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Shyam S. Chaurasia PhD

Shyam S. Chaurasia PhD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Ophthalmology and Visual Sciences
Program: Research

Member of the Cancer Center


Research Experience

  • Adenylyl Cyclases
  • Bone Morphogenetic Protein 7
  • Calcium-Binding Proteins
  • Circadian Rhythm
  • Corneal Dystrophies, Hereditary
  • Corneal Opacity
  • Cryptochromes
  • Diabetic Retinopathy
  • Disease Models, Animal
  • Dopamine
  • Dry Eye Syndromes
  • Extracellular Matrix Proteins
  • Eye
  • Fibroblasts
  • Fibrosis
  • Inflammation
  • Inhibitor of Differentiation Proteins
  • Interleukin 1 Receptor Antagonist Protein
  • Interleukin-1beta
  • Keratoconus
  • Macular Edema
  • Matrix Metalloproteinase 9
  • Meibomian Glands
  • Melatonin
  • Monocytes
  • Myofibroblasts
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • Neovascularization, Pathologic
  • Ophthalmology
  • Photoreceptor Cells
  • Photoreceptor Cells, Vertebrate
  • Photorefractive Keratectomy
  • Pineal Gland
  • Pterygium
  • Retina
  • Retinal Degeneration
  • Transforming Growth Factor beta
  • Triiodothyronine
  • Vascular Endothelial Growth Factor A
  • Wound Healing
  • Publications (96)

  • Glutathione is a potential therapeutic target for acrolein toxicity in the cornea. (Gupta S, Kamil S, Sinha PR, Rodier JT, Chaurasia SS, Mohan RR) Toxicol Lett 2021 Apr 01;340:33-42 PMID: 33421550 01/10/2021    
  • A Novel Topical Ophthalmic Formulation to Mitigate Acute Mustard Gas Keratopathy In Vivo: A Pilot Study. (Tripathi R, Balne PK, Sinha NR, Martin LM, Kamil S, Landreneau JR, Gupta S, Rodier JT, Sinha PR, Hesemann NP, Hofmann AC, Fink MK, Chaurasia SS, Mohan RR) Transl Vis Sci Technol 2020 11;9(12):6 PMID: 33200047 PMCID: PMC7645241 11/18/2020    
  • A rabbit model for evaluating ocular damage from acrolein toxicity in vivo. (Gupta S, Fink MK, Martin LM, Sinha PR, Rodier JT, Sinha NR, Hesemann NP, Chaurasia SS, Mohan RR) Ann N Y Acad Sci 2020 11;1480(1):233-245 PMID: 33067838 10/18/2020       1 Citation
  • MicroRNA-15b Targets VEGF and Inhibits Angiogenesis in Proliferative Diabetic Retinopathy. (Yang Y, Liu Y, Li Y, Chen Z, Xiong Y, Zhou T, Tao W, Xu F, Yang H, Ylä-Herttuala S, Chaurasia SS, Adam WC, Yang K) J Clin Endocrinol Metab 2020 11 01;105(11) PMID: 32797181 08/17/2020       1 Citation
  • NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy. (Lim RR, Wieser ME, Ganga RR, Barathi VA, Lakshminarayanan R, Mohan RR, Hainsworth DP, Chaurasia SS) Int J Mol Sci 2020 Jan 30;21(3) PMID: 32019187 PMCID: PMC7037099 02/06/2020       7 Citations
  • Correlation between systemic S100A8 and S100A9 levels and severity of diabetic retinopathy in patients with type 2 diabetes mellitus. (Lim RR, Vaidya T, Gadde SG, Yadav NK, Sethu S, Hainsworth DP, Mohan RR, Ghosh A, Chaurasia SS) Diabetes Metab Syndr 2019 Mar - Apr;13(2):1581-1589 PMID: 31336525 07/25/2019       7 Citations
  • Is sex a biological variable in corneal wound healing? (Tripathi R, Giuliano EA, Gafen HB, Gupta S, Martin LM, Sinha PR, Rodier JT, Fink MK, Hesemann NP, Chaurasia SS, Mohan RR) Exp Eye Res 2019 10;187:107705 PMID: 31226339 06/22/2019       4 Citations
  • Characterization of a functionally active primary microglial cell culture from the pig retina. (Lim RR, Hainsworth DP, Mohan RR, Chaurasia SS) Exp Eye Res 2019 08;185:107670 PMID: 31103710 05/20/2019       4 Citations
