Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Dorothee Weihrauch DVM, PhD

Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Research

Member of the Cardiovascular Center


Publications

  • Corrigendum to "Red/near infrared light stimulates release of an endothelium dependent vasodilator and rescues vascular dysfunction in a diabetes model" [Free Radic. Biol. Med. 113:157-164]. (Keszler A, Lindemer B, Weihrauch D, Jones D, Hogg N, Lohr NL) Free Radic Biol Med 2019 Feb 01;131:443 PMID: 30581102 12/26/2018    
  • Wavelength-dependence of vasodilation and NO release from S-nitrosothiols and dinitrosyl iron complexes by far red/near infrared light. (Keszler A, Lindemer B, Hogg N, Weihrauch D, Lohr NL) Arch Biochem Biophys 2018 Jul 01;649:47-52 PMID: 29752896 05/13/2018    
  • Red/near infrared light stimulates release of an endothelium dependent vasodilator and rescues vascular dysfunction in a diabetes model. (Keszler A, Lindemer B, Weihrauch D, Jones D, Hogg N, Lohr NL) Free Radic Biol Med 2017 12;113:157-164 PMID: 28935419 PMCID: PMC5699925 09/25/2017       4 Citations
  • Detection of TRPV4 channel current-like activity in Fawn Hooded hypertensive (FHH) rat cerebral arterial muscle cells. (Gebremedhin D, Zhang DX, Weihrauch D, Uche NN, Harder DR) PLoS One 2017;12(5):e0176796 PMID: 28472069 PMCID: PMC5417564 05/05/2017    
  • Lipid emulsion enhances cardiac performance after ischemia-reperfusion in isolated hearts from summer-active arctic ground squirrels. (Salzman MM, Cheng Q, Deklotz RJ, Dulai GK, Douglas HF, Dikalova AE, Weihrauch D, Barnes BM, Riess ML) J Comp Physiol B 2017 Jul;187(5-6):715-724 PMID: 28364393 PMCID: PMC6145465 04/02/2017       3 Citations
  • Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pagel PS, Lohr NL, Pritchard KA Jr) J Vis Exp 2017 03 24(121) PMID: 28362381 PMCID: PMC5408651 04/01/2017    
  • An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pillai S, Pagel PS, Lohr NL, Pritchard KA Jr) PLoS One 2016;11(4):e0151999 PMID: 27050551 PMCID: PMC4822818 04/07/2016       4 Citations
  • Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. (Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG, Rajamani A, Schrepfer S, LaDisa JF Jr) Am J Physiol Heart Circ Physiol 2015 Oct;309(7):H1130-40 PMID: 26254329 PMCID: PMC4865061 08/09/2015       2 Citations
  • Isoflurane favorably modulates guanosine triphosphate cyclohydrolase-1 and endothelial nitric oxide synthase during myocardial ischemia and reperfusion injury in rats. (Baotic I, Weihrauch D, Procknow J, Vasquez-Vivar J, Ge ZD, Sudhakaran S, Warltier DC, Kersten JR) Anesthesiology 2015 Sep;123(3):582-9 PMID: 26192027 PMCID: PMC4543441 07/21/2015       4 Citations
  • A novel path of improving heart function after infarction. (Pritchard KA Jr, Weihrauch D) J Mol Cell Cardiol 2015 Jul;84:200-1 PMID: 25944086 PMCID: PMC5665170 05/07/2015    
  • Porous ongrowth surfaces alter osteoblast maturation and mineralization. (Ninomiya JT, Struve JA, Krolikowski J, Hawkins M, Weihrauch D) J Biomed Mater Res A 2015 Jan;103(1):276-81 PMID: 24677492 03/29/2014       7 Citations
  • Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury. (Bangaru ML, Weihrauch D, Tang QB, Zoga V, Hogan Q, Wu HE) Mol Pain 2013 Sep 10;9:47 PMID: 24015960 PMCID: PMC3847629 09/11/2013       28 Citations
