchinson B, Eby JM, Gao X, Guite-Vinet F, Ziarek JJ, Abdelkarim H, Lee Y, Okamoto Y, Shikano S, Majetschak M, Heveker N, Volkman BF, Tarasova NI, Gaponenko V) Sci Signal 2018 Oct 16;11(552) 36 Citations |
| 1 | Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma. (Ananieva EA, Bostic JN, Torres AA, Glanz HR, McNitt SM, Brenner MK, Boyer MP, Addington AK, Hutson SM) Br J Cancer 2018 Oct;119(8):1009-1017 16 Citations |
| 3 | Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway. (Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R) Sci Rep 2018 Oct 10;8(1):15077 5 Citations |
| 1 | A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. (Sadler JBA, Wenzel DM, Strohacker LK, Guindo-Martínez M, Alam SL, Mercader JM, Torrents D, Ullman KS, Sundquist WI, Martin-Serrano J) Proc Natl Acad Sci U S A 2018 Sep 18;115(38):E8900-E8908 52 Citations |
| 1 | Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) Cell Physiol Biochem 2018;49(2):512-529 19 Citations |
| 1 | FoxO1 and FoxA1/2 form a complex on DNA and cooperate to open chromatin at insulin-regulated genes. (Schill D, Nord J, Cirillo LA) Biochem Cell Biol 2019 Apr;97(2):118-129 9 Citations |
| 1 | Phosphorylation of translation initiation factor eIF2α at Ser51 depends on site- and context-specific information. (Uppala JK, Ghosh C, Sathe L, Dey M) FEBS Lett 2018 Sep;592(18):3116-3125 9 Citations |
| 1 | Temperature-sensitive sarcomeric protein post-translational modifications revealed by top-down proteomics. (Cai W, Hite ZL, Lyu B, Wu Z, Lin Z, Gregorich ZR, Messer AE, McIlwain SJ, Marston SB, Kohmoto T, Ge Y) J Mol Cell Cardiol 2018 Sep;122:11-22 18 Citations |
| 2 | Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium. (Hsu AH, Lum MA, Shim KS, Frederick PJ, Morrison CD, Chen B, Lele SM, Sheinin YM, Daikoku T, Dey SK, Leone G, Black AR, Black JD) Cell Rep 2018 Jul 17;24(3):655-669 40 Citations |
| 1 | Endocytosis is required for CXC chemokine receptor type 4 (CXCR4)-mediated Akt activation and antiapoptotic signaling. (English EJ, Mahn SA, Marchese A) J Biol Chem 2018 Jul 20;293(29):11470-11480 37 Citations |
| 2 | GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells. (Park SK, Herrnreiter A, Pfister SL, Gauthier KM, Falck BA, Falck JR, Campbell WB) J Biol Chem 2018 Jul 06;293(27):10675-10691 58 Citations |
| 2 | Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin. (Murthy T, Bluemn T, Gupta AK, Reimer M Jr, Rao S, Pillai MM, Minella AC) J Biol Chem 2018 Jun 29;293(26):10220-10234 14 Citations |
| 1 | Convergence of PASTA Kinase and Two-Component Signaling in Response to Cell Wall Stress in Enterococcus faecalis. (Kellogg SL, Kristich CJ) J Bacteriol 2018 Jun 15;200(12) 33 Citations |
| 3 | Transient receptor potential vanilloid 4 (TRPV4) activation by arachidonic acid requires protein kinase A-mediated phosphorylation. (Cao S, Anishkin A, Zinkevich NS, Nishijima Y, Korishettar A, Wang Z, Fang J, Wilcox DA, Zhang DX) J Biol Chem 2018 Apr 06;293(14):5307-5322 60 Citations |
| 1 | P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. (Dou C, Liu Z, Tu K, Zhang H, Chen C, Yaqoob U, Wang Y, Wen J, van Deursen J, Sicard D, Tschumperlin D, Zou H, Huang WC, Urrutia R, Shah VH, Kang N) Gastroenterology 2018 Jun;154(8):2209-2221.e14 193 Citations |
| 1 | Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide-Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells. (Oleson BJ, Naatz A, Proudfoot SC, Yeo CT, Corbett JA) Diabetes 2018 May;67(5):898-910 9 Citations |
| 1 | Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA) Nat Commun 2018 Feb 02;9(1):476 42 Citations |
| 1 | Nogo-B receptor increases the resistance of estrogen receptor positive breast cancer to paclitaxel. (Jin Y, Hu W, Liu T, Rana U, Aguilera-Barrantes I, Kong A, Kumar SN, Wang B, Gao P, Wang X, Duan Y, Shi A, Song D, Yang M, Li S, Han B, Zhao G, Fan Z, Miao QR) Cancer Lett 2018 Apr 10;419:233-244 16 Citations |
| 1 | Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. (Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, Liu J, Wu Y, Jin VX, Dai X, Guo J, Liu J, Jiang S, Li J, Asara JM, Brown M, Hung MC, Wei W) Mol Cell 2018 Jan 18;69(2):279-291.e5 155 Citations |
| 1 | Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects. (Ferdaus MZ, Miller LN, Agbor LN, Saritas T, Singer JD, Sigmund CD, McCormick JA) JCI Insight 2017 Dec 21;2(24) 48 Citations |
| 1 | Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis. (Noh K, Mangala LS, Han HD, Zhang N, Pradeep S, Wu SY, Ma S, Mora E, Rupaimoole R, Jiang D, Wen Y, Shahzad MMK, Lyons Y, Cho M, Hu W, Nagaraja AS, Haemmerle M, Mak CSL, Chen X, Gharpure KM, Deng H, Xiong W, Kingsley CV, Liu J, Jennings N, Birrer MJ, Bouchard RR, Lopez-Berestein G, Coleman RL, An Z, Sood AK) Cell Rep 2017 Dec 05;21(10):2785-2795 37 Citations |
| 1 | The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis. (Branchford BR, Stalker TJ, Law L, Acevedo G, Sather S, Brzezinski C, Wilson KM, Minson K, Lee-Sherick AB, Davizon-Castillo P, Ng C, Zhang W, Neeves KB, Lentz SR, Wang X, Frye SV, Shelton Earp H 3rd, DeRyckere D, Brass LF, Graham DK, Di Paola JA) J Thromb Haemost 2018 Feb;16(2):352-363 26 Citations |
| 1 | Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4. (Olp MD, Zhu N, Smith BC) Biochemistry 2017 Oct 17;56(41):5485-5495 21 Citations |
| 2 | Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4-mediated necrotizing enterocolitis in a mouse model. (Fawley J, Cuna A, Menden HL, McElroy S, Umar S, Welak SR, Gourlay DM, Li X, Sampath V) Pediatr Res 2018 Jan;83(1-1):164-174 31 Citations |
| 1 | Growth- and Stress-Induced PASTA Kinase Phosphorylation in Enterococcus faecalis. (Labbe BD, Kristich CJ) J Bacteriol 2017 Nov 01;199(21) 30 Citations |
| 1 | Minocycline modulates NFκB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells. (Guerra AD, Rose WE, Hematti P, Kao WJ) Stem Cell Res Ther 2017 Jul 21;8(1):171 16 Citations |
| 3 | Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling. (Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW) Cold Spring Harb Mol Case Stud 2017 Jul;3(4) 8 Citations |
| 1 | Steady-State Levels of Phosphorylated Mitogen-Activated Protein Kinase Kinase 1/2 Determined by Mortalin/HSPA9 and Protein Phosphatase 1 Alpha in KRAS and BRAF Tumor Cells. (Wu PK, Hong SK, Park JI) Mol Cell Biol 2017 Sep 15;37(18) 23 Citations |
| 1 | Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling. (Liu Y, Baumgardt SL, Fang J, Shi Y, Qiao S, Bosnjak ZJ, Vásquez-Vivar J, Xia Z, Warltier DC, Kersten JR, Ge ZD) Sci Rep 2017 Jun 08;7(1):3093 15 Citations |
| 1 | Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands. (Shin K, Chapman NA, Sarker M, Kenward C, Huang SK, Weatherbee-Martin N, Pandey A, Dupré DJ, Rainey JK) Biochim Biophys Acta Gen Subj 2017 Aug;1861(8):1901-1912 31 Citations |
| 3 | Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe. (Mathison A, Salmonson A, Missfeldt M, Bintz J, Williams M, Kossak S, Nair A, de Assuncao TM, Christensen T, Buttar N, Iovanna J, Huebert R, Lomberk G) Mol Cancer Res 2017 Aug;15(8):984-997 17 Citations |
| 1 | Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. (Gregorich ZR, Cai W, Lin Z, Chen AJ, Peng Y, Kohmoto T, Ge Y) J Mol Cell Cardiol 2017 Jun;107:13-21 30 Citations |
| 1 | Proteomic Screen for Cellular Targets of the Vaccinia Virus F10 Protein Kinase Reveals that Phosphorylation of mDia Regulates Stress Fiber Formation. (Greseth MD, Carter DC, Terhune SS, Traktman P) Mol Cell Proteomics 2017 Apr;16(4 suppl 1):S124-S143 9 Citations |
| 1 | The Pseudomonas aeruginosa Exoenzyme Y: A Promiscuous Nucleotidyl Cyclase Edema Factor and Virulence Determinant. (Morrow KA, Frank DW, Balczon R, Stevens T) Handb Exp Pharmacol 2017;238:67-85 24 Citations |
| 1 | Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease. (Dean DC 3rd, Hurley SA, Kecskemeti SR, O'Grady JP, Canda C, Davenport-Sis NJ, Carlsson CM, Zetterberg H, Blennow K, Asthana S, Sager MA, Johnson SC, Alexander AL, Bendlin BB) JAMA Neurol 2017 Jan 01;74(1):41-49 190 Citations |
| 2 | Role of Twist1 Phosphorylation in Angiogenesis and Pulmonary Fibrosis. (Mammoto T, Jiang A, Jiang E, Mammoto A) Am J Respir Cell Mol Biol 2016 Nov;55(5):633-644 42 Citations |
| 1 | Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival. (Abhishek K, Sardar AH, Das S, Kumar A, Ghosh AK, Singh R, Saini S, Mandal A, Verma S, Kumar A, Purkait B, Dikhit MR, Das P) Mol Cell Biol 2017 Jan 01;37(1) 19 Citations |
| 1 | E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. (Swartz KL, Wood SN, Murthy T, Ramirez O, Qin G, Pillai MM, Rao S, Minella AC) Mol Cell Biol 2017 Jan 01;37(1) 24 Citations |
| 1 | β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4. (Alekhina O, Marchese A) J Biol Chem 2016 Dec 09;291(50):26083-26097 30 Citations |
| 4 | Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development. (Fu G, Yu M, Chen Y, Zheng Y, Zhu W, Newman DK, Wang D, Wen R) Eur J Immunol 2017 Jan;47(1):74-83 8 Citations |
| 1 | Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B. (Wilson JM, Prokop JW, Lorimer E, Ntantie E, Williams CL) J Mol Biol 2016 Dec 04;428(24 Pt B):4929-4945 26 Citations |
| 1 | Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 toward Phosphorylated ERKs. (Talipov MR, Nayak J, Lepley M, Bongard RD, Sem DS, Ramchandran R, Rathore R) Biochemistry 2016 Nov 08;55(44):6187-6195 7 Citations |
| 1 | MICAL1 controls cell invasive phenotype via regulating oxidative stress in breast cancer cells. (Deng W, Wang Y, Gu L, Duan B, Cui J, Zhang Y, Chen Y, Sun S, Dong J, Du J) BMC Cancer 2016 Jul 18;16:489 54 Citations |
| 1 | Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases. (Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, Benjamin IJ, Keyse SM, Cuenda A, Dinkova-Kostova AT) Mol Cell Biol 2016 Sep 15;36(18):2403-17 61 Citations |
| 2 | Prolonged esophageal acid exposures induce synaptic downscaling of cortical membrane AMPA receptor subunits in rats. (Banerjee B, Medda BK, Zhang J, Tuchscherer V, Babygirija R, Kannampalli P, Sengupta JN, Shaker R) Neurogastroenterol Motil 2016 Sep;28(9):1356-69 1 Citation |
| 1 | Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells. (Aouar B, Kovarova D, Letard S, Font-Haro A, Florentin J, Weber J, Durantel D, Chaperot L, Plumas J, Trejbalova K, Hejnar J, Nunès JA, Olive D, Dubreuil P, Hirsch I, Stranska R) PLoS One 2016;11(6):e0156063 29 Citations |
| 1 | PIAS1 Promotes Lymphomagenesis through MYC Upregulation. (Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP) Cell Rep 2016 Jun 07;15(10):2266-2278 40 Citations |
| 1 | Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. (Chapleau MW, Rotella DL, Reho JJ, Rahmouni K, Stauss HM) Am J Physiol Heart Circ Physiol 2016 Jul 01;311(1):H276-85 45 Citations |
| 3 | Nitric Oxide Suppresses β-Cell Apoptosis by Inhibiting the DNA Damage Response. (Oleson BJ, Broniowska KA, Naatz A, Hogg N, Tarakanova VL, Corbett JA) Mol Cell Biol 2016 Aug 01;36(15):2067-77 40 Citations |
| 1 | Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation. (Chugh S, Meza J, Sheinin YM, Ponnusamy MP, Batra SK) Br J Cancer 2016 Jun 14;114(12):1376-86 44 Citations |
| 1 | HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. (Su KH, Cao J, Tang Z, Dai S, He Y, Sampson SB, Benjamin IJ, Dai C) Nat Cell Biol 2016 May;18(5):527-39 69 Citations |
| 1 | Ac-SDKP suppresses TNF-α-induced ICAM-1 expression in endothelial cells via inhibition of IκB kinase and NF-κB activation. (Zhu L, Yang XP, Janic B, Rhaleb NE, Harding P, Nakagawa P, Peterson EL, Carretero OA) Am J Physiol Heart Circ Physiol 2016 May 01;310(9):H1176-83 25 Citations |
| 1 | Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes. (Yalley A, Schill D, Hatta M, Johnson N, Cirillo LA) J Biol Chem 2016 Apr 15;291(16):8848-61 23 Citations |
| 1 | The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation. (Lasek AL, McPherson BM, Trueman NG, Burkard ME) PLoS One 2016;11(2):e0150225 12 Citations |
| 1 | Functional Dissection of the CroRS Two-Component System Required for Resistance to Cell Wall Stressors in Enterococcus faecalis. (Kellogg SL, Kristich CJ) J Bacteriol 2016 Apr;198(8):1326-36 30 Citations |
| 1 | ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis. (Lim RR, Tan A, Liu YC, Barathi VA, Mohan RR, Mehta JS, Chaurasia SS) Sci Rep 2016 Feb 11;6:20841 45 Citations |
| 1 | CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval. (Jarome TJ, Ferrara NC, Kwapis JL, Helmstetter FJ) Neurobiol Learn Mem 2016 Feb;128:103-9 100 Citations |
| 1 | FGFR and PTEN signaling interact during lens development to regulate cell survival. (Chaffee BR, Hoang TV, Leonard MR, Bruney DG, Wagner BD, Dowd JR, Leone G, Ostrowski MC, Robinson ML) Dev Biol 2016 Feb 15;410(2):150-163 24 Citations |