  • Decorin antagonizes corneal fibroblast migration via caveolae-mediated endocytosis of epidermal growth factor receptor. (Mohan RR, Tripathi R, Sharma A, Sinha PR, Giuliano EA, Hesemann NP, Chaurasia SS) Exp Eye Res 2019 03;180:200-207 PMID: 30611736 01/07/2019       8 Citations
  • Young Ossabaw Pigs Fed a Western Diet Exhibit Early Signs of Diabetic Retinopathy. (Lim RR, Grant DG, Olver TD, Padilla J, Czajkowski AM, Schnurbusch TR, Mohan RR, Hainsworth DP, Walters EM, Chaurasia SS) Invest Ophthalmol Vis Sci 2018 05 01;59(6):2325-2338 PMID: 29847637 PMCID: PMC5937800 05/31/2018       6 Citations
  • Novel Combination BMP7 and HGF Gene Therapy Instigates Selective Myofibroblast Apoptosis and Reduces Corneal Haze In Vivo. (Gupta S, Fink MK, Ghosh A, Tripathi R, Sinha PR, Sharma A, Hesemann NP, Chaurasia SS, Giuliano EA, Mohan RR) Invest Ophthalmol Vis Sci 2018 02 01;59(2):1045-1057 PMID: 29490341 PMCID: PMC5822743 03/01/2018       23 Citations
  • The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy. (Chaurasia SS, Lim RR, Parikh BH, Wey YS, Tun BB, Wong TY, Luu CD, Agrawal R, Ghosh A, Mortellaro A, Rackoczy E, Mohan RR, Barathi VA) Sci Rep 2018 02 12;8(1):2847 PMID: 29434227 PMCID: PMC5809448 02/13/2018       38 Citations
  • Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients. (Anandalakshmi V, Murugan E, Leng EGT, Ting LW, Chaurasia SS, Yamazaki T, Nagashima T, George BL, Peh GSL, Pervushin K, Lakshminarayanan R, Mehta JS) Biochem J 2017 05 09;474(10):1705-1725 PMID: 28381645 PMCID: PMC5632800 04/07/2017       9 Citations
  • Conventional Versus Inverted Side-cut Flaps for Femtosecond Laser-Assisted LASIK: Laboratory and Clinical Evaluation. (Jhanji V, Chan TC, Li WY, Lim RR, Yu MC, Law K, Yi P, Yip YW, Wang Y, Ng TK, Chaurasia SS, Mohan RR) J Refract Surg 2017 Feb 01;33(2):96-103 PMID: 28192588 02/14/2017       4 Citations
  • Differential Molecular Expression of Extracellular Matrix and Inflammatory Genes at the Corneal Cone Apex Drives Focal Weakening in Keratoconus. (Pahuja N, Kumar NR, Shroff R, Shetty R, Nuijts RM, Ghosh A, Sinha-Roy A, Chaurasia SS, Mohan RR, Ghosh A) Invest Ophthalmol Vis Sci 2016 Oct 01;57(13):5372-5382 PMID: 27732724 10/13/2016       34 Citations
  • Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina. (Su X, Tan QS, Parikh BH, Tan A, Mehta MN, Sia Wey Y, Tun SB, Li LJ, Han XY, Wong TY, Hunziker W, Luu CD, Owada Y, Barathi VA, Zhang SS, Chaurasia SS) Invest Ophthalmol Vis Sci 2016 06 01;57(7):3397-408 PMID: 27367508 07/02/2016       7 Citations
  • Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria. (Lakshminarayanan R, Tan WX, Aung TT, Goh ET, Muruganantham N, Li J, Chang JY, Dikshit N, Saraswathi P, Lim RR, Kang TS, Balamuralidhar V, Sukumaran B, Verma CS, Sivaraman J, Chaurasia SS, Liu S, Beuerman RW) Sci Rep 2016 05 13;6:25905 PMID: 27174567 PMCID: PMC4865820 05/14/2016       13 Citations
  • Author Response: Causal Management of Keratoconus: Controlling Inflammation. (Ghosh A, Shetty R, Chaurasia SS) Invest Ophthalmol Vis Sci 2016 Apr 01;57(4):2165 PMID: 27111564 04/26/2016       1 Citation
  • Insight into membrane selectivity of linear and branched polyethylenimines and their potential as biocides for advanced wound dressings. (Fox SJ, Fazil MH, Dhand C, Venkatesh M, Goh ET, Harini S, Eugene C, Lim RR, Ramakrishna S, Chaurasia SS, Beuerman RW, Verma CS, Verma NK, Loh XJ, Lakshminarayanan R) Acta Biomater 2016 06;37:155-64 PMID: 27079762 04/16/2016       25 Citations
  • pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants. (Murugan E, Venkatraman A, Lei Z, Mouvet V, Rui Yi Lim R, Muruganantham N, Goh E, Swee Lim Peh G, Beuerman RW, Chaurasia SS, Rajamani L, Mehta JS) Sci Rep 2016 Mar 31;6:23836 PMID: 27030015 PMCID: PMC4814907 04/01/2016       6 Citations
  • ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis. (Lim RR, Tan A, Liu YC, Barathi VA, Mohan RR, Mehta JS, Chaurasia SS) Sci Rep 2016 Feb 11;6:20841 PMID: 26865052 PMCID: PMC4750002 02/13/2016       20 Citations
  • Characterization of Inhibitor of differentiation (Id) proteins in human cornea. (Mohan RR, Morgan BR, Anumanthan G, Sharma A, Chaurasia SS, Rieger FG) Exp Eye Res 2016 05;146:145-53 PMID: 26712606 PMCID: PMC4893967 12/30/2015       6 Citations
  • Nanomedicine approaches for corneal diseases. (Chaurasia SS, Lim RR, Lakshminarayanan R, Mohan RR) J Funct Biomater 2015 Apr 30;6(2):277-98 PMID: 25941990 PMCID: PMC4493512 05/06/2015    
  • Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine A. (Shetty R, Ghosh A, Lim RR, Subramani M, Mihir K, Reshma AR, Ranganath A, Nagaraj S, Nuijts RM, Beuerman R, Shetty R, Das D, Chaurasia SS, Sinha-Roy A, Ghosh A) Invest Ophthalmol Vis Sci 2015 Feb 03;56(2):738-50 PMID: 25648341 02/05/2015       72 Citations
  • Biochemical properties and aggregation propensity of transforming growth factor-induced protein (TGFBIp) and the amyloid forming mutants. (Lakshminarayanan R, Chaurasia SS, Murugan E, Venkatraman A, Chai SM, Vithana EN, Beuerman RW, Mehta JS) Ocul Surf 2015 Jan;13(1):9-25 PMID: 25557343 01/06/2015       9 Citations
  • Clinical and genetic aspects of the TGFBI-associated corneal dystrophies. (Lakshminarayanan R, Chaurasia SS, Anandalakshmi V, Chai SM, Murugan E, Vithana EN, Beuerman RW, Mehta JS) Ocul Surf 2014 Oct;12(4):234-51 PMID: 25284770 10/07/2014       44 Citations
  • Involvement of GABA transporters in atropine-treated myopic retina as revealed by iTRAQ quantitative proteomics. (Barathi VA, Chaurasia SS, Poidinger M, Koh SK, Tian D, Ho C, Iuvone PM, Beuerman RW, Zhou L) J Proteome Res 2014 Nov 07;13(11):4647-58 PMID: 25211393 PMCID: PMC4227558 09/12/2014       26 Citations
  • Nanoscale helium ion microscopic analysis of collagen fibrillar changes following femtosecond laser dissection of human cornea. (Riau AK, Poh R, Pickard DS, Park CH, Chaurasia SS, Mehta JS) J Biomed Nanotechnol 2014 Aug;10(8):1552-62 PMID: 25016655 07/16/2014       11 Citations
  • Early corneal nerve damage and recovery following small incision lenticule extraction (SMILE) and laser in situ keratomileusis (LASIK). (Mohamed-Noriega K, Riau AK, Lwin NC, Chaurasia SS, Tan DT, Mehta JS) Invest Ophthalmol Vis Sci 2014 Mar 25;55(3):1823-34 PMID: 24569584 02/27/2014       83 Citations
  • S100A proteins as molecular targets in the ocular surface inflammatory diseases. (Tong L, Lan W, Lim RR, Chaurasia SS) Ocul Surf 2014 Jan;12(1):23-31 PMID: 24439044 01/21/2014       32 Citations
  • LASIK following small incision lenticule extraction (SMILE) lenticule re-implantation: a feasibility study of a novel method for treatment of presbyopia. (Lim CH, Riau AK, Lwin NC, Chaurasia SS, Tan DT, Mehta JS) PLoS One 2013;8(12):e83046 PMID: 24349429 PMCID: PMC3859649 12/19/2013       27 Citations