  • Inhibition of myeloperoxidase decreases vascular oxidative stress and increases vasodilatation in sickle cell disease mice. (Zhang H, Xu H, Weihrauch D, Jones DW, Jing X, Shi Y, Gourlay D, Oldham KT, Hillery CA, Pritchard KA Jr) J Lipid Res 2013 Nov;54(11):3009-15 PMID: 23956444 PMCID: PMC3793605 08/21/2013       19 Citations
  • N-acetyl lysyltyrosylcysteine amide inhibits myeloperoxidase, a novel tripeptide inhibitor. (Zhang H, Jing X, Shi Y, Xu H, Du J, Guan T, Weihrauch D, Jones DW, Wang W, Gourlay D, Oldham KT, Hillery CA, Pritchard KA Jr) J Lipid Res 2013 Nov;54(11):3016-29 PMID: 23883583 PMCID: PMC3793606 07/26/2013       15 Citations
  • Far red/near infrared light treatment promotes femoral artery collateralization in the ischemic hindlimb. (Lohr NL, Ninomiya JT, Warltier DC, Weihrauch D) J Mol Cell Cardiol 2013 Sep;62:36-42 PMID: 23702287 PMCID: PMC3747970 05/25/2013       8 Citations
  • Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia. (Baotic I, Ge ZD, Sedlic F, Coon A, Weihrauch D, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2013 Jul 15;305(2):H219-27 PMID: 23666677 PMCID: PMC3726953 05/15/2013       15 Citations
  • Metal ions activate vascular endothelial cells and increase lymphocyte chemotaxis and binding. (Ninomiya JT, Kuzma SA, Schnettler TJ, Krolikowski JG, Struve JA, Weihrauch D) J Orthop Res 2013 Sep;31(9):1484-91 PMID: 23629852 PMCID: PMC3957232 05/01/2013       16 Citations
  • Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats. (Yu H, Fischer G, Ferhatovic L, Fan F, Light AR, Weihrauch D, Sapunar D, Nakai H, Park F, Hogan QH) PLoS One 2013;8(4):e61266 PMID: 23613824 PMCID: PMC3628918 04/25/2013       17 Citations
  • 4F decreases IRF5 expression and activation in hearts of tight skin mice. (Xu H, Krolikowski JG, Jones DW, Ge ZD, Pagel PS, Pritchard KA Jr, Weihrauch D) PLoS One 2012;7(12):e52046 PMID: 23251680 PMCID: PMC3522636 12/20/2012       10 Citations
  • Transient repetitive exposure to low level light therapy enhances collateral blood vessel growth in the ischemic hindlimb of the tight skin mouse. (Zaidi M, Krolikowki JG, Jones DW, Pritchard KA Jr, Struve J, Nandedkar SD, Lohr NL, Pagel PS, Weihrauch D) Photochem Photobiol 2013 May-Jun;89(3):709-13 PMID: 23231468 PMCID: PMC3597754 12/13/2012       12 Citations
  • Absence of type VI collagen paradoxically improves cardiac function, structure, and remodeling after myocardial infarction. (Luther DJ, Thodeti CK, Shamhart PE, Adapala RK, Hodnichak C, Weihrauch D, Bonaldo P, Chilian WM, Meszaros JG) Circ Res 2012 Mar 16;110(6):851-6 PMID: 22343710 PMCID: PMC3954719 02/22/2012       37 Citations
  • Hexosamine pathway activation and O-linked-N-acetylglucosamine: novel mediators of endothelial dysfunction in hyperglycemia and diabetes. (Beyer AM, Weihrauch D) Vascul Pharmacol 2012 Mar-Apr;56(3-4):113-4 PMID: 22289438 02/01/2012       3 Citations
  • Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning. (Hirata N, Shim YH, Pravdic D, Lohr NL, Pratt PF Jr, Weihrauch D, Kersten JR, Warltier DC, Bosnjak ZJ, Bienengraeber M) Anesthesiology 2011 Sep;115(3):531-40 PMID: 21862887 PMCID: PMC3337729 08/25/2011       49 Citations
  • Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection. (Leucker TM, Bienengraeber M, Muravyeva M, Baotic I, Weihrauch D, Brzezinska AK, Warltier DC, Kersten JR, Pratt PF Jr) J Mol Cell Cardiol 2011 Nov;51(5):803-11 PMID: 21791217 PMCID: PMC3342532 07/28/2011       30 Citations
  • Store-operated Ca2+ entry in sensory neurons: functional role and the effect of painful nerve injury. (Gemes G, Bangaru ML, Wu HE, Tang Q, Weihrauch D, Koopmeiners AS, Cruikshank JM, Kwok WM, Hogan QH) J Neurosci 2011 Mar 09;31(10):3536-49 PMID: 21389210 PMCID: PMC3565463 03/11/2011       59 Citations
  • Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis. (Xu H, Zaidi M, Struve J, Jones DW, Krolikowski JG, Nandedkar S, Lohr NL, Gadicherla A, Pagel PS, Csuka ME, Pritchard KA, Weihrauch D) Am J Physiol Cell Physiol 2011 Mar;300(3):C550-6 PMID: 21160034 PMCID: PMC3063974 12/17/2010       25 Citations
  • D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma. (Nandedkar SD, Weihrauch D, Xu H, Shi Y, Feroah T, Hutchins W, Rickaby DA, Duzgunes N, Hillery CA, Konduri KS, Pritchard KA Jr) J Lipid Res 2011 Mar;52(3):499-508 PMID: 21131532 PMCID: PMC3035686 12/07/2010       39 Citations
  • Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes. (Widlansky ME, Wang J, Shenouda SM, Hagen TM, Smith AR, Kizhakekuttu TJ, Kluge MA, Weihrauch D, Gutterman DD, Vita JA) Transl Res 2010 Jul;156(1):15-25 PMID: 20621033 PMCID: PMC2904361 07/14/2010       68 Citations
  • Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70 PMID: 20498409 PMCID: PMC2918439 05/26/2010       49 Citations
  • Hyperglycemia adversely modulates endothelial nitric oxide synthase during anesthetic preconditioning through tetrahydrobiopterin- and heat shock protein 90-mediated mechanisms. (Amour J, Brzezinska AK, Jager Z, Sullivan C, Weihrauch D, Du J, Vladic N, Shi Y, Warltier DC, Pratt PF Jr, Kersten JR) Anesthesiology 2010 Mar;112(3):576-85 PMID: 20124983 PMCID: PMC2888104 02/04/2010    
  • KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy. (Zoga V, Kawano T, Liang MY, Bienengraeber M, Weihrauch D, McCallum B, Gemes G, Hogan Q, Sarantopoulos C) Mol Pain 2010 Jan 26;6:6 PMID: 20102598 PMCID: PMC2825500 01/28/2010       36 Citations
  • Myocardial interstitial fluid inhibits proliferation and cardiomyocyte differentiation in pluripotent embryonic stem cells. (Van Orman JR, Weihrauch D, Warltier DC, Lough J) Am J Physiol Heart Circ Physiol 2009 Oct;297(4):H1369-76 PMID: 19633209 PMCID: PMC2770771 07/28/2009       1 Citations
  • Depletion of calcium stores in injured sensory neurons: anatomic and functional correlates. (Gemes G, Rigaud M, Weyker PD, Abram SE, Weihrauch D, Poroli M, Zoga V, Hogan QH) Anesthesiology 2009 Aug;111(2):393-405 PMID: 19602957 PMCID: PMC2885290 07/16/2009       15 Citations
  • Mechanism of differential cardiovascular response to propofol in Dahl salt-sensitive, Brown Norway, and chromosome 13-substituted consomic rat strains: role of large conductance Ca2+ and voltage-activated potassium channels. (Stadnicka A, Contney SJ, Moreno C, Weihrauch D, Bosnjak ZJ, Roman RJ, Stekiel TA) J Pharmacol Exp Ther 2009 Sep;330(3):727-35 PMID: 19541907 PMCID: PMC2729794 06/23/2009       7 Citations
  • Morphine reduces the threshold of helium preconditioning against myocardial infarction: the role of opioid receptors in rabbits. (Pagel PS, Krolikowski JG, Amour J, Warltier DC, Weihrauch D) J Cardiothorac Vasc Anesth 2009 Oct;23(5):619-24 PMID: 19231239 PMCID: PMC4401574 02/24/2009       26 Citations
  • Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning. (Amour J, Brzezinska AK, Weihrauch D, Billstrom AR, Zielonka J, Krolikowski JG, Bienengraeber MW, Warltier DC, Pratt PF Jr, Kersten JR) Anesthesiology 2009 Feb;110(2):317-25 PMID: 19194158 PMCID: PMC2730207 02/06/2009       45 Citations
  • Inhibition of glycogen synthase kinase or the apoptotic protein p53 lowers the threshold of helium cardioprotection in vivo: the role of mitochondrial permeability transition. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) Anesth Analg 2008 Sep;107(3):769-75 PMID: 18713881 PMCID: PMC2569871 08/21/2008       24 Citations
  • The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) Anesth Analg 2008 Sep;107(3):762-8 PMID: 18713880 PMCID: PMC2569865 08/21/2008       26 Citations
  • Reactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo. (Pagel PS, Krolikowski JG, Pratt PF Jr, Shim YH, Amour J, Warltier DC, Weihrauch D) J Cardiothorac Vasc Anesth 2008 Aug;22(4):554-9 PMID: 18662630 PMCID: PMC2568984 07/30/2008       26 Citations
  • Histopathology of experimentally induced asthma in a murine model of sickle cell disease. (Nandedkar SD, Feroah TR, Hutchins W, Weihrauch D, Konduri KS, Wang J, Strunk RC, DeBaun MR, Hillery CA, Pritchard KA) Blood 2008 Sep 15;112(6):2529-38 PMID: 18579795 PMCID: PMC2532817 06/27/2008       33 Citations
  • Telokin expression and the effect of hypoxia on its phosphorylation status in smooth muscle cells from small and large pulmonary arteries. (Madden JA, Dantuma MW, Sorokina EA, Weihrauch D, Kleinman JG) Am J Physiol Lung Cell Mol Physiol 2008 Jun;294(6):L1166-73 PMID: 18375742 04/01/2008       9 Citations
  • Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection. (Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) J Cardiovasc Pharmacol 2007 Dec;50(6):670-6 PMID: 18091584 12/20/2007       14 Citations
  • Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. (Pagel PS, Krolikowski JG, Shim YH, Venkatapuram S, Kersten JR, Weihrauch D, Warltier DC, Pratt PF Jr) Anesth Analg 2007 Sep;105(3):562-9 PMID: 17717207 08/25/2007       87 Citations
  • Effects of D-4F on vasodilation, oxidative stress, angiostatin, myocardial inflammation, and angiogenic potential in tight-skin mice. (Weihrauch D, Xu H, Shi Y, Wang J, Brien J, Jones DW, Kaul S, Komorowski RA, Csuka ME, Oldham KT, Pritchard KA) Am J Physiol Heart Circ Physiol 2007 Sep;293(3):H1432-41 PMID: 17496220 05/15/2007       59 Citations
  • Efficient transgenic rat production by a lentiviral vector. (Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW Jr) Am J Physiol Heart Circ Physiol 2007 Jul;293(1):H881-94 PMID: 17322424 02/27/2007       35 Citations
  • Inhibition of apoptotic protein p53 lowers the threshold of isoflurane-induced cardioprotection during early reperfusion in rabbits. (Venkatapuram S, Wang C, Krolikowski JG, Weihrauch D, Kersten JR, Warltier DC, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Dec;103(6):1400-5 PMID: 17122210 11/24/2006       33 Citations
  • Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats. (Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):281-8, table of contents PMID: 16861403 07/25/2006       63 Citations
