Medical College of Wisconsin
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Kevin R. Regner MD

Kevin R. Regner MD

Chief, Associate Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Nephrology
Program: Administration

Member of the Cardiovascular Center
Member of the Genomic Sciences and Precision Medicine Center (GSPMC)

Research Experience

  • Hemofiltration
  • Kidney Failure, Chronic
  • Kidney Tubular Necrosis, Acute
  • Kidney Tubules, Proximal
  • Renal Replacement Therapy
  • Publications

  • MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension. (Liu Y, Usa K, Wang F, Liu P, Geurts AM, Li J, Williams AM, Regner KR, Kong Y, Liu H, Nie J, Liang M) J Am Soc Nephrol 2018 Oct;29(10):2518-2528 PMID: 30049682 PMCID: PMC6171279 07/28/2018       1 Citations
  • Urinary exosomal expression of activator of G protein signaling 3 in polycystic kidney disease. (Keri KC, Regner KR, Dall AT, Park F) BMC Res Notes 2018 Jun 07;11(1):359 PMID: 29880041 PMCID: PMC5992714 06/09/2018    
  • Artificial intelligence, physiological genomics, and precision medicine. (Williams AM, Liu Y, Regner KR, Jotterand F, Liu P, Liang M) Physiol Genomics 2018 Apr 01;50(4):237-243 PMID: 29373082 PMCID: PMC5966805 01/27/2018       2 Citations
  • Tissue-Specific MicroRNA Expression Patterns in Four Types of Kidney Disease. (Baker MA, Davis SJ, Liu P, Pan X, Williams AM, Iczkowski KA, Gallagher ST, Bishop K, Regner KR, Liu Y, Liang M) J Am Soc Nephrol 2017 Oct;28(10):2985-2992 PMID: 28663230 PMCID: PMC5619963 07/01/2017       11 Citations
  • TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury. (Pressly JD, Hama T, Brien SO, Regner KR, Park F) Sci Rep 2017 03 03;7:43196 PMID: 28256593 PMCID: PMC5335694 03/04/2017       2 Citations
  • Outcome analysis of continuous intraoperative renal replacement therapy in the highest acuity liver transplant recipients: A single-center experience. (Zimmerman MA, Selim M, Kim J, Regner K, Saeian K, Zanowski S, Martin A, Connolly LA, Lauer KK, Woehlck HJ, Hong JC) Surgery 2017 05;161(5):1279-1286 PMID: 28011008 12/25/2016       4 Citations
  • Kidney Injury in Liver Disease. (Regner KR, Singbartl K) Crit Care Clin 2016 Jul;32(3):343-55 PMID: 27339675 06/25/2016       6 Citations
  • Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury. (Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ) J Am Soc Nephrol 2015 Oct;26(10):2460-9 PMID: 25644108 PMCID: PMC4587700 02/04/2015       10 Citations
  • Activator of G-protein Signaling 3 Controls Renal Epithelial Cell Survival and ERK5 Activation. (Rasmussen SA, Kwon M, Pressly JD, Blumer JB, Regner KR, Park F) J Mol Signal 2015 Nov 27;10:6 PMID: 27096004 PMCID: PMC4831271 01/01/2015    
  • Localization and expression profile of Group I and II Activators of G-protein Signaling in the kidney. (Lenarczyk M, Pressly JD, Arnett J, Regner KR, Park F) J Mol Histol 2015 Apr;46(2):123-36 PMID: 25533045 PMCID: PMC4369180 12/24/2014       7 Citations
  • G-protein βγ subunit dimers modulate kidney repair after ischemia-reperfusion injury in rats. (White SM, North LM, Haines E, Goldberg M, Sullivan LM, Pressly JD, Weber DS, Park F, Regner KR) Mol Pharmacol 2014 Oct;86(4):369-77 PMID: 25028481 PMCID: PMC4164983 07/17/2014       7 Citations
  • De novo expression of sodium-glucose cotransporter SGLT2 in Bowman's capsule coincides with replacement of parietal epithelial cell layer with proximal tubule-like epithelium. (Tabatabai NM, North PE, Regner KR, Kumar SN, Duris CB, Blodgett AB) J Membr Biol 2014 Aug;247(8):675-83 PMID: 24906870 PMCID: PMC4117812 06/08/2014       2 Citations
  • Genetic susceptibility and loss of Nr4a1 enhances macrophage-mediated renal injury in CKD. (Westbrook L, Johnson AC, Regner KR, Williams JM, Mattson DL, Kyle PB, Henegar JR, Garrett MR) J Am Soc Nephrol 2014 Nov;25(11):2499-510 PMID: 24722447 PMCID: PMC4214519 04/12/2014       10 Citations
  • Phenytoin removal by continuous venovenous hemofiltration. (Oltrogge KM, Peppard WJ, Saleh M, Regner KR, Herrmann DJ) Ann Pharmacother 2013 Sep;47(9):1218-22 PMID: 24259740 11/22/2013       6 Citations
  • Genetic variants in Arhgef11 are associated with kidney injury in the Dahl salt-sensitive rat. (Williams JM, Johnson AC, Stelloh C, Dreisbach AW, Franceschini N, Regner KR, Townsend RR, Roman RJ, Garrett MR) Hypertension 2012 Nov;60(5):1157-68 PMID: 22987919 PMCID: PMC3505884 09/19/2012       15 Citations
  • Increased susceptibility to kidney injury by transfer of genomic segment from SHR onto Dahl S genetic background. (Regner KR, Harmon AC, Williams JM, Stelloh C, Johnson AC, Kyle PB, Lerch-Gaggl A, White SM, Garrett MR) Physiol Genomics 2012 Jun 15;44(12):629-37 PMID: 22548739 PMCID: PMC3426430 05/03/2012       6 Citations