  • Hevin plays a pivotal role in corneal wound healing. (Chaurasia SS, Perera PR, Poh R, Lim RR, Wong TT, Mehta JS) PLoS One 2013;8(11):e81544 PMID: 24303054 PMCID: PMC3841198 12/05/2013       9 Citations
  • Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells. (Hwang CK, Chaurasia SS, Jackson CR, Chan GC, Storm DR, Iuvone PM) J Neurosci 2013 Sep 18;33(38):14989-97 PMID: 24048828 PMCID: PMC3776053 09/21/2013       34 Citations
  • Mice with a targeted disruption of Slc4a11 model the progressive corneal changes of congenital hereditary endothelial dystrophy. (Han SB, Ang HP, Poh R, Chaurasia SS, Peh G, Liu J, Tan DT, Vithana EN, Mehta JS) Invest Ophthalmol Vis Sci 2013 Sep 27;54(9):6179-89 PMID: 23942972 08/15/2013       29 Citations
  • Reversible femtosecond laser-assisted myopia correction: a non-human primate study of lenticule re-implantation after refractive lenticule extraction. (Riau AK, Angunawela RI, Chaurasia SS, Lee WS, Tan DT, Mehta JS) PLoS One 2013;8(6):e67058 PMID: 23826194 PMCID: PMC3691223 07/05/2013       42 Citations
  • A mouse model of corneal endothelial decompensation using cryoinjury. (Han SB, Ang H, Balehosur D, Peh G, Chaurasia SS, Tan DT, Mehta JS) Mol Vis 2013;19:1222-30 PMID: 23761724 PMCID: PMC3675054 06/14/2013       17 Citations
  • Comparison of four different VisuMax circle patterns for flap creation after small incision lenticule extraction. (Riau AK, Ang HP, Lwin NC, Chaurasia SS, Tan DT, Mehta JS) J Refract Surg 2013 Apr;29(4):236-44 PMID: 23557221 04/06/2013       46 Citations
  • Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. (Tong L, Png E, Aihua H, Yong SS, Yeo HL, Riau A, Mendoz E, Chaurasia SS, Lim CT, Yiu TW, Iismaa SE) Biochim Biophys Acta 2013 Jun;1833(6):1304-15 PMID: 23466867 03/08/2013       11 Citations
  • Reproducibility and age-related changes of ocular parametric measurements in rabbits. (Riau AK, Tan NY, Angunawela RI, Htoon HM, Chaurasia SS, Mehta JS) BMC Vet Res 2012 Aug 19;8:138 PMID: 22901963 PMCID: PMC3514359 08/21/2012       16 Citations
  • Effect of different femtosecond laser-firing patterns on collagen disruption during refractive lenticule extraction. (Riau AK, Angunawela RI, Chaurasia SS, Tan DT, Mehta JS) J Cataract Refract Surg 2012 Aug;38(8):1467-75 PMID: 22814054 07/21/2012       25 Citations
  • Refractive lenticule re-implantation after myopic ReLEx: a feasibility study of stromal restoration after refractive surgery in a rabbit model. (Angunawela RI, Riau AK, Chaurasia SS, Tan DT, Mehta JS) Invest Ophthalmol Vis Sci 2012 Jul 26;53(8):4975-85 PMID: 22743323 06/30/2012       60 Citations
  • Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals. (Robinson R, Barathi VA, Chaurasia SS, Wong TY, Kern TS) Dis Model Mech 2012 Jul;5(4):444-56 PMID: 22730475 PMCID: PMC3380708 06/26/2012       166 Citations
  • Effect of fibrin glue on the biomechanical properties of human Descemet's membrane. (Chaurasia SS, Champakalakshmi R, Li A, Poh R, Tan XW, Lakshminarayanan R, Lim CT, Tan DT, Mehta JS) PLoS One 2012;7(5):e37456 PMID: 22662156 PMCID: PMC3360777 06/05/2012       11 Citations
  • Expression, purification and characterization of fourth FAS1 domain of TGFβIp-associated corneal dystrophic mutants. (Elavazhagan M, Lakshminarayanan R, Zhou L, Ting LW, Tong L, Beuerman RW, Chaurasia SS, Mehta JS) Protein Expr Purif 2012 Jul;84(1):108-15 PMID: 22575305 05/12/2012       12 Citations
