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Publications indexed to the term Diabetes Mellitus, Experimental

4Visualization and quantification of mitochondrial structure in the endothelium of intact arteries. (Durand MJ, Ait-Aissa K, Levchenko V, Staruschenko A, Gutterman DD, Beyer AM) Cardiovasc Res 2019 08 01;115(10):1546-1556       2 Citations
3Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats. (Miller BS, Blumenthal SR, Shalygin A, Wright KD, Staruschenko A, Imig JD, Sorokin A) Diabetes 2018 11;67(11):2206-2212       3 Citations
2A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes. (Hye Khan MA, Kolb L, Skibba M, Hartmann M, Blöcher R, Proschak E, Imig JD) Diabetologia 2018 10;61(10):2235-2246       14 Citations
4Protective role of Trpc6 knockout in the progression of diabetic kidney disease. (Spires D, Ilatovskaya DV, Levchenko V, North PE, Geurts AM, Palygin O, Staruschenko A) Am J Physiol Renal Physiol 2018 10 01;315(4):F1091-F1097       17 Citations
4A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. (Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW Jr, Birnbaumer L, Staruschenko A) J Am Soc Nephrol 2018 07;29(7):1917-1927       34 Citations
1Rap1B promotes VEGF-induced endothelial permeability and is required for dynamic regulation of the endothelial barrier. (Lakshmikanthan S, Sobczak M, Li Calzi S, Shaw L, Grant MB, Chrzanowska-Wodnicka M) J Cell Sci 2018 01 10;131(1)       10 Citations
3Red/near infrared light stimulates release of an endothelium dependent vasodilator and rescues vascular dysfunction in a diabetes model. (Keszler A, Lindemer B, Weihrauch D, Jones D, Hogg N, Lohr NL) Free Radic Biol Med 2017 12;113:157-164       9 Citations
1Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia. (Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG) Biochim Biophys Acta Gen Subj 2017 Nov;1861(11 Pt A):2758-2765       13 Citations
1Cardiomyocyte GTP Cyclohydrolase 1 Protects the Heart Against Diabetic Cardiomyopathy. (Wu HE, Baumgardt SL, Fang J, Paterson M, Liu Y, Du J, Shi Y, Qiao S, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD) Sci Rep 2016 06 13;6:27925       13 Citations
1Exercise Training Attenuates Upregulation of p47(phox) and p67(phox) in Hearts of Diabetic Rats. (Sharma NM, Rabeler B, Zheng H, Raichlin E, Patel KP) Oxid Med Cell Longev 2016;2016:5868913       9 Citations
1Hyperglycemia induces embryopathy, even in the absence of systemic maternal diabetes: an in vivo test of the fuel mediated teratogenesis hypothesis. (Baack ML, Wang C, Hu S, Segar JL, Norris AW) Reprod Toxicol 2014 Jul;46:129-36       19 Citations
2Vascular dysfunction in diabetes mellitus: large conductance calcium-activated potassium channels as part of a subsarcolemmal signaling soiree. (Gutterman DD, Durand MJ) Circ Res 2014 Feb 14;114(4):588-90       3 Citations
1Genomic and metabolic disposition of non-obese type 2 diabetic rats to increased myocardial fatty acid metabolism. (Devanathan S, Nemanich ST, Kovacs A, Fettig N, Gropler RJ, Shoghi KI) PLoS One 2013;8(10):e78477       15 Citations
1Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes. (King AJ, Guo Y, Cai D, Hollister-Lock J, Morris B, Salvatori A, Corbett JA, Bonner-Weir S, Shoelson SE, Weir GC) PLoS One 2013;8(10):e77452       7 Citations
1Protective role for netrin-1 during diabetic nephropathy. (Tak E, Ridyard D, Badulak A, Giebler A, Shabeka U, Werner T, Clambey E, Moldovan R, Zimmerman MA, Eltzschig HK, Grenz A) J Mol Med (Berl) 2013 Sep;91(9):1071-80       19 Citations
1Low-intensity far-red light inhibits early lesions that contribute to diabetic retinopathy: in vivo and in vitro. (Tang J, Du Y, Lee CA, Talahalli R, Eells JT, Kern TS) Invest Ophthalmol Vis Sci 2013 May 01;54(5):3681-90       48 Citations
1Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. (Chow JP, Simionescu DT, Warner H, Wang B, Patnaik SS, Liao J, Simionescu A) Biomaterials 2013 Jan;34(3):685-95       24 Citations
1Sex-specific programming of hypertension in offspring of late-gestation diabetic rats. (Katkhuda R, Peterson ES, Roghair RD, Norris AW, Scholz TD, Segar JL) Pediatr Res 2012 Oct;72(4):352-61       30 Citations
1Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36. (Zhu W, Li W, Silverstein RL) Blood 2012 Jun 21;119(25):6136-44       58 Citations
1Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes. (Elmarakby AA, Faulkner J, Al-Shabrawey M, Wang MH, Maddipati KR, Imig JD) Am J Physiol Regul Integr Comp Physiol 2011 Nov;301(5):R1307-17       60 Citations
1Impaired sensory nerve function and axon morphology in mice with diabetic neuropathy. (Lennertz RC, Medler KA, Bain JL, Wright DE, Stucky CL) J Neurophysiol 2011 Aug;106(2):905-14       37 Citations
1Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus. (Zimmerman MA, Haskins K, Bradley B, Gilman J, Gamboni-Robertson F, Flores SC) J Surg Res 2011 Jun 15;168(2):e195-202       2 Citations
1Programming of adult cardiovascular disease following exposure to late-gestation hyperglycemia. (Agoudemos M, Reinking BE, Koppenhafer SL, Segar JL, Scholz TD) Neonatology 2011;100(2):198-205       11 Citations
1Renal sympathetic nervous system hyperactivity in early streptozotocin-induced diabetic kidney disease. (Salman IM, Ameer OZ, Sattar MA, Abdullah NA, Yam MF, Abdullah GZ, Abdulkarim MF, Khan MA, Johns EJ) Neurourol Urodyn 2011 Mar;30(3):438-46       16 Citations
1Protein kinase C upregulates intercellular adhesion molecule-1 and leukocyte-endothelium interactions in hyperglycemia via activation of endothelial expressed calpain. (Smolock AR, Mishra G, Eguchi K, Eguchi S, Scalia R) Arterioscler Thromb Vasc Biol 2011 Feb;31(2):289-96       27 Citations
1Characterization of renal hemodynamic and structural alterations in rat models of renal impairment: role of renal sympathoexcitation. (Salman IM, Ameer OZ, Sattar MA, Abdullah NA, Yam MF, Najim HS, Abdulkarim MF, Abdullah GZ, Kaur G, Khan MA, Johns EJ) J Nephrol 2011 Jan-Feb;24(1):68-77       10 Citations
1Effects of low-level light therapy on streptozotocin-induced diabetic kidney. (Lim J, Sanders RA, Snyder AC, Eells JT, Henshel DS, Watkins JB 3rd) J Photochem Photobiol B 2010 May 03;99(2):105-10       23 Citations
1Enhanced proliferation and migration of vascular smooth muscle cells in response to vascular injury under hyperglycemic conditions is controlled by beta3 integrin signaling. (Panchatcharam M, Miriyala S, Yang F, Leitges M, Chrzanowska-Wodnicka M, Quilliam LA, Anaya P, Morris AJ, Smyth SS) Int J Biochem Cell Biol 2010 Jun;42(6):965-74       37 Citations
2Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats. (Moralejo DH, Hansen CT, Treuting P, Hessner MJ, Fuller JM, Van Yserloo B, Jensen R, Osborne W, Kwitek AE, Lernmark A) Physiol Genomics 2010 Mar 03;41(1):9-20       7 Citations
1Functional subtypes of renal alpha1-adrenoceptor in spontaneously hypertensive rats with streptozotocin-induced experimental diabetic nephropathy. (Khan MA, Sattar MA, Abdullah NA, Abdulla MH, Salman IM, Kazi RN, Swarup KR, Rathore HA, Basri F, Hussain NM, Dewa A, Johns EJ) Kidney Blood Press Res 2009;32(5):349-59       7 Citations
1Cardiomyopathy in offspring of diabetic rats is associated with activation of the MAPK and apoptotic pathways. (Reinking BE, Wedemeyer EW, Weiss RM, Segar JL, Scholz TD) Cardiovasc Diabetol 2009 Jul 31;8:43       28 Citations
1Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene. (Fuller JM, Bogdani M, Tupling TD, Jensen RA, Pefley R, Manavi S, Cort L, Blankenhorn EP, Mordes JP, Lernmark A, Kwitek AE) Physiol Genomics 2009 Jun 10;38(1):89-97       13 Citations
1Programming of growth, insulin resistance and vascular dysfunction in offspring of late gestation diabetic rats. (Segar EM, Norris AW, Yao JR, Hu S, Koppenhafer SL, Roghair RD, Segar JL, Scholz TD) Clin Sci (Lond) 2009 Jul 02;117(3):129-38       32 Citations
1Effects of low-level light therapy on hepatic antioxidant defense in acute and chronic diabetic rats. (Lim J, Ali ZM, Sanders RA, Snyder AC, Eells JT, Henshel DS, Watkins JB 3rd) J Biochem Mol Toxicol 2009 Jan-Feb;23(1):1-8       24 Citations
1Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic Zucker rats. (Tabatabai NM, Sharma M, Blumenthal SS, Petering DH) Diabetes Res Clin Pract 2009 Jan;83(1):e27-30       70 Citations
1Clonidine and a novel clonidine analog AL-12 cause sympathoinhibition in spontaneously hypertensive and diabetic spontaneously hypertensive rats. (Lazahari MI, Sattar MA, Abdullah NA, Khan MA, Johns EJ) Methods Find Exp Clin Pharmacol 2008 Apr;30(3):193-9       1 Citation
1Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. (Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD) Clin Sci (Lond) 2009 Jan;116(1):61-70       62 Citations
1Functional subtypes of renal alpha1-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension. (Armenia A, Sattar MA, Abdullah NA, Khan MA, Johns EJ) Acta Pharmacol Sin 2008 May;29(5):564-72       12 Citations
1Alpha1A- and alpha1D-adrenoceptors are the major functional subtypes of renal alpha1-adrenoceptors in streptozotocin-induced diabetic and normal Sprague-Dawley rats. (Armenia, Sattar MA, Abdullah NA, Khan MA, Johns EJ) Auton Autacoid Pharmacol 2008 Jan;28(1):1-10       11 Citations
2Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection. (Jamnicki-Abegg M, Weihrauch D, Chiari PC, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) J Cardiovasc Pharmacol 2007 Dec;50(6):670-6       14 Citations
1Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. (Isermann B, Vinnikov IA, Madhusudhan T, Herzog S, Kashif M, Blautzik J, Corat MA, Zeier M, Blessing E, Oh J, Gerlitz B, Berg DT, Grinnell BW, Chavakis T, Esmon CT, Weiler H, Bierhaus A, Nawroth PP) Nat Med 2007 Nov;13(11):1349-58       275 Citations
1Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats. (Bubolz AH, Wu Q, Larsen BT, Gutterman DD, Liu Y) Am J Physiol Heart Circ Physiol 2007 Oct;293(4):H2231-7       23 Citations
1Thiol-related genes in diabetic complications: a novel protective role for endogenous thioredoxin 2. (Liang M, Pietrusz JL) Arterioscler Thromb Vasc Biol 2007 Jan;27(1):77-83       42 Citations
1Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats. (El-Alfy AT, Ahmed AA, Fatani AJ) Pharmacol Res 2005 Sep;52(3):264-70       137 Citations
1Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes. (Knoll KE, Pietrusz JL, Liang M) Physiol Genomics 2005 Apr 14;21(2):222-9       46 Citations
2Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. (LaDisa JF Jr, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H601-7       33 Citations
2Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. (Whelan HT, Buchmann EV, Dhokalia A, Kane MP, Whelan NT, Wong-Riley MT, Eells JT, Gould LJ, Hammamieh R, Das R, Jett M) J Clin Laser Med Surg 2003 Apr;21(2):67-74       152 Citations
1The coronary circulation in diabetes: influence of reactive oxygen species on K+ channel-mediated vasodilation. (Liu Y, Gutterman DD) Vascul Pharmacol 2002 Jan;38(1):43-9       82 Citations