| 1 | Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice. (Baumgardt SL, Paterson M, Leucker TM, Fang J, Zhang DX, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD) Circ Heart Fail 2016 Jan;9(1):e002424 53 Citations |
| 3 | Nogo-B Receptor Modulates Pulmonary Artery Smooth Muscle Cell Function in Developing Lungs. (Tadokoro KS, Rana U, Jing X, Konduri GG, Miao QR, Teng RJ) Am J Respir Cell Mol Biol 2016 Jun;54(6):892-900 11 Citations |
| 1 | Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress. (Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD) Am J Physiol Heart Circ Physiol 2016 Jan 01;310(1):H39-48 50 Citations |
| 1 | Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cells. (Elrick MM, Samson WK, Corbett JA, Salvatori AS, Stein LM, Kolar GR, Naatz A, Yosten GL) Am J Physiol Regul Integr Comp Physiol 2016 Jan 15;310(2):R143-55 39 Citations |
| 1 | Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation. (Papadakis KA, Krempski J, Svingen P, Xiong Y, Sarmento OF, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Gastrointest Liver Physiol 2015 Dec 01;309(11):G900-9 21 Citations |
| 1 | Effect of Rho-kinase Inhibitor, Y27632, on Porcine Corneal Endothelial Cell Culture, Inflammation and Immune Regulation. (Lee W, Miyagawa Y, Long C, Zhang M, Cooper DK, Hara H) Ocul Immunol Inflamm 2016 Oct;24(5):579-93 12 Citations |
| 1 | Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas. (Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf EA, Egleston BL, Andrake MD, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH) Gastroenterology 2015 Dec;149(7):1872-1883.e9 29 Citations |
| 1 | Antagonistic Relationship between Human Cytomegalovirus pUL27 and pUL97 Activities during Infection. (Bigley TM, Reitsma JM, Terhune SS) J Virol 2015 Oct;89(20):10230-46 17 Citations |
| 1 | β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells. (Wilson JM, Lorimer E, Tyburski MD, Williams CL) Cancer Biol Ther 2015;16(9):1364-74 46 Citations |
| 1 | Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. (Jiang J, Burgon PG, Wakimoto H, Onoue K, Gorham JM, O'Meara CC, Fomovsky G, McConnell BK, Lee RT, Seidman JG, Seidman CE) Proc Natl Acad Sci U S A 2015 Jul 21;112(29):9046-51 43 Citations |
| 2 | Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. (Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A) Am J Respir Cell Mol Biol 2016 Jan;54(1):103-13 27 Citations |
| 1 | Neurogranin regulates CaM dynamics at dendritic spines. (Petersen A, Gerges NZ) Sci Rep 2015 Jun 18;5:11135 50 Citations |
| 3 | Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER). (Ma S, Yin N, Qi X, Pfister SL, Zhang MJ, Ma R, Chen G) Oncotarget 2015 May 30;6(15):13320-33 16 Citations |
| 1 | Regulation of GPCR Trafficking by Ubiquitin. (Kennedy JE, Marchese A) Prog Mol Biol Transl Sci 2015;132:15-38 47 Citations |
| 4 | The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage. (Leonard PH, Grzenda A, Mathison A, Morbeck DE, Fredrickson JR, de Assuncao TM, Christensen T, Salisbury J, Calvo E, Iovanna J, Coddington CC, Urrutia R, Lomberk G) BMC Dev Biol 2015 May 29;15:23 6 Citations |
| 1 | ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins. (Caballe A, Wenzel DM, Agromayor M, Alam SL, Skalicky JJ, Kloc M, Carlton JG, Labrador L, Sundquist WI, Martin-Serrano J) Elife 2015 May 26;4:e06547 76 Citations |
| 1 | A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome. (Lee EE, Ma J, Sacharidou A, Mi W, Salato VK, Nguyen N, Jiang Y, Pascual JM, North PE, Shaul PW, Mettlen M, Wang RC) Mol Cell 2015 Jun 04;58(5):845-53 119 Citations |
| 1 | NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair. (Bone KM, Wang P, Wu F, Wu C, Li L, Bacani JT, Andrew SE, Lai R) Blood Cancer J 2015 May 15;5(5):e311 10 Citations |
| 1 | STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma. (Wu C, Molavi O, Zhang H, Gupta N, Alshareef A, Bone KM, Gopal K, Wu F, Lewis JT, Douglas DN, Kneteman NM, Lai R) Blood 2015 Jul 16;126(3):336-45 28 Citations |
| 1 | Inhibition of human cytomegalovirus replication by artemisinins: effects mediated through cell cycle modulation. (Roy S, He R, Kapoor A, Forman M, Mazzone JR, Posner GH, Arav-Boger R) Antimicrob Agents Chemother 2015 Jul;59(7):3870-9 33 Citations |
| 1 | Alcohol inhibits osteopontin-dependent transforming growth factor-β1 expression in human mesenchymal stem cells. (Driver J, Weber CE, Callaci JJ, Kothari AN, Zapf MA, Roper PM, Borys D, Franzen CA, Gupta GN, Wai PY, Zhang J, Denning MF, Kuo PC, Mi Z) J Biol Chem 2015 Apr 17;290(16):9959-73 27 Citations |
| 1 | Active ERK2 is sufficient to mediate growth arrest and differentiation signaling. (Wu PK, Hong SK, Yoon SH, Park JI) FEBS J 2015 Mar;282(6):1017-30 18 Citations |
| 1 | Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells. (Menden H, Welak S, Cossette S, Ramchandran R, Sampath V) J Biol Chem 2015 Feb 27;290(9):5449-61 73 Citations |
| 1 | Unmethylated CpG motifs in the L. donovani DNA regulate TLR9-dependent delay of programmed cell death in macrophages. (Das S, Ghosh AK, Singh S, Saha B, Ganguly A, Das P) J Leukoc Biol 2015 Feb;97(2):363-78 15 Citations |
| 2 | Anti inflammatory and anti angiogenic effect of black raspberry extract on human esophageal and intestinal microvascular endothelial cells. (Medda R, Lyros O, Schmidt JL, Jovanovic N, Nie L, Link BJ, Otterson MF, Stoner GD, Shaker R, Rafiee P) Microvasc Res 2015 Jan;97:167-80 64 Citations |
| 1 | Enkephalin is essential for the molecular and behavioral expression of cocaine sensitization. (Mongi-Bragato B, Zamponi E, García-Keller C, Assis MA, Virgolini MB, Mascó DH, Zimmer A, Cancela LM) Addict Biol 2016 Mar;21(2):326-38 18 Citations |
| 1 | Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. (Milner JD, Vogel TP, Forbes L, Ma CA, Stray-Pedersen A, Niemela JE, Lyons JJ, Engelhardt KR, Zhang Y, Topcagic N, Roberson ED, Matthews H, Verbsky JW, Dasu T, Vargas-Hernandez A, Varghese N, McClain KL, Karam LB, Nahmod K, Makedonas G, Mace EM, Sorte HS, Perminow G, Rao VK, O'Connell MP, Price S, Su HC, Butrick M, McElwee J, Hughes JD, Willet J, Swan D, Xu Y, Santibanez-Koref M, Slowik V, Dinwiddie DL, Ciaccio CE, Saunders CJ, Septer S, Kingsmore SF, White AJ, Cant AJ, Hambleton S, Cooper MA) Blood 2015 Jan 22;125(4):591-9 474 Citations |
| 1 | Thymidine phosphorylase participates in platelet signaling and promotes thrombosis. (Li W, Gigante A, Perez-Perez MJ, Yue H, Hirano M, McIntyre TM, Silverstein RL) Circ Res 2014 Dec 05;115(12):997-1006 42 Citations |
| 2 | IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation. (Garcia MN, Grasso D, Lopez-Millan MB, Hamidi T, Loncle C, Tomasini R, Lomberk G, Porteu F, Urrutia R, Iovanna JL) J Clin Invest 2014 Nov;124(11):4709-22 41 Citations |
| 1 | PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation. (Meares GP, Liu Y, Rajbhandari R, Qin H, Nozell SE, Mobley JA, Corbett JA, Benveniste EN) Mol Cell Biol 2014 Oct;34(20):3911-25 189 Citations |
| 1 | Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. (Coaxum SD, Blanton MG, Joyner A, Akter T, Bell PD, Luttrell LM, Raymond JR Sr, Lee MH, Blichmann PA, Garnovskaya MN, Saigusa T) Am J Physiol Cell Physiol 2014 Sep 15;307(6):C554-60 11 Citations |
| 1 | Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer. (Liu S, Meng X, Chen H, Liu W, Miller T, Murph M, Lu Y, Zhang F, Gagea M, Arteaga CL, Mills GB, Meric-Bernstam F, González-Angulo AM) Oncotarget 2014 Oct 15;5(19):9049-64 23 Citations |
| 1 | Post-translational regulation of COX2 activity by FYN in prostate cancer cells. (Alexanian A, Miller B, Chesnik M, Mirza S, Sorokin A) Oncotarget 2014 Jun 30;5(12):4232-43 23 Citations |
| 1 | Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression. (Gao M, Zhao D, Schouteden S, Sorci-Thomas MG, Van Veldhoven PP, Eggermont K, Liu G, Verfaillie CM, Feng Y) Arterioscler Thromb Vasc Biol 2014 Sep;34(9):1900-9 60 Citations |
| 2 | Activation of the renin-angiotensin system, specifically in the subfornical organ is sufficient to induce fluid intake. (Coble JP, Cassell MD, Davis DR, Grobe JL, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2014 Aug 15;307(4):R376-86 23 Citations |
| 3 | Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer. (Qi X, Xie C, Hou S, Li G, Yin N, Dong L, Lepp A, Chesnik MA, Mirza SP, Szabo A, Tsai S, Basir Z, Wu S, Chen G) Oncotarget 2014 Jun 30;5(12):4269-82 20 Citations |
| 2 | Platelet-rich plasma extract prevents pulmonary edema through angiopoietin-Tie2 signaling. (Mammoto T, Jiang A, Jiang E, Mammoto A) Am J Respir Cell Mol Biol 2015 Jan;52(1):56-64 19 Citations |
| 1 | Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on natural killer cell function. (Yea SS, So L, Mallya S, Lee J, Rajasekaran K, Malarkannan S, Fruman DA) PLoS One 2014;9(6):e99486 11 Citations |
| 1 | Inhibition of food intake by PACAP in the hypothalamic ventromedial nuclei is mediated by NMDA receptors. (Resch JM, Maunze B, Phillips KA, Choi S) Physiol Behav 2014 Jun 22;133:230-5 32 Citations |
| 4 | Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure. (Lakshmikanthan S, Zieba BJ, Ge ZD, Momotani K, Zheng X, Lund H, Artamonov MV, Maas JE, Szabo A, Zhang DX, Auchampach JA, Mattson DL, Somlyo AV, Chrzanowska-Wodnicka M) Arterioscler Thromb Vasc Biol 2014 Jul;34(7):1486-94 49 Citations |
| 1 | O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. (Olivier-Van Stichelen S, Dehennaut V, Buzy A, Zachayus JL, Guinez C, Mir AM, El Yazidi-Belkoura I, Copin MC, Boureme D, Loyaux D, Ferrara P, Lefebvre T) FASEB J 2014 Aug;28(8):3325-38 128 Citations |
| 2 | Nitric oxide induces ataxia telangiectasia mutated (ATM) protein-dependent γH2AX protein formation in pancreatic β cells. (Oleson BJ, Broniowska KA, Schreiber KH, Tarakanova VL, Corbett JA) J Biol Chem 2014 Apr 18;289(16):11454-11464 28 Citations |
| 3 | Nogo-B receptor modulates angiogenesis response of pulmonary artery endothelial cells through eNOS coupling. (Teng RJ, Rana U, Afolayan AJ, Zhao B, Miao QR, Konduri GG) Am J Respir Cell Mol Biol 2014 Aug;51(2):169-77 20 Citations |
| 1 | Activation of protein kinase PKR requires dimerization-induced cis-phosphorylation within the activation loop. (Dey M, Mann BR, Anshu A, Mannan MA) J Biol Chem 2014 Feb 28;289(9):5747-57 48 Citations |
| 1 | Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. (Mounce BC, Mboko WP, Kanack AJ, Tarakanova VL) J Virol 2014 Feb;88(4):2268-78 19 Citations |
| 1 | Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. (Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G) Oncogene 2015 Jan 02;34(1):119-28 28 Citations |
| 1 | Protein-tyrosine phosphatase H1 increases breast cancer sensitivity to antiestrogens by dephosphorylating estrogen receptor at Tyr537. (Suresh PS, Ma S, Migliaccio A, Chen G) Mol Cancer Ther 2014 Jan;13(1):230-8 23 Citations |
| 1 | Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction. (Srinivasan S, Spear J, Chandran K, Joseph J, Kalyanaraman B, Avadhani NG) PLoS One 2013;8(10):e77129 56 Citations |
| 1 | Autophagy sensitivity of neuroendocrine lung tumor cells. (Hong SK, Kim JH, Starenki D, Park JI) Int J Oncol 2013 Dec;43(6):2031-8 12 Citations |
| 3 | AMPA receptor subunits expression and phosphorylation in cingulate cortex in rats following esophageal acid exposure. (Banerjee B, Medda BK, Pochiraju S, Kannampalli P, Lang IM, Sengupta JN, Shaker R) Neurogastroenterol Motil 2013 Dec;25(12):973-e776 9 Citations |
| 1 | HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol-induced parenchymal cell injury. (Seo YS, Kwon JH, Yaqoob U, Yang L, De Assuncao TM, Simonetto DA, Verma VK, Shah VH) Am J Physiol Gastrointest Liver Physiol 2013 Dec;305(11):G838-48 47 Citations |
| 1 | IreB, a Ser/Thr kinase substrate, influences antimicrobial resistance in Enterococcus faecalis. (Hall CL, Tschannen M, Worthey EA, Kristich CJ) Antimicrob Agents Chemother 2013 Dec;57(12):6179-86 54 Citations |
| 1 | STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity. (Betts BC, Veerapathran A, Pidala J, Yu XZ, Anasetti C) J Leukoc Biol 2014 Feb;95(2):205-13 28 Citations |
| 1 | Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. (Kang Y, Hu W, Ivan C, Dalton HJ, Miyake T, Pecot CV, Zand B, Liu T, Huang J, Jennings NB, Rupaimoole R, Taylor M, Pradeep S, Wu SY, Lu C, Wen Y, Huang J, Liu J, Sood AK) J Natl Cancer Inst 2013 Oct 02;105(19):1485-95 172 Citations |
| 1 | The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling. (Boulware MI, Heisler JD, Frick KM) J Neurosci 2013 Sep 18;33(38):15184-94 180 Citations |
| 1 | Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors. (Lane JR, Chubukov P, Liu W, Canals M, Cherezov V, Abagyan R, Stevens RC, Katritch V) Mol Pharmacol 2013 Dec;84(6):794-807 83 Citations |
