Medical College of Wisconsin
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Jason A. Jarzembowski MD, PhD

Jason A. Jarzembowski MD, PhD

Vice Chair, Chief, Professor

Institution: Medical College of Wisconsin
Department: Pathology
Division: Administration
Program: Pediatrics

Member of the Cancer Center
Member of the Cardiovascular Center
Member of the Genomic Sciences and Precision Medicine Center (GSPMC)


I am willing to mentor a junior faculty member.


Clinical Expertise

  • Autopsy
  • Neuroblastoma
  • Pathology, Surgical
  • Placenta
  • Fetal & Perinatal Pathology
  • Leadership Positions

  • Director. CRI Research Core Laboratories
  • Program Director, Perinatal Pathology
  • Medical Advisor, Infant Death Center of Wisconsin
  • Division Director, Pediatric Pathology, MCW Department of Pathology
  • Chair, Pathology Discipline Committee, Children's Oncology Group
  • Medical Director, Pathology and Laboratory Medicine, Children's Hospital of Wisconsin
  • Publications (66)

  • Decreased OLA1 (Obg-Like ATPase-1) Expression Drives Ubiquitin-Proteasome Pathways to Downregulate Mitochondrial SOD2 (Superoxide Dismutase) in Persistent Pulmonary Hypertension of the Newborn. (Schultz A, Olorundami OA, Teng RJ, Jarzembowski J, Shi ZZ, Kumar SN, Pritchard K Jr, Konduri GG, Afolayan AJ) Hypertension 2019 Oct;74(4):957-966 PMID: 31476900 PMCID: PMC6739165 SCOPUS ID: 2-s2.0-85072134040 09/04/2019    
  • TH cells' capacity for TH1 and TH17 differentiation is attenuated in children with nontuberculous mycobacteria infection. (Claeys TA, Rosas Mejia O, Marshall S, Jarzembowski JA, Hayes D Jr, Hull NM, Liyanage NPM, Chun RH, Sulman CG, Huppler AR, Robinson RT) J Infect Dis 2019 07 23 PMID: 31332447 07/25/2019    
  • Adequacy and Accuracy of Core Biopsy in Children: A Radiologic/Pathologic Correlation Study. (Parsons LN, Vo N, Moe DC, Jarzembowski JA) Pediatr Dev Pathol 2019 Mar-Apr;22(2):137-141 PMID: 30428273 SCOPUS ID: 2-s2.0-85059101319 11/15/2018    
  • Skip Segment Hirschsprung Disease and Waardenburg Syndrome. (Gross ER, Geddes GC, McCarrier JA, Jarzembowski JA, Arca MJ) J Pediatr Surg Case Reports, 2015; 3:143-145 03/27/2018    
  • Extraspinal sacrococcygeal ependymoma masquerading as sacrococcygeal teratoma in the pediatric patient. (Amin R, Berdan E, Knipstein J, Jarzembowski J, Siddiqui S) Pediatr Surg Int 2018 01;34(1):109-112 PMID: 29138922 SCOPUS ID: 2-s2.0-85033713826 11/16/2017    
  • CD30 Expression in Monomorphic Posttransplant Lymphoproliferative Disorder, Diffuse Large B-Cell Lymphoma Correlates With Greater Regulatory T-Cell Infiltration. (Hartley C, Vaughan JW, Jarzembowski J, Kroft SH, Hosking P, Harrington AM, Olteanu H) Am J Clin Pathol 2017 Nov 20;148(6):485-493 PMID: 29126177 SCOPUS ID: 2-s2.0-85038129680 11/11/2017       3 Citations
  • Paired Expression Analysis of Tumor Cell Surface Antigens. (Orentas RJ, Sindiri S, Duris C, Wen X, He J, Wei JS, Jarzembowski J, Khan J) Front Oncol 2017;7:173 PMID: 28871274 PMCID: PMC5566986 09/06/2017    