  • Manual suction versus femtosecond laser trephination for penetrating keratoplasty: intraocular pressure, endothelial cell damage, incision geometry, and wound healing responses. (Angunawela RI, Riau A, Chaurasia SS, Tan DT, Mehta JS) Invest Ophthalmol Vis Sci 2012 May 04;53(6):2571-9 PMID: 22427557 03/20/2012       18 Citations
  • Femtosecond lenticule extraction (FLEx): clinical results, interface evaluation, and intraocular pressure variation. (Ang M, Chaurasia SS, Angunawela RI, Poh R, Riau A, Tan D, Mehta JS) Invest Ophthalmol Vis Sci 2012 Mar 15;53(3):1414-21 PMID: 22323464 02/11/2012       73 Citations
  • Cornea lenticule viability and structural integrity after refractive lenticule extraction (ReLEx) and cryopreservation. (Mohamed-Noriega K, Toh KP, Poh R, Balehosur D, Riau A, Htoon HM, Peh GS, Chaurasia SS, Tan DT, Mehta JS) Mol Vis 2011;17:3437-49 PMID: 22219639 PMCID: PMC3249438 01/06/2012       48 Citations
  • Optimization of Fibrin Glue Spray Systems for Ophthalmic Surgery. (Chaurasia SS, Champakalakshmi R, Angunawela RI, Tan DT, Mehta JS) Transl Vis Sci Technol 2012;1(2):2 PMID: 24049702 PMCID: PMC3763880 01/01/2012    
  • A mouse model of lamellar intrastromal femtosecond laser keratotomy: ultra-structural, inflammatory, and wound healing responses. (Angunawela RI, Poh R, Chaurasia SS, Tan DT, Mehta JS) Mol Vis 2011;17:3005-12 PMID: 22171154 PMCID: PMC3236073 12/16/2011       10 Citations
  • Meibum lipid composition in Asians with dry eye disease. (Lam SM, Tong L, Yong SS, Li B, Chaurasia SS, Shui G, Wenk MR) PLoS One 2011;6(10):e24339 PMID: 22043274 PMCID: PMC3197196 11/02/2011       98 Citations
  • A novel mutation in transforming growth factor-beta induced protein (TGFβIp) reveals secondary structure perturbation in lattice corneal dystrophy. (Lakshminarayanan R, Vithana EN, Chai SM, Chaurasia SS, Saraswathi P, Venkatraman A, Rojare C, Venkataraman D, Tan D, Aung T, Beuerman RW, Mehta JS) Br J Ophthalmol 2011 Oct;95(10):1457-62 PMID: 21835759 08/13/2011       21 Citations
  • Melatonin synthesis in retina: cAMP-dependent transcriptional regulation of chicken arylalkylamine N-acetyltransferase by a CRE-like sequence and a TTATT repeat motif in the proximal promoter. (Haque R, Chong NW, Ali F, Chaurasia SS, Sengupta T, Chun E, Howell JC, Klein DC, Iuvone PM) J Neurochem 2011 Oct;119(1):6-17 PMID: 21790603 PMCID: PMC3377444 07/28/2011       18 Citations
  • Dopamine D₄ receptor activation controls circadian timing of the adenylyl cyclase 1/cyclic AMP signaling system in mouse retina. (Jackson CR, Chaurasia SS, Hwang CK, Iuvone PM) Eur J Neurosci 2011 Jul;34(1):57-64 PMID: 21676039 PMCID: PMC3129439 06/17/2011       50 Citations
  • Early corneal wound healing and inflammatory responses after refractive lenticule extraction (ReLEx). (Riau AK, Angunawela RI, Chaurasia SS, Lee WS, Tan DT, Mehta JS) Invest Ophthalmol Vis Sci 2011 Aug 05;52(9):6213-21 PMID: 21666235 06/15/2011       104 Citations
  • Aberrant DNA methylation of matrix remodeling and cell adhesion related genes in pterygium. (Riau AK, Wong TT, Lan W, Finger SN, Chaurasia SS, Hou AH, Chen S, Yu SJ, Tong L) PLoS One 2011 Feb 16;6(2):e14687 PMID: 21359202 PMCID: PMC3040179 03/02/2011       37 Citations
  • Corneal wound healing after ultraviolet-A/riboflavin collagen cross-linking: a rabbit study. (Salomão MQ, Chaurasia SS, Sinha-Roy A, Ambrósio R Jr, Esposito A, Sepulveda R, Agrawal V, Wilson SE) J Refract Surg 2011 Jun;27(6):401-7 PMID: 21162471 12/18/2010       38 Citations