| 1 | Pseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells. (Balczon R, Prasain N, Ochoa C, Prater J, Zhu B, Alexeyev M, Sayner S, Frank DW, Stevens T) PLoS One 2013;8(9):e74343 46 Citations |
| 2 | Canonical Wnt signaling is necessary for object recognition memory consolidation. (Fortress AM, Schram SL, Tuscher JJ, Frick KM) J Neurosci 2013 Jul 31;33(31):12619-26 100 Citations |
| 1 | Human cytomegalovirus IE1 protein disrupts interleukin-6 signaling by sequestering STAT3 in the nucleus. (Reitsma JM, Sato H, Nevels M, Terhune SS, Paulus C) J Virol 2013 Oct;87(19):10763-76 51 Citations |
| 1 | Thrombospondin-1 modulates VEGF signaling via CD36 by recruiting SHP-1 to VEGFR2 complex in microvascular endothelial cells. (Chu LY, Ramakrishnan DP, Silverstein RL) Blood 2013 Sep 05;122(10):1822-32 130 Citations |
| 1 | Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation. (Fox EM, Kuba MG, Miller TW, Davies BR, Arteaga CL) Breast Cancer Res 2013;15(4):R55 79 Citations |
| 1 | Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications. (Jiang Y, Janku F, Subbiah V, Angelo LS, Naing A, Anderson PM, Herzog CE, Fu S, Benjamin RS, Kurzrock R) Oncotarget 2013 Jun;4(6):884-9 31 Citations |
| 1 | Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. (Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X) J Clin Invest 2013 Jul;123(7):3084-98 137 Citations |
| 1 | The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. (Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C) Nat Immunol 2013 Jul;14(7):732-40 114 Citations |
| 1 | AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion. (Hong SK, Jeong JH, Chan AM, Park JI) Exp Cell Res 2013 Jul 15;319(12):1732-1743 21 Citations |
| 1 | Anxiolytic action of pterostilbene: involvement of hippocampal ERK phosphorylation. (Al Rahim M, Rimando AM, Silistreli K, El-Alfy AT) Planta Med 2013 Jun;79(9):723-30 22 Citations |
| 1 | Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding. (Bigley TM, Reitsma JM, Mirza SP, Terhune SS) J Virol 2013 Jul;87(13):7393-408 31 Citations |
| 2 | An ire1-phk1 chimera reveals a dispensable role of autokinase activity in endoplasmic reticulum stress response. (Mannan MA, Shadrick WR, Biener G, Shin BS, Anshu A, Raicu V, Frick DN, Dey M) J Mol Biol 2013 Jun 26;425(12):2083-99 16 Citations |
| 1 | Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome. (Uzel G, Sampaio EP, Lawrence MG, Hsu AP, Hackett M, Dorsey MJ, Noel RJ, Verbsky JW, Freeman AF, Janssen E, Bonilla FA, Pechacek J, Chandrasekaran P, Browne SK, Agharahimi A, Gharib AM, Mannurita SC, Yim JJ, Gambineri E, Torgerson T, Tran DQ, Milner JD, Holland SM) J Allergy Clin Immunol 2013 Jun;131(6):1611-23 273 Citations |
| 1 | Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus. (Fortress AM, Fan L, Orr PT, Zhao Z, Frick KM) Learn Mem 2013 Feb 19;20(3):147-55 131 Citations |
| 1 | RAS/MEK-independent gene expression reveals BMP2-related malignant phenotypes in the Nf1-deficient MPNST. (Sun D, Haddad R, Kraniak JM, Horne SD, Tainsky MA) Mol Cancer Res 2013 Jun;11(6):616-27 12 Citations |
| 4 | Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. (Tourdot BE, Brenner MK, Keough KC, Holyst T, Newman PJ, Newman DK) Biochemistry 2013 Apr 16;52(15):2597-608 39 Citations |
| 1 | Sickle cell vaso-occlusion causes activation of iNKT cells that is decreased by the adenosine A2A receptor agonist regadenoson. (Field JJ, Lin G, Okam MM, Majerus E, Keefer J, Onyekwere O, Ross A, Campigotto F, Neuberg D, Linden J, Nathan DG) Blood 2013 Apr 25;121(17):3329-34 89 Citations |
| 1 | LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation. (Menden H, Tate E, Hogg N, Sampath V) Am J Physiol Lung Cell Mol Physiol 2013 Mar 15;304(6):L445-55 59 Citations |
| 2 | Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling. (Chandrasekera PC, Wan TC, Gizewski ET, Auchampach JA, Lasley RD) Cell Signal 2013 Apr;25(4):736-42 38 Citations |
| 1 | Genetic and biochemical dissection of a HisKA domain identifies residues required exclusively for kinase and phosphatase activities. (Willett JW, Kirby JR) PLoS Genet 2012;8(11):e1003084 89 Citations |
| 1 | Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics. (Shepherd AJ, Loo L, Gupte RP, Mickle AD, Mohapatra DP) J Neurosci 2012 Dec 05;32(49):17725-39 31 Citations |
| 1 | HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. (Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X) PLoS One 2012;7(11):e49418 71 Citations |
| 1 | SMB myosin heavy chain knockout enhances tonic contraction and reduces the rate of force generation in ileum and stomach antrum. (Huang Q, Babu GJ, Periasamy M, Eddinger TJ) Am J Physiol Cell Physiol 2013 Jan 15;304(2):C194-206 7 Citations |
| 3 | AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension. (Teng RJ, Du J, Afolayan AJ, Eis A, Shi Y, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2013 Jan 01;304(1):L29-42 50 Citations |
| 1 | Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells. (Yu M, Chen Y, He Y, Podd A, Fu G, Wright JA, Kleiman E, Khan WN, Wen R, Wang D) J Immunol 2012 Dec 01;189(11):5185-93 17 Citations |
| 1 | HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells. (Florentin J, Aouar B, Dental C, Thumann C, Firaguay G, Gondois-Rey F, Soumelis V, Baumert TF, Nunès JA, Olive D, Hirsch I, Stranska R) Blood 2012 Nov 29;120(23):4544-51 53 Citations |
| 1 | Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition. (Drougat L, Olivier-Van Stichelen S, Mortuaire M, Foulquier F, Lacoste AS, Michalski JC, Lefebvre T, Vercoutter-Edouart AS) Biochim Biophys Acta 2012 Dec;1820(12):1839-48 58 Citations |
| 1 | The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin. (Gantner BN, Jin H, Qian F, Hay N, He B, Ye RD) J Immunol 2012 Sep 15;189(6):3104-11 29 Citations |
| 1 | Stress-induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei. (Esparza MA, Bollati F, Garcia-Keller C, Virgolini MB, Lopez LM, Brusco A, Shen HW, Kalivas PW, Cancela LM) Eur J Neurosci 2012 Oct;36(8):3103-17 27 Citations |
| 1 | Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a. (Fehr AR, Gualberto NC, Savaryn JP, Terhune SS, Yu D) PLoS Pathog 2012;8(7):e1002789 31 Citations |
| 2 | p38γ Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response. (Hou S, Suresh PS, Qi X, Lepp A, Mirza SP, Chen G) J Biol Chem 2012 Aug 10;287(33):27895-905 25 Citations |
| 1 | The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation. (Jarome TJ, Kwapis JL, Werner CT, Parsons RG, Gafford GM, Helmstetter FJ) Learn Mem 2012 Jun 20;19(7):300-6 43 Citations |
| 1 | Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion. (Park YM, Drazba JA, Vasanji A, Egelhoff T, Febbraio M, Silverstein RL) Mol Biol Cell 2012 Aug;23(16):3057-68 58 Citations |
| 1 | Effect of exercise on mouse liver and brain bioenergetic infrastructures. (E L, Lu J, Burns JM, Swerdlow RH) Exp Physiol 2013 Jan;98(1):207-19 37 Citations |
| 1 | PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors. (Meric-Bernstam F, Akcakanat A, Chen H, Do KA, Sangai T, Adkins F, Gonzalez-Angulo AM, Rashid A, Crosby K, Dong M, Phan AT, Wolff RA, Gupta S, Mills GB, Yao J) Clin Cancer Res 2012 Mar 15;18(6):1777-89 195 Citations |
| 2 | p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription. (Qi X, Zhi H, Lepp A, Wang P, Huang J, Basir Z, Chitambar CR, Myers CR, Chen G) J Biol Chem 2012 Apr 27;287(18):14681-91 26 Citations |
| 1 | Relative deficiency of acidic isoforms of osteopontin from stone former urine. (Kolbach AM, Afzal O, Halligan B, Sorokina E, Kleinman JG, Wesson JA) Urol Res 2012 Oct;40(5):447-54 16 Citations |
| 1 | Map kinase phosphatase 5 protects against sepsis-induced acute lung injury. (Qian F, Deng J, Gantner BN, Flavell RA, Dong C, Christman JW, Ye RD) Am J Physiol Lung Cell Mol Physiol 2012 May 01;302(9):L866-74 49 Citations |
| 1 | Identification of a redox-sensitive switch within the JAK2 catalytic domain. (Smith JK, Patil CN, Patlolla S, Gunter BW, Booz GW, Duhé RJ) Free Radic Biol Med 2012 Mar 15;52(6):1101-10 33 Citations |
| 1 | The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus. (Orr PT, Rubin AJ, Fan L, Kent BA, Frick KM) Horm Behav 2012 Apr;61(4):487-95 37 Citations |
| 1 | Latency-associated peptide of transforming growth factor-β1 is not subject to physiological mannose phosphorylation. (Barnes J, Warejcka D, Simpliciano J, Twining S, Steet R) J Biol Chem 2012 Mar 02;287(10):7526-34 10 Citations |
| 1 | CD36 ectodomain phosphorylation blocks thrombospondin-1 binding: structure-function relationships and regulation by protein kinase C. (Chu LY, Silverstein RL) Arterioscler Thromb Vasc Biol 2012 Mar;32(3):760-7 33 Citations |
| 2 | A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. (Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF) Blood 2012 Feb 23;119(8):1935-45 53 Citations |
| 1 | Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase. (Wang J, Alexanian A, Ying R, Kizhakekuttu TJ, Dharmashankar K, Vasquez-Vivar J, Gutterman DD, Widlansky ME) Arterioscler Thromb Vasc Biol 2012 Mar;32(3):712-20 118 Citations |
| 2 | Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology. (Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R) J Biol Chem 2012 Mar 02;287(10):7010-25 38 Citations |
| 1 | The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium. (Balko JM, Miller TW, Morrison MM, Hutchinson K, Young C, Rinehart C, Sánchez V, Jee D, Polyak K, Prat A, Perou CM, Arteaga CL, Cook RS) Proc Natl Acad Sci U S A 2012 Jan 03;109(1):221-6 57 Citations |
| 1 | Neuroprotection of paclitaxel against cerebral ischemia/reperfusion-induced brain injury through JNK3 signaling pathway. (Qi SH, Zhao H, Gong JJ, Sun FM, Yue J, Guan QH, Wang M) J Recept Signal Transduct Res 2011 Dec;31(6):402-7 7 Citations |
| 1 | Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and application in ligand identification of P-type lectins. (Song X, Heimburg-Molinaro J, Dahms NM, Smith DF, Cummings RD) Methods Mol Biol 2012;808:137-48 12 Citations |
| 2 | Reciprocal regulation of cephalosporin resistance in Enterococcus faecalis. (Kristich CJ, Little JL, Hall CL, Hoff JS) mBio 2011;2(6):e00199-11 62 Citations |
| 1 | Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway. (Mao M, Sudhahar V, Ansenberger-Fricano K, Fernandes DC, Tanaka LY, Fukai T, Laurindo FR, Mason RP, Vasquez-Vivar J, Minshall RD, Stadler K, Bonini MG) Free Radic Biol Med 2012 Jan 15;52(2):427-35 22 Citations |
| 1 | R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis. (Huang HJ, Angelo LS, Rodon J, Sun M, Kuenkele KP, Parsons HA, Trent JC, Kurzrock R) PLoS One 2011;6(10):e26060 38 Citations |
| 2 | Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA. (Zimmerman NP, Kumar SN, Turner JR, Dwinell MB) Inflamm Bowel Dis 2012 Jun;18(6):1081-91 35 Citations |
| 1 | The antiproliferative effects of pterostilbene on breast cancer in vitro are via inhibition of constitutive and leptin-induced Janus kinase/signal transducer and activator of transcription activation. (McCormack D, Schneider J, McDonald D, McFadden D) Am J Surg 2011 Nov;202(5):541-4 41 Citations |
| 1 | Combining curcumin (diferuloylmethane) and heat shock protein inhibition for neurofibromatosis 2 treatment: analysis of response and resistance pathways. (Angelo LS, Wu JY, Meng F, Sun M, Kopetz S, McCutcheon IE, Slopis JM, Kurzrock R) Mol Cancer Ther 2011 Nov;10(11):2094-103 30 Citations |
| 1 | CrdS and CrdA comprise a two-component system that is cooperatively regulated by the Che3 chemosensory system in Myxococcus xanthus. (Willett JW, Kirby JR) mBio 2011;2(4) 25 Citations |
| 1 | Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. (Leucker TM, Bienengraeber M, Muravyeva M, Baotic I, Weihrauch D, Brzezinska AK, Warltier DC, Kersten JR, Pratt PF Jr) J Mol Cell Cardiol 2011 Nov;51(5):803-11 60 Citations |
| 1 | Transforming growth factor-beta-activated kinase 1 regulates natural killer cell-mediated cytotoxicity and cytokine production. (Rajasekaran K, Chu H, Kumar P, Xiao Y, Tinguely M, Samarakoon A, Kim TW, Li X, Thakar MS, Zhang J, Malarkannan S) J Biol Chem 2011 Sep 09;286(36):31213-24 29 Citations |
| 1 | Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo. (Vinnakota KC, Dash RK, Beard DA) J Biol Chem 2011 Sep 02;286(35):30816-30822 22 Citations |
| 2 | The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions. (Saini V, Staren DM, Ziarek JJ, Nashaat ZN, Campbell EM, Volkman BF, Marchese A, Majetschak M) J Biol Chem 2011 Sep 23;286(38):33466-77 87 Citations |
| 1 | Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. (Zhang J, Guy MJ, Norman HS, Chen YC, Xu Q, Dong X, Guner H, Wang S, Kohmoto T, Young KH, Moss RL, Ge Y) J Proteome Res 2011 Sep 02;10(9):4054-65 165 Citations |