  • Caffeine ameliorates hyperoxia-induced lung injury by protecting GCH1 function in neonatal rat pups. (Jing X, Huang YW, Jarzembowski J, Shi Y, Konduri GG, Teng RJ) Pediatr Res 2017 Sep;82(3):483-489 PMID: 28399119 PMCID: PMC5570644 SCOPUS ID: 2-s2.0-85028332881 04/12/2017       10 Citations
  • An Evidence-based Recommendation for a Standardized Approach to Detecting Metastatic Neuroblastoma in Staging Bone Marrow Biopsies. (Parsons LN, Gheorghe G, Yan K, Simpson P, Jarzembowski JA) Pediatr Dev Pathol 2017 Jan-Feb;20(1):38-43 PMID: 28276294 SCOPUS ID: 2-s2.0-85027123831 03/10/2017    
  • Clinicopathologic analysis of malignant effusions in pediatric patients. (Parsons LN, Jarzembowski JA) J Am Soc Cytopathol 2017 Mar - Apr;6(2):41-47 PMID: 31042633 SCOPUS ID: 2-s2.0-85007564103 01/01/2017    
  • Erratum to "Infant with nasolacrimal sinonasal myxoma: Diffusion MRI features" [Radiology Case Reports 2015;10: article 1104]. (Kelly TG, Hong S, Jarzembowski J, Beste D) Radiol Case Rep 2017 Mar;12(1):210 PMID: 29379581 PMCID: PMC5767574 11/18/2016    
  • Pediatric renal and genitourinary tract tumors and the contributions of Dr. Louis "Pepper" Dehner therewith. (Jarzembowski JA) Semin Diagn Pathol 2016 Nov;33(6):419-426 PMID: 27720562 SCOPUS ID: 2-s2.0-84992021947 10/11/2016       1 Citation
  • Placental TLR/NLR expression signatures are altered with gestational age and inflammation. (Kumar N, Nandula P, Menden H, Jarzembowski J, Sampath V) J Matern Fetal Neonatal Med 2017 Jul;30(13):1588-1595 PMID: 27440318 SCOPUS ID: 2-s2.0-85016126125 07/22/2016       4 Citations
  • Pediatric pedunculated perianal problems (Massoumi RL, Parsons LN, Jarzembowski JA, Wagner AJ) Journal of Pediatric Surgery Case Reports 1 June 2016;9:45-48 SCOPUS ID: 2-s2.0-84969245598 06/01/2016    
  • An evidence-based recommendation for a standardized approach to detecting metastatic neuroblastoma in staging bone marrow biopsies. (Parsons LN, Gheorghe G, Yan K, Simpson P, Jarzembowski JA) Pediatr Dev Pathol 2016 Mar 28: PMID: 27018850 03/29/2016    
  • Potentially diagnostic electron paramagnetic resonance spectra elucidate the underlying mechanism of mitochondrial dysfunction in the deoxyguanosine kinase deficient rat model of a genetic mitochondrial DNA depletion syndrome. (Bennett B, Helbling D, Meng H, Jarzembowski J, Geurts AM, Friederich MW, Van Hove JLK, Lawlor MW, Dimmock DP) Free Radic Biol Med 2016 Mar;92:141-151 PMID: 26773591 PMCID: PMC5047058 SCOPUS ID: 2-s2.0-84957568061 01/17/2016       7 Citations
  • Author's Reply. (Parsons L, Jarzembowski J) Pediatr Dev Pathol 2016 May-Jun;19(3):256-7 PMID: 26600427 11/26/2015    
  • Improving Detection of Metastatic Neuroblastoma in Bone Marrow Core Biopsies: A Proposed Immunohistochemical Approach. (Parsons LN, Gheorghe G, Yan K, Simpson P, Jarzembowski JA) Pediatr Dev Pathol 2016 May-Jun;19(3):230-6 PMID: 26491958 SCOPUS ID: 2-s2.0-84977628154 10/23/2015       5 Citations