  • Gender-specificity of delayed preconditioning by isoflurane in rabbits: potential role of endothelial nitric oxide synthase. (Wang C, Chiari PC, Weihrauch D, Krolikowski JG, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):274-80, table of contents PMID: 16861402 07/25/2006       33 Citations
  • Rosiglitazone antagonizes vascular endothelial growth factor signaling and nuclear factor of activated T cells activation in cardiac valve endothelium. (Sander TL, Noll L, Klinkner DB, Weihrauch D, He BJ, Kaul S, Zangwill SD, Tweddell JS, Pritchard KA Jr, Oldham KT) Endothelium 2006 May-Jun;13(3):181-90 PMID: 16840174 07/15/2006       6 Citations
  • Cardioprotection by volatile anesthetics: new applications for old drugs? (Pratt PF Jr, Wang C, Weihrauch D, Bienengraeber MW, Kersten JR, Pagel PS, Warltier DC) Curr Opin Anaesthesiol 2006 Aug;19(4):397-403 PMID: 16829721 07/11/2006       28 Citations
  • Endothelium-derived microparticles inhibit human cardiac valve endothelial cell function. (Klinkner DB, Densmore JC, Kaul S, Noll L, Lim HJ, Weihrauch D, Pritchard KA Jr, Oldham KT, Sander TL) Shock 2006 Jun;25(6):575-80 PMID: 16721264 05/25/2006       41 Citations
  • The influence of B-cell lymphoma 2 protein, an antiapoptotic regulator of mitochondrial permeability transition, on isoflurane-induced and ischemic postconditioning in rabbits. (Wang C, Neff DA, Krolikowski JG, Weihrauch D, Bienengraeber M, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2006 May;102(5):1355-60 PMID: 16632808 04/25/2006       46 Citations
  • Inhibition of glycogen synthase kinase enhances isoflurane-induced protection against myocardial infarction during early reperfusion in vivo. (Pagel PS, Krolikowski JG, Neff DA, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC) Anesth Analg 2006 May;102(5):1348-54 PMID: 16632807 04/25/2006       54 Citations
  • Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo. (Krolikowski JG, Weihrauch D, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Can J Anaesth 2006 Feb;53(2):174-82 PMID: 16434759 01/26/2006       75 Citations
  • Inhibition of mitochondrial permeability transition enhances isoflurane-induced cardioprotection during early reperfusion: the role of mitochondrial KATP channels. (Krolikowski JG, Bienengraeber M, Weihrauch D, Warltier DC, Kersten JR, Pagel PS) Anesth Analg 2005 Dec;101(6):1590-6 PMID: 16301224 11/23/2005       102 Citations
  • Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression. (Jamnicki-Abegg M, Weihrauch D, Pagel PS, Kersten JR, Bosnjak ZJ, Warltier DC, Bienengraeber MW) Anesthesiology 2005 Nov;103(5):1006-14 PMID: 16249675 10/27/2005    
  • Morphine enhances isoflurane-induced postconditioning against myocardial infarction: the role of phosphatidylinositol-3-kinase and opioid receptors in rabbits. (Weihrauch D, Krolikowski JG, Bienengraeber M, Kersten JR, Warltier DC, Pagel PS) Anesth Analg 2005 Oct;101(4):942-9, table of contents PMID: 16192500 09/30/2005       87 Citations
  • Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium. (Chiari PC, Bienengraeber MW, Weihrauch D, Krolikowski JG, Kersten JR, Warltier DC, Pagel PS) Anesthesiology 2005 Jul;103(1):74-83 PMID: 15983459 06/29/2005    
  • Cardioprotection by volatile anesthetics. (Bienengraeber MW, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Vascul Pharmacol 2005 Apr-May;42(5-6):243-52 PMID: 15922257 06/01/2005       52 Citations