| 1 | NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury. (Cook DR, Gleichman AJ, Cross SA, Doshi S, Ho W, Jordan-Sciutto KL, Lynch DR, Kolson DL) J Neurochem 2011 Sep;118(6):1113-23 63 Citations |
| 1 | Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoprotein. (Young LC, Bone KM, Wang P, Wu F, Adam BA, Hegazy S, Gelebart P, Holovati J, Li L, Andrew SE, Lai R) Am J Pathol 2011 Jul;179(1):411-21 13 Citations |
| 1 | PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. (Adapala RK, Talasila PK, Bratz IN, Zhang DX, Suzuki M, Meszaros JG, Thodeti CK) Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H757-65 87 Citations |
| 2 | Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid. (Singh SK, Baumgart S, Singh G, König AO, Reutlinger K, Hofbauer LC, Barth P, Gress TM, Lomberk G, Urrutia R, Fernandez-Zapico ME, Ellenrieder V) J Biol Chem 2011 Aug 19;286(33):28761-28771 23 Citations |
| 3 | Neuronal plasticity in the cingulate cortex of rats following esophageal acid exposure in early life. (Banerjee B, Medda BK, Schmidt J, Lang IM, Sengupta JN, Shaker R) Gastroenterology 2011 Aug;141(2):544-52 11 Citations |
| 2 | Targeted intestinal epithelial deletion of the chemokine receptor CXCR4 reveals important roles for extracellular-regulated kinase-1/2 in restitution. (Zimmerman NP, Vongsa RA, Faherty SL, Salzman NH, Dwinell MB) Lab Invest 2011 Jul;91(7):1040-55 30 Citations |
| 1 | Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activity. (Sayner SL, Balczon R, Frank DW, Cooper DM, Stevens T) Am J Physiol Lung Cell Mol Physiol 2011 Jul;301(1):L117-24 37 Citations |
| 5 | Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. (Paddock C, Lytle BL, Peterson FC, Holyst T, Newman PJ, Volkman BF, Newman DK) Blood 2011 Jun 02;117(22):6012-23 38 Citations |
| 1 | The cAMP-responsive Rap1 guanine nucleotide exchange factor, Epac, induces smooth muscle relaxation by down-regulation of RhoA activity. (Zieba BJ, Artamonov MV, Jin L, Momotani K, Ho R, Franke AS, Neppl RL, Stevenson AS, Khromov AS, Chrzanowska-Wodnicka M, Somlyo AV) J Biol Chem 2011 May 13;286(19):16681-92 93 Citations |
| 1 | Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state. (Chen K, Li W, Major J, Rahaman SO, Febbraio M, Silverstein RL) Blood 2011 May 26;117(21):5744-50 59 Citations |
| 1 | Requirement for kinase-induced conformational change in eukaryotic initiation factor 2alpha (eIF2alpha) restricts phosphorylation of Ser51. (Dey M, Velyvis A, Li JJ, Chiu E, Chiovitti D, Kay LE, Sicheri F, Dever TE) Proc Natl Acad Sci U S A 2011 Mar 15;108(11):4316-21 19 Citations |
| 1 | Identification of phosphorylation sites on extracellular corneal epithelial cell maspin. (Narayan M, Mirza SP, Twining SS) Proteomics 2011 Apr;11(8):1382-90 11 Citations |
| 1 | The effect of adrenalectomy on the cardiac response to subacute fetal anemia. (Jonker SS, Scholz TD, Segar JL) Can J Physiol Pharmacol 2011 Feb;89(2):79-88 9 Citations |
| 1 | Neurogranin phosphorylation fine-tunes long-term potentiation. (Zhong L, Kaleka KS, Gerges NZ) Eur J Neurosci 2011 Jan;33(2):244-50 24 Citations |
| 1 | Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression. (McCormick ME, Goel R, Fulton D, Oess S, Newman D, Tzima E) Arterioscler Thromb Vasc Biol 2011 Mar;31(3):643-9 35 Citations |
| 1 | Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. (Konson A, Pradeep S, D'Acunto CW, Seger R) J Biol Chem 2011 Feb 04;286(5):3540-51 33 Citations |
| 1 | Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-β type I receptor. (Yu N, Kozlowski JM, Park II, Chen L, Zhang Q, Xu D, Doll JA, Crawford SE, Brendler CB, Lee C) Urology 2010 Dec;76(6):1519.e8-13 28 Citations |
| 2 | Structural and functional insights into core ABA signaling. (Weiner JJ, Peterson FC, Volkman BF, Cutler SR) Curr Opin Plant Biol 2010 Oct;13(5):495-502 221 Citations |
| 1 | Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. (Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V) Biochem J 2010 Nov 15;432(1):9-19 202 Citations |
| 1 | Nogo-B receptor is essential for angiogenesis in zebrafish via Akt pathway. (Zhao B, Chun C, Liu Z, Horswill MA, Pramanik K, Wilkinson GA, Ramchandran R, Miao RQ) Blood 2010 Dec 09;116(24):5423-33 51 Citations |
| 1 | A new pyrimidine-specific reporter gene: a mutated human deoxycytidine kinase suitable for PET during treatment with acycloguanosine-based cytotoxic drugs. (Likar Y, Zurita J, Dobrenkov K, Shenker L, Cai S, Neschadim A, Medin JA, Sadelain M, Hricak H, Ponomarev V) J Nucl Med 2010 Sep;51(9):1395-403 59 Citations |
| 2 | Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells. (Moraes LA, Barrett NE, Jones CI, Holbrook LM, Spyridon M, Sage T, Newman DK, Gibbins JM) J Thromb Haemost 2010 Nov;8(11):2530-41 41 Citations |
| 2 | Mitochondrial free [Ca2+] increases during ATP/ADP antiport and ADP phosphorylation: exploration of mechanisms. (Haumann J, Dash RK, Stowe DF, Boelens AD, Beard DA, Camara AK) Biophys J 2010 Aug 09;99(4):997-1006 31 Citations |
| 1 | Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation. (Bledzka K, Bialkowska K, Nie H, Qin J, Byzova T, Wu C, Plow EF, Ma YQ) J Biol Chem 2010 Oct 01;285(40):30370-4 46 Citations |
| 1 | The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors. (Kraniak JM, Sun D, Mattingly RR, Reiners JJ Jr, Tainsky MA) Mol Cell Biochem 2010 Nov;344(1-2):267-76 12 Citations |
| 1 | Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype. (Cao Y, Szabolcs A, Dutta SK, Yaqoob U, Jagavelu K, Wang L, Leof EB, Urrutia RA, Shah VH, Mukhopadhyay D) J Biol Chem 2010 Oct 08;285(41):31840-8 79 Citations |
| 1 | Angiotensin-(1-7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats. (Costa MA, Lopez Verrilli MA, Gomez KA, Nakagawa P, Peña C, Arranz C, Gironacci MM) Am J Physiol Heart Circ Physiol 2010 Oct;299(4):H1205-11 58 Citations |
| 1 | Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. (Konson A, Pradeep S, Seger R) Cancer Res 2010 Aug 01;70(15):6247-57 33 Citations |
| 1 | Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer. (Miller TW, Hennessy BT, González-Angulo AM, Fox EM, Mills GB, Chen H, Higham C, García-Echeverría C, Shyr Y, Arteaga CL) J Clin Invest 2010 Jul;120(7):2406-13 477 Citations |
| 2 | PECAM-1 functions as a negative regulator of laminin-induced platelet activation. (Crockett J, Newman DK, Newman PJ) J Thromb Haemost 2010 Jul;8(7):1584-93 18 Citations |
| 1 | Bradykinin B2 receptor interacts with integrin alpha5beta1 to transactivate epidermal growth factor receptor in kidney cells. (Kramarenko II, Bunni MA, Raymond JR, Garnovskaya MN) Mol Pharmacol 2010 Jul;78(1):126-34 17 Citations |
| 1 | Phosphatidylinositol 3-kinase regulates macrophage responses to double-stranded RNA and encephalomyocarditis virus. (Freudenburg W, Moran JM, Lents NH, Baldassare JJ, Buller RM, Corbett JA) J Innate Immun 2010;2(1):77-86 15 Citations |
| 1 | Estradiol-induced object memory consolidation in middle-aged female mice requires dorsal hippocampal extracellular signal-regulated kinase and phosphatidylinositol 3-kinase activation. (Fan L, Zhao Z, Orr PT, Chambers CH, Lewis MC, Frick KM) J Neurosci 2010 Mar 24;30(12):4390-400 138 Citations |
| 2 | PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction. (Hou SW, Zhi HY, Pohl N, Loesch M, Qi XM, Li RS, Basir Z, Chen G) Cancer Res 2010 Apr 01;70(7):2901-10 67 Citations |
| 2 | p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9. (Loesch M, Zhi HY, Hou SW, Qi XM, Li RS, Basir Z, Iftner T, Cuenda A, Chen G) J Biol Chem 2010 May 14;285(20):15149-15158 83 Citations |
| 1 | Burns, inflammation, and intestinal injury: protective effects of an anti-inflammatory resuscitation strategy. (Costantini TW, Peterson CY, Kroll L, Loomis WH, Putnam JG, Wolf P, Eliceiri BP, Baird A, Bansal V, Coimbra R) J Trauma 2009 Dec;67(6):1162-8 42 Citations |
| 1 | Design of experiments for identification of complex biochemical systems with applications to mitochondrial bioenergetics. (Vinnakota KC, Beard DA, Dash RK) Annu Int Conf IEEE Eng Med Biol Soc 2009;2009:4171-4 1 Citation |
| 1 | Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells. (Miller TW, Forbes JT, Shah C, Wyatt SK, Manning HC, Olivares MG, Sanchez V, Dugger TC, de Matos Granja N, Narasanna A, Cook RS, Kennedy JP, Lindsley CW, Arteaga CL) Clin Cancer Res 2009 Dec 01;15(23):7266-76 115 Citations |
| 2 | Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). (Rafiee P, Stein DJ, Nelson VM, Otterson MF, Shaker R, Binion DG) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G167-76 38 Citations |
| 2 | E2F3 is a mediator of DNA damage-induced apoptosis. (Martinez LA, Goluszko E, Chen HZ, Leone G, Post S, Lozano G, Chen Z, Chauchereau A) Mol Cell Biol 2010 Jan;30(2):524-36 69 Citations |
| 1 | The role of arrestin alpha-helix I in receptor binding. (Vishnivetskiy SA, Francis D, Van Eps N, Kim M, Hanson SM, Klug CS, Hubbell WL, Gurevich VV) J Mol Biol 2010 Jan 08;395(1):42-54 58 Citations |
| 2 | Cation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sites. (Bohnsack RN, Song X, Olson LJ, Kudo M, Gotschall RR, Canfield WM, Cummings RD, Smith DF, Dahms NM) J Biol Chem 2009 Dec 11;284(50):35215-26 64 Citations |
| 1 | Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model. (Gong J, Yang DJ, Kohanim S, Angelo LS, Kurzrock R) Cancer Biol Ther 2009 Dec;8(23):2239-47 2 Citations |
| 1 | Noncatalytic function of ERK1/2 can promote Raf/MEK/ERK-mediated growth arrest signaling. (Hong SK, Yoon S, Moelling C, Arthan D, Park JI) J Biol Chem 2009 Nov 27;284(48):33006-18 74 Citations |
| 1 | Endothelin-1 induces p66Shc activation through EGF receptor transactivation: Role of beta(1)Pix/Galpha(i3) interaction. (Chahdi A, Sorokin A) Cell Signal 2010 Feb;22(2):325-9 26 Citations |
| 2 | Glycan microarray analysis of P-type lectins reveals distinct phosphomannose glycan recognition. (Song X, Lasanajak Y, Olson LJ, Boonen M, Dahms NM, Kornfeld S, Cummings RD, Smith DF) J Biol Chem 2009 Dec 11;284(50):35201-14 61 Citations |
| 1 | Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly. (Jia L, Kaur J, Stuart RA) Eukaryot Cell 2009 Nov;8(11):1792-802 42 Citations |
| 1 | Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways. (Yin W, Park JI, Loeser RF) J Biol Chem 2009 Nov 13;284(46):31972-81 165 Citations |
| 2 | Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I. (Du J, Wei N, Xu H, Ge Y, Vásquez-Vivar J, Guan T, Oldham KT, Pritchard KA Jr, Shi Y) Arterioscler Thromb Vasc Biol 2009 Dec;29(12):2161-8 11 Citations |
| 1 | 20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site. (Chen Y, Falck JR, Tuniki VR, Campbell WB) J Pharmacol Exp Ther 2009 Dec;331(3):1137-45 26 Citations |
| 1 | Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1. (Teriete P, Thai K, Choi J, Marassi FM) Biochim Biophys Acta 2009 Nov;1788(11):2462-70 22 Citations |
| 1 | Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2. (McEwen ST, Balus SF, Durand MJ, Lombard JH) Am J Physiol Heart Circ Physiol 2009 Oct;297(4):H1296-303 17 Citations |
| 1 | Role of p38 MAPK in burn-induced intestinal barrier breakdown. (Costantini TW, Peterson CY, Kroll L, Loomis WH, Eliceiri BP, Baird A, Bansal V, Coimbra R) J Surg Res 2009 Sep;156(1):64-9 74 Citations |
| 2 | 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. (Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F) Am J Physiol Renal Physiol 2009 Sep;297(3):F662-70 47 Citations |
| 1 | The C-terminal Src inhibitory kinase (Csk)-mediated tyrosine phosphorylation is a novel molecular mechanism to limit P2X3 receptor function in mouse sensory neurons. (D'Arco M, Giniatullin R, Leone V, Carloni P, Birsa N, Nair A, Nistri A, Fabbretti E) J Biol Chem 2009 Aug 07;284(32):21393-401 41 Citations |
| 1 | Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development. (Freeman-Anderson NE, Zheng Y, McCalla-Martin AC, Treanor LM, Zhao YD, Garfin PM, He TC, Mary MN, Thornton JD, Anderson C, Gibbons M, Saab R, Baumer SH, Cunningham JM, Skapek SX) Development 2009 Jun;136(12):2081-9 30 Citations |
| 1 | She3p possesses a novel activity required for ASH1 mRNA localization in Saccharomyces cerevisiae. (Landers SM, Gallas MR, Little J, Long RM) Eukaryot Cell 2009 Jul;8(7):1072-83 15 Citations |
| 1 | Epidermal growth factor activates Na(+/)H(+) exchanger in podocytes through a mechanism that involves Janus kinase and calmodulin. (Coaxum SD, Garnovskaya MN, Gooz M, Baldys A, Raymond JR) Biochim Biophys Acta 2009 Jul;1793(7):1174-81 46 Citations |
| 1 | Primers on molecular pathways--the insulin pathway. (Lomberk G, Urrutia R) Pancreatology 2009;9(3):203-5 5 Citations |