  • A toll-like receptor 9 (rs352140) variant is associated with placental inflammation in newborn infants. (Karody V, Reese S, Kumar N, Liedel J, Jarzembowski J, Sampath V) J Matern Fetal Neonatal Med 2016;29(13):2210-6 PMID: 26371589 PMCID: PMC5238957 SCOPUS ID: 2-s2.0-84941662570 09/16/2015       6 Citations
  • Pediatric Malignancies: Pathology and Imaging Pediatric Malignancies: Pathology and Imaging . D.M . Parham , J.D . Khoury , and M.B . McCarville , editors . Springer , New York, NY , 2015 , ISBN 978-1-4939-1728-0 , $179.00 , 429 pp., hardcover; ISBN 978-1-4939-1729-7 , $139 , e-book. (Jarzembowski J) Pediatr Dev Pathol 2015 Sep-Oct;18(5):427-8 PMID: 26230738 08/01/2015    
  • Skip segment Hirschsprung disease and Waardenburg syndrome (Gross ER, Geddes GC, McCarrier JA, Jarzembowski JA, Arca MJ) Journal of Pediatric Surgery Case Reports 1 April 2015;3(4):143-145 SCOPUS ID: 2-s2.0-84928657376 04/01/2015    
  • Infant with nasolacrimal sinonasal myxoma: Diffusion MRI features. (Kelly TG, Hong S, Jarzembowski J, Beste D) Radiol Case Rep 2015;10(2):1104 PMID: 27398121 PMCID: PMC4921178 01/01/2015    
  • The role of neutrophil myeloperoxidase in models of lung tumor development. (Rymaszewski AL, Tate E, Yimbesalu JP, Gelman AE, Jarzembowski JA, Zhang H, Pritchard KA Jr, Vikis HG) Cancers (Basel) 2014 May 09;6(2):1111-27 PMID: 24821130 PMCID: PMC4074819 SCOPUS ID: 2-s2.0-84901207748 05/14/2014    
  • Imprinting Disorders (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:187-187 SCOPUS ID: 2-s2.0-85043298935 01/01/2014    
  • Chromosome 22q AbnormaLities (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:184-184 SCOPUS ID: 2-s2.0-85043293619 01/01/2014    
  • Channelopathies (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:194-194 SCOPUS ID: 2-s2.0-85043292469 01/01/2014    
  • Trisomies (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:183-183 SCOPUS ID: 2-s2.0-85043288160 01/01/2014    
  • Sudden Infant Death Syndrome (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:212-212 SCOPUS ID: 2-s2.0-85043287085 01/01/2014    
  • Sex Chromosome AbnormaLities (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:185-185 SCOPUS ID: 2-s2.0-85043284722 01/01/2014    
  • Neuroblastic Tumors (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:213-213 SCOPUS ID: 2-s2.0-85043266449 01/01/2014    
  • Normal Structure and Function of the Placenta (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:2308-2321 SCOPUS ID: 2-s2.0-85043255070 01/01/2014    
  • LateraLity Disorders (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:181-182 SCOPUS ID: 2-s2.0-85043231037 01/01/2014    
  • Triplet Repeat Disorders (Jarzembowski JA) Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms 1 January 2014:186-186 SCOPUS ID: 2-s2.0-85043247759 01/01/2014    
  • Re: Needle core vs open biopsy for diagnosis of intermediate- and high-risk neuroblastoma in children. (Jarzembowski JA, Lal DR, Shimada H) J Pediatr Surg 2012 Nov;47(11):2162-3; author reply 2163-5 PMID: 23164019 SCOPUS ID: 2-s2.0-84877111300 11/21/2012       1 Citation
