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Publications indexed to the term T-Lymphocytes, Cytotoxic

1Manufacture and Characterization of Good Manufacturing Practice-Compliant SARS-COV-2 Cytotoxic T Lymphocytes. (Chu Y, Milner J, Lamb M, Maryamchik E, Rigot O, Ayello J, Harrison L, Shaw R, Behbehani GK, Mardis ER, Miller K, Prakruthi Rao Venkata L, Chang H, Lee D, Rosenthal E, Kadauke S, Bunin N, Talano JA, Johnson B, Wang Y, Cairo MS) J Infect Dis 2023 Mar 28;227(6):788-799    
1Isolation of Innate Lymphoid Cells from Murine Intestinal Lamina Propria. (Mei A, Hashemi E, Khalil M, Wang D, Malarkannan S) Methods Mol Biol 2022;2463:3-9       1 Citation
1T cell receptor-targeted immunotherapeutics drive selective in vivo HIV- and CMV-specific T cell expansion in humanized mice. (Li M, Garforth SJ, O'Connor KE, Su H, Lee DM, Celikgil A, Chaparro RJ, Seidel RD, Jones RB, Arav-Boger R, Almo SC, Goldstein H) J Clin Invest 2021 Dec 01;131(23)       4 Citations
3Self-Renewing Islet TCF1+ CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1- Terminal Effectors during the Progression of Type 1 Diabetes. (Ciecko AE, Schauder DM, Foda B, Petrova G, Kasmani MY, Burns R, Lin CW, Drobyski WR, Cui W, Chen YG) J Immunol 2021 Oct 15;207(8):1990-2004       8 Citations
1The Role of microRNAs in NK Cell Development and Function. (Nanbakhsh A, Malarkannan S) Cells 2021 Aug 07;10(8)       8 Citations
3Acute SARS-CoV-2 pneumonitis with cytotoxic CD8 positive T-lymphocytes: Case report and review of the literature. (Puzyrenko A, Felix JC, Sun Y, Rui H, Sheinin Y) Pathol Res Pract 2021 Apr;220:153380       5 Citations
4Mirc11 Disrupts Inflammatory but Not Cytotoxic Responses of NK Cells. (Nanbakhsh A, Srinivasamani A, Holzhauer S, Riese MJ, Zheng Y, Wang D, Burns R, Reimer MH, Rao S, Lemke A, Tsaih SW, Flister MJ, Lao S, Dahl R, Thakar MS, Malarkannan S) Cancer Immunol Res 2019 Oct;7(10):1647-1662       10 Citations
3STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models. (Jing W, McAllister D, Vonderhaar EP, Palen K, Riese MJ, Gershan J, Johnson BD, Dwinell MB) J Immunother Cancer 2019 Apr 29;7(1):115       89 Citations
1Closed-system manufacturing of CD19 and dual-targeted CD20/19 chimeric antigen receptor T cells using the CliniMACS Prodigy device at an academic medical center. (Zhu F, Shah N, Xu H, Schneider D, Orentas R, Dropulic B, Hari P, Keever-Taylor CA) Cytotherapy 2018 Mar;20(3):394-406       63 Citations
1The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy. (McKenzie JA, Mbofung RM, Malu S, Zhang M, Ashkin E, Devi S, Williams L, Tieu T, Peng W, Pradeep S, Xu C, Zorro Manrique S, Liu C, Huang L, Chen Y, Forget MA, Haymaker C, Bernatchez C, Satani N, Muller F, Roszik J, Kalra A, Heffernan T, Sood A, Hu J, Amaria R, Davis RE, Hwu P) J Natl Cancer Inst 2018 Jul 01;110(7):777-786       54 Citations
1Formulation of the bivalent prostate cancer vaccine with surgifoam elicits antigen-specific effector T cells in PSA-transgenic mice. (Karan D) Vaccine 2017 Oct 13;35(43):5794-5798       7 Citations
1Murine splenic CD4⁺ T cells, induced by innate immune cell interactions and secreted factors, develop antileukemia cytotoxicity. (Nelles ME, Moreau JM, Furlonger CL, Berger A, Medin JA, Paige CJ) Cancer Immunol Res 2014 Nov;2(11):1113-24       9 Citations
1Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing. (Gameiro SR, Jammeh ML, Wattenberg MM, Tsang KY, Ferrone S, Hodge JW) Oncotarget 2014 Jan 30;5(2):403-16       311 Citations
1Editorial: Optimizing iTreg differentiation: STATs in the balance. (Williams CB, Chatila TA) J Leukoc Biol 2014 Feb;95(2):197-8       1 Citation
1STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity. (Betts BC, Veerapathran A, Pidala J, Yu XZ, Anasetti C) J Leukoc Biol 2014 Feb;95(2):205-13       27 Citations
1Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. (Ip CW, Kroner A, Groh J, Huber M, Klein D, Spahn I, Diem R, Williams SK, Nave KA, Edgar JM, Martini R) PLoS One 2012;7(8):e42554       24 Citations
1Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse. (Bobbala D, Chen XL, Leblanc C, Mayhue M, Stankova J, Tanaka T, Chen YG, Ilangumaran S, Ramanathan S) Diabetologia 2012 Nov;55(11):3010-20       33 Citations
1Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients. (Clark RA, Watanabe R, Teague JE, Schlapbach C, Tawa MC, Adams N, Dorosario AA, Chaney KS, Cutler CS, Leboeuf NR, Carter JB, Fisher DC, Kupper TS) Sci Transl Med 2012 Jan 18;4(117):117ra7       286 Citations
1Dual antigen target-based immunotherapy for prostate cancer eliminates the growth of established tumors in mice. (Karan D, Dubey S, Van Veldhuizen P, Holzbeierlein JM, Tawfik O, Thrasher JB) Immunotherapy 2011 Jun;3(6):735-46       20 Citations
1Anti-leukemia activity of in vitro-expanded human gamma delta T cells in a xenogeneic Ph+ leukemia model. (Siegers GM, Felizardo TC, Mathieson AM, Kosaka Y, Wang XH, Medin JA, Keating A) PLoS One 2011 Feb 03;6(2):e16700       34 Citations
2Expression of natural killer receptors in T- and NK-cells: comparison of healthy individuals, patients with prior stem cell transplant, and patients undergoing chemotherapy. (Olteanu H, Schur BC, Bredeson C, Atallah E, Kroft SH) Leuk Lymphoma 2010 Mar;51(3):481-7       5 Citations
1Generation of cytotoxic T-cell lines using overlapping pentadecapeptides derived from conserved regions of the adenovirus hexon protein. (Zhu F, Xu H, Tsao A, Margolis DA, Keever-Taylor CA) J Gen Virol 2010 Jun;91(Pt 6):1577-89       5 Citations
1CpG oligonucleotide as an adjuvant for the treatment of prostate cancer. (Lubaroff DM, Karan D) Adv Drug Deliv Rev 2009 Mar 28;61(3):268-74       20 Citations
1Stimulation by means of dendritic cells followed by Epstein-Barr virus-transformed B cells as antigen-presenting cells is more efficient than dendritic cells alone in inducing Aspergillus f16-specific cytotoxic T cell responses. (Zhu F, Ramadan G, Davies B, Margolis DA, Keever-Taylor CA) Clin Exp Immunol 2008 Feb;151(2):284-96       21 Citations
1Quantitative measurement of pathogen-specific human memory T cell repertoire diversity using a CDR3 beta-specific microarray. (Wang X, Jia S, Meyer L, Yassai MB, Naumov YN, Gorski J, Hessner MJ) BMC Genomics 2007 Sep 19;8:329       4 Citations
1Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine. (Karan D, Krieg AM, Lubaroff DM) Int J Cancer 2007 Oct 01;121(7):1520-8       41 Citations
1Frequency analysis of HLA-B7-restricted Epstein-Barr virus-specific cytotoxic T lymphocytes in patients with multiple sclerosis and healthy controls. (Gronen F, Ruprecht K, Weissbrich B, Klinker E, Kroner A, Hofstetter HH, Rieckmann P) J Neuroimmunol 2006 Nov;180(1-2):185-92       40 Citations
1Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer. (Lubaroff DM, Karan D, Andrews MP, Acosta A, Abouassaly C, Sharma M, Krieg AM) Vaccine 2006 Aug 28;24(35-36):6155-62       29 Citations
1Hemophagocytic lymphohistiocytosis: diagnosis, pathophysiology, treatment, and future perspectives. (Verbsky JW, Grossman WJ) Ann Med 2006;38(1):20-31       174 Citations
1Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. (Grossman WJ, Verbsky JW, Tollefsen BL, Kemper C, Atkinson JP, Ley TJ) Blood 2004 Nov 01;104(9):2840-8       400 Citations
1Suppression of EBV release from irradiated B lymphoblastoid cell-lines: superior activity of ganciclovir compared with acyclovir. (Keever-Taylor CA, Behn B, Konings S, Orentas R, Davies B, Margolis D) Cytotherapy 2003;5(4):323-35       14 Citations
1Protection induced by intramuscular immunization with DNA vaccines of pseudorabies in mice, rabbits and piglets. (Hong W, Xiao S, Zhou R, Fang L, He Q, Wu B, Zhou F, Chen H) Vaccine 2002 Jan 15;20(7-8):1205-14       43 Citations
1Cytomegalovirus-specific cytolytic T-cell lines and clones generated against adenovirus-pp65-infected dendritic cells. (Keever-Taylor CA, Margolis D, Konings S, Sandford GR, Nicolette CA, Lawendowski C, Burns WH) Biol Blood Marrow Transplant 2001;7(5):247-56       30 Citations
1Polyoma virus infection after renal transplantation. Use of immunostaining as a guide to diagnosis. (Ahuja M, Cohen EP, Dayer AM, Kampalath B, Chang CC, Bresnahan BA, Hariharan S) Transplantation 2001 Apr 15;71(7):896-9       120 Citations
1Host determinants in HIV infection and disease. Part 1: cellular and humoral immune responses. (Hogan CM, Hammer SM) Ann Intern Med 2001 May 01;134(9 Pt 1):761-76       104 Citations
1Anti-CD3 epsilon F(ab')2 prevents graft-versus-host disease by selectively depleting donor T cells activated by recipient alloantigens. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2001 May 01;166(9):5835-9       32 Citations
1Protection from lethal murine graft-versus-host disease without compromise of alloengraftment using transgenic donor T cells expressing a thymidine kinase suicide gene. (Drobyski WR, Morse HC 3rd, Burns WH, Casper JT, Sandford G) Blood 2001 Apr 15;97(8):2506-13       26 Citations
1Ex vivo generation of cytotoxic T lymphocytes specific for one or two distinct viruses for the prophylaxis of patients receiving an allogeneic bone marrow transplant. (Regn S, Raffegerst S, Chen X, Schendel D, Kolb HJ, Roskrow M) Bone Marrow Transplant 2001 Jan;27(1):53-64       46 Citations
1Interferon alpha in combination with GM-CSF induces the differentiation of leukaemic antigen-presenting cells that have the capacity to stimulate a specific anti-leukaemic cytotoxic T-cell response from patients with chronic myeloid leukaemia. (Chen X, Regn S, Raffegerst S, Kolb HJ, Roskrow M) Br J Haematol 2000 Nov;111(2):596-607       56 Citations
1Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens. (Malarkannan S, Horng T, Eden P, Gonzalez F, Shih P, Brouwenstijn N, Klinge H, Christianson G, Roopenian D, Shastri N) Immunity 2000 Sep;13(3):333-44       76 Citations
