| 2 | Physiological and Molecular Implications of Angiotensinergic Signaling in the Brainstem. (Ghobrial M, Gomez RA, Grobe JL, Sigmund CD, Nakagawa P) Endocrinology 2025 Sep 08;166(10) 1 Citation |
| 3 | Role of the Renin-Angiotensin System in Blood Pressure Regulation in Smooth Muscle-Specific Cullin-3 Deficient Mice. (Golosova D, Kumar G, Chaihongsa N, Reho JJ, Lu KT, Brozoski DT, Wackman KK, Lawton SBR, Muskus PC, Lin BL, Grobe JL, Nakagawa P, Sigmund CD) Hypertension 2025 Jul;82(7):1208-1220 1 Citation |
| 4 | Definitive Evidence for the Identification and Function of Renin-Expressing Cholinergic Neurons in the Nucleus Ambiguus. (Fekete ÉM, Gomez J, Ghobrial M, Kaminski K, Muskus PC, Boychuk CR, Hantke Guixa A, Vazirabad I, Xie M, Ganiyu A, Golosova D, Mathieu NM, Wang YB, Lu KT, Wackman KK, Brozoski DT, Mouradian GC, Hodges MR, Segar JL, Grobe JL, Sigmund CD, Nakagawa P) Hypertension 2025 Feb;82(2):282-292 6 Citations |
| 2 | Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model. (Dowell J, Bice Z, Yan K, Konduri GG) Physiol Rep 2024 Jan;12(1):e15895 3 Citations |
| 1 | Appraising the Preclinical Evidence of the Role of the Renin-Angiotensin-Aldosterone System in Antenatal Programming of Maternal and Offspring Cardiovascular Health Across the Life Course: Moving the Field Forward: A Scientific Statement From the American Heart Association. (Alexander BT, South AM, August P, Bertagnolli M, Ferranti EP, Grobe JL, Jones EJ, Loria AS, Safdar B, Sequeira-Lopez MLS, American Heart Association Council on the Kidney in Cardiovascular Disease; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; Council on Hypertension; and Council on Lifestyle and Cardiometabolic Health) Hypertension 2023 May;80(5):e75-e89 28 Citations |
| 2 | Divergent roles of angiotensin II upon the immediate and sustained increases of renal blood flow following unilateral nephrectomy. (Shimada S, Yang C, Kurth T, Cowley AW Jr) Am J Physiol Renal Physiol 2022 May 01;322(5):F473-F485 8 Citations |
| 2 | Studies of salt and stress sensitivity on arterial pressure in renin-b deficient mice. (Nakagawa P, Gomez J, Lu KT, Grobe JL, Sigmund CD) PLoS One 2021;16(7):e0250807 3 Citations |
| 1 | Activation of the Central Renin-Angiotensin System Causes Local Cerebrovascular Dysfunction. (De Silva TM, Modrick ML, Grobe JL, Faraci FM) Stroke 2021 Jul;52(7):2404-2413 17 Citations |
| 3 | β-Arrestin-Biased Agonist Targeting the Brain AT1R (Angiotensin II Type 1 Receptor) Increases Aversion to Saline and Lowers Blood Pressure in Deoxycorticosterone Acetate-Salt Hypertension. (Zanaty M, Seara FAC, Nakagawa P, Deng G, Mathieu NM, Balapattabi K, Karnik SS, Grobe JL, Sigmund CD) Hypertension 2021 Feb;77(2):420-431 22 Citations |
| 1 | Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension. (Shawky NM, Patil CN, Dalmasso C, Maranon RO, Romero DG, Drummond H, Reckelhoff JF) Hypertension 2020 Sep;76(3):943-952 12 Citations |
| 3 | Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-Induced Organ Damage. (Nakagawa P, Nair AR, Agbor LN, Gomez J, Wu J, Zhang SY, Lu KT, Morgan DA, Rahmouni K, Grobe JL, Sigmund CD) Hypertension 2020 Aug;76(2):468-477 10 Citations |
| 2 | A colorful view of the brain renin-angiotensin system. (Sigmund CD, Grobe JL) Hypertens Res 2020 Apr;43(4):357-359 10 Citations |
| 2 | The Renin-Angiotensin System in the Central Nervous System and Its Role in Blood Pressure Regulation. (Nakagawa P, Gomez J, Grobe JL, Sigmund CD) Curr Hypertens Rep 2020 Jan 10;22(1):7 83 Citations |
