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Gopinath Tata PhD

Gopinath Tata PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Research

View Curriculum Vitae

Publications (57)

  • A pH-sensitive motif in an outer membrane protein activates bacterial membrane vesicle production. (Dehinwal R, Gopinath T, Smith RD, Ernst RK, Schifferli DM, Waldor MK, Marassi FM) Nat Commun 2024 Aug 13;15(1):6958 PMID: 39138228 PMCID: PMC11322160 SCOPUS ID: 2-s2.0-85201246120 08/14/2024    
  • Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite. (Gopinath T, Shin K, Tian Y, Im W, Struppe J, Perrone B, Hassan A, Marassi FM) J Struct Biol 2024 Mar;216(1):108061 PMID: 38185342 PMCID: PMC10939839 SCOPUS ID: 2-s2.0-85182378487 01/08/2024       2 Citations
  • PHRONESIS: A One-Shot Approach for Sequential Assignment of Protein Resonances by Ultrafast MAS Solid-State NMR Spectroscopy. (Gopinath T, Manu VS, Weber DK, Veglia G) Chemphyschem 2022 Jul 05;23(13):e202200127 PMID: 35499980 PMCID: PMC9400877 SCOPUS ID: 2-s2.0-85130396254 05/03/2022       4 Citations
  • A kink in DWORF helical structure controls the activation of the sarcoplasmic reticulum Ca2+-ATPase. (Reddy UV, Weber DK, Wang S, Larsen EK, Gopinath T, De Simone A, Robia S, Veglia G) Structure 2022 Mar 03;30(3):360-370.e6 PMID: 34875216 PMCID: PMC8897251 SCOPUS ID: 2-s2.0-85123018206 12/08/2021       12 Citations
  • Structural basis for sarcolipin's regulation of muscle thermogenesis by the sarcoplasmic reticulum Ca2+-ATPase. (Wang S, Gopinath T, Larsen EK, Weber DK, Walker C, Uddigiri VR, Mote KR, Sahoo SK, Periasamy M, Veglia G) Sci Adv 2021 Nov 26;7(48):eabi7154 PMID: 34826239 PMCID: PMC8626070 SCOPUS ID: 2-s2.0-85120338258 11/27/2021       9 Citations
  • Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation. (Weber DK, Reddy UV, Wang S, Larsen EK, Gopinath T, Gustavsson MB, Cornea RL, Thomas DD, De Simone A, Veglia G) Elife 2021 May 12;10 PMID: 33978571 PMCID: PMC8184213 SCOPUS ID: 2-s2.0-85108020453 05/13/2021       20 Citations
  • Solid-State NMR of Membrane Proteins in Lipid Bilayers: To Spin or Not To Spin? (Gopinath T, Weber D, Wang S, Larsen E, Veglia G) Acc Chem Res 2021 Mar 16;54(6):1430-1439 PMID: 33655754 PMCID: PMC11457538 SCOPUS ID: 2-s2.0-85102964601 03/04/2021       19 Citations
  • Simultaneous acquisition of multiple fast MAS solid-state NMR experiments via orphan spin polarization (Gopinath T, Veglia G) Annual Reports on NMR Spectroscopy January 2021;102:247-268 SCOPUS ID: 2-s2.0-85099955760 01/01/2021       5 Citations
  • Hybridizing isotropic and anisotropic solid-state NMR restraints for membrane protein structure determination (Weber DK, Larsen EK, Gopinath T, Veglia G) Solid-State NMR: Applications in biomembrane structure 3 December 2020:12.1-12.21 SCOPUS ID: 2-s2.0-85180138686 12/03/2020       2 Citations
  • Molecular Mechanism for the Suppression of Alpha Synuclein Membrane Toxicity by an Unconventional Extracellular Chaperone. (Ahmed R, Huang J, Weber DK, Gopinath T, Veglia G, Akimoto M, Khondker A, Rheinstädter MC, Huynh V, Wylie RG, Bozelli JC Jr, Epand RM, Melacini G) J Am Chem Soc 2020 May 27;142(21):9686-9699 PMID: 32383602 SCOPUS ID: 2-s2.0-85085657558 05/10/2020       19 Citations
  • Multi-receiver solid-state NMR using polarization optimized experiments (POE) at ultrafast magic angle spinning. (Gopinath T, Weber DK, Veglia G) J Biomol NMR 2020 May;74(4-5):267-285 PMID: 32333193 PMCID: PMC7236978 SCOPUS ID: 2-s2.0-85083825531 04/26/2020       12 Citations