  • Haptoglobin expression and activity during coronary collateralization. (Lohr NL, Warltier DC, Chilian WM, Weihrauch D) Am J Physiol Heart Circ Physiol 2005 Mar;288(3):H1389-95 PMID: 15550518 11/20/2004       21 Citations
  • Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. (Ludwig LM, Tanaka K, Eells JT, Weihrauch D, Pagel PS, Kersten JR, Warltier DC) Anesth Analg 2004 Nov;99(5):1308-15; table of contents PMID: 15502022 10/27/2004       53 Citations
  • Protein kinase C-epsilon primes the cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel to modulation by isoflurane. (Aizawa K, Turner LA, Weihrauch D, Bosnjak ZJ, Kwok WM) Anesthesiology 2004 Aug;101(2):381-9 PMID: 15277921 07/28/2004       35 Citations
  • Autologous vascular smooth muscle cell-based myocardial gene therapy to induce coronary collateral growth. (Hattan N, Warltier D, Gu W, Kolz C, Chilian WM, Weihrauch D) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H488-93 PMID: 15277192 07/28/2004       23 Citations
  • Chronic hyperglycemia attenuates coronary collateral development and impairs proliferative properties of myocardial interstitial fluid by production of angiostatin. (Weihrauch D, Lohr NL, Mraovic B, Ludwig LM, Chilian WM, Pagel PS, Warltier DC, Kersten JR) Circulation 2004 May 18;109(19):2343-8 PMID: 15136506 05/12/2004       67 Citations
  • Protein kinase C translocation and Src protein tyrosine kinase activation mediate isoflurane-induced preconditioning in vivo: potential downstream targets of mitochondrial adenosine triphosphate-sensitive potassium channels and reactive oxygen species. (Ludwig LM, Weihrauch D, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2004 Mar;100(3):532-9 PMID: 15108965 04/28/2004       84 Citations
  • Angiostatin and matrix metalloprotease expression following ischemic acute renal failure. (Basile DP, Fredrich K, Weihrauch D, Hattan N, Chilian WM) Am J Physiol Renal Physiol 2004 May;286(5):F893-902 PMID: 15075185 04/13/2004       98 Citations
  • Reactive oxygen species are critical mediators of coronary collateral development in a canine model. (Gu W, Weihrauch D, Tanaka K, Tessmer JP, Pagel PS, Kersten JR, Chilian WM, Warltier DC) Am J Physiol Heart Circ Physiol 2003 Oct;285(4):H1582-9 PMID: 12816750 06/21/2003       43 Citations
  • N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia. (Kehl F, Krolikowski JG, Weihrauch D, Pagel PS, Warltier DC, Kersten JR) Anesthesiology 2003 Jun;98(6):1384-90 PMID: 12766647 05/27/2003       25 Citations
  • L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. (Ou J, Ou Z, Jones DW, Holzhauer S, Hatoum OA, Ackerman AW, Weihrauch DW, Gutterman DD, Guice K, Oldham KT, Hillery CA, Pritchard KA Jr) Circulation 2003 May 13;107(18):2337-41 PMID: 12732610 05/07/2003       116 Citations
  • Mitochondrial adenosine triphosphate-regulated potassium channel opening acts as a trigger for isoflurane-induced preconditioning by generating reactive oxygen species. (Tanaka K, Weihrauch D, Ludwig LM, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2003 Apr;98(4):935-43 PMID: 12657856 03/27/2003       109 Citations