| 1 | Relationship between the renin-angiotensin-aldosterone system and renal Kir5.1 channels. (Manis AD, Palygin O, Khedr S, Levchenko V, Hodges MR, Staruschenko A) Clin Sci (Lond) 2019 Dec 20;133(24):2449-2461 17 Citations |
| 1 | Progression of diabetic kidney disease in T2DN rats. (Palygin O, Spires D, Levchenko V, Bohovyk R, Fedoriuk M, Klemens CA, Sykes O, Bukowy JD, Cowley AW Jr, Lazar J, Ilatovskaya DV, Staruschenko A) Am J Physiol Renal Physiol 2019 Dec 01;317(6):F1450-F1461 50 Citations |
| 1 | The renin-angiotensin system in the arcuate nucleus controls resting metabolic rate. (Deng G, Grobe JL) Curr Opin Nephrol Hypertens 2019 Mar;28(2):120-127 15 Citations |
| 1 | Interference With Endothelial PPAR (Peroxisome Proliferator-Activated Receptor)-γ Causes Accelerated Cerebral Vascular Dysfunction in Response to Endogenous Renin-Angiotensin System Activation. (Nair AR, Agbor LN, Mukohda M, Liu X, Hu C, Wu J, Sigmund CD) Hypertension 2018 Nov;72(5):1227-1235 20 Citations |
| 1 | Hyperfiltration-mediated Injury in the Remaining Kidney of a Transplant Donor. (Srivastava T, Hariharan S, Alon US, McCarthy ET, Sharma R, El-Meanawy A, Savin VJ, Sharma M) Transplantation 2018 Oct;102(10):1624-1635 54 Citations |
| 1 | Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system. (Peng H, Jensen DD, Li W, Sullivan MN, Buller SA, Worker CJ, Cooper SG, Zheng S, Earley S, Sigmund CD, Feng Y) Am J Physiol Heart Circ Physiol 2018 Mar 01;314(3):H580-H592 18 Citations |
| 1 | Hyperkalemia Associated with Renin-Angiotensin-Aldosterone System Inhibition in Patients with Heart Failure; Underexplored and Overrated? (Koratala A, Aboud H, Kazory A) Nephron 2018;138(3):220-221 1 Citation |
| 1 | Cardiovascular and Metabolic Consequences of Testosterone Supplements in Young and Old Male Spontaneously Hypertensive Rats: Implications for Testosterone Supplements in Men. (Dalmasso C, Patil CN, Yanes Cardozo LL, Romero DG, Maranon RO) J Am Heart Assoc 2017 Oct 17;6(10) 25 Citations |
| 2 | Potential mechanisms of hypothalamic renin-angiotensin system activation by leptin and DOCA-salt for the control of resting metabolism. (Sapouckey SA, Deng G, Sigmund CD, Grobe JL) Physiol Genomics 2017 Dec 01;49(12):722-732 23 Citations |
| 3 | Selective Deletion of Renin-b in the Brain Alters Drinking and Metabolism. (Shinohara K, Nakagawa P, Gomez J, Morgan DA, Littlejohn NK, Folchert MD, Weidemann BJ, Liu X, Walsh SA, Ponto LL, Rahmouni K, Grobe JL, Sigmund CD) Hypertension 2017 Nov;70(5):990-997 19 Citations |
| 1 | Genetic Interference With Endothelial PPAR-γ (Peroxisome Proliferator-Activated Receptor-γ) Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7. (De Silva TM, Hu C, Kinzenbaw DA, Modrick ML, Sigmund CD, Faraci FM) Hypertension 2017 Sep;70(3):559-565 17 Citations |
| 2 | How Is the Brain Renin-Angiotensin System Regulated? (Nakagawa P, Sigmund CD) Hypertension 2017 Jul;70(1):10-18 68 Citations |
| 1 | Comprehensive Assessments of Energy Balance in Mice. (Grobe JL) Methods Mol Biol 2017;1614:123-146 44 Citations |
| 2 | Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice. (Agassandian K, Grobe JL, Liu X, Agassandian M, Thompson AP, Sigmund CD, Cassell MD) Am J Physiol Regul Integr Comp Physiol 2017 Jun 01;312(6):R973-R981 14 Citations |
| 1 | No Brain Renin-Angiotensin System: Déjà vu All Over Again? (Sigmund CD, Diz DI, Chappell MC) Hypertension 2017 Jun;69(6):1007-1010 34 Citations |
