Medical College of Wisconsin
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Roger H. Johnson PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Research

Member of the Cancer Center


Publications (44)

  • Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. (Oleinik N, Kim J, Roth BM, Selvam SP, Gooz M, Johnson RH, Lemasters JJ, Ogretmen B) Sci Adv 2019 09;5(9):eaax1978 PMID: 31535025 PMCID: PMC6739097 09/20/2019       3 Citations
  • Optical computed tomography for spatially isotropic four-dimensional imaging of live single cells. (Kelbauskas L, Shetty R, Cao B, Wang KC, Smith D, Wang H, Chao SH, Gangaraju S, Ashcroft B, Kritzer M, Glenn H, Johnson RH, Meldrum DR) Sci Adv 2017 12;3(12):e1602580 PMID: 29226240 PMCID: PMC5721812 SCOPUS ID: 2-s2.0-85041821749 12/12/2017       4 Citations
  • A platform for high-throughput bioenergy production phenotype characterization in single cells. (Kelbauskas L, Glenn H, Anderson C, Messner J, Lee KB, Song G, Houkal J, Su F, Zhang L, Tian Y, Wang H, Bussey K, Johnson RH, Meldrum DR) Sci Rep 2017 03 28;7:45399 PMID: 28349963 PMCID: PMC5368665 SCOPUS ID: 2-s2.0-85016622569 03/30/2017       6 Citations
  • Characterization and comparison of three microfabrication methods to generate out-of-plane microvortices for single cell rotation and 3D imaging (Shetty RM, Myers JR, Sreenivasulu M, Teller W, Vela J, Houkal J, Chao SH, Johnson RH, Kelbauskas L, Wang H, Meldrum DR) Journal of Micromechanics and Microengineering January 2017;27(1) SCOPUS ID: 2-s2.0-85005949723 01/01/2017    
  • Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. (Nandakumar V, Hansen N, Glenn HL, Han JH, Helland S, Hernandez K, Senechal P, Johnson RH, Bussey KJ, Meldrum DR) Sci Rep 2016 08 09;6:30593 PMID: 27503568 PMCID: PMC4977554 SCOPUS ID: 2-s2.0-84981290391 08/10/2016       3 Citations
  • Sensitizing cancer cells to TRAIL-induced death by micellar delivery of mitoxantrone. (Grandhi TS, Potta T, Taylor DJ, Tian Y, Johnson RH, Meldrum DR, Rege K) Nanomedicine (Lond) 2014;9(12):1775-88 PMID: 24195660 SCOPUS ID: 2-s2.0-84908222476 11/08/2013       5 Citations
  • Integrated metagenomic and metatranscriptomic analyses of microbial communities in the meso- and bathypelagic realm of north pacific ocean. (Wu J, Gao W, Johnson RH, Zhang W, Meldrum DR) Mar Drugs 2013 Oct 11;11(10):3777-801 PMID: 24152557 PMCID: PMC3826135 SCOPUS ID: 2-s2.0-84887078104 10/25/2013       16 Citations
  • Single-cell analysis reveals early manifestation of cancerous phenotype in pre-malignant esophageal cells. (Wang J, Shi X, Johnson RH, Kelbauskas L, Zhang W, Meldrum DR) PLoS One 2013;8(10):e75365 PMID: 24116039 PMCID: PMC3792915 10/12/2013       110 Citations
  • On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate (Mei Q, Johnson RH, Wei X, Su F, Liu Y, Kelbauskas L, Lindsay S, Meldrum DR, Yan H) Nano Research October 2013;6(10):712-719 SCOPUS ID: 2-s2.0-84886096990 10/01/2013    
  • A physical sciences network characterization of non-tumorigenic and metastatic cells. (Physical Sciences - Oncology Centers Network, Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH) Sci Rep 2013;3:1449 PMID: 23618955 PMCID: PMC3636513 SCOPUS ID: 2-s2.0-84878282427 04/27/2013       93 Citations