1Isoflurane-induced preconditioning is attenuated by diabetes. (Tanaka K, Kehl F, Gu W, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2002 Jun;282(6):H2018-23       86 Citations
1Renal AT1 receptor protein expression during the early stage of diabetes mellitus. (Harrison-Bernard LM, Imig JD, Carmines PK) Int J Exp Diabetes Res 2002 Apr-Jun;3(2):97-108       31 Citations
1Diabetes attenuates the minimum anaesthetic concentration (MAC) and MAC-blocking adrenergic response reducing actions of clonidine in rats. (Kita T, Kagawa K, Mammoto T, Takada K, Hayashi Y, Mashimo T, Kishi Y) Acta Anaesthesiol Scand 2001 Nov;45(10):1230-4       4 Citations
1Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels. (Kersten JR, Montgomery MW, Ghassemi T, Gross ER, Toller WG, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1744-50       112 Citations
1Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat. (Zimpelmann J, Kumar D, Levine DZ, Wehbi G, Imig JD, Navar LG, Burns KD) Kidney Int 2000 Dec;58(6):2320-30       109 Citations
1Impaired dilation of coronary arterioles during increases in myocardial O(2) consumption with hyperglycemia. (Ammar RF Jr, Gutterman DD, Brooks LA, Dellsperger KC) Am J Physiol Endocrinol Metab 2000 Oct;279(4):E868-74       20 Citations
1Free radicals mediate endothelial dysfunction of coronary arterioles in diabetes. (Ammar RF Jr, Gutterman DD, Brooks LA, Dellsperger KC) Cardiovasc Res 2000 Aug 18;47(3):595-601       51 Citations
1Ingested interferon-alpha prevents allograft islet transplant rejection. (Brod SA, Katz S, Phan T, Stepkowski S) Transplantation 2000 May 27;69(10):2162-6       6 Citations
1Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality. (Kersten JR, Toller WG, Gross ER, Pagel PS, Warltier DC) Am J Physiol Heart Circ Physiol 2000 Apr;278(4):H1218-24       187 Citations
1Acetylcholine-induced arteriolar dilation is reduced in streptozotocin-induced diabetic rats with motor nerve dysfunction. (Terata K, Coppey LJ, Davidson EP, Dunlap JA, Gutterman DD, Yorek MA) Br J Pharmacol 1999 Oct;128(3):837-43       49 Citations
1Pancreatic transplantation reverses endothelial dysfunction in experimental diabetes mellitus. (Pieper GM, Adams MB, Roza AM) Surgery 1998 Jan;123(1):89-95       10 Citations
1Chronic treatment with the 21-aminosteroid U74389F, an inhibitor of lipid peroxidation, does not prevent diabetic endothelial dysfunction. (Pieper GM, Jordan M, Roza AM) Cardiovasc Drugs Ther 1997 Jul;11(3):435-40       1 Citation
1Diabetic-induced endothelial dysfunction in rat aorta: role of hydroxyl radicals. (Pieper GM, Langenstroer P, Siebeneich W) Cardiovasc Res 1997 Apr;34(1):145-56       154 Citations
1Chronic treatment in vivo with dimethylthiourea, a hydroxyl radical scavenger, prevents diabetes-induced endothelial dysfunction. (Pieper GM, Siebeneich W, Roza AM, Jordan M, Adams MB) J Cardiovasc Pharmacol 1996 Dec;28(6):741-5       49 Citations
1Syngeneic pancreatic islet transplantation reverses endothelial dysfunction in experimental diabetes. (Pieper GM, Jordan M, Adams MB, Roza AM) Diabetes 1995 Sep;44(9):1106-13       42 Citations
1Peroxidative stress in diabetic blood vessels. Reversal by pancreatic islet transplantation. (Pieper GM, Jordan M, Dondlinger LA, Adams MB, Roza AM) Diabetes 1995 Aug;44(8):884-9       103 Citations
1Normalization of pancreatic exocrine enzymes by islet transplantation in diabetic rats. (Lee PC, Jordan M, Pieper GM, Roza AM) Biochem Cell Biol 1995 May-Jun;73(5-6):269-73       5 Citations
1Ramipril prevents hypersensitivity to phenylephrine in aorta from streptozotocin-induced diabetic rats. (Murray P, Pitt B, Webb RC) Diabetologia 1994 Jul;37(7):664-70       18 Citations
