Medical College of Wisconsin
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Vera Tarakanova PhD

Vera Tarakanova PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Microbiology and Molecular Genetics

Member of the Cancer Center


  • Gammaherpesvirus targets peritoneal B-1 B cells for long-term latency. (Rekow MM, Darrah EJ, Mboko WP, Lange PT, Tarakanova VL) Virology 2016 May;492:140-4 PMID: 26945150 PMCID: PMC4826794 03/06/2016
  • Type I Interferon Counteracts Antiviral Effects of Statins in the Context of Gammaherpesvirus Infection. (Lange PT, Darrah EJ, Vonderhaar EP, Mboko WP, Rekow MM, Patel SB, Sidjanin DJ, Tarakanova VL) J Virol 2016;90(7):3342-54 PMID: 26739055 PMCID: PMC4794672 01/08/2016
  • Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus. (Mboko WP, Olteanu H, Ray A, Xin G, Darrah EJ, Kumar SN, Kulinski JM, Cui W, Dittel BN, Gauld SB, Tarakanova VL) J Virol 2015;90(6):2818-29 PMID: 26719266 PMCID: PMC4810652 01/01/2016
  • ATM facilitates mouse gammaherpesvirus reactivation from myeloid cells during chronic infection. (Kulinski JM, Darrah EJ, Broniowska KA, Mboko WP, Mounce BC, Malherbe LP, Corbett JA, Gauld SB, Tarakanova VL) Virology 2015 Sep;483:264-74 PMID: 26001649 PMCID: PMC4516584 05/24/2015
  • Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture. (Cieniewicz B, Dong Q, Li G, Forrest JC, Mounce BC, Tarakanova VL, van der Velden A, Krug LT) J Virol 2015 Jul;89(13):6562-74 PMID: 25855746 PMCID: PMC4468508 04/10/2015
  • Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells. (Mboko WP, Mounce BC, Emmer J, Darrah E, Patel SB, Tarakanova VL) J Virol 2014 Jun;88(12):6993-7004 PMID: 24719409 PMCID: PMC4054362 04/11/2014
  • Nitric oxide induces ataxia telangiectasia mutated (ATM) protein-dependent γH2AX protein formation in pancreatic β cells. (Oleson BJ, Broniowska KA, Schreiber KH, Tarakanova VL, Corbett JA) J Biol Chem 2014 Apr 18;289(16):11454-64 PMID: 24610783 PMCID: PMC4036281 03/13/2014
  • Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. (Mounce BC, Mboko WP, Kanack AJ, Tarakanova VL) J Virol 2014 Feb;88(4):2268-78 PMID: 24335310 PMCID: PMC3911555 12/18/2013
  • Regulation of antiviral CD8 T-cell responses. (Kulinski JM, Tarakanova VL, Verbsky J) Crit Rev Immunol 2013;33(6):477-88 PMID: 24266346 PMCID: PMC4729194 11/26/2013
  • Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells. (Sun X, Bristol JA, Iwahori S, Hagemeier SR, Meng Q, Barlow EA, Fingeroth JD, Tarakanova VL, Kalejta RF, Kenney SC) J Virol 2013 Sep;87(18):10126-38 PMID: 23843639 PMCID: PMC3754017 07/12/2013
  • Mouse gammaherpesvirus-68 infection acts as a rheostat to set the level of type I interferon signaling in primary macrophages. (Wood BM, Mboko WP, Mounce BC, Tarakanova VL) Virology 2013 Aug 15;443(1):123-33 PMID: 23706314 PMCID: PMC3703304 05/28/2013
  • A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages. (Mounce BC, Mboko WP, Bigley TM, Terhune SS, Tarakanova VL) J Virol 2013 Jul;87(13):7314-25 PMID: 23616648 PMCID: PMC3700300 04/26/2013
  • Reply to "testing for herpesvirus infection is essential in children with chromosomal-instability syndromes". (Kulinski JM, Tarakanova VL) J Virol 2013 Mar;87(6):3618 PMID: 23436902 PMCID: PMC3592165 02/26/2013