  • Using fluorine-containing amphiphilic random copolymers to manipulate the quantum yields of aggregation-induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging. (Lu H, Su F, Mei Q, Tian Y, Tian W, Johnson RH, Meldrum DR) J Mater Chem 2012 May 01;22(19):9890-9900 PMID: 23397360 PMCID: PMC3565462 02/12/2013    
  • Surface tension-controlled three-dimensional water molds: Theory and applications (Goff CM, Chao SH, Johnson RH, Meldrum DR) Microfluidics and Nanofluidics December 2012;13(6):891-897 SCOPUS ID: 2-s2.0-84871761633 12/01/2012    
  • Simulation and experimental characterization of microscopically accessible hydrodynamic microvortices (Zhang W, Frakes DH, Babiker H, Chao SH, Youngbull C, Johnson RH, Meldrum DR) Micromachines 2012;3(2):529-541 SCOPUS ID: 2-s2.0-84874450706 12/01/2012    
  • Using fluorine-containing amphiphilic random copolymers to manipulate the quantum yields of aggregation-induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging (Lu H, Su F, Mei Q, Tian Y, Tian W, Johnson RH, Meldrum DR) Journal of Materials Chemistry 21 May 2012;22(19):9890-9900 SCOPUS ID: 2-s2.0-84860378382 05/21/2012    
  • Method for physiologic phenotype characterization at the single-cell level in non-interacting and interacting cells. (Kelbauskas L, Ashili SP, Houkal J, Smith D, Mohammadreza A, Lee KB, Forrester J, Kumar A, Anis YH, Paulson TG, Youngbull CA, Tian Y, Holl MR, Johnson RH, Meldrum DR) J Biomed Opt 2012 Mar;17(3):037008 PMID: 22502580 PMCID: PMC3602818 SCOPUS ID: 2-s2.0-84864922062 04/17/2012       17 Citations
  • Nanostructured oxygen sensor--using micelles to incorporate a hydrophobic platinum porphyrin. (Su F, Alam R, Mei Q, Tian Y, Youngbull C, Johnson RH, Meldrum DR) PLoS One 2012;7(3):e33390 PMID: 22457758 PMCID: PMC3310867 SCOPUS ID: 2-s2.0-84863353677 03/30/2012       36 Citations
  • A series of poly[N-(2-hydroxypropyl)methacrylamide] copolymers with anthracene-derived fluorophores showing aggregation-induced emission properties for bioimaging. (Lu H, Su F, Mei Q, Zhou X, Tian Y, Tian W, Johnson RH, Meldrum DR) J Polym Sci A Polym Chem 2012 Mar 01;50(5):890-899 PMID: 22287826 PMCID: PMC3266372 01/31/2012    
  • Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations. (Nandakumar V, Kelbauskas L, Hernandez KF, Lintecum KM, Senechal P, Bussey KJ, Davies PC, Johnson RH, Meldrum DR) PLoS One 2012;7(1):e29230 PMID: 22242161 PMCID: PMC3252316 SCOPUS ID: 2-s2.0-84855387742 01/14/2012       38 Citations
  • A statistical framework for multiparameter analysis at the single-cell level. (Torres-García W, Ashili S, Kelbauskas L, Johnson RH, Zhang W, Runger GC, Meldrum DR) Mol Biosyst 2012 Mar;8(3):804-17 PMID: 22222464 SCOPUS ID: 2-s2.0-84863125256 01/10/2012       2 Citations
  • A new highly selective fluorescent K+ sensor. (Zhou X, Su F, Tian Y, Youngbull C, Johnson RH, Meldrum DR) J Am Chem Soc 2011 Nov 23;133(46):18530-3 PMID: 22026580 PMCID: PMC3223084 SCOPUS ID: 2-s2.0-83055161605 10/27/2011       110 Citations
  • An FRET-based ratiometric chemosensor for in vitro cellular fluorescence analyses of pH. (Zhou X, Su F, Lu H, Senechal-Willis P, Tian Y, Johnson RH, Meldrum DR) Biomaterials 2012 Jan;33(1):171-80 PMID: 21982292 PMCID: PMC3208745 SCOPUS ID: 2-s2.0-82855172094 10/11/2011       131 Citations