  • Proton-detected polarization optimized experiments (POE) using ultrafast magic angle spinning solid-state NMR: Multi-acquisition of membrane protein spectra. (Gopinath T, Veglia G) J Magn Reson 2020 Jan;310:106664 PMID: 31837552 PMCID: PMC7003683 SCOPUS ID: 2-s2.0-85076263034 12/15/2019       10 Citations
  • Improving the quality of oriented membrane protein spectra using heat-compensated separated local field experiments. (Wang S, Gopinath T, Veglia G) J Biomol NMR 2019 Nov;73(10-11):617-624 PMID: 31463642 PMCID: PMC6861693 SCOPUS ID: 2-s2.0-85071423652 08/30/2019       7 Citations
  • Intrinsically disordered HAX-1 regulates Ca2+ cycling by interacting with lipid membranes and the phospholamban cytoplasmic region. (Larsen EK, Weber DK, Wang S, Gopinath T, Blackwell DJ, Dalton MP, Robia SL, Gao J, Veglia G) Biochim Biophys Acta Biomembr 2020 Jan 01;1862(1):183034 PMID: 31400305 PMCID: PMC6899184 SCOPUS ID: 2-s2.0-85070875364 08/11/2019       11 Citations
  • T2* weighted Deconvolution of NMR Spectra: Application to 2D Homonuclear MAS Solid-State NMR of Membrane Proteins. (V S M, Gopinath T, Wang S, Veglia G) Sci Rep 2019 Jun 03;9(1):8225 PMID: 31160739 PMCID: PMC6546711 SCOPUS ID: 2-s2.0-85067190230 06/05/2019       9 Citations
  • Cysteine-ethylation of tissue-extracted membrane proteins as a tool to detect conformational states by solid-state NMR spectroscopy. (Weber DK, Bader T, Larsen EK, Wang S, Gopinath T, Distefano M, Veglia G) Methods Enzymol 2019;621:281-304 PMID: 31128784 PMCID: PMC7418180 SCOPUS ID: 2-s2.0-85062440806 05/28/2019       3 Citations
  • More than a Liquid Junction: Effect of Stirring, Flow Rate, and Inward and Outward Electrolyte Diffusion on Reference Electrodes with Salt Bridges Contained in Nanoporous Glass. (Anderson EL, Lodge TP, Gopinath T, Veglia G, Bühlmann P) Anal Chem 2019 Jun 18;91(12):7698-7704 PMID: 31120239 SCOPUS ID: 2-s2.0-85067369984 05/24/2019       12 Citations
  • An intramembrane sensory circuit monitors sortase A-mediated processing of streptococcal adhesins. (Hall JW, Lima BP, Herbomel GG, Gopinath T, McDonald L, Shyne MT, Lee JK, Kreth J, Ross KF, Veglia G, Herzberg MC) Sci Signal 2019 May 07;12(580) PMID: 31064885 PMCID: PMC6662179 SCOPUS ID: 2-s2.0-85065780047 05/09/2019       15 Citations
  • A supramolecular synthon approach to design amorphous solid dispersions with exceptional physical stability. (Duggirala NK , Li J , Kumar NSK , Gopinath T , Suryanarayanan R ) Chem Commun (Camb) 2019 May 09;55(39):5551-5554 PMID: 30972394 SCOPUS ID: 2-s2.0-85065665479 04/12/2019       25 Citations
  • Hybridization of TEDOR and NCX MAS solid-state NMR experiments for simultaneous acquisition of heteronuclear correlation spectra and distance measurements. (Gopinath T, Wang S, Lee J, Aihara H, Veglia G) J Biomol NMR 2019 Apr;73(3-4):141-153 PMID: 30805819 PMCID: PMC6526076 SCOPUS ID: 2-s2.0-85062101242 02/26/2019       12 Citations
  • Probing membrane protein ground and conformationally excited states using dipolar- and J-coupling mediated MAS solid state NMR experiments. (Gopinath T, Veglia G) Methods 2018 Sep 15;148:115-122 PMID: 30012515 PMCID: PMC6428079 SCOPUS ID: 2-s2.0-85050178798 07/18/2018       15 Citations