  • Expression of VEGF and angiopoietins-1 and -2 during ischemia-induced coronary angiogenesis. (Matsunaga T, Warltier DC, Tessmer J, Weihrauch D, Simons M, Chilian WM) Am J Physiol Heart Circ Physiol 2003 Jul;285(1):H352-8 PMID: 12649074 03/22/2003       83 Citations
  • Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. (Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1552-9 PMID: 12543642 01/25/2003       53 Citations
  • Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. (Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2002 Dec;97(6):1485-90 PMID: 12459675 12/03/2002       142 Citations
  • An intramyocardial catheter for repeated in vivo sampling of interstitial fluid. (Tessmer JP, Pagel PS, Weihrauch D, Ludwig LM, Chilian WM, Kersten JR, Warltier DC) J Pharmacol Toxicol Methods 2002 Mar-Apr;47(2):73-8 PMID: 12459145 12/03/2002       4 Citations
  • Angiostatin inhibits coronary angiogenesis during impaired production of nitric oxide. (Matsunaga T, Weihrauch DW, Moniz MC, Tessmer J, Warltier DC, Chilian WM) Circulation 2002 May 07;105(18):2185-91 PMID: 11994253 05/08/2002       114 Citations
  • Ischemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide. (Matsunaga T, Warltier DC, Weihrauch DW, Moniz M, Tessmer J, Chilian WM) Circulation 2000 Dec 19;102(25):3098-103 PMID: 11120701 01/11/2000       185 Citations
  • Effects of transforming growth factor-beta and mechanical strain on osteoblast cell counts: an in vitro model for distraction osteogenesis. (Gosain AK, Song LS, Santoro T, Weihrauch D, Bosi BO, Corrao MA, Chilian WM) Plast Reconstr Surg 2000 Jan;105(1):130-6; discussion 137-9 PMID: 10626981 01/08/2000       22 Citations
  • Ischemia-induced coronary collateral angiogenesis. (Weihrauch D, Tessmer JP, Kersten JR, Pagel PS, Hettrick DA, Chilian WM, Warltier DC) Adv Exp Med Biol 1998;454:281-6 PMID: 9889902 01/16/1999       2 Citations
  • Repetitive coronary artery occlusions induce release of growth factors into the myocardial interstitium. (Weihrauch D, Tessmer J, Warltier DC, Chilian WM) Am J Physiol 1998 Sep;275(3 Pt 2):H969-76 PMID: 9724302 09/02/1998       34 Citations
  • Nitric oxide (NO) and oxygen radicals, but not prostaglandins, modulate fever. (Weihrauch D, Riedel W) Ann N Y Acad Sci 1997 Mar 15;813:373-82 PMID: 9100909 03/15/1997       24 Citations
  • Coordinate expression of the insulin-like growth factor system after microembolisation in porcine heart. (Kluge A, Zimmermann R, Weihrauch D, Mohri M, Sack S, Schaper J, Schaper W) Cardiovasc Res 1997 Feb;33(2):324-31 PMID: 9074696 02/01/1997       35 Citations
  • Importance of monocytes/macrophages and fibroblasts for healing of micronecroses in porcine myocardium. (Weihrauch D, Arras M, Zimmermann R, Schaper J) Mol Cell Biochem 1995 Jun 7-21;147(1-2):13-9 PMID: 7494542 06/07/1995       38 Citations
  • Expression of extracellular matrix proteins and the role of fibroblasts and macrophages in repair processes in ischemic porcine myocardium. (Weihrauch D, Zimmermann R, Arras M, Schaper J) Cell Mol Biol Res 1994;40(2):105-16 PMID: 7849762 01/01/1994       19 Citations
  • The extracellular matrix in human cardiac tissue. Part II: Vimentin, laminin, and fibronectin. (Speiser B, Weihrauch D, Riess CF, Schaper J) Cardioscience 1992 Mar;3(1):41-9 PMID: 1554870 03/01/1992       33 Citations
  • Last update: 12/26/2018
    jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad