Medical College of Wisconsin
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Sridhar Rao MD, PhD

Sridhar Rao MD, PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Hematology/Oncology
Program: Hematology

Member of the Cancer Center


  • Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes. (Blinka S, Reimer MH Jr, Pulakanti K, Rao S) Cell Rep 2016 Sep 27;17(1):19-28 PMID: 27681417 09/30/2016
  • Identification of Transcribed Enhancers by Genome-Wide Chromatin Immunoprecipitation Sequencing. (Blinka S, Reimer MH Jr, Pulakanti K, Pinello L, Yuan GC, Rao S) Methods Mol Biol 2017;1468:91-109 PMID: 27662872 09/25/2016
  • The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9. (Fisher JB, Peterson J, Reimer M, Stelloh C, Pulakanti K, Gerbec ZJ, Abel AM, Strouse JM, Strouse C, McNulty M, Malarkannan S, Crispino JD, Milanovich S, Rao S) Leukemia 2016 Sep 30 PMID: 27554164 08/25/2016
  • Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy. (Rajasekaran K, Riese MJ, Rao S, Wang L, Thakar MS, Sentman CL, Malarkannan S) Front Immunol 2016;7:176 PMID: 27242783 PMCID: PMC4863891 06/01/2016
  • The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing. (Stelloh C, Reimer MH, Pulakanti K, Blinka S, Peterson J, Pinello L, Jia S, Roumiantsev S, Hessner MJ, Milanovich S, Yuan GC, Rao S) Epigenetics Chromatin 2016;9:14 PMID: 27087855 PMCID: PMC4832553 04/19/2016
  • CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes. (Zhang N, Zhi H, Curtis BR, Rao S, Jobaliya C, Poncz M, French DL, Newman PJ) Blood 2016 Feb 11;127(6):675-80 PMID: 26634302 PMCID: PMC4751021 12/05/2015
  • IQGAP1: insights into the function of a molecular puppeteer. (Abel AM, Schuldt KM, Rajasekaran K, Hwang D, Riese MJ, Rao S, Thakar MS, Malarkannan S) Mol Immunol 2015 Jun;65(2):336-49 PMID: 25733387 PMCID: PMC4480615 03/04/2015
  • Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation. (Sohni A, Bartoccetti M, Khoueiry R, Spans L, Vande Velde J, De Troyer L, Pulakanti K, Claessens F, Rao S, Koh KP) Mol Cell Biol 2015 Mar;35(6):1026-42 PMID: 25582196 PMCID: PMC4333094 01/15/2015
  • Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner. (Milanovich S, Peterson J, Allred J, Stelloh C, Rajasekaran K, Fisher J, Duncan SA, Malarkannan S, Rao S) Exp Hematol 2015 Jan;43(1):53-64.e1-8 PMID: 25246269 PMCID: PMC4268405 09/24/2014
  • A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targets. (Boheler KR, Bhattacharya S, Kropp EM, Chuppa S, Riordon DR, Bausch-Fluck D, Burridge PW, Wu JC, Wersto RP, Chan GC, Rao S, Wollscheid B, Gundry RL) Stem Cell Reports 2014 Jul 8;3(1):185-203 PMID: 25068131 PMCID: PMC4110789 07/30/2014
  • Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions. (Pulakanti K, Pinello L, Stelloh C, Blinka S, Allred J, Milanovich S, Kiblawi S, Peterson J, Wang A, Yuan GC, Rao S) Epigenetics 2013 Dec;8(12):1303-20 PMID: 24135681 PMCID: PMC3933491 10/19/2013
  • Embryonic Stem Cells: A Perfect Tool for Studying Mammalian Transcriptional Enhancers. (Rao S) J Stem Cell Res Ther 2012 Jul 5;Suppl 10 PMID: 24303336 PMCID: PMC3844140 07/05/2012
  • A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. (Gundry RL, Riordon DR, Tarasova Y, Chuppa S, Bhattacharya S, Juhasz O, Wiedemeier O, Milanovich S, Noto FK, Tchernyshyov I, Raginski K, Bausch-Fluck D, Tae HJ, Marshall S, Duncan SA, Wollscheid B, Wersto RP, Rao S, Van Eyk JE, Boheler KR) Mol Cell Proteomics 2012 Aug;11(8):303-16 PMID: 22493178 PMCID: PMC3412963 04/12/2012
  • Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. (Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A) Cell Stem Cell 2011 Feb 4;8(2):200-13 PMID: 21295276 PMCID: PMC3134318 02/08/2011
  • Differential roles of Sall4 isoforms in embryonic stem cell pluripotency. (Rao S, Zhen S, Roumiantsev S, McDonald LT, Yuan GC, Orkin SH) Mol Cell Biol 2010 Nov;30(22):5364-80 PMID: 20837710 PMCID: PMC2976381 09/15/2010
  • A protein interaction network for pluripotency of embryonic stem cells. (Wang J, Rao S, Chu J, Shen X, Levasseur DN, Theunissen TW, Orkin SH) Nature 2006 Nov 16;444(7117):364-8 PMID: 17093407 11/10/2006
  • Unraveling the transcriptional network controlling ES cell pluripotency. (Rao S, Orkin SH) Genome Biol 2006;7(8):230 PMID: 16942632 PMCID: PMC1779601 09/01/2006
  • Spi-1 and Spi-B control the expression of the Grap2 gene in B cells. (Garrett-Sinha LA, Hou P, Wang D, Grabiner B, Araujo E, Rao S, Yun TJ, Clark EA, Simon MC, Clark MR) Gene 2005 Jun 20;353(1):134-46 PMID: 15936902 06/07/2005
  • Spi-B can functionally replace PU.1 in myeloid but not lymphoid development. (Dahl R, Ramirez-Bergeron DL, Rao S, Simon MC) EMBO J 2002 May 1;21(9):2220-30 PMID: 11980719 PMCID: PMC125373 05/01/2002
  • PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. (Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC) Immunity 2001 Oct;15(4):545-55 PMID: 11672537 10/24/2001
  • PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1. (Garrett-Sinha LA, Dahl R, Rao S, Barton KP, Simon MC) Blood 2001 May 1;97(9):2908-12 PMID: 11313289 04/21/2001
  • The Ets factors PU.1 and Spi-B regulate the transcription in vivo of P2Y10, a lymphoid restricted heptahelical receptor. (Rao S, Garrett-Sinha LA, Yoon J, Simon MC) J Biol Chem 1999 Nov 26;274(48):34245-52 PMID: 10567398 11/24/1999
  • PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction. (Garrett-Sinha LA, Su GH, Rao S, Kabak S, Hao Z, Clark MR, Simon MC) Immunity 1999 Apr;10(4):399-408 PMID: 10229183 05/06/1999
  • SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1. (Rao S, Matsumura A, Yoon J, Simon MC) J Biol Chem 1999 Apr 16;274(16):11115-24 PMID: 10196196 04/10/1999
  • Gel-entrapment bioartificial liver therapy in galactosamine hepatitis. (Sielaff TD, Hu MY, Amiot B, Rollins MD, Rao S, McGuire B, Bloomer JR, Hu WS, Cerra FB) J Surg Res 1995 Jul;59(1):179-84 PMID: 7630125 07/01/1995
  • A technique for porcine hepatocyte harvest and description of differentiated metabolic functions in static culture. (Sielaff TD, Hu MY, Rao S, Groehler K, Olson D, Mann HJ, Remmel RP, Shatford RA, Amiot B, Hu WS) Transplantation 1995 May 27;59(10):1459-63 PMID: 7770934 05/27/1995
  • Last update: 10/19/2016