| 1 | Ovine uterine space restriction causes dysregulation of the renin-angiotensin system in fetal kidneys. (Kranch-Shorthouse RA, Bauer AS, Magness RR, Lopez GE, Segar JL, Blohowiak SE, Kling PJ) Biol Reprod 2017 Jan 01;96(1):211-220 2 Citations |
| 2 | Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension. (Shinohara K, Liu X, Morgan DA, Davis DR, Sequeira-Lopez ML, Cassell MD, Grobe JL, Rahmouni K, Sigmund CD) Hypertension 2016 Dec;68(6):1385-1392 46 Citations |
| 2 | Suppression of Resting Metabolism by the Angiotensin AT2 Receptor. (Littlejohn NK, Keen HL, Weidemann BJ, Claflin KE, Tobin KV, Markan KR, Park S, Naber MC, Gourronc FA, Pearson NA, Liu X, Morgan DA, Klingelhutz AJ, Potthoff MJ, Rahmouni K, Sigmund CD, Grobe JL) Cell Rep 2016 Aug 09;16(6):1548-1560 39 Citations |
| 1 | Neonatal growth restriction-related leptin deficiency enhances leptin-triggered sympathetic activation and central angiotensin II receptor-dependent stress-evoked hypertension. (Peotta V, Rahmouni K, Segar JL, Morgan DA, Pitz KM, Rice OM, Roghair RD) Pediatr Res 2016 Aug;80(2):244-51 5 Citations |
| 1 | Opposing tissue-specific roles of angiotensin in the pathogenesis of obesity, and implications for obesity-related hypertension. (Littlejohn NK, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2015 Dec 15;309(12):R1463-73 28 Citations |
| 1 | The Evaluation and Therapeutic Management of Hypertension in the Transplant Patient. (Thomas B, Weir MR) Curr Cardiol Rep 2015 Nov;17(11):95 12 Citations |
| 1 | Vascular versus tubular renin: role in kidney development. (Sequeira-Lopez ML, Nagalakshmi VK, Li M, Sigmund CD, Gomez RA) Am J Physiol Regul Integr Comp Physiol 2015 Sep 15;309(6):R650-7 32 Citations |
| 2 | Dietary Sodium Suppresses Digestive Efficiency via the Renin-Angiotensin System. (Weidemann BJ, Voong S, Morales-Santiago FI, Kahn MZ, Ni J, Littlejohn NK, Claflin KE, Burnett CM, Pearson NA, Lutter ML, Grobe JL) Sci Rep 2015 Jun 11;5:11123 28 Citations |
| 1 | Control of energy balance by the brain renin-angiotensin system. (Claflin KE, Grobe JL) Curr Hypertens Rep 2015 May;17(5):38 31 Citations |
| 1 | Molecular mechanisms regulating vascular tone by peroxisome proliferator activated receptor gamma. (Ketsawatsomkron P, Sigmund CD) Curr Opin Nephrol Hypertens 2015 Mar;24(2):123-30 26 Citations |
| 2 | Mechanisms of brain renin angiotensin system-induced drinking and blood pressure: importance of the subfornical organ. (Coble JP, Grobe JL, Johnson AK, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2015 Feb 15;308(4):R238-49 86 Citations |
| 1 | Renin knockout rat: control of adrenal aldosterone and corticosterone synthesis in vitro and adrenal gene expression. (Raff H, Gehrand A, Bruder ED, Hoffman MJ, Engeland WC, Moreno C) Am J Physiol Regul Integr Comp Physiol 2015 Jan 01;308(1):R73-7 6 Citations |
| 2 | Another reason to eat your greens: cardiopulmonary protection by dietary delivery of angiotensin-converting enzyme-2 and angiotensin-(1-7) made in plants. (Grobe JL, Sigmund CD) Hypertension 2014 Dec;64(6):1182-3 3 Citations |
| 2 | Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. (Carrillo-Sepulveda MA, Keen HL, Davis DR, Grobe JL, Sigmund CD) PLoS One 2014;9(8):e103786 12 Citations |
| 2 | Activation of the renin-angiotensin system, specifically in the subfornical organ is sufficient to induce fluid intake. (Coble JP, Cassell MD, Davis DR, Grobe JL, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2014 Aug 15;307(4):R376-86 24 Citations |
| 1 | Pathophysiology, diagnosis, and treatment of mineralocorticoid disorders. (Magill SB) Compr Physiol 2014 Jul;4(3):1083-119 11 Citations |