  • Hyperosmolarity-mediated mitochondrial dysfunction requires Transglutaminase-2 in human corneal epithelial cells. (Png E, Samivelu GK, Yeo SH, Chew J, Chaurasia SS, Tong L) J Cell Physiol 2011 Mar;226(3):693-9 PMID: 20717931 08/19/2010       25 Citations
  • Stromal interleukin-1 expression in the cornea after haze-associated injury. (Barbosa FL, Chaurasia SS, Kaur H, de Medeiros FW, Agrawal V, Wilson SE) Exp Eye Res 2010 Sep;91(3):456-61 PMID: 20603114 PMCID: PMC2952405 07/07/2010       37 Citations
  • Corneal myofibroblast generation from bone marrow-derived cells. (Barbosa FL, Chaurasia SS, Cutler A, Asosingh K, Kaur H, de Medeiros FW, Agrawal V, Wilson SE) Exp Eye Res 2010 Jul;91(1):92-6 PMID: 20417632 PMCID: PMC2887716 04/27/2010       77 Citations
  • In vivo real-time intraocular pressure variations during LASIK flap creation. (Chaurasia SS, Luengo Gimeno F, Tan K, Yu S, Tan DT, Beuerman RW, Mehta JS) Invest Ophthalmol Vis Sci 2010 Sep;51(9):4641-5 PMID: 20393112 04/16/2010       53 Citations
  • Screening for meibomian gland disease: its relation to dry eye subtypes and symptoms in a tertiary referral clinic in singapore. (Tong L, Chaurasia SS, Mehta JS, Beuerman RW) Invest Ophthalmol Vis Sci 2010 Jul;51(7):3449-54 PMID: 20181848 02/26/2010       64 Citations
  • Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo. (Ebrahem Q, Chaurasia SS, Vasanji A, Qi JH, Klenotic PA, Cutler A, Asosingh K, Erzurum S, Anand-Apte B) Am J Pathol 2010 Jan;176(1):496-503 PMID: 19948826 PMCID: PMC2797907 12/02/2009    
  • Effect of femtosecond laser energy level on corneal stromal cell death and inflammation. (de Medeiros FW, Kaur H, Agrawal V, Chaurasia SS, Hammel J, Dupps WJ Jr, Wilson SE) J Refract Surg 2009 Oct;25(10):869-74 PMID: 19835327 PMCID: PMC2769018 10/20/2009       57 Citations
  • Reprint of "Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury". (Chaurasia SS, Kaur H, de Medeiros FW, Smith SD, Wilson SE) Exp Eye Res 2009 Oct;89(4):590-6 PMID: 19747592 09/15/2009    
  • S156C mutation in tissue inhibitor of metalloproteinases-3 induces increased angiogenesis. (Qi JH, Dai G, Luthert P, Chaurasia S, Hollyfield J, Weber BH, Stöhr H, Anand-Apte B) J Biol Chem 2009 Jul 24;284(30):19927-36 PMID: 19478078 PMCID: PMC2740418 05/30/2009       31 Citations
  • Expression of PDGF receptor-alpha in corneal myofibroblasts in situ. (Kaur H, Chaurasia SS, Agrawal V, Wilson SE) Exp Eye Res 2009 Sep;89(3):432-4 PMID: 19344713 PMCID: PMC2720438 04/07/2009       11 Citations
  • Corneal myofibroblast viability: opposing effects of IL-1 and TGF beta1. (Kaur H, Chaurasia SS, Agrawal V, Suto C, Wilson SE) Exp Eye Res 2009 Aug;89(2):152-8 PMID: 19285499 PMCID: PMC2713809 03/17/2009       57 Citations
  • Dynamics of the expression of intermediate filaments vimentin and desmin during myofibroblast differentiation after corneal injury. (Chaurasia SS, Kaur H, de Medeiros FW, Smith SD, Wilson SE) Exp Eye Res 2009 Aug;89(2):133-9 PMID: 19285070 PMCID: PMC2716066 03/17/2009       63 Citations
  • Essential roles of dopamine D4 receptors and the type 1 adenylyl cyclase in photic control of cyclic AMP in photoreceptor cells. (Jackson CR, Chaurasia SS, Zhou H, Haque R, Storm DR, Iuvone PM) J Neurochem 2009 Apr;109(1):148-57 PMID: 19166506 PMCID: PMC2727872 01/27/2009       41 Citations