| 1 | Dose-dependent effects of post-training estradiol plus progesterone treatment on object memory consolidation and hippocampal extracellular signal-regulated kinase activation in young ovariectomized mice. (Harburger LL, Saadi A, Frick KM) Neuroscience 2009 Apr 21;160(1):6-12 51 Citations |
| 1 | Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor. (Baldys A, Göoz M, Morinelli TA, Lee MH, Raymond JR Jr, Luttrell LM, Raymond JR Sr) Biochemistry 2009 Feb 24;48(7):1462-73 41 Citations |
| 1 | p18Ink4c and p53 Act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor. (Saab R, Rodriguez-Galindo C, Matmati K, Rehg JE, Baumer SH, Khoury JD, Billups C, Neale G, Helton KJ, Skapek SX) Cancer Res 2009 Jan 15;69(2):440-8 23 Citations |
| 1 | The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction. (Bhandari D, Robia SL, Marchese A) Mol Biol Cell 2009 Mar;20(5):1324-39 78 Citations |
| 1 | A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2. (Gárriz A, Qiu H, Dey M, Seo EJ, Dever TE, Hinnebusch AG) Mol Cell Biol 2009 Mar;29(6):1592-607 29 Citations |
| 1 | Aromatase is phosphorylated in situ at serine-118. (Miller TW, Shin I, Kagawa N, Evans DB, Waterman MR, Arteaga CL) J Steroid Biochem Mol Biol 2008 Nov;112(1-3):95-101 45 Citations |
| 1 | Ischemic preconditioning phosphorylates mitogen-activated kinases and heat shock protein 27 in the diabetic rat heart. (Ebel D, Toma O, Appler S, Baumann K, Frässdorf J, Preckel B, Rösen P, Schlack W, Weber NC) Horm Metab Res 2009 Jan;41(1):10-5 9 Citations |
| 1 | ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells. (Shimizu A, Mammoto A, Italiano JE Jr, Pravda E, Dudley AC, Ingber DE, Klagsbrun M) J Biol Chem 2008 Oct 03;283(40):27230-8 91 Citations |
| 2 | Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets. (Boylan B, Gao C, Rathore V, Gill JC, Newman DK, Newman PJ) Blood 2008 Oct 01;112(7):2780-6 164 Citations |
| 1 | The yeast Aac2 protein exists in physical association with the cytochrome bc1-COX supercomplex and the TIM23 machinery. (Dienhart MK, Stuart RA) Mol Biol Cell 2008 Sep;19(9):3934-43 90 Citations |
| 1 | Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. (Wendt MK, Drury LJ, Vongsa RA, Dwinell MB) Gastroenterology 2008 Aug;135(2):508-17 46 Citations |
| 1 | G-protein binding features and regulation of the RalGDS family member, RGL2. (Ferro E, Magrini D, Guazzi P, Fischer TH, Pistolesi S, Pogni R, White GC, Trabalzini L) Biochem J 2008 Oct 01;415(1):145-54 7 Citations |
| 1 | A specific CD36-dependent signaling pathway is required for platelet activation by oxidized low-density lipoprotein. (Chen K, Febbraio M, Li W, Silverstein RL) Circ Res 2008 Jun 20;102(12):1512-9 164 Citations |
| 1 | Endothelin-1 couples betaPix to p66Shc: role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of Akt. (Chahdi A, Sorokin A) Mol Biol Cell 2008 Jun;19(6):2609-19 34 Citations |
| 1 | Telokin expression and the effect of hypoxia on its phosphorylation status in smooth muscle cells from small and large pulmonary arteries. (Madden JA, Dantuma MW, Sorokina EA, Weihrauch D, Kleinman JG) Am J Physiol Lung Cell Mol Physiol 2008 Jun;294(6):L1166-73 10 Citations |
| 2 | Identification and characterization of the unique guanine nucleotide exchange factor, SmgGDS, in vascular smooth muscle cells. (Thill R, Campbell WB, Williams CL) J Cell Biochem 2008 Aug 01;104(5):1760-70 6 Citations |
| 1 | Double-stranded RNA-activated protein kinase PKR of fishes and amphibians: varying the number of double-stranded RNA binding domains and lineage-specific duplications. (Rothenburg S, Deigendesch N, Dey M, Dever TE, Tazi L) BMC Biol 2008 Mar 03;6:12 69 Citations |
| 1 | 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. (Medhora M, Chen Y, Gruenloh S, Harland D, Bodiga S, Zielonka J, Gebremedhin D, Gao Y, Falck JR, Anjaiah S, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2008 May;294(5):L902-11 69 Citations |
| 1 | Formation of smooth muscle alpha actin filaments in CD34+ bone marrow cells on arterial elastic laminae: potential role of SH2 domain-containing protein tyrosine phosphatase-1. (Liu SQ, Tefft BJ, Zhang A, Zhang LQ, Wu YH) Matrix Biol 2008 May;27(4):282-94 6 Citations |
| 1 | Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. (Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F) Cell 2008 Jan 11;132(1):89-100 303 Citations |
| 1 | The F1F0-ATP synthase complex influences the assembly state of the cytochrome bc1-cytochrome oxidase supercomplex and its association with the TIM23 machinery. (Saddar S, Dienhart MK, Stuart RA) J Biol Chem 2008 Mar 14;283(11):6677-86 55 Citations |
| 1 | Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. (Chahdi A, Sorokin A) Mol Cell Biol 2008 Mar;28(5):1679-87 40 Citations |
| 1 | 20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling. (Cheng J, Ou JS, Singh H, Falck JR, Narsimhaswamy D, Pritchard KA Jr, Schwartzman ML) Am J Physiol Heart Circ Physiol 2008 Feb;294(2):H1018-26 139 Citations |
| 1 | Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. (Tarakanova VL, Leung-Pineda V, Hwang S, Yang CW, Matatall K, Basson M, Sun R, Piwnica-Worms H, Sleckman BP, Virgin HW 4th) Cell Host Microbe 2007 Jun 14;1(4):275-86 125 Citations |
| 1 | G protein-coupled receptor sorting to endosomes and lysosomes. (Marchese A, Paing MM, Temple BR, Trejo J) Annu Rev Pharmacol Toxicol 2008;48:601-29 384 Citations |
| 1 | The regulation of mitochondrial respiration by opening of mKCa channels is age-dependent. (Heinen A, Winning A, Schlack W, Hollmann MW, Preckel B, Frässdorf J, Weber NC) Eur J Pharmacol 2008 Jan 14;578(2-3):108-13 20 Citations |
| 1 | Novel membrane-bound eIF2alpha kinase in the flagellar pocket of Trypanosoma brucei. (Moraes MC, Jesus TC, Hashimoto NN, Dey M, Schwartz KJ, Alves VS, Avila CC, Bangs JD, Dever TE, Schenkman S, Castilho BA) Eukaryot Cell 2007 Nov;6(11):1979-91 57 Citations |
| 2 | High-throughput phosphotyrosine profiling using SH2 domains. (Machida K, Thompson CM, Dierck K, Jablonowski K, Kärkkäinen S, Liu B, Zhang H, Nash PD, Newman DK, Nollau P, Pawson T, Renkema GH, Saksela K, Schiller MR, Shin DG, Mayer BJ) Mol Cell 2007 Jun 22;26(6):899-915 153 Citations |
| 1 | Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia. (Moyer RA, Wendt MK, Johanesen PA, Turner JR, Dwinell MB) Lab Invest 2007 Aug;87(8):807-17 70 Citations |
| 2 | Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. (Mammoto T, Parikh SM, Mammoto A, Gallagher D, Chan B, Mostoslavsky G, Ingber DE, Sukhatme VP) J Biol Chem 2007 Aug 17;282(33):23910-8 162 Citations |
| 1 | Platelet-derived growth factor receptor antagonist STI571 (imatinib mesylate) inhibits human vascular smooth muscle proliferation and migration in vitro but not in vivo. (Hacker TA, Griffin MO, Guttormsen B, Stoker S, Wolff MR) J Invasive Cardiol 2007 Jun;19(6):269-74 14 Citations |
| 1 | Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival. (Yuan HT, Venkatesha S, Chan B, Deutsch U, Mammoto T, Sukhatme VP, Woolf AS, Karumanchi SA) FASEB J 2007 Oct;21(12):3171-83 92 Citations |
| 1 | Phosphorylation of Bcl10 negatively regulates T-cell receptor-mediated NF-kappaB activation. (Zeng H, Di L, Fu G, Chen Y, Gao X, Xu L, Lin X, Wen R) Mol Cell Biol 2007 Jul;27(14):5235-45 33 Citations |
| 1 | Myosin II isoforms in smooth muscle: heterogeneity and function. (Eddinger TJ, Meer DP) Am J Physiol Cell Physiol 2007 Aug;293(2):C493-508 82 Citations |
| 1 | Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. (Uwagawa T, Li Z, Chang Z, Xia Q, Peng B, Sclabas GM, Ishiyama S, Hung MC, Evans DB, Abbruzzese JL, Chiao PJ) Cancer 2007 May 15;109(10):2142-53 43 Citations |
| 1 | The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. (Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani RA) Blood 2007 Jul 01;110(1):171-9 138 Citations |
| 1 | Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid. (Isenberg JS, Jia Y, Field L, Ridnour LA, Sparatore A, Del Soldato P, Sowers AL, Yeh GC, Moody TW, Wink DA, Ramchandran R, Roberts DD) Br J Pharmacol 2007 May;151(1):63-72 75 Citations |
| 1 | Structure and function of the visual arrestin oligomer. (Hanson SM, Van Eps N, Francis DJ, Altenbach C, Vishnivetskiy SA, Arshavsky VY, Klug CS, Hubbell WL, Gurevich VV) EMBO J 2007 Mar 21;26(6):1726-36 105 Citations |
| 1 | Protein kinase D 3 is localized in vesicular structures and interacts with vesicle-associated membrane protein 2. (Lu G, Chen J, Espinoza LA, Garfield S, Toshiyuki S, Akiko H, Huppler A, Wang QJ) Cell Signal 2007 Apr;19(4):867-79 28 Citations |
| 1 | E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. (Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G) Mol Cell Biol 2007 Jan;27(1):65-78 88 Citations |
| 1 | PGJ2-stimulated beta-cell apoptosis is associated with prolonged UPR activation. (Chambers KT, Weber SM, Corbett JA) Am J Physiol Endocrinol Metab 2007 Apr;292(4):E1052-61 18 Citations |
| 1 | Novel in vivo imaging shows up-regulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies. (Gong J, Yang D, Kohanim S, Humphreys R, Broemeling L, Kurzrock R) Mol Cancer Ther 2006 Dec;5(12):2991-3000 33 Citations |
| 1 | ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells. (Sarközi R, Miller B, Pollack V, Feifel E, Mayer G, Sorokin A, Schramek H) J Cell Physiol 2007 Apr;211(1):88-100 32 Citations |
| 2 | Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity. (Li QP, Qi X, Pramanik R, Pohl NM, Loesch M, Chen G) J Biol Chem 2007 Jan 19;282(3):1544-51 30 Citations |
| 1 | Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. (Turner JH, Garnovskaya MN, Coaxum SD, Vlasova TM, Yakutovich M, Lefler DM, Raymond JR) J Pharmacol Exp Ther 2007 Jan;320(1):314-22 21 Citations |
| 1 | Human papillomaviruses target the double-stranded RNA protein kinase pathway. (Hebner CM, Wilson R, Rader J, Bidder M, Laimins LA) J Gen Virol 2006 Nov;87(Pt 11):3183-3193 59 Citations |
| 1 | Proteomic analysis of acute promyelocytic leukemia: PML-RARalpha leads to decreased phosphorylation of OP18 at serine 63. (Zada AA, Geletu MH, Pulikkan JA, Müller-Tidow C, Reddy VA, Christopeit M, Hiddemann WD, Behre HM, Tenen DG, Behre G) Proteomics 2006 Nov;6(21):5705-19 14 Citations |
| 1 | A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. (Hu G, Tang J, Zhang B, Lin Y, Hanai J, Galloway J, Bedell V, Bahary N, Han Z, Ramchandran R, Thisse B, Thisse C, Zon LI, Sukhatme VP) J Cell Sci 2006 Oct 01;119(Pt 19):4117-26 62 Citations |
| 1 | Distinct biological impact of dephosphorylation vs. downregulation of p210Bcr-Abl: implications for imatinib mesylate response and resistance. (Kurzrock R, Talpaz M, Li L, Estrov Z) Leuk Lymphoma 2006 Aug;47(8):1651-64 2 Citations |
| 1 | Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells. (Pozdeyev N, Taylor C, Haque R, Chaurasia SS, Visser A, Thazyeen A, Du Y, Fu H, Weller J, Klein DC, Iuvone PM) J Neurosci 2006 Sep 06;26(36):9153-61 42 Citations |
| 1 | A CD36-dependent signaling cascade is necessary for macrophage foam cell formation. (Rahaman SO, Lennon DJ, Febbraio M, Podrez EA, Hazen SL, Silverstein RL) Cell Metab 2006 Sep;4(3):211-21 452 Citations |
| 1 | Insulin biosynthesis: the IREny of it all. (Corbett JA) Cell Metab 2006 Sep;4(3):175-6 5 Citations |
| 1 | Role of MAPK in the regulation of double-stranded RNA- and encephalomyocarditis virus-induced cyclooxygenase-2 expression by macrophages. (Steer SA, Moran JM, Christmann BS, Maggi LB Jr, Corbett JA) J Immunol 2006 Sep 01;177(5):3413-20 54 Citations |
| 1 | Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells. (Bauer TW, Somcio RJ, Fan F, Liu W, Johnson M, Lesslie DP, Evans DB, Gallick GE, Ellis LM) Mol Cancer Ther 2006 Jul;5(7):1676-82 94 Citations |
| 1 | Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation. (Maresso AW, Deng Q, Pereckas MS, Wakim BT, Barbieri JT) Cell Microbiol 2007 Jan;9(1):97-105 33 Citations |
| 1 | CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4. (Slagsvold T, Marchese A, Brech A, Stenmark H) EMBO J 2006 Aug 23;25(16):3738-49 62 Citations |
| 2 | p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion. (Qi X, Tang J, Loesch M, Pohl N, Alkan S, Chen G) Cancer Res 2006 Aug 01;66(15):7540-7 41 Citations |
| 1 | Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells. (Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE) Angiogenesis 2006;9(2):101-10 44 Citations |
| 2 | Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27. (Rafiee P, Theriot ME, Nelson VM, Heidemann J, Kanaa Y, Horowitz SA, Rogaczewski A, Johnson CP, Ali I, Shaker R, Binion DG) Am J Physiol Cell Physiol 2006 Nov;291(5):C931-45 83 Citations |
| 1 | 5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-alpha-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells. (Göőz M, Göőz P, Luttrell LM, Raymond JR) J Biol Chem 2006 Jul 28;281(30):21004-21012 99 Citations |