| 1 | Renin-angiotensin system and fibrosis in non-alcoholic fatty liver disease. (Goh GB, Pagadala MR, Dasarathy J, Unalp-Arida A, Sargent R, Hawkins C, Sourianarayanane A, Khiyami A, Yerian L, Pai R, McCullough AJ, Dasarathy S) Liver Int 2015 Mar;35(3):979-85 111 Citations |
| 2 | The vascular renin-angiotensin system contributes to blunted vasodilation induced by transient high pressure in human adipose microvessels. (Durand MJ, Phillips SA, Widlansky ME, Otterson MF, Gutterman DD) Am J Physiol Heart Circ Physiol 2014 Jul 01;307(1):H25-32 20 Citations |
| 2 | Activity of protein kinase C-α within the subfornical organ is necessary for fluid intake in response to brain angiotensin. (Coble JP, Johnson RF, Cassell MD, Johnson AK, Grobe JL, Sigmund CD) Hypertension 2014 Jul;64(1):141-8 17 Citations |
| 2 | Hypertension in mice with transgenic activation of the brain renin-angiotensin system is vasopressin dependent. (Littlejohn NK, Siel RB Jr, Ketsawatsomkron P, Pelham CJ, Pearson NA, Hilzendeger AM, Buehrer BA, Weidemann BJ, Li H, Davis DR, Thompson AP, Liu X, Cassell MD, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2013 May 15;304(10):R818-28 61 Citations |
| 1 | A clinical link between peroxisome proliferator-activated receptor γ and the renin-angiotensin system. (Sigmund CD) Arterioscler Thromb Vasc Biol 2013 Apr;33(4):676-8 12 Citations |
| 1 | Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. (Beyer AM, Raffai G, Weinberg B, Fredrich K, Lombard JH) Hypertension 2012 Aug;60(2):404-10 27 Citations |
| 2 | A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. (Hilzendeger AM, Morgan DA, Brooks L, Dellsperger D, Liu X, Grobe JL, Rahmouni K, Sigmund CD, Mark AL) Am J Physiol Heart Circ Physiol 2012 Jul 15;303(2):H197-206 102 Citations |
| 2 | Metabolic rate regulation by the renin-angiotensin system: brain vs. body. (Grobe JL, Rahmouni K, Liu X, Sigmund CD) Pflugers Arch 2013 Jan;465(1):167-75 29 Citations |
| 1 | Enzymatic processing of angiotensin peptides by human glomerular endothelial cells. (Velez JC, Ierardi JL, Bland AM, Morinelli TA, Arthur JM, Raymond JR, Janech MG) Am J Physiol Renal Physiol 2012 Jun 15;302(12):F1583-94 39 Citations |
| 1 | Evolution of treatment for diabetic nephropathy: historical progression from RAAS inhibition and onward. (Blumenthal SS) Postgrad Med 2011 Nov;123(6):166-79 10 Citations |
| 1 | Editorial focus: A fat contribution to RAS activation and blood pressure control: evidence from angiotensinogen conditional null mice. Focus on: "Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice.". (Grobe JL, Rahmouni K) Am J Physiol Regul Integr Comp Physiol 2012 Jan 15;302(2):R242-3 |
| 1 | Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system. (Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2012 Feb 01;302(3):R313-20 17 Citations |
| 1 | Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle. (Mital S, Chung WK, Colan SD, Sleeper LA, Manlhiot C, Arrington CB, Cnota JF, Graham EM, Mitchell ME, Goldmuntz E, Li JS, Levine JC, Lee TM, Margossian R, Hsu DT, Pediatric Heart Network Investigators) Circulation 2011 May 31;123(21):2353-62 63 Citations |
| 2 | Angiotensinergic signaling in the brain mediates metabolic effects of deoxycorticosterone (DOCA)-salt in C57 mice. (Grobe JL, Buehrer BA, Hilzendeger AM, Liu X, Davis DR, Xu D, Sigmund CD) Hypertension 2011 Mar;57(3):600-7 89 Citations |
| 2 | Creation and characterization of a renin knockout rat. (Moreno C, Hoffman M, Stodola TJ, Didier DN, Lazar J, Geurts AM, North PE, Jacob HJ, Greene AS) Hypertension 2011 Mar;57(3):614-9 57 Citations |