  • Effects of the Arg9Cys and Arg25Cys mutations on phospholamban's conformational equilibrium in membrane bilayers. (Nelson SED, Ha KN, Gopinath T, Exline MH, Mascioni A, Thomas DD, Veglia G) Biochim Biophys Acta Biomembr 2018 Jun;1860(6):1335-1341 PMID: 29501609 PMCID: PMC6428084 SCOPUS ID: 2-s2.0-85045940567 03/05/2018       13 Citations
  • Application of paramagnetic relaxation enhancements to accelerate the acquisition of 2D and 3D solid-state NMR spectra of oriented membrane proteins. (Wang S, Gopinath T, Veglia G) Methods 2018 Apr 01;138-139:54-61 PMID: 29274874 PMCID: PMC5984106 SCOPUS ID: 2-s2.0-85044638879 12/25/2017       15 Citations
  • 1H-detected MAS solid-state NMR experiments enable the simultaneous mapping of rigid and dynamic domains of membrane proteins. (Gopinath T, Nelson SED, Veglia G) J Magn Reson 2017 Dec;285:101-107 PMID: 29173803 PMCID: PMC5764182 SCOPUS ID: 2-s2.0-85034835475 11/28/2017       15 Citations
  • Experimental Aspects of Polarization Optimized Experiments (POE) for Magic Angle Spinning Solid-State NMR of Microcrystalline and Membrane-Bound Proteins. (Gopinath T, Veglia G) Methods Mol Biol 2018;1688:37-53 PMID: 29151203 SCOPUS ID: 2-s2.0-85034815194 11/21/2017       11 Citations
  • Probing the Conformationally Excited States of Membrane Proteins via 1H-Detected MAS Solid-State NMR Spectroscopy. (Gopinath T, Nelson SED, Soller KJ, Veglia G) J Phys Chem B 2017 May 04;121(17):4456-4465 PMID: 28406633 SCOPUS ID: 2-s2.0-85020166925 04/14/2017       20 Citations
  • Probing Residue-Specific Water-Protein Interactions in Oriented Lipid Membranes via Solid-State NMR Spectroscopy (Dicke A, Gopinath T, Wang Y, Veglia G) Journal of Physical Chemistry B 27 October 2016;120(42):10959-10968 SCOPUS ID: 2-s2.0-84994048566 10/27/2016       5 Citations
  • Multiple acquisitions via sequential transfer of orphan spin polarization (MAeSTOSO): How far can we push residual spin polarization in solid-state NMR? (Gopinath T, Veglia G) J Magn Reson 2016 Jun;267:1-8 PMID: 27039168 PMCID: PMC4862926 SCOPUS ID: 2-s2.0-84962469033 04/04/2016       21 Citations
  • Allosteric Regulation of the M2 Protein from Influenza A by Cholesterol. (Veglia G, Nelson SE, Gopinath T) Biophys J 2016 Mar 29;110(6):1207-8 PMID: 27028630 PMCID: PMC4816697 SCOPUS ID: 2-s2.0-84964345817 03/31/2016       3 Citations
  • Orphan Spin Polarization: A Catalyst for High-Throughput Solid-State NMR Spectroscopy of Proteins (Gopinath T, Veglia G) Annual Reports on NMR Spectroscopy 2016;89:103-121 SCOPUS ID: 2-s2.0-84973572971 01/01/2016       12 Citations
  • Ca(2+) ATPase Conformational Transitions in Lipid Bilayers Mapped by Site-directed Ethylation and Solid-State NMR. (Vostrikov VV, Gustavsson M, Gopinath T, Mullen D, Dicke AA, Truong V, Veglia G) ACS Chem Biol 2016 Feb 19;11(2):329-34 PMID: 26650884 PMCID: PMC4993155 SCOPUS ID: 2-s2.0-84959343457 12/10/2015       5 Citations
  • Role of the Strength of Drug-Polymer Interactions on the Molecular Mobility and Crystallization Inhibition in Ketoconazole Solid Dispersions. (Mistry P, Mohapatra S, Gopinath T, Vogt FG, Suryanarayanan R) Mol Pharm 2015 Sep 08;12(9):3339-50 PMID: 26070543 SCOPUS ID: 2-s2.0-84941101436 06/14/2015       145 Citations
  • Multiple acquisition of magic angle spinning solid-state NMR experiments using one receiver: application to microcrystalline and membrane protein preparations. (Gopinath T, Veglia G) J Magn Reson 2015 Apr;253:143-53 PMID: 25797011 PMCID: PMC4399235 SCOPUS ID: 2-s2.0-84925368815 03/24/2015       16 Citations