  • Pediatric autopsy consent: helping families create hope out of despair. (Jarzembowski JA, Hicks MJ) Pediatr Blood Cancer 2013 Feb;60(2):173-4 PMID: 23109284 SCOPUS ID: 2-s2.0-84871110045 10/31/2012       1 Citation
  • Peripheral neuroblastic tumors with genotype-phenotype discordance: a report from the Children's Oncology Group and the International Neuroblastoma Pathology Committee. (Suganuma R, Wang LL, Sano H, Naranjo A, London WB, Seeger RC, Hogarty MD, Gastier-Foster JM, Look AT, Park JR, Maris JM, Cohn SL, Amann G, Beiske K, Cullinane CJ, d'Amore ES, Gambini C, Jarzembowski JA, Joshi VV, Navarro S, Peuchmaur M, Shimada H) Pediatr Blood Cancer 2013 Mar;60(3):363-70 PMID: 22744966 PMCID: PMC3397468 SCOPUS ID: 2-s2.0-84872472525 06/30/2012       13 Citations
  • Molecular techniques in pediatric pathology (Jarzembowski JA, Hill DA) Stocker and Dehner's Pediatric Pathology: Third Edition 28 March 2012 SCOPUS ID: 2-s2.0-84973527722 03/28/2012    
  • DICER1 mutations in embryonal rhabdomyosarcomas from children with and without familial PPB-tumor predisposition syndrome. (Doros L, Yang J, Dehner L, Rossi CT, Skiver K, Jarzembowski JA, Messinger Y, Schultz KA, Williams G, AndrĂ© N, Hill DA) Pediatr Blood Cancer 2012 Sep;59(3):558-60 PMID: 22180160 PMCID: PMC3708486 SCOPUS ID: 2-s2.0-84863863372 12/20/2011       78 Citations
  • Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations. (Dehner LP, Jarzembowski JA, Hill DA) Mod Pathol 2012 Apr;25(4):602-14 PMID: 22157934 PMCID: PMC5031244 SCOPUS ID: 2-s2.0-84859424582 12/14/2011       59 Citations
  • HDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in neuroblastoma. (Subramanian C, Jarzembowski JA, Opipari AW Jr, Castle VP, Kwok RP) Neoplasia 2011 Aug;13(8):726-34 PMID: 21847364 PMCID: PMC3156663 08/19/2011    
  • In response (Dehner LP, Dishop MK, Jarzembowski J, Hill DA) American Journal of Surgical Pathology July 2011;35(7):1086-1087 SCOPUS ID: 2-s2.0-79959650769 07/01/2011    
  • Next-generation sequencing facilitates the diagnosis in a child with twinkle mutations causing cholestatic liver failure. (Goh V, Helbling D, Biank V, Jarzembowski J, Dimmock D) J Pediatr Gastroenterol Nutr 2012 Feb;54(2):291-4 PMID: 21681116 SCOPUS ID: 2-s2.0-84856257607 06/18/2011       30 Citations
  • Fetal lung interstitial tumor (FLIT): A proposed newly recognized lung tumor of infancy to be differentiated from cystic pleuropulmonary blastoma and other developmental pulmonary lesions. (Dishop MK, McKay EM, Kreiger PA, Priest JR, Williams GM, Langston C, Jarzembowski J, Suchi M, Dehner LP, Hill DA) Am J Surg Pathol 2010 Dec;34(12):1762-72 PMID: 21107081 SCOPUS ID: 2-s2.0-78650396655 11/26/2010       27 Citations
  • CLU blocks HDACI-mediated killing of neuroblastoma. (Subramanian C, Jarzembowski JA, Halsey SM, Kuick R, Opipari AW Jr, Castle VP, Kwok RP) Tumour Biol 2011 Apr;32(2):285-94 PMID: 21042904 PMCID: PMC3041908 SCOPUS ID: 2-s2.0-79953772135 11/03/2010       1 Citation