| 2 | Neuron- or glial-specific ablation of secreted renin does not affect renal renin, baseline arterial pressure, or metabolism. (Xu D, Borges GR, Davis DR, Agassandian K, Sequeira Lopez ML, Gomez RA, Cassell MD, Grobe JL, Sigmund CD) Physiol Genomics 2011 Mar 29;43(6):286-94 20 Citations |
| 1 | Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. (Cowley AW Jr) J Appl Physiol (1985) 2010 Dec;109(6):2009-10 |
| 2 | The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance. (Grobe JL, Grobe CL, Beltz TG, Westphal SG, Morgan DA, Xu D, de Lange WJ, Li H, Sakai K, Thedens DR, Cassis LA, Rahmouni K, Mark AL, Johnson AK, Sigmund CD) Cell Metab 2010 Nov 03;12(5):431-42 137 Citations |
| 1 | Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. (Durand MJ, Moreno C, Greene AS, Lombard JH) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1865-74 21 Citations |
| 1 | Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generation. (Yaghini FA, Song CY, Lavrentyev EN, Ghafoor HU, Fang XR, Estes AM, Campbell WB, Malik KU) Hypertension 2010 Jun;55(6):1461-7 81 Citations |
| 2 | Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin. (Xu D, Borges GR, Grobe JL, Pelham CJ, Yang B, Sigmund CD) Hypertension 2009 Dec;54(6):1240-7 36 Citations |
| 1 | 17beta-Estradiol modulates local cardiac renin-angiotensin system to prevent cardiac remodeling in the DOCA-salt model of hypertension in rats. (Shenoy V, Grobe JL, Qi Y, Ferreira AJ, Fraga-Silva RA, Collamat G, Bruce E, Katovich MJ) Peptides 2009 Dec;30(12):2309-15 40 Citations |
| 1 | Angiotensin-(1-7) as an antihypertensive, antifibrotic target. (Katovich MJ, Grobe JL, Raizada MK) Curr Hypertens Rep 2008 Jun;10(3):227-32 35 Citations |
| 2 | An intracellular renin-angiotensin system in neurons: fact, hypothesis, or fantasy. (Grobe JL, Xu D, Sigmund CD) Physiology (Bethesda) 2008 Aug;23:187-93 169 Citations |
| 1 | Influence of early life events on health and diseases. (Robillard JE, Segar JL) Trans Am Clin Climatol Assoc 2006;117:313-9; discussion 319-20 12 Citations |
| 1 | Is peroxisome proliferator-activated receptor-gamma a new "pal" of renin? (Weatherford ET, Itani H, Keen HL, Sigmund CD) Hypertension 2007 Nov;50(5):844-6 9 Citations |
| 1 | Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. (Velez JC, Bland AM, Arthur JM, Raymond JR, Janech MG) Am J Physiol Renal Physiol 2007 Jul;293(1):F398-407 86 Citations |
| 1 | Genetic basis of hypertension: revisiting angiotensinogen. (Dickson ME, Sigmund CD) Hypertension 2006 Jul;48(1):14-20 119 Citations |
| 1 | RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney. (Sachetelli S, Liu Q, Zhang SL, Liu F, Hsieh TJ, Brezniceanu ML, Guo DF, Filep JG, Ingelfinger JR, Sigmund CD, Hamet P, Chan JS) Kidney Int 2006 Mar;69(6):1016-23 115 Citations |
| 1 | Glial-specific ablation of angiotensinogen lowers arterial pressure in renin and angiotensinogen transgenic mice. (Sherrod M, Davis DR, Zhou X, Cassell MD, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2005 Dec;289(6):R1763-9 30 Citations |
| 1 | Molecular evidence of tissue renin-angiotensin systems: a focus on the brain. (Sakai K, Sigmund CD) Curr Hypertens Rep 2005 Apr;7(2):135-40 40 Citations |
| 1 | Angiotensin-converting enzyme 2 as a novel target for gene therapy for hypertension. (Katovich MJ, Grobe JL, Huentelman M, Raizada MK) Exp Physiol 2005 May;90(3):299-305 31 Citations |