| 1 | Collagenase-2 and -3 mediate epidermal growth factor receptor transactivation by bradykinin B2 receptor in kidney cells. (Mukhin YV, Gooz M, Raymond JR, Garnovskaya MN) J Pharmacol Exp Ther 2006 Sep;318(3):1033-43 18 Citations |
| 2 | Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution. (Whitsett J, Martásek P, Zhao H, Schauer DW, Hatakeyama K, Kalyanaraman B, Vásquez-Vivar J) Free Radic Biol Med 2006 Jun 01;40(11):2056-68 36 Citations |
| 1 | Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells. (Chen Y, Medhora M, Falck JR, Pritchard KA Jr, Jacobs ER) Am J Physiol Lung Cell Mol Physiol 2006 Sep;291(3):L378-85 52 Citations |
| 1 | Proteasome-dependent down-regulation of activated Stat5A in the nucleus. (Chen Y, Dai X, Haas AL, Wen R, Wang D) Blood 2006 Jul 15;108(2):566-74 26 Citations |
| 1 | Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin. (Hanson SM, Francis DJ, Vishnivetskiy SA, Kolobova EA, Hubbell WL, Klug CS, Gurevich VV) Proc Natl Acad Sci U S A 2006 Mar 28;103(13):4900-5 170 Citations |
| 1 | Evidence for the existence of an HP1-mediated subcode within the histone code. (Lomberk G, Bensi D, Fernandez-Zapico ME, Urrutia R) Nat Cell Biol 2006 Apr;8(4):407-15 161 Citations |
| 1 | Evidence for absence of latch-bridge formation in muscular saphenous arteries. (Han S, Speich JE, Eddinger TJ, Berg KM, Miner AS, Call C, Ratz PH) Am J Physiol Heart Circ Physiol 2006 Jul;291(1):H138-46 16 Citations |
| 1 | A member of the transforming growth factor-beta receptor family from Echinococcus multilocularis is activated by human bone morphogenetic protein 2. (Zavala-Góngora R, Kroner A, Bernthaler P, Knaus P, Brehm K) Mol Biochem Parasitol 2006 Apr;146(2):265-71 43 Citations |
| 1 | Phosphatase localization in bacterial chemotaxis: divergent mechanisms, convergent principles. (Rao CV, Kirby JR, Arkin AP) Phys Biol 2005 Jul 14;2(3):148-58 22 Citations |
| 1 | Morphine induces late cardioprotection in rat hearts in vivo: the involvement of opioid receptors and nuclear transcription factor kappaB. (Frässdorf J, Weber NC, Obal D, Toma O, Müllenheim J, Kojda G, Preckel B, Schlack W) Anesth Analg 2005 Oct;101(4):934-941 51 Citations |
| 1 | Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. (Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME) J Virol 2005 Oct;79(20):12828-39 257 Citations |
| 1 | Mechanistic link between PKR dimerization, autophosphorylation, and eIF2alpha substrate recognition. (Dey M, Cao C, Dar AC, Tamura T, Ozato K, Sicheri F, Dever TE) Cell 2005 Sep 23;122(6):901-13 307 Citations |
| 1 | Negative regulation of monocyte adhesion to arterial elastic laminae by signal regulatory protein alpha and Src homology 2 domain-containing protein-tyrosine phosphatase-1. (Liu SQ, Alkema PK, Tieché C, Tefft BJ, Liu DZ, Li YC, Sumpio BE, Caprini JA, Paniagua M) J Biol Chem 2005 Nov 25;280(47):39294-301 39 Citations |
| 1 | Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation. (Rembold CM, Ripley ML, Meeks MK, Geddis LM, Kutchai HC, Marassi FM, Cheung JY, Moorman JR) J Vasc Res 2005;42(6):483-91 28 Citations |
| 1 | Uncoupling Crk signal transduction by Pseudomonas exoenzyme T. (Deng Q, Sun J, Barbieri JT) J Biol Chem 2005 Oct 28;280(43):35953-60 34 Citations |
| 2 | Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death. (Shang T, Joseph J, Hillard CJ, Kalyanaraman B) J Biol Chem 2005 Oct 14;280(41):34644-53 37 Citations |
| 1 | Specific pharmacological dimerization of KDR in lentivirally transduced human hematopoietic cells activates anti-apoptotic and proliferative mechanisms. (Siatskas C, Underwood J, Ramezani A, Hawley RG, Medin JA) FASEB J 2005 Oct;19(12):1752-4 10 Citations |
| 1 | Genetic and pharmacologic evidence that calcium-independent phospholipase A2beta regulates virus-induced inducible nitric-oxide synthase expression by macrophages. (Moran JM, Buller RM, McHowat J, Turk J, Wohltmann M, Gross RW, Corbett JA) J Biol Chem 2005 Jul 29;280(30):28162-8 55 Citations |
| 1 | Proteome of H-411E (liver) cells exposed to insulin and tumor necrosis factor-alpha: analysis of proteins involved in insulin resistance. (Solomon SS, Buss N, Shull J, Monnier S, Majumdar G, Wu J, Gerling IC) J Lab Clin Med 2005 May;145(5):275-83 33 Citations |
| 1 | Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors. (Gray MJ, Wey JS, Belcheva A, McCarty MF, Trevino JG, Evans DB, Ellis LM, Gallick GE) Cancer Res 2005 May 01;65(9):3664-70 85 Citations |
| 2 | Essential role of p38gamma in K-Ras transformation independent of phosphorylation. (Tang J, Qi X, Mercola D, Han J, Chen G) J Biol Chem 2005 Jun 24;280(25):23910-7 56 Citations |
| 1 | PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha. (Dey M, Trieselmann B, Locke EG, Lu J, Cao C, Dar AC, Krishnamoorthy T, Dong J, Sicheri F, Dever TE) Mol Cell Biol 2005 Apr;25(8):3063-75 61 Citations |
| 1 | Protein kinase C phosphorylation modulates N- and C-terminal regulatory activities of the PITX2 homeodomain protein. (Espinoza HM, Ganga M, Vadlamudi U, Martin DM, Brooks BP, Semina EV, Murray JC, Amendt BA) Biochemistry 2005 Mar 15;44(10):3942-54 26 Citations |
| 1 | HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. (Gray MJ, Zhang J, Ellis LM, Semenza GL, Evans DB, Watowich SS, Gallick GE) Oncogene 2005 Apr 28;24(19):3110-20 353 Citations |
| 1 | Role of phosphorylated CaMKII and calcineurin in the differential effect of hypothyroidism on LTP of CA1 and dentate gyrus. (Gerges NZ, Alzoubi KH, Alkadhi KA) Hippocampus 2005;15(4):480-90 55 Citations |
| 1 | Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. (Torrealba JR, Colburn M, Golner S, Chang Z, Scheunemann T, Fechner JH, Roenneburg D, Hu H, Alam T, Kim HT, Kanmaz T, Oberley T, Knechtle SJ, Hamawy MM) Am J Transplant 2005 Jan;5(1):58-67 17 Citations |
| 1 | The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38. (Zhao Q, Shepherd EG, Manson ME, Nelin LD, Sorokin A, Liu Y) J Biol Chem 2005 Mar 04;280(9):8101-8 197 Citations |
| 1 | Endothelin 1 induces beta 1Pix translocation and Cdc42 activation via protein kinase A-dependent pathway. (Chahdi A, Miller B, Sorokin A) J Biol Chem 2005 Jan 07;280(1):578-84 59 Citations |
| 1 | Unanticipated antigens: translation initiation at CUG with leucine. (Schwab SR, Shugart JA, Horng T, Malarkannan S, Shastri N) PLoS Biol 2004 Nov;2(11):e366 93 Citations |
| 1 | Interaction between protein kinase Cmu and the vanilloid receptor type 1. (Wang Y, Kedei N, Wang M, Wang QJ, Huppler AR, Toth A, Tran R, Blumberg PM) J Biol Chem 2004 Dec 17;279(51):53674-82 64 Citations |
| 1 | IC138 is a WD-repeat dynein intermediate chain required for light chain assembly and regulation of flagellar bending. (Hendrickson TW, Perrone CA, Griffin P, Wuichet K, Mueller J, Yang P, Porter ME, Sale WS) Mol Biol Cell 2004 Dec;15(12):5431-42 92 Citations |
| 1 | Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B. (Potthast R, Abbey-Hosch SE, Antos LK, Marchant JS, Kuhn M, Potter LR) J Biol Chem 2004 Nov 19;279(47):48513-9 33 Citations |
| 1 | PPARgamma ligands induce ER stress in pancreatic beta-cells: ER stress activation results in attenuation of cytokine signaling. (Weber SM, Chambers KT, Bensch KG, Scarim AL, Corbett JA) Am J Physiol Endocrinol Metab 2004 Dec;287(6):E1171-7 64 Citations |
| 1 | Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors. (Silvaggi NR, Kaur K, Adediran SA, Pratt RF, Kelly JA) Biochemistry 2004 Jun 08;43(22):7046-53 18 Citations |
| 1 | Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment. (El-Hashemite N, Zhang H, Walker V, Hoffmeister KM, Kwiatkowski DJ) Cancer Res 2004 May 15;64(10):3436-43 53 Citations |
| 1 | Reduced basal CaMKII levels in hippocampal CA1 region: possible cause of stress-induced impairment of LTP in chronically stressed rats. (Gerges NZ, Aleisa AM, Schwarz LA, Alkadhi KA) Hippocampus 2004;14(3):402-10 89 Citations |
| 1 | Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation. (Garnovskaya MN, Mukhin YV, Vlasova TM, Grewal JS, Ullian ME, Tholanikunnel BG, Raymond JR) J Biol Chem 2004 Jun 04;279(23):24899-905 36 Citations |
| 1 | Hypothyroidism impairs late LTP in CA1 region but not in dentate gyrus of the intact rat hippocampus: MAPK involvement. (Gerges NZ, Alkadhi KA) Hippocampus 2004;14(1):40-5 112 Citations |
| 1 | Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. (Ahmadian G, Ju W, Liu L, Wyszynski M, Lee SH, Dunah AW, Taghibiglou C, Wang Y, Lu J, Wong TP, Sheng M, Wang YT) EMBO J 2004 Mar 10;23(5):1040-50 247 Citations |
| 1 | Flagellar radial spoke protein 2 is a calmodulin binding protein required for motility in Chlamydomonas reinhardtii. (Yang P, Yang C, Sale WS) Eukaryot Cell 2004 Feb;3(1):72-81 52 Citations |
| 1 | Mucosal angiogenesis regulation by CXCR4 and its ligand CXCL12 expressed by human intestinal microvascular endothelial cells. (Heidemann J, Ogawa H, Rafiee P, Lügering N, Maaser C, Domschke W, Binion DG, Dwinell MB) Am J Physiol Gastrointest Liver Physiol 2004 Jun;286(6):G1059-68 67 Citations |
| 1 | Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. (Turner JH, Gelasco AK, Raymond JR) J Biol Chem 2004 Apr 23;279(17):17027-37 75 Citations |
| 1 | Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. (Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ) Clin Cancer Res 2003 Dec 15;9(17):6534-44 154 Citations |
| 1 | Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells. (Pivniouk VI, Snapper SB, Kettner A, Alenius H, Laouini D, Falet H, Hartwig J, Alt FW, Geha RS) Int Immunol 2003 Dec;15(12):1431-40 41 Citations |
| 1 | Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. (Schmidt C, Peng B, Li Z, Sclabas GM, Fujioka S, Niu J, Schmidt-Supprian M, Evans DB, Abbruzzese JL, Chiao PJ) Mol Cell 2003 Nov;12(5):1287-300 146 Citations |
| 2 | Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells. (Qi X, Borowicz S, Pramanik R, Schultz RM, Han J, Chen G) J Biol Chem 2004 Feb 20;279(8):6769-77 29 Citations |
| 1 | Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (Budisavljevic MN, Hodge L, Barber K, Fulmer JR, Durazo-Arvizu RA, Self SE, Kuhlmann M, Raymond JR, Greene EL) Am J Physiol Renal Physiol 2003 Dec;285(6):F1138-48 54 Citations |
| 1 | ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells. (Mukhin YV, Garnovskaya MN, Ullian ME, Raymond JR) J Biol Chem 2004 Jan 16;279(3):1845-52 41 Citations |
| 1 | Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells. (Pratt PF, Bokemeyer D, Foschi M, Sorokin A, Dunn MJ) J Biol Chem 2003 Dec 19;278(51):51928-36 37 Citations |
| 1 | CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth. (Strock CJ, Park JI, Rosen M, Dionne C, Ruggeri B, Jones-Bolin S, Denmeade SR, Ball DW, Nelkin BD) Cancer Res 2003 Sep 01;63(17):5559-63 92 Citations |
| 1 | Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. (Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA Jr, Sessa WC) J Biol Chem 2003 Nov 07;278(45):44719-26 222 Citations |
| 3 | Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. (Maas M, Wang R, Paddock C, Kotamraju S, Kalyanaraman B, Newman PJ, Newman DK) Am J Physiol Heart Circ Physiol 2003 Dec;285(6):H2336-44 21 Citations |
| 2 | PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. (Rathore V, Stapleton MA, Hillery CA, Montgomery RR, Nichols TC, Merricks EP, Newman DK, Newman PJ) Blood 2003 Nov 15;102(10):3658-64 79 Citations |
| 1 | The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system. (Gardino AK, Volkman BF, Cho HS, Lee SY, Wemmer DE, Kern D) J Mol Biol 2003 Aug 01;331(1):245-54 36 Citations |
| 1 | Phosphorylation of CREB and mechanical hyperalgesia is reversed by blockade of the cAMP pathway in a time-dependent manner after repeated intramuscular acid injections. (Hoeger-Bement MK, Sluka KA) J Neurosci 2003 Jul 02;23(13):5437-45 123 Citations |
| 1 | Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells. (Martinson BD, Albert CJ, Corbett JA, Wysolmerski RB, Ford DA) J Lipid Res 2003 Sep;44(9):1686-91 23 Citations |
| 1 | Mitogen-induced activation of Na+/H+ exchange in vascular smooth muscle cells involves janus kinase 2 and Ca2+/calmodulin. (Garnovskaya MN, Mukhin YV, Turner JH, Vlasova TM, Ullian ME, Raymond JR) Biochemistry 2003 Jun 17;42(23):7178-87 28 Citations |
| 1 | Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system. (Sriuranpong V, Park JI, Amornphimoltham P, Patel V, Nelkin BD, Gutkind JS) Cancer Res 2003 Jun 01;63(11):2948-56 255 Citations |
| 2 | Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. (Newman PJ, Newman DK) Arterioscler Thromb Vasc Biol 2003 Jun 01;23(6):953-64 364 Citations |
| 1 | Trichloroethylene decreases heat shock protein 90 interactions with endothelial nitric oxide synthase: implications for endothelial cell proliferation. (Ou J, Ou Z, McCarver DG, Hines RN, Oldham KT, Ackerman AW, Pritchard KA Jr) Toxicol Sci 2003 May;73(1):90-7 40 Citations |
| 1 | Chronic psychosocial stress decreases calcineurin in the dentate gyrus: a possible mechanism for preservation of early ltp. (Gerges NZ, Aleisa AM, Schwarz LA, Alkadhi KA) Neuroscience 2003;117(4):869-74 39 Citations |
| 1 | Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. (Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS) Mol Cell Biol 2003 Apr;23(7):2395-406 36 Citations |
| 1 | Hypertonicity activates Na+/H+ exchange through Janus kinase 2 and calmodulin. (Garnovskaya MN, Mukhin YV, Vlasova TM, Raymond JR) J Biol Chem 2003 May 09;278(19):16908-15 59 Citations |
| 1 | Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR. (Bais C, Van Geelen A, Eroles P, Mutlu A, Chiozzini C, Dias S, Silverstein RL, Rafii S, Mesri EA) Cancer Cell 2003 Feb;3(2):131-43 217 Citations |
| 1 | Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. (Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ) Oncogene 2003 Mar 06;22(9):1365-70 154 Citations |
| 1 | ERK activation is required for double-stranded RNA- and virus-induced interleukin-1 expression by macrophages. (Maggi LB Jr, Moran JM, Buller RM, Corbett JA) J Biol Chem 2003 May 09;278(19):16683-9 38 Citations |
| 1 | Plasma membrane Ca2+-ATPase isoform 4b is phosphorylated on tyrosine 1176 in activated human platelets. (Wan TC, Zabe M, Dean WL) Thromb Haemost 2003 Jan;89(1):122-31 31 Citations |
| 1 | Sustained tyrosine-phosphorylation of FAK through Rho-dependent adhesion to fibronectin is essential for cancer cell migration. (Mukai M, Togawa A, Imamura F, Iwasaki T, Ayaki M, Mammoto T, Nakamura H, Tatsuta M, Inoue M) Anticancer Res 2002;22(6A):3175-84 17 Citations |
| 1 | Modulation of the electrophoretic mobility of the linker for activation of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a potential substrate for PKC and calcineurin signaling pathways. (Cho CS, Elkahwaji J, Chang Z, Scheunemann TL, Manthei ER, Hamawy MM) Cell Signal 2003 Jan;15(1):85-93 12 Citations |
| 1 | Platelet-activating factor priming of inflammatory cell activity requires cellular adherence. (Cuschieri J, Gourlay D, Bulger E, Garcia I, Jelacic S, Maier RV) Surgery 2002 Aug;132(2):157-66 7 Citations |
| 3 | Nitration of PECAM-1 ITIM tyrosines abrogates phosphorylation and SHP-2 binding. (Newman DK, Hoffman S, Kotamraju S, Zhao T, Wakim B, Kalyanaraman B, Newman PJ) Biochem Biophys Res Commun 2002 Sep 06;296(5):1171-9 36 Citations |
| 2 | Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. (Shi Y, Baker JE, Zhang C, Tweddell JS, Su J, Pritchard KA Jr) Circ Res 2002 Aug 23;91(4):300-6 92 Citations |
| 1 | Reduced focal adhesion kinase and paxillin phosphorylation in BCR-ABL-transfected cells. (Cheng K, Kurzrock R, Qiu X, Estrov Z, Ku S, Dulski KM, Wang JY, Talpaz M) Cancer 2002 Jul 15;95(2):440-50 23 Citations |
| 4 | Activation of protein kinases in chronically hypoxic infant human and rabbit hearts: role in cardioprotection. (Rafiee P, Shi Y, Kong X, Pritchard KA Jr, Tweddell JS, Litwin SB, Mussatto K, Jaquiss RD, Su J, Baker JE) Circulation 2002 Jul 09;106(2):239-45 83 Citations |
| 1 | Native low-density lipoprotein induces endothelial nitric oxide synthase dysfunction: role of heat shock protein 90 and caveolin-1. (Pritchard KA, Ackerman AW, Ou J, Curtis M, Smalley DM, Fontana JT, Stemerman MB, Sessa WC) Free Radic Biol Med 2002 Jul 01;33(1):52-62 49 Citations |
| 1 | The activation of Rac1 by M3 muscarinic acetylcholine receptors involves the translocation of Rac1 and IQGAP1 to cell junctions and changes in the composition of protein complexes containing Rac1, IQGAP1, and actin. (Ruiz-Velasco R, Lanning CC, Williams CL) J Biol Chem 2002 Sep 06;277(36):33081-91 21 Citations |
| 1 | alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. (Montgomery DE, Wolska BM, Pyle WG, Roman BB, Dowell JC, Buttrick PM, Koretsky AP, Del Nido P, Solaro RJ) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H2397-405 59 Citations |
| 1 | A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome. (Espinoza HM, Cox CJ, Semina EV, Amendt BA) Hum Mol Genet 2002 Apr 01;11(7):743-53 58 Citations |
| 1 | The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease. (Fu Z, Wang M, Potter D, Miziorko HM, Kim JJ) J Biol Chem 2002 May 17;277(20):18134-42 110 Citations |
| 1 | Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1. (Hanai J, Dhanabal M, Karumanchi SA, Albanese C, Waterman M, Chan B, Ramchandran R, Pestell R, Sukhatme VP) J Biol Chem 2002 May 10;277(19):16464-9 223 Citations |
| 1 | Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. (Cook JG, Park CH, Burke TW, Leone G, DeGregori J, Engel A, Nevins JR) Proc Natl Acad Sci U S A 2002 Feb 05;99(3):1347-52 102 Citations |
| 1 | DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. (Lan Z, Sever-Chroneos Z, Strobeck MW, Park CH, Baskaran R, Edelmann W, Leone G, Knudsen ES) J Biol Chem 2002 Mar 08;277(10):8372-81 56 Citations |
| 1 | Cannabinoid-receptor-independent cell signalling by N-acylethanolamines. (Berdyshev EV, Schmid PC, Krebsbach RJ, Hillard CJ, Huang C, Chen N, Dong Z, Schmid HH) Biochem J 2001 Nov 15;360(Pt 1):67-75 72 Citations |
| 1 | Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress. (Go YM, Boo YC, Park H, Maland MC, Patel R, Pritchard KA Jr, Fujio Y, Walsh K, Darley-Usmar V, Jo H) J Appl Physiol (1985) 2001 Oct;91(4):1574-81 93 Citations |
| 1 | The perplexed and confused mutations affect distinct stages during the transition from proliferating to post-mitotic cells within the zebrafish retina. (Link BA, Kainz PM, Ryou T, Dowling JE) Dev Biol 2001 Aug 15;236(2):436-53 25 Citations |
| 1 | Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein. (Zhao YG, Gilmore R, Leone G, Coffey MC, Weber B, Lee PW) J Biol Chem 2001 Aug 31;276(35):32822-7 93 Citations |
| 1 | G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells. (Grewal JS, Luttrell LM, Raymond JR) J Biol Chem 2001 Jul 20;276(29):27335-44 46 Citations |
| 1 | Endothelin-1 induces serine phosphorylation of the adaptor protein p66Shc and its association with 14-3-3 protein in glomerular mesangial cells. (Foschi M, Franchi F, Han J, La Villa G, Sorokin A) J Biol Chem 2001 Jul 13;276(28):26640-7 41 Citations |
| 2 | Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). (Newman DK, Hamilton C, Newman PJ) Blood 2001 Apr 15;97(8):2351-7 118 Citations |
| 1 | Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells. (Sorokin A, Kozlowski P, Graves L, Philip A) J Biol Chem 2001 Jun 15;276(24):21521-8 65 Citations |
| 1 | Two-state allosteric behavior in a single-domain signaling protein. (Volkman BF, Lipson D, Wemmer DE, Kern D) Science 2001 Mar 23;291(5512):2429-33 559 Citations |
| 1 | Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death. (Weng LP, Gimm O, Kum JB, Smith WM, Zhou XP, Wynford-Thomas D, Leone G, Eng C) Hum Mol Genet 2001 Feb 01;10(3):251-8 83 Citations |
| 1 | Intracellular function in rehydrated lyophilized platelets. (Fischer TH, Merricks EP, Russell KE, Raymer RA, White GC, Bode AP, Nichols TC, Read MS) Br J Haematol 2000 Oct;111(1):167-74 31 Citations |
| 1 | CREB (cAMP response element binding protein) and C/EBPalpha (CCAAT/enhancer binding protein) are required for the superstimulation of phosphoenolpyruvate carboxykinase gene transcription by adenoviral E1a and cAMP. (Routes JM, Colton LA, Ryan S, Klemm DJ) Biochem J 2000 Dec 01;352 Pt 2(Pt 2):335-42 10 Citations |
| 1 | Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells. (Carpenter PA, Pavlovic S, Tso JY, Press OW, Gooley T, Yu XZ, Anasetti C) J Immunol 2000 Dec 01;165(11):6205-13 94 Citations |
| 1 | P2Y2 purinergic and M3 muscarinic acetylcholine receptors activate different phospholipase C-beta isoforms that are uniquely susceptible to protein kinase C-dependent phosphorylation and inactivation. (Strassheim D, Williams CL) J Biol Chem 2000 Dec 15;275(50):39767-72 53 Citations |
| 1 | The p38 pathway provides negative feedback for Ras proliferative signaling. (Chen G, Hitomi M, Han J, Stacey DW) J Biol Chem 2000 Dec 15;275(50):38973-80 162 Citations |
| 1 | Casein kinase I is anchored on axonemal doublet microtubules and regulates flagellar dynein phosphorylation and activity. (Yang P, Sale WS) J Biol Chem 2000 Jun 23;275(25):18905-12 103 Citations |
| 1 | Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. (Bruns CJ, Harbison MT, Davis DW, Portera CA, Tsan R, McConkey DJ, Evans DB, Abbruzzese JL, Hicklin DJ, Radinsky R) Clin Cancer Res 2000 May;6(5):1936-48 431 Citations |
| 1 | 5-HT(2A) receptors stimulate mitogen-activated protein kinase via H(2)O(2) generation in rat renal mesangial cells. (Greene EL, Houghton O, Collinsworth G, Garnovskaya MN, Nagai T, Sajjad T, Bheemanathini V, Grewal JS, Paul RV, Raymond JR) Am J Physiol Renal Physiol 2000 Apr;278(4):F650-8 85 Citations |
| 1 | 5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts. (Mukhin YV, Garnovskaya MN, Collinsworth G, Grewal JS, Pendergrass D, Nagai T, Pinckney S, Greene EL, Raymond JR) Biochem J 2000 Apr 01;347 Pt 1(Pt 1):61-7 69 Citations |
| 1 | Tyrosine phosphorylation and association of FcgammaRII and p72(Syk) are not limited to the FcgammaRII signalling pathway. (Pain S, Falet H, Saci A, Bachelot-Loza C, Rendu F) Cell Signal 2000 Mar;12(3):165-71 15 Citations |
| 1 | Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton. (Koukouritaki SB, Gravanis A, Stournaras C) Mol Med 1999 Nov;5(11):731-42 49 Citations |
| 1 | Structure of a transiently phosphorylated switch in bacterial signal transduction. (Kern D, Volkman BF, Luginbühl P, Nohaile MJ, Kustu S, Wemmer DE) Nature 1999 Dec 23-30;402(6764):894-8 180 Citations |
| 1 | Human intestinal epithelial cells express receptors for platelet-activating factor. (Merendino N, Dwinell MB, Varki N, Eckmann L, Kagnoff MF) Am J Physiol 1999 Oct;277(4):G810-8 24 Citations |
| 1 | A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. (Ghoshal N, Smiley JF, DeMaggio AJ, Hoekstra MF, Cochran EJ, Binder LI, Kuret J) Am J Pathol 1999 Oct;155(4):1163-72 132 Citations |
| 2 | Structural basis for recognition of phosphorylated high mannose oligosaccharides by the cation-dependent mannose 6-phosphate receptor. (Olson LJ, Zhang J, Lee YC, Dahms NM, Kim JJ) J Biol Chem 1999 Oct 15;274(42):29889-96 56 Citations |
| 1 | Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. (Heitmeier MR, Scarim AL, Corbett JA) J Biol Chem 1999 Oct 08;274(41):29266-73 67 Citations |
| 1 | Enhanced expression of the cytoskeleton-associated proteins paxillin and focal adhesion kinase in glomerular immune injury. (Koukouritaki SB, Tamizuddin A, Lianos EA) J Lab Clin Med 1999 Aug;134(2):173-9 12 Citations |
| 1 | In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor. (Sweeney WE, Futey L, Frost P, Avner ED) Kidney Int 1999 Aug;56(2):406-13 45 Citations |
| 1 | TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase. (Koukouritaki SB, Vardaki EA, Papakonstanti EA, Lianos E, Stournaras C, Emmanouel DS) Mol Med 1999 Jun;5(6):382-92 82 Citations |
| 1 | Calpain controls the balance between protein tyrosine kinase and tyrosine phosphatase activities during platelet activation. (Pain S, Monstero-Lastres A, Falet H, Brohard-Bohn B, Fraiz N, Bachelot-Loza C, Cano E, Rendu F) FEBS Lett 1999 Jun 18;453(1-2):119-23 7 Citations |
| 1 | A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. (Newton-Nash DK, Newman PJ) J Immunol 1999 Jul 15;163(2):682-8 145 Citations |
| 1 | PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction. (Garrett-Sinha LA, Su GH, Rao S, Kabak S, Hao Z, Clark MR, Simon MC) Immunity 1999 Apr;10(4):399-408 106 Citations |
| 1 | Glucocorticoid effect on human mesangial cell cytoskeletal proteins. (Koukouritaki SB, Lianos EA) J Lab Clin Med 1999 Apr;133(4):378-83 11 Citations |
| 1 | Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. (Chen G, Yuan SS, Liu W, Xu Y, Trujillo K, Song B, Cong F, Goff SP, Wu Y, Arlinghaus R, Baltimore D, Gasser PJ, Park MS, Sung P, Lee EY) J Biol Chem 1999 Apr 30;274(18):12748-52 244 Citations |
| 1 | Interaction of 14-3-3 with a nonphosphorylated protein ligand, exoenzyme S of Pseudomonas aeruginosa. (Masters SC, Pederson KJ, Zhang L, Barbieri JT, Fu H) Biochemistry 1999 Apr 20;38(16):5216-21 134 Citations |
| 1 | Arachidonate-induced tyrosine phosphorylation of epidermal growth factor receptor and Shc-Grb2-Sos association. (Dulin NO, Sorokin A, Douglas JG) Hypertension 1998 Dec;32(6):1089-93 34 Citations |
| 1 | Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. (Sweeney WE Jr, Avner ED) Am J Physiol 1998 Sep;275(3):F387-94 92 Citations |