  • Urinary interleukin-18 and urinary neutrophil gelatinase-associated lipocalin predict acute kidney injury following pulmonary valve replacement prior to serum creatinine. (Buelow MW, Dall A, Regner K, Weinberg C, Bartz PJ, Sowinski J, Rudd N, Katzmark L, Tweddell JS, Earing MG) Congenit Heart Dis 2012 Sep-Oct;7(5):441-7 PMID: 22537138 04/28/2012       16 Citations
  • Editorial Comment to Renoprotective effect of erythropoietin in ischemia/reperfusion injury: possible roles of the Akt/endothelial nitric oxide synthase-dependent pathway. (Regner KR) Int J Urol 2012 Mar;19(3):256 PMID: 22151694 12/14/2011    
  • Dual role of microsomal prostaglandin E synthase 1 in chronic kidney disease. (Regner KR) Hypertension 2012 Jan;59(1):12-3 PMID: 22106400 11/23/2011       4 Citations
  • Role of medullary blood flow in the pathogenesis of renal ischemia-reperfusion injury. (Regner KR, Roman RJ) Curr Opin Nephrol Hypertens 2012 Jan;21(1):33-8 PMID: 22080855 PMCID: PMC3612396 11/15/2011       41 Citations
  • Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. (Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F) FASEB J 2011 Jun;25(6):1844-55 PMID: 21343176 PMCID: PMC3101034 02/24/2011       26 Citations
  • 20-HETE in acute kidney injury. (Roman RJ, Akbulut T, Park F, Regner KR) Kidney Int 2011 Jan;79(1):10-3 PMID: 21157458 PMCID: PMC3146060 12/16/2010       9 Citations
  • Protective effect of Lifor solution in experimental renal ischemia-reperfusion injury. (Regner KR, Nilakantan V, Ryan RP, Mortensen J, White SM, Shames BD, Roman RJ) J Surg Res 2010 Dec;164(2):e291-7 PMID: 20888590 PMCID: PMC2991539 10/05/2010       21 Citations
  • Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection. (Ionova IA, Vásquez-Vivar J, Cooley BC, Khanna AK, Whitsett J, Herrnreiter A, Migrino RQ, Ge ZD, Regner KR, Channon KM, Alp NJ, Pieper GM) Am J Physiol Heart Circ Physiol 2010 Jul;299(1):H88-96 PMID: 20418482 PMCID: PMC2904123 04/27/2010       6 Citations
  • Heterogeneous stock rats: a new model to study the genetics of renal phenotypes. (Solberg Woods LC, Stelloh C, Regner KR, Schwabe T, Eisenhauer J, Garrett MR) Am J Physiol Renal Physiol 2010 Jun;298(6):F1484-91 PMID: 20219828 PMCID: PMC2886820 03/12/2010       14 Citations
  • 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. (Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F) Am J Physiol Renal Physiol 2009 Sep;297(3):F662-70 PMID: 19570883 PMCID: PMC2739708 07/03/2009       37 Citations
  • MnTMPyP, a cell-permeant SOD mimetic, reduces oxidative stress and apoptosis following renal ischemia-reperfusion. (Liang HL, Hilton G, Mortensen J, Regner K, Johnson CP, Nilakantan V) Am J Physiol Renal Physiol 2009 Feb;296(2):F266-76 PMID: 19091787 PMCID: PMC2643863 12/19/2008       50 Citations
  • Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury. (Regner KR, Zuk A, Van Why SK, Shames BD, Ryan RP, Falck JR, Manthati VL, McMullen ME, Ledbetter SR, Roman RJ) Kidney Int 2009 Mar;75(5):511-7 PMID: 19052533 PMCID: PMC2643317 12/05/2008       50 Citations
  • Obstructive renal failure from malpositioned urinary catheter. (El-Zoghby ZM, Regner KR, Regner DM, Haugen EN) Kidney Int 2008 Jun;73(11):1330 PMID: 18480860 05/16/2008       1 Citations
  • Acute renal failure after cardiac surgery for carcinoid heart disease: incidence, risk factors, and prognosis. (Regner KR, Connolly HM, Schaff HV, Albright RC) Am J Kidney Dis 2005 May;45(5):826-32 PMID: 15861347 04/30/2005       22 Citations
  • 35-year-old woman with cough, fever, and anorexia. (Ensminger SA, Regner KR, Froehling DA) Mayo Clin Proc 2003 Jun;78(6):753-6 PMID: 12934787 08/26/2003    
  • Serial measurement of serum tryptase in angiotensin-converting enzyme inhibitor-associated angioedema. (Regner KR, Riegert-Johnson DL, Volcheck GW) Mayo Clin Proc 2003 May;78(5):655-6 PMID: 12744557 05/15/2003    
  • Angiotensin II blockade reduces radiation-induced proliferation in experimental radiation nephropathy. (Moulder JE, Fish BL, Regner KR, Cohen EP) Radiat Res 2002 Apr;157(4):393-401 PMID: 11893241 03/15/2002       22 Citations
  • Retinoic acid exacerbates experimental radiation nephropathy. (Moulder JE, Fish BL, Regner KR, Cohen EP, Raife TJ) Radiat Res 2002 Feb;157(2):199-203 PMID: 11835684 02/12/2002       17 Citations
  • Stenotic glomerulotubular necks in radiation nephropathy. (Cohen EP, Regner K, Fish BL, Moulder JE) J Pathol 2000 Mar;190(4):484-8 PMID: 10699999 03/04/2000       15 Citations
  • Last update: 09/04/2018
    jenkins-FCD Prod-300 626508253d14e4184314fb9f66322a03a5906796