  • Platinum (II) Porphyrin-Containing Thermoresponsive Poly(N-isopropylacrylamide) Copolymer as Fluorescence Dual Oxygen and Temperature Sensor. (Zhou X, Su F, Tian Y, Johnson RH, Meldrum DR) Sens Actuators B Chem 2011 Nov 28;159(1):135-141 PMID: 21927540 PMCID: PMC3171833 SCOPUS ID: 2-s2.0-80052314241 09/20/2011    
  • Triazacryptand-based fluorescent sensors for extracellular and intracellular K+ sensing. (Zhou X, Su F, Gao W, Tian Y, Youngbull C, Johnson RH, Meldrum DR) Biomaterials 2011 Nov;32(33):8574-83 PMID: 21855134 PMCID: PMC3177004 SCOPUS ID: 2-s2.0-80052970870 08/23/2011       36 Citations
  • Quantitative single-cell gene expression measurements of multiple genes in response to hypoxia treatment. (Zeng J, Wang J, Gao W, Mohammadreza A, Kelbauskas L, Zhang W, Johnson RH, Meldrum DR) Anal Bioanal Chem 2011 Jul;401(1):3-13 PMID: 21614642 SCOPUS ID: 2-s2.0-79960555292 05/27/2011       10 Citations
  • Stability of DNA origami nanoarrays in cell lysate. (Mei Q, Wei X, Su F, Liu Y, Youngbull C, Johnson R, Lindsay S, Yan H, Meldrum D) Nano Lett 2011 Apr 13;11(4):1477-82 PMID: 21366226 PMCID: PMC3319871 SCOPUS ID: 2-s2.0-79954497718 03/04/2011       194 Citations
  • Integrative analysis of transcriptomic and proteomic data of Shewanella oneidensis: missing value imputation using temporal datasets. (Torres-García W, Brown SD, Johnson RH, Zhang W, Runger GC, Meldrum DR) Mol Biosyst 2011 Apr;7(4):1093-104 PMID: 21212895 SCOPUS ID: 2-s2.0-79952650377 01/08/2011       9 Citations
  • Quantitative characterization of preneoplastic progression using single-cell computed tomography and three-dimensional karyometry. (Nandakumar V, Kelbauskas L, Johnson R, Meldrum D) Cytometry A 2011 Jan;79(1):25-34 PMID: 21182180 PMCID: PMC3068856 SCOPUS ID: 2-s2.0-78650474099 12/25/2010       24 Citations
  • Influence of Matrices on Oxygen Sensing of Three Sensing Films with Chemically Conjugated Platinum Porphyrin Probes and Preliminary Application for Monitoring of Oxygen Consumption of Escherichia coli (E. coli). (Tian Y, Shumway BR, Gao W, Youngbull C, Holl MR, Johnson RH, Meldrum DR) Sens Actuators B Chem 2010 Oct 28;150(2):579-587 PMID: 21076638 PMCID: PMC2976577 SCOPUS ID: 2-s2.0-77958474975 11/16/2010    
  • A series of naphthalimide derivatives as intra and extracellular pH sensors. (Tian Y, Su F, Weber W, Nandakumar V, Shumway BR, Jin Y, Zhou X, Holl MR, Johnson RH, Meldrum DR) Biomaterials 2010 Oct;31(29):7411-22 PMID: 20619451 PMCID: PMC2940253 SCOPUS ID: 2-s2.0-77955276024 07/14/2010       95 Citations
  • Dually Fluorescent Sensing of pH and Dissolved Oxygen Using a Membrane Made from Polymerizable Sensing Monomers. (Tian Y, Shumway BR, Youngbull AC, Li Y, Jen AK, Johnson RH, Meldrum DR) Sens Actuators B Chem 2010 Jun 03;147(2):714-722 PMID: 20543884 PMCID: PMC2882062 SCOPUS ID: 2-s2.0-77953135783 06/15/2010    
  • An improved one-tube RT-PCR protocol for analyzing single-cell gene expression in individual mammalian cells. (Li Y, Thompson H, Hemphill C, Hong F, Forrester J, Johnson RH, Zhang W, Meldrum DR) Anal Bioanal Chem 2010 Jul;397(5):1853-9 PMID: 20490471 SCOPUS ID: 2-s2.0-77953811012 05/22/2010       13 Citations
  • Arterial tree morphometry (Johnson R) Handbook of Medical Image Processing and Analysis 2009:317-339 SCOPUS ID: 2-s2.0-84884777658 12/01/2009    