  • Corneal stroma PDGF blockade and myofibroblast development. (Kaur H, Chaurasia SS, de Medeiros FW, Agrawal V, Salomao MQ, Singh N, Ambati BK, Wilson SE) Exp Eye Res 2009 May;88(5):960-5 PMID: 19133260 PMCID: PMC2674136 01/10/2009       43 Citations
  • Expression of interleukin-1 receptor antagonist in human cornea. (Heur M, Chaurasia SS, Wilson SE) Exp Eye Res 2009 May;88(5):992-4 PMID: 19087877 PMCID: PMC2691719 12/18/2008       12 Citations
  • Haze development after photorefractive keratectomy: mechanical vs ethanol epithelial removal in rabbits. (de Medeiros FW, Mohan RR, Suto C, Sinhá S, Bonilha VL, Chaurasia SS, Wilson SE) J Refract Surg 2008 11;24(9):923-7 PMID: 19044233 12/03/2008       12 Citations
  • CLOCK is required for maintaining the circadian rhythms of Opsin mRNA expression in photoreceptor cells. (Li P, Chaurasia SS, Gao Y, Carr AL, Iuvone PM, Li L) J Biol Chem 2008 Nov 14;283(46):31673-8 PMID: 18687681 PMCID: PMC2581545 08/09/2008       20 Citations
  • Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea. (Stapleton WM, Chaurasia SS, Medeiros FW, Mohan RR, Sinha S, Wilson SE) Exp Eye Res 2008 May;86(5):753-7 PMID: 18346730 PMCID: PMC2693871 03/19/2008       38 Citations
  • Apoptosis in the initiation, modulation and termination of the corneal wound healing response. (Wilson SE, Chaurasia SS, Medeiros FW) Exp Eye Res 2007 Sep;85(3):305-11 PMID: 17655845 PMCID: PMC2039895 07/28/2007       106 Citations
  • Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex. (Luthra R, Kerr SC, Harreman MT, Apponi LH, Fasken MB, Ramineni S, Chaurasia S, Valentini SR, Corbett AH) J Biol Chem 2007 Feb 02;282(5):3042-9 PMID: 17158105 12/13/2006       95 Citations
  • Temporal coupling of cyclic AMP and Ca/calmodulin-stimulated adenylyl cyclase to the circadian clock in chick retinal photoreceptor cells. (Chaurasia SS, Haque R, Pozdeyev N, Jackson CR, Iuvone PM) J Neurochem 2006 Nov;99(4):1142-50 PMID: 16981891 PMCID: PMC2729135 09/20/2006       23 Citations
  • Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells. (Pozdeyev N, Taylor C, Haque R, Chaurasia SS, Visser A, Thazyeen A, Du Y, Fu H, Weller J, Klein DC, Iuvone PM) J Neurosci 2006 Sep 06;26(36):9153-61 PMID: 16957072 PMCID: PMC6674502 09/08/2006       37 Citations
  • Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates. (Bellingham J, Chaurasia SS, Melyan Z, Liu C, Cameron MA, Tarttelin EE, Iuvone PM, Hankins MW, Tosini G, Lucas RJ) PLoS Biol 2006 Jul;4(8):e254 PMID: 16856781 PMCID: PMC1514791 07/22/2006       147 Citations
  • Regulation of arylalkylamine N-acetyltransferase (AANAT) in the retina. (Tosini G, Chaurasia SS, Michael Iuvone P) Chronobiol Int 2006;23(1-2):381-91 PMID: 16687311 05/12/2006       31 Citations
  • Circadian clockwork machinery in neural retina: evidence for the presence of functional clock components in photoreceptor-enriched chick retinal cell cultures. (Chaurasia SS, Pozdeyev N, Haque R, Visser A, Ivanova TN, Iuvone PM) Mol Vis 2006 Mar 30;12:215-23 PMID: 16604054 04/11/2006       30 Citations
  • Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina. (Iuvone PM, Tosini G, Pozdeyev N, Haque R, Klein DC, Chaurasia SS) Prog Retin Eye Res 2005 Jul;24(4):433-56 PMID: 15845344 04/23/2005       271 Citations