2Free radicals in pancreatic and cardiac allograft rejection. (Roza AM, Pieper G, Moore-Hilton G, Johnson CP, Adams MB) Transplant Proc 1994 Apr;26(2):544-5       11 Citations
1Potential autoantigens in IDDM. Expression of carboxypeptidase-H and insulin but not glutamate decarboxylase on the beta-cell surface. (Aguilar-Diosdado M, Parkinson D, Corbett JA, Kwon G, Marshall CA, Gingerich RL, Santiago JV, McDaniel ML) Diabetes 1994 Mar;43(3):418-25       27 Citations
1Accelerated gastric emptying in diabetic rodents: effect of insulin treatment and pancreas transplantation. (Nowak TV, Roza AM, Weisbruch JP, Brosnan MR) J Lab Clin Med 1994 Jan;123(1):110-6       38 Citations
1Characterization of NADPH diaphorase activity in rat sympathetic autonomic ganglia--effect of diabetes and aging. (Schmidt RE, Dorsey DA, McDaniel ML, Corbett JA) Brain Res 1993 Jul 23;617(2):343-8       19 Citations
1Hydroxyl radicals mediate injury to endothelium-dependent relaxation in diabetic rat. (Pieper GM, Langenstroer P, Gross GJ) Mol Cell Biochem 1993 May 26;122(2):139-45       41 Citations
1Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation. (Tilton RG, Chang K, Hasan KS, Smith SR, Petrash JM, Misko TP, Moore WM, Currie MG, Corbett JA, McDaniel ML) Diabetes 1993 Feb;42(2):221-32       299 Citations
1PGE2 prevents anomalies induced by hyperglycemia or diabetic serum in mouse embryos. (Goto MP, Goldman AS, Uhing MR) Diabetes 1992 Dec;41(12):1644-50       49 Citations
1Bioassay of endothelium-derived relaxing factor in diabetic rat aorta. (Pieper GM, Mei DA, Langenstroer P, O'Rourke ST) Am J Physiol 1992 Sep;263(3 Pt 2):H676-80       82 Citations
1Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. (Langenstroer P, Pieper GM) Am J Physiol 1992 Jul;263(1 Pt 2):H257-65       163 Citations
2Untreated diabetes mellitus promotes intestinal microbial overgrowth. (Roza AM, Edmiston CE Jr, Frantzides C, Moore GH, Nowak TV, Johnson CP, Adams MB) Am J Surg 1992 Apr;163(4):417-21       14 Citations
2Elimination of OX8+ cells prolongs cardiac but not pancreatic allograft survival across minor (non-MHC) histocompatibility barriers. (Roza AM, Johnson CP, Adams MB, Naji A) Transplant Proc 1990 Apr;22(2):747-8       1 Citation
1Fluidity of rat liver Golgi membranes in streptozotocin diabetes. A spin label study. (Kordowiak AM, Wojas J, Subczynski WK) Biochim Biophys Acta 1990 Mar;1022(3):296-302       7 Citations
1Glomerular eicosanoids and diabetes mellitus. (Dunn MJ) J Lab Clin Med 1989 Jun;113(6):659-61       5 Citations
2Effect of elimination of OX-19+ and OX-8+ T-cell subsets upon pancreatic allograft survival. (Roza AM, Markmann JF, Kimura H, Johnson CP, Adams MB, Naji A) J Surg Res 1989 Apr;46(4):395-9       1 Citation
1Triglyceride-lowering effect of dietary vitamin E in streptozocin-induced diabetic rats. Increased lipoprotein lipase activity in livers of diabetic rats fed high dietary vitamin E. (Pritchard KA Jr, Patel ST, Karpen CW, Newman HA, Panganamala RV) Diabetes 1986 Mar;35(3):278-81    
1Improvement of myocardial function in diabetic rats after treatment with L-carnitine. (Paulson DJ, Schmidt MJ, Traxler JS, Ramacci MT, Shug AL) Metabolism 1984 Apr;33(4):358-63       59 Citations
1Alterations of the prostacyclin-thromboxane ratio in streptozotocin induced diabetic rats. (Karpen CW, Pritchard KA Jr, Merola AJ, Panganamala RV) Prostaglandins Leukot Med 1982 Feb;8(2):93-103       63 Citations
1Effect of altered availability of energy-yielding substrates upon survival from hypoxia in mice. (Kirsch JR, D'Alecy LG) Stroke 1979 May-Jun;10(3):288-91       37 Citations
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a