  • Modulation of B-cell tolerance by murine gammaherpesvirus 68 infection: requirement for Orf73 viral gene expression and follicular helper T cells. (Gauld SB, De Santis JL, Kulinski JM, McGraw JA, Leonardo SM, Ruder EA, Maier W, Tarakanova VL) Immunology 2013 Jun;139(2):197-204 PMID: 23311955 PMCID: PMC3647186 01/15/2013
  • Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection. (Kulinski JM, Leonardo SM, Mounce BC, Malherbe L, Gauld SB, Tarakanova VL) J Virol 2012 Dec;86(23):12826-37 PMID: 22993144 PMCID: PMC3497635 09/21/2012
  • Coordinate regulation of DNA damage and type I interferon responses imposes an antiviral state that attenuates mouse gammaherpesvirus type 68 replication in primary macrophages. (Mboko WP, Mounce BC, Wood BM, Kulinski JM, Corbett JA, Tarakanova VL) J Virol 2012 Jun;86(12):6899-912 PMID: 22496235 PMCID: PMC3393547 04/13/2012
  • Dynamic association of gammaherpesvirus DNA with core histone during de novo lytic infection of primary cells. (Mounce BC, Tsan FC, Kohler S, Cirillo LA, Tarakanova VL) Virology 2011 Dec 20;421(2):167-72 PMID: 22018782 PMCID: PMC3210866 10/25/2011
  • Gammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX. (Mounce BC, Tsan FC, Droit L, Kohler S, Reitsma JM, Cirillo LA, Tarakanova VL) Virology 2011 Nov 25;420(2):73-81 PMID: 21943826 PMCID: PMC3204369 09/29/2011
  • Conserved gammaherpesvirus kinase and histone variant H2AX facilitate gammaherpesvirus latency in vivo. (Tarakanova VL, Stanitsa E, Leonardo SM, Bigley TM, Gauld SB) Virology 2010 Sep 15;405(1):50-61 PMID: 20557919 06/19/2010
  • MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner. (Tarakanova VL, Molleston JM, Goodwin M, Virgin HW 4th) Virology 2010 Jan 20;396(2):323-8 PMID: 19910013 PMCID: PMC2805278 11/17/2009
  • Adenovirus E1A and E1B-19K proteins protect human hepatoma cells from transforming growth factor beta1-induced apoptosis. (Tarakanova VL, Wold WS) Virus Res 2010 Jan;147(1):67-76 PMID: 19854227 PMCID: PMC2794482 10/27/2009
  • Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. (Tarakanova VL, Leung-Pineda V, Hwang S, Yang CW, Matatall K, Basson M, Sun R, Piwnica-Worms H, Sleckman BP, Virgin HW 4th) Cell Host Microbe 2007 Jun 14;1(4):275-86 PMID: 18005708 PMCID: PMC2034359 11/17/2007
  • Murine gammaherpesvirus 68 genes both induce and suppress lymphoproliferative disease. (Tarakanova VL, Kreisel F, White DW, Virgin HW 4th) J Virol 2008 Jan;82(2):1034-9 PMID: 17977975 PMCID: PMC2224605 11/06/2007
  • Murine gammaherpesvirus 68 infection is associated with lymphoproliferative disease and lymphoma in BALB beta2 microglobulin-deficient mice. (Tarakanova VL, Suarez F, Tibbetts SA, Jacoby MA, Weck KE, Hess JL, Speck SH, Virgin HW 4th) J Virol 2005 Dec;79(23):14668-79 PMID: 16282467 PMCID: PMC1287585 11/12/2005
  • Adenovirus DNA binding protein inhibits SrCap-activated CBP and CREB-mediated transcription. (Xu X, Tarakanova V, Chrivia J, Yaciuk P) Virology 2003 Sep 1;313(2):615-21 PMID: 12954226 09/05/2003
  • Transforming growth factor beta1 receptor II is downregulated by E1A in adenovirus-infected cells. (Tarakanova VL, Wold WS) J Virol 2003 Sep;77(17):9324-36 PMID: 12915548 PMCID: PMC187388 08/14/2003
  • Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein. (Toth K, Tarakanova V, Doronin K, Ward P, Kuppuswamy M, Locke JE, Dawson JE, Kim HJ, Wold WS) Cancer Gene Ther 2003 Mar;10(3):193-200 PMID: 12637940 03/15/2003
  • Last update: 05/02/2016