| 1 | Effects of cortisol on cardiac myocytes and on expression of cardiac genes in fetal sheep. (Lumbers ER, Boyce AC, Joulianos G, Kumarasamy V, Barner E, Segar JL, Burrell JH) Am J Physiol Regul Integr Comp Physiol 2005 Mar;288(3):R567-74 75 Citations |
| 1 | Transgenic mice for studies of the renin-angiotensin system in hypertension. (Lavoie JL, Bianco RA, Sakai K, Keen HL, Ryan MJ, Sigmund CD) Acta Physiol Scand 2004 Aug;181(4):571-7 24 Citations |
| 1 | Increased blood pressure in transgenic mice expressing both human renin and angiotensinogen in the renal proximal tubule. (Lavoie JL, Lake-Bruse KD, Sigmund CD) Am J Physiol Renal Physiol 2004 May;286(5):F965-71 101 Citations |
| 1 | Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice. (Ma X, Sigmund CD, Hingtgen SD, Tian X, Davisson RL, Abboud FM, Chapleau MW) Hypertension 2004 Feb;43(2):312-6 26 Citations |
| 1 | Minireview: overview of the renin-angiotensin system--an endocrine and paracrine system. (Lavoie JL, Sigmund CD) Endocrinology 2003 Jun;144(6):2179-83 514 Citations |
| 1 | Cerebral arteriolar structure in mice overexpressing human renin and angiotensinogen. (Baumbach GL, Sigmund CD, Faraci FM) Hypertension 2003 Jan;41(1):50-5 91 Citations |
| 1 | Angiotensin mutant mice: a focus on the brain renin-angiotensin system. (Morimoto S, Sigmund CD) Neuropeptides 2002;36(2-3):194-200 32 Citations |
| 1 | Regulation of renin expression and blood pressure by vitamin D(3). (Sigmund CD) J Clin Invest 2002 Jul;110(2):155-6 63 Citations |
| 1 | Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. (Morimoto S, Cassell MD, Sigmund CD) J Biol Chem 2002 Sep 06;277(36):33235-41 105 Citations |
| 1 | The brain renin-angiotensin system in transgenic mice carrying a highly regulated human renin transgene. (Morimoto S, Cassell MD, Sigmund CD) Circ Res 2002 Jan 11;90(1):80-6 43 Citations |
| 1 | Genetic manipulation of the renin-angiotensin system in the kidney. (Sigmund CD) Acta Physiol Scand 2001 Sep;173(1):67-73 8 Citations |
| 1 | Genetic manipulation of the renin-angiotensin system: targeted expression of the renin-angiotensin system in the kidney. (Sigmund CD) Am J Hypertens 2001 Jun;14(6 Pt 2):33S-37S 17 Citations |
| 1 | Physiological insights from genetic manipulation of the renin-angiotensin system. (Stec DE, Sigmund CD) News Physiol Sci 2001 Apr;16:80-4 7 Citations |
| 1 | Glucocorticoid modulation of cardiovascular and autonomic function in preterm lambs: role of ANG II. (Segar JL, Bedell KA, Smith OJ) Am J Physiol Regul Integr Comp Physiol 2001 Mar;280(3):R646-54 36 Citations |
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| 1 | Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways. (Lake-Bruse KD, Sigmund CD) Curr Hypertens Rep 2000 Apr;2(2):211-6 9 Citations |
| 1 | Understanding hypertension through genetic manipulation in mice. (Cvetkovic B, Sigmund CD) Kidney Int 2000 Mar;57(3):863-74 39 Citations |
| 1 | Transgenic models as tools for studying the regulation of human renin expression. (Sinn PL, Sigmund CD) Regul Pept 2000 Jan 29;86(1-3):77-82 9 Citations |
| 1 | The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes. (Davisson RL, Yang G, Beltz TG, Cassell MD, Johnson AK, Sigmund CD) Circ Res 1998 Nov 16;83(10):1047-58 131 Citations |
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| 1 | Regulation of sodium metabolism and extracellular fluid volume during development. (Robillard JE, Segar JL, Smith FG, Jose PA) Clin Perinatol 1992 Mar;19(1):15-31 23 Citations |
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