1TGF-beta 2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis. (Drescher KM, Murray PD, Lin X, Carlino JA, Rodriguez M) J Immunol 2000 Mar 15;164(6):3207-13       33 Citations
1Role of immunoregulatory donor T cells in suppression of graft-versus-host disease following donor leukocyte infusion therapy. (Johnson BD, Becker EE, LaBelle JL, Truitt RL) J Immunol 1999 Dec 15;163(12):6479-87       62 Citations
1Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplantation. (Truitt RL, Johnson BD, Hanke C, Talib S, Hearst JE) J Immunol 1999 Nov 01;163(9):5145-56       47 Citations
1Absence of spontaneous central nervous system remyelination in class II-deficient mice infected with Theiler's virus. (Njenga MK, Murray PD, McGavern D, Lin X, Drescher KM, Rodriguez M) J Neuropathol Exp Neurol 1999 Jan;58(1):78-91       30 Citations
1Selective induction of protective MHC class I-restricted CTL in the intestinal lamina propria of rhesus monkeys by transient SIV infection of the colonic mucosa. (Murphey-Corb M, Wilson LA, Trichel AM, Roberts DE, Xu K, Ohkawa S, Woodson B, Bohm R, Blanchard J) J Immunol 1999 Jan 01;162(1):540-9       88 Citations
1Role of CD28 in acute graft-versus-host disease. (Yu XZ, Martin PJ, Anasetti C) Blood 1998 Oct 15;92(8):2963-70       57 Citations
1Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. (Albert ML, Pearce SF, Francisco LM, Sauter B, Roy P, Silverstein RL, Bhardwaj N) J Exp Med 1998 Oct 05;188(7):1359-68       1069 Citations
1The molecular and functional characterization of a dominant minor H antigen, H60. (Malarkannan S, Shih PP, Eden PA, Horng T, Zuberi AR, Christianson G, Roopenian D, Shastri N) J Immunol 1998 Oct 01;161(7):3501-9       212 Citations
1Perforin-dependent neurologic injury in a viral model of multiple sclerosis. (Murray PD, McGavern DB, Lin X, Njenga MK, Leibowitz J, Pease LR, Rodriguez M) J Neurosci 1998 Sep 15;18(18):7306-14       98 Citations
1Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity. (Lin X, Pease LR, Murray PD, Rodriguez M) J Immunol 1998 Jun 01;160(11):5661-8       32 Citations
1IL-2 induces Fas ligand/Fas (CD95L/CD95) cytotoxicity in CD8+ and CD4+ T lymphocyte clones. (Esser MT, Dinglasan RD, Krishnamurthy B, Gullo CA, Graham MB, Braciale VL) J Immunol 1997 Jun 15;158(12):5612-8       51 Citations
1Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. (Pewe L, Wu GF, Barnett EM, Castro RF, Perlman S) Immunity 1996 Sep;5(3):253-62       83 Citations
1Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts. (Drobyski WR, Majewski D) Blood 1996 Jun 15;87(12):5355-69       11 Citations
1Interferon-beta 1b treatment decreases tumor necrosis factor-alpha and increases interleukin-6 production in multiple sclerosis. (Brod SA, Marshall GD Jr, Henninger EM, Sriram S, Khan M, Wolinsky JS) Neurology 1996 Jun;46(6):1633-8       125 Citations
1Delayed infusion of immunocompetent donor cells after bone marrow transplantation breaks graft-host tolerance allows for persistent antileukemic reactivity without severe graft-versus-host disease. (Johnson BD, Truitt RL) Blood 1995 Jun 01;85(11):3302-12       134 Citations
1Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. (Graham MB, Dalton DK, Giltinan D, Braciale VL, Stewart TA, Braciale TJ) J Exp Med 1993 Nov 01;178(5):1725-32       221 Citations