  • Endothelial microparticles induce inflammation in acute lung injury. (Buesing KL, Densmore JC, Kaul S, Pritchard KA Jr, Jarzembowski JA, Gourlay DM, Oldham KT) J Surg Res 2011 Mar;166(1):32-9 PMID: 20828748 PMCID: PMC4731030 SCOPUS ID: 2-s2.0-79951678163 09/11/2010       38 Citations
  • Genetic Disorders and the Fetus: Diagnosis, Prevention, and Treatment Genetic Disorders and the Fetus: Diagnosis, Prevention, and Treatment . A. Milunsky , J. M. Milunsky . Wiley-Blackwell . Hoboken, NJ . 2010 . 1171 pp., hardcover, including images, tables, and color plates . (Jarzembowski J) Pediatr Dev Pathol 2011 Jan-Feb;14(1):84 PMID: 20524808 06/08/2010    
  • Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70 PMID: 20498409 PMCID: PMC2918439 SCOPUS ID: 2-s2.0-77956861083 05/26/2010       50 Citations
  • Bcl6 is expressed in neuroblastoma: tumor cell type-specific expression predicts outcome. (Chamdin A, Jarzembowski JA, Subramanian C, Kuick R, Lee JS, Kwok RP, Castle VP, Opipari AW) Transl Oncol 2009 Aug 18;2(3):128-37 PMID: 19701497 PMCID: PMC2730138 08/25/2009    
  • DICER1 mutations in familial pleuropulmonary blastoma. (Hill DA, Ivanovich J, Priest JR, Gurnett CA, Dehner LP, Desruisseau D, Jarzembowski JA, Wikenheiser-Brokamp KA, Suarez BK, Whelan AJ, Williams G, Bracamontes D, Messinger Y, Goodfellow PJ) Science 2009 Aug 21;325(5943):965 PMID: 19556464 PMCID: PMC3098036 SCOPUS ID: 2-s2.0-67749129007 06/27/2009       347 Citations
  • Comprehensive profiling of the cell surface proteome of Sy5Y neuroblastoma cells yields a subset of proteins associated with tumor differentiation. (Garcia J, Faca V, Jarzembowski J, Zhang Q, Park J, Hanash S) J Proteome Res 2009 Aug;8(8):3791-6 PMID: 19505085 SCOPUS ID: 2-s2.0-68549122966 06/10/2009       13 Citations
  • Nontuberculous mycobacterial infections. (Jarzembowski JA, Young MB) Arch Pathol Lab Med 2008 Aug;132(8):1333-41 PMID: 18684037 SCOPUS ID: 2-s2.0-49449094006 08/08/2008       103 Citations
  • Wagner-Meissner neurilemmoma of the right cheek. (Wu AJ, Jarzembowski J, Morag Y, Lucas DR) Ann Diagn Pathol 2008 Jun;12(3):204-7 PMID: 18486897 SCOPUS ID: 2-s2.0-43449083754 05/20/2008       3 Citations
  • Type I pleuropulmonary blastoma: pathology and biology study of 51 cases from the international pleuropulmonary blastoma registry. (Hill DA, Jarzembowski JA, Priest JR, Williams G, Schoettler P, Dehner LP) Am J Surg Pathol 2008 Feb;32(2):282-95 PMID: 18223332 SCOPUS ID: 2-s2.0-38649108175 01/29/2008       128 Citations
  • CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A. (Subramanian C, Jarzembowski JA, Opipari AW Jr, Castle VP, Kwok RP) Neoplasia 2007 Jun;9(6):495-503 PMID: 17603632 PMCID: PMC1899529 SCOPUS ID: 2-s2.0-34250822248 07/03/2007       21 Citations
  • Type IV collagen immunostaining is a simple, reliable diagnostic tool for distinguishing between adenomatous and normal pituitary glands. (Jarzembowski J, Lloyd R, McKeever P) Arch Pathol Lab Med 2007 Jun;131(6):931-5 PMID: 17550321 SCOPUS ID: 2-s2.0-34250208465 06/07/2007       6 Citations