  • Integrative analysis of transcriptomic and proteomic data of Desulfovibrio vulgaris: a non-linear model to predict abundance of undetected proteins. (Torres-García W, Zhang W, Runger GC, Johnson RH, Meldrum DR) Bioinformatics 2009 Aug 01;25(15):1905-14 PMID: 19447782 PMCID: PMC2712339 SCOPUS ID: 2-s2.0-67650742246 05/19/2009       23 Citations
  • A simple derivation and analysis of a helical cone beam tomographic algorithm for long object imaging via a novel definition of region of interest. (Hu J, Tam K, Johnson RH) Phys Med Biol 2004 Jan 21;49(2):205-25 PMID: 15083667 SCOPUS ID: 2-s2.0-0942266356 04/16/2004       4 Citations
  • Improved iterative algorithm for sparse object reconstruction and its performance evaluation with Micro-CT data (Li M, Kudo H, Hu J, Johnson RH) IEEE Transactions on Nuclear Science June 2004;51(3 II):659-666 SCOPUS ID: 2-s2.0-3342925349 01/01/2004    
  • Pulmonary arterial morphometry from microfocal X-ray computed tomography. (Karau KL, Molthen RC, Dhyani A, Haworth ST, Hanger CC, Roerig DL, Johnson RH, Dawson CA) Am J Physiol Heart Circ Physiol 2001 Dec;281(6):H2747-56 PMID: 11709444 SCOPUS ID: 2-s2.0-0035658460 11/16/2001       41 Citations
  • Microfocal X-ray CT imaging and pulmonary arterial distensibility in excised rat lungs. (Karau KL, Johnson RH, Molthen RC, Dhyani AH, Haworth ST, Hanger CC, Roerig DL, Dawson CA) Am J Physiol Heart Circ Physiol 2001 Sep;281(3):H1447-57 PMID: 11514318 SCOPUS ID: 2-s2.0-0034829987 08/22/2001       47 Citations
  • An iterative approach to the beam hardening correction in cone beam CT. (Hsieh J, Molthen RC, Dawson CA, Johnson RH) Med Phys 2000 Jan;27(1):23-9 PMID: 10659734 SCOPUS ID: 2-s2.0-0033983855 02/05/2000       191 Citations
  • Automated detection of BB pixel clusters in digital fluoroscopic images. (Cho PS, Johnson RH) Phys Med Biol 1998 Sep;43(9):2677-83 PMID: 9755954 SCOPUS ID: 2-s2.0-0031663998 10/02/1998       14 Citations
  • Feldkamp and circle-and-line cone-beam reconstruction for 3D micro-CT of vascular networks. (Johnson RH, Hu H, Haworth ST, Cho PS, Dawson CA, Linehan JH) Phys Med Biol 1998 Apr;43(4):929-40 PMID: 9572516 SCOPUS ID: 2-s2.0-0031972279 05/08/1998       53 Citations
  • Cone-beam CT from width-truncated projections. (Cho PS, Rudd AD, Johnson RH) Comput Med Imaging Graph 1996 Jan-Feb;20(1):49-57 PMID: 8891422 SCOPUS ID: 2-s2.0-0029763942 01/01/1996       48 Citations
  • Cone-beam CT for radiotherapy applications. (Cho PS, Johnson RH, Griffin TW) Phys Med Biol 1995 Nov;40(11):1863-83 PMID: 8587937 SCOPUS ID: 2-s2.0-0029589221 11/01/1995       122 Citations
  • A new set of calibration standards for estimating the fat and mineral content of vertebrae via dual energy QCT. (Goodsitt MM, Johnson RH, Chesnut CH 3rd) Bone Miner 1991 Jun;13(3):217-33 PMID: 1863810 SCOPUS ID: 2-s2.0-0025753370 06/01/1991       14 Citations
  • 3-d display of magnetic resonance imaging of the spine (Nelson AC, Johnson RH, Kim Y, Haralick RM, Desoto LA, Anderson PA) Proceedings of SPIE - The International Society for Optical Engineering 8 June 1988;902:103-112 SCOPUS ID: 2-s2.0-84910967887 06/08/1988    
  • Last update: 08/07/2020
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