  • Simultaneous acquisition of 2D and 3D solid-state NMR experiments for sequential assignment of oriented membrane protein samples. (Gopinath T, Mote KR, Veglia G) J Biomol NMR 2015 May;62(1):53-61 PMID: 25749871 PMCID: PMC4981477 SCOPUS ID: 2-s2.0-84940008370 03/10/2015       27 Citations
  • The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanism. (Cero C, Vostrikov VV, Verardi R, Severini C, Gopinath T, Braun PD, Sassano MF, Gurney A, Roth BL, Vulchanova L, Possenti R, Veglia G, Bartolomucci A) Structure 2014 Dec 02;22(12):1744-1753 PMID: 25456411 PMCID: PMC4353613 SCOPUS ID: 2-s2.0-84914156029 12/03/2014       49 Citations
  • Effects of naturally occurring arginine 14 deletion on phospholamban conformational dynamics and membrane interactions. (Vostrikov VV, Soller KJ, Ha KN, Gopinath T, Veglia G) Biochim Biophys Acta 2015 Jan;1848(1 Pt B):315-22 PMID: 25251363 PMCID: PMC4258429 SCOPUS ID: 2-s2.0-84979862534 09/25/2014       16 Citations
  • Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour. (Fusco G, De Simone A, Gopinath T, Vostrikov V, Vendruscolo M, Dobson CM, Veglia G) Nat Commun 2014 May 29;5:3827 PMID: 24871041 PMCID: PMC4046108 SCOPUS ID: 2-s2.0-84901812732 05/30/2014       344 Citations
  • Sensitivity and resolution enhancement of oriented solid-state NMR: application to membrane proteins. (Gopinath T, Mote KR, Veglia G) Prog Nucl Magn Reson Spectrosc 2013 Nov;75:50-68 PMID: 24160761 PMCID: PMC3850070 SCOPUS ID: 2-s2.0-84887104891 10/29/2013       31 Citations
  • Allosteric regulation of SERCA by phosphorylation-mediated conformational shift of phospholamban. (Gustavsson M, Verardi R, Mullen DG, Mote KR, Traaseth NJ, Gopinath T, Veglia G) Proc Natl Acad Sci U S A 2013 Oct 22;110(43):17338-43 PMID: 24101520 PMCID: PMC3808617 SCOPUS ID: 2-s2.0-84886402422 10/09/2013       109 Citations
  • Determination of structural topology of a membrane protein in lipid bilayers using polarization optimized experiments (POE) for static and MAS solid state NMR spectroscopy. (Mote KR, Gopinath T, Veglia G) J Biomol NMR 2013 Oct;57(2):91-102 PMID: 23963722 PMCID: PMC3883141 SCOPUS ID: 2-s2.0-84892924450 08/22/2013       34 Citations
  • Orphan spin operators enable the acquisition of multiple 2D and 3D magic angle spinning solid-state NMR spectra. (Gopinath T, Veglia G) J Chem Phys 2013 May 14;138(18):184201 PMID: 23676036 PMCID: PMC3663853 SCOPUS ID: 2-s2.0-84877989130 05/17/2013       36 Citations
  • The hybrid solution/solid-state NMR method for membrane protein structure determination (Veglia G, Traaseth NJ, Shi L, Verardi R, Gopinath T, Gustavsson M) Comprehensive Biophysics 2012;1:182-198 SCOPUS ID: 2-s2.0-84882738241 12/01/2012       8 Citations
  • 3D DUMAS: simultaneous acquisition of three-dimensional magic angle spinning solid-state NMR experiments of proteins. (Gopinath T, Veglia G) J Magn Reson 2012 Jul;220:79-84 PMID: 22698806 PMCID: PMC3487463 SCOPUS ID: 2-s2.0-84863312621 06/16/2012       42 Citations
  • Dual acquisition magic-angle spinning solid-state NMR-spectroscopy: simultaneous acquisition of multidimensional spectra of biomacromolecules. (Gopinath T, Veglia G) Angew Chem Int Ed Engl 2012 Mar 12;51(11):2731-5 PMID: 22311700 PMCID: PMC3513283 SCOPUS ID: 2-s2.0-84858058799 02/09/2012       74 Citations
  • Multidimensional oriented solid-state NMR experiments enable the sequential assignment of uniformly 15N labeled integral membrane proteins in magnetically aligned lipid bilayers. (Mote KR, Gopinath T, Traaseth NJ, Kitchen J, Gor'kov PL, Brey WW, Veglia G) J Biomol NMR 2011 Nov;51(3):339-46 PMID: 21976256 SCOPUS ID: 2-s2.0-80755133632 10/07/2011       34 Citations
  • Proton evolved local field solid-state nuclear magnetic resonance using Hadamard encoding: theory and application to membrane proteins. (Gopinath T, Mote KR, Veglia G) J Chem Phys 2011 Aug 21;135(7):074503 PMID: 21861572 PMCID: PMC3172034 SCOPUS ID: 2-s2.0-80052049670 08/25/2011       16 Citations
  • On the performance of spin diffusion NMR techniques in oriented solids: Prospects for resonance assignments and distance measurements from separated local field experiments (Traaseth NJ, Gopinath T, Veglia G) Journal of Physical Chemistry B 4 November 2010;114(43):13872-13880 SCOPUS ID: 2-s2.0-78549290654 11/04/2010       24 Citations
  • Improved resolution in dipolar NMR spectra using constant time evolution PISEMA experiment (Gopinath T, Veglia G) Chemical Physics Letters 9 July 2010;494(1-3):104-110 SCOPUS ID: 2-s2.0-77955926417 07/09/2010       9 Citations
  • Sensitivity enhancement of separated local field experiments: Application to membrane proteins (Gopinath T, Verardi R, Traaseth NJ, Veglia G) Journal of Physical Chemistry B 22 April 2010;114(15):5089-5095 SCOPUS ID: 2-s2.0-77951097482 04/22/2010       29 Citations
  • Sensitivity enhanced heteronuclear correlation spectroscopy in multidimensional solid-state NMR of oriented systems via chemical shift coherences. (Gopinath T, Traaseth NJ, Mote K, Veglia G) J Am Chem Soc 2010 Apr 21;132(15):5357-63 PMID: 20345172 PMCID: PMC3328406 SCOPUS ID: 2-s2.0-77951040333 03/30/2010       25 Citations
  • Implementation of Liouville Space Search Algorithm on a strongly dipolar Coupled Nuclear Spins (Gopinath T, Kumar A) "Future Directions of Magnetic Resonance" Special issue to commemorate the Platinum Jubilee of the Indian National Science Academy, Springer. 09/23/2009    
  • Sensitivity enhancement in static solid-state NMR experiments via single- and multiple-quantum dipolar coherences. (Gopinath T, Veglia G) J Am Chem Soc 2009 Apr 29;131(16):5754-6 PMID: 19351170 PMCID: PMC3481552 SCOPUS ID: 2-s2.0-70149102210 04/09/2009       49 Citations
  • Implementation of controlled phase shift gates and Collins version of Deutsch-Jozsa algorithm on a quadrupolar spin-7/2 nucleus using non-adiabatic geometric phases. (Gopinath T, Kumar A) J Magn Reson 2008 Aug;193(2):168-76 PMID: 18514557 SCOPUS ID: 2-s2.0-47549089647 06/03/2008       17 Citations
  • Hadamard NMR spectroscopy for two-dimensional quantum information processing and parallel search algorithms. (Gopinath T, Kumar A) J Magn Reson 2006 Dec;183(2):259-68 PMID: 17011221 SCOPUS ID: 2-s2.0-33750948417 10/03/2006       8 Citations
  • Geometric quantum computation using fictitious spin- 1 2 subspaces of strongly dipolar coupled nuclear spins (Gopinath T, Kumar A) Physical Review A - Atomic, Molecular, and Optical Physics 2006;73(2) SCOPUS ID: 2-s2.0-33144463302 01/01/2006       20 Citations
  • Programmable quantum-state discriminator by nuclear magnetic resonance (Gopinath T, Das R, Kumar A) Physical Review A - Atomic, Molecular, and Optical Physics April 2005;71(4) SCOPUS ID: 2-s2.0-26944487657 04/01/2005       10 Citations
  • Quantum information processing by NMR: Implementation of Inversion-on-equality gate, Parity gate and Fanout gate (Gopinath T, Das R, Kumar A ) Proc. Indian Natn. Sci. Acad. 70 A, 649-658 04/06/2004    
    • Last update: 08/16/2024