  • Anaplastic large cell lymphoma: looks can be deceiving. (Jarzembowski JA) Pediatr Dev Pathol 2007 May-Jun;10(3):169-71 PMID: 17535094 SCOPUS ID: 2-s2.0-34447646733 05/31/2007    
  • Tubedown expression correlates with the differentiation status and aggressiveness of neuroblastic tumors. (Martin DT, Gendron RL, Jarzembowski JA, Perry A, Collins MH, Pushpanathan C, Miskiewicz E, Castle VP, Paradis H) Clin Cancer Res 2007 Mar 01;13(5):1480-7 PMID: 17332292 SCOPUS ID: 2-s2.0-33947424032 03/03/2007       12 Citations
  • Examining the relationship between positive mid-gestational fetal fibronectin assays and histological evidence of acute placental inflammation. (Akers A, Jarzembowski JA, Johnson CT, Lieberman RW, Dalton VK) J Perinat Med 2007;35(1):36-42 PMID: 17313308 SCOPUS ID: 2-s2.0-33847212443 02/23/2007       5 Citations
  • Squamous cell carcinoma arising in a pediatric intra- and paravertebral teratoma. (Jarzembowski JA, Ruiz RE) Pediatr Dev Pathol 2006 Jul-Aug;9(4):328-31 PMID: 16944983 SCOPUS ID: 2-s2.0-33747893363 09/02/2006       2 Citations
  • Pediatric sex cord-stromal tumor with composite morphology: a case report. (Jarzembowski JA, Lieberman RW) Pediatr Dev Pathol 2005 Nov-Dec;8(6):680-4 PMID: 16222477 SCOPUS ID: 2-s2.0-29244454271 10/14/2005       2 Citations
  • Polarizable placental particles: a case study and brief review of the literature. (Jarzembowski JA, McHugh J, Lieberman RW) Arch Pathol Lab Med 2004 Jun;128(6):675-7 PMID: 15163231 SCOPUS ID: 2-s2.0-4844227617 05/28/2004       1 Citation
  • Calcium ionophore upregulation of AUUUA-specific binding protein activity is contemporaneous with granulocyte macrophage colony-stimulating factor messenger RNA stabilization in AML14.3D10 cells. (Ruth JH, Esnault S, Jarzembowski JA, Malter JS) Am J Respir Cell Mol Biol 1999 Nov;21(5):621-8 PMID: 10536121 SCOPUS ID: 2-s2.0-0033220421 10/28/1999       18 Citations
  • The 5'-untranslated region of GM-CSF mRNA suppresses translational repression mediated by the 3' adenosine-uridine-rich element and the poly(A) tail. (Jarzembowski JA, Rajagopalan LE, Shin HC, Malter JS) Nucleic Acids Res 1999 Sep 15;27(18):3660-6 PMID: 10471734 PMCID: PMC148620 SCOPUS ID: 2-s2.0-0033568389 09/03/1999       12 Citations
  • Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs. (Esnault S, Jarzembowski JA, Malter JS) Proc Assoc Am Physicians 1998 Nov-Dec;110(6):575-84 PMID: 9824539 SCOPUS ID: 2-s2.0-0031771622 11/21/1998       19 Citations
  • hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNA. (Rajagopalan LE, Westmark CJ, Jarzembowski JA, Malter JS) Nucleic Acids Res 1998 Jul 15;26(14):3418-23 PMID: 9649628 PMCID: PMC147701 SCOPUS ID: 2-s2.0-0032528304 07/03/1998       75 Citations
  • Cytoplasmic fate of eukaryotic mRNA: identification and characterization of AU-binding proteins. (Jarzembowski JA, Malter JS) Prog Mol Subcell Biol 1997;18:141-72 PMID: 8994264 SCOPUS ID: 2-s2.0-0030635753 01/01/1997       15 Citations
  • Last update: 10/02/2019
    jenkins-FCD Prod-388 89e904233d719332173309c68ab82b0b2a78a3a7