| 1 | Insulin stimulates the tyrosine dephosphorylation of docking protein p130cas (Crk-associated substrate), promoting the switch of the adaptor protein crk from p130cas to newly phosphorylated insulin receptor substrate-1. (Sorokin A, Reed E) Biochem J 1998 Sep 15;334 ( Pt 3)(Pt 3):595-600 18 Citations |
| 1 | Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses. (Minichiello L, Casagranda F, Tatche RS, Stucky CL, Postigo A, Lewin GR, Davies AM, Klein R) Neuron 1998 Aug;21(2):335-45 166 Citations |
| 1 | Crk protein binds to PDGF receptor and insulin receptor substrate-1 with different modulating effects on PDGF- and insulin-dependent signaling pathways. (Sorokin A, Reed E, Nnkemere N, Dulin NO, Schlessinger J) Oncogene 1998 May 14;16(19):2425-34 17 Citations |
| 1 | A new class II rice chitinase, Rcht2, whose induction by fungal elicitor is abolished by protein phosphatase 1 and 2A inhibitor. (Kim CY, Gal SW, Choe MS, Jeong SY, Lee SI, Cheong YH, Lee SH, Choi YJ, Han CD, Kang KY, Cho MJ) Plant Mol Biol 1998 Jun;37(3):523-34 38 Citations |
| 1 | The neuropeptide Y/peptide YY Y1 receptor is coupled to MAP kinase via PKC and Ras in CHO cells. (Mannon PJ, Raymond JR) Biochem Biophys Res Commun 1998 May 08;246(1):91-4 29 Citations |
| 1 | Evidence for involvement of the proteasome complex (26S) and NFkappaB in IL-1beta-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells. (Kwon G, Corbett JA, Hauser S, Hill JR, Turk J, McDaniel ML) Diabetes 1998 Apr;47(4):583-91 77 Citations |
| 1 | The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa. (Feng H, Sandlow JI, Sandra A) Mol Reprod Dev 1998 Mar;49(3):317-26 48 Citations |
| 1 | SH2- and SH3-mediated interactions between focal adhesion kinase and Src. (Thomas JW, Ellis B, Boerner RJ, Knight WB, White GC 2nd, Schaller MD) J Biol Chem 1998 Jan 02;273(1):577-83 218 Citations |
| 1 | Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase. (Foschi M, Chari S, Dunn MJ, Sorokin A) EMBO J 1997 Nov 03;16(21):6439-51 143 Citations |
| 1 | Integrin-mediated activation of focal adhesion kinase is independent of focal adhesion formation or integrin activation. Studies with activated and inhibitory beta3 cytoplasmic domain mutants. (Lyman S, Gilmore A, Burridge K, Gidwitz S, White GC 2nd) J Biol Chem 1997 Sep 05;272(36):22538-47 72 Citations |
| 1 | Phosphocitrate inhibits a basic calcium phosphate and calcium pyrophosphate dihydrate crystal-induced mitogen-activated protein kinase cascade signal transduction pathway. (Nair D, Misra RP, Sallis JD, Cheung HS) J Biol Chem 1997 Jul 25;272(30):18920-5 70 Citations |
| 1 | Role of His243 in the phosphatase activity of EnvZ in Escherichia coli. (Skarphol K, Waukau J, Forst SA) J Bacteriol 1997 Feb;179(4):1413-6 34 Citations |
| 1 | Re-examination of the role of the periplasmic domain of EnvZ in sensing of osmolarity signals in Escherichia coli. (Leonardo MR, Forst S) Mol Microbiol 1996 Nov;22(3):405-13 38 Citations |
| 1 | Exploration of the effects of linker chain modifications on anti-HIV activities in a series of cosalane analogues. (Golebiewski WM, Keyes RF, Cushman M) Bioorg Med Chem 1996 Oct;4(10):1637-48 25 Citations |
| 1 | Cyclic AMP-dependent phosphodiesterase isozyme-specific potentiation by protein kinase C in hypertrophic cardiomyopathic hamster hearts. (Yu H, Cai JJ, Lee HC) Mol Pharmacol 1996 Sep;50(3):549-55 12 Citations |
| 1 | Multiple intracellular MAP kinase signaling cascades. (Bokemeyer D, Sorokin A, Dunn MJ) Kidney Int 1996 May;49(5):1187-98 172 Citations |
| 1 | Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. (Mohammadi M, Dikic I, Sorokin A, Burgess WH, Jaye M, Schlessinger J) Mol Cell Biol 1996 Mar;16(3):977-89 355 Citations |
| 1 | The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin. (Si-Tahar M, Renesto P, Falet H, Rendu F, Chignard M) Biochem J 1996 Jan 15;313 ( Pt 2)(Pt 2):401-8 34 Citations |
| 1 | Mutation of serine 90 to glutamic acid mimics phosphorylation of bovine prolactin. (Maciejewski PM, Peterson FC, Anderson PJ, Brooks CL) J Biol Chem 1995 Nov 17;270(46):27661-5 61 Citations |
| 1 | Activation of the EGF receptor by insertional mutations in its juxtamembrane regions. (Sorokin A) Oncogene 1995 Oct 19;11(8):1531-40 30 Citations |
| 1 | Agonist-induced desensitization and phosphorylation of human 5-HT1A receptor expressed in Sf9 insect cells. (Nebigil CG, Garnovskaya MN, Casañas SJ, Mulheron JG, Parker EM, Gettys TW, Raymond JR) Biochemistry 1995 Sep 19;34(37):11954-62 33 Citations |
| 1 | Molecular analysis of the two-component genes, ompR and envZ, in the symbiotic bacterium Xenorhabdus nematophilus. (Tabatabai N, Forst S) Mol Microbiol 1995 Aug;17(4):643-52 31 Citations |
| 1 | Genetic and carbon source regulation of phosphorylation of Sip1p, a Snf1p-associated protein involved in carbon response in Saccharomyces cerevisiae. (Long RM, Hopper JE) Yeast 1995 Mar;11(3):233-46 3 Citations |
| 1 | Translocation and activation of protein kinase C by the plasma cell tumor-promoting alkane pristane. (Janz S, Gawrisch K, Lester DS) Cancer Res 1995 Feb 01;55(3):518-24 12 Citations |
| 1 | L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway. (Misra RP, Bonni A, Miranti CK, Rivera VM, Sheng M, Greenberg ME) J Biol Chem 1994 Oct 14;269(41):25483-93 151 Citations |
| 1 | Protein kinase A induces phosphorylation of the human 5-HT1A receptor and augments its desensitization by protein kinase C in CHO-K1 cells. (Raymond JR, Olsen CL) Biochemistry 1994 Sep 20;33(37):11264-9 26 Citations |
| 1 | Aluminum-induced DNA synthesis in osteoblasts: mediation by a G-protein coupled cation sensing mechanism. (Quarles LD, Hartle JE 2nd, Middleton JP, Zhang J, Arthur JM, Raymond JR) J Cell Biochem 1994 Sep;56(1):106-17 93 Citations |
| 1 | Calcium mobilisation controls tyrosine protein phosphorylation independently of the activation of protein kinase C in human platelets. (Falet H, Rendu F) FEBS Lett 1994 May 23;345(1):87-91 20 Citations |
| 1 | Identification of the site of phosphorylation on the osmosensor, EnvZ, of Escherichia coli. (Roberts DL, Bennett DW, Forst SA) J Biol Chem 1994 Mar 25;269(12):8728-33 49 Citations |
| 1 | Sphingosine-mediated phosphatidylinositol metabolism and calcium mobilization. (Chao CP, Laulederkind SJ, Ballou LR) J Biol Chem 1994 Feb 25;269(8):5849-56 88 Citations |
| 1 | NPXY motif in the insulin-like growth factor-I receptor is required for efficient ligand-mediated receptor internalization and biological signaling. (Hsu D, Knudson PE, Zapf A, Rolband GC, Olefsky JM) Endocrinology 1994 Feb;134(2):744-50 50 Citations |
| 1 | Identification of a phosphorylation site and functional analysis of conserved aspartic acid residues of OmpR, a transcriptional activator for ompF and ompC in Escherichia coli. (Delgado J, Forst S, Harlocker S, Inouye M) Mol Microbiol 1993 Dec;10(5):1037-47 94 Citations |
| 1 | A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. (Rivera VM, Miranti CK, Misra RP, Ginty DD, Chen RH, Blenis J, Greenberg ME) Mol Cell Biol 1993 Oct;13(10):6260-73 246 Citations |
| 1 | Cytoskeletal interactions of Rap1b in platelets. (White GC 2nd, Crawford N, Fischer TH) Adv Exp Med Biol 1993;344:187-94 11 Citations |
| 1 | Phosphorylation-independent regulation of cardiac IK by guanine nucleotides and isoproterenol. (Freeman LC, Kwok WM, Kass RS) Am J Physiol 1992 Apr;262(4 Pt 2):H1298-302 18 Citations |
| 1 | Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism. (Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ) J Biol Chem 1992 Mar 05;267(7):4740-6 128 Citations |
| 1 | Molecular analysis of the signaling pathway between EnvZ and OmpR in Escherichia coli. (Waukau J, Forst S) J Bacteriol 1992 Mar;174(5):1522-7 38 Citations |
| 1 | The serum response factor is extensively modified by phosphorylation following its synthesis in serum-stimulated fibroblasts. (Misra RP, Rivera VM, Wang JM, Fan PD, Greenberg ME) Mol Cell Biol 1991 Sep;11(9):4545-54 87 Citations |
| 1 | Protein kinase C induces phosphorylation and desensitization of the human 5-HT1A receptor. (Raymond JR) J Biol Chem 1991 Aug 05;266(22):14747-53 111 Citations |
| 1 | The localization of the cAMP-dependent protein kinase phosphorylation site in the platelet rat protein, rap 1B. (Fischer TH, Collins JH, Gatling MN, White GC 2nd) FEBS Lett 1991 Jun 03;283(2):173-6 9 Citations |
| 1 | Ca2(+)-enhanced phosphorylation of a chimeric protein kinase involved with bacterial signal transduction. (Rampersaud A, Utsumi R, Delgado J, Forst SA, Inouye M) J Biol Chem 1991 Apr 25;266(12):7633-7 32 Citations |
| 1 | GAL11 (SPT13), a transcriptional regulator of diverse yeast genes, affects the phosphorylation state of GAL4, a highly specific transcriptional activator. (Long RM, Mylin LM, Hopper JE) Mol Cell Biol 1991 Apr;11(4):2311-4 23 Citations |
| 1 | 5-HT1A and histamine H1 receptors in HeLa cells stimulate phosphoinositide hydrolysis and phosphate uptake via distinct G protein pools. (Raymond JR, Albers FJ, Middleton JP, Lefkowitz RJ, Caron MG, Obeid LM, Dennis VW) J Biol Chem 1991 Jan 05;266(1):372-9 65 Citations |
| 1 | Epidermal growth factor induces tyrosine phosphorylation of epidermal growth factor receptors not occupied with ligand in intact A431 cells. (Sorokin AB, Reshetnikova GF, Kudryavtseva NV, Nikolsky NN) FEBS Lett 1990 Jul 30;268(1):121-4 1 Citation |
| 1 | In vivo phosphorylation of OmpR, the transcription activator of the ompF and ompC genes in Escherichia coli. (Forst S, Delgado J, Rampersaud A, Inouye M) J Bacteriol 1990 Jun;172(6):3473-7 72 Citations |
| 1 | Characterization of the platelet-derived growth factor beta-receptor kinase activity by use of synthetic peptides. (Rönnstrand L, Sorokin A, Engström U, Heldin CH) Biochem Biophys Res Commun 1990 Mar 30;167(3):1333-40 4 Citations |
| 1 | Thrombolamban, the 22-kDa platelet substrate of cyclic AMP-dependent protein kinase, is immunologically homologous with the Ras family of GTP-binding proteins. (White TE, Lacal JC, Reep B, Fischer TH, Lapetina EG, White GC 2nd) Proc Natl Acad Sci U S A 1990 Jan;87(2):758-62 32 Citations |
| 1 | [The ligand-dependent phosphorylation of epidermal growth factor receptors and the production of a secreted form of the receptor by cell strains of A-431 epidermoid carcinoma]. (Sorokin AB, Gudkova DA, Kudriavtseva NV, Nikol'skiĭ NN) Tsitologiia 1990;32(10):1026-30 |
| 1 | Cyclic AMP-dependent protein kinase does not increase calcium transport in platelet microsomes. (White GC 2nd, Barton DW, White TE, Fischer TH) Thromb Res 1989 Dec 01;56(5):575-81 7 Citations |
| 1 | Phosphorylation of OmpR by the osmosensor EnvZ modulates expression of the ompF and ompC genes in Escherichia coli. (Forst S, Delgado J, Inouye M) Proc Natl Acad Sci U S A 1989 Aug;86(16):6052-6 226 Citations |
| 1 | [Demonstration of an intact complex of epidermal growth factor and its receptor in the endosomes of A-431 cells]. (Kornilova ES, Bobrova IF, Nesterov AM, Nikol'skiĭ NN, Sorokin AB) Tsitologiia 1988 Mar;30(3):291-8 2 Citations |
| 1 | Partial purification and characterization of thrombolamban, a 22,000 dalton cAMP-dependent protein kinase substrate in platelets. (Fischer TH, White GC 2nd) Biochem Biophys Res Commun 1987 Dec 16;149(2):700-6 38 Citations |
| 1 | [Effect of dansylcadaverine on the epidermal growth factor-stimulated phosphorylation of uridine]. (Nesterov AM, Vinogradova NA, Kudriavtseva NV, Sorkin AD, Sorokin AB) Tsitologiia 1987 Sep;29(9):1020-6 |
| 1 | [Comparison of the effect of the epidermal growth factor (EGF) and its cyanogen bromide derivative on EGF receptor phosphorylation and uridine uptake in a cell culture]. (Nesterov AM, Sorokin AB, Okulova AN, Nikol'skiĭ NN) Tsitologiia 1987 Aug;29(8):911-6 |
| 1 | Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients. (Maxwell SA, Kurzrock R, Parsons SJ, Talpaz M, Gallick GE, Kloetzer WS, Arlinghaus RB, Kouttab NM, Keating MJ, Gutterman JU) Cancer Res 1987 Mar 15;47(6):1731-9 67 Citations |
| 1 | [Amine inhibition of serum-induced DNA synthesis in 3T3 and 3T6 cell cultures]. (Nikol'skiĭ NN, Barkan RS, Bogdanova NP, Vinogradova NA, Sorokin AB) Tsitologiia 1985 Apr;27(4):451-7 |
| 1 | The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity. (Kloetzer W, Kurzrock R, Smith L, Talpaz M, Spiller M, Gutterman J, Arlinghaus R) Virology 1985 Jan 30;140(2):230-8 172 Citations |
| 1 | [Mathematical analysis and experimental study of uridine transport and phosphorylation in 3T6 cells]. (Sorkin AD, Sorokin AB) Tsitologiia 1983 Jul;25(7):784-92 |
| 1 | Differential histone phosphorylation during Drosophila development. (Blumenfeld M, Billings PC, Orf JW, Pan CG, Palmer DK, Snyder LA) Results Probl Cell Differ 1980;11:45-8 1 Citation |
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