  • Molecular cloning, localization and circadian expression of chicken melanopsin (Opn4): differential regulation of expression in pineal and retinal cell types. (Chaurasia SS, Rollag MD, Jiang G, Hayes WP, Haque R, Natesan A, Zatz M, Tosini G, Liu C, Korf HW, Iuvone PM, Provencio I) J Neurochem 2005 Jan;92(1):158-70 PMID: 15606905 12/21/2004       154 Citations
  • Temporal-spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues. (Chong NW, Chaurasia SS, Haque R, Klein DC, Iuvone PM) J Neurochem 2003 May;85(4):851-60 PMID: 12716417 04/30/2003       60 Citations
  • Diurnal regulation of arylalkylamine N-acetyltransferase activity in chicken retinal cells in vitro: analysis of culture conditions. (Haque R, Alonso-Gómez AL, Chaurasia SS, Iuvone PM) Mol Vis 2003 Mar 05;9:52-9 PMID: 12629487 03/12/2003       16 Citations
  • Dual regulation of cryptochrome 1 mRNA expression in chicken retina by light and circadian oscillators. (Haque R, Chaurasia SS, Wessel JH 3rd, Iuvone PM) Neuroreport 2002 Dec 03;13(17):2247-51 PMID: 12488805 12/19/2002       87 Citations
  • Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase. (Iuvone PM, Brown AD, Haque R, Weller J, Zawilska JB, Chaurasia SS, Ma M, Klein DC) Invest Ophthalmol Vis Sci 2002 Feb;43(2):564-72 PMID: 11818405 01/31/2002       63 Citations
  • Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse. (Chaurasia SS, Panda S, Kar A) Pharmacol Res 2000 Jun;41(6):663-6 PMID: 10816336 05/19/2000       37 Citations
  • Possible involvement of lipid peroxidation in the inhibition of type I iodothyronine 5'-monodeiodinase activity by lead in chicken liver. (Chaurasia SS, Gupta P, Maiti PK, Kar A) J Appl Toxicol 1998 Jul-Aug;18(4):299-300 PMID: 9719431 08/27/1998       5 Citations
  • Protective effects of vitamin E against lead-induced deterioration of membrane associated type-I iodothyronine 5'-monodeiodinase (5'D-I) activity in male mice. (Chaurasia SS, Kar A) Toxicology 1997 Dec 31;124(3):203-9 PMID: 9482122 03/03/1998       57 Citations
  • Influence of lead on type-I iodothyronine 5'-monodeiodinase activity in male mouse. (Chaurasia SS, Kar A) Horm Metab Res 1997 Oct;29(10):532-3 PMID: 9405984 12/24/1997       8 Citations
  • Cadmium induced alterations in extrathyroidal conversion of thyroxine to triiodothyronine by type-I iodothyronine 5'-monodeiodinase in male mouse. (Gupta P, Chaurasia SS, Maiti PK, Kar A) Horm Metab Res 1997 Mar;29(3):151-2 PMID: 9137987 03/01/1997       21 Citations
  • Dimethoate induced lipid peroxidation and inhibition of type-I iodothyronine 5'-monodeiodinase activity in young cockerel. (Maiti PK, Gupta P, Chaurasia SS, Kar A) Bull Environ Contam Toxicol 1996 Aug;57(2):335-40 PMID: 8661918 08/01/1996       15 Citations
  • Free radical mediated membrane perturbation and inhibition of type-I iodothyronine 5'-monodeiodinase activity by lead and cadmium in rat liver homogenate. (Chaurasia SS, Gupta P, Kar A, Maiti PK) Biochem Mol Biol Int 1996 Jul;39(4):765-70 PMID: 8843345 07/01/1996       48 Citations
  • Lead induced thyroid dysfunction and lipid peroxidation in the fish Clarias batrachus with special reference to hepatic type I-5'-monodeiodinase activity. (Chaurasia SS, Gupta P, Kar A, Maiti PK) Bull Environ Contam Toxicol 1996 Apr;56(4):649-54 PMID: 8645925 04/01/1996       36 Citations
  • Loss of membrane integrity and inhibition of type-I iodothyronine 5'-monodeiodinase activity by fenvalerate in female mouse. (Maiti PK, Kar A, Gupta P, Chaurasia SS) Biochem Biophys Res Commun 1995 Sep 25;214(3):905-9 PMID: 7575562 09/25/1995    
  • Last update: 02/15/2021